Publications
Publications published since 2006 from OUS - Department of Molecular Oncology (2006-2014 Dept of Cancer Prev.)
356 publications found
Publications 2024
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GRIN3A: A biomarker associated with a cribriform pattern and poor prognosis in prostate cancer
Neoplasia, 55, 101023
DOI 10.1016/j.neo.2024.101023, PubMed 38944914 -
Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC)
Eur Urol (in press)
DOI 10.1016/j.eururo.2024.09.017, PubMed 39394013 -
Outcomes of 10 years of PSA screening for prostate cancer in Norwegian men with Lynch syndrome
Prostate, 84 (10), 945-953
DOI 10.1002/pros.24711, PubMed 38629217 -
Results after Four Years of Screening for Prostate Cancer with PSA and MRI
N Engl J Med, 391 (12), 1083-1095
DOI 10.1056/NEJMoa2406050, PubMed 39321360 -
Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer
Nat Commun, 15 (1), 4342
DOI 10.1038/s41467-024-48706-2, PubMed 38773143 -
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
Cell Oncol (Dordr), 47 (4), 1267-1276
DOI 10.1007/s13402-024-00926-w, PubMed 38407700 -
Prognostic genome and transcriptome signatures in colorectal cancers
Nature, 633 (8028), 137-146
DOI 10.1038/s41586-024-07769-3, PubMed 39112715 -
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101 -
Evolutionary mode and timing of dissemination of high-grade serous carcinomas
JCI Insight, 9 (3)
DOI 10.1172/jci.insight.170423, PubMed 38175731 -
The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
Cell Mol Life Sci, 81 (1), 171
DOI 10.1007/s00018-024-05165-8, PubMed 38597989 -
Distinct longitudinal patterns of urine tumor DNA in patients undergoing surveillance for bladder cancer
Mol Oncol (in press)
DOI 10.1002/1878-0261.13639, PubMed 38720532
Publications 2023
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'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
Histopathology, 83 (6), 853-869
DOI 10.1111/his.15012, PubMed 37501635 -
Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
EBioMedicine, 97, 104829
DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931 -
PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data
Bioinformatics, 39 (1)
DOI 10.1093/bioinformatics/btac766, PubMed 36448696 -
Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood
Clin Epigenetics, 15 (1), 151
DOI 10.1186/s13148-023-01563-0, PubMed 37710283 -
Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer
JCO Clin Cancer Inform, 7, e2200159
DOI 10.1200/CCI.22.00159, PubMed 36821799 -
Endocytic trafficking of connexins in cancer pathogenesis
Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772
Publications 2022
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Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
Eur Urol, 83 (2), 183
DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529 -
Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer
Mod Pathol, 35 (9), 1236-1246
DOI 10.1038/s41379-022-01086-8, PubMed 35484226 -
Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
Int J Cancer, 152 (5), 945-951
DOI 10.1002/ijc.34226, PubMed 35880692 -
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
JCI Insight, 7 (4)
DOI 10.1172/jci.insight.155309, PubMed 35050902 -
Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk
Cancer Epidemiol Biomarkers Prev, 31 (9), 1769-1779
DOI 10.1158/1055-9965.EPI-22-0123, PubMed 35700037 -
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909 -
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045 -
Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only
N Engl J Med, 387 (23), 2126-2137
DOI 10.1056/NEJMoa2209454, PubMed 36477032 -
In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
Mol Oncol, 16 (15), 2810-2822
DOI 10.1002/1878-0261.13225, PubMed 35574900 -
Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193 -
miR-486-5p expression is regulated by DNA methylation in osteosarcoma
BMC Genomics, 23 (1), 142
DOI 10.1186/s12864-022-08346-6, PubMed 35172717 -
BladMetrix: a novel urine DNA methylation test with high accuracy for detection of bladder cancer in hematuria patients
Clin Epigenetics, 14 (1), 115
DOI 10.1186/s13148-022-01335-2, PubMed 36115961 -
Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
Clin Epigenetics, 14 (1), 77
DOI 10.1186/s13148-022-01287-7, PubMed 35701814 -
Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Eur Urol, 81 (4), 431
DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159 -
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
Cancer Gene Ther, 29 (8-9), 1276-1284
DOI 10.1038/s41417-022-00444-7, PubMed 35194199 -
NRF2 drives an oxidative stress response predictive of breast cancer
Free Radic Biol Med, 184, 170-184
DOI 10.1016/j.freeradbiomed.2022.03.029, PubMed 35381325
Publications 2021
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Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Sci Total Environ, 807 (Pt 1), 150697
DOI 10.1016/j.scitotenv.2021.150697, PubMed 34610396 -
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154 -
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
Mol Oncol, 16 (12), 2312-2329
DOI 10.1002/1878-0261.13159, PubMed 34890102 -
Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Sci Total Environ, 814, 152732
DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025 -
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Nat Commun, 12 (1), 891
DOI 10.1038/s41467-020-20670-7, PubMed 33563959 -
The chemical defensome of five model teleost fish
Sci Rep, 11 (1), 10546
DOI 10.1038/s41598-021-89948-0, PubMed 34006915 -
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
NPJ Genom Med, 6 (1), 59
DOI 10.1038/s41525-021-00223-7, PubMed 34262039 -
Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
Sci Rep, 11 (1), 23463
DOI 10.1038/s41598-021-02820-z, PubMed 34873230 -
Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
Biomarkers, 26 (4), 302-308
DOI 10.1080/1354750X.2021.1891291, PubMed 33645339 -
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
Neoplasia, 23 (6), 634-641
DOI 10.1016/j.neo.2021.05.012, PubMed 34107378 -
Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
J Transl Med, 19 (1), 384
DOI 10.1186/s12967-021-03062-3, PubMed 34496878 -
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666 -
Identification of 22 susceptibility loci associated with testicular germ cell tumors
Nat Commun, 12 (1), 4487
DOI 10.1038/s41467-021-24334-y, PubMed 34301922 -
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol, 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592 -
