Publications

Publications by Alicia Llorente

48 publications found

Publications 2020

  1. Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
    Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
    J Mater Chem B (in press)
    DOI 10.1039/d0tb00861c, PubMed 32627783
  2. Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
    Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
    Cells, 9 (5)
    DOI 10.3390/cells9051171, PubMed 32397238
  3. Skotland T, Sagini K, Sandvig K, Llorente A (2020)
    An emerging focus on lipids in extracellular vesicles
    Adv Drug Deliv Rev (in press)
    DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
  4. Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
    Analytical techniques for multiplex analysis of protein biomarkers
    Expert Rev Proteomics, 17 (4), 257-273
    DOI 10.1080/14789450.2020.1763174, PubMed 32427033

Publications 2019

  1. Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    J Extracell Vesicles, 8 (1), 1684862
    DOI 10.1080/20013078.2019.1684862, PubMed 31762963

Publications 2018

  1. Clayton A, Buschmann D, Byrd JB, Carter DRF, Cheng L, Compton C, Daaboul G, Devitt A, Falcon-Perez JM, Gardiner C, Gustafson D, Harrison P, Helmbrecht C, Hendrix A, Hill A, Hoffman A, Jones JC, Kalluri R, Kang JY, Kirchner B, Lässer C, Lawson C, Lenassi M, Levin C, Llorente A et al. (2018)
    Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017
    J Extracell Vesicles, 7 (1), 1473707
    DOI 10.1080/20013078.2018.1473707, PubMed 31162490
  2. Popēna I, Ābols A, Saulīte L, Pleiko K, Zandberga E, Jēkabsons K, Endzeliņš E, Llorente A, Linē A, Riekstiņa U (2018)
    Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
    Cell Commun Signal, 16 (1), 17
    DOI 10.1186/s12964-018-0229-y, PubMed 29690889
  3. Ruiz de Garibay G, Herranz C, Llorente A, Boni J, Serra-Musach J, Mateo F, Aguilar H, Gómez-Baldó L, Petit A, Vidal A, Climent F, Hernández-Losa J, Cordero Á, González-Suárez E, Sánchez-Mut JV, Esteller M, Llatjós R, Varela M, López JI, García N, Extremera AI, Gumà A, Ortega R, Plà MJ, Fernández A et al. (2018)
    Correction: Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness
    PLoS One, 13 (11), e0207586
    DOI 10.1371/journal.pone.0207586, PubMed 30419005
  4. Skotland T, Hessvik NP, Sandvig K, Llorente A (2018)
    Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
    J Lipid Res, 60 (1), 9-18
    DOI 10.1194/jlr.R084343, PubMed 30076207
  5. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E et al. (2018)
    Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
    J Extracell Vesicles, 7 (1), 1535750
    DOI 10.1080/20013078.2018.1535750, PubMed 30637094

Publications 2017

  1. Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
    Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
    BMC Cancer, 17 (1), 730
    DOI 10.1186/s12885-017-3737-z, PubMed 29121858
  2. Hessvik NP, Llorente A (2017)
    Current knowledge on exosome biogenesis and release
    Cell Mol Life Sci, 75 (2), 193-208
    DOI 10.1007/s00018-017-2595-9, PubMed 28733901
  3. Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
    A novel community driven software for functional enrichment analysis of extracellular vesicles data
    J Extracell Vesicles, 6 (1), 1321455
    DOI 10.1080/20013078.2017.1321455, PubMed 28717418
  4. Rodríguez M, Bajo-Santos C, Hessvik NP, Lorenz S, Fromm B, Berge V, Sandvig K, Linē A, Llorente A (2017)
    Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes
    Mol Cancer, 16 (1), 156
    DOI 10.1186/s12943-017-0726-4, PubMed 28982366
  5. Sadovska L, Zandberga E, Sagini K, Jēkabsons K, Riekstiņa U, Kalniņa Z, Llorente A, Linē A (2017)
    A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication
    Biochem Biophys Res Commun, 495 (2), 1930-1935
    DOI 10.1016/j.bbrc.2017.12.072, PubMed 29248729
  6. Skotland T, Sandvig K, Llorente A (2017)
    Lipids in exosomes: Current knowledge and the way forward
    Prog Lipid Res, 66, 30-41
    DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
  7. Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
    Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
    J Extracell Vesicles, 6 (1), 1344087
    DOI 10.1080/20013078.2017.1344087, PubMed 28804597

Publications 2016

  1. Endzeliņš E, Melne V, Kalniņa Z, Lietuvietis V, Riekstiņa U, Llorente A, Linē A (2016)
    Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review
    Mol Cancer, 15 (1), 41
    DOI 10.1186/s12943-016-0523-5, PubMed 27189160
  2. Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C et al. (2016)
    Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
    ACS Nano, 10 (4), 3886-99
    DOI 10.1021/acsnano.5b08015, PubMed 26978483
  3. Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
    PIKfyve inhibition increases exosome release and induces secretory autophagy
    Cell Mol Life Sci, 73 (24), 4717-4737
    DOI 10.1007/s00018-016-2309-8, PubMed 27438886
  4. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
    Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
    Data Brief, 7, 1171-1174
    DOI 10.1016/j.dib.2016.03.067, PubMed 27761499
  5. Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
    Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
    Eur J Cancer, 70, 122-132
    DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
  6. Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
    Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
    Eur J Pharm Sci, 98, 80-85
    DOI 10.1016/j.ejps.2016.09.023, PubMed 27664330

