Publications 2025

Hansen CD, Hansen JK, Israelsen M, Andersen P, Pikkupeura LM, Lindvig KP, Stinson SE, Schnefeld HL, Tellerup J, Fogt M, Torp N, Kjærgaard M, Bech KT, Thorhauge KH, Johansen S, Spedtsberg I, Deluran E, Villesen IF, Detlefsen S, Hansen T, Krag A, Thiele M (2025)
Prevalence, severity and determinants of steatotic liver disease among individuals with metabolic and alcohol risk from the community
J Hepatol (in press)
DOI 10.1016/j.jhep.2025.06.020, PubMed 40618958

Hansen JK, Israelsen M, Nishijima S, Stinson SE, Andersen P, Johansen S, Hansen CD, Brol MJ, Klein S, Schierwagen R, Uschner FE, Sulek K, Villesen IF, Lindvig KP, Thorhauge KH, Torp N, Jensen JM, Keller MI, Jensen GH, Detlefsen S, Leeming DJ, Stankevic E, Suvitaival T, Zawadzki A, Kuhn M et al. (2025)
The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial
Nat Commun, 16 (1), 5969
DOI 10.1038/s41467-025-60755-9, PubMed 40595534

Huang Y, Stinson SE, Thodberg M, Holm LA, Thielemann R, Sulek K, Lund MAV, Fonvig CE, Kim M, Trost K, Juel HB, Nielsen T, Rossing P, Thiele M, Krag A, Legido-Quigley C, Holm JC, Hansen T (2025)
Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescents
EBioMedicine, 112, 105537
DOI 10.1016/j.ebiom.2024.105537, PubMed 39753034

Jensen RT, Thuesen ACB, Huang Y, Stinson SE, Juel HB, Madsbad S, Bendtsen F, Hansen T, Pedersen JS (2025)
Changes in Inflammatory Markers Following Bariatric Surgery and the Impact of the Surgical Procedure: A 12-Month Longitudinal Study
Obes Surg, 35 (7), 2626-2637
DOI 10.1007/s11695-024-07629-z, PubMed 40423925

Niu L, Stinson SE, Holm LA, Lund MAV, Fonvig CE, Cobuccio L, Meisner J, Juel HB, Fadista J, Thiele M, Krag A, Holm JC, Rasmussen S, Hansen T, Mann M (2025)
Plasma proteome variation and its genetic determinants in children and adolescents
Nat Genet, 57 (3), 635-646
DOI 10.1038/s41588-025-02089-2, PubMed 39972214

Stæger FF, Andersen MK, Li Z, Hjerresen JP, He S, Santander CG, Jensen RT, Rex KF, Thuesen ACB, Hanghøj K, Seiding IH, Jørsboe E, Stinson SE, Rasmussen MS, Balboa RF, Larsen CVL, Bjerregaard P, Schubert M, Meisner J, Linneberg A, Grarup N, Zeggini E, Nielsen R, Jørgensen ME, Hansen T et al. (2025)
Genetic architecture in Greenland is shaped by demography, structure and selection
Nature, 639 (8054), 404-410
DOI 10.1038/s41586-024-08516-4, PubMed 39939757

Suleman S, Huang Y, Jensen RT, Poggi AI, Christensen SB, Fraulund MM, Anderson LV, Stinson SE, Fonvig CE, Pedersen O, Holm JC, Hansen T, Grarup N (2025)
Adult-based Genetic Risk Scores for Insulin Resistance Associate With Cardiometabolic Traits in Children and Adolescents
J Clin Endocrinol Metab, 110 (9), 2645-2654
DOI 10.1210/clinem/dgae882, PubMed 39690980

van der Meer D, Rahman Z, Ottas A, Parekh P, Kutrolli G, Stinson SE, Koromina M, Rokicki J, Sønderby IE, Parker N, Tesfaye M, Hindley G, Rødevand LN, Koch E, Estonian Biobank Research Team, Steen NE, Berg JP, O'Connell KS, Smeland OB, Frei O, Dale AM, Djurovic S, Lehto K, Alver M, Milani L et al. (2025)
Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers
Nat Commun, 16 (1), 4961
DOI 10.1038/s41467-025-60058-z, PubMed 40436851

Publications 2024

Huang Y, Sulek K, Stinson SE, Holm LA, Kim M, Trost K, Hooshmand K, Lund MAV, Fonvig CE, Juel HB, Nielsen T, Ängquist L, Rossing P, Thiele M, Krag A, Holm JC, Legido-Quigley C, Hansen T (2024)
Lipid profiling identifies modifiable signatures of cardiometabolic risk in children and adolescents with obesity
Nat Med, 31 (1), 294-305
DOI 10.1038/s41591-024-03279-x, PubMed 39304782

