
Bjørn Bendz
- Head of CCU; MD, PhD
- +47 23 07 06 44
Publications 2025
The effects of interleukin-6-receptor inhibition on monocytes in STEMI: a substudy of the ASSAIL-MI trial
121, 105960 (in press)
DOI 10.1016/j.ebiom.2025.105960, PubMed 41076990
Beta-Blockers after Myocardial Infarction in Patients without Heart Failure
(in press)
DOI 10.1056/NEJMoa2505985, PubMed 40888716
Publications 2024
The patient experience of in-hospital telemetry monitoring: a qualitative analysis
23 (3), 258-266
DOI 10.1093/eurjcn/zvad082, PubMed 37590960
Appropriateness and outcomes of hospitalized patients telemetry monitored for cardiac arrhythmias in accordance with the American Heart Association Practice Standards-A multicenter study
68, 217-226
DOI 10.1016/j.hrtlng.2024.07.005, PubMed 39067328
'When age is not a barrier': an explorative study of nonagenarian patients' experiences of undergoing percutaneous coronary intervention
23 (6), 608-617
DOI 10.1093/eurjcn/zvad132, PubMed 38243638
Non-ST-elevation acute coronary syndromes with previous coronary artery bypass grafting: a meta-analysis of invasive vs. conservative management
45 (27), 2380-2391
DOI 10.1093/eurheartj/ehae245, PubMed 38805681
Invasive vs. conservative management of older patients with non-ST-elevation acute coronary syndrome: individual patient data meta-analysis
45 (23), 2052-2062
DOI 10.1093/eurheartj/ehae151, PubMed 38596853
HoloPatch: improving intracardiac patch fit through holographically modelled templates
2 (3), qyae103
DOI 10.1093/ehjimp/qyae103, PubMed 39439746
Cardiac anatomic digital twins: findings from a single national centre
5 (6), 725-734
DOI 10.1093/ehjdh/ztae070, PubMed 39563912
Discharge Information About Adverse Drug Reactions Indicates Lower Self-Reported Adverse Drug Reactions and Fewer Concerns in Patients After Percutaneous Coronary Intervention
33 (3), 350-361
DOI 10.1016/j.hlc.2023.12.005, PubMed 38238118
Older women with non-ST-elevation acute coronary syndrome undergoing invasive or conservative management: an individual patient data meta-analysis
4 (6), oeae093
DOI 10.1093/ehjopen/oeae093, PubMed 39698149
Publications 2023
Long-Term Outcomes of Invasive vs Conservative Strategies for Older Patients With Non-ST-Segment Elevation Acute Coronary Syndromes
82 (21), 2021-2030
DOI 10.1016/j.jacc.2023.09.809, PubMed 37968019
An investigator-sponsored pragmatic randomized controlled trial of AntiCoagulation vs AcetylSalicylic Acid after Transcatheter Aortic Valve Implantation: Rationale and design of ACASA-TAVI
265, 225-232
DOI 10.1016/j.ahj.2023.08.010, PubMed 37634655
Phenotyping Self-Reported Health Profiles in Octogenarians and Nonagenarians After Percutaneous Coronary Intervention: A Latent Profile Analysis
32 (11), 1321-1333
DOI 10.1016/j.hlc.2023.09.004, PubMed 37925313
Effects of high-intensity interval training on cardiac remodelling, function and coronary microcirculation in de novo heart transplant patients: a substudy of the HITTS randomised controlled trial
9 (3), e001331
DOI 10.1136/bmjsem-2022-001331, PubMed 37440977
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
10 (2)
DOI 10.1136/openhrt-2023-002301, PubMed 37591633
Neuropsychological function is associated with hypocapnia at simulated high altitude
237 (4), e13949
DOI 10.1111/apha.13949, PubMed 36772955
Publications 2022
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
80, 104013
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178
TIMP-1 expression in coronary thrombi associate with myocardial injury in ST-elevation myocardial infarction patients
33 (6), 446-455
DOI 10.1097/MCA.0000000000001128, PubMed 35102064
Gene expression of fibrinolytic markers in coronary thrombi
20 (1), 23
DOI 10.1186/s12959-022-00383-1, PubMed 35488283