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667 -
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317 -
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693 -
Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
Br J Cancer, 126 (1), 48-56
DOI 10.1038/s41416-021-01586-5, PubMed 34671130
Publications 2020
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Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
ESMO Open, 5 (6), e001040
DOI 10.1136/esmoopen-2020-001040, PubMed 33219056 -
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin Cancer Res, 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813 -
Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
Int J Cancer, 148 (7), 1652-1657
DOI 10.1002/ijc.33425, PubMed 33284993 -
Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
Eur Urol Open Sci, 21, 51-60
DOI 10.1016/j.euros.2020.08.007, PubMed 34337468 -
Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas
Endocr Relat Cancer, 27 (9), 457-468
DOI 10.1530/ERC-20-0064, PubMed 32580154 -
Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
Mol Oncol, 14 (5), 1016-1027
DOI 10.1002/1878-0261.12668, PubMed 32171051 -
A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
Gastric Cancer, 23 (5), 811-823
DOI 10.1007/s10120-020-01064-6, PubMed 32215766 -
Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
EBioMedicine, 59, 102923
DOI 10.1016/j.ebiom.2020.102923, PubMed 32799124 -
Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis - The promise of DNA methylation and molecular biomarkers
JHEP Rep, 2 (5), 100143
DOI 10.1016/j.jhepr.2020.100143, PubMed 32939446 -
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
Blood Adv, 4 (9), 1859-1866
DOI 10.1182/bloodadvances.2019001325, PubMed 32374878 -
ScaR-a tool for sensitive detection of known fusion transcripts: establishing prevalence of fusions in testicular germ cell tumors
NAR Genom Bioinform, 2 (1), lqz025
DOI 10.1093/nargab/lqz025, PubMed 33575572
Publications 2019
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Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
Oncogene, 38 (33), 6109-6122
DOI 10.1038/s41388-019-0868-5, PubMed 31308487 -
Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
Eur J Surg Oncol, 45 (12), 2340-2346
DOI 10.1016/j.ejso.2019.07.017, PubMed 31350075 -
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
Clin Colorectal Cancer, 19 (1), e26-e47
DOI 10.1016/j.clcc.2019.09.003, PubMed 31982351 -
Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
Cell Death Dis, 10 (11), 818
DOI 10.1038/s41419-019-2057-4, PubMed 31659152 -
Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer
Sci Rep, 9 (1), 13579
DOI 10.1038/s41598-019-49964-7, PubMed 31537872 -
Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer
Ann Oncol, 30 (10), 1622-1629
DOI 10.1093/annonc/mdz287, PubMed 31504112 -
Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell-intrinsic properties
Int J Cancer, 144 (11), 2843-2853
DOI 10.1002/ijc.31998, PubMed 30447009 -
Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer
Cancer Lett, 469, 246-255
DOI 10.1016/j.canlet.2019.10.040, PubMed 31678167 -
Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
Br J Cancer, 121 (6), 474-482
DOI 10.1038/s41416-019-0540-4, PubMed 31388185 -
Correction: Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
Br J Cancer, 121 (9), 807
DOI 10.1038/s41416-019-0590-7, PubMed 31548598 -
Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach
Eur J Health Econ, 21 (3), 321-334
DOI 10.1007/s10198-019-01130-6, PubMed 31707584 -
Combination therapies with HSP90 inhibitors against colorectal cancer
Biochim Biophys Acta Rev Cancer, 1871 (2), 240-247
DOI 10.1016/j.bbcan.2019.01.002, PubMed 30708039 -
DNA-Methylation-Based Detection of Urological Cancer in Urine: Overview of Biomarkers and Considerations on Biomarker Design, Source of DNA, and Detection Technologies
Int J Mol Sci, 20 (11)
DOI 10.3390/ijms20112657, PubMed 31151158 -
Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
Lab Invest, 100 (1), 120-134
DOI 10.1038/s41374-019-0336-4, PubMed 31641225 -
Circulating biomarkers for early detection and clinical management of colorectal cancer
Mol Aspects Med, 69, 107-122
DOI 10.1016/j.mam.2019.06.002, PubMed 31189073 -
Cancer stemness, intratumoral heterogeneity, and immune response across cancers
Proc Natl Acad Sci U S A, 116 (18), 9020-9029
DOI 10.1073/pnas.1818210116, PubMed 30996127 -
GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
Cell Commun Signal, 17 (1), 140
DOI 10.1186/s12964-019-0467-7, PubMed 31694641 -
Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
HPB (Oxford), 21 (8), 1017-1023
DOI 10.1016/j.hpb.2018.12.003, PubMed 30765198 -
Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
ESMO Open, 4 (3), e000523
DOI 10.1136/esmoopen-2019-000523, PubMed 31321083 -
Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
Oncogenesis, 8 (6), 35
DOI 10.1038/s41389-019-0141-3, PubMed 31092812 -
Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes
Ann Oncol, 30 (11), 1682-1685
DOI 10.1093/annonc/mdz412, PubMed 31868904 -
Biomarker-guided therapy for colorectal cancer: strength in complexity
Nat Rev Clin Oncol, 17 (1), 11-32
DOI 10.1038/s41571-019-0241-1, PubMed 31289352 -
Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications
Cell Mol Life Sci, 77 (4), 573-591
DOI 10.1007/s00018-019-03285-0, PubMed 31501970 -
Connexins in cancer: bridging the gap to the clinic
Oncogene, 38 (23), 4429-4451
DOI 10.1038/s41388-019-0741-6, PubMed 30814684
Publications 2018
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Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
Mol Oncol, 12 (9), 1639-1655
DOI 10.1002/1878-0261.12347, PubMed 29900672 -
CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension
BMC Cancer, 18 (1), 68
DOI 10.1186/s12885-017-3948-3, PubMed 29321030 -
Prognostic markers for colorectal cancer: estimating ploidy and stroma
Ann Oncol, 29 (3), 616-623
DOI 10.1093/annonc/mdx794, PubMed 29293881 -
Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
Int J Cancer, 144 (4), 841-847
DOI 10.1002/ijc.31809, PubMed 30121958 -
Surgical options and trends in treating rectal prolapse: long-term results in a 19-year follow-up study
Langenbecks Arch Surg, 403 (8), 991-998
DOI 10.1007/s00423-018-1728-4, PubMed 30415286 -
Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53
Mod Pathol, 31 (11), 1694-1707
DOI 10.1038/s41379-018-0074-y, PubMed 29946184 -
