Publications

Publications from OUS - Genetics (Lothe)

346 publications found

Publications 2024

1. Majid U, Bergsland CH, Sveen A, Bruun J, Eilertsen IA, Bækkevold ES, Nesbakken A, Yaqub S, Jahnsen FL, Lothe RA (2024)
   The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
   Cell Oncol (Dordr) (in press)
   DOI 10.1007/s13402-024-00926-w, PubMed 38407700
2. Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
   Evolutionary mode and timing of dissemination of high-grade serous carcinomas
   JCI Insight, 9 (3)
   DOI 10.1172/jci.insight.170423, PubMed 38175731
3. Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E (2024)
   The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
   Cell Mol Life Sci, 81 (1), 171
   DOI 10.1007/s00018-024-05165-8, PubMed 38597989

Publications 2023

1. Bogaard M, Skotheim RI, Maltau AV, Kidd SG, Lothe RA, Axcrona K, Axcrona U (2023)
   'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
   Histopathology, 83 (6), 853-869
   DOI 10.1111/his.15012, PubMed 37501635
2. Høland M, Berg KCG, Eilertsen IA, Bjerkehagen B, Kolberg M, Boye K, Lingjærde OC, Guren TK, Mandahl N, van den Berg E, Palmerini E, Smeland S, Picci P, Mertens F, Sveen A, Lothe RA (2023)
   Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
   EBioMedicine, 97, 104829
   DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931
3. Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
   Endocytic trafficking of connexins in cancer pathogenesis
   Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
   DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772

Publications 2022

1. Bergsland CH, Jeanmougin M, Moosavi SH, Svindland A, Bruun J, Nesbakken A, Sveen A, Lothe RA (2022)
   Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer
   Mod Pathol, 35 (9), 1236-1246
   DOI 10.1038/s41379-022-01086-8, PubMed 35484226
2. Carm KT, Johannessen B, Bogaard M, Bakken AC, Maltau AV, Hoff AM, Axcrona U, Axcrona K, Lothe RA, Skotheim RI (2022)
   Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
   Int J Cancer, 152 (5), 945-951
   DOI 10.1002/ijc.34226, PubMed 35880692
3. Grasso C, Popovic M, Isaevska E, Lazzarato F, Fiano V, Zugna D, Pluta J, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Bishop DT, Chanock SJ, Chen C, Cortessis VK, Dalgaard MD, Daneshmand S, Ferlin A, Foresta C, Frone MN, Gamulin M, Gietema JA, Greene MH, Grotmol T, Hamilton RJ et al. (2022)
   Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk
   Cancer Epidemiol Biomarkers Prev, 31 (9), 1769-1779
   DOI 10.1158/1055-9965.EPI-22-0123, PubMed 35700037
4. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
   Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
   J Transl Med, 20 (1), 225
   DOI 10.1186/s12967-022-03432-5, PubMed 35568909
5. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
   Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
   J Transl Med, 20 (1), 317
   DOI 10.1186/s12967-022-03518-0, PubMed 35841045
6. Kidd SG, Bogaard M, Carm KT, Bakken AC, Maltau AMV, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2022)
   In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
   Mol Oncol, 16 (15), 2810-2822
   DOI 10.1002/1878-0261.13225, PubMed 35574900
7. Kryeziu K, Bergsland CH, Guren TK, Sveen A, Lothe RA (2022)
   Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
   Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
   DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193
8. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
   miR-486-5p expression is regulated by DNA methylation in osteosarcoma
   BMC Genomics, 23 (1), 142
   DOI 10.1186/s12864-022-08346-6, PubMed 35172717
9. Strømme JM, Johannessen B, Kidd SG, Bogaard M, Carm KT, Zhang X, Sveen A, Mathelier A, Lothe RA, Axcrona U, Axcrona K, Skotheim RI (2022)
   Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
   Cancer Gene Ther, 29 (8-9), 1276-1284
   DOI 10.1038/s41417-022-00444-7, PubMed 35194199

Publications 2021

1. Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
   Genomic and prognostic heterogeneity among RAS/BRAF^V600E /TP53 co-mutated resectable colorectal liver metastases
   Mol Oncol, 15 (4), 830-845
   DOI 10.1002/1878-0261.12885, PubMed 33325154
2. Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
   E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
   Mol Oncol, 16 (12), 2312-2329
   DOI 10.1002/1878-0261.13159, PubMed 34890102
3. Eide PW, Moosavi SH, Eilertsen IA, Brunsell TH, Langerud J, Berg KCG, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA, Sveen A (2021)
   Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
   NPJ Genom Med, 6 (1), 59
   DOI 10.1038/s41525-021-00223-7, PubMed 34262039
4. Gansmo LB, Sofiyeva N, Bjørnslett M, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
   Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
   Sci Rep, 11 (1), 23463
   DOI 10.1038/s41598-021-02820-z, PubMed 34873230
5. Helwa R, Gansmo LB, Bjørnslett M, Halle MK, Werner HMJ, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
   Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
   Biomarkers, 26 (4), 302-308
   DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
6. Kidd SG, Carm KT, Bogaard M, Olsen LG, Bakken AC, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2021)
   High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
   Neoplasia, 23 (6), 634-641
   DOI 10.1016/j.neo.2021.05.012, PubMed 34107378
7. Kryeziu K, Moosavi SH, Bergsland CH, Guren MG, Eide PW, Totland MZ, Lassen K, Abildgaard A, Nesbakken A, Sveen A, Lothe RA (2021)
   Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
   J Transl Med, 19 (1), 384
   DOI 10.1186/s12967-021-03062-3, PubMed 34496878
8. Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Røsok BI, Brudvik KW, Bjørnbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
   De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
   Genome Med, 13 (1), 143
   DOI 10.1186/s13073-021-00956-1, PubMed 34470666
9. Pluta J, Pyle LC, Nead KT, Wilf R, Li M, Mitra N, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Benitez J, Brown CD, Chanock S, Chen C, Cortessis VK, Ferlin A, Foresta C, Gamulin M, Gietema JA, Grasso C, Greene MH, Grotmol T, Hamilton RJ, Haugen TB, Hauser R et al. (2021)
   Identification of 22 susceptibility loci associated with testicular germ cell tumors
   Nat Commun, 12 (1), 4487
   DOI 10.1038/s41467-021-24334-y, PubMed 34301922
10. Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
    Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
    Acta Oncol, 60 (7), 921-930
    DOI 10.1080/0284186X.2021.1918763, PubMed 33966592
11. Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
    The expressed mutational landscape of microsatellite stable colorectal cancers
    Genome Med, 13 (1), 142
    DOI 10.1186/s13073-021-00955-2, PubMed 34470667
12. Aasebø K, Bruun J, Bergsland CH, Nunes L, Eide GE, Pfeiffer P, Dahl O, Glimelius B, Lothe RA, Sorbye H (2021)
    Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
    Br J Cancer, 126 (1), 48-56
    DOI 10.1038/s41416-021-01586-5, PubMed 34671130

Publications 2020

1. Bergsland CH, Bruun J, Guren MG, Svindland A, Bjørnslett M, Smeby J, Hektoen M, Kolberg M, Domingo E, Pellinen T, Tomlinson I, Kerr D, Church DN, Nesbakken A, Sveen A, Lothe RA (2020)
   Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
   ESMO Open, 5 (6), e001040
   DOI 10.1136/esmoopen-2020-001040, PubMed 33219056
2. Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Røsok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjørnbeth BA, Sveen A, Lothe RA (2020)
   Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
   Clin Cancer Res, 26 (15), 4107-4119
   DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813
3. Flatin BTB, Vedeld HM, Pinto R, Langerud J, Lind GE, Lothe RA, Sveen A, Jeanmougin M (2020)
   Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
   Int J Cancer, 148 (7), 1652-1657
   DOI 10.1002/ijc.33425, PubMed 33284993
4. Hoff AM, Kraggerud SM, Alagaratnam S, Berg KCG, Johannessen B, Høland M, Nilsen G, Lingjærde OC, Andrews PW, Lothe RA, Skotheim RI (2020)
   Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas
   Endocr Relat Cancer, 27 (9), 457-468
   DOI 10.1530/ERC-20-0064, PubMed 32580154
5. Jeanmougin M, Håvik AB, Cekaite L, Brandal P, Sveen A, Meling TR, Ågesen TH, Scheie D, Heim S, Lothe RA, Lind GE (2020)
   Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
   Mol Oncol, 14 (5), 1016-1027
   DOI 10.1002/1878-0261.12668, PubMed 32171051
6. Lopes N, Bergsland C, Bruun J, Bjørnslett M, Vieira AF, Mesquita P, Pinto R, Gomes R, Cavadas B, Bennett E, Pereira L, Lothe RA, Almeida R, David L (2020)
   A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
   Gastric Cancer, 23 (5), 811-823
   DOI 10.1007/s10120-020-01064-6, PubMed 32215766
7. Smeby J, Kryeziu K, Berg KCG, Eilertsen IA, Eide PW, Johannessen B, Guren MG, Nesbakken A, Bruun J, Lothe RA, Sveen A (2020)
   Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
   EBioMedicine, 59, 102923
   DOI 10.1016/j.ebiom.2020.102923, PubMed 32799124
8. Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
   Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
   Blood Adv, 4 (9), 1859-1866
   DOI 10.1182/bloodadvances.2019001325, PubMed 32374878

