Publications

Publications published since 2018 from OUS - Institute for Cancer Research

900 publications found

Publications 2022

  1. Wolf J, Helland Å, Oh IJ, Migliorino MR, Dziadziuszko R, Wrona A, de Castro J, Mazieres J, Griesinger F, Chlistalla M, Cardona A, Ruf T, Trunzer K, Smoljanovic V, Novello S (2022)
    Final efficacy and safety data, and exploratory molecular profiling from the phase III ALUR study of alectinib versus chemotherapy in crizotinib-pretreated ALK-positive non-small-cell lung cancer
    ESMO Open, 7 (1), 100333 (in press)
    DOI 10.1016/j.esmoop.2021.100333, PubMed 35042152
  2. Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M (2022)
    HLA-independent T cell receptors for targeting tumors with low antigen density
    Nat Med (in press)
    DOI 10.1038/s41591-021-01621-1, PubMed 35027758
  3. Skotheim RI, Axcrona U, Axcrona K (2022)
    Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
    Eur Urol (in press)
    DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159
  4. Hjerkind KV, Johansson ALV, Trewin CB, Russnes HG, Ursin G (2022)
    Incidence of breast cancer subtypes in immigrant and non-immigrant women in Norway
    Breast Cancer Res, 24 (1), 4
    DOI 10.1186/s13058-021-01498-5, PubMed 35012613
  5. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  6. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci
    DOI 10.1111/nyas.14745, PubMed 35000205
  7. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
    DOI 10.1093/nar/gkab1101, PubMed 34850127
  8. Ahearn TU, Zhang H, Michailidou K, Milne RL, Bolla MK, Dennis J, Dunning AM, Lush M, Wang Q, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Augustinsson A, Baten A, Becher H, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H et al. (2022)
    Common variants in breast cancer risk loci predispose to distinct tumor subtypes
    Breast Cancer Res, 24 (1), 2
    DOI 10.1186/s13058-021-01484-x, PubMed 34983606
  9. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  10. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    J Acquir Immune Defic Syndr, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817, PubMed 34878437

Publications 2021

  1. Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A (2021)
    Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
    Sci Total Environ, 152732 (in press)
    DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025
  2. Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
    Cell Rep, 37 (13), 110186
    DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
  3. Ji X, Lin L, Fan J, Li Y, Wei Y, Shen S, Su L, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Zhang R, Chen F, Christiani DC (2021)
    Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC
    Mol Oncol
    DOI 10.1002/1878-0261.13167, PubMed 34932879
  4. White JM, Schiffer JT, Bender Ignacio RA, Xu S, Kainov D, Ianevski A, Aittokallio T, Frieman M, Olinger GG, Polyak SJ (2021)
    Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
    mBio, 12 (6), e0334721
    DOI 10.1128/mbio.03347-21, PubMed 34933447
  5. Meriranta L, Alkodsi A, Pasanen A, Lepistö M, Mapar P, Blaker YN, Jørgensen JM, Karjalainen-Lindsberg ML, Fiskvik I, Mikalsen LTG, Autio M, Björkholm M, Jerkeman M, Fluge Ø, Brown P, Jyrkkiö S, Holte H, Pitkänen E, Ellonen P, Leppa S (2021)
    Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma
    Blood (in press)
    DOI 10.1182/blood.2021012852, PubMed 34932792
  6. Sharma K, Asp NT, Harrison SP, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  7. Reint G, Li Z, Labun K, Keskitalo S, Soppa I, Mamia K, Tolo E, Szymanska M, Meza-Zepeda LA, Lorenz S, Cieslar-Pobuda A, Hu X, Bordin DL, Staerk J, Valen E, Schmierer B, Varjosalo M, Taipale J, Haapaniemi E (2021)
    Rapid genome editing by CRISPR-Cas9-POLD3 fusion
    Elife, 10
    DOI 10.7554/eLife.75415, PubMed 34898428
  8. Jørgensen SF, Buechner J, Myhre AE, Galteland E, Spetalen S, Kulseth MA, Sorte HS, Holla ØL, Lundman E, Alme C, Heier I, Flægstad T, Fløisand Y, Benneche A, Fevang B, Aukrust P, Stray-Pedersen A, Gedde-Dahl T, Nordøy I (2021)
    A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
    J Clin Immunol
    DOI 10.1007/s10875-021-01189-y, PubMed 34893945
  9. Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
    E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
    Mol Oncol
    DOI 10.1002/1878-0261.13159, PubMed 34890102
  10. Larsen SG, Goscinski MA, Dueland S, Steigen SE, Hofsli E, Torgunrud A, Lund-Iversen M, Dagenborg VJ, Flatmark K, Sorbye H (2021)
    Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
    Br J Cancer
    DOI 10.1038/s41416-021-01620-6, PubMed 34887523
  11. Nunes-Xavier CE, Zaldumbide L, Mosteiro L, López-Almaraz R, García de Andoin N, Aguirre P, Emaldi M, Torices L, López JI, Pulido R (2021)
    Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets
    Front Cell Dev Biol, 9, 811297
    DOI 10.3389/fcell.2021.811297, PubMed 34957126
  12. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
  13. Gansmo LB, Sofiyeva N, Bjørnslett M, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
    Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
    Sci Rep, 11 (1), 23463
    DOI 10.1038/s41598-021-02820-z, PubMed 34873230
  14. Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, Knetter C, Odabasi MC, Bollineni RC, Yang X, Foldvari Z, Böschen ML, Taraldsrud E, Strønen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjønnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT et al. (2021)
    T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
    Nat Biotechnol
    DOI 10.1038/s41587-021-01089-x, PubMed 34873326
  15. Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
    Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
    Hepatology, 75 (1), 59-73
    DOI 10.1002/hep.32125, PubMed 34435693
  16. Lien TG, Ohnstad HO, Lingjærde OC, Vallon-Christersson J, Aaserud M, Sveli MAT, Borg Å, Osbreac OBO, Garred Ø, Borgen E, Naume B, Russnes H, Sørlie T (2021)
    Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
    Cancers (Basel), 13 (23)
    DOI 10.3390/cancers13236118, PubMed 34885228
  17. Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol Oncol
    DOI 10.1002/1878-0261.13153, PubMed 34861096
  18. Klopotowska M, Bajor M, Graczyk-Jarzynka A, Kraft A, Pilch Z, Zhylko A, Firczuk M, Baranowska I, Lazniewski M, Plewczynski D, Goral A, Soroczynska K, Domagala J, Marhelava K, Slusarczyk A, Retecki K, Ramji K, Krawczyk M, Temples MN, Sharma B, Lachota M, Netskar H, Malmberg KJ, Zagozdzon R, Winiarska M (2021)
    PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress
    Cancer Immunol Res (in press)
    DOI 10.1158/2326-6066.CIR-20-1023, PubMed 34853030
  19. Tamhane T, Njenga RW, Burden RE, Bueth H, Maelandsmo GM, Haugen MH, Scott CJ, Brix K (2021)
    Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
    Appl. Sci.-Basel, 11 (24), 11936
    DOI 10.3390/app112411936
  20. Hølmebakk T, Boye K (2021)
    Correction to: ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (Suppl 3), 873
    DOI 10.1245/s10434-021-09939-3, PubMed 33829360
  21. Hamfjord J, Myklebust TÅ, Larsen IK, Kure EH, Glimelius B, Guren TK, Tveit KM, Guren MG (2021)
    Survival Trends of Right- and Left-Sided Colon Cancer across Four Decades: A Norwegian Population-Based Study
    Cancer Epidemiol Biomarkers Prev (in press)
    DOI 10.1158/1055-9965.EPI-21-0555, PubMed 34853022
  22. Grigalavicius M, Mastrangelopoulou M, Berg K, Arous D, Ménard M, Raabe-Henriksen T, Brondz E, Siem S, Görgen A, Edin NFJ, Malinen E, Theodossiou TA (2021)
    Publisher Correction: Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
    Nat Commun, 12 (1), 7073
    DOI 10.1038/s41467-021-27175-x, PubMed 34848706
  23. Li H, Engel C, de la Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2021)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (1), 119-129
    DOI 10.1016/j.gim.2021.08.016, PubMed 34906479
  24. Andresen M, Sletten M, Sandset PM, Iversen N, Stavik B, Tinholt M (2021)
    Coagulation factor 5 (F5) is an estrogen-responsive gene in breast cancer cells
    Thromb Haemost (in press)
    DOI 10.1055/a-1707-2130, PubMed 34826880
  25. Isaksen KT, Mastroianni MA, Rinde M, Rusten LS, Barzenje DA, Ramslien LF, Slaaen M, Jerm MB, Smeland EB, Rostoft S, Liestøl K, Brodtkorb M, Holte H (2021)
    A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
    Blood Adv, 5 (22), 4771-4782
    DOI 10.1182/bloodadvances.2021004777, PubMed 34543384
  26. Li RG, Lindland K, Bønsdorff TB, Westrøm S, Larsen RH (2021)
    A Novel Single-Step-Labeled 212Pb-CaCO3 Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice
    Materials (Basel), 14 (23)
    DOI 10.3390/ma14237130, PubMed 34885283
  27. Ramirez-Garrastacho M, Bajo-Santos C, Line A, Martens-Uzunova ES, de la Fuente JM, Moros M, Soekmadji C, Tasken KA, Llorente A (2021)
    Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
    Br J Cancer
    DOI 10.1038/s41416-021-01610-8, PubMed 34811504
  28. Ramirez-Garrastacho M, Berge V, Linē A, Llorente A (2021)
    Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients
    Br J Cancer
    DOI 10.1038/s41416-021-01598-1, PubMed 34811506
  29. Jenum S, Tonby K, Rueegg CS, Rühwald M, Kristiansen MP, Bang P, Olsen IC, Sellæg K, Røstad K, Mustafa T, Taskén K, Kvale D, Mortensen R, Dyrhol-Riise AM (2021)
    A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
    Nat Commun, 12 (1), 6774
    DOI 10.1038/s41467-021-27029-6, PubMed 34811370
  30. Valko A, Perez-Pandolfo S, Sorianello E, Brech A, Wappner P, Melani M (2021)
    Adaptation to hypoxia in Drosophila melanogaster requires autophagy
    Autophagy
    DOI 10.1080/15548627.2021.1991191, PubMed 34793268
  31. Frafjord A, Buer L, Hammarström C, Aamodt H, Woldbæk PR, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2021)
    The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
    Front Immunol, 12, 764596
    DOI 10.3389/fimmu.2021.764596, PubMed 34868011
  32. Malani D, Kumar A, Brück O, Kontro M, Yadav B, Hellesøy M, Kuusanmäki H, Dufva O, Kankainen M, Eldfors S, Potdar S, Saarela J, Turunen L, Parsons A, Västrik I, Kivinen K, Saarela J, Räty R, Lehto M, Wolf M, Gjertsen BT, Mustjoki S, Aittokallio T, Wennerberg K, Heckman CA et al. (2021)
    Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
    Cancer Discov (in press)
    DOI 10.1158/2159-8290.CD-21-0410, PubMed 34789538
  33. Kang W, Fromm B, Houben AJ, Høye E, Bezdan D, Arnan C, Thrane K, Asp M, Johnson R, Biryukova I, Friedländer MR (2021)
    MapToCleave: High-throughput profiling of microRNA biogenesis in living cells
    Cell Rep, 37 (7), 110015
    DOI 10.1016/j.celrep.2021.110015, PubMed 34788611
  34. Wang N, Bai D, Kristiansen E, Deng R, Zhang S (2021)
    AKIP1 promotes tumor progression by cancer-related pathways and predicts prognosis in tongue squamous cell carcinoma
    Am J Transl Res, 13 (11), 12338-12351
    PubMed 34956456
  35. Lai X, Taskén HA, Mo T, Funke SW, Frigessi A, Rognes ME, Köhn-Luque A (2021)
    A scalable solver for a stochastic, hybrid cellular automaton model of personalized breast cancer therapy
    Int J Numer Method Biomed Eng, 38 (1), e3542
    DOI 10.1002/cnm.3542, PubMed 34716985
  36. Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
    The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
    Nat Commun, 12 (1), 6577
    DOI 10.1038/s41467-021-26775-x, PubMed 34772942
  37. Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
    Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
    Biochem Pharmacol, 194, 114837
    DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
  38. Larrinaga G, Calvete-Candenas J, Solano-Iturri JD, Martín AM, Pueyo A, Nunes-Xavier CE, Pulido R, Dorado JF, López JI, Angulo JC (2021)
    (Pro)renin Receptor Is a Novel Independent Prognostic Marker in Invasive Urothelial Carcinoma of the Bladder
    Cancers (Basel), 13 (22)
    DOI 10.3390/cancers13225642, PubMed 34830803
  39. Erdélyi K, Ditrói T, Johansson HJ, Czikora Á, Balog N, Silwal-Pandit L, Ida T, Olasz J, Hajdú D, Mátrai Z, Csuka O, Uchida K, Tóvári J, Engebraten O, Akaike T, Børresen Dale AL, Kásler M, Lehtiö J, Nagy P (2021)
    Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation
    Proc Natl Acad Sci U S A, 118 (45)
    DOI 10.1073/pnas.2100050118, PubMed 34737229
  40. Bengtsen M, Winje IM, Eftestøl E, Landskron J, Sun C, Nygård K, Domanska D, Millay DP, Meza-Zepeda LA, Gundersen K (2021)
    Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle
    PLoS Genet, 17 (11), e1009907
    DOI 10.1371/journal.pgen.1009907, PubMed 34752468
  41. Wong JJW, Selbo PK (2021)
    Light-controlled elimination of PD-L1+ cells
    J Photochem Photobiol B, 225, 112355
    DOI 10.1016/j.jphotobiol.2021.112355, PubMed 34768077
  42. Rønneberg L, Cremaschi A, Hanes R, Enserink JM, Zucknick M (2021)
    bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
    Brief Bioinform, 22 (6)
    DOI 10.1093/bib/bbab251, PubMed 34308471
  43. Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
    Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
    Autophagy
    DOI 10.1080/15548627.2021.1988359, PubMed 34740308
  44. Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
    RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
    Nat Commun, 12 (1), 6427
    DOI 10.1038/s41467-021-26018-z, PubMed 34741021
  45. Roeker LE, Eyre TA, Thompson MC, Lamanna N, Coltoff AR, Davids MS, Baker PO, Leslie L, Rogers KA, Allan JN, Cordoba R, Lopez-Garcia A, Antic D, Pagel JM, Martinez-Calle N, García-Marco JA, Hernández-Rivas JÁ, Miras F, Coombs CC, Österborg A, Hansson L, Seddon AN, López Jiménez J, Wilson MR, El-Sharkawi D et al. (2021)
    COVID-19 in patients with CLL: improved survival outcomes and update on management strategies
    Blood, 138 (18), 1768-1773
    DOI 10.1182/blood.2021011841, PubMed 34297826
  46. Sioud M, Juzenas P, Zhang Q, Kleinauskas A, Peng Q (2021)
    Correction: Sioud et al. Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Monolayer and Multicellular Tumor Spheroid Models. Cancers 2021, 13, 3356
    Cancers (Basel), 13 (21)
    DOI 10.3390/cancers13215513, PubMed 34771754
  47. White JM, Schiffer JT, Ignacio RAB, Xu S, Kainov D, Ianevski A, Aittokallio T, Frieman M, Olinger GG, Polyak SJ (2021)
    Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
    mBio, 12 (6), e03347-21
  48. Lehtiö J, Arslan T, Siavelis I, Pan Y, Socciarelli F, Berkovska O, Umer HM, Mermelekas G, Pirmoradian M, Jönsson M, Brunnström H, Brustugun OT, Purohit KP, Cunningham R, Asl HF, Isaksson S, Arbajian E, Aine M, Karlsson A, Kotevska M, Hansen CG, Haakensen VD, Helland Å, Tamborero D, Johansson HJ et al. (2021)
    Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms
    Nat Cancer, 2 (11), 1224-1242
    DOI 10.1038/s43018-021-00259-9, PubMed 34870237
  49. Pavlovic M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML et al. (2021)
    The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
    Nat. Mach. Intell., 3 (11), 936-+
    DOI 10.1038/s42256-021-00413-z
  50. Levy-Jurgenson A, Tekpli X, Yakhini Z (2021)
    Erratum to: Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging
    Bioinformatics (in press)
    DOI 10.1093/bioinformatics/btab692, PubMed 34718412
  51. Sohlberg E, Pfefferle A, Ask EH, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ (2021)
    Perturbed NK Cell Homeostasis Associated with Disease Severity in Chronic Neutropenia
    Blood (in press)
    DOI 10.1182/blood.2021013233, PubMed 34699594
  52. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  53. Aasebø K, Bruun J, Bergsland CH, Nunes L, Eide GE, Pfeiffer P, Dahl O, Glimelius B, Lothe RA, Sorbye H (2021)
    Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
    Br J Cancer, 126 (1), 48-56
    DOI 10.1038/s41416-021-01586-5, PubMed 34671130
  54. Ballester PJ, Stevens R, Haibe-Kains B, Huang RS, Aittokallio T (2021)
    Artificial intelligence for drug response prediction in disease models
    Brief Bioinform (in press)
    DOI 10.1093/bib/bbab450, PubMed 34655289
  55. Lingjærde C, Lien TG, Borgan Ø, Bergholtz H, Glad IK (2021)
    Tailored graphical lasso for data integration in gene network reconstruction
    BMC Bioinformatics, 22 (1), 498
    DOI 10.1186/s12859-021-04413-z, PubMed 34654363
  56. Bjaanæs MM, Nilsen G, Halvorsen AR, Russnes HG, Solberg S, Jørgensen L, Brustugun OT, Lingjærde OC, Helland Å (2021)
    Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
    BMC Cancer, 21 (1), 1089
    DOI 10.1186/s12885-021-08811-7, PubMed 34625038
  57. Mazzarella L, Enblad G, Olweus J, Malmberg KJ, Jerkeman M (2021)
    Advances in immune therapies in hematological malignancies
    J Intern Med
    DOI 10.1111/joim.13395, PubMed 34624160
  58. Lorvik KB, Meyer-Myklestad MH, Kushekar K, Handeland C, Medhus AW, Lund-Iversen M, Stiksrud B, Kvale D, Dyrhol-Riise AM, Taskén K, Reikvam DH (2021)
    Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
    Front Immunol, 12, 744155
    DOI 10.3389/fimmu.2021.744155, PubMed 34691047
  59. Martens-Uzunova ES, Blijdorp CJ, Burger D, Erdbrügger U, Llorente A (2021)
    Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead
    Eur Urol, 81 (1), 127-128
    DOI 10.1016/j.eururo.2021.09.025, PubMed 34625312
  60. Svendsen HA, Meling TR, Nygaard V, Waagene S, Russnes H, Juell S, Rogne SG, Pahnke J, Helseth E, Fodstad Ø, Maelandsmo GM (2021)
    Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
    Cancer Med, 10 (23), 8604-8613
    DOI 10.1002/cam4.4334, PubMed 34612023
  61. Lone AM, Giansanti P, Jørgensen MJ, Gjerga E, Dugourd A, Scholten A, Saez-Rodriguez J, Heck AJR, Taskén K (2021)
    Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells
    Sci Signal, 14 (703), eabc8579
    DOI 10.1126/scisignal.abc8579, PubMed 34609894
  62. Chellappa S, Kushekhar K, Hagness M, Horneland R, Taskén K, Aandahl EM (2021)
    The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients
    J Immunol, 207 (10), 2501-2511
    DOI 10.4049/jimmunol.2001103, PubMed 34607938
  63. Aranguren-Abadía L, Yadetie F, Donald CE, Sørhus E, Myklatun LE, Zhang X, Lie KK, Perrichon P, Nakken CL, Durif C, Shema S, Browman HI, Skiftesvik AB, Goksøyr A, Meier S, Karlsen OA (2021)
    Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
    Sci Total Environ, 807 (Pt 1), 150697
    DOI 10.1016/j.scitotenv.2021.150697, PubMed 34610396
  64. Flatmark K, Torgunrud A, Fleten KG, Davidson B, Juul HV, Mensali N, Lund-Andersen C, Inderberg EM (2021)
    Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
    J Immunother Cancer, 9 (10)
    DOI 10.1136/jitc-2021-003109, PubMed 34711663
  65. Fromm B, Tarbier M, Smith O, Mármol-Sánchez E, Dalén L, Gilbert MTP, Friedländer MR (2021)
    Corrigendum: Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene
    RNA, 27 (10), 1291
    DOI 10.1261/rna.078885.121, PubMed 34531318
  66. Holmebakk T, Boye K (2021)
    ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Patients with Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann. Surg. Oncol., 28 (11), 6846-6847
    DOI 10.1245/s10434-021-09608-5
  67. Sanjiv K, Calderón-Montaño JM, Pham TM, Erkers T, Tsuber V, Almlöf I, Höglund A, Heshmati Y, Seashore-Ludlow B, Nagesh Danda A, Gad H, Wiita E, Göktürk C, Rasti A, Friedrich S, Centio A, Estruch M, Våtsveen TK, Struyf N, Visnes T, Scobie M, Koolmeister T, Henriksson M, Wallner O, Sandvall T et al. (2021)
    MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
    Cancer Res, 81 (22), 5733-5744
    DOI 10.1158/0008-5472.CAN-21-0061, PubMed 34593524
  68. Steen CB, Luca BA, Esfahani MS, Azizi A, Sworder BJ, Nabet BY, Kurtz DM, Liu CL, Khameneh F, Advani RH, Natkunam Y, Myklebust JH, Diehn M, Gentles AJ, Newman AM, Alizadeh AA (2021)
    The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
    Cancer Cell, 39 (10), 1422-1437.e10
    DOI 10.1016/j.ccell.2021.08.011, PubMed 34597589
  69. Bahrami N, Jabeen S, Tahiri A, Sauer T, Ødegård HP, Geisler SB, Gravdehaug B, Reitsma LC, Selsås K, Kristensen V, Geisler J (2021)
    Lack of cross-resistance between non-steroidal and steroidal aromatase inhibitors in breast cancer patients: the potential role of the adipokine leptin
    Breast Cancer Res Treat, 190 (3), 435-449
    DOI 10.1007/s10549-021-06399-x, PubMed 34554372
  70. Gaustad JV, Rofstad EK (2021)
    Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods
    Front Oncol, 11, 722773
    DOI 10.3389/fonc.2021.722773, PubMed 34621674
  71. Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
    Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
    Biomacromolecules, 22 (10), 4169-4180
    DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
  72. Yaqub S, Bjørnbeth BA, Angelsen JH, Fristrup CW, Grønbech JE, Hemmingsson O, Isaksson B, Juel IS, Larsen PN, Lindell G, Mortensen FV, Mortensen KE, Rizell M, Sandström P, Sandvik OM, Sparrelid E, Taflin H, Taskén K, ASAC study group (2021)
    Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
    Trials, 22 (1), 642
    DOI 10.1186/s13063-021-05587-w, PubMed 34544470
  73. Karvelsson ST, Wang Q, Hilmarsdottir B, Sigurdsson A, Moestue SA, Mælandsmo GM, Halldorsson S, Gudmundsson S, Rolfsson O (2021)
    Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
    NPJ Syst Biol Appl, 7 (1), 36
    DOI 10.1038/s41540-021-00195-5, PubMed 34535676
  74. Woan KV, Kim H, Bjordahl R, Davis ZB, Gaidarova S, Goulding J, Hancock B, Mahmood S, Abujarour R, Wang H, Tuininga K, Zhang B, Wu CY, Kodal B, Khaw M, Bendzick L, Rogers P, Ge MQ, Bonello G, Meza M, Felices M, Huffman J, Dailey T, Lee TT, Walcheck B et al. (2021)
    Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
    Cell Stem Cell, 28 (12), 2062-2075.e5
    DOI 10.1016/j.stem.2021.08.013, PubMed 34525347
  75. Snapkov I, Chernigovskaya M, Sinitcyn P, Lê Quý K, Nyman TA, Greiff V (2021)
    Progress and challenges in mass spectrometry-based analysis of antibody repertoires
    Trends Biotechnol (in press)
    DOI 10.1016/j.tibtech.2021.08.006, PubMed 34535228
  76. Fores-Martos J, Cervera-Vidal R, Sierra-Roca J, Lozano-Asencio C, Fedele V, Cornelissen S, Edvarsen H, Tadeo-Cervera I, Eroles P, Lluch A, Tabares-Seisdedos R, Falcó A, Van't Veer LJ, Schmidt M, Quigley DA, Børresen-Dale AL, Kristensen VN, Balmain A, Climent J (2021)
    Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression
    NPJ Breast Cancer, 7 (1), 118
    DOI 10.1038/s41523-021-00329-2, PubMed 34508103
  77. Jerjes W, Hamdoon Z, Berg K, Høgset A, Hopper C (2021)
    Squamous cell carcinoma of the ear treated by photochemical internalization
    Photodiagnosis Photodyn Ther, 36, 102528
    DOI 10.1016/j.pdpdt.2021.102528, PubMed 34509683
  78. Siokis A, Robert PA, Demetriou P, Kvalvaag A, Valvo S, Mayya V, Dustin ML, Meyer-Hermann M (2021)
    Characterization of mechanisms positioning costimulatory complexes in immune synapses
    iScience, 24 (10), 103100
    DOI 10.1016/j.isci.2021.103100, PubMed 34622155
  79. Aamdal E, Jacobsen KD, Straume O, Kersten C, Herlofsen O, Karlsen J, Hussain I, Amundsen A, Dalhaug A, Nyakas M, Schuster C, Hagene KT, Holmsen K, Russnes HG, Skovlund E, Kaasa S, Aamdal S, Kyte JA, Guren TK (2021)
    Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up
    Int J Cancer, 150 (1), 100-111
    DOI 10.1002/ijc.33768, PubMed 34449877
  80. Kryeziu K, Moosavi SH, Bergsland CH, Guren MG, Eide PW, Totland MZ, Lassen K, Abildgaard A, Nesbakken A, Sveen A, Lothe RA (2021)
    Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
    J Transl Med, 19 (1), 384
    DOI 10.1186/s12967-021-03062-3, PubMed 34496878
  81. Farooqi SJ, Helland A, Haakensen VD, Bjaanaes MM (2021)
    Immunotherapy in malignant pleural mesothelioma
    Tidsskr. Nor. Laegeforen., 141 (12), 1167-1169
  82. Eide IJZ, Grut H, Helland Å, Ekman S, Sørensen JB, Hansen KH, Grønberg BH, Cicenas S, Koivunen JP, Mellemgaard A, Brustugun OT (2021)
    Intracranial effect of osimertinib in relapsed EGFR-mutated T790M-positive and -negative non-small cell lung cancer patients: results from a phase II study
    Acta Oncol, 60 (12), 1565-1571
    DOI 10.1080/0284186X.2021.1973092, PubMed 34486915
  83. Farooqi SJ, Bjaanæs MM, Helland Å, Haakensen VD (2021)
    Immunotherapy for malignant pleural mesothelioma
    Tidsskr Nor Laegeforen, 141
    DOI 10.4045/tidsskr.21.0503, PubMed 34505475
  84. Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T et al. (2021)
    Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
    Nat Commun, 12 (1), 5307
    DOI 10.1038/s41467-021-25624-1, PubMed 34489465
  85. Bergholtz H, Carter JM, Cesano A, Cheang MCU, Church SE, Divakar P, Fuhrman CA, Goel S, Gong J, Guerriero JL, Hoang ML, Hwang ES, Kuasne H, Lee J, Liang Y, Mittendorf EA, Perez J, Prat A, Pusztai L, Reeves JW, Riazalhosseini Y, Richer JK, Sahin Ö, Sato H, Schlam I et al. (2021)
    Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler
    Cancers (Basel), 13 (17)
    DOI 10.3390/cancers13174456, PubMed 34503266
  86. Ragnum HB, De Bortoli AM, Elsais A, Nilsen KB, Hammarström C, Nyakas M (2021)
    A man in his sixties with dyspnoea following immunotherapy
    Tidsskr Nor Laegeforen, 141 (2021-12)
    DOI 10.4045/tidsskr.21.0139, PubMed 34505469
  87. Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Røsok BI, Brudvik KW, Bjørnbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
    De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
    Genome Med, 13 (1), 143
    DOI 10.1186/s13073-021-00956-1, PubMed 34470666
  88. Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
    The expressed mutational landscape of microsatellite stable colorectal cancers
    Genome Med, 13 (1), 142
    DOI 10.1186/s13073-021-00955-2, PubMed 34470667
  89. Öjlert ÅK, Nebdal D, Snapkov I, Olsen V, Kidman J, Greiff V, Chee J, Helland Å (2021)
    Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor
    Mol Oncol, 15 (11), 2958-2968
    DOI 10.1002/1878-0261.13082, PubMed 34402187
  90. Mensali N, Dillard P, Fayzullin A, Köksal H, Gaudernack G, Kvalheim G, Inderberg EM, Wälchli S (2021)
    "Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
    FASEB J, 35 (9), e21750
    DOI 10.1096/fj.202100025R, PubMed 34424568
  91. Møller P, Sampson JR, Dominguez-Valentin M, Seppälä TT (2021)
    Towards evidence-based personalised precision medicine for Lynch syndrome
    Lancet Oncol, 22 (9), e383
    DOI 10.1016/S1470-2045(21)00400-9, PubMed 34478667
  92. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T et al. (2021)
    Autophagy in major human diseases
    EMBO J, 40 (19), e108863
    DOI 10.15252/embj.2021108863, PubMed 34459017
  93. Wiedlocha A, Haugsten EM, Zakrzewska M (2021)
    Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
    Cells, 10 (9)
    DOI 10.3390/cells10092231, PubMed 34571880
  94. Maclachlan KH, Rustad EH, Derkach A, Zheng-Lin B, Yellapantula V, Diamond B, Hultcrantz M, Ziccheddu B, Boyle EM, Blaney P, Bolli N, Zhang Y, Dogan A, Lesokhin AM, Morgan GJ, Landgren O, Maura F (2021)
    Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma
    Nat Commun, 12 (1), 5172
    DOI 10.1038/s41467-021-25469-8, PubMed 34453055
  95. Wahl SGF, Dai HY, Emdal EF, Berg T, Halvorsen TO, Ottestad AL, Lund-Iversen M, Brustugun OT, Førde D, Paulsen EE, Donnem T, Andersen S, Grønberg BH, Richardsen E (2021)