Chromatin organisation and cancer prognosis: a pan-cancer study
Lancet Oncol, 19 (3), 356-369
DOI 10.1016/S1470-2045(17)30899-9, PubMed 29402700 -
White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk
Ann Intern Med, 168 (5), 326-334
DOI 10.7326/M17-0101, PubMed 29335712 -
Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
Eur Urol, 75 (3), 498-505
DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068 -
Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients
J Pathol, 244 (4), 421-431
DOI 10.1002/path.5026, PubMed 29282718 -
The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer
Transl Oncol, 11 (2), 436-443
DOI 10.1016/j.tranon.2018.01.015, PubMed 29475140 -
Post-discharge complications in frail older patients after surgery for colorectal cancer
Eur J Surg Oncol, 44 (10), 1542-1547
DOI 10.1016/j.ejso.2018.06.024, PubMed 30037638 -
Preoperative geriatric assessment and tailored interventions in frail older patients with colorectal cancer: a randomized controlled trial
Colorectal Dis, 20 (1), 16-25
DOI 10.1111/codi.13785, PubMed 28649755 -
Reply to Lawday et al
Colorectal Dis, 20 (4), 350-351
DOI 10.1111/codi.14059, PubMed 29502337 -
A robust internal control for high-precision DNA methylation analyses by droplet digital PCR
Clin Epigenetics, 10, 24
DOI 10.1186/s13148-018-0456-5, PubMed 29484034 -
Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation
Cancer Med, 7 (2), 433-444
DOI 10.1002/cam4.1285, PubMed 29341452 -
Complex Polygenic Nature of Testicular Germ Cell Cancer Suggests Multifactorial Aetiology
Eur Urol, 73 (6), 832-833
DOI 10.1016/j.eururo.2018.02.023, PubMed 29530636 -
CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer
Ann Oncol, 29 (5), 1227-1234
DOI 10.1093/annonc/mdy085, PubMed 29518181 -
Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer
Clin Epigenetics, 10, 70
DOI 10.1186/s13148-018-0503-2, PubMed 29854011 -
Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing
Cell, 174 (2), 433-447.e19
DOI 10.1016/j.cell.2018.05.036, PubMed 29909985
Publications 2017
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c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks
EBioMedicine, 18, 83-93
DOI 10.1016/j.ebiom.2017.04.006, PubMed 28412251 -
Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
Mol Cancer, 16 (1), 116
DOI 10.1186/s12943-017-0691-y, PubMed 28683746 -
Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
Ann Oncol, 28 (5), 1023-1031
DOI 10.1093/annonc/mdx052, PubMed 28453697 -
A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells
Cell Signal, 32, 1-11
DOI 10.1016/j.cellsig.2017.01.008, PubMed 28077322 -
CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models
Sci Rep, 7 (1), 16618
DOI 10.1038/s41598-017-16747-x, PubMed 29192179 -
MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
BMC Cancer, 17 (1), 97
DOI 10.1186/s12885-017-3094-y, PubMed 28158999 -
Lipid degradation promotes prostate cancer cell survival
Oncotarget, 8 (24), 38264-38275
DOI 10.18632/oncotarget.16123, PubMed 28415728 -
The expression of AURKA is androgen regulated in castration-resistant prostate cancer
Sci Rep, 7 (1), 17978
DOI 10.1038/s41598-017-18210-3, PubMed 29269934 -
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
Mol Oncol, 11 (9), 1156-1171
DOI 10.1002/1878-0261.12086, PubMed 28556483 -
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis, 19 (8), 731-738
DOI 10.1111/codi.13622, PubMed 28181384 -
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
PLoS One, 12 (7), e0182030
DOI 10.1371/journal.pone.0182030, PubMed 28759630 -
The connexin 43 C-terminus: A tail of many tales
Biochim Biophys Acta Biomembr, 1860 (1), 48-64
DOI 10.1016/j.bbamem.2017.05.008, PubMed 28526583 -
Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
Clin Epigenetics, 9, 97
DOI 10.1186/s13148-017-0397-4, PubMed 28878843 -
Details matter: the role of genomic location and assay standardization in DNA methylation analyses
Epigenomics, 9 (7), 933-935
DOI 10.2217/epi-2017-0053, PubMed 28617096 -
chimeraviz: a tool for visualizing chimeric RNA
Bioinformatics, 33 (18), 2954-2956
DOI 10.1093/bioinformatics/btx329, PubMed 28525538 -
An update on minding the gap in cancer
Biochim Biophys Acta Biomembr, 1860 (1), 237-243
DOI 10.1016/j.bbamem.2017.06.015, PubMed 28655619 -
Involvement of DPP9 in gene fusions in serous ovarian carcinoma
BMC Cancer, 17 (1), 642
DOI 10.1186/s12885-017-3625-6, PubMed 28893231 -
Epithelial-mesenchymal transition markers in malignant ovarian germ cell tumors
APMIS, 125 (9), 781-786
DOI 10.1111/apm.12715, PubMed 28585395 -
Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
Clin Cancer Res, 24 (4), 794-806
DOI 10.1158/1078-0432.CCR-17-1234, PubMed 29242316 -
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
Genome Med, 9 (1), 46
DOI 10.1186/s13073-017-0434-0, PubMed 28539123 -
The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
J Cell Sci, 130 (17), 2867-2882
DOI 10.1242/jcs.202408, PubMed 28733455 -
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
Cell Rep, 19 (10), 2045-2059
DOI 10.1016/j.celrep.2017.05.049, PubMed 28591577 -
Bromodomain-containing proteins in prostate cancer
Mol Cell Endocrinol, 462 (Pt A), 31-40
DOI 10.1016/j.mce.2017.06.007, PubMed 28624514 -
Epigenetic biomarkers in gastrointestinal cancers: The current state and clinical perspectives
Semin Cancer Biol, 51, 36-49
DOI 10.1016/j.semcancer.2017.12.004, PubMed 29253542 -
CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers
Int J Cancer, 141 (5), 967-976
DOI 10.1002/ijc.30796, PubMed 28542846 -
Novel transcription-induced fusion RNAs in prostate cancer
Oncotarget, 8 (30), 49133-49143
DOI 10.18632/oncotarget.17099, PubMed 28467780 -
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
BMC Genomics, 18 (1), 270
DOI 10.1186/s12864-017-3620-y, PubMed 28359301
Publications 2016
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Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Nat Rev Gastroenterol Hepatol, 13 (5), 261-80
DOI 10.1038/nrgastro.2016.51, PubMed 27095655 -
Mapping Protein-DNA Interactions Using ChIP-exo and Illumina-Based Sequencing
Methods Mol Biol, 1443, 119-37
DOI 10.1007/978-1-4939-3724-0_8, PubMed 27246337 -
Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
Cancer Med, 5 (8), 1840-9
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MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer
Oncotarget, 7 (6), 6476-505
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Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