Publications 2019

1. Berg KCG, Sveen A, Høland M, Alagaratnam S, Berg M, Danielsen SA, Nesbakken A, Søreide K, Lothe RA (2019)
   Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
   Oncogene, 38 (33), 6109-6122
   DOI 10.1038/s41388-019-0868-5, PubMed 31308487
2. Brunsell TH, Cengija V, Sveen A, Bjørnbeth BA, Røsok BI, Brudvik KW, Guren MG, Lothe RA, Abildgaard A, Nesbakken A (2019)
   Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
   Eur J Surg Oncol, 45 (12), 2340-2346
   DOI 10.1016/j.ejso.2019.07.017, PubMed 31350075
3. Brunsell TH, Sveen A, Bjørnbeth BA, Røsok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA (2019)
   High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
   Clin Colorectal Cancer, 19 (1), e26-e47
   DOI 10.1016/j.clcc.2019.09.003, PubMed 31982351
4. Burocziova M, Burdova K, Martinikova AS, Kasparek P, Kleiblova P, Danielsen SA, Borecka M, Jenikova G, Janečková L, Pavel J, Zemankova P, Schneiderova M, Schwarzova L, Ticha I, Sun XF, Jiraskova K, Liska V, Vodickova L, Vodicka P, Sedlacek R, Kleibl Z, Lothe RA, Korinek V, Macurek L (2019)
   Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
   Cell Death Dis, 10 (11), 818
   DOI 10.1038/s41419-019-2057-4, PubMed 31659152
5. Carm KT, Hoff AM, Bakken AC, Axcrona U, Axcrona K, Lothe RA, Skotheim RI, Løvf M (2019)
   Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer
   Sci Rep, 9 (1), 13579
   DOI 10.1038/s41598-019-49964-7, PubMed 31537872
6. Dienstmann R, Villacampa G, Sveen A, Mason MJ, Niedzwiecki D, Nesbakken A, Moreno V, Warren RS, Lothe RA, Guinney J (2019)
   Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer
   Ann Oncol, 30 (10), 1622-1629
   DOI 10.1093/annonc/mdz287, PubMed 31504112
7. Eide PW, Eilertsen IA, Sveen A, Lothe RA (2019)
   Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell-intrinsic properties
   Int J Cancer, 144 (11), 2843-2853
   DOI 10.1002/ijc.31998, PubMed 30447009
8. Eilertsen IA, Moosavi SH, Strømme JM, Nesbakken A, Johannessen B, Lothe RA, Sveen A (2019)
   Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer
   Cancer Lett, 469, 246-255
   DOI 10.1016/j.canlet.2019.10.040, PubMed 31678167
9. Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
   Tumour-infiltrating CD8⁺ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
   Br J Cancer, 121 (6), 474-482
   DOI 10.1038/s41416-019-0540-4, PubMed 31388185
10. Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
    Correction: Tumour-infiltrating CD8⁺ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
    Br J Cancer, 121 (9), 807
    DOI 10.1038/s41416-019-0590-7, PubMed 31548598
11. Joranger P, Nesbakken A, Sorbye H, Hoff G, Oshaug A, Aas E (2019)
    Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach
    Eur J Health Econ, 21 (3), 321-334
    DOI 10.1007/s10198-019-01130-6, PubMed 31707584
12. Kryeziu K, Bruun J, Guren TK, Sveen A, Lothe RA (2019)
    Combination therapies with HSP90 inhibitors against colorectal cancer
    Biochim Biophys Acta Rev Cancer, 1871 (2), 240-247
    DOI 10.1016/j.bbcan.2019.01.002, PubMed 30708039
13. Lopes N, Bergsland CH, Bjørnslett M, Pellinen T, Svindland A, Nesbakken A, Almeida R, Lothe RA, David L, Bruun J (2019)
    Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
    Lab Invest, 100 (1), 120-134
    DOI 10.1038/s41374-019-0336-4, PubMed 31641225
14. Miranda A, Hamilton PT, Zhang AW, Pattnaik S, Becht E, Mezheyeuski A, Bruun J, Micke P, de Reynies A, Nelson BH (2019)
    Cancer stemness, intratumoral heterogeneity, and immune response across cancers
    Proc Natl Acad Sci U S A, 116 (18), 9020-9029
    DOI 10.1073/pnas.1818210116, PubMed 30996127
15. Røsok BI, Høst-Brunsell T, Brudvik KW, Carling U, Dorenberg E, Björnsson B, Lothe RA, Bjørnbeth BA, Sandström P (2019)
    Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
    HPB (Oxford), 21 (8), 1017-1023
    DOI 10.1016/j.hpb.2018.12.003, PubMed 30765198
16. Smeby J, Sveen A, Bergsland CH, Eilertsen IA, Danielsen SA, Eide PW, Hektoen M, Guren MG, Nesbakken A, Bruun J, Lothe RA (2019)
    Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
    ESMO Open, 4 (3), e000523
    DOI 10.1136/esmoopen-2019-000523, PubMed 31321083
17. Smeby J, Sveen A, Eilertsen IA, Danielsen SA, Hoff AM, Eide PW, Johannessen B, Hektoen M, Skotheim RI, Guren MG, Nesbakken A, Lothe RA (2019)
    Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
    Oncogenesis, 8 (6), 35
    DOI 10.1038/s41389-019-0141-3, PubMed 31092812
18. Sveen A, Cremolini C, Dienstmann R (2019)
    Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes
    Ann Oncol, 30 (11), 1682-1685
    DOI 10.1093/annonc/mdz412, PubMed 31868904
19. Sveen A, Kopetz S, Lothe RA (2019)
    Biomarker-guided therapy for colorectal cancer: strength in complexity
    Nat Rev Clin Oncol, 17 (1), 11-32
    DOI 10.1038/s41571-019-0241-1, PubMed 31289352
20. Totland MZ, Rasmussen NL, Knudsen LM, Leithe E (2019)
    Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications
    Cell Mol Life Sci, 77 (4), 573-591
    DOI 10.1007/s00018-019-03285-0, PubMed 31501970
21. Aasen T, Leithe E, Graham SV, Kameritsch P, Mayán MD, Mesnil M, Pogoda K, Tabernero A (2019)
    Connexins in cancer: bridging the gap to the clinic
    Oncogene, 38 (23), 4429-4451
    DOI 10.1038/s41388-019-0741-6, PubMed 30814684

Publications 2018

1. Bruun J, Sveen A, Barros R, Eide PW, Eilertsen I, Kolberg M, Pellinen T, David L, Svindland A, Kallioniemi O, Guren MG, Nesbakken A, Almeida R, Lothe RA (2018)
   Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
   Mol Oncol, 12 (9), 1639-1655
   DOI 10.1002/1878-0261.12347, PubMed 29900672
2. Danielsen HE, Hveem TS, Domingo E, Pradhan M, Kleppe A, Syvertsen RA, Kostolomov I, Nesheim JA, Askautrud HA, Nesbakken A, Lothe RA, Svindland A, Shepherd N, Novelli M, Johnstone E, Tomlinson I, Kerr R, Kerr DJ (2018)
   Prognostic markers for colorectal cancer: estimating ploidy and stroma
   Ann Oncol, 29 (3), 616-623
   DOI 10.1093/annonc/mdx794, PubMed 29293881
3. Eilertsen IA, Sveen A, Strømme JM, Skotheim RI, Nesbakken A, Lothe RA (2018)
   Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
   Int J Cancer, 144 (4), 841-847
   DOI 10.1002/ijc.31809, PubMed 30121958
4. Gleditsch D, Wexels WA, Nesbakken A (2018)
   Surgical options and trends in treating rectal prolapse: long-term results in a 19-year follow-up study
   Langenbecks Arch Surg, 403 (8), 991-998
   DOI 10.1007/s00423-018-1728-4, PubMed 30415286
5. Høland M, Kolberg M, Danielsen SA, Bjerkehagen B, Eilertsen IA, Hektoen M, Mandahl N, van den Berg E, Smeland S, Mertens F, Sundby Hall K, Picci P, Sveen A, Lothe RA (2018)
   Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53
   Mod Pathol, 31 (11), 1694-1707
   DOI 10.1038/s41379-018-0074-y, PubMed 29946184
6. Kleppe A, Albregtsen F, Vlatkovic L, Pradhan M, Nielsen B, Hveem TS, Askautrud HA, Kristensen GB, Nesbakken A, Trovik J, Wæhre H, Tomlinson I, Shepherd NA, Novelli M, Kerr DJ, Danielsen HE (2018)
   Chromatin organisation and cancer prognosis: a pan-cancer study
   Lancet Oncol, 19 (3), 356-369
   DOI 10.1016/S1470-2045(17)30899-9, PubMed 29402700
7. Lønning PE, Berge EO, Bjørnslett M, Minsaas L, Chrisanthar R, Høberg-Vetti H, Dulary C, Busato F, Bjørneklett S, Eriksen C, Kopperud R, Axcrona U, Davidson B, Bjørge L, Evans G, Howell A, Salvesen HB, Janszky I, Hveem K, Romundstad PR, Vatten LJ, Tost J, Dørum A, Knappskog S (2018)
   White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk
   Ann Intern Med, 168 (5), 326-334
   DOI 10.7326/M17-0101, PubMed 29335712
8. Løvf M, Zhao S, Axcrona U, Johannessen B, Bakken AC, Carm KT, Hoff AM, Myklebost O, Meza-Zepeda LA, Lie AK, Axcrona K, Lothe RA, Skotheim RI (2018)
   Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
   Eur Urol, 75 (3), 498-505
   DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068
9. Mezheyeuski A, Bergsland CH, Backman M, Djureinovic D, Sjöblom T, Bruun J, Micke P (2018)
   Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients
   J Pathol, 244 (4), 421-431
   DOI 10.1002/path.5026, PubMed 29282718
10. Oltedal S, Kørner H, Aasprong OG, Hussain I, Tjensvoll K, Smaaland R, Søreide JA, Søreide K, Lothe RA, Heikkilä R, Gilje B, Nordgård O (2018)
    The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer
    Transl Oncol, 11 (2), 436-443
    DOI 10.1016/j.tranon.2018.01.015, PubMed 29475140
11. Ommundsen N, Nesbakken A, Wyller TB, Skovlund E, Bakka AO, Jordhøy MS, Rostoft S (2018)
    Post-discharge complications in frail older patients after surgery for colorectal cancer
    Eur J Surg Oncol, 44 (10), 1542-1547
    DOI 10.1016/j.ejso.2018.06.024, PubMed 30037638
12. Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhøy MS, Skovlund E, Rostoft S (2018)
    Preoperative geriatric assessment and tailored interventions in frail older patients with colorectal cancer: a randomized controlled trial
    Colorectal Dis, 20 (1), 16-25
    DOI 10.1111/codi.13785, PubMed 28649755
13. Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhøy MS, Skovlund E, Rostoft S (2018)
    Reply to Lawday et al
    Colorectal Dis, 20 (4), 350-351
    DOI 10.1111/codi.14059, PubMed 29502337
14. Pharo HD, Andresen K, Berg KCG, Lothe RA, Jeanmougin M, Lind GE (2018)
    A robust internal control for high-precision DNA methylation analyses by droplet digital PCR
    Clin Epigenetics, 10, 24
    DOI 10.1186/s13148-018-0456-5, PubMed 29484034
15. Pinto D, Pinto C, Guerra J, Pinheiro M, Santos R, Vedeld HM, Yohannes Z, Peixoto A, Santos C, Pinto P, Lopes P, Lothe R, Lind GE, Henrique R, Teixeira MR (2018)
    Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation
    Cancer Med, 7 (2), 433-444
    DOI 10.1002/cam4.1285, PubMed 29341452
16. Smeby J, Sveen A, Merok MA, Danielsen SA, Eilertsen IA, Guren MG, Dienstmann R, Nesbakken A, Lothe RA (2018)
    CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer
    Ann Oncol, 29 (5), 1227-1234
    DOI 10.1093/annonc/mdy085, PubMed 29518181
17. Vedeld HM, Nesbakken A, Lothe RA, Lind GE (2018)
    Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer
    Clin Epigenetics, 10, 70
    DOI 10.1186/s13148-018-0503-2, PubMed 29854011