    The Prognostic Effect of KRAS Mutations in Non-Small Cell Lung Carcinoma Revisited: A Norwegian Multicentre Study
    Cancers (Basel), 13 (17)
    DOI 10.3390/cancers13174294, PubMed 34503114
  96. Kim SJ, Lubinski J, Huzarski T, Møller P, Armel S, Karlan BY, Senter L, Eisen A, Foulkes WD, Singer CF, Tung N, Bordeleau L, Neuhausen SL, Olopade OI, Eng C, Weitzel JN, Fruscio R, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2021)
    Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
    Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
    DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412
  97. Moghaddam S, Jalali A, O'Neill A, Murphy L, Gorman L, Reilly AM, Heffernan Á, Lynch T, Power R, O'Malley KJ, Taskèn KA, Berge V, Solhaug VA, Klocker H, Murphy TB, Watson RW (2021)
    Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy
    Cancers (Basel), 13 (16)
    DOI 10.3390/cancers13164162, PubMed 34439316
  98. Dillard C, Reis JGT, Rusten TE (2021)
    RasV12; scrib-/- Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
    Int J Mol Sci, 22 (16)
    DOI 10.3390/ijms22168873, PubMed 34445578
  99. Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn TU, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Augustinsson A, Beane Freeman LE, Becher H, Beckmann MW, Behrens S, Bojesen SE, Bolla MK, Brenner H, Brüning T, Buys SS, Caan B, Campa D, Canzian F, Castelao JE, Chang-Claude J et al. (2021)
    Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
    Breast Cancer Res, 23 (1), 86
    DOI 10.1186/s13058-021-01450-7, PubMed 34407845
  100. Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
    The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
    BMC Cancer, 21 (1), 930
    DOI 10.1186/s12885-021-08640-8, PubMed 34407780
  101. Tulipan AJ, Salberg UB, Hole KH, Vlatkovic L, Aarnes EK, Revheim ME, Lyng H, Seierstad T (2021)
    Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer
    Am J Nucl Med Mol Imaging, 11 (4), 250-259
    PubMed 34513278
  102. de Freitas Germano J, Sharma A, Stastna M, Huang C, Aniag M, Aceves A, Van Eyk JE, Mentzer RM, Piplani H, Andres AM, Gottlieb RA (2021)
    Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy
    Int J Mol Sci, 22 (16)
    DOI 10.3390/ijms22168711, PubMed 34445425
  103. Levy-Jurgenson A, Tekpli X, Yakhini Z (2021)
    Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging
    Bioinformatics, 37 (21), 3796-3804
    DOI 10.1093/bioinformatics/btab569, PubMed 34358288
  104. Nakken S, Saveliev V, Hofmann O, Møller P, Myklebost O, Hovig E (2021)
    Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
    Int J Cancer, 149 (11), 1955-1960
    DOI 10.1002/ijc.33749, PubMed 34310709
  105. Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF (2021)
    Autophagy in healthy aging and disease
    Nat Aging, 1 (8), 634-650
    DOI 10.1038/s43587-021-00098-4, PubMed 34901876
  106. Anda S, Boye E, Schink KO, Grallert B (2021)
    Cosegregation of asymmetric features during cell division
    Open Biol, 11 (8), 210116
    DOI 10.1098/rsob.210116, PubMed 34343465
  107. van der Zanden TM, Mooij MG, Vet NJ, Neubert A, Rascher W, Lagler FB, Male C, Grytli H, Halvorsen T, de Hoog M, de Wildt SN (2021)
    Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
    Clin Pharmacol Ther, 110 (4), 952-965
    DOI 10.1002/cpt.2336, PubMed 34145575
  108. Rødland GE, Hauge S, Hasvold G, Bay LTE, Raabe TTH, Joel M, Syljuåsen RG (2021)
    Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells
    Cancers (Basel), 13 (15)
    DOI 10.3390/cancers13153790, PubMed 34359691
  109. Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
    Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
    EMBO J, 40 (18), e107336
    DOI 10.15252/embj.2020107336, PubMed 34309071
  110. Pluta J, Pyle LC, Nead KT, Wilf R, Li M, Mitra N, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Benitez J, Brown CD, Chanock S, Chen C, Cortessis VK, Ferlin A, Foresta C, Gamulin M, Gietema JA, Grasso C, Greene MH, Grotmol T, Hamilton RJ, Haugen TB, Hauser R et al. (2021)
    Identification of 22 susceptibility loci associated with testicular germ cell tumors
    Nat Commun, 12 (1), 4487
    DOI 10.1038/s41467-021-24334-y, PubMed 34301922
  111. White BS, Khan SA, Mason MJ, Ammad-Ud-Din M, Potdar S, Malani D, Kuusanmäki H, Druker BJ, Heckman C, Kallioniemi O, Kurtz SE, Porkka K, Tognon CE, Tyner JW, Aittokallio T, Wennerberg K, Guinney J (2021)
    Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia
    NPJ Precis Oncol, 5 (1), 71
    DOI 10.1038/s41698-021-00209-9, PubMed 34302041
  112. Christopoulos PF, Grigalavicius M, Corthay A, Berg K, Theodossiou TA (2021)
    Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements
    Antioxidants (Basel), 10 (7)
    DOI 10.3390/antiox10071149, PubMed 34356382
  113. Tan KW, Nähse V, Campsteijn C, Brech A, Schink KO, Stenmark H (2021)
    JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
    J Cell Sci, 134 (14)
    DOI 10.1242/jcs.258495, PubMed 34109410
  114. Eide PW, Moosavi SH, Eilertsen IA, Brunsell TH, Langerud J, Berg KCG, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA, Sveen A (2021)
    Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
    NPJ Genom Med, 6 (1), 59
    DOI 10.1038/s41525-021-00223-7, PubMed 34262039
  115. Gonçalves AB, Hasselbalch SK, Joensen BB, Patzke S, Martens P, Ohlsen SK, Quinodoz M, Nikopoulos K, Suleiman R, Damsø Jeppesen MP, Weiss C, Christensen ST, Rivolta C, Andersen JS, Farinelli P, Pedersen LB (2021)
    CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
    Elife, 10
    DOI 10.7554/eLife.63731, PubMed 34259627
  116. Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M (2021)
    The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
    Proc Natl Acad Sci U S A, 118 (28)
    DOI 10.1073/pnas.2024596118, PubMed 34244439
  117. Wang T, Szedmak S, Wang H, Aittokallio T, Pahikkala T, Cichonska A, Rousu J (2021)
    Modeling drug combination effects via latent tensor reconstruction
    Bioinformatics, 37 (Suppl_1), i93-i101
    DOI 10.1093/bioinformatics/btab308, PubMed 34252952
  118. Rye IH, Huse K, Josefsson SE, Kildal W, Danielsen HE, Schlichting E, Garred Ø, Riis ML, Osbreac, Lingjaerde OC, Myklebust JH, Russnes HG (2021)
    Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
    Mol Oncol, 16 (1), 88-103
    DOI 10.1002/1878-0261.13047, PubMed 34165864
  119. Jøntvedt Jørgensen M, Nore KG, Aass HCD, Layre E, Nigou J, Mortensen R, Tasken K, Kvale D, Jenum S, Tonby K, Dyrhol-Riise AM (2021)
    Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
    Front Cell Infect Microbiol, 11, 669623
    DOI 10.3389/fcimb.2021.669623, PubMed 34307194
  120. Ellingsen EB, Mangsbo SM, Hovig E, Gaudernack G (2021)
    Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
    Front Immunol, 12, 682492
    DOI 10.3389/fimmu.2021.682492, PubMed 34290704
  121. Sioud M, Juzenas P, Zhang Q, Kleinauskas A, Peng Q (2021)
    Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
    Cancers (Basel), 13 (13)
    DOI 10.3390/cancers13133356, PubMed 34283089
  122. Kukkonen K, Taavitsainen S, Huhtala L, Uusi-Makela J, Granberg KJ, Nykter M, Urbanucci A (2021)
    Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response
    Cancers (Basel), 13 (13)
    DOI 10.3390/cancers13133325, PubMed 34283056
  123. Andersen E, Chollet ME, Bernardi F, Branchini A, Baroni M, Mariani G, Dolce A, Batorova A, Skarpen E, Myklebust CF, Skretting G, Sandset PM (2021)
    The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones
    Appl. Sci.-Basel, 11 (13), 5762
    DOI 10.3390/app11135762
  124. Tan KW (2021)
    First person - Kia Wee Tan
    J. Cell Sci., 134 (14), jcs259055
    DOI 10.1242/jcs.259055
  125. Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
    iScience, 24 (7), 102807
    DOI 10.1016/j.isci.2021.102807, PubMed 34337362
  126. Guerriero I, Ramberg H, Sagini K, Ramirez-Garrastacho M, Taskén KA, Llorente A (2021)
    Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
    PLoS One, 16 (6), e0253828
    DOI 10.1371/journal.pone.0253828, PubMed 34191854
  127. He C, Micallef L, He L, Peddinti G, Aittokallio T, Jacucci G (2021)
    Characterizing the Quality of Insight by Interactions: A Case Study
    IEEE Trans Vis Comput Graph, 27 (8), 3410-3424
    DOI 10.1109/TVCG.2020.2977634, PubMed 32142444
  128. Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N et al. (2021)
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
    Cell Rep, 35 (13), 109291
    DOI 10.1016/j.celrep.2021.109291, PubMed 34192548
  129. Nguyen L, Madsen SJ, Berg K, Hirschberg H (2021)
    An improved in vitro photochemical internalization protocol for 3D spheroid cultures
    Lasers Med Sci, 36 (8), 1567-1571
    DOI 10.1007/s10103-021-03332-y, PubMed 34185168
  130. Dominguez-Valentin M, Plazzer JP, Sampson JR, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Macrae F, Winship IM, Thomas H, Evans DG, Burn J, Greenblatt M, de Vos Tot Nederveen Cappel WH, Sijmons RH, Nielsen M, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Lindblom A, Valle AD et al. (2021)
    No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
    J Clin Med, 10 (13)
    DOI 10.3390/jcm10132856, PubMed 34203177
  131. Guldvik IJ, Ekseth L, Kishan AU, Stensvold A, Inderberg EM, Lilleby W (2021)
    Circulating Tumor Cell Persistence Associates with Long-Term Clinical Outcome to a Therapeutic Cancer Vaccine in Prostate Cancer
    J Pers Med, 11 (7)
    DOI 10.3390/jpm11070605, PubMed 34206815
  132. Baxter JS, Johnson N, Tomczyk K, Gillespie A, Maguire S, Brough R, Fachal L, Michailidou K, Bolla MK, Wang Q, Dennis J, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE et al. (2021)
    Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
    Am J Hum Genet, 108 (7), 1190-1203
    DOI 10.1016/j.ajhg.2021.05.013, PubMed 34146516
  133. Dillard P, Casey N, Pollmann S, Vernhoff P, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2021)
    Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
    Oncoimmunology, 10 (1), 1936757
    DOI 10.1080/2162402X.2021.1936757, PubMed 34235003
  134. Spasevska I, Myklebust JH (2021)
    What It Takes to Transform a T Cell
    Cancer Res, 81 (12), 3160-3161
    DOI 10.1158/0008-5472.CAN-21-0784, PubMed 34224376
  135. Nunes-Xavier CE, Kildal W, Kleppe A, Danielsen HE, Waehre H, Llarena R, Maelandsmo GM, Fodstad Ø, Pulido R, López JI (2021)
    Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
    Prostate, 81 (12), 838-848
    DOI 10.1002/pros.24180, PubMed 34125445
  136. Lesueur F, Easton DF, Renault AL, Tavtigian SV, Bernstein JL, Kote-Jarai Z, Eeles RA, Plaseska-Karanfia D, Feliubadaló L, Spanish ATM working group, Arun B, Herold N, Versmold B, Schmutzler RK, GC-HBOC, Nguyen-Dumont T, Southey MC, Dorling L, Dunning AM, Ghiorzo P, Dalmasso BS, Cavaciuti E, Le Gal D, Roberts NJ, Dominguez-Valentin M et al. (2021)
    First international workshop of the ATM and cancer risk group (4-5 December 2019)
    Fam Cancer
    DOI 10.1007/s10689-021-00248-y, PubMed 34125377
  137. Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J (2021)
    Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
    Cells, 10 (6)
    DOI 10.3390/cells10061476, PubMed 34204611
  138. Nowosielska EM, Cheda A, Pociegiel M, Cheda L, Szymański P, Wiedlocha A (2021)
    Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
    Int J Mol Sci, 22 (12)
    DOI 10.3390/ijms22126309, PubMed 34208396
  139. Lachota M, Lennikov A, Malmberg KJ, Zagozdzon R (2021)
    Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression
    J Immunol Res, 2021, 9920234
    DOI 10.1155/2021/9920234, PubMed 34195299
  140. Fløisand Y, Schroeder MA, Chevallier P, Selleslag D, Devine S, Renteria AS, Mohty M, Yakoub-Agha I, Chen C, Parfionovas A, Quadri S, Jansson J, Akbari M, Chen YB (2021)
    A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
    Bone Marrow Transplant, 56 (10), 2477-2488
    DOI 10.1038/s41409-021-01356-0, PubMed 34108672
  141. Dagenborg VJ, Marshall SE, Grzyb K, Fretland ÅA, Lund-Iversen M, Mælandsmo GM, Ree AH, Edwin B, Yaqub S, Flatmark K (2021)
    Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
    Front Oncol, 11, 671629
    DOI 10.3389/fonc.2021.671629, PubMed 34178659
  142. Toutah K, Nawar N, Timonen S, Sorger H, Raouf YS, Bukhari S, von Jan J, Ianevski A, Gawel JM, Olaoye OO, Geletu M, Abdeldayem A, Israelian J, Radu TB, Sedighi A, Bhatti MN, Hassan MM, Manaswiyoungkul P, Shouksmith AE, Neubauer HA, de Araujo ED, Aittokallio T, Krämer OH, Moriggl R, Mustjoki S et al. (2021)
    Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia
    J Med Chem, 64 (12), 8486-8509
    DOI 10.1021/acs.jmedchem.1c00420, PubMed 34101461
  143. Janiszewska M, Stein S, Metzger Filho O, Eng J, Kingston NL, Harper NW, Rye IH, Alečković M, Trinh A, Murphy KC, Marangoni E, Cristea S, Oakes B, Winer EP, Krop IE, Russnes HG, Spellman PT, Bucher E, Hu Z, Chin K, Gray JW, Michor F, Polyak K (2021)
    The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer
    JCI Insight, 6 (11)
    DOI 10.1172/jci.insight.147617, PubMed 33886505
  144. Andersson Y, Fleten KG, Abrahamsen TW, Reed W, Davidson B, Flatmark K (2021)
    Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
    Cancers (Basel), 13 (11)
    DOI 10.3390/cancers13112819, PubMed 34198773
  145. Karvelsson ST, Sigurdsson A, Seip K, Grinde MT, Wang Q, Johannsson F, Mælandsmo GM, Moestue SA, Rolfsson O, Halldorsson S (2021)
    EMT-Derived Alterations in Glutamine Metabolism Sensitize Mesenchymal Breast Cells to mTOR Inhibition
    Mol Cancer Res, 19 (9), 1546-1558
    DOI 10.1158/1541-7786.MCR-20-0962, PubMed 34088869
  146. Rudolph MJ, Poon AY, Kavaliauskiene S, Myrann AG, Reynolds-Peterson C, Davis SA, Sandvig K, Vance DJ, Mantis NJ (2021)
    Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface
    J Mol Biol, 433 (15), 167086
    DOI 10.1016/j.jmb.2021.167086, PubMed 34089718
  147. Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM, IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G et al. (2021)
    Crowdsourced mapping of unexplored target space of kinase inhibitors
    Nat Commun, 12 (1), 3307
    DOI 10.1038/s41467-021-23165-1, PubMed 34083538
  148. Xu H, Lien T, Bergholtz H, Fleischer T, Djerroudi L, Vincent-Salomon A, Sørlie T, Aittokallio T (2021)
    Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression
    Front Genet, 12, 670749
    DOI 10.3389/fgene.2021.670749, PubMed 34149812
  149. Kidd SG, Carm KT, Bogaard M, Olsen LG, Bakken AC, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2021)
    High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
    Neoplasia, 23 (6), 634-641
    DOI 10.1016/j.neo.2021.05.012, PubMed 34107378
  150. Waldeland JO, Gaustad JV, Rofstad EK, Evje S (2021)
    In silico investigations of intratumoral heterogeneous interstitial fluid pressure
    J Theor Biol, 526, 110787
    DOI 10.1016/j.jtbi.2021.110787, PubMed 34087266
  151. Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å (2021)
    NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
    J Transl Med, 19 (1), 232
    DOI 10.1186/s12967-021-02905-3, PubMed 34059094
  152. Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
    Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
    Cells, 10 (6)
    DOI 10.3390/cells10061342, PubMed 34071546
  153. Øverbye A, Torgersen ML, Sønstevold T, Iversen TG, Mørch Ý, Skotland T, Sandvig K (2021)
    Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: toxicity and changes in the proteome of breast, colon and prostate cancer cells
    Nanotoxicology, 15 (7), 865-884
    DOI 10.1080/17435390.2021.1924888, PubMed 34047629
  154. Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
    Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
    Carcinogenesis, 42 (5), 685-693
    DOI 10.1093/carcin/bgab015, PubMed 33609362
  155. Peneder P, Stütz AM, Surdez D, Krumbholz M, Semper S, Chicard M, Sheffield NC, Pierron G, Lapouble E, Tötzl M, Ergüner B, Barreca D, Rendeiro AF, Agaimy A, Boztug H, Engstler G, Dworzak M, Bernkopf M, Taschner-Mandl S, Ambros IM, Myklebost O, Marec-Bérard P, Burchill SA, Brennan B, Strauss SJ et al. (2021)
    Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
    Nat Commun, 12 (1), 3230
    DOI 10.1038/s41467-021-23445-w, PubMed 34050156
  156. Seppälä TT, Latchford A, Negoi I, Sampaio Soares A, Jimenez-Rodriguez R, Sánchez-Guillén L, Evans DG, Ryan N, Crosbie EJ, Dominguez-Valentin M, Burn J, Kloor M, Knebel Doeberitz MV, Duijnhoven FJBV, Quirke P, Sampson JR, Møller P, Möslein G, European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) (2021)
    European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
    Br J Surg, 108 (5), 484-498
    DOI 10.1002/bjs.11902, PubMed 34043773
  157. Wirth M, Mouilleron S, Zhang W, Sjøttem E, Abudu YP, Jain A, Olsvik HL, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
    Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    J Mol Biol, 433 (15), 167049
    DOI 10.1016/j.jmb.2021.167049, PubMed 34052024
  158. Sandvig K, Kavaliauskiene S, Skotland T (2021)
    The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
    Toxins (Basel), 13 (6)
    DOI 10.3390/toxins13060377, PubMed 34070659
  159. Normann LS, Aure MR, Leivonen SK, Haugen MH, Hongisto V, Kristensen VN, Mælandsmo GM, Sahlberg KK (2021)
    MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
    Sci Rep, 11 (1), 10893
    DOI 10.1038/s41598-021-90385-2, PubMed 34035375
  160. Berg J, Ramberg C, Haugstvedt JOS, Bengtson MB, Gabrielsen AM, Brustugun OT, Halvorsen AR, Helland Å (2021)
    Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers
    Front Oncol, 11, 674731
    DOI 10.3389/fonc.2021.674731, PubMed 34109123
  161. Lilleborge M, Falk RS, Sørlie T, Ursin G, Hofvind S (2021)
    Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion
    Int J Cancer, 149 (6), 1247-1256
    DOI 10.1002/ijc.33680, PubMed 33990967
  162. Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
    Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Ann Surg Oncol, 28 (9), 5252-5262
    DOI 10.1245/s10434-021-10022-0, PubMed 34019185
  163. Hamfjord J, Guren TK, Glimelius B, Sorbye H, Pfeiffer P, Dajani O, Lingjaerde OC, Tveit KM, Pallisgaard N, Spindler KG, Kure EH (2021)
    Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
    Int J Cancer, 149 (6), 1385-1397
    DOI 10.1002/ijc.33672, PubMed 33961700
  164. Gaustad JV, Rofstad EK (2021)
    Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI
    Front Oncol, 11, 668916
    DOI 10.3389/fonc.2021.668916, PubMed 34094964
  165. Eide M, Zhang X, Karlsen OA, Goldstone JV, Stegeman J, Jonassen I, Goksøyr A (2021)
    The chemical defensome of five model teleost fish
    Sci Rep, 11 (1), 10546
    DOI 10.1038/s41598-021-89948-0, PubMed 34006915
  166. Herring S, Oda JM, Wagoner J, Kirchmeier D, O'Connor A, Nelson EA, Huang Q, Liang Y, DeWald LE, Johansen LM, Glass PJ, Olinger GG, Ianevski A, Aittokallio T, Paine MF, Fink SL, White JM, Polyak SJ (2021)
    Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs"
    Antimicrob Agents Chemother, 65 (6)
    DOI 10.1128/AAC.00653-21, PubMed 34006613
  167. Mattingsdal M, Ebenesersdóttir SS, Moore KHS, Andreassen OA, Hansen TF, Werge T, Kockum I, Olsson T, Alfredsson L, Helgason A, Stefánsson K, Hovig E (2021)
    The genetic structure of Norway
    Eur J Hum Genet, 29 (11), 1710-1718
    DOI 10.1038/s41431-021-00899-6, PubMed 34002043
  168. Park J, Choi JY, Choi J, Chung S, Song N, Park SK, Han W, Noh DY, Ahn SH, Lee JW, Kim MK, Jee SH, Wen W, Bolla MK, Wang Q, Dennis J, Michailidou K, Shah M, Conroy DM, Harrington PA, Mayes R, Czene K, Hall P, Teras LR, Patel AV et al. (2021)
    Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
    Cancers (Basel), 13 (10)
    DOI 10.3390/cancers13102370, PubMed 34069208
  169. Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T (2021)
    V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
    Autophagy, 17 (12), 4442-4452
    DOI 10.1080/15548627.2021.1918915, PubMed 33978540
  170. Aamdal E, Inderberg EM, Ellingsen EB, Rasch W, Brunsvig PF, Aamdal S, Heintz KM, Vodák D, Nakken S, Hovig E, Nyakas M, Guren TK, Gaudernack G (2021)
    Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
    Front Immunol, 12, 663865
    DOI 10.3389/fimmu.2021.663865, PubMed 34046035
  171. Holland P, Hagopian WM, Jahren AH, Rusten TE (2021)
    Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
    BMC Biol, 19 (1), 85
    DOI 10.1186/s12915-021-01012-5, PubMed 33966633
  172. Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
    Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
    Acta Oncol, 60 (7), 921-930
    DOI 10.1080/0284186X.2021.1918763, PubMed 33966592
  173. Bjaanæs MM, Sande EPS, Loe Ø, Ramberg C, Næss TM, Ottestad A, Rogg LV, Svestad JG, Haakensen VD (2021)
    Improved adaptive radiotherapy to adjust for anatomical alterations during curative treatment for locally advanced lung cancer
    Phys Imaging Radiat Oncol, 18, 51-54
    DOI 10.1016/j.phro.2021.04.003, PubMed 34258408
  174. Maura F, Boyle EM, Rustad EH, Ashby C, Kaminetzky D, Bruno B, Braunstein M, Bauer M, Blaney P, Wang Y, Ghamlouch H, Williams L, Stoeckle J, Davies FE, Walker BA, Maclachlan K, Diamond B, Landgren O, Morgan GJ (2021)
    Chromothripsis as a pathogenic driver of multiple myeloma
    Semin Cell Dev Biol (in press)
    DOI 10.1016/j.semcdb.2021.04.014, PubMed 33958284
  175. Thorgersen EB, Flatmark K (2021)
    ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
    Ann Surg Oncol, 28 (9), 5263-5264
    DOI 10.1245/s10434-021-10036-8, PubMed 33939046
  176. Kehrloesser S, Oberst S, Westerhuis W, Wendler A, Wind A, Blaauwgeers H, Burrion JB, Nagy P, Saeter G, Gustafsson E, De Paoli P, Lovey J, Lombardo C, Philip T, de Valeriola D, Docter M, Boomsma F, Saghatchian M, Svoboda M, Philip I, Monetti F, Hummel H, McVie G, Otter R, van Harten W (2021)
    Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks
    Mol. Oncol., 15 (5), 1277-1288
    DOI 10.1002/1878-0261.12950
  177. Sharma A, Colonna G (2021)
    Correction to: System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
    Mol Diagn Ther, 25 (3), 387
    DOI 10.1007/s40291-021-00527-5, PubMed 33950420
  178. Erdbrügger U, Blijdorp CJ, Bijnsdorp IV, Borràs FE, Burger D, Bussolati B, Byrd JB, Clayton A, Dear JW, Falcón-Pérez JM, Grange C, Hill AF, Holthöfer H, Hoorn EJ, Jenster G, Jimenez CR, Junker K, Klein J, Knepper MA, Koritzinsky EH, Luther JM, Lenassi M, Leivo J, Mertens I, Musante L et al. (2021)
    Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
    J Extracell Vesicles, 10 (7), e12093
    DOI 10.1002/jev2.12093, PubMed 34035881
  179. Sioud M (2021)
    Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
    EBioMedicine, 67, 103351
    DOI 10.1016/j.ebiom.2021.103351, PubMed 33965875
  180. Stenberg VY, Larsen RH, Ma LW, Peng Q, Juzenas P, Bruland ØS, Juzeniene A (2021)
    Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer
    Int J Mol Sci, 22 (9)
    DOI 10.3390/ijms22094815, PubMed 34062920
  181. Barkovskaya A, Goodwin CM, Seip K, Hilmarsdottir B, Pettersen S, Stalnecker C, Engebraaten O, Briem E, Der CJ, Moestue SA, Gudjonsson T, Maelandsmo GM, Prasmickaite L (2021)
    Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
    Mol Oncol, 15 (8), 2026-2045
    DOI 10.1002/1878-0261.12951, PubMed 33759347
  182. Quiles-Jimenez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygard S, Scheffler K, Prins J, Van der Veer E, Ogaard JDS, Floisand Y, Jorgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
    DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
    Atherosclerosis, 324, 123-132
    DOI 10.1016/j.atherosclerosis.2021.02.023
  183. Aure MR, Fleischer T, Bjørklund S, Ankill J, Castro-Mondragon JA, OSBREAC, Børresen-Dale AL, Tost J, Sahlberg KK, Mathelier A, Tekpli X, Kristensen VN (2021)
    Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
    Genome Med, 13 (1), 72
    DOI 10.1186/s13073-021-00880-4, PubMed 33926515
  184. Li RG, Lindland K, Tonstad SK, Bønsdorff TB, Juzeniene A, Westrøm S, Larsen RH (2021)
    Improved Formulation of 224Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP
    Pharmaceutics, 13 (5)
    DOI 10.3390/pharmaceutics13050634, PubMed 33946852
  185. Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
    Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
    Nanomaterials (Basel), 11 (5)
    DOI 10.3390/nano11051140, PubMed 33924869
  186. Mariathasan AB, Boye K, Dueland S, Flatmark K, Larsen SG (2021)
    Metastases in locally advanced rectal cancer undergoing curatively intended treatment
    Eur J Surg Oncol, 47 (9), 2377-2383
    DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768
  187. Schläfli AM, Tokarchuk I, Parejo S, Jutzi S, Berezowska S, Engedal N, Tschan MP (2021)
    ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
    Sci Rep, 11 (1), 9011
    DOI 10.1038/s41598-021-87966-6, PubMed 33907223
  188. Hovda T, Hoff SR, Larsen M, Romundstad L, Sahlberg KK, Hofvind S (2021)
    True and Missed Interval Cancer in Organized Mammographic Screening: A Retrospective Review Study of Diagnostic and Prior Screening Mammograms
    Acad Radiol (in press)
    DOI 10.1016/j.acra.2021.03.022, PubMed 33926794
  189. Cangiano M, Grudniewska M, Salji MJ, Nykter M, Jenster G, Urbanucci A, Granchi Z, Janssen B, Hamilton G, Leung HY, Beumer IJ (2021)
    Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
    Cancers (Basel), 13 (9)
    DOI 10.3390/cancers13092094, PubMed 33925994
  190. Wirth M, Mouilleron S, Zhang W, Sjøttem E, Princely Abudu Y, Jain A, Lauritz Olsvik H, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
    Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    J Mol Biol, 433 (13), 166987
    DOI 10.1016/j.jmb.2021.166987, PubMed 33845085
  191. Sullivan LC, Nguyen THO, Harpur CM, Stankovic S, Kanagarajah AR, Koutsakos M, Saunders PM, Cai Z, Gray JA, Widjaja JML, Lin J, Pietra G, Mingari MC, Moretta L, Samir J, Luciani F, Westall GP, Malmberg KJ, Kedzierska K, Brooks AG (2021)
    Natural killer cell receptors regulate responses of HLA-E-restricted T cells
    Sci Immunol, 6 (58)
    DOI 10.1126/sciimmunol.abe9057, PubMed 33893172
  192. Nakken S, Lilleby W, Switlyk MD, Knudsen KE, Lilleby O, Zhao S, Kaveh F, Ekstrøm PO, Urbanucci A, Hovig E (2021)
    The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
    J Pers Med, 11 (5)
    DOI 10.3390/jpm11050330, PubMed 33922147
  193. Caulier B, Enserink JM, Wälchli S (2021)
    Pharmacologic Control of CAR T Cells
    Int J Mol Sci, 22 (9)
    DOI 10.3390/ijms22094320, PubMed 33919245
  194. Hauge S, Eek Mariampillai A, Rødland GE, Bay LTE, Landsverk HB, Syljuåsen RG (2021)
    Expanding roles of cell cycle checkpoint inhibitors in radiation oncology
    Int J Radiat Biol
    DOI 10.1080/09553002.2021.1913529, PubMed 33877959
  195. Landsverk HB, Sandquist LE, Bay LTE, Syljuåsen RG (2021)
    New link between the RNA polymerase II-CTD and replication stress
    Mol Cell Oncol, 8 (3), 1910008
    DOI 10.1080/23723556.2021.1910008, PubMed 34027044
  196. Skotland T, Iversen TG, Sandvig K (2021)
    Cellular uptake of nanoparticles: Involvement of caveolae?