Novel regional longitudinal strain by speckle tracking to detect significant coronary artery disease in patients admitted to the emergency department for chest pain suggestive of acute coronary syndrome
20 (3), 166-177
DOI 10.1007/s12574-022-00568-7, PubMed 35290613
Two-year clinical outcomes after successful transcatheter aortic valve implantation with balloon-expandable versus self-expanding valves: A subanalysis of the GALILEO trial
100 (4), 636-645
DOI 10.1002/ccd.30370, PubMed 36040717
Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study
12 (9), e061689
DOI 10.1136/bmjopen-2022-061689, PubMed 36127123
Publications 2021
Outcome in refractory out-of-hospital cardiac arrest before and after implementation of an ECPR protocol
162, 35-42
DOI 10.1016/j.resuscitation.2021.01.038, PubMed 33581226
Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
77 (15), 1845-1855
DOI 10.1016/j.jacc.2021.02.049, PubMed 33858620
Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction
8 (1)
DOI 10.1136/openhrt-2020-001492, PubMed 33972404
The Inflammasome Signaling Pathway Is Actively Regulated and Related to Myocardial Damage in Coronary Thrombi from Patients with STEMI
2021, 5525917
DOI 10.1155/2021/5525917, PubMed 34135690
Prognostic impact of non-improvement of global longitudinal strain in patients with revascularized acute myocardial infarction
37 (12), 3477-3487
DOI 10.1007/s10554-021-02349-2, PubMed 34327649
A randomized clinical study using optical coherence tomography to evaluate the short-term effects of high-intensity interval training on cardiac allograft vasculopathy: a HITTS substudy
36 (1), e14488
DOI 10.1111/ctr.14488, PubMed 34747048
Incidence and risk factors for major bleeding among patients undergoing percutaneous coronary intervention: Findings from the Norwegian Coronary Stent Trial (NORSTENT)
16 (3), e0247358
DOI 10.1371/journal.pone.0247358, PubMed 33661918
Publications 2020
Acute coronary syndromes in older patients: does older age matter?
396 (10251), 585-587
DOI 10.1016/S0140-6736(20)31317-9, PubMed 32861295
Acute coronary syndromes in older patients: does older age matter?
Lancet, 396 (10251), 585-587
Periprocedural myocardial injury in the EXCEL trial
41 (17), 1703
DOI 10.1093/eurheartj/ehaa182, PubMed 32227182
Operative survival in patients with acute aortic disease in the era of newer oral anticoagulants
7 (2)
DOI 10.1136/openhrt-2020-001278, PubMed 32675298
Rethinking rehabilitation after percutaneous coronary intervention: a protocol of a multicentre cohort study on continuity of care, health literacy, adherence and costs at all care levels (the CONCARDPCI)
10 (2), e031995
DOI 10.1136/bmjopen-2019-031995, PubMed 32054625
The impact of semi-automatic versus manually adjusted assessment of global longitudinal strain in post-myocardial infarction patients
36 (7), 1283-1290
DOI 10.1007/s10554-020-01826-4, PubMed 32236908
Patients aged 80 years or older with non-ST-elevation myocardial infarction or unstable angina pectoris randomised to an invasive versus conservative strategy: angiographic and procedural results from the After Eighty study
7 (2)
DOI 10.1136/openhrt-2020-001256, PubMed 32719073
Publications 2019
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
6 (2), e001108
DOI 10.1136/openhrt-2019-001108, PubMed 31673391
Intra-aortic balloon pump in acute chest pain and cardiogenic shock - a long-term follow-up
53 (6), 337-341
DOI 10.1080/14017431.2019.1657938, PubMed 31476881
Mechanical dispersion as a marker of left ventricular dysfunction and prognosis in stable coronary artery disease
35 (7), 1265-1275
DOI 10.1007/s10554-019-01583-z, PubMed 31165941
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625
Publications 2018
Kateterbasert behandling av aortastenose - skrøpelighetsvurdering av pasienter.