Lancet Gastroenterol Hepatol, 1 (3), 207-216
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CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions
Nucleic Acids Res, 44 (22), 10588-10602
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Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
Cell Cycle, 15 (21), 2943-2957
DOI 10.1080/15384101.2016.1231280, PubMed 27625181 -
The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer
Tumour Biol, 37 (8), 10697-702
DOI 10.1007/s13277-016-4940-2, PubMed 26867771 -
Increased interleukin-6 expression is associated with poor prognosis and acquired cisplatin resistance in head and neck squamous cell carcinoma
Oncol Rep, 35 (6), 3265-74
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Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2
Biochem Biophys Res Commun, 476 (2), 102-7
DOI 10.1016/j.bbrc.2016.05.045, PubMed 27178209 -
Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli
Data Brief, 8, 733-40
DOI 10.1016/j.dib.2016.06.033, PubMed 27508226 -
Managing Malignant Colorectal Obstruction with Self-Expanding Stents. A Closer Look at Bowel Perforations and Failed Procedures
J Gastrointest Surg, 20 (9), 1643-9
DOI 10.1007/s11605-016-3186-z, PubMed 27342437 -
Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
Oncotarget, 7 (11), 12464-76
DOI 10.18632/oncotarget.7039, PubMed 26824323 -
Regulation of connexins by the ubiquitin system: Implications for intercellular communication and cancer
Biochim Biophys Acta, 1865 (2), 133-46
DOI 10.1016/j.bbcan.2016.02.001, PubMed 26855059 -
Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations
Oncotarget, 7 (5), 5273-88
DOI 10.18632/oncotarget.6567, PubMed 26672768 -
The importance of DNA methylation in prostate cancer development
J Steroid Biochem Mol Biol, 166, 1-15
DOI 10.1016/j.jsbmb.2016.04.009, PubMed 27117390 -
Cell cycle-coupled expansion of AR activity promotes cancer progression
Oncogene, 36 (12), 1655-1668
DOI 10.1038/onc.2016.334, PubMed 27669432 -
Observed correlation between the expression levels of catalytic subunit, Cβ2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness
Urol Oncol, 35 (3), 111.e1-111.e8
DOI 10.1016/j.urolonc.2016.10.002, PubMed 27838142 -
The role of glycans in the development and progression of prostate cancer
Nat Rev Urol, 13 (6), 324-33
DOI 10.1038/nrurol.2016.65, PubMed 27091662 -
Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
EBioMedicine, 8, 103-116
DOI 10.1016/j.ebiom.2016.04.018, PubMed 27428423 -
Experimental factors affecting the robustness of DNA methylation analysis
Sci Rep, 6, 33936
DOI 10.1038/srep33936, PubMed 27671843 -
Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1
Cancer Lett, 385, 150-159
DOI 10.1016/j.canlet.2016.10.028, PubMed 27984115 -
PBX3 is a putative biomarker of aggressive prostate cancer
Int J Cancer, 139 (8), 1810-20
DOI 10.1002/ijc.30220, PubMed 27273830 -
HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer
Oncotarget, 7 (46), 74734-74746
DOI 10.18632/oncotarget.12543, PubMed 27732966 -
Quality of life in older and frail patients after surgery for colorectal cancer-A follow-up study
J Geriatr Oncol, 7 (3), 195-200
DOI 10.1016/j.jgo.2016.03.002, PubMed 27067579 -
Bilateral ovarian carcinomas differ in the expression of metastasis-related genes
Oncol Lett, 13 (1), 184-190
DOI 10.3892/ol.2016.5384, PubMed 28123539 -
National Early Rectal Cancer Treatment Revisited
Dis Colon Rectum, 59 (7), 623-9
DOI 10.1097/DCR.0000000000000591, PubMed 27270514 -
Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection
PLoS Genet, 12 (7), e1006225
DOI 10.1371/journal.pgen.1006225, PubMed 27472274 -
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Epigenetics Chromatin, 9, 21
DOI 10.1186/s13072-016-0070-8, PubMed 27252783 -
Gene regulatory mechanisms underpinning prostate cancer susceptibility
Nat Genet, 48 (4), 387-97
DOI 10.1038/ng.3523, PubMed 26950096
Publications 2015
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Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426 -
Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
Hepatology, 61 (5), 1651-9
DOI 10.1002/hep.27707, PubMed 25644509 -
Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target
J Natl Cancer Inst, 108 (5)
DOI 10.1093/jnci/djv371, PubMed 26657335 -
Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer
Oncotarget, 6 (14), 12587-602
DOI 10.18632/oncotarget.3494, PubMed 25869206 -
Psychological distress related to BRCA testing in ovarian cancer patients
Fam Cancer, 14 (4), 495-504
DOI 10.1007/s10689-015-9811-2, PubMed 25980896 -
A differential protein solubility approach for the depletion of highly abundant proteins in plasma using ammonium sulfate
Analyst, 140 (24), 8109-17
DOI 10.1039/c5an01560j, PubMed 26541119 -
Exome sequencing of bilateral testicular germ cell tumors suggests independent development lineages
Neoplasia, 17 (2), 167-74
DOI 10.1016/j.neo.2014.12.005, PubMed 25748235 -
Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer
Clin Cancer Res, 21 (16), 3759-70
DOI 10.1158/1078-0432.CCR-14-3294, PubMed 25910952 -
The Evolutionary History of R2R3-MYB Proteins Across 50 Eukaryotes: New Insights Into Subfamily Classification and Expansion
Sci Rep, 5, 11037
DOI 10.1038/srep11037, PubMed 26047035 -
Nationwide improvement of rectal cancer treatment outcomes in Norway, 1993-2010
Acta Oncol, 54 (10), 1714-22
DOI 10.3109/0284186X.2015.1034876, PubMed 25924970 -
Identification of Novel Fusion Genes in Testicular Germ Cell Tumors
Cancer Res, 76 (1), 108-16
DOI 10.1158/0008-5472.CAN-15-1790, PubMed 26659575 -
Novel RNA variants in colorectal cancers
Oncotarget, 6 (34), 36587-602
DOI 10.18632/oncotarget.5500, PubMed 26474385 -
TIN: An R Package for Transcriptome Instability Analysis
Cancer Inform, 14, 109-12
DOI 10.4137/CIN.S31363, PubMed 26448683 -
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations
Oncotarget, 6 (23), 19661-70
DOI 10.18632/oncotarget.3875, PubMed 25965834 -
Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection
Mol Oncol, 9 (6), 1129-39
DOI 10.1016/j.molonc.2015.02.005, PubMed 25769404 -
BIR Pipeline for Preparation of Phylogenomic Data
Evol Bioinform Online, 11, 79-83
DOI 10.4137/EBO.S10189, PubMed 25987827 -
Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment
PLoS One, 10 (4), e0123684
DOI 10.1371/journal.pone.0123684, PubMed 25860483 -
Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts
Oncotarget, 6 (7), 5217-36
DOI 10.18632/oncotarget.2847, PubMed 25595908 -
