Publications

Publications published since 2018 from OUS - Institute for Cancer Research

1264 publications found (only first 1000 shown)

Publications 2023

  1. Spasevska I, Sharma A, Steen CB, Josefsson SE, Blaker YN, Kolstad A, Rustad EH, Meyer S, Isaksen K, Chellappa S, Kushekhar K, Beiske K, Førsund MS, Spetalen S, Holte H, Østenstad B, Brodtkorb M, Kimby E, Olweus J, Taskén K, Newman AM, Lorenz S, Smeland EB, Alizadeh AA, Huse K et al. (2023)
    Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
    Blood Adv, 7 (23), 7216-7230
    DOI 10.1182/bloodadvances.2023010158, PubMed 37695745
  2. Hindi N, Razak A, Rosembaum E, Jonczak E, Hamacher R, Rutkowski P, Bhadri VA, Skryd A, Brahmi M, Alshibany A, Jagodzinska-Mucha P, Bauer S, Connolly E, Gelderblom H, Boye K, Henon C, Bae S, Bogefors K, Vincenzi B, Martinez-Trufero J, Lopez-Martin JA, Redondo A, Valverde C, Blay JY, Moura DS et al. (2023)
    Efficacy of immune checkpoint inhibitors in alveolar soft-part sarcoma: results from a retrospective worldwide registry
    ESMO Open, 8 (6), 102045 (in press)
    DOI 10.1016/j.esmoop.2023.102045, PubMed 38016251
  3. Børø S, Thoresen S, Boge Brant S, Helland Å (2023)
    Initial investigation of using Norwegian health data for the purpose of external comparator arms - an example for non-small cell lung cancer
    Acta Oncol, 62 (12), 1642-1648
    DOI 10.1080/0284186X.2023.2264484, PubMed 37801361
  4. Chen Y, He L, Ianevski A, Ayuda-Durán P, Potdar S, Saarela J, Miettinen JJ, Kytölä S, Miettinen S, Manninen M, Heckman CA, Enserink JM, Wennerberg K, Aittokallio T (2023)
    Robust scoring of selective drug responses for patient-tailored therapy selection
    Nat Protoc (in press)
    DOI 10.1038/s41596-023-00903-x, PubMed 37996540
  5. Ibrahim EIK, Ellingsen EB, Mangsbo SM, Friberg LE (2023)
    Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
    Int Immunopharmacol, 126, 111225 (in press)
    DOI 10.1016/j.intimp.2023.111225, PubMed 37988911
  6. Christie C, Madsen SJ, Peng Q, Hirschberg H (2023)
    Macrophages as a photosensitizer delivery system for photodynamic therapy: Potential for the local treatment of resected glioblastoma
    Photodiagnosis Photodyn Ther, 103897 (in press)
    DOI 10.1016/j.pdpdt.2023.103897, PubMed 37984525
  7. Gjelberg HK, Helgeland L, Liseth K, Micci F, Sandnes M, Russnes HG, Reikvam H (2023)
    Long-Smoldering T-prolymphocytic Leukemia: A Case Report and a Review of the Literature
    Curr Oncol, 30 (11), 10007-10018
    DOI 10.3390/curroncol30110727, PubMed 37999147
  8. Al Outa A, Hicks S, Thambawita V, Andresen S, Enserink JM, Halvorsen P, Riegler MA, Knævelsrud H (2023)
    CELLULAR, A Cell Autophagy Imaging Dataset
    Sci Data, 10 (1), 806
    DOI 10.1038/s41597-023-02687-x, PubMed 37973836
  9. Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2023)
    JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
    Nucleic Acids Res (in press)
    DOI 10.1093/nar/gkad1059, PubMed 37962376
  10. Chojnacka M, Diamond B, Ziccheddu B, Rustad E, Maclachlan K, Papadimitriou M, Boyle EM, Blaney P, Usmani S, Morgan G, Landgren O, Maura F (2023)
    Impact of rare structural variant events in newly diagnosed multiple myeloma
    Clin Cancer Res (in press)
    DOI 10.1158/1078-0432.CCR-23-1045, PubMed 37939148
  11. García-Díaz N, Wei Q, Taskén K (2023)
    Small molecule inhibitors targeting regulatory T cells for cancer treatment
    Eur J Immunol, e2350448 (in press)
    DOI 10.1002/eji.202350448, PubMed 37937687
  12. Clement D, Szabo EK, Krokeide SZ, Wiiger MT, Vincenti M, Palacios D, Chang YT, Grimm C, Patel S, Stenmark H, Brech A, Majhi RK, Malmberg KJ (2023)
    The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
    J Immunol, 211 (9), 1348-1358
    DOI 10.4049/jimmunol.2300406, PubMed 37737664
