Publications

Publications published since 2018 from OUS - Institute for Cancer Research

1182 publications found (only first 1000 shown)

Publications 2023

  1. Leivonen SK, Friman T, Autio M, Vaittinen S, Jensen AW, D'Amore F, Hamilton-Dutoit SJ, Holte H, Beiske K, Kovanen PE, Räty R, Leppä S (2023)
    Characterization and clinical impact of the tumor microenvironment in post-transplant aggressive B-cell lymphomas
    Haematologica (in press)
    DOI 10.3324/haematol.2023.282831, PubMed 37259566
  2. Dyrbekk APH, Warsame AA, Suhrke P, Ludahl MO, Moe JO, Eide IJZ, Lund-Iversen M, Brustugun OT (2023)
    "Evaluation of ROS1 expression and rearrangements in a large cohort of early-stage lung cancer"
    Diagn Pathol, 18 (1), 70
    DOI 10.1186/s13000-023-01357-1, PubMed 37237384
  3. Potdar S, Ianevski F, Ianevski A, Tanoli Z, Wennerberg K, Seashore-Ludlow B, Kallioniemi O, Östling P, Aittokallio T, Saarela J (2023)
    Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data
    Nucleic Acids Res (in press)
    DOI 10.1093/nar/gkad390, PubMed 37178002
  4. Wu Y, Wang Z, Zhao Z, Song X, Miao M, Zhang X (2023)
    Bile acid metabolites in early pregnancy and risk of gestational diabetes mellitus: Results from a prospective cohort study
    Diabetes Obes Metab (in press)
    DOI 10.1111/dom.15104, PubMed 37161712
  5. Zhen Y, Stenmark H (2023)
    A phosphoinositide kinase triggers migrasome formation
    Cell Res (in press)
    DOI 10.1038/s41422-023-00822-2, PubMed 37165066
  6. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 7339
    DOI 10.1038/s41598-023-34087-x, PubMed 37147361
  7. Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE (2023)
    BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
    Circ Res, 132 (11), e188-e205
    DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790
  8. Sioud M (2023)
    How the initial discovery of modified RNA enabled evasion of innate immune responses and facilitated the development of RNA therapeutics
    Scand J Immunol, e13282 (in press)
    DOI 10.1111/sji.13282, PubMed 37132451
  9. Otte M, Stachelscheid J, Glaß M, Wahnschaffe L, Jiang Q, Lone W, Ianevski A, Aittokallio T, Iqbal J, Hallek M, Hüttelmaier S, Schrader A, Braun T, Herling M (2023)
    The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL
    Cancers (Basel), 15 (9)
    DOI 10.3390/cancers15092527, PubMed 37173993
  10. Bucher-Johannessen C, Birkeland EE, Vinberg E, Bemanian V, Hoff G, Berstad P, Rounge TB (2023)
    Long-term follow-up of colorectal cancer screening attendees identifies differences in Phascolarctobacterium spp. using 16S rRNA and metagenome sequencing
    Front Oncol, 13, 1183039
    DOI 10.3389/fonc.2023.1183039, PubMed 37182146
  11. Rim S, Sakkestad ST, Zhou F, Gullaksen SE, Skavland J, Chauhan SK, Steinsland H, Hanevik K (2023)
    Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection
    Eur J Immunol, e2250254 (in press)
    DOI 10.1002/eji.202250254, PubMed 37102399
  12. Rakaee M, Andersen S, Giannikou K, Paulsen EE, Kilvaer TK, Busund LR, Berg T, Richardsen E, Lombardi AP, Adib E, Pedersen MI, Tafavvoghi M, Wahl SGF, Petersen RH, Bondgaard AL, Yde CW, Baudet C, Licht P, Lund-Iversen M, Grønberg BH, Fjellbirkeland L, Helland Å, Pøhl M, Kwiatkowski DJ, Donnem T (2023)
    Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
    Ann Oncol (in press)
    DOI 10.1016/j.annonc.2023.04.005, PubMed 37100205
  13. Bay LTE, Stokke T, Syljuåsen RG, Landsverk HB (2023)
    Analysis of RNA Polymerase II Chromatin Binding by Flow Cytometry
    Bio Protoc, 13 (8), e4659
    DOI 10.21769/BioProtoc.4659, PubMed 37113330
  14. Zhang Q, Sioud M (2023)
    Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting
    Int J Mol Sci, 24 (8)
    DOI 10.3390/ijms24087493, PubMed 37108657
  15. Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, Sørensen Ø, Iyer A, Sengupta D, Prasmickaite L, Mælandsmo GM, Köhn-Luque A, Farhan H (2023)
    A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
    PLoS Comput Biol, 19 (4), e1010995
    DOI 10.1371/journal.pcbi.1010995, PubMed 37068117
  16. Hermansen JU, Yin Y, Urban A, Myklebust CV, Karlsen L, Melvold K, Tveita AA, Taskén K, Munthe LA, Tjønnfjord GE, Skånland SS (2023)
    A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
    Cell Death Discov, 9 (1), 125
    DOI 10.1038/s41420-023-01426-w, PubMed 37055391
  17. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 1767
    DOI 10.1038/s41467-023-37488-8, PubMed 36997540
  18. Zhang D, Harris HM, Chen J, Judy J, James G, Kelly A, McIntosh J, Tenn-McClellan A, Ambing E, Tan YS, Lu H, Gajewski S, Clifton MC, Yung S, Robbins DW, Pirooznia M, Skånland SS, Gaglione E, Mhibik M, Underbayev C, Ahn IE, Sun C, Herman SEM, Noviski M, Wiestner A (2023)
    NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts
    Blood, 141 (13), 1584-1596
    DOI 10.1182/blood.2022016934, PubMed 36375120
  19. Sioud M, Zhang Q (2023)
    Precision Killing of M2 Macrophages with Phage-Displayed Peptide-Photosensitizer Conjugates
    Cancers (Basel), 15 (7)
    DOI 10.3390/cancers15072009, PubMed 37046671
  20. Haroun-Izquierdo A, Lanuza PM, Pfefferle A, Netskar H, Ask EH, Törlén J, Björklund A, Sohlberg E, Malmberg KJ (2023)
    Effect of mTOR Inhibition with Sirolimus on Natural Killer Cell Reconstitution in Allogeneic Stem Cell Transplantation
    Transplant Cell Ther (in press)
    DOI 10.1016/j.jtct.2023.03.023, PubMed 36966873
  21. Sioud M, Olberg A (2023)
    Antibody Surface Profiling Identifies Glycoforms in Multiple Myeloma as Targets for Immunotherapy: From Antibody Derivatives to Mimetic Peptides for Killing Tumor Cells
    Cancers (Basel), 15 (7)
    DOI 10.3390/cancers15071934, PubMed 37046595
  22. Schiavi A, Salveridou E, Brinkmann V, Shaik A, Menzel R, Kalyanasundaram S, Nygård S, Nilsen H, Ventura N (2023)
    Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
    iScience, 26 (4), 106448
    DOI 10.1016/j.isci.2023.106448, PubMed 37020951
  23. Patrick-Brown TDJH, Mohamed F, Thrower A, Torgunrud A, Cosyns S, Canbay E, Villeneuve L, Flatmark K, Brandl A (2023)
    Determining a minimum data set for reporting clinical and radiologic data for pseudomyxoma peritonei
    Pleura Peritoneum, 8 (1), 1-9
    DOI 10.1515/pp-2022-0200, PubMed 37020469
  24. Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
    Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
    EClinicalMedicine, 58, 101909
    DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
  25. Ito I, Yousef AM, Dickson PN, Naini ZA, White MG, Fleten KG, Flatmark K, Fournier KF, Fowlkes NW, Shen JP (2023)
    Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
    bioRxiv
    DOI 10.1101/2023.02.01.526672, PubMed 36993681
  26. Arjona-Sanchez A, Martinez-López A, Moreno-Montilla MT, Mulsow J, Lozano-Lominchar P, Martínez-Torres B, Rau B, Canbay E, Sommariva A, Milione M, Deraco M, Sgarbura O, Torgunrud A, Kepenekian V, Carr NJ, Hoorens A, Delhorme JB, Wernert R, Goere D, Martin-Roman L, Cosyns S, Flatmark K, Davidson B, Khellaf L, Pereira-Perez F et al. (2023)
    External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification
    Eur J Surg Oncol (in press)
    DOI 10.1016/j.ejso.2023.03.206, PubMed 36935222
  27. Humbert M, Olofsson A, Wullimann D, Niessl J, Hodcroft EB, Cai C, Gao Y, Sohlberg E, Dyrdak R, Mikaeloff F, Neogi U, Albert J, Malmberg KJ, Lund-Johansen F, Aleman S, Björkhem-Bergman L, Jenmalm MC, Ljunggren HG, Buggert M, Karlsson AC (2023)
    Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
    Proc Natl Acad Sci U S A, 120 (12), e2220320120
    DOI 10.1073/pnas.2220320120, PubMed 36917669