Molecular subtyping of prostate cancer: a partnership model
Eur Urol, 68 (4), 568-9
DOI 10.1016/j.eururo.2015.05.012, PubMed 26001612 -
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Oncotarget, 6 (33), 34358-74
DOI 10.18632/oncotarget.6024, PubMed 26452038 -
Maintaining a Healthy Balance: Targeting TERT to Stem Benign Prostatic Hyperplasia
Eur Urol, 69 (4), 555-556
DOI 10.1016/j.eururo.2015.10.028, PubMed 26520704 -
Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study
EBioMedicine, 2 (9), 1133-44
DOI 10.1016/j.ebiom.2015.07.017, PubMed 26501111 -
Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs
Mol Cancer, 14, 153
DOI 10.1186/s12943-015-0411-4, PubMed 26265322 -
Macroautophagic cargo sequestration assays
Methods, 75, 25-36
DOI 10.1016/j.ymeth.2014.12.021, PubMed 25576638 -
Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes
Mol Cell Endocrinol, 412, 281-9
DOI 10.1016/j.mce.2015.05.015, PubMed 26001834 -
The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer
Eur Urol, 70 (2), 214-8
DOI 10.1016/j.eururo.2015.10.042, PubMed 26572708 -
Divergent androgen regulation of unfolded protein response pathways drives prostate cancer
EMBO Mol Med, 7 (6), 788-801
DOI 10.15252/emmm.201404509, PubMed 25864123 -
Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes
Oncogene, 35 (19), 2413-27
DOI 10.1038/onc.2015.318, PubMed 26300000 -
Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
Exp Cell Res, 333 (1), 21-38
DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710
Publications 2014
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Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential
J Cell Mol Med, 18 (11), 2287-97
DOI 10.1111/jcmm.12394, PubMed 25211630 -
Shared common variants in prostate cancer and blood lipids
Int J Epidemiol, 43 (4), 1205-14
DOI 10.1093/ije/dyu090, PubMed 24786909 -
Meta-analysis of prostate cancer gene expression data identifies a novel discriminatory signature enriched for glycosylating enzymes
BMC Med Genomics, 7, 513
DOI 10.1186/s12920-014-0074-9, PubMed 25551447 -
Androgen-regulated metabolism and biosynthesis in prostate cancer
Endocr Relat Cancer, 21 (4), T57-66
DOI 10.1530/ERC-13-0515, PubMed 24497572 -
A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma
PLoS One, 9 (9), e104249
DOI 10.1371/journal.pone.0104249, PubMed 25226156 -
Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer
Mol Cancer Res, 13 (4), 620-635
DOI 10.1158/1541-7786.MCR-13-0182-T, PubMed 25548099 -
Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
Front Oncol, 4, 118
DOI 10.3389/fonc.2014.00118, PubMed 24904831 -
Portrait of the PI3K/AKT pathway in colorectal cancer
Biochim Biophys Acta, 1855 (1), 104-21
DOI 10.1016/j.bbcan.2014.09.008, PubMed 25450577 -
Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis
Neuro Oncol, 17 (1), 63-9
DOI 10.1093/neuonc/nou140, PubMed 25038505 -
Endosomal signaling and oncogenesis
Methods Enzymol, 535, 179-200
DOI 10.1016/B978-0-12-397925-4.00012-2, PubMed 24377925 -
Prognostic impact of genomic instability in colorectal cancer
Br J Cancer, 110 (8), 2159-64
DOI 10.1038/bjc.2014.133, PubMed 24642618 -
UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation
Oncogene, 34 (28), 3744-50
DOI 10.1038/onc.2014.307, PubMed 25241896 -
Modeling and validating the cost and clinical pathway of colorectal cancer
Med Decis Making, 35 (2), 255-65
DOI 10.1177/0272989X14544749, PubMed 25073464 -
A novel transcript, VNN1-AB, as a biomarker for colorectal cancer
Int J Cancer, 135 (9), 2077-84
DOI 10.1002/ijc.28855, PubMed 24687856 -
HOXB13, RFX6 and prostate cancer risk
Nat Genet, 46 (2), 94-5
DOI 10.1038/ng.2881, PubMed 24473320 -
Maintaining and reprogramming genomic androgen receptor activity in prostate cancer
Nat Rev Cancer, 14 (3), 187-98
DOI 10.1038/nrc3678, PubMed 24561445 -
High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants
PLoS One, 9 (3), e91264
DOI 10.1371/journal.pone.0091264, PubMed 24608966 -
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
Biochem J, 461 (3), 383-90
DOI 10.1042/BJ20140132, PubMed 24840251 -
HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network
EMBO Mol Med, 6 (5), 651-61
DOI 10.1002/emmm.201303581, PubMed 24737870 -
The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer
Nucleic Acids Res, 42 (10), 6256-69
DOI 10.1093/nar/gku281, PubMed 24753418 -
Connexins in colorectal cancer pathogenesis
Int J Cancer, 137 (1), 1-11
DOI 10.1002/ijc.28911, PubMed 24752574 -
Chromosome 19 rearrangements in ovarian carcinomas: zinc finger genes are particularly targeted
Genes Chromosomes Cancer, 53 (7), 558-67
DOI 10.1002/gcc.22166, PubMed 24634323 -
Transcriptome instability as a molecular pan-cancer characteristic of carcinomas
BMC Genomics, 15 (1), 672
DOI 10.1186/1471-2164-15-672, PubMed 25109687 -
The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference
Int J Colorectal Dis, 29 (4), 419-28
DOI 10.1007/s00384-013-1818-2, PubMed 24477788 -
Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
Methods Mol Biol, 1105, 315-24
DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239 -
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int J Cancer, 136 (4), 844-53
DOI 10.1002/ijc.29039, PubMed 24948044 -
The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer
Epigenetics, 9 (3), 346-50
DOI 10.4161/epi.27582, PubMed 24384857 -
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer
EMBO J, 33 (12), 1365-82
DOI 10.15252/embj.201386874, PubMed 24837709
Publications 2013
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Epigenetic and genetic features of 24 colon cancer cell lines
Oncogenesis, 2 (9), e71
DOI 10.1038/oncsis.2013.35, PubMed 24042735 -
Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
Stem Cells Dev, 22 (7), 1136-46
DOI 10.1089/scd.2012.0369, PubMed 23137282 -
BCL-XL mediates the strong selective advantage of a 20q11.21 amplification commonly found in human embryonic stem cell cultures
Stem Cell Reports, 1 (5), 379-86
DOI 10.1016/j.stemcr.2013.10.005, PubMed 24286026 -
Novel 5' fusion partners of ETV1 and ETV4 in prostate cancer
Neoplasia, 15 (7), 720-6
DOI 10.1593/neo.13232, PubMed 23814484 -
Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I-III colon cancers
Mol Med, 19 (1), 286-93
DOI 10.2119/molmed.2013.00049, PubMed 23979710 -
Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma
PLoS One, 8 (11), e79602
DOI 10.1371/journal.pone.0079602, PubMed 24260260 -
Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
Epigenetics, 9 (3), 428-36