Publications 2017

1. Berg KCG, Eide PW, Eilertsen IA, Johannessen B, Bruun J, Danielsen SA, Bjørnslett M, Meza-Zepeda LA, Eknæs M, Lind GE, Myklebost O, Skotheim RI, Sveen A, Lothe RA (2017)
   Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
   Mol Cancer, 16 (1), 116
   DOI 10.1186/s12943-017-0691-y, PubMed 28683746
2. Dienstmann R, Mason MJ, Sinicrope FA, Phipps AI, Tejpar S, Nesbakken A, Danielsen SA, Sveen A, Buchanan DD, Clendenning M, Rosty C, Bot B, Alberts SR, Milburn Jessup J, Lothe RA, Delorenzi M, Newcomb PA, Sargent D, Guinney J (2017)
   Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
   Ann Oncol, 28 (5), 1023-1031
   DOI 10.1093/annonc/mdx052, PubMed 28453697
3. Dukic AR, Haugen LH, Pidoux G, Leithe E, Bakke O, Taskén K (2017)
   A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells
   Cell Signal, 32, 1-11
   DOI 10.1016/j.cellsig.2017.01.008, PubMed 28077322
4. Eide PW, Bruun J, Lothe RA, Sveen A (2017)
   CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models
   Sci Rep, 7 (1), 16618
   DOI 10.1038/s41598-017-16747-x, PubMed 29192179
5. Gansmo LB, Bjørnslett M, Halle MK, Salvesen HB, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2017)
   MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
   BMC Cancer, 17 (1), 97
   DOI 10.1186/s12885-017-3094-y, PubMed 28158999
6. Kolberg M, Bruun J, Murumägi A, Mpindi JP, Bergsland CH, Høland M, Eilertsen IA, Danielsen SA, Kallioniemi O, Lothe RA (2017)
   Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
   Mol Oncol, 11 (9), 1156-1171
   DOI 10.1002/1878-0261.12086, PubMed 28556483
7. Labori KJ, Guren MG, Brudvik KW, Røsok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjørnbeth BA (2017)
   Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
   Colorectal Dis, 19 (8), 731-738
   DOI 10.1111/codi.13622, PubMed 28181384
8. Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K (2017)
   C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
   PLoS One, 12 (7), e0182030
   DOI 10.1371/journal.pone.0182030, PubMed 28759630
9. Leithe E, Mesnil M, Aasen T (2017)
   The connexin 43 C-terminus: A tail of many tales
   Biochim Biophys Acta Biomembr, 1860 (1), 48-64
   DOI 10.1016/j.bbamem.2017.05.008, PubMed 28526583
10. Lind GE, Guriby M, Ahlquist T, Hussain I, Jeanmougin M, Søreide K, Kørner H, Lothe RA, Nordgård O (2017)
    Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
    Clin Epigenetics, 9, 97
    DOI 10.1186/s13148-017-0397-4, PubMed 28878843
11. Mesnil M, Aasen T, Boucher J, Chépied A, Cronier L, Defamie N, Kameritsch P, Laird DW, Lampe PD, Lathia JD, Leithe E, Mehta PP, Monvoisin A, Pogoda K, Sin WC, Tabernero A, Yamasaki H, Yeh ES, Dagli MLZ, Naus CC (2017)
    An update on minding the gap in cancer
    Biochim Biophys Acta Biomembr, 1860 (1), 237-243
    DOI 10.1016/j.bbamem.2017.06.015, PubMed 28655619
12. Solheim O, Førsund M, Tropé CG, Kraggerud SM, Nesland JM, Davidson B (2017)
    Epithelial-mesenchymal transition markers in malignant ovarian germ cell tumors
    APMIS, 125 (9), 781-786
    DOI 10.1111/apm.12715, PubMed 28585395
13. Sveen A, Bruun J, Eide PW, Eilertsen IA, Ramirez L, Murumägi A, Arjama M, Danielsen SA, Kryeziu K, Elez E, Tabernero J, Guinney J, Palmer HG, Nesbakken A, Kallioniemi O, Dienstmann R, Lothe RA (2017)
    Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
    Clin Cancer Res, 24 (4), 794-806
    DOI 10.1158/1078-0432.CCR-17-1234, PubMed 29242316
14. Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA (2017)
    Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
    Genome Med, 9 (1), 46
    DOI 10.1186/s13073-017-0434-0, PubMed 28539123
15. Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
    The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
    J Cell Sci, 130 (17), 2867-2882
    DOI 10.1242/jcs.202408, PubMed 28733455
16. Vedeld HM, Merok M, Jeanmougin M, Danielsen SA, Honne H, Presthus GK, Svindland A, Sjo OH, Hektoen M, Eknaes M, Nesbakken A, Lothe RA, Lind GE (2017)
    CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers
    Int J Cancer, 141 (5), 967-976
    DOI 10.1002/ijc.30796, PubMed 28542846

Publications 2016

1. Boye K, Jacob H, Frikstad KA, Nesland JM, Maelandsmo GM, Dahl O, Nesbakken A, Flatmark K (2016)
   Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
   Cancer Med, 5 (8), 1840-9
   DOI 10.1002/cam4.766, PubMed 27273130
2. Cekaite L, Eide PW, Lind GE, Skotheim RI, Lothe RA (2016)
   MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer
   Oncotarget, 7 (6), 6476-505
   DOI 10.18632/oncotarget.6390, PubMed 26623728
3. Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Castellví-Bel S, Muñoz J, Epicolon consortium, de Bruyn M, Nijman HW et al. (2016)
   Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
   Lancet Gastroenterol Hepatol, 1 (3), 207-216
   DOI 10.1016/S2468-1253(16)30014-0, PubMed 28404093
4. Fykerud TA, Knudsen LM, Totland MZ, Sørensen V, Dahal-Koirala S, Lothe RA, Brech A, Leithe E (2016)
   Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
   Cell Cycle, 15 (21), 2943-2957
   DOI 10.1080/15384101.2016.1231280, PubMed 27625181
5. Gansmo LB, Bjørnslett M, Halle MK, Salvesen HB, Dørum A, Birkeland E, Hveem K, Romundstad P, Vatten L, Lønning PE, Knappskog S (2016)
   The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer
   Tumour Biol, 37 (8), 10697-702
   DOI 10.1007/s13277-016-4940-2, PubMed 26867771
6. Gleditsch D, Søreide OK, Nesbakken A (2016)
   Managing Malignant Colorectal Obstruction with Self-Expanding Stents. A Closer Look at Bowel Perforations and Failed Procedures
   J Gastrointest Surg, 20 (9), 1643-9
   DOI 10.1007/s11605-016-3186-z, PubMed 27342437
7. Leithe E (2016)
   Regulation of connexins by the ubiquitin system: Implications for intercellular communication and cancer
   Biochim Biophys Acta, 1865 (2), 133-46
   DOI 10.1016/j.bbcan.2016.02.001, PubMed 26855059
8. Lorenz S, Barøy T, Sun J, Nome T, Vodák D, Bryne JC, Håkelien AM, Fernandez-Cuesta L, Möhlendick B, Rieder H, Szuhai K, Zaikova O, Ahlquist TC, Thomassen GO, Skotheim RI, Lothe RA, Tarpey PS, Campbell P, Flanagan A, Myklebost O, Meza-Zepeda LA (2016)
   Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations
   Oncotarget, 7 (5), 5273-88
   DOI 10.18632/oncotarget.6567, PubMed 26672768
9. Moen LV, Ramberg H, Zhao S, Grytli HH, Sveen A, Berge V, Skotheim RI, Taskén KA, Skålhegg BS (2016)
   Observed correlation between the expression levels of catalytic subunit, Cβ2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness
   Urol Oncol, 35 (3), 111.e1-111.e8
   DOI 10.1016/j.urolonc.2016.10.002, PubMed 27838142
10. Ramalho-Carvalho J, Martins JB, Cekaite L, Sveen A, Torres-Ferreira J, Graça I, Costa-Pinheiro P, Eilertsen IA, Antunes L, Oliveira J, Lothe RA, Henrique R, Jerónimo C (2016)
    Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1
    Cancer Lett, 385, 150-159
    DOI 10.1016/j.canlet.2016.10.028, PubMed 27984115
11. Rønning B, Wyller TB, Nesbakken A, Skovlund E, Jordhøy MS, Bakka A, Rostoft S (2016)
    Quality of life in older and frail patients after surgery for colorectal cancer-A follow-up study
    J Geriatr Oncol, 7 (3), 195-200
    DOI 10.1016/j.jgo.2016.03.002, PubMed 27067579
12. Stornes T, Wibe A, Nesbakken A, Myklebust TÅ, Endreseth BH (2016)
    National Early Rectal Cancer Treatment Revisited
    Dis Colon Rectum, 59 (7), 623-9
    DOI 10.1097/DCR.0000000000000591, PubMed 27270514
13. Sveen A, Løes IM, Alagaratnam S, Nilsen G, Høland M, Lingjærde OC, Sorbye H, Berg KC, Horn A, Angelsen JH, Knappskog S, Lønning PE, Lothe RA (2016)
    Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection
    PLoS Genet, 12 (7), e1006225
    DOI 10.1371/journal.pgen.1006225, PubMed 27472274