  28. Halkola AS, Joki K, Mirtti T, Mäkelä MM, Aittokallio T, Laajala TD (2023)
    OSCAR: Optimal subset cardinality regression using the L0-pseudonorm with applications to prognostic modelling of prostate cancer
    PLoS Comput Biol, 19 (3), e1010333
    DOI 10.1371/journal.pcbi.1010333, PubMed 36897911
  29. Chauhan SK, Casado RB, Landsverk OJB, Johannessen H, Phung D, Nilsen HR, Sætre F, Jahnsen J, Horneland R, Yaqub S, Aandahl EM, Lundin KEA, Bækkevold ES, Jahnsen FL (2023)
    The human small intestine contains two functionally distinct regulatory T-cell subsets
    J Allergy Clin Immunol (in press)
    DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861
  30. Bruland ØS, Larsen RH, Baum RP, Juzeniene A (2023)
    Editorial: Targeted alpha particle therapy in oncology
    Front Med (Lausanne), 10, 1165747
    DOI 10.3389/fmed.2023.1165747, PubMed 36960341
  31. Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
    Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
    Cell Commun Signal, 21 (1), 50
    DOI 10.1186/s12964-023-01062-y, PubMed 36882786
  32. Vahid MR, Brown EL, Steen CB, Zhang W, Jeon HS, Kang M, Gentles AJ, Newman AM (2023)
    High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE
    Nat Biotechnol (in press)
    DOI 10.1038/s41587-023-01697-9, PubMed 36879008
  33. Köhn-Luque A, Myklebust EM, Tadele DS, Giliberto M, Schmiester L, Noory J, Harivel E, Arsenteva P, Mumenthaler SM, Schjesvold F, Taskén K, Enserink JM, Leder K, Frigessi A, Foo J (2023)
    Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
    Cell Rep Methods, 3 (3), 100417
    DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380
  34. Skogestad J, Albert I, Hougen K, Lothe GB, Lunde M, Eken OS, Veras I, Huynh NTT, Børstad M, Marshall S, Shen X, Louch WE, Robinson EL, Cleveland JC, Ambardekar AV, Schwisow JA, Jonas E, Calejo AI, Morth JP, Taskén K, Melleby AO, Lunde PK, Sjaastad I, Carlson CR, Aronsen JM (2023)
    Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
    Circulation, 147 (16), 1221-1236
    DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489
  35. Isaksen KT, Galleberg R, Mastroianni MA, Rinde M, Rusten LS, Barzenje D, Ramslien F, Fluge O, Slaaen M, Meyer P, Liestol K, Smeland EB, Lingjarde OC, Holte H, Brodtkorb M (2023)
    The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
    Haematologica (in press)
    DOI 10.3324/haematol.2022.282289, PubMed 36861406
  36. Getu AA, Tigabu A, Zhou M, Lu J, Fodstad Ø, Tan M (2023)
    New frontiers in immune checkpoint B7-H3 (CD276) research and drug development
    Mol Cancer, 22 (1), 43
    DOI 10.1186/s12943-023-01751-9, PubMed 36859240
  37. van Royen ME, Soekmadji C, Grange C, Webber JP, Tertel T, Droste M, Buescher A, Giebel B, Jenster GW, Llorente A, Blijdorp CJ, Burger D, Erdbrügger U, Martens-Uzunova ES (2023)
    The quick reference card "Storage of urinary EVs" - A practical guideline tool for research and clinical laboratories
    J Extracell Vesicles, 12 (3), e12286
    DOI 10.1002/jev2.12286, PubMed 36916183
  38. Xia NH, Xie CF, Liu YS, Wei B, Zhang HL, Guo Z, Zhang L, Wang MY, He XD (2023)
    Two-dimensional displacement estimation of one-dimensional laser speckle images for detection of acoustic vibration
    Appl Opt, 62 (7), 1785-1790
    DOI 10.1364/AO.482438, PubMed 37132926
  39. Severson TM, Zhu Y, Prekovic S, Schuurman K, Nguyen HM, Brown LG, Hakkola S, Kim Y, Kneppers J, Linder S, Stelloo S, Lieftink C, van der Heijden M, Nykter M, van der Noort V, Sanders J, Morris B, Jenster G, van Leenders GJ, Pomerantz M, Freedman ML, Beijersbergen RL, Urbanucci A, Wessels L, Corey E et al. (2023)
    Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients
    medRxiv
    DOI 10.1101/2023.02.24.23286403, PubMed 36865297
  40. Pettersen S, Øy GF, Egeland EV, Juell S, Engebråten O, Mælandsmo GM, Prasmickaite L (2023)
    Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
    Front Oncol, 13, 1040665
    DOI 10.3389/fonc.2023.1040665, PubMed 36910663
  41. Zhen Y, Stenmark H (2023)
    Autophagosome Biogenesis
    Cells, 12 (4)
    DOI 10.3390/cells12040668, PubMed 36831335
  42. Lorenzovici L, Szilberhorn L, Farkas-Ráduly S, Gasparik AI, Precup AM, Nagy AG, Niemann CU, Aittokallio T, Kaló Z, Csanádi M (2023)
    Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia
    BioDrugs, 37 (2), 219-233
    DOI 10.1007/s40259-023-00583-9, PubMed 36795353
  43. Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K (2023)
    A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
    Cancer Res Commun, 3 (2), 235-244
    DOI 10.1158/2767-9764.CRC-22-0295, PubMed 36968142
  44. van den Berg CM, Volkov VA, Schnorrenberg S, Huang Z, Stecker KE, Grigoriev I, Gilani S, Frikstad KM, Patzke S, Zimmermann T, Dogterom M, Akhmanova A (2023)
    CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
    J Cell Biol, 222 (4)
    DOI 10.1083/jcb.202208062, PubMed 36752787
  45. Attard G, Parry M, Grist E, Mendes L, Dutey-Magni P, Sachdeva A, Brawley C, Murphy L, Proudfoot J, Lall S, Liu Y, Friedrich S, Ismail M, Hoyle A, Ali A, Haran A, Wingate A, Zakka L, Wetterskog D, Amos C, Atako N, Wang V, Rush H, Jones R, Leung H et al. (2023)
    Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
    Res Sq
    DOI 10.21203/rs.3.rs-2488586/v1, PubMed 36798177
  46. Beck C, Casey NP, Persiconi I, Moharrami NN, Sike A, Jin Y, Kyte JA (2023)
    Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
    Biomedicines, 11 (2)
    DOI 10.3390/biomedicines11020459, PubMed 36830995
  47. Bajo-Santos C, Brokāne A, Zayakin P, Endzeliņš E, Soboļevska K, Belovs A, Jansons J, Sperga M, Llorente A, Radoviča-Spalviņa I, Lietuvietis V, Linē A (2023)
    Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
    Front Mol Biosci, 10, 980433
    DOI 10.3389/fmolb.2023.980433, PubMed 36818049
  48. Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
    Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
    Proc Natl Acad Sci U S A, 120 (6), e2211368120
    DOI 10.1073/pnas.2211368120, PubMed 36730202
  49. Meier Strømme J, Johannessen B, Skotheim RI (2023)
    Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer
    JCO Clin Cancer Inform, 7, e2200159
    DOI 10.1200/CCI.22.00159, PubMed 36821799
  50. Odabasi E, Conkar D, Deretic J, Batman U, Frikstad KM, Patzke S, Firat-Karalar EN (2023)
    CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins
    J Cell Sci, 136 (3)
    DOI 10.1242/jcs.260327, PubMed 36606424
  51. Sagini K, Urbanelli L, Buratta S, Emiliani C, Llorente A (2023)
    Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
    Pharmaceutics, 15 (2)
    DOI 10.3390/pharmaceutics15020437, PubMed 36839759
  52. Nunzi E, Mezzasoma L, Bellezza I, Zelante T, Orvietani P, Coata G, Giardina I, Sagini K, Manni G, Di Michele A, Gargaro M, Talesa VN, Di Renzo GC, Fallarino F, Romani R (2023)
    Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
    Int J Mol Sci, 24 (3)
    DOI 10.3390/ijms24032527, PubMed 36768851
  53. Normann LS, Haugen MH, Hongisto V, Aure MR, Leivonen SK, Kristensen VN, Tahiri A, Engebraaten O, Sahlberg KK, Mælandsmo GM (2023)
    High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
    PLoS One, 18 (1), e0280507
    DOI 10.1371/journal.pone.0280507, PubMed 36706086
  54. Doutel D, Davidson B, Nitschke Pettersen IK, Torgunrud A (2023)
    Molecular characteristics of low-grade serous carcinoma in effusions
    Cytopathology, 34 (2), 99-105
    DOI 10.1111/cyt.13207, PubMed 36609991
  55. Daniel P, Balušíková K, Václavíková R, Šeborová K, Ransdorfová Š, Valeriánová M, Wei L, Jelínek M, Tlapáková T, Fleischer T, Kristensen VN, Souček P, Ojima I, Kovář J (2023)
    ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines
    Genes (Basel), 14 (2)
    DOI 10.3390/genes14020296, PubMed 36833223
  56. Vitelli V, Fleischer T, Ankill J, Arjas E, Frigessi A, Kristensen VN, Zucknick M (2023)
    Transcriptomic pan-cancer analysis using rank-based Bayesian inference
    Mol Oncol, 17 (4), 548-563
    DOI 10.1002/1878-0261.13354, PubMed 36562628
  57. Skoie IM, Skogås JG, Langø T, Myhr KM, Myhre PL, Goll R, Fretland SØ, Helland Å (2023)
    New centres to carry out more clinical trials in Norway
    Tidsskr Nor Laegeforen, 143 (2)
    DOI 10.4045/tidsskr.22.0722, PubMed 36718905
  58. Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, Chandrasekar C, Schiffman JD, Brohl AS, James PA, Kurtz JE, Penel N, Myklebost O, Meza-Zepeda LA, Pickett H, Kansara M et al. (2023)
    Heritable defects in telomere and mitotic function selectively predispose to sarcomas
    Science, 379 (6629), 253-260
    DOI 10.1126/science.abj4784, PubMed 36656928
  59. Ramos-Alonso L, Holland P, Le Gras S, Zhao X, Jost B, Bjørås M, Barral Y, Enserink JM, Chymkowitch P (2023)
    Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
    Proc Natl Acad Sci U S A, 120 (4), e2210593120
    DOI 10.1073/pnas.2210593120, PubMed 36656860
  60. Juzeniene A, Stenberg VY, Bruland ØS, Revheim ME, Larsen RH (2023)
    Dual targeting with 224Ra/212Pb-conjugates for targeted alpha therapy of disseminated cancers: A conceptual approach
    Front Med (Lausanne), 9, 1051825
    DOI 10.3389/fmed.2022.1051825, PubMed 36733936
  61. Johanssen T, McVeigh L, Erridge S, Higgins G, Straehla J, Frame M, Aittokallio T, Carragher NO, Ebner D (2023)
    Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia
    Front Oncol, 12, 1075559
    DOI 10.3389/fonc.2022.1075559, PubMed 36733367
  62. Ellingsen EB, Bjørheim J, Gaudernack G (2023)
    Therapeutic cancer vaccination against telomerase: clinical developments in melanoma
    Curr Opin Oncol, 35 (2), 100-106
    DOI 10.1097/CCO.0000000000000922, PubMed 36700456
  63. Hyldbakk A, Fleten KG, Snipstad S, Åslund AKO, Davies CL, Flatmark K, Mørch Y (2023)
    Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
    Nanomedicine, 48, 102656
    DOI 10.1016/j.nano.2023.102656, PubMed 36646195
  64. Panagiotakis S, Mavroidi B, Athanasopoulos A, Gonçalves AR, Bugnicourt-Moreira L, Regagnon T, Boukos N, Charalambidis G, Coutsolelos AG, Grigalavicius M, Theodossiou TA, Berg K, Ladavière C, Pelecanou M, Yannakopoulou K (2023)
    Small anticancer drug release by light: Photochemical internalization of porphyrin-β-cyclodextrin nanoparticles
    Carbohydr Polym, 306, 120579
    DOI 10.1016/j.carbpol.2023.120579, PubMed 36746578
  65. Shah UA, Whiting K, Devlin S, Ershler R, Kanapuru B, Lee DJ, Tahri S, Gwise T, Rustad EH, Mailankody S, Lesokhin AM, Kazandjian D, Maura F, Auclair D, Birmann BM, Usmani SZ, Gormley N, Marinac CR, Landgren O (2023)
    Extreme body mass index and survival in newly diagnosed multiple myeloma patients
    Blood Cancer J, 13 (1), 13
    DOI 10.1038/s41408-022-00782-7, PubMed 36631444
  66. Kamijo K, Shimomura Y, Shinohara A, Mizuno S, Kanaya M, Usui Y, Kim SW, Ara T, Mizuno I, Kuriyama T, Nakazawa H, Matsuoka KI, Kusumoto S, Maseki N, Yamaguchi M, Ashida T, Onizuka M, Fukuda T, Atsuta Y, Kondo E (2023)
    Fludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation
    Ann Hematol, 102 (3), 651-661
    DOI 10.1007/s00277-023-05084-x, PubMed 36631705
  67. Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai KZ, Madssen TS, Vaage JT, Gustavsen A, Yang W, Nissen-Meyer LSH, Douvlataniotis K, Laos M, Nielsen MM, Thiede B, Søraas A, Lund-Johansen F, Rustad EH, Olweus J (2023)
    Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
    Cell Rep, 42 (1), 111995
    DOI 10.1016/j.celrep.2023.111995, PubMed 36656713
  68. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 115
    DOI 10.1038/s41467-022-35624-4, PubMed 36611026
  69. Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
    The genetic history of Scandinavia from the Roman Iron Age to the present
    Cell, 186 (1), 32-46.e19
    DOI 10.1016/j.cell.2022.11.024, PubMed 36608656
  70. Pulido R, Nunes-Xavier CE (2023)
    Editorial: Cell and Developmental Signalling in Neuroblastoma
    Front Cell Dev Biol, 10, 1126352
    DOI 10.3389/fcell.2022.1126352, PubMed 36684434
  71. Chojnacka M, Diamond B, Ziccheddu B, Rustad E, Maclachlan K, Papadimitriou M, Boyle EM, Blaney P, Usmani S, Morgan G, Landgren O, Maura F (2023)
    Impact of rare structural variant events in newly diagnosed multiple myeloma
    bioRxiv
    DOI 10.1101/2023.01.03.522573, PubMed 36711679
  72. Levy-Jurgenson A, Tekpli X, Kristensen VN, Yakhini Z (2023)
    Analysis of Spatial Molecular Data
    Methods Mol Biol, 2614, 349-356
    DOI 10.1007/978-1-0716-2914-7_20, PubMed 36587134
  73. Robsahm TE, Tsuruda KM, Hektoen HH, Storås AH, Cook MB, Hurwitz LM, Langseth H (2023)
    Applying recommended definition of aggressive prostate cancer: a validation study using high-quality data from the Cancer Registry of Norway
    Acta Oncol, 62 (1), 8-14
    DOI 10.1080/0284186X.2023.2175331, PubMed 36762472
  74. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
  75. Skånland SS, Brown JR (2023)
    PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
    Haematologica, 108 (1), 9-21
    DOI 10.3324/haematol.2022.281266, PubMed 35899388
  76. Leech M, Leijenaar RTH, Hompland T, Gaffney J, Lyng H, Marignol L (2023)
    Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring
    Anticancer Res, 43 (1), 351-357
    DOI 10.21873/anticanres.16170, PubMed 36585179
  77. Wind A, Oberst S, Westerhuis W, Blaauwgeers H, Sæter G, de Paoli P, Nagy P, Burrion JB, Jolly E, Lovey J, van Harten W (2023)
    Evaluating comprehensive cancer networks; a review of standards and evaluation methods for care networks to inform a comparison with the OECI comprehensive cancer network standards
    Acta Oncol, 62 (1), 15-24
    DOI 10.1080/0284186X.2023.2170275, PubMed 36786345
  78. Jeanmougin M, Brodal HP, Dietrichson Pharo H, Vedeld HM, Lind GE (2023)
    PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac766, PubMed 36448696

Publications 2022

  1. Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
    T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
    Gigascience, 12
    DOI 10.1093/gigascience/giad032, PubMed 37161965
  2. Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA (2022)
    The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
    Cancer, 129 (6), 901-907
    DOI 10.1002/cncr.34615, PubMed 36571512
  3. Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
    Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
    Front Cell Dev Biol, 10, 1022191
    DOI 10.3389/fcell.2022.1022191, PubMed 36619857
  4. Torices L, Mingo J, Rodríguez-Escudero I, Fernández-Acero T, Luna S, Nunes-Xavier CE, López JI, Mercadillo F, Currás M, Urioste M, Molina M, Cid VJ, Pulido R (2022)
    Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
    Eur J Hum Genet, 31 (5), 568-577
    DOI 10.1038/s41431-022-01265-w, PubMed 36543932
  5. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A et al. (2022)
    Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
    Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
    DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
  6. Vaccaro CA, Soarez J, Dominguez-Valentin M, Pavicic WH (2022)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
    Front Oncol, 12, 1104671
    DOI 10.3389/fonc.2022.1104671, PubMed 36601476
  7. Lyng H, Skipar K, Hompland T (2022)
    Targeted Therapy on the Screen: Do We Hit the Target?