Kløve S, Stinson SE, Romme FO, Butt J, Graversen KB, Lund MAV, Fonvig CE, Waterboer T, Perez-Perez GI, Hansen T, Holm JC, Andersen SB (2024)
Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents
BMC Med, 22 (1), 379
DOI 10.1186/s12916-024-03591-w, PubMed 39256870

Kristensen JM, Kjøbsted R, Larsen TJ, Carl CS, Hingst JR, Onslev J, Birk JB, Thorup A, Steenberg DE, Knudsen JR, Henriksen NS, Needham EJ, Halling JF, Gudiksen A, Rundsten CF, Hanghøj KE, Stinson SE, Hoier B, Hansen CC, Jensen TE, Hellsten Y, Pilegaard H, Grarup N, Olesen J, Humphrey SJ et al. (2024)
Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise
Nat Metab, 6 (12), 2254-2266
DOI 10.1038/s42255-024-01153-1, PubMed 39482542

Stinson SE, Fernández de Retana Alzola I, Brünner Hovendal ED, Lund MAV, Fonvig CE, Holm LA, Jonsson AE, Frithioff-Bøjsøe C, Christiansen M, Pedersen O, Ängquist L, Sørensen TIA, Holst JJ, Hartmann B, Holm JC, Hansen T (2024)
Altered Glucagon and GLP-1 Responses to Oral Glucose in Children and Adolescents With Obesity and Insulin Resistance
J Clin Endocrinol Metab, 109 (6), 1590-1600
DOI 10.1210/clinem/dgad728, PubMed 38087928

Stinson SE, Kromann Reim P, Lund MAV, Lausten-Thomsen U, Aas Holm L, Huang Y, Brøns C, Vaag A, Thiele M, Krag A, Fonvig CE, Grarup N, Pedersen O, Christiansen M, Ängquist L, Sørensen TIA, Holm JC, Hansen T (2024)
The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
EBioMedicine, 105, 105205
DOI 10.1016/j.ebiom.2024.105205, PubMed 38918147

Thiele M, Villesen IF, Niu L, Johansen S, Sulek K, Nishijima S, Espen LV, Keller M, Israelsen M, Suvitaival T, Zawadzki A, Juel HB, Brol MJ, Stinson SE, Huang Y, Silva MCA, Kuhn M, Anastasiadou E, Leeming DJ, Karsdal M, Matthijnssens J, Arumugam M, Dalgaard LT, Legido-Quigley C, Mann M et al. (2024)
Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
J Hepatol, 81 (2), 345-359
DOI 10.1016/j.jhep.2024.03.035, PubMed 38552880

Zhu J, Eliasen AU, Aris IM, Stinson SE, Holm JC, Hansen T, Hivert MF, Bønnelykke K, Salem RM, Hirschhorn JN, Chan YM (2024)
Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome
J Clin Endocrinol Metab, 109 (2), 380-388
DOI 10.1210/clinem/dgad533, PubMed 37690116

Publications 2023

Andersen MK, Ängquist L, Bork-Jensen J, Jonsson AE, Stinson SE, Sandholt CH, Thodberg M, Pikkupeura LM, Ongstad EL, Grarup N, Astrup A, Pedersen O, Williams K, Barrès R, Sørensen TIA, Linneberg A, Grimsby J, Rhodes CJ, Hansen T (2023)
Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity
Diabetes Care, 46 (5), 985-992
DOI 10.2337/dc22-2078, PubMed 36809463

Beaumont RN, Flatley C, Vaudel M, Wu X, Chen J, Moen GH, Skotte L, Helgeland Ø, Solé-Navais P, Banasik K, Albiñana C, Ronkainen J, Fadista J, Stinson SE, Trajanoska K, Wang CA, Westergaard D, Srinivasan S, Sánchez-Soriano C, Bilbao JR, Allard C, Groleau M, Kuulasmaa T, Leirer DJ, White F et al. (2023)
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Nat Genet, 55 (11), 1807-1819
DOI 10.1038/s41588-023-01520-w, PubMed 37798380

Huang Y, Stinson SE, Juel HB, Lund MAV, Holm LA, Fonvig CE, Nielsen T, Grarup N, Pedersen O, Christiansen M, Chabanova E, Thomsen HS, Krag A, Stender S, Holm JC, Hansen T (2023)
An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents
Liver Int, 43 (8), 1772-1782
DOI 10.1111/liv.15613, PubMed 37208954