Publications 2015

1. Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KE, Paulsen V, Foss A, Mathisen Ø, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
   Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
   Hepatology, 61 (5), 1651-9
   DOI 10.1002/hep.27707, PubMed 25644509
2. Bjørnslett M, Dahl AA, Sørebø Ø, Dørum A (2015)
   Psychological distress related to BRCA testing in ovarian cancer patients
   Fam Cancer, 14 (4), 495-504
   DOI 10.1007/s10689-015-9811-2, PubMed 25980896
3. Brabrand S, Johannessen B, Axcrona U, Kraggerud SM, Berg KG, Bakken AC, Bruun J, Fosså SD, Lothe RA, Lehne G, Skotheim RI (2015)
   Exome sequencing of bilateral testicular germ cell tumors suggests independent development lineages
   Neoplasia, 17 (2), 167-74
   DOI 10.1016/j.neo.2014.12.005, PubMed 25748235
4. Bruun J, Kolberg M, Ahlquist TC, Røyrvik EC, Nome T, Leithe E, Lind GE, Merok MA, Rognum TO, Bjørkøy G, Johansen T, Lindblom A, Sun XF, Svindland A, Liestøl K, Nesbakken A, Skotheim RI, Lothe RA (2015)
   Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer
   Clin Cancer Res, 21 (16), 3759-70
   DOI 10.1158/1078-0432.CCR-14-3294, PubMed 25910952
5. Guren MG, Kørner H, Pfeffer F, Myklebust TÅ, Eriksen MT, Edna TH, Larsen SG, Knudsen KO, Nesbakken A, Wasmuth HH, Vonen B, Hofsli E, Færden AE, Brændengen M, Dahl O, Steigen SE, Johansen MJ, Lindsetmo RO, Drolsum A, Tollåli G, Dørum LM, Møller B, Wibe A (2015)
   Nationwide improvement of rectal cancer treatment outcomes in Norway, 1993-2010
   Acta Oncol, 54 (10), 1714-22
   DOI 10.3109/0284186X.2015.1034876, PubMed 25924970
6. Hoff AM, Alagaratnam S, Zhao S, Bruun J, Andrews PW, Lothe RA, Skotheim RI (2015)
   Identification of Novel Fusion Genes in Testicular Germ Cell Tumors
   Cancer Res, 76 (1), 108-16
   DOI 10.1158/0008-5472.CAN-15-1790, PubMed 26659575
7. Hoff AM, Johannessen B, Alagaratnam S, Zhao S, Nome T, Løvf M, Bakken AC, Hektoen M, Sveen A, Lothe RA, Skotheim RI (2015)
   Novel RNA variants in colorectal cancers
   Oncotarget, 6 (34), 36587-602
   DOI 10.18632/oncotarget.5500, PubMed 26474385
8. Johannessen B, Sveen A, Skotheim RI (2015)
   TIN: An R Package for Transcriptome Instability Analysis
   Cancer Inform, 14, 109-12
   DOI 10.4137/CIN.S31363, PubMed 26448683
9. Kolberg M, Høland M, Lind GE, Ågesen TH, Skotheim RI, Hall KS, Mandahl N, Smeland S, Mertens F, Davidson B, Lothe RA (2015)
   Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection
   Mol Oncol, 9 (6), 1129-39
   DOI 10.1016/j.molonc.2015.02.005, PubMed 25769404
10. Mesquita D, Barros-Silva JD, Santos J, Skotheim RI, Lothe RA, Paulo P, Teixeira MR (2015)
    Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts
    Oncotarget, 6 (7), 5217-36
    DOI 10.18632/oncotarget.2847, PubMed 25595908
11. Seglen PO, Luhr M, Mills IG, Sætre F, Szalai P, Engedal N (2015)
    Macroautophagic cargo sequestration assays
    Methods, 75, 25-36
    DOI 10.1016/j.ymeth.2014.12.021, PubMed 25576638
12. Sveen A, Kilpinen S, Ruusulehto A, Lothe RA, Skotheim RI (2015)
    Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes
    Oncogene, 35 (19), 2413-27
    DOI 10.1038/onc.2015.318, PubMed 26300000

Publications 2014

1. Almeida M, Costa VL, Costa NR, Ramalho-Carvalho J, Baptista T, Ribeiro FR, Paulo P, Teixeira MR, Oliveira J, Lothe RA, Lind GE, Henrique R, Jerónimo C (2014)
   Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential
   J Cell Mol Med, 18 (11), 2287-97
   DOI 10.1111/jcmm.12394, PubMed 25211630
2. Bruun J, Kolberg M, Nesland JM, Svindland A, Nesbakken A, Lothe RA (2014)
   Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
   Front Oncol, 4, 118
   DOI 10.3389/fonc.2014.00118, PubMed 24904831
3. Danielsen SA, Eide PW, Nesbakken A, Guren T, Leithe E, Lothe RA (2014)
   Portrait of the PI3K/AKT pathway in colorectal cancer
   Biochim Biophys Acta, 1855 (1), 104-21
   DOI 10.1016/j.bbcan.2014.09.008, PubMed 25450577
4. Danielsen SA, Lind GE, Kolberg M, Høland M, Bjerkehagen B, Sundby Hall K, van den Berg E, Mertens F, Smeland S, Picci P, Lothe RA (2014)
   Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis
   Neuro Oncol, 17 (1), 63-9
   DOI 10.1093/neuonc/nou140, PubMed 25038505
5. Hveem TS, Merok MA, Pretorius ME, Novelli M, Bævre MS, Sjo OH, Clinch N, Liestøl K, Svindland A, Lothe RA, Nesbakken A, Danielsen HE (2014)
   Prognostic impact of genomic instability in colorectal cancer
   Br J Cancer, 110 (8), 2159-64
   DOI 10.1038/bjc.2014.133, PubMed 24642618
6. Joranger P, Nesbakken A, Hoff G, Sorbye H, Oshaug A, Aas E (2014)
   Modeling and validating the cost and clinical pathway of colorectal cancer
   Med Decis Making, 35 (2), 255-65
   DOI 10.1177/0272989X14544749, PubMed 25073464
7. Løvf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2014)
   A novel transcript, VNN1-AB, as a biomarker for colorectal cancer
   Int J Cancer, 135 (9), 2077-84
   DOI 10.1002/ijc.28855, PubMed 24687856
8. Sirnes S, Lind GE, Bruun J, Fykerud TA, Mesnil M, Lothe RA, Rivedal E, Kolberg M, Leithe E (2014)
   Connexins in colorectal cancer pathogenesis
   Int J Cancer, 137 (1), 1-11
   DOI 10.1002/ijc.28911, PubMed 24752574
9. Smebye ML, Sveen A, Haugom L, Davidson B, Tropé CG, Lothe RA, Heim S, Skotheim RI, Micci F (2014)
   Chromosome 19 rearrangements in ovarian carcinomas: zinc finger genes are particularly targeted
   Genes Chromosomes Cancer, 53 (7), 558-67
   DOI 10.1002/gcc.22166, PubMed 24634323
10. Sveen A, Johannessen B, Teixeira MR, Lothe RA, Skotheim RI (2014)
    Transcriptome instability as a molecular pan-cancer characteristic of carcinomas
    BMC Genomics, 15 (1), 672
    DOI 10.1186/1471-2164-15-672, PubMed 25109687
11. Søndenaa K, Quirke P, Hohenberger W, Sugihara K, Kobayashi H, Kessler H, Brown G, Tudyka V, D'Hoore A, Kennedy RH, West NP, Kim SH, Heald R, Storli KE, Nesbakken A, Moran B (2014)
    The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference
    Int J Colorectal Dis, 29 (4), 419-28
    DOI 10.1007/s00384-013-1818-2, PubMed 24477788
12. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
    Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
    Methods Mol Biol, 1105, 315-24
    DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239
13. Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
    The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
    Int J Cancer, 136 (4), 844-53
    DOI 10.1002/ijc.29039, PubMed 24948044
14. Vedeld HM, Skotheim RI, Lothe RA, Lind GE (2014)
    The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer
    Epigenetics, 9 (3), 346-50
    DOI 10.4161/epi.27582, PubMed 24384857