    Clin Cancer Res, 28 (24), 5233-5234
    DOI 10.1158/1078-0432.CCR-22-2707, PubMed 36240006
  8. Kuźniewska A, Thiel M, Kowalska D, Felberg-Miętka A, Szynkowski P, Ołdziej S, Arjona E, Jongerius I, Rodriguez de Córdoba S, Okrój M, Urban A (2022)
    Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein
    Front Immunol, 13, 1061696
    DOI 10.3389/fimmu.2022.1061696, PubMed 36591303
  9. Sinno N, Taylor E, Hompland T, Milosevic M, Jaffray DA, Coolens C (2022)
    Incorporating cross-voxel exchange for the analysis of dynamic contrast-enhanced imaging data: pre-clinical results
    Phys Med Biol, 67 (24)
    DOI 10.1088/1361-6560/aca512, PubMed 36541560
  10. Gulati G, Tjessem KH, Horndalsveen H, Halvorsen S, Haakensen VD (2022)
    [Not Available]
    Tidsskr Nor Laegeforen, 142 (18)
    DOI 10.4045/tidsskr.21.0817, PubMed 36511752
  11. Charsou C, Ng MYW, Simonsen A (2022)
    Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
    Autophagy, 1-3 (in press)
    DOI 10.1080/15548627.2022.2155020, PubMed 36469687
  12. Hugosson J, Månsson M, Wallström J, Axcrona U, Carlsson SV, Egevad L, Geterud K, Khatami A, Kohestani K, Pihl CG, Socratous A, Stranne J, Godtman RA, Hellström M, GÖTEBORG-2 Trial Investigators (2022)
    Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only
    N Engl J Med, 387 (23), 2126-2137
    DOI 10.1056/NEJMoa2209454, PubMed 36477032
  13. Murumägi A, Ungureanu D, Khan S, Arjama M, Välimäki K, Ianevski A, Ianevski P, Bergström R, Dini A, Kanerva A, Koivisto-Korander R, Tapper J, Lassus H, Loukovaara M, Mägi A, Hirasawa A, Aoki D, Pietiäinen V, Pellinen T, Bützow R, Aittokallio T, Kallioniemi O (2022)
    Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma
    Br J Cancer, 128 (4), 678-690
    DOI 10.1038/s41416-022-02067-z, PubMed 36476658
  14. Stacchiotti S, Dürr HR, Schaefer IM, Woertler K, Haas R, Trama A, Caraceni A, Bajpai J, Baldi GG, Bernthal N, Blay JY, Boye K, Broto JM, Chen WT, Dei Tos PA, Desai J, Emhofer S, Eriksson M, Gronchi A, Gelderblom H, Hardes J, Hartmann W, Healey J, Italiano A, Jones RL et al. (2022)
    Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts
    Cancer Treat Rev, 112, 102491
    DOI 10.1016/j.ctrv.2022.102491, PubMed 36502615
  15. Chen J, Song Y, Li Y, Wei Y, Shen S, Zhao Y, You D, Su L, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Shen H, Christiani DC, Zhang R, Chen F (2022)
    A trans-omics assessment of gene-gene interaction in early-stage NSCLC
    Mol Oncol, 17 (1), 173-187
    DOI 10.1002/1878-0261.13345, PubMed 36408734
  16. Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD et al. (2022)
    Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
    Cancer Discov, 12 (12), 2930-2953
    DOI 10.1158/2159-8290.CD-21-0865, PubMed 36108220
  17. Seborova K, Hlavac V, Holy P, Bjørklund SS, Fleischer T, Rob L, Hruda M, Bouda J, Mrhalova M, Allah MMKAO, Vodicka P, Fiala O, Soucek P, Kristensen VN, Vodickova L, Vaclavikova R (2022)
    Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy
    Front Oncol, 12, 1016958
    DOI 10.3389/fonc.2022.1016958, PubMed 36531044
  18. Axcrona K, Aas K, Axcrona U, Skotheim RI (2022)
    Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
    Eur Urol, 83 (2), 183
    DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529
  19. Ganley IG, Simonsen A (2022)
    Diversity of mitophagy pathways at a glance
    J Cell Sci, 135 (23)
    DOI 10.1242/jcs.259748, PubMed 36504076
  20. Røssevold AH, Andresen NK, Bjerre CA, Gilje B, Jakobsen EH, Raj SX, Falk RS, Russnes HG, Jahr T, Mathiesen RR, Lømo J, Garred Ø, Chauhan SK, Lereim RR, Dunn C, Naume B, Kyte JA (2022)
    Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
    Nat Med, 28 (12), 2573-2583
    DOI 10.1038/s41591-022-02126-1, PubMed 36482103
  21. Cichocki F, Bjordahl R, Goodridge JP, Mahmood S, Gaidarova S, Abujarour R, Davis ZB, Merino A, Tuininga K, Wang H, Kumar A, Groff B, Witty A, Bonello G, Huffman J, Dailey T, Lee TT, Malmberg KJ, Walcheck B, Höpken U, Rehm A, Valamehr B, Miller JS (2022)
    Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
    Nat Commun, 13 (1), 7341
    DOI 10.1038/s41467-022-35127-2, PubMed 36446823
  22. Børø S, Thoresen S, Helland Å (2022)
    Improvements in survival for patients with stage IV adenocarcinoma in the lung, diagnosed between 2010 - 2020 - A population-based registry study from Norway
    Front Oncol, 12, 1017902
    DOI 10.3389/fonc.2022.1017902, PubMed 36523970
  23. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
    DOI 10.3389/fonc.2022.1040730, PubMed 36523963
  24. Castro-Mondragon JA, Aure MR, Lingjærde OC, Langerød A, Martens JWM, Børresen-Dale AL, Kristensen VN, Mathelier A (2022)
    Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
    Nucleic Acids Res, 50 (21), 12131-12148
    DOI 10.1093/nar/gkac1143, PubMed 36477895
  25. Fleten KG, Hyldbakk A, Einen C, Benjakul S, Strand BL, Davies CL, Mørch Ý, Flatmark K (2022)
    Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
    Mar Drugs, 20 (12)
    DOI 10.3390/md20120744, PubMed 36547891
  26. Nunes-Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Taskén KA, Mælandsmo GM, Fodstad Ø, Llarena R, Pulido R, López JI (2022)
    Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
    Pathol Res Pract, 241, 154243
    DOI 10.1016/j.prp.2022.154243, PubMed 36481650
  27. Tornes AJK, Stenberg VY, Larsen RH, Bruland ØS, Revheim ME, Juzeniene A (2022)
    Targeted alpha therapy with the 224Ra/212Pb-TCMC-TP-3 dual alpha solution in a multicellular tumor spheroid model of osteosarcoma
    Front Med (Lausanne), 9, 1058863
    DOI 10.3389/fmed.2022.1058863, PubMed 36507500
  28. Ghiasvand R, Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Karlstad Ø, Juzeniene A, Larsen IK, Green AC, Veierød MB, Robsahm TE (2022)
    Use of antihypertensive drugs and risk of cutaneous melanoma: a nationwide nested case-control study
    Int J Epidemiol (in press)
    DOI 10.1093/ije/dyac223, PubMed 36413027
  29. Horndalsveen H, Alver TN, Dalsgaard AM, Rogg LV, Helbekkmo N, Grønberg BH, Halvorsen TO, Ramberg C, Haakensen VD, Öjlert ÅK, Bjaanaes MM, Helland Å (2022)
    Atezolizumab and stereotactic body radiotherapy in patients with advanced non-small cell lung cancer: safety, clinical activity and ctDNA responses-the ComIT-1 trial
    Mol Oncol, 17 (3), 487-498
    DOI 10.1002/1878-0261.13330, PubMed 36330681
  30. Yri OE, Aass N, Kaasa S (2022)
    [Not Available]
    Tidsskr Nor Laegeforen, 142 (17)
    DOI 10.4045/tidsskr.22.0696, PubMed 36416654
  31. Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
    Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
    EMBO J, 41 (24), e112677
    DOI 10.15252/embj.2022112677, PubMed 36408828
  32. Møller P (2022)
    The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
    Hered Cancer Clin Pract, 20 (1), 37
    DOI 10.1186/s13053-022-00243-z, PubMed 36411472
  33. Ravindran V, Wagoner J, Athanasiadis P, Den Hartigh AB, Sidorova JM, Ianevski A, Fink SL, Frigessi A, White J, Polyak SJ, Aittokallio T (2022)
    Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network
    Brief Bioinform, 23 (6)
    DOI 10.1093/bib/bbac456, PubMed 36305426
  34. Huse K, Bai B, Hilden VI, Bollum LK, Våtsveen TK, Munthe LA, Smeland EB, Irish JM, Wälchli S, Myklebust JH (2022)
    Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression
    J Immunol, 209 (10), 2042-2053
    DOI 10.4049/jimmunol.2200144, PubMed 36426942
  35. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
    Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
    Cancers (Basel), 14 (22)
    DOI 10.3390/cancers14225603, PubMed 36428697
  36. Stanciu SG, Hristu R, Stanciu GA, Tranca DE, Eftimie L, Dumitru A, Costache M, Stenmark HA, Manders H, Cherian A, Tark-Dame M, Manders EMM (2022)
    Super-resolution re-scan second harmonic generation microscopy
    Proc Natl Acad Sci U S A, 119 (47), e2214662119
    DOI 10.1073/pnas.2214662119, PubMed 36375085
  37. Wenzel EM, Raiborg C (2022)
    ER-endosome contacts master the ins and outs of secretory endosomes
    J Cell Biol, 221 (12)
    DOI 10.1083/jcb.202210033, PubMed 36355088
  38. Maggadóttir SM, Kvalheim G, Wernhoff P, Sæbøe-Larssen S, Revheim ME, Josefsen D, Wälchli S, Helland Å, Inderberg EM (2022)
    A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT)
    Front Oncol, 12, 1031232
    DOI 10.3389/fonc.2022.1031232, PubMed 36439452
  39. Bousquet PA, Manna D, Sandvik JA, Arntzen MØ, Moreno E, Sandvig K, Krengel U (2022)
    SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7
    Front Immunol, 13, 994790
    DOI 10.3389/fimmu.2022.994790, PubMed 36439103
  40. Majhi RK, Pourteymour S (2022)
    Piezo1 activation by stretching of uterine myometrium supports pregnancy and prevents preterm labour
    J Physiol, 601 (4), 719-721
    DOI 10.1113/JP283810, PubMed 36266732
  41. Callesen LB, Takacova T, Hamfjord J, Würschmidt F, Oldhafer KJ, Brüning R, Arnold D, Spindler KG (2022)
    Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis
    Ther Adv Med Oncol, 14, 17588359221133171
    DOI 10.1177/17588359221133171, PubMed 36339929
  42. Momayyezi P, Malmberg KJ, Hammer Q (2022)
    Small Interfering RNA Delivery Into Primary Human Natural Killer Cells for Functional Gene Analyses
    Curr Protoc, 2 (11), e613
    DOI 10.1002/cpz1.613, PubMed 36440989
  43. Aronson JH, Skånland SS, Roeker LE, Thompson MC, Mato AR (2022)
    Approach to a patient with "double refractory" chronic lymphocytic leukemia: "Double, double toil and trouble" (Shakespeare)
    Am J Hematol, 97 Suppl 2, S19-S25
    DOI 10.1002/ajh.26682, PubMed 36125036
  44. Haroun-Izquierdo A, Vincenti M, Netskar H, van Ooijen H, Zhang B, Bendzick L, Kanaya M, Momayyezi P, Li S, Wiiger MT, Hoel HJ, Krokeide SZ, Kremer V, Tjonnfjord G, Berggren S, Wikström K, Blomberg P, Alici E, Felices M, Önfelt B, Höglund P, Valamehr B, Ljunggren HG, Björklund A, Hammer Q et al. (2022)
    Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
    J Immunother Cancer, 10 (11)
    DOI 10.1136/jitc-2022-005577, PubMed 36319065
  45. Lomakin A, Svedlund J, Strell C, Gataric M, Shmatko A, Rukhovich G, Park JS, Ju YS, Dentro S, Kleshchevnikov V, Vaskivskyi V, Li T, Bayraktar OA, Pinder S, Richardson AL, Santagata S, Campbell PJ, Russnes H, Gerstung M, Nilsson M, Yates LR (2022)
    Spatial genomics maps the structure, nature and evolution of cancer clones
    Nature, 611 (7936), 594-602
    DOI 10.1038/s41586-022-05425-2, PubMed 36352222
  46. Pulido R, Nunes-Xavier CE (2022)
    Hopes on immunotherapy targeting B7-H3 in neuroblastoma
    Transl Oncol, 27, 101580
    DOI 10.1016/j.tranon.2022.101580, PubMed 36327699
  47. Du H, Yang F, Yao C, Lv W, Peng H, Stanciu SG, Stenmark HA, Song YM, Jiang B, Wu A (2022)
    "Double-punch" strategy against triple-negative breast cancer via a synergistic therapy of magneto-mechanical force enhancing NIR-II hypothermal ablation
    Biomaterials, 291, 121868
    DOI 10.1016/j.biomaterials.2022.121868, PubMed 36332286
  48. Nævdal G, Rofstad EK, Søreide K, Evje S (2022)
    Fluid-sensitive migration mechanisms predict association between metastasis and high interstitial fluid pressure in pancreatic cancer
    J Biomech, 145, 111362
    DOI 10.1016/j.jbiomech.2022.111362, PubMed 36368256
  49. Wei Q, Taskén K (2022)
    Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development
    Biochem J, 479 (20), 2219-2260
    DOI 10.1042/BCJ20210233, PubMed 36305711
  50. Eek Mariampillai A, Hauge S, Øynebråten I, Rødland GE, Corthay A, Syljuåsen RG (2022)
    Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells
    Front Oncol, 12, 981332
    DOI 10.3389/fonc.2022.981332, PubMed 36387237
  51. Girard N, Bar J, Garrido P, Garassino MC, McDonald F, Mornex F, Filippi AR, Smit HJM, Peters S, Field JK, Christoph DC, Sibille A, Fietkau R, Haakensen VD, Chouaid C, Markman B, Hiltermann TJN, Taus A, Sawyer W, Allen A, Chander P, Licour M, Solomon B (2022)
    Treatment Characteristics and Real-World Progression-Free Survival in Patients With Unresectable Stage III NSCLC Who Received Durvalumab After Chemoradiotherapy: Findings From the PACIFIC-R Study
    J Thorac Oncol, 18 (2), 181-193
    DOI 10.1016/j.jtho.2022.10.003, PubMed 36307040
  52. Thomassen M, Mesman RLS, Hansen TVO, Menendez M, Rossing M, Esteban-Sánchez A, Tudini E, Törngren T, Parsons MT, Pedersen IS, Teo SH, Kruse TA, Møller P, Borg Å, Jensen UB, Christensen LL, Singer CF, Muhr D, Santamarina M, Brandao R, Andresen BS, Feng BJ, Canson D, Richardson ME, Karam R et al. (2022)
    Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
    Hum Mutat, 43 (12), 1921-1944
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    Cancer Gene Ther, 29 (8-9), 1276-1284
    DOI 10.1038/s41417-022-00444-7, PubMed 35194199
  182. Fontugne J, Cai PY, Alnajar H, Bhinder B, Park K, Ye H, Beg S, Sailer V, Siddiqui J, Blattner-Johnson M, Croyle JA, Noorzad Z, Calagua C, MacDonald TY, Axcrona U, Bogaard M, Axcrona K, Scherr DS, Sanda MG, Johannessen B, Chinnaiyan AM, Elemento O, Skotheim RI, Rubin MA, Barbieri CE et al. (2022)
    Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
    JCI Insight, 7 (4)
    DOI 10.1172/jci.insight.155309, PubMed 35050902
  183. Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
    Waves of sumoylation support transcription dynamics during adipocyte differentiation
    Nucleic Acids Res, 50 (3), 1351-1369
    DOI 10.1093/nar/gkac027, PubMed 35100417
  184. Hammer Q, Dunst J, Christ W, Picarazzi F, Wendorff M, Momayyezi P, Huhn O, Netskar HK, Maleki KT, García M, Sekine T, Sohlberg E, Azzimato V, Aouadi M, Karolinska COVID-19 Study Group, Severe COVID-19 GWAS Group, Degenhardt F, Franke A, Spallotta F, Mori M, Michaëlsson J, Björkström NK, Rückert T, Romagnani C, Horowitz A et al. (2022)
    SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
    Cell Rep, 38 (10), 110503
    DOI 10.1016/j.celrep.2022.110503, PubMed 35235832
  185. Engedal N, Proikas-Cezanne T, Albertini MC, Žerovnik E, Lane JD (2022)
    Transautophagy: Research and Translation of Autophagy Knowledge 2020
    Oxid Med Cell Longev, 2022, 9792132
    DOI 10.1155/2022/9792132, PubMed 35340207
  186. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
    miR-486-5p expression is regulated by DNA methylation in osteosarcoma
    BMC Genomics, 23 (1), 142
    DOI 10.1186/s12864-022-08346-6, PubMed 35172717
  187. Nilsen A, Hillestad T, Skingen VE, Aarnes EK, Fjeldbo CS, Hompland T, Evensen TS, Stokke T, Kristensen GB, Grallert B, Lyng H (2022)
    miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
    Mol Oncol, 16 (6), 1402-1419
    DOI 10.1002/1878-0261.13184, PubMed 35064630
  188. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  189. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
    Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
    J Infect Dis, 225 (4), 661-674
    DOI 10.1093/infdis/jiaa714, PubMed 33216130
  190. Umu SU, Langseth H, Zuber V, Helland Å, Lyle R, Rounge TB (2022)
    Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
    Elife, 11
    DOI 10.7554/eLife.71035, PubMed 35147498
  191. Mateus D, Wiedlocha A (2022)
    FGF-FGFR signaling promotes the development of invasive cervical cancer
    FEBS J, 289 (12), 3419-3421
    DOI 10.1111/febs.16384, PubMed 35146913
  192. Holland P, Quintana EM, Khezri R, Schoborg TA, Rusten TE (2022)
    Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
    Sci Rep, 12 (1), 2056
    DOI 10.1038/s41598-022-05991-5, PubMed 35136137
  193. Møller P, Evans DG (2022)
    Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030879, PubMed 35160330
  194. Blijdorp CJ, Burger D, Llorente A, Martens-Uzunova ES, Erdbrügger U (2022)
    Extracellular Vesicles as Novel Players in Kidney Disease
    J Am Soc Nephrol, 33 (3), 467-471
    DOI 10.1681/ASN.2021091232, PubMed 35131841
  195. Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ (2022)
    Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
    Blood, 139 (5), 704-716
    DOI 10.1182/blood.2021013233, PubMed 34699594
  196. Nissen-Meyer J, Skotland T, Boye E (2022)
    Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
    EMBO Rep, 23 (3), e54431
    DOI 10.15252/embr.202154431, PubMed 35156749
  197. Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M (2022)
    Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
    Cells, 11 (3)
    DOI 10.3390/cells11030522, PubMed 35159330
  198. Enserink JM, Chymkowitch P (2022)
    Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
    Int J Mol Sci, 23 (3)
    DOI 10.3390/ijms23031293, PubMed 35163213
  199. Kyte JA (2022)
    Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers
    Cancers (Basel), 14 (3)
    DOI 10.3390/cancers14030571, PubMed 35158839
  200. Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q (2022)
    Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
    Biomedicines, 10 (2)
    DOI 10.3390/biomedicines10020232, PubMed 35203441
  201. Xia YY, Gronwald J, Karlan B, Lubinski J, McCuaig JM, Brooks J, Moller P, Eisen A, Sun S, Senter L, Bordeleau L, Neuhausen SL, Singer CF, Tung N, Foulkes WD, Sun P, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2022)
    Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 164 (3), 514-521
    DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280
  202. Ballester PJ, Stevens R, Haibe-Kains B, Huang RS, Aittokallio T (2022)
    Artificial intelligence for drug response prediction in disease models
    Brief Bioinform, 23 (1)
    DOI 10.1093/bib/bbab450, PubMed 34655289
  203. Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
    STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
    Am J Cancer Res, 12 (1), 327-336
    PubMed 35141021
  204. Wolf J, Helland Å, Oh IJ, Migliorino MR, Dziadziuszko R, Wrona A, de Castro J, Mazieres J, Griesinger F, Chlistalla M, Cardona A, Ruf T, Trunzer K, Smoljanovic V, Novello S (2022)