    Precis Nanomed, 4 (2), 782-786
    DOI 10.33218/001c.22201, PublikaID 365
  197. Kosanović M, Llorente A, Glamočlija S, Valdivielso JM, Bozic M (2021)
    Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
    Int J Mol Sci, 22 (8)
    DOI 10.3390/ijms22083887, PubMed 33918699
  198. Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH (2021)
    The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
    Br J Cancer, 125 (2), 240-246
    DOI 10.1038/s41416-021-01377-y, PubMed 33837301
  199. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
    Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
    Clin Exp Metastasis, 38 (2), 253
    DOI 10.1007/s10585-021-10084-0, PubMed 33649933
  200. Lund-Andersen C, Torgunrud A, Fleten KG, Flatmark K (2021)
    Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
    J Gastrointest Oncol, 12 (Suppl 1), S191-S203
    DOI 10.21037/jgo-20-136, PubMed 33968437
  201. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2021)
    Correction to: Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 119
    DOI 10.1007/s10689-021-00246-0, PubMed 33792829
  202. Gundersen S, Boddu S, Capella-Gutierrez S, Drabløs F, Fernández JM, Kompova R, Taylor K, Titov D, Zerbino D, Hovig E (2021)
    Recommendations for the FAIRification of genomic track metadata
    F1000Res, 10
    DOI 10.12688/f1000research.28449.1, PubMed 34249331
  203. Ferreira FA, Helmersen K, Visnovska T, Jørgensen SB, Aamot HV (2021)
    Rapid nanopore-based DNA sequencing protocol of antibiotic-resistant bacteria for use in surveillance and outbreak investigation
    Microb Genom, 7 (4)
    DOI 10.1099/mgen.0.000557, PubMed 33885360
  204. Maagdenberg H, Oosterom N, Zanen J, Gemmati D, Windsor RE, Heil SG, Esperón P, Jabeen S, Ruiz-Argüelles GJ, Zolk O, Hoerning S, Sleurs C, Lopéz-Lopéz E, Moreno-Galván M, van den Heuvel-Eibrink MM, Maitland-van der Zee AH, Carleton BC (2021)
    Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis
    Crit Rev Oncol Hematol, 161, 103312
    DOI 10.1016/j.critrevonc.2021.103312, PubMed 33794308
  205. Rustad EH, Nadeu F, Angelopoulos N, Ziccheddu B, Bolli N, Puente XS, Campo E, Landgren O, Maura F (2021)
    mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
    Commun Biol, 4 (1), 424
    DOI 10.1038/s42003-021-01938-0, PubMed 33782531
  206. Johannesen TB, Smeland S, Aaserud S, Buanes EA, Skog A, Ursin G, Helland Å (2021)
    COVID-19 in Cancer Patients, Risk Factors for Disease and Adverse Outcome, a Population-Based Study From Norway
    Front Oncol, 11, 652535
    DOI 10.3389/fonc.2021.652535, PubMed 33842366
  207. Remberger M, Tjønnfjord GE, Abrahamsen IW, Ali M, Myhre AE, Gedde-Dahl T, Fløisand Y (2021)
    Superior Graft-versus-Host Disease-Free Relapse-Free Survival in Matched Unrelated Donor Hematopoietic Stem Cell Transplantation with Anti-Thymocyte Globulin (ATG) Compared to Matched Related Donor without ATG
    Transplant Cell Ther, 27 (7), 621.e1-621.e3
    DOI 10.1016/j.jtct.2021.03.019, PubMed 33895156
  208. Fleten KG, Eksteen JJ, Mauseth B, Camilio KA, Vasskog T, Sveinbjørnsson B, Rekdal Ø, Mælandsmo GM, Flatmark K (2021)
    Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
    Sci Rep, 11 (1), 6731
    DOI 10.1038/s41598-021-86239-6, PubMed 33762676
  209. Brück OE, Lallukka-Brück SE, Hohtari HR, Ianevski A, Ebeling FT, Kovanen PE, Kytölä SI, Aittokallio TA, Ramos PM, Porkka KV, Mustjoki SM (2021)
    Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS
    Blood Cancer Discov, 2 (3), 238-249
    DOI 10.1158/2643-3230.BCD-20-0162, PubMed 34661156
  210. Brück OE, Lallukka-Brück SE, Hohtari HR, Ianevski A, Ebeling FT, Kovanen PE, Kytölä SI, Aittokallio TA, Ramos PM, Porkka KV, Mustjoki SM (2021)
    Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS
    Blood Cancer Discov, 2 (3), 238-249
    DOI 10.1158/2643-3230.BCD-20-0162, PubMed 35015673
  211. Ree AH (2021)
    Precision cancer medicine - still expedient for the few
    Tidsskr Nor Laegeforen, 141 (5)
    DOI 10.4045/tidsskr.20.0980, PubMed 33754663
  212. Georgiesh T, Namløs HM, Sharma N, Lorenz S, Myklebost O, Bjerkehagen B, Meza-Zepeda LA, Boye K (2021)
    Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
    Pathology, 53 (6), 713-719
    DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702
  213. Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N (2021)
    Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
    Thromb Haemost, 121 (12), 1588-1598
    DOI 10.1055/a-1450-8568, PubMed 33742435
  214. Herring S, Oda JM, Wagoner J, Kirchmeier D, O'Connor A, Nelson EA, Huang Q, Liang Y, DeWald LE, Johansen LM, Glass PJ, Olinger GG, Ianevski A, Aittokallio T, Paine MF, Fink SL, White JM, Polyak SJ (2021)
    Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs
    Antimicrob Agents Chemother, 65 (4)
    DOI 10.1128/AAC.01146-20, PubMed 33468464
  215. Oksvold MP, Berglund UW, Gad H, Bai BY, Stokke T, Rein ID, Pham T, Sanjiv K, Oy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Vatsveen TK (2021)
    Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
    Sci Rep, 11 (1), 6317
    DOI 10.1038/s41598-021-85613-8
  216. Stabell M, Sæther T, Røhr ÅK, Gabrielsen OS, Myklebost O (2021)
    Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
    Biochem Biophys Res Commun, 552, 91-97
    DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765
  217. Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
    Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Eur J Cancer, 148, 124-133
    DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
  218. Kjosen G, Rydenfelt K, Horneland R, Aandahl EM, Line PD, Dorenberg E, Berstad AE, Brabrand K, Hagen G, Pischke SE, Bergmann GB, Nordheim E, Jenssen TG, Tonnessen TI, Haugaa H (2021)
    Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
    PLoS One, 16 (3), e0247615
    DOI 10.1371/journal.pone.0247615
  219. Langenbucher A, Bowen D, Sakhtemani R, Bournique E, Wise JF, Zou L, Bhagwat AS, Buisson R, Lawrence MS (2021)
    An extended APOBEC3A mutation signature in cancer
    Nat. Commun., 12 (1), 1602
    DOI 10.1038/s41467-021-21891-0
  220. Grad I, Hanes R, Ayuda-Duran P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
    Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
    PLoS One, 16 (3), e0248140
    DOI 10.1371/journal.pone.0248140
  221. Napoli E, Bønsdorff TB, Jorstad IS, Bruland ØS, Larsen RH, Westrøm S (2021)
    Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use
    PLoS One, 16 (3), e0248133
    DOI 10.1371/journal.pone.0248133, PubMed 33662039
  222. Lone AM, Taskén K (2021)
    Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
    Mol Pharmacol, 99 (5), 370-382
    DOI 10.1124/molpharm.120.000170, PubMed 33674363
  223. Hølmebakk T, Wiedswang AM, Meza-Zepeda LA, Hompland I, Lobmaier IVK, Berner JM, Stoldt S, Boye K (2021)
    Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
    Ann Surg Oncol, 28 (11), 6837-6845
    DOI 10.1245/s10434-021-09605-8, PubMed 33651216
  224. Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
    Sealing holes in cellular membranes
    EMBO J, 40 (7), e106922
    DOI 10.15252/embj.2020106922, PubMed 33644904
  225. Jaiswal A, Gautam P, Pietilä EA, Timonen S, Nordström N, Akimov Y, Sipari N, Tanoli Z, Fleischer T, Lehti K, Wennerberg K, Aittokallio T (2021)
    Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
    Mol Syst Biol, 17 (3), e9526
    DOI 10.15252/msb.20209526, PubMed 33750001
  226. Luna S, Torices L, Mingo J, Amo L, Rodríguez-Escudero I, Ruiz-Ibarlucea P, Erramuzpe A, Cortés JM, Tejada MI, Molina M, Nunes-Xavier CE, López JI, Cid VJ, Pulido R (2021)
    A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
    Hum Mutat, 42 (5), 551-566
    DOI 10.1002/humu.24186, PubMed 33600059
  227. Helwa R, Gansmo LB, Bjørnslett M, Halle MK, Werner HMJ, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
    Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
    Biomarkers, 26 (4), 302-308
    DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
  228. Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
    Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
    Autophagy, 17 (4), 1046-1048
    DOI 10.1080/15548627.2021.1887548, PubMed 33629888
  229. Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
    Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
    Sci Rep, 11 (1), 4613
    DOI 10.1038/s41598-021-84268-9, PubMed 33633289
  230. Akimov Y, Aittokallio T (2021)
    Re-defining synthetic lethality by phenotypic profiling for precision oncology
    Cell Chem Biol, 28 (3), 246-256
    DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125
  231. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
    A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
    Sci Transl Med, 13 (582)
    DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
  232. Siddiqui FA, Parkkola H, Vukic V, Oetken-Lindholm C, Jaiswal A, Kiriazis A, Pavic K, Aittokallio T, Salminen TA, Abankwa D (2021)
    Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling
    Cancers (Basel), 13 (4)
    DOI 10.3390/cancers13040927, PubMed 33672199
  233. Gaustad JV, Simonsen TG, Hansem LMK, Rofstad EK (2021)
    Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
    Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
    DOI 10.1007/s00259-021-05243-0, PubMed 33606081
  234. Juzeniene A, Stenberg VY, Bruland ØS, Larsen RH (2021)
    Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
    Cancers (Basel), 13 (4)
    DOI 10.3390/cancers13040779, PubMed 33668474
  235. Ask EH, Tschan-Plessl A, Gjerdingen TJ, Saetersmoen ML, Hoel HJ, Wiiger MT, Olweus J, Wahlin BE, Lingjaerde OC, Horowitz A, Cashen AF, Watkins M, Fehniger TA, Holte H, Kolstad A, Malmberg KJ (2021)
    A Systemic Protein Deviation Score Linked to PD-1(+) CD8(+) T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma
    Med, 2 (2), 180-+
    DOI 10.1016/j.medj.2020.10.006
  236. Tanoli Z, Vähä-Koskela M, Aittokallio T (2021)
    Artificial intelligence, machine learning, and drug repurposing in cancer
    Expert Opin Drug Discov, 16 (9), 977-989
    DOI 10.1080/17460441.2021.1883585, PubMed 33543671
  237. Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
    Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
    Cancer Immunol Immunother, 70 (9), 2617-2624
    DOI 10.1007/s00262-021-02876-w, PubMed 33580363
  238. Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
    The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
    J Cell Sci, 134 (3)
    DOI 10.1242/jcs.250670, PubMed 33468622
  239. Ben-Elazar S, Aure MR, Jonsdottir K, Leivonen SK, Kristensen VN, Janssen EAM, Kleivi Sahlberg K, Lingjærde OC, Yakhini Z (2021)
    miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
    PLoS Comput Biol, 17 (2), e1008608
    DOI 10.1371/journal.pcbi.1008608, PubMed 33566819
  240. Krüger K, Silwal-Pandit L, Wik E, Straume O, Stefansson IM, Borgen E, Garred Ø, Naume B, Engebraaten O, Akslen LA (2021)
    Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
    Sci Rep, 11 (1), 3388
    DOI 10.1038/s41598-021-81914-0, PubMed 33564016
  241. Davydova E, Shimazu T, Schuhmacher MK, Jakobsson ME, Willemen HLDM, Liu T, Moen A, Ho AYY, Małecki J, Schroer L, Pinto R, Suzuki T, Grønsberg IA, Sohtome Y, Akakabe M, Weirich S, Kikuchi M, Olsen JV, Dohmae N, Umehara T, Sodeoka M, Siino V, McDonough MA, Eijkelkamp N, Schofield CJ et al. (2021)
    The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
    Nat Commun, 12 (1), 891
    DOI 10.1038/s41467-020-20670-7, PubMed 33563959
  242. Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
    Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
    FEBS Open Bio, 11 (3), 724-740
    DOI 10.1002/2211-5463.13098, PubMed 33512765
  243. Gorgen A, Guttormsen M, Larsen AC, Siem S, Adli E, Edin NFJ, Gjersdal H, Henriksen G, Malinen E, Modamio V, Schoultz B, Sobas PA, Theodossiou TA, Wikne JC (2021)
    The Oslo Cyclotron Laboratory
    Eur. Phys. J. Plus, 136 (2), 181
    DOI 10.1140/epjp/s13360-021-01150-3
  244. Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
    Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
    Int J Environ Res Public Health, 18 (4)
    DOI 10.3390/ijerph18041470, PubMed 33557277
  245. Berishvili E, Kaiser L, Cohen M, Berney T, Scholz H, Floisand Y, Mattsson J (2021)
    Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
    Stem Cell Rev Rep, 17 (1), 63-70
    DOI 10.1007/s12015-020-10004-x, PubMed 32696426
  246. Skotland T, Sandvig K (2021)
    Transport of nanoparticles across the endothelial cell layer
    Nano Today, 36, 101029
    DOI 10.1016/j.nantod.2020.101029
  247. Johansson ALV, Trewin CB, Fredriksson I, Reinertsen KV, Russnes H, Ursin G (2021)
    In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study
    Breast Cancer Res, 23 (1), 17
    DOI 10.1186/s13058-021-01393-z, PubMed 33526044
  248. Ianevski A, Lahtela J, Javarappa KK, Sergeev P, Ghimire BR, Gautam P, Vähä-Koskela M, Turunen L, Linnavirta N, Kuusanmäki H, Kontro M, Porkka K, Heckman CA, Mattila P, Wennerberg K, Giri AK, Aittokallio T (2021)
    Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
    Sci Adv, 7 (8)
    DOI 10.1126/sciadv.abe4038, PubMed 33608276
  249. Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
    Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
    Toxins (Basel), 13 (2)
    DOI 10.3390/toxins13020102, PubMed 33573355
  250. Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
    FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
    Commun Biol, 4 (1), 127
    DOI 10.1038/s42003-021-01647-8, PubMed 33514811
  251. Sakurai M, Mori T, Kato K, Kanaya M, Mizuno S, Shiratori S, Wakayama T, Uchida N, Kobayashi H, Kubo K, Amano I, Ohta T, Miyazaki Y, Kanda J, Fukuda T, Atsuta Y, Kondo E, Adult Lymphoma Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT) (2021)
    Outcome of allogeneic hematopoietic stem cell transplantation for follicular lymphoma relapsing after autologous transplantation: analysis of the Japan Society for Hematopoietic Cell Transplantation
    Bone Marrow Transplant, 56 (6), 1462-1466
    DOI 10.1038/s41409-020-01192-8, PubMed 33514920
  252. Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
    Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
    JCO Precis Oncol, 5
    DOI 10.1200/PO.20.00086, PubMed 34036235
  253. Hompland T, Fjeldbo CS, Lyng H (2021)
    Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
    Cancers (Basel), 13 (3)
    DOI 10.3390/cancers13030499, PubMed 33525508
  254. Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
    MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
    Mol Genet Metab Rep, 26, 100710
    DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904
  255. Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
    Editorial: Genomic Colocalization and Enrichment Analyses
    Front Genet, 11, 617876
    DOI 10.3389/fgene.2020.617876, PubMed 33574832
  256. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
  257. Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
    Wetting regulates autophagy of phase-separated compartments and the cytosol
    Nature, 591 (7848), 142-146
    DOI 10.1038/s41586-020-2992-3, PubMed 33473217
  258. Breast Cancer Association Consortium, Dorling L, Carvalho S, Allen J, González-Neira A, Luccarini C, Wahlström C, Pooley KA, Parsons MT, Fortuno C, Wang Q, Bolla MK, Dennis J, Keeman R, Alonso MR, Álvarez N, Herraez B, Fernandez V, Núñez-Torres R, Osorio A, Valcich J, Li M, Törngren T, Harrington PA, Baynes C et al. (2021)
    Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
    N Engl J Med, 384 (5), 428-439
    DOI 10.1056/NEJMoa1913948, PubMed 33471991
  259. Galili B, Tekpli X, Kristensen VN, Yakhini Z (2021)
    Efficient gene expression signature for a breast cancer immuno-subtype
    PLoS One, 16 (1), e0245215
    DOI 10.1371/journal.pone.0245215, PubMed 33434192
  260. Skånland SS, Mato AR (2021)
    Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
    Blood Adv, 5 (1), 334-343
    DOI 10.1182/bloodadvances.2020003423, PubMed 33570649
  261. Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
    Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 187 (2), 515-523
    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
  262. Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
    Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
    Mol Oncol, 15 (4), 830-845
    DOI 10.1002/1878-0261.12885, PubMed 33325154
  263. Otterhaug T, Janetzki S, Welters MJP, Håkerud M, Nedberg AG, Edwards VT, Boekestijn S, Loof NM, Selbo PK, Olivecrona H, van der Burg SH, Høgset A (2021)
    Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
    Front Immunol, 11, 576756
    DOI 10.3389/fimmu.2020.576756, PubMed 33488576
  264. Terkelsen T, Pernemalm M, Gromov P, Børresen-Dale AL, Krogh A, Haakensen VD, Lethiö J, Papaleo E, Gromova I (2021)
    High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
    Mol Oncol, 15 (2), 429-461
    DOI 10.1002/1878-0261.12850, PubMed 33176066
  265. Sharma A, Colonna G (2021)
    System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
    Mol Diagn Ther, 25 (1), 9-27
    DOI 10.1007/s40291-020-00505-3, PubMed 33475988
  266. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  267. Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, Leusen J, Andersen JT (2021)
    Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
    mAbs, 13 (1), 1893888
    DOI 10.1080/19420862.2021.1893888
  268. Sioud M (2021)
    RNA Interference: Story and Mechanisms
    Methods Mol Biol, 2282, 1-15
    DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566
  269. Li RG, Napoli E, Jorstad IS, Bønsdorff TB, Juzeniene A, Bruland ØS, Larsen RH, Westrøm S (2021)
    Calcium Carbonate Microparticles as Carriers of 224Ra: Impact of Specific Activity in Mice with Intraperitoneal Ovarian Cancer
    Curr Radiopharm, 14 (2), 145-153
    DOI 10.2174/1874471013666201201102056, PubMed 33261548
  270. Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
    From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
    Prog Chem Org Nat Prod, 115, 59-114
    DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641

Publications 2020

  1. Bergeron DE, Collins SM, Pibida L, Cessna JT, Fitzgerald R, Zimmerman BE, Ivanov P, Keightley JD, Napoli E (2020)
    Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison
    Appl Radiat Isot, 170, 109572
    DOI 10.1016/j.apradiso.2020.109572, PubMed 33461017
  2. Pulkkinen OI, Gautam P, Mustonen V, Aittokallio T (2020)
    Multiobjective optimization identifies cancer-selective combination therapies
    PLoS Comput Biol, 16 (12), e1008538
    DOI 10.1371/journal.pcbi.1008538, PubMed 33370253
  3. Öjlert ÅK, Nebdal D, Lund-Iversen M, Åstrøm Ellefsen R, Brustugun OT, Gran JM, Halvorsen AR, Helland Å (2020)
    Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer - predictors of response and impact of previous radiotherapy
    Acta Oncol, 60 (2), 149-156
    DOI 10.1080/0284186X.2020.1854851, PubMed 33356733
  4. Graim K, Gorenshteyn D, Robinson DG, Carriero NJ, Cahill JA, Chakrabarti R, Goldschmidt MH, Durham AC, Funk J, Storey JD, Kristensen VN, Theesfeld CL, Sorenmo KU, Troyanskaya OG (2020)
    Modeling molecular development of breast cancer in canine mammary tumors
    Genome Res, 31 (2), 337-347
    DOI 10.1101/gr.256388.119, PubMed 33361113
  5. Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Karlstad Ø, Juzeniene A, Ghiasvand R, Larsen IK, Green AC, Veierød MB, Robsahm TE (2020)
    Use of Immunomodulating Drugs and Risk of Cutaneous Melanoma: A Nationwide Nested Case-Control Study
    Clin Epidemiol, 12, 1389-1401
    DOI 10.2147/CLEP.S269446, PubMed 33376408
  6. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
    A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
    J Biol Chem, 296, 100179
    DOI 10.1074/jbc.RA120.015285, PubMed 33303632
  7. Flatin BTB, Vedeld HM, Pinto R, Langerud J, Lind GE, Lothe RA, Sveen A, Jeanmougin M (2020)
    Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
    Int J Cancer, 148 (7), 1652-1657
    DOI 10.1002/ijc.33425, PubMed 33284993
  8. Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Körner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang X, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang W, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR et al. (2020)
    Anti-tumour immunity induces aberrant peptide presentation in melanoma
    Nature, 590 (7845), 332-337
    DOI 10.1038/s41586-020-03054-1, PubMed 33328638
  9. Jacomin AC, Gohel R, Hussain Z, Varga A, Maruzs T, Eddison M, Sica M, Jain A, Moffat KG, Johansen T, Jenny A, Juhasz G, Nezis IP (2020)
    Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
    Life Sci Alliance, 4 (2)
    DOI 10.26508/lsa.202000965, PubMed 33318080
  10. Lachota M, Vincenti M, Winiarska M, Boye K, Zagożdżon R, Malmberg KJ (2020)
    Prospects for NK Cell Therapy of Sarcoma
    Cancers (Basel), 12 (12)
    DOI 10.3390/cancers12123719, PubMed 33322371
  11. Castañeda-Zegarra S, Zhang Q, Alirezaylavasani A, Fernandez-Berrocal M, Yao R, Oksenych V (2020)
    Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
    Aging (Albany NY), 12 (23), 23578-23597
    DOI 10.18632/aging.202346, PubMed 33289702
  12. Köksal H, Dillard P, Juzeniene A, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2020)
    Combinatorial CAR design improves target restriction
    J Biol Chem, 296, 100116
    DOI 10.1074/jbc.RA120.016234, PubMed 33234592
  13. Refinetti P, Morgenthaler S, Thilly WG, Arstad C, Ekstrøm PO (2020)
    Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
    Front Oncol, 10, 523860
    DOI 10.3389/fonc.2020.523860, PubMed 33344219
  14. Julkunen H, Cichonska A, Gautam P, Szedmak S, Douat J, Pahikkala T, Aittokallio T, Rousu J (2020)
    Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects
    Nat Commun, 11 (1), 6136
    DOI 10.1038/s41467-020-19950-z, PubMed 33262326