Publications 2013

1. Ahmed D, Eide PW, Eilertsen IA, Danielsen SA, Eknæs M, Hektoen M, Lind GE, Lothe RA (2013)
   Epigenetic and genetic features of 24 colon cancer cell lines
   Oncogenesis, 2 (9), e71
   DOI 10.1038/oncsis.2013.35, PubMed 24042735
2. Alagaratnam S, Harrison N, Bakken AC, Hoff AM, Jones M, Sveen A, Moore HD, Andrews PW, Lothe RA, Skotheim RI (2013)
   Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
   Stem Cells Dev, 22 (7), 1136-46
   DOI 10.1089/scd.2012.0369, PubMed 23137282
3. Avery S, Hirst AJ, Baker D, Lim CY, Alagaratnam S, Skotheim RI, Lothe RA, Pera MF, Colman A, Robson P, Andrews PW, Knowles BB (2013)
   BCL-XL mediates the strong selective advantage of a 20q11.21 amplification commonly found in human embryonic stem cell cultures
   Stem Cell Reports, 1 (5), 379-86
   DOI 10.1016/j.stemcr.2013.10.005, PubMed 24286026
4. Barros-Silva JD, Paulo P, Bakken AC, Cerveira N, Løvf M, Henrique R, Jerónimo C, Lothe RA, Skotheim RI, Teixeira MR (2013)
   Novel 5' fusion partners of ETV1 and ETV4 in prostate cancer
   Neoplasia, 15 (7), 720-6
   DOI 10.1593/neo.13232, PubMed 23814484
5. Berg M, Guriby M, Nordgård O, Nedrebø BS, Ahlquist TC, Smaaland R, Oltedal S, Søreide JA, Kørner H, Lothe RA, Søreide K (2013)
   Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I-III colon cancers
   Mol Med, 19 (1), 286-93
   DOI 10.2119/molmed.2013.00049, PubMed 23979710
6. Bethge N, Honne H, Hilden V, Trøen G, Eknæs M, Liestøl K, Holte H, Delabie J, Smeland EB, Lind GE (2013)
   Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma
   PLoS One, 8 (11), e79602
   DOI 10.1371/journal.pone.0079602, PubMed 24260260
7. Bethge N, Lothe RA, Honne H, Andresen K, Trøen G, Eknæs M, Liestøl K, Holte H, Delabie J, Smeland EB, Lind GE (2013)
   Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
   Epigenetics, 9 (3), 428-36
   DOI 10.4161/epi.27554, PubMed 24362313
8. Chung CC, Kanetsky PA, Wang Z, Hildebrandt MA, Koster R, Skotheim RI, Kratz CP, Turnbull C, Cortessis VK, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Jacobs KB, Korde LA, Kraggerud SM, Lothe RA, Loud JT, Rahman N, Skinner EC, Thomas DC, Wu X, Yeager M, Schumacher FR et al. (2013)
   Meta-analysis identifies four new loci associated with testicular germ cell tumor
   Nat Genet, 45 (6), 680-5
   DOI 10.1038/ng.2634, PubMed 23666239
9. Håvik AB, Lind GE, Honne H, Meling TR, Scheie D, Hall KS, van den Berg E, Mertens F, Picci P, Lothe RA, Heim S, Brandal P (2013)
   Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors
   Neuro Oncol, 16 (2), 320-2
   DOI 10.1093/neuonc/not230, PubMed 24311631
10. Kraggerud SM, Hoei-Hansen CE, Alagaratnam S, Skotheim RI, Abeler VM, Rajpert-De Meyts E, Lothe RA (2013)
    Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis
    Endocr Rev, 34 (3), 339-76
    DOI 10.1210/er.2012-1045, PubMed 23575763
11. Løvf M, Thomassen GO, Mertens F, Cerveira N, Teixeira MR, Lothe RA, Skotheim RI (2013)
    Assessment of fusion gene status in sarcomas using a custom made fusion gene microarray
    PLoS One, 8 (8), e70649
    DOI 10.1371/journal.pone.0070649, PubMed 23967081
12. Mesquita B, Lopes P, Rodrigues A, Pereira D, Afonso M, Leal C, Henrique R, Lind GE, Jerónimo C, Lothe RA, Teixeira MR (2013)
    Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes
    Breast Cancer Res Treat, 138 (1), 37-45
    DOI 10.1007/s10549-013-2408-2, PubMed 23329352
13. Nome T, Thomassen GO, Bruun J, Ahlquist T, Bakken AC, Hoff AM, Rognum T, Nesbakken A, Lorenz S, Sun J, Barros-Silva JD, Lind GE, Myklebost O, Teixeira MR, Meza-Zepeda LA, Lothe RA, Skotheim RI (2013)
    Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing
    Transl Oncol, 6 (5), 546-53
    DOI 10.1593/tlo.13457, PubMed 24151535
14. Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, Kolonel LN, Loud JT, Korde LA, Le Marchand L, Lewinger JP, Lothe RA, Pike MC, Rahman N, Rubertone MV, Schwartz SM et al. (2013)
    Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23
    Hum Mol Genet, 22 (13), 2748-53
    DOI 10.1093/hmg/ddt109, PubMed 23462292

Publications 2012

1. Agesen TH, Sveen A, Merok MA, Lind GE, Nesbakken A, Skotheim RI, Lothe RA (2012)
   ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
   Gut, 61 (11), 1560-7
   DOI 10.1136/gutjnl-2011-301179, PubMed 22213796
2. Ahmed D, Danielsen SA, Aagesen TH, Bretthauer M, Thiis-Evensen E, Hoff G, Rognum TO, Nesbakken A, Lothe RA, Lind GE (2012)
   A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
   Clin Transl Gastroenterol, 3 (12), e27
   DOI 10.1038/ctg.2012.21, PubMed 23324654
3. Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
   Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
   Epigenetics, 7 (11), 1249-57
   DOI 10.4161/epi.22191, PubMed 22983262
4. Camões MJ, Paulo P, Ribeiro FR, Barros-Silva JD, Almeida M, Costa VL, Cerveira N, Skotheim RI, Lothe RA, Henrique R, Jerónimo C, Teixeira MR (2012)
   Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma
   PLoS One, 7 (11), e49819
   DOI 10.1371/journal.pone.0049819, PubMed 23185447
5. Cekaite L, Rantala JK, Bruun J, Guriby M, Agesen TH, Danielsen SA, Lind GE, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2012)
   MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
   Neoplasia, 14 (9), 868-79
   DOI 10.1593/neo.121094, PubMed 23019418
6. Celestino R, Sigstad E, Løvf M, Thomassen GO, Grøholt KK, Jørgensen LH, Berner A, Castro P, Lothe RA, Bjøro T, Sobrinho-Simões M, Soares P, Skotheim RI (2012)
   Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes
   Genes Chromosomes Cancer, 51 (12), 1154-64
   DOI 10.1002/gcc.22003, PubMed 22961909
7. Eide PW, Cekaite L, Danielsen SA, Eilertsen IA, Kjenseth A, Fykerud TA, Ågesen TH, Bruun J, Rivedal E, Lothe RA, Leithe E (2012)
   NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
   Cell Signal, 25 (1), 12-8
   DOI 10.1016/j.cellsig.2012.08.012, PubMed 22974840
8. Fykerud TA, Kjenseth A, Schink KO, Sirnes S, Bruun J, Omori Y, Brech A, Rivedal E, Leithe E (2012)
   Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
   J Cell Sci, 125 (Pt 17), 3966-76
   DOI 10.1242/jcs.093500, PubMed 22623726
9. Håvik AB, Brandal P, Honne H, Dahlback HS, Scheie D, Hektoen M, Meling TR, Helseth E, Heim S, Lothe RA, Lind GE (2012)
   MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
   J Transl Med, 10, 36
   DOI 10.1186/1479-5876-10-36, PubMed 22390413
10. Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E (2012)
    The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation
    J Biol Chem, 287 (19), 15851-61
    DOI 10.1074/jbc.M111.281832, PubMed 22411987
11. Kolberg M, Høland M, Agesen TH, Brekke HR, Liestøl K, Hall KS, Mertens F, Picci P, Smeland S, Lothe RA (2012)
    Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1
    Neuro Oncol, 15 (2), 135-47
    DOI 10.1093/neuonc/nos287, PubMed 23161774
12. Kristjansson SR, Ronning B, Hurria A, Skovlund E, Jordhoy MS, Nesbakken A, Wyller TB (2012)
    A comparison of two pre-operative frailty measures in older surgical cancer patients
    J. Geriatr. Oncol., 3 (1), 1-7
    DOI 10.1016/j.jgo.2011.09.002
13. Lind GE, Ahmed D, Lothe RA (2012)
    Vimentin in upper gastrointestinal pathologies--letter
    Cancer Epidemiol Biomarkers Prev, 21 (10), 1889; author reply 1890
    DOI 10.1158/1055-9965.EPI-12-0894, PubMed 22929079
14. Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
    Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
    EMBO Rep, 14 (1), 10-1
    DOI 10.1038/embor.2012.188, PubMed 23229585
15. Matheu A, Collado M, Wise C, Manterola L, Cekaite L, Tye AJ, Canamero M, Bujanda L, Schedl A, Cheah KS, Skotheim RI, Lothe RA, López de Munain A, Briscoe J, Serrano M, Lovell-Badge R (2012)
    Oncogenicity of the developmental transcription factor Sox9
    Cancer Res, 72 (5), 1301-15
    DOI 10.1158/0008-5472.CAN-11-3660, PubMed 22246670
16. Merok MA, Ahlquist T, Røyrvik EC, Tufteland KF, Hektoen M, Sjo OH, Mala T, Svindland A, Lothe RA, Nesbakken A (2012)
    Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
    Ann Oncol, 24 (5), 1274-82
    DOI 10.1093/annonc/mds614, PubMed 23235802
17. Nordgård O, Oltedal S, Aasprong OG, Søreide JA, Søreide K, Tjensvoll K, Gilje B, Heikkilä R, Guriby M, Lothe RA, Smaaland R, Kørner H (2012)
    Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients
    Ann Surg Oncol, 19 (12), 3719-26
    DOI 10.1245/s10434-012-2454-8, PubMed 22752373
18. Nyquist KB, Panagopoulos I, Thorsen J, Haugom L, Gorunova L, Bjerkehagen B, Fosså A, Guriby M, Nome T, Lothe RA, Skotheim RI, Heim S, Micci F (2012)
    Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
    PLoS One, 7 (11), e49705
    DOI 10.1371/journal.pone.0049705, PubMed 23185413
19. Paulo P, Ribeiro FR, Santos J, Mesquita D, Almeida M, Barros-Silva JD, Itkonen H, Henrique R, Jerónimo C, Sveen A, Mills IG, Skotheim RI, Lothe RA, Teixeira MR (2012)
    Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements
    Neoplasia, 14 (7), 600-11
    DOI 10.1593/neo.12600, PubMed 22904677
20. Sjo OH, Merok MA, Svindland A, Nesbakken A (2012)
    Prognostic impact of lymph node harvest and lymph node ratio in patients with colon cancer
    Dis Colon Rectum, 55 (3), 307-15
    DOI 10.1097/DCR.0b013e3182423f62, PubMed 22469798
21. Sveen A, Bakken AC, Ågesen TH, Lind GE, Nesbakken A, Nordgård O, Brackmann S, Rognum TO, Lothe RA, Skotheim RI (2012)
    The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
    Int J Cancer, 131 (6), 1479-85
    DOI 10.1002/ijc.27399, PubMed 22173985
22. Sveen A, Ågesen TH, Nesbakken A, Meling GI, Rognum TO, Liestøl K, Skotheim RI, Lothe RA (2012)
    ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
    Clin Cancer Res, 18 (21), 6001-10
    DOI 10.1158/1078-0432.CCR-11-3302, PubMed 22991413