DOI 10.4161/epi.27554, PubMed 24362313 -
Meta-analysis identifies four new loci associated with testicular germ cell tumor
Nat Genet, 45 (6), 680-5
DOI 10.1038/ng.2634, PubMed 23666239 -
Modulation of intracellular calcium homeostasis blocks autophagosome formation
Autophagy, 9 (10), 1475-90
DOI 10.4161/auto.25900, PubMed 23970164 -
Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors
Neuro Oncol, 16 (2), 320-2
DOI 10.1093/neuonc/not230, PubMed 24311631 -
N-linked glycosylation supports cross-talk between receptor tyrosine kinases and androgen receptor
PLoS One, 8 (5), e65016
DOI 10.1371/journal.pone.0065016, PubMed 23724116 -
O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
Cancer Res, 73 (16), 5277-87
DOI 10.1158/0008-5472.CAN-13-0549, PubMed 23720054 -
Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis
Endocr Rev, 34 (3), 339-76
DOI 10.1210/er.2012-1045, PubMed 23575763 -
Assessment of fusion gene status in sarcomas using a custom made fusion gene microarray
PLoS One, 8 (8), e70649
DOI 10.1371/journal.pone.0070649, PubMed 23967081 -
Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes
Breast Cancer Res Treat, 138 (1), 37-45
DOI 10.1007/s10549-013-2408-2, PubMed 23329352 -
Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing
Transl Oncol, 6 (5), 546-53
DOI 10.1593/tlo.13457, PubMed 24151535 -
Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23
Hum Mol Genet, 22 (13), 2748-53
DOI 10.1093/hmg/ddt109, PubMed 23462292
Publications 2012
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ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
Gut, 61 (11), 1560-7
DOI 10.1136/gutjnl-2011-301179, PubMed 22213796 -
A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
Clin Transl Gastroenterol, 3 (12), e27
DOI 10.1038/ctg.2012.21, PubMed 23324654 -
Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
Epigenetics, 7 (11), 1249-57
DOI 10.4161/epi.22191, PubMed 22983262 -
Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma
PLoS One, 7 (11), e49819
DOI 10.1371/journal.pone.0049819, PubMed 23185447 -
MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
Neoplasia, 14 (9), 868-79
DOI 10.1593/neo.121094, PubMed 23019418 -
Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes
Genes Chromosomes Cancer, 51 (12), 1154-64
DOI 10.1002/gcc.22003, PubMed 22961909 -
NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
Cell Signal, 25 (1), 12-8
DOI 10.1016/j.cellsig.2012.08.012, PubMed 22974840 -
Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
J Cell Sci, 125 (Pt 17), 3966-76
DOI 10.1242/jcs.093500, PubMed 22623726 -
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis
Proc Natl Acad Sci U S A, 109 (28), 11252-7
DOI 10.1073/pnas.1200853109, PubMed 22730461 -
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
J Clin Invest, 122 (12), 4621-34
DOI 10.1172/JCI62973, PubMed 23143306 -
MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
J Transl Med, 10, 36
DOI 10.1186/1479-5876-10-36, PubMed 22390413 -
The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation
J Biol Chem, 287 (19), 15851-61
DOI 10.1074/jbc.M111.281832, PubMed 22411987 -
Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1
Neuro Oncol, 15 (2), 135-47
DOI 10.1093/neuonc/nos287, PubMed 23161774 -
A comparison of two pre-operative frailty measures in older surgical cancer patients
J. Geriatr. Oncol., 3 (1), 1-7
DOI 10.1016/j.jgo.2011.09.002 -
Vimentin in upper gastrointestinal pathologies--letter
Cancer Epidemiol Biomarkers Prev, 21 (10), 1889; author reply 1890
DOI 10.1158/1055-9965.EPI-12-0894, PubMed 22929079 -
The mitochondrial and autosomal mutation landscapes of prostate cancer
Eur Urol, 63 (4), 702-8
DOI 10.1016/j.eururo.2012.11.053, PubMed 23265383 -
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
EMBO Rep, 14 (1), 10-1
DOI 10.1038/embor.2012.188, PubMed 23229585 -
Oncogenicity of the developmental transcription factor Sox9
Cancer Res, 72 (5), 1301-15
DOI 10.1158/0008-5472.CAN-11-3660, PubMed 22246670 -
Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
Ann Oncol, 24 (5), 1274-82
DOI 10.1093/annonc/mds614, PubMed 23235802 -
Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients
Ann Surg Oncol, 19 (12), 3719-26
DOI 10.1245/s10434-012-2454-8, PubMed 22752373 -
Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
PLoS One, 7 (11), e49705
DOI 10.1371/journal.pone.0049705, PubMed 23185413 -
Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements
Neoplasia, 14 (7), 600-11
DOI 10.1593/neo.12600, PubMed 22904677 -
The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
Cancer Cell, 23 (1), 35-47
DOI 10.1016/j.ccr.2012.11.010, PubMed 23260764 -
Prognostic impact of lymph node harvest and lymph node ratio in patients with colon cancer
Dis Colon Rectum, 55 (3), 307-15
DOI 10.1097/DCR.0b013e3182423f62, PubMed 22469798 -
The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
Int J Cancer, 131 (6), 1479-85
DOI 10.1002/ijc.27399, PubMed 22173985 -
ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
Clin Cancer Res, 18 (21), 6001-10
DOI 10.1158/1078-0432.CCR-11-3302, PubMed 22991413
Publications 2011
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Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors
Endocr Relat Cancer, 18 (6), C31-4
DOI 10.1530/ERC-11-0204, PubMed 21868474 -
The testicular germ cell tumour transcriptome
Int J Androl, 34 (4 Pt 2), e133-50; discussion e150-1
DOI 10.1111/j.1365-2605.2011.01169.x, PubMed 21651573 -
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers
Epigenetics, 6 (9), 1120-30
DOI 10.4161/epi.6.9.16376, PubMed 21847011 -
Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
PLoS One, 6 (9), e24419
DOI 10.1371/journal.pone.0024419, PubMed 21909432 -
Clinical prediction of survival by surgeons for patients with incurable abdominal malignancy
Eur J Surg Oncol, 37 (7), 571-5
DOI 10.1016/j.ejso.2011.02.009, PubMed 21444178 -
Ischemia induces closure of gap junctional channels and opening of hemichannels in heart-derived cells and tissue
Cell Physiol Biochem, 28 (1), 103-14
DOI 10.1159/000331719, PubMed 21865853 -
Endocytosis and post-endocytic sorting of connexins
Biochim Biophys Acta, 1818 (8), 1870-9
DOI 10.1016/j.bbamem.2011.09.029, PubMed 21996040 -
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
Mol Cancer, 10, 85
DOI 10.1186/1476-4598-10-85, PubMed 21777459 -
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
DOI 10.1038/onc.2011.109, PubMed 21499309 -
Fusion gene microarray reveals cancer type-specificity among fusion genes