  15. Landsverk HB, Sandquist LE, Bay LTE, Steurer B, Campsteijn C, Landsverk OJB, Marteijn JA, Petermann E, Trinkle-Mulcahy L, Syljuåsen RG (2020)
    WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
    Cell Rep, 33 (9), 108469
    DOI 10.1016/j.celrep.2020.108469, PubMed 33264625
  16. Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
    Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Genet Med, 23 (4), 705-712
    DOI 10.1038/s41436-020-01029-1, PubMed 33257847
  17. Tschan-Plessl A, Kalberer CP, Wieboldt R, Stern M, Siegler U, Wodnar-Filipowicz A, Gerull S, Halter J, Heim D, Tichelli A, Tsakiris DA, Malmberg KJ, Passweg JR, Bottos A (2020)
    Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma
    Cytotherapy, 23 (4), 329-338
    DOI 10.1016/j.jcyt.2020.09.009, PubMed 33268029
  18. Halvorsen AR, Haugen MH, Öjlert ÅK, Lund-Iversen M, Jørgensen L, Solberg S, Mælandsmo GM, Brustugun OT, Helland Å (2020)
    Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
    Front Oncol, 10, 590755
    DOI 10.3389/fonc.2020.590755, PubMed 33324562
  19. Wang T, Gautam P, Rousu J, Aittokallio T (2020)
    Systematic mapping of cancer cell target dependencies using high-throughput drug screening in triple-negative breast cancer
    Comput Struct Biotechnol J, 18, 3819-3832
    DOI 10.1016/j.csbj.2020.11.001, PubMed 33335681
  20. Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ (2020)
    Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
    EMBO J, 39 (24), e104948
    DOI 10.15252/embj.2020104948, PubMed 33226137
  21. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2020)
    HIV-infected immunological non-responders have colon-restricted gut mucosal immune dysfunction
    J Infect Dis (in press)
    DOI 10.1093/infdis/jiaa714, PubMed 33216130
  22. Zhao S, Agafonov O, Azab A, Stokowy T, Hovig E (2020)
    Accuracy and efficiency of germline variant calling pipelines for human genome data
    Sci Rep, 10 (1), 20222
    DOI 10.1038/s41598-020-77218-4, PubMed 33214604
  23. Dillard P, Köksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Mælandsmo GM, Flørenes VA, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
    Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
    Mol Ther, 29 (3), 1199-1213
    DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301
  24. Aghayan DL, Kazaryan AM, Dagenborg VJ, Røsok BI, Fagerland MW, Waaler Bjørnelv GM, Kristiansen R, Flatmark K, Fretland ÅA, Edwin B, OSLO-COMET Survival Study Collaborators (2020)
    Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
    Ann Intern Med, 174 (2), 175-182
    DOI 10.7326/M20-4011, PubMed 33197213
  25. Romena G, Nguyen L, Berg K, Madsen SJ, Hirschberg H (2020)
    Enhanced gene transfection of macrophages by photochemical internalization: Potential for gene-directed enzyme prodrug therapy of gliomas
    Photodiagnosis Photodyn Ther, 33, 102098
    DOI 10.1016/j.pdpdt.2020.102098, PubMed 33188941
  26. Kumar S, Jain A, Choi SW, Peixoto Duarte da Silva G, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB
    Autophagy, 16 (12), 2305-2306
    DOI 10.1080/15548627.2020.1837423, PubMed 33070669
  27. Liese S, Wenzel EM, Kjos I, Rojas Molina R, Schultz SW, Brech A, Stenmark H, Raiborg C, Carlson A (2020)
    Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
    Proc Natl Acad Sci U S A, 117 (46), 28614-28624
    DOI 10.1073/pnas.2014228117, PubMed 33139578
  28. Levy-Jurgenson A, Tekpli X, Kristensen VN, Yakhini Z (2020)
    Spatial transcriptomics inferred from pathology whole-slide images links tumor heterogeneity to survival in breast and lung cancer
    Sci Rep, 10 (1), 18802
    DOI 10.1038/s41598-020-75708-z, PubMed 33139755
  29. Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
    Author Correction: STEEP mediates STING ER exit and activation of signaling
    Nat Immunol, 21 (11), 1468-1469
    DOI 10.1038/s41590-020-0803-5, PubMed 32929276
  30. Bergsland CH, Bruun J, Guren MG, Svindland A, Bjørnslett M, Smeby J, Hektoen M, Kolberg M, Domingo E, Pellinen T, Tomlinson I, Kerr D, Church DN, Nesbakken A, Sveen A, Lothe RA (2020)
    Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
    ESMO Open, 5 (6), e001040
    DOI 10.1136/esmoopen-2020-001040, PubMed 33219056
  31. Epting D, Senaratne LDS, Ott E, Holmgren A, Sumathipala D, Larsen SM, Wallmeier J, Bracht D, Frikstad KM, Crowley S, Sikiric A, Barøy T, Käsmann-Kellner B, Decker E, Decker C, Bachmann N, Patzke S, Phelps IG, Katsanis N, Giles R, Schmidts M, Zucknick M, Lienkamp SS, Omran H, Davis EE et al. (2020)
    Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome
    Hum Mutat, 41 (12), 2179-2194
    DOI 10.1002/humu.24127, PubMed 33131181
  32. Nguyen L, Potma EO, Le JN, Johnson J, Romena G, Peng Q, Berg K, Hirschberg H (2020)
    Photosensitizer delivery by fibrin glue: potential for bypassing the blood-brain barrier
    Lasers Med Sci, 36 (5), 1031-1038
    DOI 10.1007/s10103-020-03140-w, PubMed 33123852
  33. Geier CB, Farmer JR, Foldvari Z, Ujhazi B, Steininger J, Sleasman JW, Parikh S, Dilley MA, Pai SY, Henderson L, Hazen M, Neven B, Moshous D, Sharapova SO, Mihailova S, Yankova P, Naumova E, Özen S, Byram K, Fernandez J, Wolf HM, Eibl MM, Notarangelo LD, Calabrese LH, Walter JE (2020)
    Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency
    Front Immunol, 11, 574738
    DOI 10.3389/fimmu.2020.574738, PubMed 33193364
  34. Kolapalli SP, Sahu R, Chauhan NR, Jena KK, Mehto S, Das SK, Jain A, Rout M, Dash R, Swain RK, Lee DY, Rusten TE, Chauhan S, Chauhan S (2020)
    RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
    Cancer Res, 81 (2), 315-331
    DOI 10.1158/0008-5472.CAN-20-1871, PubMed 33067265
  35. Jendryczko K, Chudzian J, Skinder N, Opaliński Ł, Rzeszótko J, Wiedlocha A, Otlewski J, Szlachcic A (2020)
    FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
    Cancers (Basel), 12 (10)
    DOI 10.3390/cancers12102992, PubMed 33076489
  36. Yu H, Brustugun OT, Ekman S, Botling J, La Fleur L, Micke P, Solberg S, Berglund A, Rivard C, Hirsch FR (2020)
    Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer
    Clin Lung Cancer, 22 (4), e555-e562
    DOI 10.1016/j.cllc.2020.09.018, PubMed 33214079
  37. Goldenson BH, Zhu H, Wang YM, Heragu N, Bernareggi D, Ruiz-Cisneros A, Bahena A, Ask EH, Hoel HJ, Malmberg KJ, Kaufman DS (2020)
    Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles
    Front Immunol, 11, 561553
    DOI 10.3389/fimmu.2020.561553, PubMed 33178188
  38. Guldvik IJ, Zuber V, Braadland PR, Grytli HH, Ramberg H, Lilleby W, Thiede B, Zucknick M, Saatcioglu F, Gislefoss R, Kvåle R, George A, Grönberg H, Wiklund F, Neal DE, Gnanapragasam VJ, Taskén KA, Mills IG (2020)
    Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
    Eur Urol Open Sci, 21, 51-60
    DOI 10.1016/j.euros.2020.08.007, PubMed 34337468
  39. Salgado D, Armean IM, Baudis M, Beltran S, Capella-Gutierrez S, Carvalho-Silva D, Dominguez Del Angel V, Dopazo J, Furlong LI, Gao B, Garcia L, Gerloff D, Gut I, Gyenesei A, Habermann N, Hancock JM, Hanauer M, Hovig E, Johansson LF, Keane T, Korbel J, Lauer KB, Laurie S, Leskošek B, Lloyd D et al. (2020)
    The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
    F1000Res, 9
    DOI 10.12688/f1000research.24887.1, PubMed 34367618
  40. Barkovskaya A, Seip K, Prasmickaite L, Mills IG, Moestue SA, Itkonen HM (2020)
    Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells
    Sci Rep, 10 (1), 16992
    DOI 10.1038/s41598-020-74083-z, PubMed 33046784
  41. Skånland SS, Karlsen L, Taskén K (2020)
    B cell signalling pathways-New targets for precision medicine in chronic lymphocytic leukaemia
    Scand J Immunol, 92 (5), e12931
    DOI 10.1111/sji.12931, PubMed 32640099
  42. Engelsen AST, Wnuk-Lipinska K, Bougnaud S, Pelissier Vatter FA, Tiron C, Villadsen R, Miyano M, Lotsberg ML, Madeleine N, Panahandeh P, Dhakal S, Tan TZ, Peters SD, Grøndal S, Aziz SM, Nord S, Herfindal L, Stampfer MR, Sørlie T, Brekken RA, Straume O, Halberg N, Gausdal G, Thiery JP, Akslen LA et al. (2020)
    AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer
    iScience, 23 (11), 101649
    DOI 10.1016/j.isci.2020.101649, PubMed 33103086
  43. Sioud M (2020)
    Microbial sensing by haematopoietic stem and progenitor cells: Vigilance against infections and immune education of myeloid cells
    Scand J Immunol, 92 (5), e12957
    DOI 10.1111/sji.12957, PubMed 32767789
  44. Jacobs B, Schlögl S, Strobl CD, Völkl S, Stoll A, Mougiakakos D, Malmberg KJ, Mackensen A, Aigner M (2020)
    The Oncometabolite 5'-Deoxy-5'-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation
    Front Immunol, 11, 2128
    DOI 10.3389/fimmu.2020.02128, PubMed 33123121
  45. Kramer I, Hooning MJ, Mavaddat N, Hauptmann M, Keeman R, Steyerberg EW, Giardiello D, Antoniou AC, Pharoah PDP, Canisius S, Abu-Ful Z, Andrulis IL, Anton-Culver H, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Brauch H et al. (2020)
    Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk
    Am J Hum Genet, 107 (5), 837-848
    DOI 10.1016/j.ajhg.2020.09.001, PubMed 33022221
  46. Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
    Nat Cell Biol, 22 (10), 1286
    DOI 10.1038/s41556-020-0574-0, PubMed 32788721
  47. Hovda T, Tsuruda K, Hoff SR, Sahlberg KK, Hofvind S (2020)
    Radiological review of prior screening mammograms of screen-detected breast cancer
    Eur Radiol, 31 (4), 2568-2579
    DOI 10.1007/s00330-020-07130-y, PubMed 33001307
  48. Piñero TA, Soukarieh O, Rolain M, Alvarez K, López-Köstner F, Torrezan GT, Carraro DM, De Oliveira Nascimento IL, Bomfim TF, Machado-Lopes TMB, Freitas JC, Toralles MB, Sandes KA, Rossi BM, Junior SA, Meira J, Dominguez-Valentin M, Møller P, Vaccaro CA, Martins A, Pavicic WH (2020)
    MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
    Fam Cancer, 19 (4), 323-336
    DOI 10.1007/s10689-020-00182-5, PubMed 32363481
  49. Tinholt M, Stavik B, Tekpli X, Garred Ø, Borgen E, Kristensen V, Sahlberg KK, Sandset PM, Iversen N (2020)
    Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
    Oncoimmunology, 9 (1), 1824644
    DOI 10.1080/2162402X.2020.1824644, PubMed 33457104
  50. Welsh JA, van der Pol E, Bettin BA, Carter DRF, Hendrix A, Lenassi M, Langlois MA, Llorente A, van de Nes AS, Nieuwland R, Tang V, Wang L, Witwer KW, Jones JC (2020)
    Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
    J Extracell Vesicles, 9 (1), 1816641
    DOI 10.1080/20013078.2020.1816641, PubMed 33062218
  51. Patel S, Malmberg KJ (2020)
    Preventing a shock to the system. Two-pore channel 1 negatively regulates anaphylaxis
    Cell Calcium, 92, 102289
    DOI 10.1016/j.ceca.2020.102289, PubMed 33027744
  52. Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, Johannsson OT, Ejlertsen B, Sønderstrup IMH, Hovig E, Lænkholm AV, Hansen TVO, Olafsdottir GH, Rossing M, Jonasson JG, Sigurdsson S, Loman N, Nilsson MP, Narod SA, Tryggvadottir L (2020)
    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
    Br J Cancer, 123 (11), 1608-1615
    DOI 10.1038/s41416-020-01056-4, PubMed 32939053
  53. Riis M (2020)
    Future perspectives of surgical treatment of breast cancer
    Ann Med Surg (Lond), 59, 93-95
    DOI 10.1016/j.amsu.2020.09.021, PubMed 33005399
  54. Li X, Salzano G, Qiu J, Menard M, Berg K, Theodossiou T, Ladavière C, Gref R (2020)
    Drug-Loaded Lipid-Coated Hybrid Organic-Inorganic "Stealth" Nanoparticles for Cancer Therapy
    Front Bioeng Biotechnol, 8, 1027
    DOI 10.3389/fbioe.2020.01027, PubMed 33042960
  55. Tsjokajev A, Røberg-Larsen H, Wilson SR, Dyve Lingelem AB, Skotland T, Sandvig K, Lundanes E (2020)
    Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase
    J Chromatogr B Analyt Technol Biomed Life Sci, 1160, 122384
    DOI 10.1016/j.jchromb.2020.122384, PubMed 32971370
  56. Woldemariam NT, Agafonov O, Sindre H, Høyheim B, Houston RD, Robledo D, Bron JE, Andreassen R (2020)
    miRNAs Predicted to Regulate Host Anti-viral Gene Pathways in IPNV-Challenged Atlantic Salmon Fry Are Affected by Viral Load, and Associated With the Major IPN Resistance QTL Genotypes in Late Infection
    Front Immunol, 11, 2113
    DOI 10.3389/fimmu.2020.02113, PubMed 33013890
  57. Ji X, Lin L, Shen S, Dong X, Chen C, Li Y, Zhu Y, Huang H, Chen J, Chen X, Wei L, He J, Duan W, Su L, Jiang Y, Fan J, Guan J, You D, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M et al. (2020)
    Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients
    Mol Oncol, 14 (11), 2759-2774
    DOI 10.1002/1878-0261.12785, PubMed 33448640
  58. Mato AR, Roeker LE, Lamanna N, Allan JN, Leslie L, Pagel JM, Patel K, Osterborg A, Wojenski D, Kamdar M, Huntington SF, Davids MS, Brown JR, Antic D, Jacobs R, Ahn IE, Pu J, Isaac KM, Barr PM, Ujjani CS, Geyer MB, Berman E, Zelenetz AD, Malakhov N, Furman RR et al. (2020)
    Outcomes of COVID-19 in patients with CLL: a multicenter international experience
    Blood, 136 (10), 1134-1143
    DOI 10.1182/blood.2020006965, PubMed 32688395
  59. Hoff AM, Kraggerud SM, Alagaratnam S, Berg KCG, Johannessen B, Høland M, Nilsen G, Lingjærde OC, Andrews PW, Lothe RA, Skotheim RI (2020)
    Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas
    Endocr Relat Cancer, 27 (9), 457-468
    DOI 10.1530/ERC-20-0064, PubMed 32580154
  60. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
    Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (9), 1569
    DOI 10.1038/s41436-020-0892-4, PubMed 32690931
  61. Arstad C, Taskén K, Refinetti P, Axcrona U, Giercksky KE, Ekstrøm PO (2020)
    Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
    Prostate Cancer, 2020, 7673684
    DOI 10.1155/2020/7673684, PubMed 32908706
  62. Radzikowska U, Ding M, Tan G, Zhakparov D, Peng Y, Wawrzyniak P, Wang M, Li S, Morita H, Altunbulakli C, Reiger M, Neumann AU, Lunjani N, Traidl-Hoffmann C, Nadeau KC, O'Mahony L, Akdis C, Sokolowska M (2020)
    Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors
    Allergy, 75 (11), 2829-2845
    DOI 10.1111/all.14429, PubMed 32496587
  63. Maucourant C, Filipovic I, Ponzetta A, Aleman S, Cornillet M, Hertwig L, Strunz B, Lentini A, Reinius B, Brownlie D, Cuapio A, Ask EH, Hull RM, Haroun-Izquierdo A, Schaffer M, Klingström J, Folkesson E, Buggert M, Sandberg JK, Eriksson LI, Rooyackers O, Ljunggren HG, Malmberg KJ, Michaëlsson J, Marquardt N et al. (2020)
    Natural killer cell immunotypes related to COVID-19 disease severity
    Sci Immunol, 5 (50)
    DOI 10.1126/sciimmunol.abd6832, PubMed 32826343
  64. Radulovic M, Stenmark H (2020)
    LRRK2 to the rescue of damaged endomembranes
    EMBO J, 39 (18), e106162
    DOI 10.15252/embj.2020106162, PubMed 32803793
  65. Chen B, Dragomir MP, Fabris L, Bayraktar R, Knutsen E, Liu X, Tang C, Li Y, Shimura T, Ivkovic TC, De Los Santos MC, Anfossi S, Shimizu M, Shah MY, Ling H, Shen P, Multani AS, Pardini B, Burks JK, Katayama H, Reineke LC, Huo L, Syed M, Song S, Ferracin M et al. (2020)
    The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling
    Gastroenterology, 159 (6), 2146-2162.e33
    DOI 10.1053/j.gastro.2020.08.018, PubMed 32805281
  66. Smeby J, Kryeziu K, Berg KCG, Eilertsen IA, Eide PW, Johannessen B, Guren MG, Nesbakken A, Bruun J, Lothe RA, Sveen A (2020)
    Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
    EBioMedicine, 59, 102923
    DOI 10.1016/j.ebiom.2020.102923, PubMed 32799124
  67. Berstad MEB, Cheung LH, Weyergang A (2020)
    Production of Recombinant Gelonin Using an Automated Liquid Chromatography System
    Toxins (Basel), 12 (8)
    DOI 10.3390/toxins12080519, PubMed 32823678
  68. Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
    Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
    J Mater Chem B, 8 (31), 6710-6738
    DOI 10.1039/d0tb00861c, PubMed 32627783
  69. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2020)
    Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 117-118
    DOI 10.1007/s10689-020-00200-6, PubMed 32770425
  70. Napoli E, Stenberg VY, Juzeniene A, Hjellum GE, Bruland ØS, Larsen RH (2020)
    Calibration of sodium iodide detectors and reentrant ionization chambers for 212Pb activity in different geometries by HPGe activity determined samples
    Appl Radiat Isot, 166, 109362
    DOI 10.1016/j.apradiso.2020.109362, PubMed 32979756
  71. Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
    Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
    J Cell Biol, 219 (8)
    DOI 10.1083/jcb.202003063, PubMed 32479595
  72. Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke SW, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P et al. (2020)
    The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
    Int J Cancer, 148 (4), 800-811
    DOI 10.1002/ijc.33224, PubMed 32683684
  73. Oberst S, van Harten W, Sæter G, de Paoli P, Nagy P, Burrion JB, Lovey J, Philip T (2020)
    100 European core quality standards for cancer care and research centres
    Lancet Oncol, 21 (8), 1009-1011
    DOI 10.1016/S1470-2045(20)30318-1, PubMed 32758458
  74. Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
    Nat Cell Biol, 22 (8), 973-985
    DOI 10.1038/s41556-020-0549-1, PubMed 32753672
  75. Mastrangelopoulou M, Grigalavicius M, Raabe TH, Skarpen E, Juzenas P, Peng Q, Berg K, Theodossiou TA (2020)
    Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
    Cancer Rep (Hoboken), e1278 (in press)
    DOI 10.1002/cnr2.1278, PubMed 32737955
  76. Dominguez-Valentin M, Sampson JR, Møller P, Seppälä TT, PLSD Collaborators (2020)
    Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum
    Int J Cancer, 148 (2), 512-513
    DOI 10.1002/ijc.33214, PubMed 32783184
  77. Jena KK, Mehto S, Nath P, Chauhan NR, Sahu R, Dhar K, Das SK, Kolapalli SP, Murmu KC, Jain A, Krishna S, Sahoo BS, Chattopadhyay S, Rusten TE, Prasad P, Chauhan S, Chauhan S (2020)
    Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response
    EMBO Rep, 21 (9), e50051
    DOI 10.15252/embr.202050051, PubMed 32715615
  78. Sonnet F, Namork E, Stylianou E, Gaare-Olstad I, Huse K, Andorf S, Mjaaland S, Dirven H, Nygaard U (2020)
    Reduced polyfunctional T cells and increased cellular activation markers in adult allergy patients reporting adverse reactions to food
    BMC Immunol, 21 (1), 43
    DOI 10.1186/s12865-020-00373-w, PubMed 32698761
  79. Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
    STEEP mediates STING ER exit and activation of signaling
    Nat Immunol, 21 (8), 868-879
    DOI 10.1038/s41590-020-0730-5, PubMed 32690950
  80. Cieslar-Pobuda A, Ahrens TD, Caglayan S, Behringer S, Hannibal L, Staerk J (2020)
    DNMT3B deficiency alters mitochondrial biogenesis and α-ketoglutarate levels in human embryonic stem cells
    Stem Cells, 38 (11), 1409-1422
    DOI 10.1002/stem.3256, PubMed 32652733
  81. Gaustad JV, Hauge A, Wegner CS, Simonsen TG, Lund KV, Hansem LMK, Rofstad EK (2020)
    DCE-MRI of Tumor Hypoxia and Hypoxia-Associated Aggressiveness
    Cancers (Basel), 12 (7)
    DOI 10.3390/cancers12071979, PubMed 32698525
  82. Dominguez-Valentin M, Seppälä TT, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D et al. (2020)
    Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
    J Clin Med, 9 (7)
    DOI 10.3390/jcm9072290, PubMed 32708519
  83. Malani D, Yadav B, Kumar A, Potdar S, Kontro M, Kankainen M, Javarappa KK, Porkka K, Wolf M, Aittokallio T, Wennerberg K, Heckman CA, Murumägi A, Kallioniemi O (2020)
    KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia
    Leukemia, 34 (10), 2780-2784
    DOI 10.1038/s41375-020-0978-7, PubMed 32678289
  84. Vedeld HM, Folseraas T, Lind GE (2020)
    Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis - The promise of DNA methylation and molecular biomarkers
    JHEP Rep, 2 (5), 100143
    DOI 10.1016/j.jhepr.2020.100143, PubMed 32939446
  85. Munthe E, Raiborg C, Stenmark H, Wenzel EM (2020)
    Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
    J Cell Sci, 133 (13)
    DOI 10.1242/jcs.244467, PubMed 32546530
  86. Kyte JA, Andresen NK, Russnes HG, Fretland SØ, Falk RS, Lingjærde OC, Naume B (2020)
    ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patients with metastatic hormone receptor positive breast cancer
    J Transl Med, 18 (1), 269
    DOI 10.1186/s12967-020-02421-w, PubMed 32620163
  87. Ianevski A, Giri AK, Aittokallio T (2020)
    SynergyFinder 2.0: visual analytics of multi-drug combination synergies
    Nucleic Acids Res, 48 (W1), W488-W493
    DOI 10.1093/nar/gkaa216, PubMed 32246720
  88. Georgiesh T, Boye K, Bjerkehagen B (2020)
    A novel risk score to predict early and late recurrence in solitary fibrous tumour
    Histopathology, 77 (1), 123-132
    DOI 10.1111/his.14078, PubMed 31991494
  89. Itkonen HM, Poulose N, Steele RE, Martin SES, Levine ZG, Duveau DY, Carelli R, Singh R, Urbanucci A, Loda M, Thomas CJ, Mills IG, Walker S (2020)
    Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9
    Mol Cancer Res, 18 (10), 1512-1521
    DOI 10.1158/1541-7786.MCR-20-0339, PubMed 32611550
  90. Terkelsen T, Russo F, Gromov P, Haakensen VD, Brunak S, Gromova I, Krogh A, Papaleo E (2020)
    Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration
    Breast Cancer Res, 22 (1), 73
    DOI 10.1186/s13058-020-01295-6, PubMed 32605588
  91. Hillestad T, Hompland T, Fjeldbo CS, Skingen VE, Salberg UB, Aarnes EK, Nilsen A, Lund KV, Evensen TS, Kristensen GB, Stokke T, Lyng H (2020)
    MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer
    Cancer Res, 80 (18), 3993-4003
    DOI 10.1158/0008-5472.CAN-20-0950, PubMed 32606004
  92. Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
    Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
    Nat Cell Biol, 22 (7), 856-867
    DOI 10.1038/s41556-020-0537-5, PubMed 32601372
  93. Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, Øy GF, Bøe SL, Urbanucci A, Hovig E (2020)
    Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
    Cancers (Basel), 12 (7)
    DOI 10.3390/cancers12071719, PubMed 32605315
  94. Russnes HG (2020)
    Clinical trials in the era of precision cancer medicine - for the few or for the many?