Hjerteforum, 31 (3), 49-54
PublikaID 440
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
271, 1-7
DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572
BEtablocker Treatment After acute Myocardial Infarction in revascularized patients without reduced left ventricular ejection fraction (BETAMI): Rationale and design of a prospective, randomized, open, blinded end point study
208, 37-46
DOI 10.1016/j.ahj.2018.10.005, PubMed 30530121
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440
Challenges adhering to a medication regimen following first-time percutaneous coronary intervention: A patient perspective
88, 16-24
DOI 10.1016/j.ijnurstu.2018.07.013, PubMed 30165236
In Current Clinical Practice, after Percutaneous Coronary Intervention for Acute Myocardial Infarction, Are β-Blockers Prescribed for Heart Failure or as Secondary Prevention? A Pilot Study
140 (3), 152-154
DOI 10.1159/000490656, PubMed 30089282
Health-related quality of life in older patients with acute coronary syndrome randomised to an invasive or conservative strategy. The After Eighty randomised controlled trial
47 (1), 42-47
DOI 10.1093/ageing/afx121, PubMed 28985265
Publications 2017
Morbidity outcomes after surgical aortic valve replacement
4 (1), e000588
DOI 10.1136/openhrt-2017-000588, PubMed 28674629
Intra-Aortic Balloon Pump Optimizes Myocardial Function During Cardiogenic Shock
11 (3), 512-514
DOI 10.1016/j.jcmg.2017.05.019, PubMed 28823741
Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
52 (1), 43-50
DOI 10.1080/14017431.2017.1416157, PubMed 29233022
Effect of interleukin-6 inhibition on coronary microvascular and endothelial function in myocardial infarction
103 (19), 1521-1527
DOI 10.1136/heartjnl-2016-310875, PubMed 28432157
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
Acta Bioquim. Clin. Latinoam., 51 (3), 395-407
Publications 2016
Investigating near-death experiences
136 (23-24), 1968-1969
DOI 10.4045/tidsskr.16.0953, PubMed 28004543
Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease
375 (13), 1242-52
DOI 10.1056/NEJMoa1607991, PubMed 27572953
Long-term outcomes after transcatheter aortic valve implantation: the impact of intraoperative tissue Doppler echocardiography
23 (3), 403-9
DOI 10.1093/icvts/ivw159, PubMed 27241050
Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial
37 (30), 2406-13
DOI 10.1093/eurheartj/ehw171, PubMed 27161611
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
63 (2), 552-562
DOI 10.1373/clinchem.2016.261107, PubMed 27974383
Invasive strategy in acute coronary syndrome - Authors' reply
387 (10037), 2504
DOI 10.1016/S0140-6736(16)30673-0, PubMed 27353680
Re: Over 80 år og hjerteinfarkt
136 (16), 1324-5
DOI 10.4045/tidsskr.16.0685, PubMed 27637033
Invasive versus conservative strategy in patients aged 80 years or older with non-ST-elevation myocardial infarction or unstable angina pectoris (After Eighty study): an open-label randomised controlled trial
387 (10023), 1057-1065
DOI 10.1016/S0140-6736(15)01166-6, PubMed 26794722
Long-term effects of high-intensity interval training in heart transplant recipients: A 5-year follow-up study of a randomized controlled trial
31 (1)
DOI 10.1111/ctr.12868, PubMed 27865004
Publications 2015
Transcatheter aortic valve implantation and intraoperative left ventricular function: a myocardial tissue Doppler imaging study
29 (1), 115-20
DOI 10.1053/j.jvca.2014.10.016, PubMed 25620143
Intraoperative improvement in left ventricular peak systolic velocity predicts better short-term outcome after transcatheter aortic valve implantation
22 (1), 5-12
DOI 10.1093/icvts/ivv277, PubMed 26467639
Sensitive cardiac troponins and N-terminal pro-B-type natriuretic peptide in stable coronary artery disease: correlation with left ventricular function as assessed by myocardial strain
31 (5), 967-73
DOI 10.1007/s10554-015-0646-6, PubMed 25788439
Publications 2014
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13
234 (2), 352-9
DOI 10.1016/j.atherosclerosis.2014.03.021, PubMed 24732574
Publications 2013