Publications 2011

1. Ahmed D, Lothe RA, Rivedal E, Lind GE (2011)
   Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors
   Endocr Relat Cancer, 18 (6), C31-4
   DOI 10.1530/ERC-11-0204, PubMed 21868474
2. Alagaratnam S, Lind GE, Kraggerud SM, Lothe RA, Skotheim RI (2011)
   The testicular germ cell tumour transcriptome
   Int J Androl, 34 (4 Pt 2), e133-50; discussion e150-1
   DOI 10.1111/j.1365-2605.2011.01169.x, PubMed 21651573
3. Costa VL, Henrique R, Danielsen SA, Eknaes M, Patrício P, Morais A, Oliveira J, Lothe RA, Teixeira MR, Lind GE, Jerónimo C (2011)
   TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers
   Epigenetics, 6 (9), 1120-30
   DOI 10.4161/epi.6.9.16376, PubMed 21847011
4. Danielsen SA, Cekaite L, Ågesen TH, Sveen A, Nesbakken A, Thiis-Evensen E, Skotheim RI, Lind GE, Lothe RA (2011)
   Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
   PLoS One, 6 (9), e24419
   DOI 10.1371/journal.pone.0024419, PubMed 21909432
5. Hølmebakk T, Solbakken A, Mala T, Nesbakken A (2011)
   Clinical prediction of survival by surgeons for patients with incurable abdominal malignancy
   Eur J Surg Oncol, 37 (7), 571-5
   DOI 10.1016/j.ejso.2011.02.009, PubMed 21444178
6. Leithe E, Sirnes S, Fykerud T, Kjenseth A, Rivedal E (2011)
   Endocytosis and post-endocytic sorting of connexins
   Biochim Biophys Acta, 1818 (8), 1870-9
   DOI 10.1016/j.bbamem.2011.09.029, PubMed 21996040
7. Lind GE, Danielsen SA, Ahlquist T, Merok MA, Andresen K, Skotheim RI, Hektoen M, Rognum TO, Meling GI, Hoff G, Bretthauer M, Thiis-Evensen E, Nesbakken A, Lothe RA (2011)
   Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
   Mol Cancer, 10, 85
   DOI 10.1186/1476-4598-10-85, PubMed 21777459
8. Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
   SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
   Oncogene, 30 (37), 3967-78
   DOI 10.1038/onc.2011.109, PubMed 21499309
9. Løvf M, Thomassen GO, Bakken AC, Celestino R, Fioretos T, Lind GE, Lothe RA, Skotheim RI (2011)
   Fusion gene microarray reveals cancer type-specificity among fusion genes
   Genes Chromosomes Cancer, 50 (5), 348-57
   DOI 10.1002/gcc.20860, PubMed 21305644
10. Ohnstad HO, Paulsen EB, Noordhuis P, Berg M, Lothe RA, Vassilev LT, Myklebost O (2011)
    MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
    BMC Cancer, 11, 211:1-11
    DOI 10.1186/1471-2407-11-211, PubMed 21624110
11. Paulo P, Barros-Silva JD, Ribeiro FR, Ramalho-Carvalho J, Jerónimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR (2011)
    FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer
    Genes Chromosomes Cancer, 51 (3), 240-9
    DOI 10.1002/gcc.20948, PubMed 22081504
12. Ribeiro FR, Paulo P, Costa VL, Barros-Silva JD, Ramalho-Carvalho J, Jerónimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR (2011)
    Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene
    PLoS One, 6 (7), e22317
    DOI 10.1371/journal.pone.0022317, PubMed 21814574
13. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2011)
    Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
    Int J Cancer, 131 (3), 570-81
    DOI 10.1002/ijc.26392, PubMed 21866551
14. Sirnes S, Honne H, Ahmed D, Danielsen SA, Rognum TO, Meling GI, Leithe E, Rivedal E, Lothe RA, Lind GE (2011)
    DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
    Epigenetics, 6 (5), 602-9
    DOI 10.4161/epi.6.5.15237, PubMed 21406965
15. Sjo OH, Berg M, Merok MA, Kolberg M, Svindland A, Lothe RA, Nesbakken A (2011)
    Peritoneal carcinomatosis of colon cancer origin: highest incidence in women and in patients with right-sided tumors
    J Surg Oncol, 104 (7), 792-7
    DOI 10.1002/jso.21959, PubMed 21547915
16. Sveen A, Agesen TH, Nesbakken A, Rognum TO, Lothe RA, Skotheim RI (2011)
    Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
    Genome Med, 3 (5), 32
    DOI 10.1186/gm248, PubMed 21619627
17. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
    CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
    Genes Immun, 12 (8), 653-62
    DOI 10.1038/gene.2011.43, PubMed 21716316

Publications 2010

1. Berg M, Agesen TH, Thiis-Evensen E, INFAC-study group, Merok MA, Teixeira MR, Vatn MH, Nesbakken A, Skotheim RI, Lothe RA (2010)
   Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
   Mol Cancer, 9, 100
   DOI 10.1186/1476-4598-9-100, PubMed 20459617
2. Berg M, Danielsen SA, Ahlquist T, Merok MA, Ågesen TH, Vatn MH, Mala T, Sjo OH, Bakka A, Moberg I, Fetveit T, Mathisen Ø, Husby A, Sandvik O, Nesbakken A, Thiis-Evensen E, Lothe RA (2010)
   DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
   PLoS One, 5 (11), e13978
   DOI 10.1371/journal.pone.0013978, PubMed 21103049
3. Berge G, Costea DE, Berg M, Rasmussen H, Grotterød I, Lothe RA, Mælandsmo GM, Flatmark K (2010)
   Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma
   Amino Acids, 41 (4), 875-84
   DOI 10.1007/s00726-010-0514-6, PubMed 20191297
4. Brekke HR, Ribeiro FR, Kolberg M, Agesen TH, Lind GE, Eknaes M, Hall KS, Bjerkehagen B, van den Berg E, Teixeira MR, Mandahl N, Smeland S, Mertens F, Skotheim RI, Lothe RA (2010)
   Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group
   J Clin Oncol, 28 (9), 1573-82
   DOI 10.1200/JCO.2009.24.8989, PubMed 20159821
5. Burum-Auensen E, Skotheim RI, Schjølberg AR, Røislien J, Lothe RA, Clausen OP (2010)
   Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
   J Carcinog, 9, 1
   DOI 10.4103/1477-3163.60358, PubMed 20411023
6. Costa VL, Henrique R, Danielsen SA, Duarte-Pereira S, Eknaes M, Skotheim RI, Rodrigues A, Magalhães JS, Oliveira J, Lothe RA, Teixeira MR, Jerónimo C, Lind GE (2010)
   Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples
   Clin Cancer Res, 16 (23), 5842-51
   DOI 10.1158/1078-0432.CCR-10-1312, PubMed 20975101
7. Kjenseth A, Fykerud T, Rivedal E, Leithe E (2010)
   Regulation of gap junction intercellular communication by the ubiquitin system
   Cell Signal, 22 (9), 1267-73
   DOI 10.1016/j.cellsig.2010.03.005, PubMed 20206687
8. Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
   UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
   Autophagy, 6 (7), 863-70
   DOI 10.4161/auto.6.7.13033, PubMed 20724836
9. Kristjansson SR, Jordhoy MS, Nesbakken A, Skovlund E, Bakka A, Johannessen HO, Wyller TB (2010)
   Which elements of a comprehensive geriatric assessment (CGA) predict post-operative complications and early mortality after colorectal cancer surgery?
   J. Geriatr. Oncol., 1 (2), 57-65
   DOI 10.1016/j.jgo.2010.06.001
10. Leithe E, Kjenseth A, Bruun J, Sirnes S, Rivedal E (2010)
    Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
    Toxicol Appl Pharmacol, 247 (1), 10-7
    DOI 10.1016/j.taap.2010.05.006, PubMed 20510257
11. Micci F, Haugom L, Ahlquist T, Andersen HK, Abeler VM, Davidson B, Trope CG, Lothe RA, Heim S (2010)
    Genomic aberrations in borderline ovarian tumors
    J Transl Med, 8, 21
    DOI 10.1186/1479-5876-8-21, PubMed 20184781
12. Micci F, Skotheim RI, Haugom L, Weimer J, Eibak AM, Abeler VM, Trope CG, Arnold N, Lothe RA, Heim S (2010)
    Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes
    Genes Chromosomes Cancer, 49 (11), 1046-53
    DOI 10.1002/gcc.20813, PubMed 20725991
13. Nesbakken A (2010)
    [Pilonidal disease--an underprioritized disorder]
    Tidsskr Nor Laegeforen, 130 (9), 920
    DOI 10.4045/tidsskr.10.0376, PubMed 20453940
14. Pinheiro M, Ahlquist T, Danielsen SA, Lind GE, Veiga I, Pinto C, Costa V, Afonso L, Sousa O, Fragoso M, Santos L, Henrique R, Lopes P, Lopes C, Lothe RA, Teixeira MR (2010)
    Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin
    BMC Cancer, 10, 587
    DOI 10.1186/1471-2407-10-587, PubMed 20979647
15. Zwierzina H, Bardelli A, Ciardiello F, Gariboldi M, Håkansson L, Lambrechts D, Lind GE, Loeffler-Ragg J, Schmoll H, Siena S, Tabernero J, Van Cutsem E (2010)
    Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials
    Curr Opin Mol Ther, 12 (6), 703-11
    PubMed 21154162