Genes Chromosomes Cancer, 50 (5), 348-57
DOI 10.1002/gcc.20860, PubMed 21305644 -
Nuclear translocation and functions of growth factor receptors
Semin Cell Dev Biol, 23 (2), 165-71
DOI 10.1016/j.semcdb.2011.09.004, PubMed 21930229 -
MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
BMC Cancer, 11, 211:1-11
DOI 10.1186/1471-2407-11-211, PubMed 21624110 -
FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer
Genes Chromosomes Cancer, 51 (3), 240-9
DOI 10.1002/gcc.20948, PubMed 22081504 -
Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene
PLoS One, 6 (7), e22317
DOI 10.1371/journal.pone.0022317, PubMed 21814574 -
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
DOI 10.1371/journal.pone.0017086, PubMed 21455500 -
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int J Cancer, 131 (3), 570-81
DOI 10.1002/ijc.26392, PubMed 21866551 -
DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
Epigenetics, 6 (5), 602-9
DOI 10.4161/epi.6.5.15237, PubMed 21406965 -
Peritoneal carcinomatosis of colon cancer origin: highest incidence in women and in patients with right-sided tumors
J Surg Oncol, 104 (7), 792-7
DOI 10.1002/jso.21959, PubMed 21547915 -
Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
Genome Med, 3 (5), 32
DOI 10.1186/gm248, PubMed 21619627 -
CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
Genes Immun, 12 (8), 653-62
DOI 10.1038/gene.2011.43, PubMed 21716316
Publications 2010
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Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
Mol Cancer, 9, 100
DOI 10.1186/1476-4598-9-100, PubMed 20459617 -
DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
PLoS One, 5 (11), e13978
DOI 10.1371/journal.pone.0013978, PubMed 21103049 -
Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma
Amino Acids, 41 (4), 875-84
DOI 10.1007/s00726-010-0514-6, PubMed 20191297 -
Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group
J Clin Oncol, 28 (9), 1573-82
DOI 10.1200/JCO.2009.24.8989, PubMed 20159821 -
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
J Carcinog, 9, 1
DOI 10.4103/1477-3163.60358, PubMed 20411023 -
Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples
Clin Cancer Res, 16 (23), 5842-51
DOI 10.1158/1078-0432.CCR-10-1312, PubMed 20975101 -
Regulation of gap junction intercellular communication by the ubiquitin system
Cell Signal, 22 (9), 1267-73
DOI 10.1016/j.cellsig.2010.03.005, PubMed 20206687 -
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
DOI 10.4161/auto.6.7.13033, PubMed 20724836 -
Which elements of a comprehensive geriatric assessment (CGA) predict post-operative complications and early mortality after colorectal cancer surgery?
J. Geriatr. Oncol., 1 (2), 57-65
DOI 10.1016/j.jgo.2010.06.001 -
Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
Toxicol Appl Pharmacol, 247 (1), 10-7
DOI 10.1016/j.taap.2010.05.006, PubMed 20510257 -
Genomic aberrations in borderline ovarian tumors
J Transl Med, 8, 21
DOI 10.1186/1479-5876-8-21, PubMed 20184781 -
Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes
Genes Chromosomes Cancer, 49 (11), 1046-53
DOI 10.1002/gcc.20813, PubMed 20725991 -
[Pilonidal disease--an underprioritized disorder]
Tidsskr Nor Laegeforen, 130 (9), 920
DOI 10.4045/tidsskr.10.0376, PubMed 20453940 -
Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin
BMC Cancer, 10, 587
DOI 10.1186/1471-2407-10-587, PubMed 20979647 -
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
DOI 10.1038/ncb2036, PubMed 20208530 -
Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials
Curr Opin Mol Ther, 12 (6), 703-11
PubMed 21154162
Publications 2009
-
Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours
J Pathol, 217 (5), 693-701
DOI 10.1002/path.2494, PubMed 19142971 -
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660 -
Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors
Neuro Oncol, 11 (5), 514-28
DOI 10.1215/15228517-2008-127, PubMed 19182148 -
Novel Mutations of the Suppressor Gene PTEN in Colorectal Carcinomas Stratified by Microsatellite Instability- and TP53 Mutation- Status (vol 29, pg E252, 2008)
Hum. Mutat., 30 (6), 1023
DOI 10.1002/humu.21048 -
The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma
Mol Hum Reprod, 15 (8), 479-88
DOI 10.1093/molehr/gap040, PubMed 19505997 -
Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
Pharmacogenet Genomics, 19 (10), 751-9
DOI 10.1097/FPC.0b013e3283304253, PubMed 19741569 -
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
DOI 10.1242/jcs.053801, PubMed 19808888 -
Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution
J Oncol, 2010, 646340
DOI 10.1155/2010/646340, PubMed 19759843 -
Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map
Genes Chromosomes Cancer, 48 (2), 184-93
DOI 10.1002/gcc.20628, PubMed 18973136 -
Large scale genomic instability as an additive prognostic marker in early prostate cancer
Cell Oncol, 31 (4), 251-9
DOI 10.3233/CLO-2009-0463, PubMed 19633362 -
Gap junction intercellular communication and benzene toxicity
Chem Biol Interact, 184 (1-2), 229-32
DOI 10.1016/j.cbi.2009.11.013, PubMed 19932693 -
Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
Biochem Biophys Res Commun, 382 (1), 41-5
DOI 10.1016/j.bbrc.2009.02.141, PubMed 19258009 -
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
Mol Cancer, 8, 5
DOI 10.1186/1476-4598-8-5, PubMed 19152679 -
The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis
Toxicol Appl Pharmacol, 242 (2), 231-40
DOI 10.1016/j.taap.2009.10.012, PubMed 19874837
Publications 2008
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RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
Neoplasia, 10 (7), 680-6, 2 p following 686
DOI 10.1593/neo.08312, PubMed 18592002 -
Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
Mol Cancer, 7, 94
DOI 10.1186/1476-4598-7-94, PubMed 19117505 -
TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours
Mol Cell Endocrinol, 306 (1-2), 75-80
DOI 10.1016/j.mce.2008.10.043, PubMed 19041365 -
Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
Hum Mutat, 29 (11), E252-62
DOI 10.1002/humu.20860, PubMed 18781614 -
Sentinel node mapping does not improve staging of lymph node metastasis in colonic cancer
Dis Colon Rectum, 51 (6), 891-6
DOI 10.1007/s10350-007-9185-0, PubMed 18259817 -
The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications
BMC Cancer, 8, 172
DOI 10.1186/1471-2407-8-172, PubMed 18554396 -
[Should platelet inhibitors be discontinued before gastrointestinal endoscopy?]