Sensitive troponin assays and N-terminal pro-B-type natriuretic peptide in acute coronary syndrome: prediction of significant coronary lesions and long-term prognosis
165 (5), 716-24
DOI 10.1016/j.ahj.2013.02.008, PubMed 23622908
Layer-specific quantification of myocardial deformation by strain echocardiography may reveal significant CAD in patients with non-ST-segment elevation acute coronary syndrome
6 (5), 535-44
DOI 10.1016/j.jcmg.2013.01.009, PubMed 23582354
[New recommendations for the interpretation of troponin values]
133 (21), 2241-2
DOI 10.4045/tidsskr.13.0927, PubMed 24226329
[National guidelines for the interpretation of troponin values in the diagnosis of acute myocardial infarction]
133 (21), E1-6
DOI 10.4045/tidsskr.13.0647, PubMed 24226342
Publications 2012
The terminal part of the QT interval (T peak to T end): a predictor of mortality after acute myocardial infarction
17 (2), 85-94
DOI 10.1111/j.1542-474X.2012.00493.x, PubMed 22537325
Intravenous immunoglobulin does not reduce left ventricular remodeling in patients with myocardial dysfunction during hospitalization after acute myocardial infarction
168 (1), 212-8
DOI 10.1016/j.ijcard.2012.09.092, PubMed 23046599
Sequential ADP-stimulated light transmission and multiple electrode aggregometry in patients taking aspirin and clopidogrel after non ST-elevation myocardial infarction
72 (4), 318-25
DOI 10.3109/00365513.2012.666565, PubMed 22724626
Publications 2011
Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial
92 (2), 235-43
DOI 10.1097/TP.0b013e31822057f1, PubMed 21677600
[Don't withdraw all blood platelet inhibitors]
131 (8), 800; author reply 800
DOI 10.4045/tidsskr.11.0278, PubMed 21556070
Publications 2010
Turnuslegeboka 2010
Legeforl., Oslo (Ny rev. utg.), 458 s.
BIBSYS 102213836, ISBN 978-82-92934-05-0
Publications 2008
Prearrest administration of low-molecular-weight heparin in porcine cardiac arrest: hemodynamic effects and resuscitability
36 (3), 881-6
DOI 10.1097/CCM.0B013E318164E781, PubMed 18431276
Publications 2007
Turnuslegeboka
Legeforlaget, Oslo (4. utg.), 417 s.
BIBSYS 071016708, ISBN 978-82-993568-7-9
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization
115 (8), 972-80
DOI 10.1161/CIRCULATIONAHA.106.665893, PubMed 17283255
Publications 2005
Journal 1: om å skrive enda bedre medisinske journaler
Unipub, [Oslo], 71 s.
BIBSYS 052096033, ISBN 82-997039-0-5
[Primary angioplasty in acute ST elevation myocardial infarction in the elderly]
125 (21), 2922-4
PubMed 16276371
Publications 2004
Long-term prognosis after out-of-hospital cardiac arrest and primary percutaneous coronary intervention
63 (1), 49-53
DOI 10.1016/j.resuscitation.2004.04.006, PubMed 15451586
[Reduction of myocardial infarction size after primary percutaneous coronary intervention]
124 (10), 1387-9
PubMed 15195177
Publications 2003
Acute hypoxia and activation of coagulation
362 (9388), 997-8
DOI 10.1016/S0140-6736(03)14378-4, PubMed 14511938
Low levels of tissue factor pathway inhibitor (TFPI) increase the risk of venous thrombosis
101 (11), 4387-92
DOI 10.1182/blood-2002-10-3188, PubMed 12560220
[Prehospital ECG reduces time to treatment with percutaneous coronary interventions]
123 (10), 1353-4
PubMed 12806676
Publications 2002
[Air travel and venous thrombosis]
122 (16), 1579-81
PubMed 12119787
Air travel and risk of venous thromboembolism
108 (1), 15-7
DOI 10.1016/s0049-3848(02)00389-4, PubMed 12586126
[Left ventricular function and infarction size after primary angioplasty for acute myocardial infarction]
122 (24), 2350-4
PubMed 12448247
Reduced baroreceptor reflex sensitivity and increased blood pressure variability at 2400 m simulated cabin altitude
73 (7), 632-4
PubMed 12137097
Reduced baroreceptor reflex sensitivity and increased blood pressure variability at 2400 m simulated cabin altitude
Aviat. Space Environ. Med., 73 (7), 632-634
Publications 2001
Studies of tissue factor pathway inhibitor, heparin and hypobaric hypoxia
Haematological Research Laboratory, Ullevål University Hospital, Oslo, 1 b. (flere pag.)