Stinson SE, Jonsson AE, Andersen MK, Lund MAV, Holm LA, Fonvig CE, Huang Y, Stankevič E, Juel HB, Ängquist L, Sørensen TIA, Ongstad EL, Gaddipati R, Grimsby J, Rhodes CJ, Pedersen O, Christiansen M, Holm JC, Hansen T (2023)
High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity
J Am Heart Assoc, 12 (3), e8145
DOI 10.1161/JAHA.122.027042, PubMed 36695299

Ullah A, Stankevic E, Holm LA, Stinson SE, Juel HB, Fonvig CE, Lund MAV, Trier C, Engelbrechtsen L, Ängquist L, Jonsson AE, Pedersen O, Grarup N, Holm JC, Hansen T (2023)
Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents
Antioxidants (Basel), 12 (8)
DOI 10.3390/antiox12081613, PubMed 37627608

Williamson A, Norris DM, Yin X, Broadaway KA, Moxley AH, Vadlamudi S, Wilson EP, Jackson AU, Ahuja V, Andersen MK, Arzumanyan Z, Bonnycastle LL, Bornstein SR, Bretschneider MP, Buchanan TA, Chang YC, Chuang LM, Chung RH, Clausen TD, Damm P, Delgado GE, de Mello VD, Dupuis J, Dwivedi OP, Erdos MR et al. (2023)
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake
Nat Genet, 55 (6), 973-983
DOI 10.1038/s41588-023-01408-9, PubMed 37291194

Publications 2022

Cuinat C, Stinson SE, Ward WE, Comelli EM (2022)
Maternal Intake of Probiotics to Program Offspring Health
Curr Nutr Rep, 11 (4), 537-562
DOI 10.1007/s13668-022-00429-w, PubMed 35986890

Stinson SE, Jonsson AE, de Retana Alzola IF, Lund MAV, Frithioff-Bøjsøe C, Aas Holm L, Fonvig CE, Pedersen O, Ängquist L, Sørensen TIA, Holst JJ, Christiansen M, Holm JC, Hartmann B, Hansen T (2022)
Hyperglucagonemia in Pediatric Adiposity Associates With Cardiometabolic Risk Factors but Not Hyperglycemia
J Clin Endocrinol Metab, 107 (6), 1569-1576
DOI 10.1210/clinem/dgac108, PubMed 35213713

Thuesen ACB, Stæger FF, Kaci A, Solheim MH, Aukrust I, Jørsboe E, Santander CG, Andersen MK, Li Z, Gilly A, Stinson SE, Gjesing AP, Bjerregaard P, Pedersen ML, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Bjørkhaug L, Njølstad PR, Albrechtsen A, Moltke I, Hansen T (2022)
A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
Lancet Reg Health Eur, 24, 100529
DOI 10.1016/j.lanepe.2022.100529, PubMed 36649380

Publications 2021

Ebbesen M, Kissow H, Hartmann B, Kielsen K, Sørensen K, Stinson SE, Frithioff-Bøjsøe C, Esmann Fonvig C, Holm JC, Hansen T, Holst JJ, Müller KG (2021)
Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation
Front Immunol, 12, 793588
DOI 10.3389/fimmu.2021.793588, PubMed 34956226

Jonsson A, Stinson SE, Torekov SS, Clausen TD, Færch K, Kelstrup L, Grarup N, Mathiesen ER, Damm P, Witte DR, Jørgensen ME, Pedersen O, Holst JJ, Hansen T (2021)
Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test
BMC Med Genomics, 14 (1), 3
DOI 10.1186/s12920-020-00841-7, PubMed 33407418

Lausten-Thomsen U, Lund MAV, Stinson SE, Frithioff-Bøjsøe C, Holm LA, Baker JL, Fonvig CE, Christiansen M, Ängquist L, Hansen T, Holm JC (2021)
Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents
J Pediatr, 242, 74-78.e2
DOI 10.1016/j.jpeds.2021.11.014, PubMed 34774572

Stinson SE, Jonsson AE, Lund MAV, Frithioff-Bøjsøe C, Aas Holm L, Pedersen O, Ängquist L, Sørensen TIA, Holst JJ, Christiansen M, Holm JC, Hartmann B, Hansen T (2021)
Fasting Plasma GLP-1 Is Associated With Overweight/Obesity and Cardiometabolic Risk Factors in Children and Adolescents
J Clin Endocrinol Metab, 106 (6), 1718-1727
DOI 10.1210/clinem/dgab098, PubMed 33596309

Publications 2019

Roth J, Stinson SE, Chan J, Barrowman N, Di Geso L (2019)
Differential pattern of Doppler signals at lower-extremity entheses of healthy children
Pediatr Radiol, 49 (10), 1335-1343
DOI 10.1007/s00247-019-04464-8, PubMed 31289909