Publications 2009

1. Bottillo I, Ahlquist T, Brekke H, Danielsen SA, van den Berg E, Mertens F, Lothe RA, Dallapiccola B (2009)
   Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours
   J Pathol, 217 (5), 693-701
   DOI 10.1002/path.2494, PubMed 19142971
2. Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
   Autophagy in tumour suppression and promotion
   Mol Oncol, 3 (4), 366-75
   DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660
3. Brekke HR, Kolberg M, Skotheim RI, Hall KS, Bjerkehagen B, Risberg B, Domanski HA, Mandahl N, Liestøl K, Smeland S, Danielsen HE, Mertens F, Lothe RA (2009)
   Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors
   Neuro Oncol, 11 (5), 514-28
   DOI 10.1215/15228517-2008-127, PubMed 19182148
4. Danielsen SA, Lind GE, Biornslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2009)
   Novel Mutations of the Suppressor Gene PTEN in Colorectal Carcinomas Stratified by Microsatellite Instability- and TP53 Mutation- Status (vol 29, pg E252, 2008)
   Hum. Mutat., 30 (6), 1023
   DOI 10.1002/humu.21048
5. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
   Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
   Pharmacogenet Genomics, 19 (10), 751-9
   DOI 10.1097/FPC.0b013e3283304253, PubMed 19741569
6. Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
   Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
   J Cell Sci, 122 (Pt 21), 3883-93
   DOI 10.1242/jcs.053801, PubMed 19808888
7. Micci F, Haugom L, Ahlquist T, Abeler VM, Trope CG, Lothe RA, Heim S (2009)
   Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution
   J Oncol, 2010, 646340
   DOI 10.1155/2010/646340, PubMed 19759843
8. Micci F, Weimer J, Haugom L, Skotheim RI, Grunewald R, Abeler VM, Silins I, Lothe RA, Trope CG, Arnold N, Heim S (2009)
   Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map
   Genes Chromosomes Cancer, 48 (2), 184-93
   DOI 10.1002/gcc.20628, PubMed 18973136
9. Pretorius ME, Waehre H, Abeler VM, Davidson B, Vlatkovic L, Lothe RA, Giercksky KE, Danielsen HE (2009)
   Large scale genomic instability as an additive prognostic marker in early prostate cancer
   Cell Oncol, 31 (4), 251-9
   DOI 10.3233/CLO-2009-0463, PubMed 19633362
10. Rivedal E, Witz G, Leithe E (2009)
    Gap junction intercellular communication and benzene toxicity
    Chem Biol Interact, 184 (1-2), 229-32
    DOI 10.1016/j.cbi.2009.11.013, PubMed 19932693
11. Sirnes S, Kjenseth A, Leithe E, Rivedal E (2009)
    Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
    Biochem Biophys Res Commun, 382 (1), 41-5
    DOI 10.1016/j.bbrc.2009.02.141, PubMed 19258009
12. Skotheim RI, Thomassen GO, Eken M, Lind GE, Micci F, Ribeiro FR, Cerveira N, Teixeira MR, Heim S, Rognes T, Lothe RA (2009)
    A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
    Mol Cancer, 8, 5
    DOI 10.1186/1476-4598-8-5, PubMed 19152679

Publications 2008

1. Ahlquist T, Bottillo I, Danielsen SA, Meling GI, Rognum TO, Lind GE, Dallapiccola B, Lothe RA (2008)
   RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
   Neoplasia, 10 (7), 680-6, 2 p following 686
   DOI 10.1593/neo.08312, PubMed 18592002
2. Ahlquist T, Lind GE, Costa VL, Meling GI, Vatn M, Hoff GS, Rognum TO, Skotheim RI, Thiis-Evensen E, Lothe RA (2008)
   Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
   Mol Cancer, 7, 94
   DOI 10.1186/1476-4598-7-94, PubMed 19117505
3. Alagaratnam S, Hardy JR, Lothe RA, Skotheim RI, Byrne JA (2008)
   TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours
   Mol Cell Endocrinol, 306 (1-2), 75-80
   DOI 10.1016/j.mce.2008.10.043, PubMed 19041365
4. Danielsen SA, Lind GE, Bjørnslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2008)
   Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
   Hum Mutat, 29 (11), E252-62
   DOI 10.1002/humu.20860, PubMed 18781614
5. Faerden AE, Sjo OH, Andersen SN, Hauglann B, Nazir N, Gravdehaug B, Moberg I, Svinland A, Nesbakken A, Bakka A (2008)
   Sentinel node mapping does not improve staging of lymph node metastasis in colonic cancer
   Dis Colon Rectum, 51 (6), 891-6
   DOI 10.1007/s10350-007-9185-0, PubMed 18259817
6. Hofstad B, Nesbakken A, Eritsland J, Brørs O, Sandset PM (2008)
   [Should platelet inhibitors be discontinued before gastrointestinal endoscopy?]
   Tidsskr Nor Laegeforen, 128 (21), 2440-2
   PubMed 19096466
7. Lind GE, Ahlquist T, Kolberg M, Berg M, Eknaes M, Alonso MA, Kallioniemi A, Meling GI, Skotheim RI, Rognum TO, Thiis-Evensen E, Lothe RA (2008)
   Hypermethylated MAL gene - a silent marker of early colon tumorigenesis
   J Transl Med, 6, 13
   DOI 10.1186/1479-5876-6-13, PubMed 18346269
8. Rivedal E, Leithe E (2008)
   The benzene metabolite trans,trans-muconaldehyde blocks gap junction intercellular communication by cross-linking connexin43
   Toxicol Appl Pharmacol, 232 (3), 463-8
   DOI 10.1016/j.taap.2008.07.022, PubMed 18723040
9. Sirnes S, Leithe E, Rivedal E (2008)
   The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
   Biochem Biophys Res Commun, 373 (4), 597-601
   DOI 10.1016/j.bbrc.2008.06.095, PubMed 18601906

Publications 2007

1. Almstrup K, Leffers H, Lothe RA, Skakkebaek NE, Sonne SB, Nielsen JE, Rajpert-De Meyts E, Skotheim RI (2007)
   Improved gene expression signature of testicular carcinoma in situ
   Int J Androl, 30 (4), 292-302; discussion 303
   DOI 10.1111/j.1365-2605.2007.00758.x, PubMed 17488342
2. Hoei-Hansen CE, Kraggerud SM, Abeler VM, Kaern J, Rajpert-De Meyts E, Lothe RA (2007)
   Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers
   Mol Cancer, 6, 12
   DOI 10.1186/1476-4598-6-12, PubMed 17274819
3. Hofstad B, Andersen SN, Nesbakken A (2007)
   [Colorectal polyps]
   Tidsskr Nor Laegeforen, 127 (20), 2692-5
   PubMed 17952154
4. Kleivi K, Lind GE, Diep CB, Meling GI, Brandal LT, Nesland JM, Myklebost O, Rognum TO, Giercksky KE, Skotheim RI, Lothe RA (2007)
   Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
   Mol Cancer, 6, 2
   DOI 10.1186/1476-4598-6-2, PubMed 17201907
5. Leithe E, Rivedal E (2007)
   Ubiquitination of gap junction proteins
   J Membr Biol, 217 (1-3), 43-51
   DOI 10.1007/s00232-007-9050-z, PubMed 17657522
6. Lind GE, Ahlquist T, Lothe RA (2007)
   DNA hypermethylation of MAL: a promising diagnostic biomarker for colorectal tumors
   Gastroenterology, 132 (4), 1631-2; author reply 1632
   DOI 10.1053/j.gastro.2007.03.003, PubMed 17408629
7. Lind GE, Skotheim RI, Lothe RA (2007)
   The epigenome of testicular germ cell tumors
   APMIS, 115 (10), 1147-60
   DOI 10.1111/j.1600-0463.2007.apm_660.xml.x, PubMed 18042148
8. Oldenburg J, Kraggerud SM, Brydøy M, Cvancarova M, Lothe RA, Fossa SD (2007)
   Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
   J Transl Med, 5, 70
   DOI 10.1186/1479-5876-5-70, PubMed 18162130
9. Oldenburg J, Kraggerud SM, Cvancarova M, Lothe RA, Fossa SD (2007)
   Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors
   J Clin Oncol, 25 (6), 708-14
   DOI 10.1200/JCO.2006.08.9599, PubMed 17228018
10. Røyrvik EC, Ahlquist T, Rognes T, Lothe RA (2007)
    Slip slidin' away: a duodecennial review of targeted genes in mismatch repair deficient colorectal cancer
    Crit Rev Oncog, 13 (3), 229-57
    DOI 10.1615/critrevoncog.v13.i3.20, PubMed 18298386
11. Sjo OH, Lunde OC, Nygaard K, Sandvik L, Nesbakken A (2007)
    Tumour location is a prognostic factor for survival in colonic cancer patients
    Colorectal Dis, 10 (1), 33-40
    DOI 10.1111/j.1463-1318.2007.01302.x, PubMed 17672872
12. Søvik TT, Aasheim ET, Kristinsson J, Schou CF, Nesbakken A, Mala T (2007)
    [Surgical treatment of morbid obesity at a regional center]
    Tidsskr Nor Laegeforen, 127 (1), 47-9
    PubMed 17205090
13. Wu Q, Lind GE, Aasheim HC, Micci F, Silins I, Tropé CG, Nesland JM, Lothe RA, Suo Z (2007)
    The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers
    Epigenetics, 2 (4), 237-43
    DOI 10.4161/epi.2.4.5406, PubMed 18281782
14. Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE (2007)
    DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
    Mol Cancer, 6, 45
    DOI 10.1186/1476-4598-6-45, PubMed 17623056