Publications 2015

  1. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
    Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
    Biochim Biophys Acta, 1858 (2), 281-8
    DOI 10.1016/j.bbamem.2015.12.003, PubMed 26654782
  2. Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M et al. (2015)
    Biological properties of extracellular vesicles and their physiological functions
    J Extracell Vesicles, 4, 27066
    DOI 10.3402/jev.v4.27066, PubMed 25979354
  3. Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
    Identification of prostate cancer biomarkers in urinary exosomes
    Oncotarget, 6 (30), 30357-76
    DOI 10.18632/oncotarget.4851, PubMed 26196085

Publications 2014

  1. Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
    Regulation of exosome release by glycosphingolipids and flotillins
    FEBS J, 281 (9), 2214-27
    DOI 10.1111/febs.12775, PubMed 24605801
  2. Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
    The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
    J Biol Chem, 290 (7), 4225-37
    DOI 10.1074/jbc.M114.593962, PubMed 25519911

Publications 2013

  1. Hessvik NP, Sandvig K, Llorente A (2013)
    Exosomal miRNAs as Biomarkers for Prostate Cancer
    Front Genet, 4, 36
    DOI 10.3389/fgene.2013.00036, PubMed 23519132
  2. Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
    Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
    Biochim Biophys Acta, 1831 (7), 1302-9
    DOI 10.1016/j.bbalip.2013.04.011, PubMed 24046871

Publications 2012

  1. Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
    Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
    Biochim Biophys Acta, 1819 (11-12), 1154-63
    DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
  2. Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK et al. (2012)
    Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
    PLoS Biol, 10 (12), e1001450
    DOI 10.1371/journal.pbio.1001450, PubMed 23271954
  3. Sandvig K, Llorente A (2012)
    Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
    Mol Cell Proteomics, 11 (7), M111.012914
    DOI 10.1074/mcp.M111.012914, PubMed 22457534

Publications 2007

  1. Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
    Structural requirements for furin-induced cleavage and activation of Shiga toxin
    Biochem Biophys Res Commun, 357 (1), 144-9
    DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
  2. Llorente A, van Deurs B, Sandvig K (2007)
    Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
    Eur J Cell Biol, 86 (7), 405-15
    DOI 10.1016/j.ejcb.2007.05.001, PubMed 17601634
  3. Spilsberg B, Llorente A, Sandvig K (2007)
    Polyunsaturated fatty acids regulate Shiga toxin transport
    Biochem Biophys Res Commun, 364 (2), 283-8
    DOI 10.1016/j.bbrc.2007.09.126, PubMed 17942073

Publications 2004

  1. Llorente A, de Marco MC, Alonso MA (2004)
    Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line
    J Cell Sci, 117 (Pt 22), 5343-51
    DOI 10.1242/jcs.01420, PubMed 15466889

Publications 2003

  1. Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
    Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
    J Biol Chem, 278 (37), 35850-5
    DOI 10.1074/jbc.M303425200, PubMed 12847103

Publications 2002

  1. Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
    Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
    J Biol Chem, 278 (3), 1991-7
    DOI 10.1074/jbc.M209982200, PubMed 12419802
  2. Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
    Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
    J Cell Sci, 115 (Pt 17), 3449-56
    PubMed 12154075

Publications 2001

  1. Iversen TG, Skretting G, Llorente A, Nicoziani P, van Deurs B, Sandvig K (2001)
    Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
    Mol Biol Cell, 12 (7), 2099-107
    DOI 10.1091/mbc.12.7.2099, PubMed 11452006
  2. Llorente A, Prydz K, Sprangers M, Skretting G, Kolset SO, Sandvig K (2001)
    Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
    J Cell Sci, 114 (Pt 2), 335-43
    PubMed 11148135

Publications 2000

  1. Llorente A, van Deurs B, Garred O, Eker P, Sandvig K (2000)
    Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
    J Cell Sci, 113 ( Pt 7), 1213-21
    PubMed 10704372
  2. Nicoziani P, Vilhardt F, Llorente A, Hilout L, Courtoy PJ, Sandvig K, van Deurs B (2000)
    Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
    Mol Biol Cell, 11 (2), 481-95
    DOI 10.1091/mbc.11.2.481, PubMed 10679008
  3. Sandvig K, Llorente A, Rodal SK, Eker P, Garred O, Stahlhut M, van Deurs B (2000)
    Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
    Eur J Cell Biol, 79 (7), 447-57
    DOI 10.1078/0171-9335-00071, PubMed 10961444

Publications 1998

  1. Llorente A, Rapak A, Schmid SL, van Deurs B, Sandvig K (1998)
    Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
    J Cell Biol, 140 (3), 553-63
    DOI 10.1083/jcb.140.3.553, PubMed 9456316
  2. Llorente A, van Deurs B, Sandvig K (1998)
    Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
    FEBS Lett, 431 (2), 200-4
    DOI 10.1016/s0014-5793(98)00754-6, PubMed 9708902

Publications 1996

  1. Llorente A, Garred O, Holm PK, Eker P, Jacobsen J, van Deurs B, Sandvig K (1996)
    Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
    Exp Cell Res, 227 (2), 298-308
    DOI 10.1006/excr.1996.0279, PubMed 8831568

 
Page visits: 4494