    Acta Oncol, 59 (7), 731-732
    DOI 10.1080/0284186X.2020.1777582, PubMed 32579040
  95. Riis M (2020)
    Modern surgical treatment of breast cancer
    Ann Med Surg (Lond), 56, 95-107
    DOI 10.1016/j.amsu.2020.06.016, PubMed 32637082
  96. Kyte JA, Røssevold A, Falk RS, Naume B (2020)
    ALICE: a randomized placebo-controlled phase II study evaluating atezolizumab combined with immunogenic chemotherapy in patients with metastatic triple-negative breast cancer
    J Transl Med, 18 (1), 252
    DOI 10.1186/s12967-020-02424-7, PubMed 32576225
  97. Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Sætre F, Hagen KT, Yaqub S, Øyen O, Horneland R, Aandahl EM, Aabakken L, Bækkevold ES, Jahnsen FL (2020)
    CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile
    Mucosal Immunol, 14 (2), 402-410
    DOI 10.1038/s41385-020-0315-5, PubMed 32572129
  98. Fjeldbo CS, Hompland T, Hillestad T, Aarnes EK, Günther CC, Kristensen GB, Malinen E, Lyng H (2020)
    Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity
    EBioMedicine, 57, 102841
    DOI 10.1016/j.ebiom.2020.102841, PubMed 32580139
  99. von der Lippe Gythfeldt H, Lien T, Tekpli X, Silwal-Pandit L, Borgen E, Garred Ø, Skjerven H, Schlichting E, Lundgren S, Wist E, Naume B, Kristensen V, Børresen-Dale AL, Lingjaerde OC, Engebraaten O (2020)
    Immune phenotype of tumor microenvironment predicts response to bevacizumab in neoadjuvant treatment of ER-positive breast cancer
    Int J Cancer, 147 (9), 2515-2525
    DOI 10.1002/ijc.33108, PubMed 32488909
  100. Pace M, Falappa M, Freschi A, Balzani E, Berteotti C, Lo Martire V, Kaveh F, Hovig E, Zoccoli G, Amici R, Cerri M, Urbanucci A, Tucci V (2020)
    Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
    JCI Insight, 5 (12)
    DOI 10.1172/jci.insight.137495, PubMed 32365348
  101. Haakensen VD, Khadse A, Sandhu V, Halvorsen AR, Solberg SK, Jørgensen LH, Brustugun OT, Kure EH, Helland Å (2020)
    Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy
    Int J Cancer, 147 (10), 2957-2966
    DOI 10.1002/ijc.33121, PubMed 32468587
  102. Bergholtz H, Lien TG, Swanson DM, Frigessi A, Oslo Breast Cancer Research Consortium (OSBREAC), Daidone MG, Tost J, Wärnberg F, Sørlie T (2020)
    Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions
    NPJ Breast Cancer, 6, 26
    DOI 10.1038/s41523-020-0167-x, PubMed 32577501
  103. Kohvakka A, Sattari M, Shcherban A, Annala M, Urbanucci A, Kesseli J, Tammela TLJ, Kivinummi K, Latonen L, Nykter M, Visakorpi T (2020)
    AR and ERG drive the expression of prostate cancer specific long noncoding RNAs
    Oncogene, 39 (30), 5241-5251
    DOI 10.1038/s41388-020-1365-6, PubMed 32555329
  104. Weber S, Spiegl B, Perakis SO, Ulz CM, Abuja PM, Kashofer K, Leest PV, Azpurua MA, Tamminga M, Brudzewsky D, Rothwell DG, Mohan S, Sartori A, Lampignano R, Konigshofer Y, Sprenger-Haussels M, Wikman H, Bergheim IR, Kloten V, Schuuring E, Speicher MR, Heitzer E (2020)
    Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling
    Cancers (Basel), 12 (6)
    DOI 10.3390/cancers12061588, PubMed 32560092
  105. Álvarez K, Orellana P, De la Fuente M, Canales T, Pinto E, Heine C, Solar B, Hurtado C, Møller P, Kronberg U, Zarate AJ, Dominguez-Valentin M, López-Köstner F (2020)
    Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
    J Clin Med, 9 (6)
    DOI 10.3390/jcm9061861, PubMed 32549215
  106. Napoli E, Cessna JT, Pibida L, Fitzgerald R, Hjellum GE, Bergeron DE (2020)
    Radionuclide calibrator responses for 224Ra in solution and adsorbed on calcium carbonate microparticles
    Appl Radiat Isot, 164, 109265
    DOI 10.1016/j.apradiso.2020.109265, PubMed 32763787
  107. Zhu H, Blum RH, Bernareggi D, Ask EH, Wu Z, Hoel HJ, Meng Z, Wu C, Guan KL, Malmberg KJ, Kaufman DS (2020)
    Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
    Cell Stem Cell, 27 (2), 224-237.e6
    DOI 10.1016/j.stem.2020.05.008, PubMed 32531207
  108. Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S (2020)
    Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds
    Cancers (Basel), 12 (6)
    DOI 10.3390/cancers12061516, PubMed 32531927
  109. Stankovic B, Aamodt H, Bjørhovde HAK, Müller E, Hammarström C, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2020)
    The immune microenvironment in typical carcinoid lung tumour, a brief report of four cases
    Scand J Immunol, 92 (2), e12893
    DOI 10.1111/sji.12893, PubMed 32433774
  110. Chen C, Wei Y, Wei L, Chen J, Chen X, Dong X, He J, Lin L, Zhu Y, Huang H, You D, Lai L, Shen S, Duan W, Su L, Shafer A, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Wang R, Staaf J, Helland Å, Esteller M, Zhang R et al. (2020)
    Epigenome-wide gene-age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients
    Aging (Albany NY), 12 (11), 10642-10662
    DOI 10.18632/aging.103284, PubMed 32511103
  111. Seppälä TT, Dominguez-Valentin M, Sampson JR, Møller P (2020)
    Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)
    Fam Cancer, 20 (1), 35-39
    DOI 10.1007/s10689-020-00193-2, PubMed 32507935
  112. Flatmark K, Mohamed F (2020)
    ASO Author Reflections: Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
    Ann Surg Oncol, 27 (Suppl 3), 771-772
    DOI 10.1245/s10434-020-08691-4, PubMed 32495284
  113. Patrick-Brown TDJH, Carr NJ, Swanson DM, Larsen S, Mohamed F, Flatmark K (2020)
    Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
    Ann Surg Oncol, 28 (1), 252-257
    DOI 10.1245/s10434-020-08655-8, PubMed 32488520
  114. Dillard P, Lie M, Baken E, Lobert VH, Benard E, Köksal H, Inderberg EM, Wälchli S (2020)
    Colorectal cysts as a validating tool for CAR therapy
    BMC Biotechnol, 20 (1), 30
    DOI 10.1186/s12896-020-00623-0, PubMed 32487146
  115. Skotland T, Kavaliauskiene S, Sandvig K (2020)
    The role of lipid species in membranes and cancer-related changes
    Cancer Metastasis Rev, 39 (2), 343-360
    DOI 10.1007/s10555-020-09872-z, PubMed 32314087
  116. Bergholtz H, Kumar S, Wärnberg F, Lüders T, Kristensen V, Sørlie T (2020)
    Comparable cancer-relevant mutation profiles in synchronous ductal carcinoma in situ and invasive breast cancer
    Cancer Rep (Hoboken), 3 (3), e1248
    DOI 10.1002/cnr2.1248, PubMed 32671987
  117. Jacomin AC, Petridi S, Di Monaco M, Bhujabal Z, Jain A, Mulakkal NC, Palara A, Powell EL, Chung B, Zampronio C, Jones A, Cameron A, Johansen T, Nezis IP (2020)
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
    Cell Rep, 31 (8), 107695
    DOI 10.1016/j.celrep.2020.107695, PubMed 32460019
  118. Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
    Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
    Cell Mol Life Sci, 78 (3), 985-1009
    DOI 10.1007/s00018-020-03551-6, PubMed 32447426
  119. Fleten KG, Lund-Andersen C, Waagene S, Abrahamsen TW, Mørch Y, Boye K, Torgunrud A, Flatmark K (2020)
    Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models
    Transl Oncol, 13 (8), 100793
    DOI 10.1016/j.tranon.2020.100793, PubMed 32447231
  120. Hauge A, Rofstad EK (2020)
    Antifibrotic therapy to normalize the tumor microenvironment
    J Transl Med, 18 (1), 207
    DOI 10.1186/s12967-020-02376-y, PubMed 32434573
  121. Zhang H, Ahearn TU, Lecarpentier J, Barnes D, Beesley J, Qi G, Jiang X, O'Mara TA, Zhao N, Bolla MK, Dunning AM, Dennis J, Wang Q, Ful ZA, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Arun BK, Auer PL, Azzollini J, Barrowdale D, Becher H, Beckmann MW et al. (2020)
    Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
    Nat Genet, 52 (6), 572-581
    DOI 10.1038/s41588-020-0609-2, PubMed 32424353
  122. Ferrante L, Opdal SH, Nygaard V (2020)
    No association to sudden infant death syndrome detected by targeted amplicon sequencing of 24 genes
    Acta Paediatr, 109 (12), 2636-2640
    DOI 10.1111/apa.15295, PubMed 32271962
  123. Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
    Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
    Blood Adv, 4 (9), 1859-1866
    DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
  124. Pfefferle A, Jacobs B, Haroun-Izquierdo A, Kveberg L, Sohlberg E, Malmberg KJ (2020)
    Deciphering Natural Killer Cell Homeostasis
    Front Immunol, 11, 812
    DOI 10.3389/fimmu.2020.00812, PubMed 32477340
  125. Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
    Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
    iScience, 23 (6), 101154
    DOI 10.1016/j.isci.2020.101154, PubMed 32450518
  126. Helgeland H, Gabrielsen I, Akselsen H, Sundaram AYM, Flåm ST, Lie BA (2020)
    Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells
    BMC Genomics, 21 (1), 350
    DOI 10.1186/s12864-020-6755-1, PubMed 32393182
  127. Frafjord A, Skarshaug R, Hammarström C, Stankovic B, Dorg LT, Aamodt H, Woldbaek PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2020)
    Antibody combinations for optimized staining of macrophages in human lung tumours
    Scand J Immunol, 92 (1), e12889
    DOI 10.1111/sji.12889, PubMed 32299134
  128. Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
    Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
    Cells, 9 (5)
    DOI 10.3390/cells9051171, PubMed 32397238
  129. Egeland NG, Jonsdottir K, Aure MR, Sahlberg K, Kristensen VN, Cronin-Fenton D, Skaland I, Gudlaugsson E, Baak JPA, Janssen EAM (2020)
    MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers
    BMC Cancer, 20 (1), 377
    DOI 10.1186/s12885-020-06857-7, PubMed 32370743
  130. Peng W, de Bruijn HS, Ten Hagen TLM, van Dam GM, Roodenburg JLN, Berg K, Witjes MJH, Robinson DJ (2020)
    Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model
    Photochem Photobiol, 96 (3), 708-717
    DOI 10.1111/php.13267, PubMed 32222965
  131. Kotsopoulos J, Karlan B, Gronwald J, Hall E, Moller P, Tung N, Zakalik D, Foulkes WD, Rosen B, Neuhausen SL, Sun P, Lubinksi J, Narod SA (2020)
    Long-term outcomes following a diagnosis of ovarian cancer at the time of preventive oophorectomy among BRCA1 and BRCA2 mutation carriers
    Int J Gynecol Cancer, 30 (6), 825-830
    DOI 10.1136/ijgc-2019-001141, PubMed 32354794
  132. Clement D, Goodridge JP, Grimm C, Patel S, Malmberg KJ (2020)
    TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells
    Front Immunol, 11, 753
    DOI 10.3389/fimmu.2020.00753, PubMed 32411146
  133. Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
    Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
    Commun Biol, 3 (1), 196
    DOI 10.1038/s42003-020-0916-2, PubMed 32332858
  134. Grigalavicius M, Mastrangelopoulou M, Arous D, Juzeniene A, Ménard M, Skarpen E, Berg K, Theodossiou TA (2020)
    Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures
    Photochem Photobiol, 96 (3), 699-707
    DOI 10.1111/php.13257, PubMed 32125700
  135. Berger I, Berland S, Rodriguez JR, Aamodt H, Sitek JC, Jørgensen K, Johansen TEB (2020)
    Birt-Hogg-Dubé syndrome
    Tidsskr Nor Laegeforen, 140 (6)
    DOI 10.4045/tidsskr.18.0848, PubMed 32321218
  136. Nilsen J, Trabjerg E, Grevys A, Azevedo C, Brennan SO, Stensland M, Wilson J, Sand KMK, Bern M, Dalhus B, Roopenian DC, Sandlie I, Rand KD, Andersen JT (2020)
    An intact C-terminal end of albumin is required for its long half-life in humans
    Commun Biol, 3 (1), 181
    DOI 10.1038/s42003-020-0903-7, PubMed 32313072
  137. Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Røsok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjørnbeth BA, Sveen A, Lothe RA (2020)
    Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
    Clin Cancer Res, 26 (15), 4107-4119
    DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813
  138. Ferrante L, Opdal SH, Nygård S, Vege Å, Rognum TO (2020)
    Gene expression profile in cases of infectious death in infancy
    Pediatr Res, 89 (3), 483-487
    DOI 10.1038/s41390-020-0896-4, PubMed 32299088
  139. Lund KV, Simonsen TG, Kristensen GB, Rofstad EK (2020)
    DCE-MRI of locally-advanced carcinoma of the uterine cervix: Tofts analysis versus non-model-based analyses
    Radiat Oncol, 15 (1), 79
    DOI 10.1186/s13014-020-01526-2, PubMed 32293487
  140. Fougner C, Bergholtz H, Norum JH, Sørlie T (2020)
    Re-definition of claudin-low as a breast cancer phenotype
    Nat Commun, 11 (1), 1787
    DOI 10.1038/s41467-020-15574-5, PubMed 32286297
  141. Buratta S, Tancini B, Sagini K, Delo F, Chiaradia E, Urbanelli L, Emiliani C (2020)
    Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular
    Int J Mol Sci, 21 (7)
    DOI 10.3390/ijms21072576, PubMed 32276321
  142. Jeanmougin M, Håvik AB, Cekaite L, Brandal P, Sveen A, Meling TR, Ågesen TH, Scheie D, Heim S, Lothe RA, Lind GE (2020)
    Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
    Mol Oncol, 14 (5), 1016-1027
    DOI 10.1002/1878-0261.12668, PubMed 32171051
  143. Malenge MM, Patzke S, Ree AH, Stokke T, Ceuppens P, Middleton B, Dahle J, Repetto-Llamazares AHV (2020)
    177Lu-Lilotomab Satetraxetan Has the Potential to Counteract Resistance to Rituximab in Non-Hodgkin Lymphoma
    J Nucl Med, 61 (10), 1468-1475
    DOI 10.2967/jnumed.119.237230, PubMed 32245896
  144. Bazarbachi A, Bug G, Baron F, Brissot E, Ciceri F, Dalle IA, Döhner H, Esteve J, Floisand Y, Giebel S, Gilleece M, Gorin NC, Jabbour E, Aljurf M, Kantarjian H, Kharfan-Dabaja M, Labopin M, Lanza F, Malard F, Peric Z, Prebet T, Ravandi F, Ruggeri A, Sanz J, Schmid C et al. (2020)
    Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3-internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
    Haematologica, 105 (6), 1507-1516
    DOI 10.3324/haematol.2019.243410, PubMed 32241850
  145. Pladsen AV, Nilsen G, Rueda OM, Aure MR, Borgan Ø, Liestøl K, Vitelli V, Frigessi A, Langerød A, Mathelier A, OSBREAC, Engebråten O, Kristensen V, Wedge DC, Van Loo P, Caldas C, Børresen-Dale AL, Russnes HG, Lingjærde OC (2020)
    DNA copy number motifs are strong and independent predictors of survival in breast cancer
    Commun Biol, 3 (1), 153
    DOI 10.1038/s42003-020-0884-6, PubMed 32242091
  146. De Las Heras J, Diez I, Jimenez-Marin A, Cabrera A, Ramos-Usuga D, Diaz-Fernandez MV, Torices L, Nunes-Xavier CE, Pulido R, Arango-Lasprilla JC, Cortes JM (2020)
    Brain Circuit Alterations and Cognitive Disability in Late-Onset Cobalamin D Disorder
    J Clin Med, 9 (4)
    DOI 10.3390/jcm9040990, PubMed 32252256
  147. Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
    Analytical techniques for multiplex analysis of protein biomarkers
    Expert Rev Proteomics, 17 (4), 257-273
    DOI 10.1080/14789450.2020.1763174, PubMed 32427033
  148. Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
    Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
    J Biomed Nanotechnol, 16 (4), 419-431
    DOI 10.1166/jbn.2020.2911, PubMed 32970975
  149. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  150. Brustugun OT, Sorhaug S, Gronberg BH, Aanerud M, Al-Zubayidy MMZ, Fjellbirkeland L, Helland A, Berg J, Andreassen B, Paulsen EE, Haram PM, Ashraf H, Wahl SGF (2020)
    Lung cancer: Improved prognosis presents capacity challenges
    Tidsskr. Nor. Laegeforen., 140 (5), 432-434
  151. Lopes N, Bergsland C, Bruun J, Bjørnslett M, Vieira AF, Mesquita P, Pinto R, Gomes R, Cavadas B, Bennett E, Pereira L, Lothe RA, Almeida R, David L (2020)
    A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
    Gastric Cancer, 23 (5), 811-823
    DOI 10.1007/s10120-020-01064-6, PubMed 32215766
  152. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
    Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
    Acta Oncol, 59 (7), 733-740
    DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
  153. Humbert M, Morán M, de la Cruz-Ojeda P, Muntané J, Wiedmer T, Apostolova N, McKenna SL, Velasco G, Balduini W, Eckhart L, Janji B, Sampaio-Marques B, Ludovico P, Žerovnik E, Langer R, Perren A, Engedal N, Tschan MP (2020)
    Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot
    Biology (Basel), 9 (3)
    DOI 10.3390/biology9030059, PubMed 32245178
  154. Majzner RG, Rietberg SP, Sotillo E, Dong R, Vachharajani VT, Labanieh L, Myklebust JH, Kadapakkam M, Weber EW, Tousley AM, Richards RM, Heitzeneder S, Nguyen SM, Wiebking V, Theruvath J, Lynn RC, Xu P, Dunn AR, Vale RD, Mackall CL (2020)
    Tuning the Antigen Density Requirement for CAR T-cell Activity
    Cancer Discov, 10 (5), 702-723
    DOI 10.1158/2159-8290.CD-19-0945, PubMed 32193224
  155. Steinhaeuser SS, Morera E, Budkova Z, Schepsky A, Wang Q, Rolfsson O, Riedel A, Krueger A, Hilmarsdottir B, Maelandsmo GM, Valdimarsdottir B, Sigurdardottir AK, Agnarsson BA, Jonasson JG, Ingthorsson S, Traustadottir GA, Oskarsson T, Gudjonsson T (2020)
    ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion
    Lab Invest, 100 (7), 928-944
    DOI 10.1038/s41374-020-0415-6, PubMed 32203150
  156. Jerjes W, Hamdoon Z, Berg K, Høgset A, Hopper C (2020)
    Apparent Complete Response of a Treatment Refractory and Recurrent Squamous Cell Carcinoma Lesion to Photochemical Internalization: A Clinical Case Study
    Photochem Photobiol, 96 (3), 680-683
    DOI 10.1111/php.13210, PubMed 31901218
  157. Hernández-Sandoval JA, Gutiérrez-Angulo M, Magaña-Torres MT, Alvizo-Rodríguez CR, Ramírez-Plascencia HHF, Flores-López BA, Valenzuela-Pérez JA, Peregrina-Sandoval J, Moreno-Ortiz JM, Domínguez-Valentín M, Ayala-Madrigal ML (2020)
    Prevalence of the BRAF p.v600e variant in patients with colorectal cancer from Mexico and its estimated frequency in Latin American and Caribbean populations
    J Investig Med, 68 (5), 985-991
    DOI 10.1136/jim-2020-001301, PubMed 32184228
  158. Møller P (2020)
    The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care
    Hered Cancer Clin Pract, 18, 6
    DOI 10.1186/s13053-020-0138-0, PubMed 32190163
  159. Eide IJZ, Helland Å, Ekman S, Mellemgaard A, Hansen KH, Cicenas S, Koivunen J, Grønberg BH, Brustugun OT (2020)
    Osimertinib in T790M-positive and -negative patients with EGFR-mutated advanced non-small cell lung cancer (the TREM-study)
    Lung Cancer, 143, 27-35
    DOI 10.1016/j.lungcan.2020.03.009, PubMed 32200138
  160. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
  161. Serguienko A, Braadland P, Meza-Zepeda LA, Bjerkehagen B, Myklebost O (2020)
    Accurate 3-gene-signature for early diagnosis of liposarcoma progression
    Clin Sarcoma Res, 10, 4
    DOI 10.1186/s13569-020-0126-1, PubMed 32158531
  162. Remberger M, Grønvold B, Ali M, Mattsson J, Egeland T, Lundin KU, Myhre A, Abrahamsen I, Heldal D, Dybedal I, Tjønnfjord GE, Gedde-Dahl T, Fløisand Y (2020)
    The CD34+ Cell Dose Matters in Hematopoietic Stem Cell Transplantation with Peripheral Blood Stem Cells from Sibling Donors
    Clin Hematol Int, 2 (2), 74-81
    DOI 10.2991/chi.d.200221.001, PubMed 34595446
  163. Akimov Y, Bulanova D, Timonen S, Wennerberg K, Aittokallio T (2020)
    Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics
    Mol Syst Biol, 16 (3), e9195
    DOI 10.15252/msb.20199195, PubMed 32187448
  164. Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-Full Z, Aittomäki K, Andrulis IL, Anton-Culver H, Antoniou AC, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Auer PL, Azzollini J, Balmaña J, Barkardottir RB, Barnes DR, Barrowdale D, Beckmann MW, Behrens S, Benitez J, Bermisheva M et al. (2020)
    Transcriptome-wide association study of breast cancer risk by estrogen-receptor status
    Genet Epidemiol, 44 (5), 442-468
    DOI 10.1002/gepi.22288, PubMed 32115800
  165. Zhang R, Chen C, Dong X, Shen S, Lai L, He J, You D, Lin L, Zhu Y, Huang H, Chen J, Wei L, Chen X, Li Y, Guo Y, Duan W, Liu L, Su L, Shafer A, Fleischer T, Moksnes Bjaanæs M, Karlsson A, Planck M, Wang R, Staaf J et al. (2020)
    Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects
    Chest, 158 (2), 808-819
    DOI 10.1016/j.chest.2020.01.048, PubMed 32113923
  166. Wong JJW, Selbo PK (2020)
    High aldehyde dehydrogenase activity does not protect colon cancer cells against TPCS2a-sensitized photokilling
    Photochem Photobiol Sci, 19 (3), 308-312
    DOI 10.1039/c9pp00453j, PubMed 32108197
  167. Dagenborg VJ, Marshall SE, Yaqub S, Grzyb K, Boye K, Lund-Iversen M, Høye E, Berstad AE, Fretland ÅA, Edwin B, Ree AH, Flatmark K (2020)
    Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases
    Cancer Biol Ther, 21 (5), 432-440
    DOI 10.1080/15384047.2020.1721252, PubMed 32098573
  168. Saeednejad Zanjani L, Madjd Z, Axcrona U, Abolhasani M, Rasti A, Asgari M, Fodstad Ø, Andersson Y (2020)
    Cytoplasmic expression of B7-H3 and membranous EpCAM expression are associated with higher grade and survival outcomes in patients with clear cell renal cell carcinoma
    Ann Diagn Pathol, 46, 151483
    DOI 10.1016/j.anndiagpath.2020.151483, PubMed 32143173
  169. Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Furu K, Juzeniene A, Roscher I, Larsen IK, Green AC, Veierød MB, Robsahm TE (2020)
    Use of Antidepressants and Risk of Cutaneous Melanoma: A Prospective Registry-Based Case-Control Study
    Clin Epidemiol, 12, 193-202
    DOI 10.2147/CLEP.S241249, PubMed 32110111
  170. Abravan A, Eide HA, Helland Å, Malinen E (2020)
    Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy
    Clin Transl Radiat Oncol, 22, 15-21
    DOI 10.1016/j.ctro.2020.02.005, PubMed 32181373
  171. Zhu Q, Tekpli X, Troyanskaya OG, Kristensen VN (2020)
    Subtype-specific transcriptional regulators in breast tumors subjected to genetic and epigenetic alterations
    Bioinformatics, 36 (4), 994-999
    DOI 10.1093/bioinformatics/btz709, PubMed 31529022
  172. Jerjes W, Theodossiou TA, Hirschberg H, Høgset A, Weyergang A, Selbo PK, Hamdoon Z, Hopper C, Berg K (2020)
    Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research
    J Clin Med, 9 (2)
    DOI 10.3390/jcm9020528, PubMed 32075165
  173. Grønvold B, Ali MM, Remberger M, Mattsson J, Egeland T, Lundin KU, Myhre AE, Abrahamsen IW, Heldal D, Dybedal I, Tjønnfjord GE, Fløisand Y, Gedde-Dahl T (2020)
    HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation
    Bone Marrow Transplant, 55 (8), 1658-1661
    DOI 10.1038/s41409-020-0827-3, PubMed 32054997
  174. Laiouar S, Berns N, Brech A, Riechmann V (2020)
    RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism
    Curr Biol, 30 (7), 1177-1188.e5
    DOI 10.1016/j.cub.2020.01.048, PubMed 32059769
  175. Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
    Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020417, PubMed 32053965
  176. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2020)
    Correction: Møller, P.; et al. Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift. Cancers 2019, 11, 132
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020410, PubMed 32050665
  177. Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
    The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
    Toxicology, 433-434, 152405
    DOI 10.1016/j.tox.2020.152405, PubMed 32044396
  178. Darvekar S, Juzenas P, Oksvold M, Kleinauskas A, Holien T, Christensen E, Stokke T, Sioud M, Peng Q (2020)
    Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020377, PubMed 32041351
  179. Jakobsen LH, Ellin F, Smeland KB, Wästerlid T, Christensen JH, Jørgensen JM, Josefsson PL, Øvlisen AK, Holte H, Blaker YN, Grauslund JH, Bjørn J, Molin D, Lagerlöf I, Smedby KE, Colvin K, Thanarajasingam G, Maurer MJ, Habermann TM, Song KW, Zhu KY, Gerrie AS, Cheah CY, El-Galaly TC (2020)
    Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy: an international study of 264 real-world patients
    Br J Haematol, 189 (4), 661-671
    DOI 10.1111/bjh.16425, PubMed 32017050
  180. Lien VT, Kristiansen MK, Pettersen S, Haugen MH, Krauss S, Olberg DE, Waaler J, Klaveness J (2020)
    Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation (vol 9, pg 37092, 2019)
    RSC Adv., 10 (9), 4927
    DOI 10.1039/d0ra90007a
  181. ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (2020)
    Pan-cancer analysis of whole genomes
    Nature, 578 (7793), 82-93
    DOI 10.1038/s41586-020-1969-6, PubMed 32025007
  182. Stenberg VY, Juzeniene A, Chen Q, Yang X, Bruland ØS, Larsen RH (2020)
    Preparation of the alpha-emitting prostate-specific membrane antigen targeted radioligand [212 Pb]Pb-NG001 for prostate cancer
    J Labelled Comp Radiopharm, 63 (3), 129-143
    DOI 10.1002/jlcr.3825, PubMed 31919866
