Department of Molecular Cell Biology - Cancer Division, Institute for Cancer Research, Oslo University Hospital HF

Fellowship duration: 1 year starting 2nd quarter 2016.

A position as postdoctoral research fellow is available at the Department of Molecular Cell Biology, Cancer Division, Institute for Cancer Research, Oslo University Hospital. The position is funded by  the European Economic Area (EEA)/Norway Grants Research programme between Norway and Latvia coordinated by the Norwegian Research Council.

The Institute for Cancer Research plays a central role within the field of cancer research both in Norway and internationally. The Institute has seven research departments and more than 320 employees. The Institute has internationally strong research groups within cell and tumor biology, genetics, radiation biology, immunology and cancer prevention.

The position is associated with the Department of Molecular Cell Biology (https://www.ous-research.no/mcb/), and in particular with the Exosomes and Prostate Cancer project group (https://www.ous-research.no/llorente/). Current research areas at the Department of Molecular Cell Biology include intracellular transport and communication, exosomes/extracellular vesicles biology, cancer cell migration, nanoparticles, immunobiology and signaling. The department consists of approximately 70 people and offers a stimulating and attractive work environment. It houses state-of-the art infrastructure needed for molecular biology, cell culturing, cell imaging and electron microscopy. Moreover, the department shares access to the common core facilities at Oslo University Hospital. The department is part of the Centre for Cancer Biomedicine, a Norwegian centre of excellence.

When evaluating the application, emphasis will be given to applicant’s academic and personal abilities to carry out the project. Relevant applicants will be called in for an interview. We invite applications from all interested individuals regardless of gender or ethnicity.

Norwegian applications have to be sent electronically via WebCruiter. International applications have to be sent directly to the contact person via e-mail (Alicia Llorente, E-mail: alillo@rr-research.no).

Brief description of the project:

The objective of the project is to characterize the molecular composition of exosomes in order to identify therapeutic targets and non invasive biomarkers for prostate cancer.

Activities: Isolation of extracellular vesicles from cell line supernatants and biological fluids. Analysis of extracellular vesicles using Western blot, ELISA, flow cytometry, -omics analysis, Nanosight and microscopy. Labelling of extracellular vesicles. Analysis, evaluation and presentation of results.

Qualifications:

• PhD in cell and molecular biology, biotechnology, bioinformatics or medicine.
• Research experience in cell and molecular biology methods including mammalian cell culture, Western blot, ELISA, cell transfection, molecular cloning.

• In addition, it will be considered as an advantage to have experience in exosomes/extracellular vesicles, RNA and microRNA,  next-generation deep sequencing (NGS) analysis, RT-PCR, mass spectrometry, bioinformatic analysis of high-throughput data, statistics.
• Good presentation skills and experience in writing scientific papers.
• Capability to design and perform experiments in a creative way.
• Good organizational skills.
• Capability to work both independently and as a team player.
• Fluent English.

Requirements for the application (in English):

• Cover letter including a statement of motivation and research interests.
• CV summarizing education, positions and other relevant activities.
• A complete list of publications.
• 2-3 references (name, relation to candidate, working address, e-mail and telephone number).

• Duration:
  1 year starting during the 2nd quarter 2016
  
  
• Job type:
  Contract
  
  
• Working hours:
  Full-time
  
  
• Application deadline:
  7 February 2016
  
  
• Contact:
  Alicia Llorente, PhD
  Phone: (+47) 22 78 18 25  
  Cell:  (+47) 90 89 27 82
  E-mail: alillo@rr-research.no