BIBSYS 011971886, ISBN 82-497-0041-4
Hypobaric hypoxia - Reply
Lancet, 357 (9260), 955-956
DOI 10.1016/S0140-6736(05)71652-4
Deep-vein thrombosis in long-haul flights
358 (9284), 837-8; author reply 839
DOI 10.1016/S0140-6736(01)05978-5, PubMed 11570398
Low molecular weight heparin prevents activation of coagulation in a hypobaric environment
12 (5), 371-4
DOI 10.1097/00001721-200107000-00006, PubMed 11505080
Left ventricular function and infarct size 20 months after primary angioplasty for acute myocardial infarction
35 (6), 379-84
DOI 10.1080/14017430152754862, PubMed 11837517
[Angiographic results of primary angioplasty in acute myocardial infarction]
121 (7), 780-3
PubMed 11301697
[Hundred patients with acute myocardial infarction treated with primary angioplasty]
121 (7), 775-9
PubMed 11301696
[Long-term follow-up of 100 patients with acute myocardial infarction treated with angioplasty]
121 (25), 2930-2
PubMed 11715775
Reduced autonomic activity during stepwise exposure to high altitude
173 (4), 409-17
DOI 10.1046/j.1365-201X.2001.00925.x, PubMed 11903133
Publications 2000
A new sensitive chromogenic substrate assay of tissue factor pathway inhibitor type 1
97 (6), 463-72
DOI 10.1016/s0049-3848(99)00183-8, PubMed 10704656
Dose-dependent release of endogenous tissue factor pathway inhibitor by different low molecular weight heparins
11 (4), 343-8
DOI 10.1097/00001721-200006000-00005, PubMed 10847421
Reperfusion therapy and strategies in acute myocardial infarction
34 (4), 355-6
DOI 10.1080/14017430050196135, PubMed 10983665
Reperfusion therapy and strategies in acute myocardial infarction
Scand. Cardiovasc. J., 34 (4), 355-356
Association between acute hypobaric hypoxia and activation of coagulation in human beings
356 (9242), 1657-8
DOI 10.1016/S0140-6736(00)03165-2, PubMed 11089830
Physiological function of tissue factor pathway inhibitor and interaction with heparins
30 Suppl 2, 48-56
DOI 10.1159/000054163, PubMed 11251341
Physiological function of tissue factor pathway inhibitor and interaction with heparins
Haemostasis, 30 2, 48-56
Publications 1999
Partial depletion of tissue factor pathway inhibitor during subcutaneous administration of unfractionated heparin, but not with two low molecular weight heparins
107 (4), 756-62
DOI 10.1046/j.1365-2141.1999.01791.x, PubMed 10606880
[Angioplasty in heart arrest]
119 (23), 3410-3
PubMed 10553336
Serum phospholipids are the main environmental determinants of activated factor VII in the most common FVII genotype. European Union Concerted Action "Clotart"
84 (7), 620-6
PubMed 10406904
Hepatocyte growth factor in serum after injection of unfractionated and low molecular weight heparin in healthy individuals
105 (3), 641-7
DOI 10.1046/j.1365-2141.1999.01398.x, PubMed 10354124
Publications 1998
Differential effect of unfractionated heparin and low molecular weight heparin on intravascular tissue factor pathway inhibitor: evidence for a difference in antithrombotic action
101 (4), 638-46
DOI 10.1046/j.1365-2141.1998.00770.x, PubMed 9674734
[Angioplasty in acute myocardial infarction]
118 (5), 687-91
PubMed 9528363
Publications 1997
Tissue factor pathway inhibitor: clinical deficiency states
78 (1), 467-70
PubMed 9198198
Tissue factor pathway inhibitor: Clinical deficiency states
Thromb. Haemost., 78 (1), 467-470
Publications 1995
[Low prevalence of home respirator treatment in Norway]
110 (5), 148, 150
PubMed 7753604
[Artificial ventilation in the home. Experiences from a department of pulmonary medicine, Ullevål hospital]
115 (6), 699-702
PubMed 7900129