Tidsskr Nor Laegeforen, 128 (21), 2440-2
PubMed 19096466 -
Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues
Genome Biol, 9 (9), R139
DOI 10.1186/gb-2008-9-9-r139, PubMed 18803840 -
Hypermethylated MAL gene - a silent marker of early colon tumorigenesis
J Transl Med, 6, 13
DOI 10.1186/1479-5876-6-13, PubMed 18346269 -
The benzene metabolite trans,trans-muconaldehyde blocks gap junction intercellular communication by cross-linking connexin43
Toxicol Appl Pharmacol, 232 (3), 463-8
DOI 10.1016/j.taap.2008.07.022, PubMed 18723040 -
The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
Biochem Biophys Res Commun, 373 (4), 597-601
DOI 10.1016/j.bbrc.2008.06.095, PubMed 18601906
Publications 2007
-
Improved gene expression signature of testicular carcinoma in situ
Int J Androl, 30 (4), 292-302; discussion 303
DOI 10.1111/j.1365-2605.2007.00758.x, PubMed 17488342 -
Evolutionary selection pressure and family relationships among connexin genes
Biol Chem, 388 (3), 253-64
DOI 10.1515/BC.2007.028, PubMed 17338632 -
Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers
Mol Cancer, 6, 12
DOI 10.1186/1476-4598-6-12, PubMed 17274819 -
[Colorectal polyps]
Tidsskr Nor Laegeforen, 127 (20), 2692-5
PubMed 17952154 -
Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
Mol Cancer, 6, 2
DOI 10.1186/1476-4598-6-2, PubMed 17201907 -
Ubiquitination of gap junction proteins
J Membr Biol, 217 (1-3), 43-51
DOI 10.1007/s00232-007-9050-z, PubMed 17657522 -
DNA hypermethylation of MAL: a promising diagnostic biomarker for colorectal tumors
Gastroenterology, 132 (4), 1631-2; author reply 1632
DOI 10.1053/j.gastro.2007.03.003, PubMed 17408629 -
The epigenome of testicular germ cell tumors
APMIS, 115 (10), 1147-60
DOI 10.1111/j.1600-0463.2007.apm_660.xml.x, PubMed 18042148 -
Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
J Transl Med, 5, 70
DOI 10.1186/1479-5876-5-70, PubMed 18162130 -
Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors
J Clin Oncol, 25 (6), 708-14
DOI 10.1200/JCO.2006.08.9599, PubMed 17228018 -
Slip slidin' away: a duodecennial review of targeted genes in mismatch repair deficient colorectal cancer
Crit Rev Oncog, 13 (3), 229-57
DOI 10.1615/critrevoncog.v13.i3.20, PubMed 18298386 -
Tumour location is a prognostic factor for survival in colonic cancer patients
Colorectal Dis, 10 (1), 33-40
DOI 10.1111/j.1463-1318.2007.01302.x, PubMed 17672872 -
Alternative splicing in cancer: noise, functional, or systematic?
Int J Biochem Cell Biol, 39 (7-8), 1432-49
DOI 10.1016/j.biocel.2007.02.016, PubMed 17416541 -
[Surgical treatment of morbid obesity at a regional center]
Tidsskr Nor Laegeforen, 127 (1), 47-9
PubMed 17205090 -
The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers
Epigenetics, 2 (4), 237-43
DOI 10.4161/epi.2.4.5406, PubMed 18281782 -
DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
Mol Cancer, 6, 45
DOI 10.1186/1476-4598-6-45, PubMed 17623056
Publications 2006
-
Diagnostic and prognostic value of molecular cytogenetic analyses of sextant biopsies from prostate cancer suspects
Crit Rev Oncog, 12 (3-4), 303-4; discussion 304
DOI 10.1615/critrevoncog.v12.i3-4.100, PubMed 17425511 -
The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
Genes Chromosomes Cancer, 45 (1), 31-41
DOI 10.1002/gcc.20261, PubMed 16145679 -
Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study
Ann Oncol, 17 (5), 842-7
DOI 10.1093/annonc/mdl035, PubMed 16524972 -
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
Cancer Res, 66 (21), 10242-6
DOI 10.1158/0008-5472.CAN-06-1986, PubMed 17079440 -
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
DOI 10.1042/BJ20050674, PubMed 16162097 -
Downregulation of gap junctions in cancer cells
Crit Rev Oncog, 12 (3-4), 225-56
DOI 10.1615/critrevoncog.v12.i3-4.30, PubMed 17425504 -
ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
Cell Oncol, 28 (5-6), 259-72
DOI 10.1155/2006/949506, PubMed 17167179 -
ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
Cell. Oncol., 28 (5-6), 259-272 -
Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)
J Pathol, 210 (4), 441-9
DOI 10.1002/path.2064, PubMed 17029216 -
To the Readers and Future Authors of Critical Reviews in Oncogenesis
Critical Reviews in Oncogenesis, 12 (1-2), 1-2
PublikaID 27 -
Statistical dissection of genetic pathways involved in prostate carcinogenesis
Genes Chromosomes Cancer, 45 (2), 154-63
DOI 10.1002/gcc.20279, PubMed 16235241 -
Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
Mol Cancer, 5, 33
DOI 10.1186/1476-4598-5-33, PubMed 16952311 -
8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects
Clin Cancer Res, 12 (13), 3961-70
DOI 10.1158/1078-0432.CCR-05-1977, PubMed 16818693 -
Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes
Cell Oncol, 28 (5-6), 315-26
DOI 10.1155/2006/219786, PubMed 17167184 -
Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
J Pathol, 209 (4), 492-500
DOI 10.1002/path.1998, PubMed 16721726 -
Precursor lesions in testis and dysgenetic gonads
Hum Pathol, 37 (6), 773; author reply 774
DOI 10.1016/j.humpath.2006.01.006, PubMed 16733221