    Final efficacy and safety data, and exploratory molecular profiling from the phase III ALUR study of alectinib versus chemotherapy in crizotinib-pretreated ALK-positive non-small-cell lung cancer
    ESMO Open, 7 (1), 100333
    DOI 10.1016/j.esmoop.2021.100333, PubMed 35042152
  205. Alaña L, Nunes-Xavier CE, Zaldumbide L, Martin-Guerrero I, Mosteiro L, Alba-Pavón P, Villate O, García-Obregón S, González-García H, Herraiz R, Astigarraga I, Pulido R, García-Ariza M (2022)
    Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
    Cancers (Basel), 14 (2)
    DOI 10.3390/cancers14020421, PubMed 35053583
  206. Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
    A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
    NAR Cancer, 4 (1), zcab051
    DOI 10.1093/narcan/zcab051, PubMed 35047825
  207. Chakraborty S, Woldemariam NT, Visnovska T, Rise ML, Boyce D, Santander J, Andreassen R (2022)
    Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
    Biology (Basel), 11 (1)
    DOI 10.3390/biology11010130, PubMed 35053128
  208. Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M (2022)
    HLA-independent T cell receptors for targeting tumors with low antigen density
    Nat Med, 28 (2), 345-352
    DOI 10.1038/s41591-021-01621-1, PubMed 35027758
  209. Skotheim RI, Axcrona U, Axcrona K (2022)
    Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
    Eur Urol, 81 (4), 431
    DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159
  210. Hjerkind KV, Johansson ALV, Trewin CB, Russnes HG, Ursin G (2022)
    Incidence of breast cancer subtypes in immigrant and non-immigrant women in Norway
    Breast Cancer Res, 24 (1), 4
    DOI 10.1186/s13058-021-01498-5, PubMed 35012613
  211. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy, 18 (2), 467-469
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  212. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci, 1510 (1), 79-99
    DOI 10.1111/nyas.14745, PubMed 35000205
  213. Ji X, Lin L, Fan J, Li Y, Wei Y, Shen S, Su L, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Zhang R, Chen F, Christiani DC (2022)
    Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC
    Mol Oncol, 16 (3), 717-731
    DOI 10.1002/1878-0261.13167, PubMed 34932879
  214. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
    DOI 10.1093/nar/gkab1101, PubMed 34850127
  215. Ahearn TU, Zhang H, Michailidou K, Milne RL, Bolla MK, Dennis J, Dunning AM, Lush M, Wang Q, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Augustinsson A, Baten A, Becher H, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H et al. (2022)
    Common variants in breast cancer risk loci predispose to distinct tumor subtypes
    Breast Cancer Res, 24 (1), 2
    DOI 10.1186/s13058-021-01484-x, PubMed 34983606
  216. Sivanesan S, Taskén KA, Grytli HH (2022)
    Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
    JAMA Netw Open, 5 (1), e2145230
    DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
  217. Athanasiadis P, Ianevski A, Skånland SS, Aittokallio T (2022)
    Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells
    Methods Mol Biol, 2449, 327-348
    DOI 10.1007/978-1-0716-2095-3_14, PubMed 35507270
  218. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    J Acquir Immune Defic Syndr, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817, PubMed 34878437
  219. Nguyen L, Nguyen E, Tran C, Nguyen K, Devarajan A, Berg K, Hirschberg H (2022)
    Sonochemical Internalization of Bleomycin Inhibits Adenocarcinoma Breast Tumor Development in an Orthotopic Rat Model
    J Environ Pathol Toxicol Oncol, 41 (2), 25-35
    DOI 10.1615/JEnvironPatholToxicolOncol.2021040536, PubMed 35695649
  220. Helland Å, Andersen KK, Myklebust TÅ, Johannesen TB, Aarøe J, Enerly E (2022)
    EGFR-mutation testing and TKI treatment patterns in locally advanced and metastatic NSCLC in Norway - A nationwide retrospective cohort study
    Cancer Treat Res Commun, 33, 100636
    DOI 10.1016/j.ctarc.2022.100636, PubMed 36155129
  221. Kryeziu K, Bergsland CH, Guren TK, Sveen A, Lothe RA (2022)
    Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
    Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
    DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193
  222. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  223. Bajor M, Graczyk-Jarzynka A, Marhelava K, Burdzinska A, Muchowicz A, Goral A, Zhylko A, Soroczynska K, Retecki K, Krawczyk M, Klopotowska M, Pilch Z, Paczek L, Malmberg KJ, Wälchli S, Winiarska M, Zagozdzon R (2022)
    PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells
    J Immunother Cancer, 10 (1)
    DOI 10.1136/jitc-2021-002500, PubMed 35078921

Publications 2021

  1. Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A (2021)
    Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
    Sci Total Environ, 814, 152732
    DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025
  2. Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
    Cell Rep, 37 (13), 110186
    DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
  3. Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
    E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
    Mol Oncol, 16 (12), 2312-2329
    DOI 10.1002/1878-0261.13159, PubMed 34890102
  4. White JM, Schiffer JT, Bender Ignacio RA, Xu S, Kainov D, Ianevski A, Aittokallio T, Frieman M, Olinger GG, Polyak SJ (2021)
    Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
    mBio, 12 (6), e0334721
    DOI 10.1128/mbio.03347-21, PubMed 34933447
  5. Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy, 18 (8), 1915-1931
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  6. Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol Oncol, 16 (5), 1153-1170
    DOI 10.1002/1878-0261.13153, PubMed 34861096
  7. Reint G, Li Z, Labun K, Keskitalo S, Soppa I, Mamia K, Tolo E, Szymanska M, Meza-Zepeda LA, Lorenz S, Cieslar-Pobuda A, Hu X, Bordin DL, Staerk J, Valen E, Schmierer B, Varjosalo M, Taipale J, Haapaniemi E (2021)
    Rapid genome editing by CRISPR-Cas9-POLD3 fusion
    Elife, 10
    DOI 10.7554/eLife.75415, PubMed 34898428
  8. Jørgensen SF, Buechner J, Myhre AE, Galteland E, Spetalen S, Kulseth MA, Sorte HS, Holla ØL, Lundman E, Alme C, Heier I, Flægstad T, Fløisand Y, Benneche A, Fevang B, Aukrust P, Stray-Pedersen A, Gedde-Dahl T, Nordøy I (2021)
    A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
    J Clin Immunol, 42 (2), 404-420
    DOI 10.1007/s10875-021-01189-y, PubMed 34893945
  9. Larsen SG, Goscinski MA, Dueland S, Steigen SE, Hofsli E, Torgunrud A, Lund-Iversen M, Dagenborg VJ, Flatmark K, Sorbye H (2021)
    Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
    Br J Cancer, 126 (5), 726-735
    DOI 10.1038/s41416-021-01620-6, PubMed 34887523
  10. Nunes-Xavier CE, Zaldumbide L, Mosteiro L, López-Almaraz R, García de Andoin N, Aguirre P, Emaldi M, Torices L, López JI, Pulido R (2021)
    Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets
    Front Cell Dev Biol, 9, 811297
    DOI 10.3389/fcell.2021.811297, PubMed 34957126
  11. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
  12. Gansmo LB, Sofiyeva N, Bjørnslett M, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
    Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
    Sci Rep, 11 (1), 23463
    DOI 10.1038/s41598-021-02820-z, PubMed 34873230
  13. Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, Knetter C, Odabasi MC, Bollineni RC, Yang X, Foldvari Z, Böschen ML, Taraldsrud E, Strønen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjønnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT et al. (2021)
    T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
    Nat Biotechnol, 40 (4), 488-498
    DOI 10.1038/s41587-021-01089-x, PubMed 34873326
  14. Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
    Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
    Hepatology, 75 (1), 59-73
    DOI 10.1002/hep.32125, PubMed 34435693
  15. Lien TG, Ohnstad HO, Lingjærde OC, Vallon-Christersson J, Aaserud M, Sveli MAT, Borg Å, Osbreac OBO, Garred Ø, Borgen E, Naume B, Russnes H, Sørlie T (2021)
    Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
    Cancers (Basel), 13 (23)
    DOI 10.3390/cancers13236118, PubMed 34885228
  16. Tamhane T, Njenga RW, Burden RE, Bueth H, Maelandsmo GM, Haugen MH, Scott CJ, Brix K (2021)
    Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
    Appl. Sci.-Basel, 11 (24), 11936
    DOI 10.3390/app112411936
  17. Klopotowska M, Bajor M, Graczyk-Jarzynka A, Kraft A, Pilch Z, Zhylko A, Firczuk M, Baranowska I, Lazniewski M, Plewczynski D, Goral A, Soroczynska K, Domagala J, Marhelava K, Slusarczyk A, Retecki K, Ramji K, Krawczyk M, Temples MN, Sharma B, Lachota M, Netskar H, Malmberg KJ, Zagozdzon R, Winiarska M (2021)
    PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress
    Cancer Immunol Res, 10 (2), 228-244
    DOI 10.1158/2326-6066.CIR-20-1023, PubMed 34853030
  18. Hamfjord J, Myklebust TÅ, Larsen IK, Kure EH, Glimelius B, Guren TK, Tveit KM, Guren MG (2021)