  183. Knutsen E, Lellahi SM, Aure MR, Nord S, Fismen S, Larsen KB, Gabriel MT, Hedberg A, Bjørklund SS, Oslo Breast Cancer Research Consortium (OSBREAC), Bofin AM, Mælandsmo GM, Sørlie T, Mortensen ES, Perander M (2020)
    The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
    Sci Rep, 10 (1), 1277
    DOI 10.1038/s41598-020-57759-4, PubMed 31992741
  184. Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C (2020)
    Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
    Nat Commun, 11 (1), 440
    DOI 10.1038/s41467-020-14343-8, PubMed 31974402
  185. Goleva-Fjellet S, Bjurholt AM, Kure EH, Larsen IK, Støren Ø, Sæbø M (2020)
    Distribution of allele frequencies for genes associated with physical activity and/or physical capacity in a homogenous Norwegian cohort- a cross-sectional study
    BMC Genet, 21 (1), 8
    DOI 10.1186/s12863-020-0813-1, PubMed 31973699
  186. Chu DT, Phuong TNT, Tien NLB, Tran DK, Thanh VV, Quang TL, Truong DT, Pham VH, Ngoc VTN, Chu-Dinh T, Kushekhar K (2020)
    An Update on the Progress of Isolation, Culture, Storage, and Clinical Application of Human Bone Marrow Mesenchymal Stem/Stromal Cells
    Int J Mol Sci, 21 (3)
    DOI 10.3390/ijms21030708, PubMed 31973182
  187. Omsland M, Andresen V, Gullaksen SE, Ayuda-Durán P, Popa M, Hovland R, Brendehaug A, Enserink J, McCormack E, Gjertsen BT (2020)
    Tyrosine kinase inhibitors and interferon-α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines
    FASEB J, 34 (3), 3773-3791
    DOI 10.1096/fj.201802061RR, PubMed 31945226
  188. Escala-Garcia M, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Ashworth A, Auer PL, Auvinen P, Beckmann MW, Beesley J, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Blot W, Bogdanova NV, Bojesen SE, Bolla MK, Børresen-Dale AL, Brauch H, Brenner H, Brucker SY, Burwinkel B, Caldas C, Canzian F et al. (2020)
    A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
    Nat Commun, 11 (1), 312
    DOI 10.1038/s41467-019-14100-6, PubMed 31949161
  189. Dal NK, Kocere A, Wohlmann J, Van Herck S, Bauer TA, Resseguier J, Bagherifam S, Hyldmo H, Barz M, De Geest BG, Fenaroli F (2020)
    Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle-Cell Interactions
    Small, 16 (5), e1906719
    DOI 10.1002/smll.201906719, PubMed 31943784
  190. Rein ID, Notø HØ, Bostad M, Huse K, Stokke T (2020)
    Cell Cycle Analysis and Relevance for Single-Cell Gating in Mass Cytometry
    Cytometry A, 97 (8), 832-844
    DOI 10.1002/cyto.a.23960, PubMed 31943748
  191. Zhao S, Hoff AM, Skotheim RI (2020)
    ScaR-a tool for sensitive detection of known fusion transcripts: establishing prevalence of fusions in testicular germ cell tumors
    NAR Genom Bioinform, 2 (1), lqz025
    DOI 10.1093/nargab/lqz025, PubMed 33575572
  192. Kuttner S, Wickstrøm KK, Kalda G, Dorraji SE, Martin-Armas M, Oteiza A, Jenssen R, Fenton K, Sundset R, Axelsson J (2020)
    Machine learning derived input-function in a dynamic 18F-FDG PET study of mice
    Biomed Phys Eng Express, 6 (1), 015020
    DOI 10.1088/2057-1976/ab6496, PubMed 33438608
  193. Peng W, de Bruijn HS, Ten Hagen TLM, Berg K, Roodenburg JLN, van Dam GM, Witjes MJH, Robinson DJ (2020)
    In-Vivo Optical Monitoring of the Efficacy of Epidermal Growth Factor Receptor Targeted Photodynamic Therapy: The Effect of Fluence Rate
    Cancers (Basel), 12 (1)
    DOI 10.3390/cancers12010190, PubMed 31940973
  194. Umu SU, Langseth H, Keller A, Meese E, Helland Å, Lyle R, Rounge TB (2020)
    A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis
    Mol Oncol, 14 (2), 235-247
    DOI 10.1002/1878-0261.12620, PubMed 31851411
  195. Šošić L, Selbo PK, Kotkowska ZK, Kündig TM, Høgset A, Johansen P (2020)
    Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines
    Cancers (Basel), 12 (1)
    DOI 10.3390/cancers12010165, PubMed 31936595
  196. Flem-Karlsen K, Nyakas M, Farstad IN, McFadden E, Wernhoff P, Jacobsen KD, Flørenes VA, Mælandsmo GM (2020)
    Soluble AXL as a marker of disease progression and survival in melanoma
    PLoS One, 15 (1), e0227187
    DOI 10.1371/journal.pone.0227187, PubMed 31917795
  197. Meås HZ, Haug M, Beckwith MS, Louet C, Ryan L, Hu Z, Landskron J, Nordbø SA, Taskén K, Yin H, Damås JK, Flo TH (2020)
    Sensing of HIV-1 by TLR8 activates human T cells and reverses latency
    Nat Commun, 11 (1), 147
    DOI 10.1038/s41467-019-13837-4, PubMed 31919342
  198. Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
    Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
    Resuscitation, 149, 170-179
    DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258
  199. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D132-D141
    DOI 10.1093/nar/gkz885, PubMed 31598695
  200. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D1172
    DOI 10.1093/nar/gkz1016, PubMed 31642479
  201. Fornes O, Castro-Mondragon JA, Khan A, van der Lee R, Zhang X, Richmond PA, Modi BP, Correard S, Gheorghe M, Baranašić D, Santana-Garcia W, Tan G, Chèneby J, Ballester B, Parcy F, Sandelin A, Lenhard B, Wasserman WW, Mathelier A (2020)
    JASPAR 2020: update of the open-access database of transcription factor binding profiles
    Nucleic Acids Res, 48 (D1), D87-D92
    DOI 10.1093/nar/gkz1001, PubMed 31701148
  202. Simonsen TG, Gaustad JV, Rofstad EK (2020)
    Bevacizumab treatment of meningeal melanoma metastases
    J Transl Med, 18 (1), 13
    DOI 10.1186/s12967-020-02212-3, PubMed 31915016
  203. Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
    Biological response and cytotoxicity induced by lipid nanocapsules
    J Nanobiotechnology, 18 (1), 5
    DOI 10.1186/s12951-019-0567-y, PubMed 31907052
  204. Sæbøe-Larssen S, Sioud M (2020)
    Improving Dendritic Cell Cancer Vaccine Potency Using RNA Interference
    Methods Mol Biol, 2115, 249-258
    DOI 10.1007/978-1-0716-0290-4_14, PubMed 32006405
  205. Skotland T, Sagini K, Sandvig K, Llorente A (2020)
    An emerging focus on lipids in extracellular vesicles
    Adv Drug Deliv Rev, 159, 308-321
    DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
  206. Lampignano R, Neumann MHD, Weber S, Kloten V, Herdean A, Voss T, Groelz D, Babayan A, Tibbesma M, Schlumpberger M, Chemi F, Rothwell DG, Wikman H, Galizzi JP, Riise Bergheim I, Russnes H, Mussolin B, Bonin S, Voigt C, Musa H, Pinzani P, Lianidou E, Brady G, Speicher MR, Pantel K et al. (2020)
    Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows
    Clin Chem, 66 (1), 149-160
    DOI 10.1373/clinchem.2019.306837, PubMed 31628139
  207. Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, Pooley KA, Dennis J, Michailidou K, Turman C, Soucy P, Lemaçon A, Lush M, Tyrer JP, Ghoussaini M, Moradi Marjaneh M, Jiang X, Agata S, Aittomäki K, Alonso MR, Andrulis IL, Anton-Culver H, Antonenkova NN, Arason A, Arndt V et al. (2020)
    Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
    Nat Genet, 52 (1), 56-73
    DOI 10.1038/s41588-019-0537-1, PubMed 31911677
  208. Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
    Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
    Cancer Immunol Immunother, 69 (1), 159-161
    DOI 10.1007/s00262-019-02409-6, PubMed 31776597
  209. Casey NP, Kyte JA, Fujiwara H (2020)
    Use of RNA Interference with TCR Transfer to Enhance Safety and Efficiency
    Methods Mol Biol, 2115, 327-349
    DOI 10.1007/978-1-0716-0290-4_18, PubMed 32006409
  210. Evers M, Ten Broeke T, Jansen JHM, Nederend M, Hamdan F, Reiding KR, Meyer S, Moerer P, Brinkman I, Rösner T, Lebbink RJ, Valerius T, Leusen JHW (2020)
    Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies
    MAbs, 12 (1), 1795505
    DOI 10.1080/19420862.2020.1795505, PubMed 32744145
  211. Bai B, Myklebust JH, Wälchli S (2020)
    Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology
    Methods Mol Biol, 2115, 445-454
    DOI 10.1007/978-1-0716-0290-4_25, PubMed 32006416
  212. Sioud M (2020)
    RNA and CRISPR Interferences: Past, Present, and Future Perspectives
    Methods Mol Biol, 2115, 1-22
    DOI 10.1007/978-1-0716-0290-4_1, PubMed 32006392
  213. Sioud M (2020)
    Optimized siRNA Delivery into Primary Immune Cells Using Electroporation
    Methods Mol Biol, 2115, 119-131
    DOI 10.1007/978-1-0716-0290-4_7, PubMed 32006398
  214. Mobergslien A, Sioud M (2020)
    Exploring 5'-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency
    Methods Mol Biol, 2115, 163-170
    DOI 10.1007/978-1-0716-0290-4_9, PubMed 32006400
  215. Sioud M (2020)
    Unleashing the Therapeutic Potential of Dendritic and T Cell Therapies Using RNA Interference
    Methods Mol Biol, 2115, 259-280
    DOI 10.1007/978-1-0716-0290-4_15, PubMed 32006406
  216. Iversen PO, Sioud M (2020)
    Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy
    Methods Mol Biol, 2115, 281-287
    DOI 10.1007/978-1-0716-0290-4_16, PubMed 32006407
  217. Wälchli S, Sioud M (2020)
    Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?
    Methods Mol Biol, 2115, 407-417
    DOI 10.1007/978-1-0716-0290-4_22, PubMed 32006413
  218. Stenberg VY, Juzeniene A, Bruland ØS, Larsen RH (2020)
    In situ Generated 212Pb-PSMA Ligand in a 224Ra-Solution for Dual Targeting of Prostate Cancer Sclerotic Stroma and PSMA-positive Cells
    Curr Radiopharm, 13 (2), 130-141
    DOI 10.2174/1874471013666200511000532, PubMed 32389119
  219. Flem-Karlsen K, Fodstad Ø, Nunes-Xavier CE (2020)
    B7-H3 Immune Checkpoint Protein in Human Cancer
    Curr Med Chem, 27 (24), 4062-4086
    DOI 10.2174/0929867326666190517115515, PubMed 31099317
  220. Meltzer S, Bjørnetrø T, Lyckander LG, Flatmark K, Dueland S, Samiappan R, Johansen C, Kalanxhi E, Ree AH, Redalen KR (2020)
    Corrigendum to "Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer" [Transl Oncol 12 (8) (2019) 1038-1044]
    Transl Oncol, 13 (1), 122-124
    DOI 10.1016/j.tranon.2019.09.005, PubMed 31843135

Publications 2019

  1. Bains SJ, Abrahamsson H, Flatmark K, Dueland S, Hole KH, Seierstad T, Redalen KR, Meltzer S, Ree AH (2019)
    Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
    Cancer Immunol Immunother, 69 (3), 355-364
    DOI 10.1007/s00262-019-02458-x, PubMed 31893287
  2. Helgeland H, Sodeland M, Zoric N, Torgersen JS, Grammes F, von Lintig J, Moen T, Kjøglum S, Lien S, Våge DI (2019)
    Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color
    Sci Rep, 9 (1), 20061
    DOI 10.1038/s41598-019-56438-3, PubMed 31882713
  3. Olsen CE, Cheung LH, Weyergang A, Berg K, Vallera DA, Rosenblum MG, Selbo PK (2019)
    Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization
    J Clin Med, 9 (1)
    DOI 10.3390/jcm9010068, PubMed 31888091
  4. Andersson Y, Inderberg EM, Kvalheim G, Herud TM, Engebraaten O, Flatmark K, Dueland S, Fodstad Ø (2019)
    Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients
    Acta Oncol, 59 (4), 404-409
    DOI 10.1080/0284186X.2019.1704864, PubMed 31876430
  5. Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P (2019)
    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
    Cell Rep, 29 (13), 4389-4406.e10
    DOI 10.1016/j.celrep.2019.11.085, PubMed 31875548
  6. Palomo-Guerrero M, Fadó R, Casas M, Pérez-Montero M, Baena M, Helmer PO, Domínguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N (2019)
    Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
    Elife, 8
    DOI 10.7554/eLife.51063, PubMed 31868590
  7. Flem-Karlsen K, McFadden E, Omar N, Haugen MH, Øy GF, Ryder T, Gullestad HP, Hermann R, Mælandsmo GM, Flørenes VA (2019)
    Targeting AXL and the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Melanoma
    Mol Cancer Ther, 19 (3), 895-905
    DOI 10.1158/1535-7163.MCT-19-0290, PubMed 31871265
  8. Pitman KE, Bakke KM, Kristian A, Malinen E (2019)
    Ultra-early changes in vascular parameters from dynamic contrast enhanced MRI of breast cancer xenografts following systemic therapy with doxorubicin and liver X receptor agonist
    Cancer Imaging, 19 (1), 88
    DOI 10.1186/s40644-019-0280-y, PubMed 31856923
  9. Nunes-Xavier CE, Aurtenetxe O, Zaldumbide L, López-Almaraz R, Erramuzpe A, Cortés JM, López JI, Pulido R (2019)
    Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma
    Diagn Pathol, 14 (1), 134
    DOI 10.1186/s13000-019-0919-9, PubMed 31837707
  10. Lunde NN, Gregersen I, Ueland T, Shetelig C, Holm S, Kong XY, Michelsen AE, Otterdal K, Yndestad A, Broch K, Gullestad L, Nyman TA, Bendz B, Eritsland J, Hoffmann P, Skagen K, Gonçalves I, Nilsson J, Grenegård M, Poreba M, Drag M, Seljeflot I, Sporsheim B, Espevik T, Skjelland M et al. (2019)
    Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
    Atherosclerosis, 296, 74-82
    DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625
  11. Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nähse V, Jaszczyszyn Y, Lachages AM, Dutrillaux B, Thermes C, Debatisse M, Chen CL (2019)
    Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
    Nat Commun, 10 (1), 5693
    DOI 10.1038/s41467-019-13674-5, PubMed 31836700
  12. Pichard A, Marcatili S, Karam J, Constanzo J, Ladjohounlou R, Courteau A, Jarlier M, Bonnefoy N, Patzke S, Stenberg V, Coopman P, Cartron G, Navarro-Teulon I, Repetto-Llamazares A, Heyerdahl H, Dahle J, Bardiès M, Pouget JP (2019)
    The therapeutic effectiveness of 177Lu-lilotomab in B-cell non-Hodgkin lymphoma involves modulation of G2/M cell cycle arrest
    Leukemia, 34 (5), 1315-1328
    DOI 10.1038/s41375-019-0677-4, PubMed 31836849
  13. Brunsell TH, Sveen A, Bjørnbeth BA, Røsok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA (2019)
    High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
    Clin Colorectal Cancer, 19 (1), e26-e47
    DOI 10.1016/j.clcc.2019.09.003, PubMed 31982351
  14. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Holth A, Capella G, Davidson B, Evans DG, Martins A, Møller P, Hovig E (2019)
    Results of multigene panel testing in familial cancer cases without genetic cause demonstrated by single gene testing
    Sci Rep, 9 (1), 18555
    DOI 10.1038/s41598-019-54517-z, PubMed 31811167
  15. Sampson JR, Dominguez-Valentin M, Seppälä TT, Møller P (2019)
    Response to Tolva et al
    Genet Med, 22 (4), 813-814
    DOI 10.1038/s41436-019-0717-5, PubMed 31801985
  16. Saeednejad Zanjani L, Madjd Z, Rasti A, Asgari M, Abolhasani M, Tam KJ, Roudi R, Mælandsmo GM, Fodstad Ø, Andersson Y (2019)
    Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics
    Front Oncol, 9, 1302
    DOI 10.3389/fonc.2019.01302, PubMed 31921617
  17. Tekpli X, Lien T, Røssevold AH, Nebdal D, Borgen E, Ohnstad HO, Kyte JA, Vallon-Christersson J, Fongaard M, Due EU, Svartdal LG, Sveli MAT, Garred Ø, OSBREAC, Frigessi A, Sahlberg KK, Sørlie T, Russnes HG, Naume B, Kristensen VN (2019)
    An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
    Nat Commun, 10 (1), 5499
    DOI 10.1038/s41467-019-13329-5, PubMed 31796750
  18. Pashov A, Shivarov V, Hadzhieva M, Kostov V, Ferdinandov D, Heintz KM, Pashova S, Todorova M, Vassilev T, Kieber-Emmons T, Meza-Zepeda LA, Hovig E (2019)
    Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries
    Front Immunol, 10, 2796
    DOI 10.3389/fimmu.2019.02796, PubMed 31849974
  19. Overå KS, Garcia-Garcia J, Bhujabal Z, Jain A, Øvervatn A, Larsen KB, Deretic V, Johansen T, Lamark T, Sjøttem E (2019)
    TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1
    J Cell Sci, 132 (23)
    DOI 10.1242/jcs.236596, PubMed 31685529
  20. Pulido R, Mingo J, Gaafar A, Nunes-Xavier CE, Luna S, Torices L, Angulo JC, López JI (2019)
    Precise Immunodetection of PTEN Protein in Human Neoplasia
    Cold Spring Harb Perspect Med, 9 (12)
    DOI 10.1101/cshperspect.a036293, PubMed 31501265
  21. Meltzer S, Bakke KM, Rød KL, Negård A, Flatmark K, Solbakken AM, Kristensen AT, Fuglestad AJ, Kersten C, Dueland S, Seierstad T, Hole KH, Lyckander LG, Larsen FO, Schou JV, Patrick Brown D, Abrahamsson H, Redalen KR, Ree AH (2019)
    Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?
    Clin Transl Radiat Oncol, 21, 5-10
    DOI 10.1016/j.ctro.2019.11.006, PubMed 31872084
  22. Swanson DM, Lien T, Bergholtz H, Sørlie T, Frigessi A (2019)
    A Bayesian two-way latent structure model for genomic data integration reveals few pan-genomic cluster subtypes in a breast cancer cohort
    Bioinformatics, 35 (23), 4886-4897
    DOI 10.1093/bioinformatics/btz381, PubMed 31077301
  23. Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Abate D, Abbasi N, Abbastabar H, Abd-Allah F, Abdel-Rahman O, Abdelalim A, Abdoli A, Abdollahpour I, Abdulle ASM, Abebe ND, Abraha HN, Abu-Raddad LJ, Abualhasan A, Adedeji IA, Advani SM, Afarideh M, Afshari M, Aghaali M, Agius D, Agrawal S, Ahmadi A, Ahmadian E, Ahmadpour E et al. (2019)
    Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study
    JAMA Oncol, 5 (12), 1749-1768
    DOI 10.1001/jamaoncol.2019.2996, PubMed 31560378
  24. Rødland GE, Melhus K, Generalov R, Gilani S, Bertoni F, Dahle J, Syljuåsen RG, Patzke S (2019)
    The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37-Targeted Radioimmunotherapy in Activated B Cell Like Diffuse Large B Cell Lymphoma Cell Lines
    Front Oncol, 9, 1301
    DOI 10.3389/fonc.2019.01301, PubMed 31850205
  25. Webb M, Manley K, Olivan M, Guldvik I, Palczynska M, Hurst R, Connell SP, Mills IG, Brewer DS, Mills R, Cooper CS, Clark J (2019)
    Methodology for the at-home collection of urine samples for prostate cancer detection
    Biotechniques, 68 (2), 65-71
    DOI 10.2144/btn-2019-0092, PubMed 31779479
  26. Menon U, Vedsted P, Zalounina Falborg A, Jensen H, Harrison S, Reguilon I, Barisic A, Bergin RJ, Brewster DH, Butler J, Brustugun OT, Bucher O, Cairnduff V, Gavin A, Grunfeld E, Harland E, Kalsi J, Knudsen AK, Lambe M, Law RJ, Lin Y, Malmberg M, Turner D, Neal RD, White V et al. (2019)
    Time intervals and routes to diagnosis for lung cancer in 10 jurisdictions: cross-sectional study findings from the International Cancer Benchmarking Partnership (ICBP)
    BMJ Open, 9 (11), e025895
    DOI 10.1136/bmjopen-2018-025895, PubMed 31776134
  27. Forthun RB, Hovland R, Schuster C, Puntervoll H, Brodal HP, Namløs HM, Aasheim LB, Meza-Zepeda LA, Gjertsen BT, Knappskog S, Straume O (2019)
    ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab
    Sci Rep, 9 (1), 17471
    DOI 10.1038/s41598-019-53917-5, PubMed 31767937
  28. Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE et al. (2019)
    NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
    Nat Commun, 10 (1), 5284
    DOI 10.1038/s41467-019-13172-8, PubMed 31754102
  29. Pfefferle A, Jacobs B, Netskar H, Ask EH, Lorenz S, Clancy T, Goodridge JP, Sohlberg E, Malmberg KJ (2019)
    Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
    Cell Rep, 29 (8), 2284-2294.e4
    DOI 10.1016/j.celrep.2019.10.058, PubMed 31747601
  30. Madssen TS, Cao MD, Pladsen AV, Ottestad L, Sahlberg KK, Bathen TF, Giskeødegård GF (2019)
    Historical Biobanks in Breast Cancer Metabolomics- Challenges and Opportunities
    Metabolites, 9 (11)
    DOI 10.3390/metabo9110278, PubMed 31766128
  31. Juraleviciute M, Pozniak J, Nsengimana J, Harland M, Randerson-Moor J, Wernhoff P, Bassarova A, Øy GF, Trøen G, Flørenes VA, Bishop DT, Herlyn M, Newton-Bishop J, Slipicevic A (2019)
    MX 2 is a novel regulator of cell cycle in melanoma cells
    Pigment Cell Melanoma Res, 33 (3), 446-457
    DOI 10.1111/pcmr.12837, PubMed 31660681
  32. Lien VT, Kristiansen MK, Pettersen S, Haugen MH, Olberg DE, Waaler J, Klaveness J (2019)
    Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation
    RSC Adv., 9 (63), 37092-37100
    DOI 10.1039/c9ra08954c
  33. Vietri M, Radulovic M, Stenmark H (2019)
    The many functions of ESCRTs
    Nat Rev Mol Cell Biol, 21 (1), 25-42
    DOI 10.1038/s41580-019-0177-4, PubMed 31705132
  34. Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    J Extracell Vesicles, 8 (1), 1684862
    DOI 10.1080/20013078.2019.1684862, PubMed 31762963
  35. Nygård S, Lingjærde OC, Caldas C, Hovig E, Børresen-Dale AL, Helland Å, Haakensen VD (2019)
    PathTracer: High-sensitivity detection of differential pathway activity in tumours
    Sci Rep, 9 (1), 16332
    DOI 10.1038/s41598-019-52529-3, PubMed 31704995
  36. Neckmann U, Wolowczyk C, Hall M, Almaas E, Ren J, Zhao S, Johannessen B, Skotheim RI, Bjørkøy G, Ten Dijke P, Holien T (2019)
    GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
    Cell Commun Signal, 17 (1), 140
    DOI 10.1186/s12964-019-0467-7, PubMed 31694641
  37. Namløs HM, Boye K, Meza-Zepeda LA (2019)
    Cell-free DNA in blood as a noninvasive insight into the sarcoma genome
    Mol Aspects Med, 72, 100827
    DOI 10.1016/j.mam.2019.10.004, PubMed 31703948
  38. Nguéa P A, Robertson J, Herrera MC, Chymkowitch P, Enserink JM (2019)
    Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
    J Biol Chem, 294 (49), 18784-18795
    DOI 10.1074/jbc.RA119.009721, PubMed 31676685
  39. Sveen A, Cremolini C, Dienstmann R (2019)
    Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes
    Ann Oncol, 30 (11), 1682-1685
    DOI 10.1093/annonc/mdz412, PubMed 31868904
  40. Mukhopadhyay UK, Oturkar CC, Adams C, Wickramasekera N, Bansal S, Medisetty R, Miller A, Swetzig WM, Silwal-Pandit L, Børresen-Dale AL, Creighton CJ, Park JH, Konduri SD, Mukhopadhyay A, Caradori A, Omilian A, Bshara W, Kaipparettu BA, Das GM (2019)
    TP53 Status as a Determinant of Pro- vs Anti-Tumorigenic Effects of Estrogen Receptor-Beta in Breast Cancer
    J Natl Cancer Inst, 111 (11), 1202-1215
    DOI 10.1093/jnci/djz051, PubMed 30990221
  41. Wise JF, Lawrence MS (2019)
    Huge whole-genome study of human metastatic cancers
    Nature, 575 (7781), 60-61
    DOI 10.1038/d41586-019-03123-0, PubMed 31690848
  42. Eilertsen IA, Moosavi SH, Strømme JM, Nesbakken A, Johannessen B, Lothe RA, Sveen A (2019)
    Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer
    Cancer Lett, 469, 246-255
    DOI 10.1016/j.canlet.2019.10.040, PubMed 31678167
  43. Burocziova M, Burdova K, Martinikova AS, Kasparek P, Kleiblova P, Danielsen SA, Borecka M, Jenikova G, Janečková L, Pavel J, Zemankova P, Schneiderova M, Schwarzova L, Ticha I, Sun XF, Jiraskova K, Liska V, Vodickova L, Vodicka P, Sedlacek R, Kleibl Z, Lothe RA, Korinek V, Macurek L (2019)
    Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
    Cell Death Dis, 10 (11), 818
    DOI 10.1038/s41419-019-2057-4, PubMed 31659152
  44. Lopes N, Bergsland CH, Bjørnslett M, Pellinen T, Svindland A, Nesbakken A, Almeida R, Lothe RA, David L, Bruun J (2019)
    Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
    Lab Invest, 100 (1), 120-134
    DOI 10.1038/s41374-019-0336-4, PubMed 31641225
  45. Tolios A, De Las Rivas J, Hovig E, Trouillas P, Scorilas A, Mohr T (2019)
    Computational approaches in cancer multidrug resistance research: Identification of potential biomarkers, drug targets and drug-target interactions
    Drug Resist Updat, 48, 100662
    DOI 10.1016/j.drup.2019.100662, PubMed 31927437
  46. Skånland SS, Cieślar-Pobuda A (2019)
    Off-label uses of drugs for depression
    Eur J Pharmacol, 865, 172732
    DOI 10.1016/j.ejphar.2019.172732, PubMed 31622593
  47. Dominguez-Valentin M, Seppälä TT, Sampson JR, Macrae F, Winship I, Evans DG, Scott RJ, Burn J, Möslein G, Bernstein I, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lindblom A, Plazzer JP, Tjandra D, Thomas H, Green K, Lalloo F, Crosbie EJ, Hill J, Capella G, Pineda M, Navarro M, Vidal JB et al. (2019)
    Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 28
    DOI 10.1186/s13053-019-0127-3, PubMed 31636762
  48. Napoli E, Cessna JT, Fitzgerald R, Pibida L, Collé R, Laureano-Pérez L, Zimmerman BE, Bergeron DE (2019)
    Primary standardization of 224Ra activity by liquid scintillation counting
    Appl Radiat Isot, 155, 108933
    DOI 10.1016/j.apradiso.2019.108933, PubMed 31654881
  49. Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
    Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
    Curr Biol, 29 (20), 3538-3548.e7
    DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
  50. Nome ME, Euceda LR, Jabeen S, Debik J, Bathen TF, Giskeødegård GF, Taskén KA, Maelandsmo GM, Halvorsen B, Yndestad A, Borgen E, Garred Ø, Aukrust P, Ueland T, Engebraaten O, Kristensen VN, Tekpli X (2019)
    Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
    Int J Cancer, 146 (1), 223-235
    DOI 10.1002/ijc.32638, PubMed 31444972
  51. Dillard C, Rusten TE (2019)
    Cell Competition Triggers Suicide by Autophagy
    Dev Cell, 51 (1), 4-5
