Publications by Alf Håkon Lystad

28 publications found

  1. Lystad AH (2025)
    V-ATPase assembly at leaky lysosomes
    Nat Struct Mol Biol, 32 (10), 1862-1864
    DOI 10.1038/s41594-025-01612-7, PubMed 40646311
  2. Kaur N, Carlsson SR, Lystad AH (2025)
    Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms
    Front Cell Dev Biol, 13, 1559125
    DOI 10.3389/fcell.2025.1559125, PubMed 40213394
  3. Duran J, Salinas JE, Wheaton RP, Poolsup S, Allers L, Rosas-Lemus M, Chen L, Cheng Q, Pu J, Salemi M, Phinney B, Ivanov P, Lystad AH, Bhaskar K, Rajaiya J, Perkins DJ, Jia J (2024)
    Calcium signaling from damaged lysosomes induces cytoprotective stress granules
    EMBO J, 43 (24), 6410-6443
    DOI 10.1038/s44318-024-00292-1, PubMed 39533058
  4. Kaur N, Carlsson SR, Lystad AH (2023)
    The separate axes of TECPR1 and ATG16L1 in CASM
    Autophagy, 20 (1), 214-215
    DOI 10.1080/15548627.2023.2255462, PubMed 37676042
  5. Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
    TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
    EMBO J, 42 (17), e113105
    DOI 10.15252/embj.2022113105, PubMed 37409525
  6. Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
    Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
    EMBO J, 41 (24), e112677
    DOI 10.15252/embj.2022112677, PubMed 36408828
  7. Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
    Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Autophagy, 18 (11), 2547-2560
    DOI 10.1080/15548627.2022.2039535, PubMed 35220892
  8. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  9. Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V (2021)
    Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes
    Cell, 184 (24), 5950-5969.e22
    DOI 10.1016/j.cell.2021.10.017, PubMed 34741801
  10. Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
    Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
    Autophagy, 18 (7), 1486-1502
    DOI 10.1080/15548627.2021.1988359, PubMed 34740308
  11. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  12. Durgan J, Lystad AH, Sloan K, Carlsson SR, Wilson MI, Marcassa E, Ulferts R, Webster J, Lopez-Clavijo AF, Wakelam MJ, Beale R, Simonsen A, Oxley D, Florey O (2021)
    Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine
    Mol Cell, 81 (9), 2031-2040.e8
    DOI 10.1016/j.molcel.2021.03.020, PubMed 33909989
  13. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  14. Corkery DP, Nadeem A, Aung KM, Hassan A, Liu T, Cervantes-Rivera R, Lystad AH, Wang H, Persson K, Puhar A, Simonsen A, Uhlin BE, Wai SN, Wu YW (2021)
    Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy
    J Cell Sci, 134 (5)
    DOI 10.1242/jcs.252015, PubMed 33106317
  15. Hamaoui D, Cossé MM, Mohan J, Lystad AH, Wollert T, Subtil A (2020)
    The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1
    Proc Natl Acad Sci U S A, 117 (43), 26784-26794
    DOI 10.1073/pnas.2005389117, PubMed 33055216
  16. Melia TJ, Lystad AH, Simonsen A (2020)
    Autophagosome biogenesis: From membrane growth to closure
    J Cell Biol, 219 (6)
    DOI 10.1083/jcb.202002085, PubMed 32357219
  17. Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G, Dikic I (2019)
    TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease
    EMBO Rep, 21 (1), e48317
    DOI 10.15252/embr.201948317, PubMed 31709703
  18. Herzog LK, Kevei É, Marchante R, Böttcher C, Bindesbøll C, Lystad AH, Pfeiffer A, Gierisch ME, Salomons FA, Simonsen A, Hoppe T, Dantuma NP (2019)
    The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy
    Aging Cell, 19 (1), e13051
    DOI 10.1111/acel.13051, PubMed 31625269
  19. Lystad AH, Simonsen A (2019)
    Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery
    Cells, 8 (9)
    DOI 10.3390/cells8090973, PubMed 31450711
  20. Lystad AH, Carlsson SR, Simonsen A (2019)
    Toward the function of mammalian ATG12-ATG5-ATG16L1 complex in autophagy and related processes
    Autophagy, 15 (8), 1485-1486
    DOI 10.1080/15548627.2019.1618100, PubMed 31122169
  21. Lystad AH, Carlsson SR, de la Ballina LR, Kauffman KJ, Nag S, Yoshimori T, Melia TJ, Simonsen A (2019)
    Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes
    Nat Cell Biol, 21 (3), 372-383
    DOI 10.1038/s41556-019-0274-9, PubMed 30778222
  22. Kauffman KJ, Yu S, Jin J, Mugo B, Nguyen N, O'Brien A, Nag S, Lystad AH, Melia TJ (2018)
    Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases
    Autophagy, 14 (6), 992-1010
    DOI 10.1080/15548627.2018.1437341, PubMed 29458288
  23. Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
    HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
    Nat Commun, 7, 13889
    DOI 10.1038/ncomms13889, PubMed 28004827
  24. Dragich JM, Kuwajima T, Hirose-Ikeda M, Yoon MS, Eenjes E, Bosco JR, Fox LM, Lystad AH, Oo TF, Yarygina O, Mita T, Waguri S, Ichimura Y, Komatsu M, Simonsen A, Burke RE, Mason CA, Yamamoto A (2016)
    Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain
    Elife, 5
    DOI 10.7554/eLife.14810, PubMed 27648578
  25. Lystad AH, Simonsen A (2016)
    Phosphoinositide-binding proteins in autophagy
    FEBS Lett, 590 (15), 2454-68
    DOI 10.1002/1873-3468.12286, PubMed 27391591
  26. Lystad AH, Simonsen A (2014)
    Assays to monitor aggrephagy
    Methods, 75, 112-9
    DOI 10.1016/j.ymeth.2014.12.019, PubMed 25555675
  27. Lystad AH, Ichimura Y, Takagi K, Yang Y, Pankiv S, Kanegae Y, Kageyama S, Suzuki M, Saito I, Mizushima T, Komatsu M, Simonsen A (2014)
    Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures
    EMBO Rep, 15 (5), 557-65
    DOI 10.1002/embr.201338003, PubMed 24668264
  28. Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
    TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
    Autophagy, 9 (12), 1955-64
    DOI 10.4161/auto.26085, PubMed 24128730

 
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