    Survival Trends of Right- and Left-Sided Colon Cancer across Four Decades: A Norwegian Population-Based Study
    Cancer Epidemiol Biomarkers Prev, 31 (2), 342-351
    DOI 10.1158/1055-9965.EPI-21-0555, PubMed 34853022
  19. Hølmebakk T, Boye K (2021)
    Correction to: ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (Suppl 3), 873
    DOI 10.1245/s10434-021-09939-3, PubMed 33829360
  20. Li H, Engel C, de la Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2021)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (1), 119-129
    DOI 10.1016/j.gim.2021.08.016, PubMed 34906479
  21. Grigalavicius M, Mastrangelopoulou M, Berg K, Arous D, Ménard M, Raabe-Henriksen T, Brondz E, Siem S, Görgen A, Edin NFJ, Malinen E, Theodossiou TA (2021)
    Publisher Correction: Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
    Nat Commun, 12 (1), 7073
    DOI 10.1038/s41467-021-27175-x, PubMed 34848706
  22. Li RG, Lindland K, Bønsdorff TB, Westrøm S, Larsen RH (2021)
    A Novel Single-Step-Labeled 212Pb-CaCO3 Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice
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  217. Jaiswal A, Gautam P, Pietilä EA, Timonen S, Nordström N, Akimov Y, Sipari N, Tanoli Z, Fleischer T, Lehti K, Wennerberg K, Aittokallio T (2021)
    Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
    Mol Syst Biol, 17 (3), e9526
    DOI 10.15252/msb.20209526, PubMed 33750001
  218. Helwa R, Gansmo LB, Bjørnslett M, Halle MK, Werner HMJ, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
    Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
    Biomarkers, 26 (4), 302-308
    DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
  219. Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
    Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
    Sci Rep, 11 (1), 4613
    DOI 10.1038/s41598-021-84268-9, PubMed 33633289
  220. Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
    Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
    Autophagy, 17 (4), 1046-1048
    DOI 10.1080/15548627.2021.1887548, PubMed 33629888
  221. Akimov Y, Aittokallio T (2021)
    Re-defining synthetic lethality by phenotypic profiling for precision oncology
    Cell Chem Biol, 28 (3), 246-256
    DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125
  222. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
    A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
    Sci Transl Med, 13 (582)
    DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
  223. Siddiqui FA, Parkkola H, Vukic V, Oetken-Lindholm C, Jaiswal A, Kiriazis A, Pavic K, Aittokallio T, Salminen TA, Abankwa D (2021)
    Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling
    Cancers (Basel), 13 (4)
    DOI 10.3390/cancers13040927, PubMed 33672199
  224. Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
    DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
    Atherosclerosis, 324, 123-132
    DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
  225. Gaustad JV, Simonsen TG, Hansem LMK, Rofstad EK (2021)
    Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
    Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
    DOI 10.1007/s00259-021-05243-0, PubMed 33606081
  226. Juzeniene A, Stenberg VY, Bruland ØS, Larsen RH (2021)
    Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
    Cancers (Basel), 13 (4)
    DOI 10.3390/cancers13040779, PubMed 33668474
  227. Tanoli Z, Vähä-Koskela M, Aittokallio T (2021)
    Artificial intelligence, machine learning, and drug repurposing in cancer
    Expert Opin Drug Discov, 16 (9), 977-989
    DOI 10.1080/17460441.2021.1883585, PubMed 33543671
  228. Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
    Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
    Cancer Immunol Immunother, 70 (9), 2617-2624
    DOI 10.1007/s00262-021-02876-w, PubMed 33580363
  229. Ben-Elazar S, Aure MR, Jonsdottir K, Leivonen SK, Kristensen VN, Janssen EAM, Kleivi Sahlberg K, Lingjærde OC, Yakhini Z (2021)
    miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
    PLoS Comput Biol, 17 (2), e1008608
    DOI 10.1371/journal.pcbi.1008608, PubMed 33566819
  230. Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
    The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
    J Cell Sci, 134 (3)
    DOI 10.1242/jcs.250670, PubMed 33468622
  231. Davydova E, Shimazu T, Schuhmacher MK, Jakobsson ME, Willemen HLDM, Liu T, Moen A, Ho AYY, Małecki J, Schroer L, Pinto R, Suzuki T, Grønsberg IA, Sohtome Y, Akakabe M, Weirich S, Kikuchi M, Olsen JV, Dohmae N, Umehara T, Sodeoka M, Siino V, McDonough MA, Eijkelkamp N, Schofield CJ et al. (2021)
    The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
    Nat Commun, 12 (1), 891
    DOI 10.1038/s41467-020-20670-7, PubMed 33563959
  232. Krüger K, Silwal-Pandit L, Wik E, Straume O, Stefansson IM, Borgen E, Garred Ø, Naume B, Engebraaten O, Akslen LA (2021)
    Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
    Sci Rep, 11 (1), 3388
    DOI 10.1038/s41598-021-81914-0, PubMed 33564016
  233. Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
    Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
    FEBS Open Bio, 11 (3), 724-740
    DOI 10.1002/2211-5463.13098, PubMed 33512765
  234. Gorgen A, Guttormsen M, Larsen AC, Siem S, Adli E, Edin NFJ, Gjersdal H, Henriksen G, Malinen E, Modamio V, Schoultz B, Sobas PA, Theodossiou TA, Wikne JC (2021)
    The Oslo Cyclotron Laboratory
    Eur. Phys. J. Plus, 136 (2), 181
    DOI 10.1140/epjp/s13360-021-01150-3
  235. Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
    Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
    Int J Environ Res Public Health, 18 (4)
    DOI 10.3390/ijerph18041470, PubMed 33557277
  236. Berishvili E, Kaiser L, Cohen M, Berney T, Scholz H, Floisand Y, Mattsson J (2021)
    Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
    Stem Cell Rev Rep, 17 (1), 63-70
    DOI 10.1007/s12015-020-10004-x, PubMed 32696426
  237. Skotland T, Sandvig K (2021)
    Transport of nanoparticles across the endothelial cell layer
    Nano Today, 36, 101029
    DOI 10.1016/j.nantod.2020.101029
  238. Ianevski A, Lahtela J, Javarappa KK, Sergeev P, Ghimire BR, Gautam P, Vähä-Koskela M, Turunen L, Linnavirta N, Kuusanmäki H, Kontro M, Porkka K, Heckman CA, Mattila P, Wennerberg K, Giri AK, Aittokallio T (2021)
    Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
    Sci Adv, 7 (8)
    DOI 10.1126/sciadv.abe4038, PubMed 33608276
  239. Johansson ALV, Trewin CB, Fredriksson I, Reinertsen KV, Russnes H, Ursin G (2021)
    In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study
    Breast Cancer Res, 23 (1), 17
    DOI 10.1186/s13058-021-01393-z, PubMed 33526044
  240. Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
    Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
    Toxins (Basel), 13 (2)
    DOI 10.3390/toxins13020102, PubMed 33573355
  241. Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
    FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
    Commun Biol, 4 (1), 127
    DOI 10.1038/s42003-021-01647-8, PubMed 33514811
  242. Sakurai M, Mori T, Kato K, Kanaya M, Mizuno S, Shiratori S, Wakayama T, Uchida N, Kobayashi H, Kubo K, Amano I, Ohta T, Miyazaki Y, Kanda J, Fukuda T, Atsuta Y, Kondo E, Adult Lymphoma Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT) (2021)
    Outcome of allogeneic hematopoietic stem cell transplantation for follicular lymphoma relapsing after autologous transplantation: analysis of the Japan Society for Hematopoietic Cell Transplantation
    Bone Marrow Transplant, 56 (6), 1462-1466
    DOI 10.1038/s41409-020-01192-8, PubMed 33514920
  243. Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
    Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
    JCO Precis Oncol, 5
    DOI 10.1200/PO.20.00086, PubMed 34036235
  244. Hompland T, Fjeldbo CS, Lyng H (2021)
    Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
    Cancers (Basel), 13 (3)
    DOI 10.3390/cancers13030499, PubMed 33525508
  245. Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
    MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
    Mol Genet Metab Rep, 26, 100710
    DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904
  246. Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
    Editorial: Genomic Colocalization and Enrichment Analyses
    Front Genet, 11, 617876
    DOI 10.3389/fgene.2020.617876, PubMed 33574832
  247. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
  248. Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
    Wetting regulates autophagy of phase-separated compartments and the cytosol
    Nature, 591 (7848), 142-146
    DOI 10.1038/s41586-020-2992-3, PubMed 33473217
  249. Breast Cancer Association Consortium, Dorling L, Carvalho S, Allen J, González-Neira A, Luccarini C, Wahlström C, Pooley KA, Parsons MT, Fortuno C, Wang Q, Bolla MK, Dennis J, Keeman R, Alonso MR, Álvarez N, Herraez B, Fernandez V, Núñez-Torres R, Osorio A, Valcich J, Li M, Törngren T, Harrington PA, Baynes C et al. (2021)
    Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
    N Engl J Med, 384 (5), 428-439
    DOI 10.1056/NEJMoa1913948, PubMed 33471991
  250. Galili B, Tekpli X, Kristensen VN, Yakhini Z (2021)
    Efficient gene expression signature for a breast cancer immuno-subtype
    PLoS One, 16 (1), e0245215
    DOI 10.1371/journal.pone.0245215, PubMed 33434192
  251. Skånland SS, Mato AR (2021)
    Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
    Blood Adv, 5 (1), 334-343
    DOI 10.1182/bloodadvances.2020003423, PubMed 33570649
  252. Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
    Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 187 (2), 515-523
    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
  253. Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
    Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
    Mol Oncol, 15 (4), 830-845
    DOI 10.1002/1878-0261.12885, PubMed 33325154
  254. Otterhaug T, Janetzki S, Welters MJP, Håkerud M, Nedberg AG, Edwards VT, Boekestijn S, Loof NM, Selbo PK, Olivecrona H, van der Burg SH, Høgset A (2021)
    Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
    Front Immunol, 11, 576756
    DOI 10.3389/fimmu.2020.576756, PubMed 33488576
  255. Terkelsen T, Pernemalm M, Gromov P, Børresen-Dale AL, Krogh A, Haakensen VD, Lethiö J, Papaleo E, Gromova I (2021)
    High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
    Mol Oncol, 15 (2), 429-461
    DOI 10.1002/1878-0261.12850, PubMed 33176066
  256. Sharma A, Colonna G (2021)
    System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
    Mol Diagn Ther, 25 (1), 9-27
    DOI 10.1007/s40291-020-00505-3, PubMed 33475988
  257. Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
    From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
    Prog Chem Org Nat Prod, 115, 59-114
    DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641
  258. Sioud M (2021)
    RNA Interference: Story and Mechanisms
    Methods Mol Biol, 2282, 1-15
    DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566
  259. Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, Leusen J, Andersen JT (2021)
    Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
    MAbs, 13 (1), 1893888
    DOI 10.1080/19420862.2021.1893888, PubMed 33691596
  260. Li RG, Napoli E, Jorstad IS, Bønsdorff TB, Juzeniene A, Bruland ØS, Larsen RH, Westrøm S (2021)
    Calcium Carbonate Microparticles as Carriers of 224Ra: Impact of Specific Activity in Mice with Intraperitoneal Ovarian Cancer
    Curr Radiopharm, 14 (2), 145-153
    DOI 10.2174/1874471013666201201102056, PubMed 33261548
  261. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751

Publications 2020

  1. Bergeron DE, Collins SM, Pibida L, Cessna JT, Fitzgerald R, Zimmerman BE, Ivanov P, Keightley JD, Napoli E (2020)
    Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison
    Appl Radiat Isot, 170, 109572
    DOI 10.1016/j.apradiso.2020.109572, PubMed 33461017
  2. Pulkkinen OI, Gautam P, Mustonen V, Aittokallio T (2020)
    Multiobjective optimization identifies cancer-selective combination therapies
    PLoS Comput Biol, 16 (12), e1008538
    DOI 10.1371/journal.pcbi.1008538, PubMed 33370253
  3. Öjlert ÅK, Nebdal D, Lund-Iversen M, Åstrøm Ellefsen R, Brustugun OT, Gran JM, Halvorsen AR, Helland Å (2020)
    Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer - predictors of response and impact of previous radiotherapy
    Acta Oncol, 60 (2), 149-156
    DOI 10.1080/0284186X.2020.1854851, PubMed 33356733
  4. Graim K, Gorenshteyn D, Robinson DG, Carriero NJ, Cahill JA, Chakrabarti R, Goldschmidt MH, Durham AC, Funk J, Storey JD, Kristensen VN, Theesfeld CL, Sorenmo KU, Troyanskaya OG (2020)
    Modeling molecular development of breast cancer in canine mammary tumors
    Genome Res, 31 (2), 337-347
    DOI 10.1101/gr.256388.119, PubMed 33361113
  5. Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Karlstad Ø, Juzeniene A, Ghiasvand R, Larsen IK, Green AC, Veierød MB, Robsahm TE (2020)
    Use of Immunomodulating Drugs and Risk of Cutaneous Melanoma: A Nationwide Nested Case-Control Study
    Clin Epidemiol, 12, 1389-1401
    DOI 10.2147/CLEP.S269446, PubMed 33376408
  6. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
    A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
    J Biol Chem, 296, 100179
    DOI 10.1074/jbc.RA120.015285, PubMed 33303632
  7. Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Körner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang X, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang W, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR et al. (2020)
    Anti-tumour immunity induces aberrant peptide presentation in melanoma
    Nature, 590 (7845), 332-337
    DOI 10.1038/s41586-020-03054-1, PubMed 33328638
  8. Flatin BTB, Vedeld HM, Pinto R, Langerud J, Lind GE, Lothe RA, Sveen A, Jeanmougin M (2020)
    Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
    Int J Cancer, 148 (7), 1652-1657
    DOI 10.1002/ijc.33425, PubMed 33284993
  9. Jacomin AC, Gohel R, Hussain Z, Varga A, Maruzs T, Eddison M, Sica M, Jain A, Moffat KG, Johansen T, Jenny A, Juhasz G, Nezis IP (2020)
    Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
    Life Sci Alliance, 4 (2)
    DOI 10.26508/lsa.202000965, PubMed 33318080
  10. Lachota M, Vincenti M, Winiarska M, Boye K, Zagożdżon R, Malmberg KJ (2020)
    Prospects for NK Cell Therapy of Sarcoma
    Cancers (Basel), 12 (12)
    DOI 10.3390/cancers12123719, PubMed 33322371
  11. Castañeda-Zegarra S, Zhang Q, Alirezaylavasani A, Fernandez-Berrocal M, Yao R, Oksenych V (2020)
    Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
    Aging (Albany NY), 12 (23), 23578-23597
    DOI 10.18632/aging.202346, PubMed 33289702
  12. Isaksen KT, Beiske K, Smeland EB, Jørgensen J, Brodtkorb M, Myklebust JH, Jerkeman M, Meriranta L, Karjalainen-Lindsberg ML, Leppä S, Scott DW, Holte H, Blaker YN (2020)
    The DLBCL90 gene-expression assay identifies double-hit lymphomas with high sensitivity in patients from two phase II clinical trials with high-risk diffuse large B-cell lymphoma
    EJHaem, 2 (1), 104-108
    DOI 10.1002/jha2.109, PubMed 35846101
  13. Ask EH, Tschan-Plessl A, Gjerdingen TJ, Sætersmoen ML, Hoel HJ, Wiiger MT, Olweus J, Wahlin BE, Lingjærde OC, Horowitz A, Cashen AF, Watkins M, Fehniger TA, Holte H, Kolstad A, Malmberg KJ (2020)
    A Systemic Protein Deviation Score Linked to PD-1+ CD8+ T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma
    Med, 2 (2), 180-195.e5
    DOI 10.1016/j.medj.2020.10.006, PubMed 35590201
  14. Refinetti P, Morgenthaler S, Thilly WG, Arstad C, Ekstrøm PO (2020)
    Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
    Front Oncol, 10, 523860
    DOI 10.3389/fonc.2020.523860, PubMed 33344219
  15. Köksal H, Dillard P, Juzeniene A, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2020)
    Combinatorial CAR design improves target restriction
    J Biol Chem, 296, 100116
    DOI 10.1074/jbc.RA120.016234, PubMed 33234592
  16. Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
    Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Genet Med, 23 (4), 705-712
    DOI 10.1038/s41436-020-01029-1, PubMed 33257847
  17. Julkunen H, Cichonska A, Gautam P, Szedmak S, Douat J, Pahikkala T, Aittokallio T, Rousu J (2020)
    Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects
    Nat Commun, 11 (1), 6136
    DOI 10.1038/s41467-020-19950-z, PubMed 33262326
  18. Landsverk HB, Sandquist LE, Bay LTE, Steurer B, Campsteijn C, Landsverk OJB, Marteijn JA, Petermann E, Trinkle-Mulcahy L, Syljuåsen RG (2020)
    WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
    Cell Rep, 33 (9), 108469
    DOI 10.1016/j.celrep.2020.108469, PubMed 33264625
  19. Tschan-Plessl A, Kalberer CP, Wieboldt R, Stern M, Siegler U, Wodnar-Filipowicz A, Gerull S, Halter J, Heim D, Tichelli A, Tsakiris DA, Malmberg KJ, Passweg JR, Bottos A (2020)
    Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma
    Cytotherapy, 23 (4), 329-338
    DOI 10.1016/j.jcyt.2020.09.009, PubMed 33268029
  20. Halvorsen AR, Haugen MH, Öjlert ÅK, Lund-Iversen M, Jørgensen L, Solberg S, Mælandsmo GM, Brustugun OT, Helland Å (2020)
    Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
    Front Oncol, 10, 590755
    DOI 10.3389/fonc.2020.590755, PubMed 33324562
  21. Wang T, Gautam P, Rousu J, Aittokallio T (2020)
    Systematic mapping of cancer cell target dependencies using high-throughput drug screening in triple-negative breast cancer
    Comput Struct Biotechnol J, 18, 3819-3832
    DOI 10.1016/j.csbj.2020.11.001, PubMed 33335681
  22. Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ (2020)
    Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
    EMBO J, 39 (24), e104948
    DOI 10.15252/embj.2020104948, PubMed 33226137
  23. Zhao S, Agafonov O, Azab A, Stokowy T, Hovig E (2020)
    Accuracy and efficiency of germline variant calling pipelines for human genome data
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