Publications 2025

Andresen MS, Mowinckel MC, Skarpen E, Andersen E, Sandset PM, Chollet ME, Stavik B (2025)
Identification and evaluation of Pharmacological enhancers of the factor VII p.Q160R variant
Sci Rep, 15 (1), 14315
DOI 10.1038/s41598-025-98689-3, PubMed 40274887

Publications 2024

Harrison SP, Baumgarten SF, Chollet ME, Stavik B, Bhattacharya A, Almaas R, Sullivan GJ (2024)
Parenteral nutrition emulsion inhibits CYP3A4 in an iPSC derived liver organoids testing platform
J Pediatr Gastroenterol Nutr, 78 (5), 1047-1058
DOI 10.1002/jpn3.12195, PubMed 38529852

Westerberg NS, Atneosen-Åsegg M, Melheim M, Chollet ME, Harrison SP, Siller R, Sullivan GJ, Almaas R (2024)
Effect of hypoxia on aquaporins and hepatobiliary transport systems in human hepatic cells
Pediatr Res, 97 (1), 195-201
DOI 10.1038/s41390-024-03368-0, PubMed 38951656

Publications 2023

Harrison SP, Siller R, Tanaka Y, Chollet ME, de la Morena-Barrio ME, Xiang Y, Patterson B, Andersen E, Bravo-Pérez C, Kempf H, Åsrud KS, Lunov O, Dejneka A, Mowinckel MC, Stavik B, Sandset PM, Melum E, Baumgarten S, Bonanini F, Kurek D, Mathapati S, Almaas R, Sharma K, Wilson SR, Skottvoll FS et al. (2023)
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039

Roman G, Stavik B, Lauritzen KH, Sandset PM, Harrison SP, Sullivan GJ, Chollet ME (2023)
"iPSC-derived liver organoids and inherited bleeding disorders: Potential and future perspectives"
Front Physiol, 14, 1094249
DOI 10.3389/fphys.2023.1094249, PubMed 36711019

Publications 2021

Andersen E, Chollet ME, Bernardi F, Branchini A, Baroni M, Mariani G, Dolce A, Batorova A, Skarpen E, Myklebust CF, Skretting G, Sandset PM (2021)
The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones
Appl. Sci.-Basel, 11 (13), 5762
DOI 10.3390/app11135762

Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N (2021)
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost, 121 (12), 1588-1598
DOI 10.1055/a-1450-8568, PubMed 33742435

Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909

Publications 2019

Andersen E, Chollet ME, Baroni M, Pinotti M, Bernardi F, Skarpen E, Sandset PM, Skretting G (2019)
The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII
Cell Biosci, 9, 69
DOI 10.1186/s13578-019-0333-8, PubMed 31467667

Publications 2018

Andersen E, Chollet ME, Myklebust CF, Pinotti M, Bernardi F, Chuansumrit A, Skarpen E, Sandset PM, Skretting G (2018)
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
Thromb Haemost, 118 (4), 664-675
DOI 10.1055/s-0038-1637690, PubMed 29618153

Publications 2017

Chollet ME, Andersen E, Skarpen E, Myklebust CF, Koehler C, Morth JP, Chuansumrit A, Pinotti M, Bernardi F, Thiede B, Sandset PM, Skretting G (2017)
Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain
Biochim Biophys Acta Mol Basis Dis, 1864 (3), 660-667
DOI 10.1016/j.bbadis.2017.12.016, PubMed 29246447

Publications 2015

Chollet ME, Skarpen E, Iversen N, Sandset PM, Skretting G (2015)
The chemical chaperone sodium 4-phenylbutyrate improves the secretion of the protein CA267T mutant in CHO-K1 cells trough the GRASP55 pathway
Cell Biosci, 5, 57
DOI 10.1186/s13578-015-0048-4, PubMed 26457178

Publications 2012

Woldt E, Terrand J, Mlih M, Matz RL, Bruban V, Coudane F, Foppolo S, El Asmar Z, Chollet ME, Ninio E, Bednarczyk A, Thiersé D, Schaeffer C, Van Dorsselaer A, Boudier C, Wahli W, Chambon P, Metzger D, Herz J, Boucher P (2012)
The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells
Nat Commun, 3, 1077
DOI 10.1038/ncomms2087, PubMed 23011131