    DOI 10.1016/j.devcel.2019.09.014, PubMed 31593651
  52. Dienstmann R, Villacampa G, Sveen A, Mason MJ, Niedzwiecki D, Nesbakken A, Moreno V, Warren RS, Lothe RA, Guinney J (2019)
    Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer
    Ann Oncol, 30 (10), 1622-1629
    DOI 10.1093/annonc/mdz287, PubMed 31504112
  53. Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
    Correction: Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
    Br J Cancer, 121 (9), 807
    DOI 10.1038/s41416-019-0590-7, PubMed 31548598
  54. Handle F, Prekovic S, Helsen C, Van den Broeck T, Smeets E, Moris L, Eerlings R, Kharraz SE, Urbanucci A, Mills IG, Joniau S, Attard G, Claessens F (2019)
    Drivers of AR indifferent anti-androgen resistance in prostate cancer cells
    Sci Rep, 9 (1), 13786
    DOI 10.1038/s41598-019-50220-1, PubMed 31551480
  55. Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV et al. (2019)
    Publisher Correction: Shared heritability and functional enrichment across six solid cancers
    Nat Commun, 10 (1), 4386
    DOI 10.1038/s41467-019-12095-8, PubMed 31548585
  56. Halvorsen AR, Ragle Aure M, Õjlert ÅK, Brustugun OT, Solberg S, Nebdal D, Helland Å (2019)
    Identification of microRNAs involved in pathways which characterize the expression subtypes of NSCLC
    Mol Oncol, 13 (12), 2604-2615
    DOI 10.1002/1878-0261.12571, PubMed 31505091
  57. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2019)
    Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of high-grade pseudomyxoma peritonei
    Clin Exp Metastasis, 36 (6), 511-518
    DOI 10.1007/s10585-019-09991-0, PubMed 31541325
  58. Carm KT, Hoff AM, Bakken AC, Axcrona U, Axcrona K, Lothe RA, Skotheim RI, Løvf M (2019)
    Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer
    Sci Rep, 9 (1), 13579
    DOI 10.1038/s41598-019-49964-7, PubMed 31537872
  59. Ha TJ, Zhang PGY, Robert R, Yeung J, Swanson DJ, Mathelier A, Wasserman WW, Im S, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E, FANTOM Consortium, Carninci P, Hayashizaki Y, Forrest ARR, Goldowitz D (2019)
    Identification of novel cerebellar developmental transcriptional regulators with motif activity analysis
    BMC Genomics, 20 (1), 718
    DOI 10.1186/s12864-019-6063-9, PubMed 31533632
  60. Debik J, Euceda LR, Lundgren S, Gythfeldt HVL, Garred Ø, Borgen E, Engebraaten O, Bathen TF, Giskeødegård GF (2019)
    Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients
    J Proteome Res, 18 (10), 3649-3660
    DOI 10.1021/acs.jproteome.9b00316, PubMed 31483662
  61. Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E et al. (2019)
    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
    Nat Commun, 10 (1), 4176
    DOI 10.1038/s41467-019-12094-9, PubMed 31519908
  62. Enqvist M, Jacobs B, Junlén HR, Schaffer M, Melén CM, Friberg D, Wahlin BE, Malmberg KJ (2019)
    Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma
    Front Immunol, 10, 2085
    DOI 10.3389/fimmu.2019.02085, PubMed 31572357
  63. Totland MZ, Rasmussen NL, Knudsen LM, Leithe E (2019)
    Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications
    Cell Mol Life Sci, 77 (4), 573-591
    DOI 10.1007/s00018-019-03285-0, PubMed 31501970
  64. Boye E, Grallert B (2019)
    eIF2α phosphorylation and the regulation of translation
    Curr Genet, 66 (2), 293-297
    DOI 10.1007/s00294-019-01026-1, PubMed 31485739
  65. Grigalavicius M, Mastrangelopoulou M, Berg K, Arous D, Ménard M, Raabe-Henriksen T, Brondz E, Siem S, Görgen A, Edin NFJ, Malinen E, Theodossiou TA (2019)
    Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
    Nat Commun, 10 (1), 3986
    DOI 10.1038/s41467-019-12042-7, PubMed 31484929
  66. Pielke R, Tucker R, Boye E (2019)
    Scientific integrity and the IAAF testosterone regulations (vol 19, pg 18, 2019)
    Int. Sports Law J., 19 (1-2), 27-28
    DOI 10.1007/s40318-019-00149-4
  67. Pielke R, Tucker R, Boye E (2019)
    Scientific integrity and the IAAF testosterone regulations
    Int. Sports Law J., 19 (1-2), 18-26
    DOI 10.1007/s40318-019-00143-w
  68. Skånland SS, Cremaschi A, Bendiksen H, Hermansen JU, Thimiri Govinda Raj DB, Munthe LA, Tjønnfjord GE, Taskén K (2019)
    An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
    Leukemia, 34 (2), 478-487
    DOI 10.1038/s41375-019-0569-7, PubMed 31471562
  69. Dörk T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q, Dennis J, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Freeman LEB, Beckmann MW, Beeghly-Fadiel A, Behrens S, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Burwinkel B, Canzian F, Chan TL et al. (2019)
    Two truncating variants in FANCC and breast cancer risk
    Sci Rep, 9 (1), 12524
    DOI 10.1038/s41598-019-48804-y, PubMed 31467304
  70. Gaustad JV, Simonsen TG, Wegner CS, Rofstad EK (2019)
    Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts
    Front Oncol, 9, 845
    DOI 10.3389/fonc.2019.00845, PubMed 31555596
  71. Lindholm EM, Ragle Aure M, Haugen MH, Kleivi Sahlberg K, Kristensen VN, Nebdal D, Børresen-Dale AL, Lingjaerde OC, Engebraaten O (2019)
    miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer
    Mol Oncol, 13 (10), 2278-2296
    DOI 10.1002/1878-0261.12561, PubMed 31402562
  72. Pölönen P, Jawahar Deen A, Leinonen HM, Jyrkkänen HK, Kuosmanen S, Mononen M, Jain A, Tuomainen T, Pasonen-Seppänen S, Hartikainen JM, Mannermaa A, Nykter M, Tavi P, Johansen T, Heinäniemi M, Levonen AL (2019)
    Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
    Oncogene, 38 (50), 7473-7490
    DOI 10.1038/s41388-019-0956-6, PubMed 31444413
  73. Gheorghe M, Sandve GK, Khan A, Chèneby J, Ballester B, Mathelier A (2019)
    A map of direct TF-DNA interactions in the human genome
    Nucleic Acids Res, 47 (14), 7715
    DOI 10.1093/nar/gkz582, PubMed 31251803
  74. Dong X, Zhang R, He J, Lai L, Alolga RN, Shen S, Zhu Y, You D, Lin L, Chen C, Zhao Y, Duan W, Su L, Shafer A, Salama M, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Wang R, Staaf J, Helland Å, Esteller M, Wei Y, Chen F et al. (2019)
    Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma
    Aging (Albany NY), 11 (16), 6312-6335
    DOI 10.18632/aging.102189, PubMed 31434796
  75. Alcala N, Leblay N, Gabriel AAG, Mangiante L, Hervas D, Giffon T, Sertier AS, Ferrari A, Derks J, Ghantous A, Delhomme TM, Chabrier A, Cuenin C, Abedi-Ardekani B, Boland A, Olaso R, Meyer V, Altmuller J, Le Calvez-Kelm F, Durand G, Voegele C, Boyault S, Moonen L, Lemaitre N, Lorimier P et al. (2019)
    Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids
    Nat Commun, 10 (1), 3407
    DOI 10.1038/s41467-019-11276-9, PubMed 31431620
  76. Della Valle A, Rossi BM, Palmero EI, Antelo M, Vaccaro CA, López-Kostner F, Alvarez K, Cruz-Correa M, Bruno LI, Forones NM, Mindiola JAR, Buleje J, Spirandelli F, Bohorquez M, Cock-Rada AM, Sullcahuaman Y, Nascimento I, Abe-Sandes K, Lino-Silva LS, Petracchi F, Mampel A, Rodriguez Y, Rossi NT, Yañez CB, Rubio C et al. (2019)
    A snapshot of current genetic testing practice in Lynch syndrome: The results of a representative survey of 33 Latin American existing centres/registries
    Eur J Cancer, 119, 112-121
    DOI 10.1016/j.ejca.2019.07.017, PubMed 31442815
  77. Lien VT, Pettersen S, Haugen MH, Olberg DE, Maelandsmo GM, Klaveness J (2019)
    Design, synthesis and biological evaluation of 6-substituted quinolines derived from cabozantinib as c-Met inhibitors
    Arch Pharm (Weinheim), 352 (9), e1900101
    DOI 10.1002/ardp.201900101, PubMed 31414521
  78. Sneeggen M, Schink KO, Stenmark H (2019)
    Tumor suppression by control of matrix metalloproteinase recycling
    Mol Cell Oncol, 6 (6), e1646606
    DOI 10.1080/23723556.2019.1646606, PubMed 31692886
  79. Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
    Cell Rep, 28 (7), 1907-1922.e6
    DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255
  80. Ruoff P, Agafonov O, Tveit DM, Thorsen K, Drengstig T (2019)
    Homeostatic controllers compensating for growth and perturbations
    PLoS One, 14 (8), e0207831
    DOI 10.1371/journal.pone.0207831, PubMed 31404092
  81. Braadland PR, Ramberg H, Grytli HH, Urbanucci A, Nielsen HK, Guldvik IJ, Engedal A, Ketola K, Wang W, Svindland A, Mills IG, Bjartell A, Taskén KA (2019)
    The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells
    Mol Cancer Res, 17 (11), 2154-2168
    DOI 10.1158/1541-7786.MCR-18-0605, PubMed 31395667
  82. Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
    Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
    Br J Cancer, 121 (6), 474-482
    DOI 10.1038/s41416-019-0540-4, PubMed 31388185
  83. Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
    Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
    Int J Nanomedicine, 14, 6269-6285
    DOI 10.2147/IJN.S208938, PubMed 31496685
  84. Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
    ESCRT-mediated phagophore sealing during mitophagy
    Autophagy, 16 (5), 826-841
    DOI 10.1080/15548627.2019.1639301, PubMed 31366282
  85. Hausken J, Fretland ÅA, Edwin B, Andersen MH, Dagenborg VJ, Bjørnelv GMW, Kristiansen R, Røysland K, Kvarstein G, Tønnessen TI (2019)
    Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
    Ann Surg, 270 (2), 193-199
    DOI 10.1097/SLA.0000000000003209, PubMed 30676382
  86. Fougner C, Bergholtz H, Kuiper R, Norum JH, Sørlie T (2019)
    Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers
    Breast Cancer Res, 21 (1), 85
    DOI 10.1186/s13058-019-1170-8, PubMed 31366361
  87. Sioud M, Pettersen S, Ailte I, Fløisand Y (2019)
    Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
    Cancers (Basel), 11 (8)
    DOI 10.3390/cancers11081088, PubMed 31370273
  88. Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
    5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
    Sci Rep, 9 (1), 11065
    DOI 10.1038/s41598-019-47528-3, PubMed 31363131
  89. Malt EA, Juhasz K, Frengen A, Wangensteen T, Emilsen NM, Hansen B, Agafonov O, Nilsen HL (2019)
    Neuropsychiatric phenotype in relation to gene variants in the hemizygous allele in 3q29 deletion carriers: A case series
    Mol Genet Genomic Med, 7 (9), e889
    DOI 10.1002/mgg3.889, PubMed 31347308
  90. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2019)
    Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (1), 15-25
    DOI 10.1038/s41436-019-0596-9, PubMed 31337882
  91. Richardsen E, Andersen S, Al-Saad S, Rakaee M, Nordby Y, Pedersen MI, Ness N, Ingebriktsen LM, Fassina A, Taskén KA, Mills IG, Donnem T, Bremnes RM, Busund LT (2019)
    Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer
    Sci Rep, 9 (1), 10662
    DOI 10.1038/s41598-019-47234-0, PubMed 31337863
  92. Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
    Resident memory CD8 T cells persist for years in human small intestine
    J Exp Med, 216 (10), 2412-2426
    DOI 10.1084/jem.20190414, PubMed 31337737
  93. Fretland ÅA, Dagenborg VJ, Waaler Bjørnelv GM, Aghayan DL, Kazaryan AM, Barkhatov L, Kristiansen R, Fagerland MW, Edwin B, Andersen MH (2019)
    Quality of life from a randomized trial of laparoscopic or open liver resection for colorectal liver metastases
    Br J Surg, 106 (10), 1372-1380
    DOI 10.1002/bjs.11227, PubMed 31322735
  94. Brunsell TH, Cengija V, Sveen A, Bjørnbeth BA, Røsok BI, Brudvik KW, Guren MG, Lothe RA, Abildgaard A, Nesbakken A (2019)
    Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
    Eur J Surg Oncol, 45 (12), 2340-2346
    DOI 10.1016/j.ejso.2019.07.017, PubMed 31350075
  95. Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, Jin Y, Koc D, Kuzu OF, Pradhan M, Danielsen HE, Kahraman N, Mokhlis HM, Ozpolat B, Banerjee PP, Uren A, Fazli L, Rennie PS, Jin Y, Saatcioglu F (2019)
    Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer
    Oncogene, 38 (35), 6301-6318
    DOI 10.1038/s41388-019-0879-2, PubMed 31312022
  96. Berg KCG, Sveen A, Høland M, Alagaratnam S, Berg M, Danielsen SA, Nesbakken A, Søreide K, Lothe RA (2019)
    Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
    Oncogene, 38 (33), 6109-6122
    DOI 10.1038/s41388-019-0868-5, PubMed 31308487
  97. Olweus J, Lund-Johansen F (2019)
    Finding Neo (antigens, that is)
    Blood, 134 (2), 108-109
    DOI 10.1182/blood.2019001334, PubMed 31296544
  98. Skånland SS, Taskén K (2019)
    Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling
    J Immunol, 203 (4), 1055-1063
    DOI 10.4049/jimmunol.1801660, PubMed 31292214
  99. Sveen A, Kopetz S, Lothe RA (2019)
    Biomarker-guided therapy for colorectal cancer: strength in complexity
    Nat Rev Clin Oncol, 17 (1), 11-32
    DOI 10.1038/s41571-019-0241-1, PubMed 31289352
  100. Norum JH, Frings O, Kasper M, Bergholtz H, Zell Thime H, Bergström Å, Andersson A, Kuiper R, Fredlund E, Sørlie T, Toftgård R (2019)
    GLI1-induced mammary gland tumours are transplantable and maintain major molecular features
    Int J Cancer, 146 (4), 1125-1138
    DOI 10.1002/ijc.32522, PubMed 31219615
  101. Visnovska T, Biggs PJ, Schmeier S, Frizelle FA, Purcell RV (2019)
    Metagenomics and transcriptomics data from human colorectal cancer
    Sci Data, 6 (1), 116
    DOI 10.1038/s41597-019-0117-3, PubMed 31278253
  102. Calvete J, Larrinaga G, Errarte P, Martín AM, Dotor A, Esquinas C, Nunes-Xavier CE, Pulido R, López JI, Angulo JC (2019)
    The coexpression of fibroblast activation protein (FAP) and basal-type markers (CK 5/6 and CD44) predicts prognosis in high-grade invasive urothelial carcinoma of the bladder
    Hum Pathol, 91, 61-68
    DOI 10.1016/j.humpath.2019.07.002, PubMed 31279874
  103. Dukic AR, Gerbaud P, Guibourdenche J, Thiede B, Taskén K, Pidoux G (2019)
    Correction: Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion
    Biochem J, 476 (13), 1927
    DOI 10.1042/BCJ-2017-0529_COR, PubMed 31266855
  104. Hamfjord J, Guren TK, Dajani O, Johansen JS, Glimelius B, Sorbye H, Pfeiffer P, Lingjærde OC, Tveit KM, Kure EH, Pallisgaard N, Spindler KG (2019)
    Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy
    Ann Oncol, 30 (7), 1088-1095
    DOI 10.1093/annonc/mdz139, PubMed 31046124
  105. Pitman KE, Alluri SR, Kristian A, Aarnes EK, Lyng H, Riss PJ, Malinen E (2019)
    Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts
    Eur J Nucl Med Mol Imaging, 46 (10), 2190-2198
    DOI 10.1007/s00259-019-04375-8, PubMed 31264167
  106. Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
    WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
    Nat Commun, 10 (1), 2850
    DOI 10.1038/s41467-019-10794-w, PubMed 31253801
  107. Jerjes W, Hamdoon Z, Berg K, Høgset A, Hopper C (2019)
    Recurrent chondroblastic osteosarcoma of the right mandible subjected to photochemical internalization
    Photodiagnosis Photodyn Ther, 27, 288-290
    DOI 10.1016/j.pdpdt.2019.06.018, PubMed 31252139
  108. Smeby J, Sveen A, Bergsland CH, Eilertsen IA, Danielsen SA, Eide PW, Hektoen M, Guren MG, Nesbakken A, Bruun J, Lothe RA (2019)
    Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
    ESMO Open, 4 (3), e000523
    DOI 10.1136/esmoopen-2019-000523, PubMed 31321083
  109. Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T (2019)
    The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
    Sci Rep, 9 (1), 9206
    DOI 10.1038/s41598-019-45651-9, PubMed 31235849
  110. Skotland T, Sandvig K (2019)
    The role of PS 18:0/18:1 in membrane function
    Nat Commun, 10 (1), 2752
    DOI 10.1038/s41467-019-10711-1, PubMed 31227693
  111. Cornillet M, Jansson H, Schaffer M, Hertwig L, Berglin L, Zimmer CL, Johansson H, Ellis E, Isaksson B, Gonzalez-Galarza FF, Middleton D, Malmberg KJ, Sparrelid E, Björkström NK (2019)
    Imbalance of Genes Encoding Natural Killer Immunoglobulin-Like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer
    Gastroenterology, 157 (4), 1067-1080.e9
    DOI 10.1053/j.gastro.2019.06.023, PubMed 31229495
  112. Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M (2019)
    Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
    Toxins (Basel), 11 (6)
    DOI 10.3390/toxins11060350, PubMed 31216687
  113. Anda S, Grallert B (2019)
    Cell-Cycle-Dependent Regulation of Translation: New Interpretations of Old Observations in Light of New Approaches
    Bioessays, 41 (8), e1900022
    DOI 10.1002/bies.201900022, PubMed 31210378
  114. Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2019)
    Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
    Cancer Immunol Immunother, 68 (8), 1235-1243
    DOI 10.1007/s00262-019-02356-2, PubMed 31214732
  115. Lilleborge M, Falk RS, Russnes H, Sauer T, Ursin G, Hofvind S (2019)
    Risk of breast cancer by prior screening results among women participating in BreastScreen Norway
    Cancer, 125 (19), 3330-3337
    DOI 10.1002/cncr.32330, PubMed 31206638
  116. Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J et al. (2019)
    Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
    Nat Commun, 10 (1), 2674
    DOI 10.1038/s41467-019-09799-2, PubMed 31209238
  117. Marcuello M, Vymetalkova V, Neves RPL, Duran-Sanchon S, Vedeld HM, Tham E, van Dalum G, Flügen G, Garcia-Barberan V, Fijneman RJ, Castells A, Vodicka P, Lind GE, Stoecklein NH, Heitzer E, Gironella M (2019)
    Circulating biomarkers for early detection and clinical management of colorectal cancer
    Mol Aspects Med, 69, 107-122
    DOI 10.1016/j.mam.2019.06.002, PubMed 31189073
  118. Solvang HK, Subbey S (2019)
    Correction: An improved methodology for quantifying causality in complex ecological systems
    PLoS One, 14 (6), e0217195
    DOI 10.1371/journal.pone.0217195, PubMed 31185025
  119. Vaclavikova R, Klajic J, Brynychova V, Elsnerova K, Alnaes GIG, Tost J, Kristensen VN, Rob L, Kodet R, Skapa P, Mrhalova M, Soucek P (2019)
    Development of high‑resolution melting analysis for ABCB1 promoter methylation: Clinical consequences in breast and ovarian carcinoma
    Oncol Rep, 42 (2), 763-774
    DOI 10.3892/or.2019.7186, PubMed 31173253
  120. Hansem LMK, Huang R, Wegner CS, Simonsen TG, Gaustad JV, Hauge A, Rofstad EK (2019)
    Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and Pancreatic Carcinoma Xenografts
    Transl Oncol, 12 (8), 1079-1085
    DOI 10.1016/j.tranon.2019.05.012, PubMed 31174058
  121. Mesquita P, Freire AF, Lopes N, Gomes R, Azevedo D, Barros R, Pereira B, Cavadas B, Pópulo H, Boaventura P, David L, Pereira L, Almeida R (2019)
    Expression and Clinical Relevance of SOX9 in Gastric Cancer
    Dis Markers, 2019, 8267021
    DOI 10.1155/2019/8267021, PubMed 31275454
  122. Shu X, Wu L, Khankari NK, Shu XO, Wang TJ, Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah PDP, Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W, Breast Cancer Association Consortium (2019)
    Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis
    Int J Epidemiol, 48 (3), 795-806
    DOI 10.1093/ije/dyy201, PubMed 30277539
  123. Njølstad PR, Andreassen OA, Brunak S, Børglum AD, Dillner J, Esko T, Franks PW, Freimer N, Groop L, Heimer H, Hougaard DM, Hovig E, Hveem K, Jalanko A, Kaprio J, Knudsen GP, Melbye M, Metspalu A, Mortensen PB, Palmgren J, Palotie A, Reed W, Stefánsson H, Stitziel NO, Sullivan PF et al. (2019)
    Roadmap for a precision-medicine initiative in the Nordic region
    Nat Genet, 51 (6), 924-930
    DOI 10.1038/s41588-019-0391-1, PubMed 30988515
  124. Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Trøseid M, Dyrhol-Riise AM (2019)
    Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
    AIDS, 33 (7), 1117-1129
    DOI 10.1097/QAD.0000000000002173, PubMed 30789356
  125. Larsen LK, Lind GE, Guldberg P, Dahl C (2019)
    DNA-Methylation-Based Detection of Urological Cancer in Urine: Overview of Biomarkers and Considerations on Biomarker Design, Source of DNA, and Detection Technologies
    Int J Mol Sci, 20 (11)
    DOI 10.3390/ijms20112657, PubMed 31151158
  126. Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
    Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
    Cells, 8 (6)
    DOI 10.3390/cells8060518, PubMed 31146385
  127. Meltzer S, Bjørnetrø T, Lyckander LG, Flatmark K, Dueland S, Samiappan R, Johansen C, Kalanxhi E, Ree AH, Redalen KR (2019)
    Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
    Transl Oncol, 12 (8), 1038-1044
    DOI 10.1016/j.tranon.2019.04.014, PubMed 31146167
  128. Abrahamsson H, Porojnicu AC, Lindstrøm JC, Dueland S, Flatmark K, Hole KH, Seierstad T, Moan J, Redalen KR, Meltzer S, Ree AH (2019)
    High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
    BMC Cancer, 19 (1), 488
    DOI 10.1186/s12885-019-5724-z, PubMed 31122213
  129. Lai X, Geier OM, Fleischer T, Garred Ø, Borgen E, Funke SW, Kumar S, Rognes ME, Seierstad T, Børresen-Dale AL, Kristensen VN, Engebraaten O, Köhn-Luque A, Frigessi A (2019)
    Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
    Cancer Res, 79 (16), 4293-4304
    DOI 10.1158/0008-5472.CAN-18-1804, PubMed 31118201
  130. Mauseth B, Camilio KA, Shi J, Hammarström CL, Rekdal Ø, Sveinbjørnsson B, Line PD (2019)
    The Novel Oncolytic Compound LTX-401 Induces Antitumor Immune Responses in Experimental Hepatocellular Carcinoma
    Mol Ther Oncolytics, 14, 139-148
    DOI 10.1016/j.omto.2019.05.002, PubMed 31211244
  131. Ali M, Foldvari Z, Giannakopoulou E, Böschen ML, Strønen E, Yang W, Toebes M, Schubert B, Kohlbacher O, Schumacher TN, Olweus J (2019)
    Induction of neoantigen-reactive T cells from healthy donors
    Nat Protoc, 14 (6), 1926-1943
    DOI 10.1038/s41596-019-0170-6, PubMed 31101906
  132. Tomescu-Baciu A, Johansen JN, Holmøy T, Greiff V, Stensland M, de Souza GA, Vartdal F, Lossius A (2019)
    Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis
    J Neuroimmunol, 333, 576966
    DOI 10.1016/j.jneuroim.2019.576966, PubMed 31153015
  133. Smeby J, Sveen A, Eilertsen IA, Danielsen SA, Hoff AM, Eide PW, Johannessen B, Hektoen M, Skotheim RI, Guren MG, Nesbakken A, Lothe RA (2019)
    Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
    Oncogenesis, 8 (6), 35
    DOI 10.1038/s41389-019-0141-3, PubMed 31092812
  134. Grinde MT, Hilmarsdottir B, Tunset HM, Henriksen IM, Kim J, Haugen MH, Rye MB, Mælandsmo GM, Moestue SA (2019)
    Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer
    Breast Cancer Res, 21 (1), 61
    DOI 10.1186/s13058-019-1141-0, PubMed 31088535
  135. Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
    A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
    Transl Oncol, 12 (7), 951-958
    DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111
  136. Ackermann F, Schink KO, Bruns C, Izsvák Z, Hamra FK, Rosenmund C, Garner CC (2019)
    Critical role for Piccolo in synaptic vesicle retrieval
    Elife, 8
    DOI 10.7554/eLife.46629, PubMed 31074746
  137. Shin D, Nguyen L, T Le M, Ju D, N Le J, Berg K, Hirschberg H (2019)
    The effects of low irradiance long duration photochemical internalization on glioma spheroids
    Photodiagnosis Photodyn Ther, 26, 442-447
    DOI 10.1016/j.pdpdt.2019.05.005, PubMed 31075319
  138. Huse K (2019)
    Expanding the Clinical Cytometry Toolbox-Receptor Occupancy by Mass Cytometry
    Cytometry A, 95 (10), 1046-1048
    DOI 10.1002/cyto.a.23784, PubMed 31046178
  139. Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica, 104 (5), e229
    DOI 10.3324/haematol.2019.220533, PubMed 31040234
  140. Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2019)
    Colocalization analyses of genomic elements: approaches, recommendations and challenges
    Bioinformatics, 35 (9), 1615-1624
    DOI 10.1093/bioinformatics/bty835, PubMed 30307532
  141. Sandhu V, Labori KJ, Borgida A, Lungu I, Bartlett J, Hafezi-Bakhtiari S, Denroche RE, Jang GH, Pasternack D, Mbaabali F, Watson M, Wilson J, Kure EH, Gallinger S, Haibe-Kains B (2019)
    Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma
    JCO Clin Cancer Inform, 3, 1-16
    DOI 10.1200/CCI.18.00102, PubMed 31070984
  142. Brynildsen J, Petäjä L, Myhre PL, Lyngbakken MN, Nygård S, Stridsberg M, Christensen G, Ottesen AH, Pettilä V, Omland T, Røsjø H (2019)
    Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
    Crit Care Med, 47 (5), e412-e419
    DOI 10.1097/CCM.0000000000003670, PubMed 30730440
  143. Köksal H, Dillard P, Josefsson SE, Maggadottir SM, Pollmann S, Fåne A, Blaker YN, Beiske K, Huse K, Kolstad A, Holte H, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2019)
    Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
    Blood Adv, 3 (8), 1230-1243
    DOI 10.1182/bloodadvances.2018029678, PubMed 30979721
  144. Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2019)
    ImmunoPeCa trial: Long-term outcome following intraperitoneal MOC31PE immunotoxin treatment in colorectal peritoneal metastasis
    Eur J Surg Oncol, 47 (1), 134-138
    DOI 10.1016/j.ejso.2019.04.014, PubMed 31036394
  145. Hausott B, Förste A, Zach F, Mangger S, Haugsten EM, Klimaschewski L (2019)
    Endocytosis and Transport of Growth Factor Receptors in Peripheral Axon Regeneration: Novel Lessons from Neurons Expressing Lysine-Deficient FGF Receptor Type 1 in vitro
    Anat Rec (Hoboken), 302 (8), 1268-1275
    DOI 10.1002/ar.24120, PubMed 30950230
  146. Miranda A, Hamilton PT, Zhang AW, Pattnaik S, Becht E, Mezheyeuski A, Bruun J, Micke P, de Reynies A, Nelson BH (2019)
    Cancer stemness, intratumoral heterogeneity, and immune response across cancers
    Proc Natl Acad Sci U S A, 116 (18), 9020-9029
    DOI 10.1073/pnas.1818210116, PubMed 30996127
  147. Zhang R, Lai L, Dong X, He J, You D, Chen C, Lin L, Zhu Y, Huang H, Shen S, Wei L, Chen X, Guo Y, Liu L, Su L, Shafer A, Moran S, Fleischer T, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y et al. (2019)
    SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic-smoking interaction analysis
    Mol Oncol, 13 (5), 1235-1248
    DOI 10.1002/1878-0261.12482, PubMed 30924596
  148. Brinkman AB, Nik-Zainal S, Simmer F, Rodríguez-González FG, Smid M, Alexandrov LB, Butler A, Martin S, Davies H, Glodzik D, Zou X, Ramakrishna M, Staaf J, Ringnér M, Sieuwerts A, Ferrari A, Morganella S, Fleischer T, Kristensen V, Gut M, van de Vijver MJ, Børresen-Dale AL, Richardson AL, Thomas G, Gut IG et al. (2019)
    Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
    Nat Commun, 10 (1), 1749
    DOI 10.1038/s41467-019-09828-0, PubMed 30988298
  149. Ferreira MA, Gamazon ER, Al-Ejeh F, Aittomäki K, Andrulis IL, Anton-Culver H, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Azzollini J, Balmaña J, Barnes DR, Barrowdale D, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Białkowska K, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Borg A et al. (2019)
    Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
    Nat Commun, 10 (1), 1741
    DOI 10.1038/s41467-018-08053-5, PubMed 30988301
  150. Mingo J, Luna S, Gaafar A, Nunes-Xavier CE, Torices L, Mosteiro L, Ruiz R, Guerra I, Llarena R, Angulo JC, López JI, Pulido R (2019)
    Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology
    NPJ Precis Oncol, 3, 11
    DOI 10.1038/s41698-019-0083-4, PubMed 30993208
  151. Zakrzewska M, Opalinski L, Haugsten EM, Otlewski J, Wiedlocha A (2019)
    Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
    Int J Mol Sci, 20 (8)
    DOI 10.3390/ijms20081826, PubMed 31013829
  152. Itkonen HM, Urbanucci A, Martin SE, Khan A, Mathelier A, Thiede B, Walker S, Mills IG (2019)
    High OGT activity is essential for MYC-driven proliferation of prostate cancer cells
    Theranostics, 9 (8), 2183-2197
    DOI 10.7150/thno.30834, PubMed 31149037
  153. Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation
    Br J Cancer, 121 (1), 15-21
    DOI 10.1038/s41416-019-0446-1, PubMed 30971774
  154. Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
    Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
    NPJ Breast Cancer, 5, 13
    DOI 10.1038/s41523-019-0108-8, PubMed 30993194
  155. Öjlert ÅK, Halvorsen AR, Nebdal D, Lund-Iversen M, Solberg S, Brustugun OT, Lingjaerde OC, Helland Å (2019)
    The immune microenvironment in non-small cell lung cancer is predictive of prognosis after surgery
    Mol Oncol, 13 (5), 1166-1179
    DOI 10.1002/1878-0261.12475, PubMed 30854794
  156. Flem-Karlsen K, Tekle C, Øyjord T, Flørenes VA, Mælandsmo GM, Fodstad Ø, Nunes-Xavier CE (2019)
    p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
    Sci Rep, 9 (1), 5839
    DOI 10.1038/s41598-019-42303-w, PubMed 30967582
  157. Johansson HJ, Socciarelli F, Vacanti NM, Haugen MH, Zhu Y, Siavelis I, Fernandez-Woodbridge A, Aure MR, Sennblad B, Vesterlund M, Branca RM, Orre LM, Huss M, Fredlund E, Beraki E, Garred Ø, Boekel J, Sauer T, Zhao W, Nord S, Höglander EK, Jans DC, Brismar H, Haukaas TH, Bathen TF et al. (2019)
    Breast cancer quantitative proteome and proteogenomic landscape
    Nat Commun, 10 (1), 1600
    DOI 10.1038/s41467-019-09018-y, PubMed 30962452
  158. Barkovskaya A, Seip K, Hilmarsdottir B, Maelandsmo GM, Moestue SA, Itkonen HM (2019)
    O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes
    Sci Rep, 9 (1), 5670
    DOI 10.1038/s41598-019-42153-6, PubMed 30952976
  159. Aghayan DL, Fretland ÅA, Kazaryan AM, Sahakyan MA, Dagenborg VJ, Bjørnbeth BA, Flatmark K, Kristiansen R, Edwin B (2019)
    Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
    HPB (Oxford), 21 (11), 1485-1490
    DOI 10.1016/j.hpb.2019.03.358, PubMed 30962136
  160. Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC (2019)
    The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses
    J Pharmacol Exp Ther, 370 (3), 581-592
    DOI 10.1124/jpet.119.258012, PubMed 30940695
  161. Abravan A, Eide HA, Løndalen AM, Helland Å, Malinen E (2019)
    Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer
    Mol Imaging Biol, 21 (2), 391-398
    DOI 10.1007/s11307-018-1226-7, PubMed 29916117
  162. Shoemaker CJ, Huang TQ, Weir NR, Polyakov NJ, Schultz SW, Denic V (2019)
    CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
    PLoS Biol, 17 (4), e2007044
    DOI 10.1371/journal.pbio.2007044, PubMed 30933966
  163. Sioud M (2019)
    Phage Display Libraries: From Binders to Targeted Drug Delivery and Human Therapeutics
    Mol Biotechnol, 61 (4), 286-303
    DOI 10.1007/s12033-019-00156-8, PubMed 30729435
  164. Braadland PR, Urbanucci A (2019)
    Chromatin reprogramming as an adaptation mechanism in advanced prostate cancer
    Endocr Relat Cancer, 26 (4), R211-R235
    DOI 10.1530/ERC-18-0579, PubMed 30844748
  165. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
    Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
    Cold Spring Harb Mol Case Stud, 5 (2)
    DOI 10.1101/mcs.a003566, PubMed 30862609
  166. Hauge S, Macurek L, Syljuåsen RG (2019)
    p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775
    Cell Cycle, 18 (8), 834-847
    DOI 10.1080/15384101.2019.1593649, PubMed 30943845
  167. Thorsen T, Solheim JM, Labori KJ, Line PD, Aandahl EM (2019)
    Liver transplantation as a lifesaving procedure for posthepatectomy liver failure and iatrogenic liver injuries
    Langenbecks Arch Surg, 404 (3), 301-308
    DOI 10.1007/s00423-019-01780-3, PubMed 30929063
  168. Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
    The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
    J Biol Chem, 294 (20), 8197-8217
    DOI 10.1074/jbc.RA118.002829, PubMed 30926605
  169. Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, Johansen T (2019)
    The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS
    Front Genet, 10, 249
    DOI 10.3389/fgene.2019.00249, PubMed 30984240
  170. Crosbie EJ, Ryan NAJ, Arends MJ, Bosse T, Burn J, Cornes JM, Crawford R, Eccles D, Frayling IM, Ghaem-Maghami S, Hampel H, Kauff ND, Kitchener HC, Kitson SJ, Manchanda R, McMahon RFT, Monahan KJ, Menon U, Møller P, Möslein G, Rosenthal A, Sasieni P, Seif MW, Singh N, Skarrott P et al. (2019)
    The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome
    Genet Med, 21 (10), 2390-2400
    DOI 10.1038/s41436-019-0489-y, PubMed 30918358
  171. Cremaschi A, Argiento R, Shoemaker K, Peterson C, Vannucci M (2019)
    Hierarchical Normalized Completely Random Measures for Robust Graphical Modeling
    Bayesian Anal, 14 (4), 1271-1301
    DOI 10.1214/19-ba1153, PubMed 32431780
  172. Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T (2019)
    Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
    Clin Exp Immunol, 197 (1), 74-82
    DOI 10.1111/cei.13283, PubMed 30821848
  173. Switlyk MD, Salberg UB, Geier OM, Vlatkovic L, Lilleby W, Lyng H, Seierstad T (2019)
    PTEN Expression in Prostate Cancer: Relationship With Clinicopathologic Features and Multiparametric MRI Findings
    AJR Am J Roentgenol, 212 (6), 1206-1214
    DOI 10.2214/AJR.18.20743, PubMed 30888866
  174. Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H (2019)
    The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
    PLoS Pathog, 15 (3), e1007684
    DOI 10.1371/journal.ppat.1007684, PubMed 30883606
  175. Taylor-King JP, Baratchart E, Dhawan A, Coker EA, Rye IH, Russnes H, Chapman SJ, Basanta D, Marusyk A (2019)
    Simulated ablation for detection of cells impacting paracrine signalling in histology analysis
    Math Med Biol, 36 (1), 93-112
    DOI 10.1093/imammb/dqx022, PubMed 29452382
  176. Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, Schuetz C, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C, Reiff A, Ferguson PJ, Aghamohammadi A, Abolhassani H, Puck JM, Adeli M, Cancrini C, Palma P, Bertaina A, Locatelli F, Di Matteo G, Geha RS et al. (2019)
    Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency
    J Allergy Clin Immunol Pract, 7 (6), 1970-1985.e4
    DOI 10.1016/j.jaip.2019.02.038, PubMed 30877075
  177. GBD 2016 Stroke Collaborators (2019)
    Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
    Lancet Neurol, 18 (5), 439-458
    DOI 10.1016/S1474-4422(19)30034-1, PubMed 30871944
  178. Hauge A, Gaustad JV, Huang R, Simonsen TG, Wegner CS, Andersen LMK, Rofstad EK (2019)
    DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma
    Int J Radiat Oncol Biol Phys, 104 (3), 666-676
    DOI 10.1016/j.ijrobp.2019.03.002, PubMed 30858145
  179. Jonsson M, Fjeldbo CS, Holm R, Stokke T, Kristensen GB, Lyng H (2019)
    Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer
    Neoplasia, 21 (4), 353-362
    DOI 10.1016/j.neo.2019.01.002, PubMed 30856376
  180. Steen CB, Leich E, Myklebust JH, Lockmer S, Wise JF, Wahlin BE, Østenstad B, Liestøl K, Kimby E, Rosenwald A, Smeland EB, Holte H, Lingjærde OC, Brodtkorb M (2019)
    A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy
    Haematologica, 104 (10), e460-e464
    DOI 10.3324/haematol.2018.209080, PubMed 30846496
  181. Nunes-Xavier CE, Zaldumbide L, Aurtenetxe O, López-Almaraz R, López JI, Pulido R (2019)
    Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
    Int J Mol Sci, 20 (5)
    DOI 10.3390/ijms20051170, PubMed 30866462
  182. Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM (2019)
    Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response
    Cytometry A, 95 (4), 442-449
    DOI 10.1002/cyto.a.23737, PubMed 30838773
  183. Ten Broeke SW, Rodríguez-Girondo M, Suerink M, Aretz S, Bernstein I, Capellá G, Engel C, Gomez-Garcia EB, van Hest LP, von Knebel Doeberitz M, Lagerstedt-Robinson K, Letteboer TGW, Moller P, van Os TA, Pineda M, Rahner N, Olderode-Berends MJW, von Salomé J, Schackert HK, Spruijt L, Steinke-Lange V, Wagner A, Tops CMJ, Nielsen M (2019)
    The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect
    Cancer Epidemiol Biomarkers Prev, 28 (6), 1010-1014
    DOI 10.1158/1055-9965.EPI-18-0576, PubMed 30824524
  184. Kumar S, Gu Y, Abudu YP, Bruun JA, Jain A, Farzam F, Mudd M, Anonsen JH, Rusten TE, Kasof G, Ktistakis N, Lidke KA, Johansen T, Deretic V (2019)
    Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation
    Dev Cell, 49 (1), 130-144.e6
    DOI 10.1016/j.devcel.2019.01.027, PubMed 30827897
  185. Landsverk HB, Sandquist LE, Sridhara SC, Rødland GE, Sabino JC, de Almeida SF, Grallert B, Trinkle-Mulcahy L, Syljuåsen RG (2019)
    Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
    Nucleic Acids Res, 47 (4), 1797-1813
    DOI 10.1093/nar/gky1233, PubMed 30541148
  186. Gheorghe M, Sandve GK, Khan A, Chèneby J, Ballester B, Mathelier A (2019)
    A map of direct TF-DNA interactions in the human genome
    Nucleic Acids Res, 47 (4), e21
    DOI 10.1093/nar/gky1210, PubMed 30517703
  187. Seppälä TT, Ahadova A, Dominguez-Valentin M, Macrae F, Evans DG, Therkildsen C, Sampson J, Scott R, Burn J, Möslein G, Bernstein I, Holinski-Feder E, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lautrup CK, Lindblom A, Plazzer JP, Winship I, Tjandra D, Katz LH, Aretz S, Hüneburg R, Holzapfel S, Heinimann K et al. (2019)
    Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 8
    DOI 10.1186/s13053-019-0106-8, PubMed 30858900
  188. Aasen T, Leithe E, Graham SV, Kameritsch P, Mayán MD, Mesnil M, Pogoda K, Tabernero A (2019)
    Connexins in cancer: bridging the gap to the clinic
    Oncogene, 38 (23), 4429-4451
    DOI 10.1038/s41388-019-0741-6, PubMed 30814684
  189. Lund KV, Simonsen TG, Kristensen GB, Rofstad EK (2019)
    Pharmacokinetic analysis of DCE-MRI data of locally advanced cervical carcinoma with the Brix model
    Acta Oncol, 58 (6), 828-837
    DOI 10.1080/0284186X.2019.1580386, PubMed 30810443
  190. Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
    Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
    Cancer Immunol Res, 7 (5), 701-706
    DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006
  191. Escala-Garcia M, Guo Q, Dörk T, Canisius S, Keeman R, Dennis J, Beesley J, Lecarpentier J, Bolla MK, Wang Q, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Boeckx B, Bojesen SE, Bonanni B, Børresen-Dale AL et al. (2019)
    Genome-wide association study of germline variants and breast cancer-specific mortality
    Br J Cancer, 120 (6), 647-657
    DOI 10.1038/s41416-019-0393-x, PubMed 30787463
  192. Hanes R, Munthe E, Grad I, Han J, Karlsen I, McCormack E, Meza-Zepeda LA, Stratford EW, Myklebost O (2019)
    Preclinical Evaluation of the Pan-FGFR Inhibitor LY2874455 in FRS2-Amplified Liposarcoma
    Cells, 8 (2)
    DOI 10.3390/cells8020189, PubMed 30795553
  193. Berge LAM, Andreassen BK, Stenehjem JS, Larsen IK, Furu K, Juzeniene A, Roscher I, Heir T, Green A, Veierød MB, Robsahm TE (2019)
    Cardiovascular, antidepressant and immunosuppressive drug use in relation to risk of cutaneous melanoma: a protocol for a prospective case-control study
    BMJ Open, 9 (2), e025246
    DOI 10.1136/bmjopen-2018-025246, PubMed 30787091
  194. Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
    Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
    Nanotoxicology, 13 (6), 761-782
    DOI 10.1080/17435390.2019.1576238, PubMed 30760074
  195. Hansen EP, Fromm B, Andersen SD, Marcilla A, Andersen KL, Borup A, Williams AR, Jex AR, Gasser RB, Young ND, Hall RS, Stensballe A, Ovchinnikov V, Yan Y, Fredholm M, Thamsborg SM, Nejsum P (2019)
    Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk
    J Extracell Vesicles, 8 (1), 1578116
    DOI 10.1080/20013078.2019.1578116, PubMed 30815237
  196. Kotsopoulos J, Lubinski J, Lynch HT, Tung N, Armel S, Senter L, Singer CF, Fruscio R, Couch F, Weitzel JN, Karlan B, Foulkes WD, Moller P, Eisen A, Ainsworth P, Neuhausen SL, Olopade O, Sun P, Gronwald J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 175 (2), 443-449
    DOI 10.1007/s10549-019-05162-7, PubMed 30756284
  197. Røsok BI, Høst-Brunsell T, Brudvik KW, Carling U, Dorenberg E, Björnsson B, Lothe RA, Bjørnbeth BA, Sandström P (2019)
    Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
    HPB (Oxford), 21 (8), 1017-1023
    DOI 10.1016/j.hpb.2018.12.003, PubMed 30765198
  198. Sioud M (2019)
    Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy
    Cancers (Basel), 11 (2)
    DOI 10.3390/cancers11020176, PubMed 30717461
  199. Stankovic B, Bjørhovde HAK, Skarshaug R, Aamodt H, Frafjord A, Müller E, Hammarström C, Beraki K, Bækkevold ES, Woldbæk PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2019)
    Immune Cell Composition in Human Non-small Cell Lung Cancer
    Front Immunol, 9, 3101
    DOI 10.3389/fimmu.2018.03101, PubMed 30774636
  200. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
    Remodeling of secretory lysosomes during education tunes functional potential in NK cells
    Nat Commun, 10 (1), 514
    DOI 10.1038/s41467-019-08384-x, PubMed 30705279
  201. Zhang R, Lai L, He J, Chen C, You D, Duan W, Dong X, Zhu Y, Lin L, Shen S, Guo Y, Su L, Shafer A, Moran S, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC (2019)
    EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC
    Epigenetics, 14 (2), 118-129
    DOI 10.1080/15592294.2019.1573066, PubMed 30665327
  202. Shao B, Bjaanæs MM, Helland Å, Schütte C, Conrad T (2019)
    EMT network-based feature selection improves prognosis prediction in lung adenocarcinoma
    PLoS One, 14 (1), e0204186
    DOI 10.1371/journal.pone.0204186, PubMed 30703089
  203. Kryeziu K, Bruun J, Guren TK, Sveen A, Lothe RA (2019)
    Combination therapies with HSP90 inhibitors against colorectal cancer
    Biochim Biophys Acta Rev Cancer, 1871 (2), 240-247
    DOI 10.1016/j.bbcan.2019.01.002, PubMed 30708039
  204. Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S (2019)
    FOXK1 and FOXK2 regulate aerobic glycolysis
    Nature, 566 (7743), 279-283
    DOI 10.1038/s41586-019-0900-5, PubMed 30700909
  205. Cheng J, Demeulemeester J, Wedge DC, Vollan HKM, Pitt JJ, Russnes HG, Pandey BP, Nilsen G, Nord S, Bignell GR, White KP, Børresen-Dale AL, Campbell PJ, Kristensen VN, Stratton MR, Lingjærde OC, Moreau Y, Van Loo P (2019)
    Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
    Nat Commun, 10 (1), 525
    DOI 10.1038/s41467-019-08512-7, PubMed 30692535
  206. Smid M, Wilting SM, Uhr K, Rodríguez-González FG, de Weerd V, Prager-Van der Smissen WJC, van der Vlugt-Daane M, van Galen A, Nik-Zainal S, Butler A, Martin S, Davies HR, Staaf J, van de Vijver MJ, Richardson AL, MacGrogan G, Salgado R, van den Eynden GGGM, Purdie CA, Thompson AM, Caldas C, Span PN, Sweep FCGJ, Simpson PT, Lakhani SR et al. (2019)
    The circular RNome of primary breast cancer
    Genome Res, 29 (3), 356-366
    DOI 10.1101/gr.238121.118, PubMed 30692147
  207. Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K (2019)
    The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
    J Immunol, 202 (5), 1397-1405
    DOI 10.4049/jimmunol.1701703, PubMed 30692213
  208. Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV et al. (2019)
    Shared heritability and functional enrichment across six solid cancers
    Nat Commun, 10 (1), 431
    DOI 10.1038/s41467-018-08054-4, PubMed 30683880
  209. Briem E, Ingthorsson S, Traustadottir GA, Hilmarsdottir B, Gudjonsson T (2019)
    Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D Culture
    J Mammary Gland Biol Neoplasia, 24 (2), 139-147
    DOI 10.1007/s10911-018-09424-w, PubMed 30684066
  210. Bowitz Lothe IM, Kleive D, Pomianowska E, Cvancarova M, Kure E, Dueland S, Gladhaug IP, Labori KJ (2019)
    Clinical relevance of pancreatobiliary and intestinal subtypes of ampullary and duodenal adenocarcinoma: Pattern of recurrence, chemotherapy, and survival after pancreatoduodenectomy
    Pancreatology, 19 (2), 316-324
    DOI 10.1016/j.pan.2019.01.019, PubMed 30713128
  211. Lee YS, Krishnan A, Oughtred R, Rust J, Chang CS, Ryu J, Kristensen VN, Dolinski K, Theesfeld CL, Troyanskaya OG (2019)
    A Computational Framework for Genome-wide Characterization of the Human Disease Landscape
    Cell Syst, 8 (2), 152-162.e6
    DOI 10.1016/j.cels.2018.12.010, PubMed 30685436
  212. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2019)
    Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift
    Cancers (Basel), 11 (2)
    DOI 10.3390/cancers11020132, PubMed 30678073
  213. Camilio KA, Wang MY, Mauseth B, Waagene S, Kvalheim G, Rekdal Ø, Sveinbjørnsson B, Mælandsmo GM (2019)
    Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
    Breast Cancer Res, 21 (1), 9
    DOI 10.1186/s13058-018-1092-x, PubMed 30670061
  214. Kyte JA, Fåne A, Pule M, Gaudernack G (2019)
    Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination
    Oncoimmunology, 8 (4), e1565236
    DOI 10.1080/2162402X.2019.1565236, PubMed 30906659
  215. Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fåne A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Wälchli S (2019)
    NK cells specifically TCR-dressed to kill cancer cells
    EBioMedicine, 40, 106-117
    DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853
  216. Josefsson SE, Beiske K, Blaker YN, Førsund MS, Holte H, Østenstad B, Kimby E, Köksal H, Wälchli S, Bai B, Smeland EB, Levy R, Kolstad A, Huse K, Myklebust JH (2019)
    TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma
    Cancer Immunol Res, 7 (3), 355-362
    DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053
  217. Nilsen A, Jonsson M, Aarnes EK, Kristensen GB, Lyng H (2019)
    Reference MicroRNAs for RT-qPCR Assays in Cervical Cancer Patients and Their Application to Studies of HPV16 and Hypoxia Biomarkers
    Transl Oncol, 12 (3), 576-584
    DOI 10.1016/j.tranon.2018.12.010, PubMed 30660934
  218. Nunes-Xavier CE, Angulo JC, Pulido R, López JI (2019)
    A Critical Insight into the Clinical Translation of PD-1/PD-L1 Blockade Therapy in Clear Cell Renal Cell Carcinoma
    Curr Urol Rep, 20 (1), 1
    DOI 10.1007/s11934-019-0866-8, PubMed 30645700
  219. Eide PW, Eilertsen IA, Sveen A, Lothe RA (2019)
    Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell-intrinsic properties
    Int J Cancer, 144 (11), 2843-2853
    DOI 10.1002/ijc.31998, PubMed 30447009
  220. Mensali N, Grenov A, Pati NB, Dillard P, Myhre MR, Gaudernack G, Kvalheim G, Inderberg EM, Bakke O, Wälchli S (2019)
    Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
    Oncoimmunology, 8 (3), 1558663
    DOI 10.1080/2162402X.2018.1558663, PubMed 30723591
  221. Woldemariam NT, Agafonov O, Høyheim B, Houston RD, Taggart JB, Andreassen R (2019)
    Expanding the miRNA Repertoire in Atlantic Salmon; Discovery of IsomiRs and miRNAs Highly Expressed in Different Tissues and Developmental Stages
    Cells, 8 (1)
    DOI 10.3390/cells8010042, PubMed 30641951
  222. Kraby MR, Opdahl S, Russnes HG, Bofin AM (2019)
    Microvessel density in breast cancer: the impact of field area on prognostic informativeness
    J Clin Pathol, 72 (4), 304-310
    DOI 10.1136/jclinpath-2018-205536, PubMed 30630872
  223. Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P et al. (2019)
    EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
    SLAS Discov, 24 (3), 398-413
    DOI 10.1177/2472555218816276, PubMed 30616481
  224. Bergholtz H, Lien TG, Ursin G, Holmen MM, Helland Å, Sørlie T, Haakensen VD (2019)
    A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
    J Mammary Gland Biol Neoplasia, 24 (2), 163-175
    DOI 10.1007/s10911-018-09423-x, PubMed 30613869
  225. Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S (2019)
    The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy
    Mol Cell, 73 (3), 429-445.e7
    DOI 10.1016/j.molcel.2018.11.018, PubMed 30612879
  226. Silva A, Bassim S, Sarkozy C, Mottok A, Lackraj T, Jurinovic V, Brodtkorb M, Lingjaerde OC, Sehn LH, Gascoyne RD, Weigert O, Steidl C, Kridel R (2019)
    Convergence of risk prediction models in follicular lymphoma
    Haematologica, 104 (6), e252-e255
    DOI 10.3324/haematol.2018.209031, PubMed 30606786
  227. Khezri R, Rusten TE (2019)
    Autophagy and Tumorigenesis in Drosophila
    Adv Exp Med Biol, 1167, 113-127
    DOI 10.1007/978-3-030-23629-8_7, PubMed 31520352
  228. Khezri R, Rusten TE (2019)
    Correction to: Autophagy and Tumorigenesis in Drosophila
    Adv Exp Med Biol, 1167, C1
    DOI 10.1007/978-3-030-23629-8_15, PubMed 33306185
  229. Pielke R, Boye E (2019)
    Scientific integrity and anti-doping regulation
    Int. J. Sport Policy Polit., 11 (2), 295-313
    DOI 10.1080/19406940.2019.1596968
  230. Lindholm EM, Leivonen SK, Undlien E, Nebdal D, Git A, Caldas C, Børresen-Dale AL, Kleivi K (2019)
    miR-342-5p as a Potential Regulator of HER2 Breast Cancer Cell Growth
    Microrna, 8 (2), 155-165
    DOI 10.2174/2211536608666181206124922, PubMed 30520388
  231. Ney A, Mahamed I, Garcia-Sampedro A, Selbo PK, Sancho P, MacRobert AJ, Pereira SP, Acedo P (2019)
    Combination light-based therapies to treat pancreatic cancer: a proof of concept
    PROC SPIE, 11070, UNSP 1107045
    DOI 10.1117/12.2525305
  232. Sun CH, Berg K, Hirschberg H (2019)
    Photochemical Internalization Enhanced Nonviral Suicide Gene Therapy
    Methods Mol Biol, 1895, 165-176