Publications 2006

1. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC, Lothe RA (2006)
   The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
   Genes Chromosomes Cancer, 45 (1), 31-41
   DOI 10.1002/gcc.20261, PubMed 16145679
2. Iacopetta B, Russo A, Bazan V, Dardanoni G, Gebbia N, Soussi T, Kerr D, Elsaleh H, Soong R, Kandioler D, Janschek E, Kappel S, Lung M, Leung CS, Ko JM, Yuen S, Ho J, Leung SY, Crapez E, Duffour J, Ychou M, Leahy DT, O'Donoghue DP, Agnese V, Cascio S et al. (2006)
   Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study
   Ann Oncol, 17 (5), 842-7
   DOI 10.1093/annonc/mdl035, PubMed 16524972
3. Leithe E, Brech A, Rivedal E (2006)
   Endocytic processing of connexin43 gap junctions: a morphological study
   Biochem J, 393 (Pt 1), 59-67
   DOI 10.1042/BJ20050674, PubMed 16162097
4. Leithe E, Sirnes S, Omori Y, Rivedal E (2006)
   Downregulation of gap junctions in cancer cells
   Crit Rev Oncog, 12 (3-4), 225-56
   DOI 10.1615/critrevoncog.v12.i3-4.30, PubMed 17425504
5. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
   ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
   Cell Oncol, 28 (5-6), 259-72
   DOI 10.1155/2006/949506, PubMed 17167179
6. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
   ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
   Cell. Oncol., 28 (5-6), 259-272
7. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Esteller M, Lothe RA (2006)
   Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)
   J Pathol, 210 (4), 441-9
   DOI 10.1002/path.2064, PubMed 17029216
8. Lothe RA, Skotheim RI, Kallioniemi O, Esteller M (2006)
   To the Readers and Future Authors of Critical Reviews in Oncogenesis
   Critical Reviews in Oncogenesis, 12 (1-2), 1-2
   PublikaID 27
9. Ribeiro FR, Diep CB, Jerónimo C, Henrique R, Lopes C, Eknaes M, Lingjaerde OC, Lothe RA, Teixeira MR (2006)
   Statistical dissection of genetic pathways involved in prostate carcinogenesis
   Genes Chromosomes Cancer, 45 (2), 154-63
   DOI 10.1002/gcc.20279, PubMed 16235241
10. Ribeiro FR, Henrique R, Hektoen M, Berg M, Jerónimo C, Teixeira MR, Lothe RA (2006)
    Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
    Mol Cancer, 5, 33
    DOI 10.1186/1476-4598-5-33, PubMed 16952311
11. Ribeiro FR, Jerónimo C, Henrique R, Fonseca D, Oliveira J, Lothe RA, Teixeira MR (2006)
    8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects
    Clin Cancer Res, 12 (13), 3961-70
    DOI 10.1158/1078-0432.CCR-05-1977, PubMed 16818693
12. Skotheim RI, Autio R, Lind GE, Kraggerud SM, Andrews PW, Monni O, Kallioniemi O, Lothe RA (2006)
    Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes
    Cell Oncol, 28 (5-6), 315-26
    DOI 10.1155/2006/219786, PubMed 17167184
13. Storlazzi CT, Brekke HR, Mandahl N, Brosjö O, Smeland S, Lothe RA, Mertens F (2006)
    Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
    J Pathol, 209 (4), 492-500
    DOI 10.1002/path.1998, PubMed 16721726

Publications 2005

1. Agesen TH, Flørenes VA, Molenaar WM, Lind GE, Berner JM, Plaat BE, Komdeur R, Myklebost O, van den Berg E, Lothe RA (2005)
   Expression patterns of cell cycle components in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors
   J Neuropathol Exp Neurol, 64 (1), 74-81
   DOI 10.1093/jnen/64.1.74, PubMed 15715087
2. Castro P, Eknaes M, Teixeira MR, Danielsen HE, Soares P, Lothe RA, Sobrinho-Simões M (2005)
   Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes
   J Pathol, 206 (3), 305-11
   DOI 10.1002/path.1772, PubMed 15852498
3. Guren MG, Eriksen MT, Wiig JN, Carlsen E, Nesbakken A, Sigurdsson HK, Wibe A, Tveit KM, Norwegian Rectal Cancer Group (2005)
   Quality of life and functional outcome following anterior or abdominoperineal resection for rectal cancer
   Eur J Surg Oncol, 31 (7), 735-42
   DOI 10.1016/j.ejso.2005.05.004, PubMed 16180267
4. Hofer MD, Browne TJ, He L, Skotheim RI, Lothe RA, Rubin MA (2005)
   Identification of two molecular groups of seminomas by using expression and tissue microarrays
   Clin Cancer Res, 11 (16), 5722-9
   DOI 10.1158/1078-0432.CCR-05-0533, PubMed 16115909
5. Kleivi K, Diep CB, Pandis N, Heim S, Teixeira MR, Lothe RA (2005)
   TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas
   J Pathol, 207 (1), 14-9
   DOI 10.1002/path.1812, PubMed 16007576
6. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Henrique R, Saatcioglu F, Esteller M, Teixeira MR, Lothe RA (2005)
   The loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylation
   Mol Cancer, 4 (1), 8
   DOI 10.1186/1476-4598-4-8, PubMed 15691383
7. Skotheim RI, Lind GE, Monni O, Nesland JM, Abeler VM, Fosså SD, Duale N, Brunborg G, Kallioniemi O, Andrews PW, Lothe RA (2005)
   Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development
   Cancer Res, 65 (13), 5588-98
   DOI 10.1158/0008-5472.CAN-05-0153, PubMed 15994931
8. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2005)
   Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
   Methods Mol Biol, 291, 207-16
   DOI 10.1385/1-59259-840-4:207, PubMed 15502225
9. Thorstensen L, Lind GE, Løvig T, Diep CB, Meling GI, Rognum TO, Lothe RA (2005)
   Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability
   Neoplasia, 7 (2), 99-108
   DOI 10.1593/neo.04448, PubMed 15802015

Publications 2004

1. Kildal W, Kaern J, Kraggerud SM, Abeler VM, Sudbø J, Tropè CG, Lothe RA, Danielsen HE (2004)
   Evaluation of genomic changes in a large series of malignant ovarian germ cell tumors--relation to clinicopathologic variables
   Cancer Genet Cytogenet, 155 (1), 25-32
   DOI 10.1016/j.cancergencyto.2004.02.010, PubMed 15527899
2. Kleivi K, Teixeira MR, Eknaes M, Diep CB, Jakobsen KS, Hamelin R, Lothe RA (2004)
   Genome signatures of colon carcinoma cell lines
   Cancer Genet Cytogenet, 155 (2), 119-31
   DOI 10.1016/j.cancergencyto.2004.03.014, PubMed 15571797
3. Richard SM, Bianchi NO, Bianchi MS, Peltomäki P, Lothe RA, Pavicic W (2004)
   Ethnic variation in the prevalence of AZF deletions in testicular cancer
   Mutat Res, 554 (1-2), 45-51
   DOI 10.1016/j.mrfmmm.2004.03.001, PubMed 15450403
4. Teixeira MR, Ribeiro FR, Eknaes M, Waehre H, Stenwig AE, Giercksky KE, Heim S, Lothe RA (2004)
   Genomic analysis of prostate carcinoma specimens obtained via ultrasound-guided needle biopsy may be of use in preoperative decision-making
   Cancer, 101 (8), 1786-93
   DOI 10.1002/cncr.20527, PubMed 15386312
5. Teixeira MR, Ribeiro FR, Torres L, Pandis N, Andersen JA, Lothe RA, Heim S (2004)
   Assessment of clonal relationships in ipsilateral and bilateral multiple breast carcinomas by comparative genomic hybridisation and hierarchical clustering analysis
   Br J Cancer, 91 (4), 775-82
   DOI 10.1038/sj.bjc.6602021, PubMed 15266323

Publications 2003

1. Brandal P, Micci F, Bjerkehagen B, Eknaes M, Larramendy M, Lothe RA, Knuutila S, Heim S (2003)
   Molecular cytogenetic characterization of desmoid tumors
   Cancer Genet Cytogenet, 146 (1), 1-7
   DOI 10.1016/s0165-4608(03)00122-5, PubMed 14499689
2. Diep CB, Parada LA, Teixeira MR, Eknaes M, Nesland JM, Johansson B, Lothe RA (2003)
   Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis
   Genes Chromosomes Cancer, 36 (2), 189-97
   DOI 10.1002/gcc.10162, PubMed 12508247
3. Diep CB, Thorstensen L, Meling GI, Skovlund E, Rognum TO, Lothe RA (2003)
   Genetic tumor markers with prognostic impact in Dukes' stages B and C colorectal cancer patients
   J Clin Oncol, 21 (5), 820-9
   DOI 10.1200/JCO.2003.05.190, PubMed 12610180
4. Henriksen J, Aagesen TH, Maelandsmo GM, Lothe RA, Myklebost O, Forus A (2003)
   Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
   Oncogene, 22 (34), 5358-61
   DOI 10.1038/sj.onc.1206671, PubMed 12917637
5. Kildal W, Kraggerud SM, Abeler VM, Heim S, Tropé CG, Kristensen GB, Risberg B, Lothe RA, Danielsen HE (2003)
   Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
   Hum Pathol, 34 (9), 946-9
   DOI 10.1016/s0046-8177(03)00345-9, PubMed 14562293
6. Kraggerud SM, Lee MP, Skotheim RI, Stenwig AE, Fosså SD, Feinberg AP, Lothe RA (2003)
   Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors
   Cancer Genet Cytogenet, 147 (1), 1-8
   DOI 10.1016/s0165-4608(03)00160-2, PubMed 14580764
7. Løvig T, Thorstensen L, Hofstad B, Andersen SN, Clausen OP, Vatn M, Lothe RA, Rognum TO (2003)
   Genetic and protein markers related to in situ growth and multiplicity in small sporadic colorectal adenomas
   Scand J Gastroenterol, 38 (3), 298-306
   DOI 10.1080/00365520310000618, PubMed 12737446
8. Skotheim RI, Abeler VM, Nesland JM, Fosså SD, Holm R, Wagner U, Flørenes VA, Aass N, Kallioniemi OP, Lothe RA (2003)
   Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarrays
   Neoplasia, 5 (5), 397-404
   DOI 10.1016/s1476-5586(03)80042-8, PubMed 14670177
9. Skotheim RI, Kallioniemi A, Bjerkhagen B, Mertens F, Brekke HR, Monni O, Mousses S, Mandahl N, Soeter G, Nesland JM, Smeland S, Kallioniemi OP, Lothe RA (2003)
   Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome
   J Clin Oncol, 21 (24), 4586-91
   DOI 10.1200/JCO.2003.07.067, PubMed 14673046
10. Skotheim RI, Korkmaz KS, Klokk TI, Abeler VM, Korkmaz CG, Nesland JM, Fosså SD, Lothe RA, Saatcioglu F (2003)
    NKX3.1 expression is lost in testicular germ cell tumors
    Am J Pathol, 163 (6), 2149-54
    DOI 10.1016/S0002-9440(10)63571-7, PubMed 14633588
11. Skotheim RI, Lothe RA (2003)
    The testicular germ cell tumour genome
    APMIS, 111 (1), 136-50; discussion 50-1
    DOI 10.1034/j.1600-0463.2003.11101181.x, PubMed 12752254
12. Thorstensen L, Holm R, Lothe RA, Tropé C, Carvalho B, Sobrinho-Simoes M, Seruca R (2003)
    WNT-inducible signaling pathway protein 3, WISP-3, is mutated in microsatellite unstable gastrointestinal carcinomas but not in endometrial carcinomas
    Gastroenterology, 124 (1), 270-1
    DOI 10.1053/gast.2003.50034, PubMed 12512062