  13. Ask EH, Tschan-Plessl A, Hoel HJ, Kolstad A, Holte H, Malmberg KJ (2023)
    MetaGate: Interactive Analysis of High-Dimensional Cytometry Data with Meta Data Integration
    bioRxiv
    DOI 10.1101/2023.10.27.564454, PubMed 37961421
  14. Solbakken AM, Sellevold S, Spasojevic M, Julsrud L, Emblemsvåg HL, Reims HM, Sørensen O, Thorgersen EB, Fauske L, Ågren JSM, Brennhovd B, Ryder T, Larsen SG, Flatmark K (2023)
    ASO Visual Abstract: Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
    Ann Surg Oncol, 30 (12), 7637-7638
    DOI 10.1245/s10434-023-14105-y, PubMed 37589802
  15. Leivonen SK, Friman T, Autio M, Vaittinen S, Jensen AW, D'Amore F, Hamilton-Dutoit SJ, Holte H, Beiske K, Kovanen PE, Räty R, Leppä S (2023)
    Characterization and clinical impact of the tumor microenvironment in post-transplant aggressive B-cell lymphomas
    Haematologica, 108 (11), 3044-3057
    DOI 10.3324/haematol.2023.282831, PubMed 37259566
  16. Migliano SM, Schultz SW, Wenzel EM, Takáts S, Liu D, Mørk S, Tan KW, Rusten TE, Raiborg C, Stenmark H (2023)
    Removal of hypersignaling endosomes by simaphagy
    Autophagy, 1-23 (in press)
    DOI 10.1080/15548627.2023.2267958, PubMed 37840274
  17. Zlygosteva O, Juvkam IS, Aass HCD, Galtung HK, Søland TM, Malinen E, Edin NFJ (2023)
    Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck
    Int J Mol Sci, 24 (20)
    DOI 10.3390/ijms242015218, PubMed 37894899
  18. Høland M, Berg KCG, Eilertsen IA, Bjerkehagen B, Kolberg M, Boye K, Lingjærde OC, Guren TK, Mandahl N, van den Berg E, Palmerini E, Smeland S, Picci P, Mertens F, Sveen A, Lothe RA (2023)
    Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
    EBioMedicine, 97, 104829
    DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931
  19. Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
    Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
    Hered Cancer Clin Pract, 21 (1), 19
    DOI 10.1186/s13053-023-00263-3, PubMed 37821984
  20. Hammer Q, Perica K, van Ooijen H, Mbofung R, Momayyezi P, Varady E, Martin KE, Pan Y, Jelcic M, Groff B, Abujarour R, Krokeide S, Lee T, Williams A, Goodridge JP, Valamehr B, Önfelt B, Sadelain M, Malmberg KJ (2023)
    Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells
    bioRxiv
    DOI 10.1101/2023.10.09.557143, PubMed 37873468
  21. Thorgersen EB, Solbakken AM, Strøm TK, Goscinski M, Spasojevic M, Larsen SG, Flatmark K (2023)
    Short-term results after robot-assisted surgery for primary rectal cancers requiring beyond total mesorectal excision in multiple compartments
    Scand J Surg, 14574969231200654 (in press)
    DOI 10.1177/14574969231200654, PubMed 37787437
  22. Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, Wiedlocha A, Otlewski J, Zakrzewska M (2023)
    Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
    Cell Mol Life Sci, 80 (10), 311
    DOI 10.1007/s00018-023-04964-9, PubMed 37783936
  23. Boyle EM, Blaney P, Stoeckle JH, Wang Y, Ghamlouch H, Gagler D, Braunstein M, Williams L, Tenenbaum A, Siegel A, Chen X, Varma G, Avigan J, Li A, Jinsi M, Kaminetzsky D, Arbini A, Montes L, Corre J, Rustad EH, Landgren O, Maura F, Walker BA, Bauer M, Bruno B et al. (2023)
    Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma
    Clin Cancer Res, 29 (19), 3901-3913
    DOI 10.1158/1078-0432.CCR-22-3209, PubMed 37449980
  24. Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T et al. (2023)
    A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
    Nat Cancer, 4 (10), 1474-1490
    DOI 10.1038/s43018-023-00642-8, PubMed 37783807
  25. Acosta Roa AM, Skingen VE, Rekstad BL, Undseth C, Rusten E, Hernes E, Guren MG, Malinen E (2023)
    Stability of metabolic tumor volume may enable radiotherapy dose painting in anal cancer
    Phys Med, 114, 103151
    DOI 10.1016/j.ejmp.2023.103151, PubMed 37813051
  26. Sandoz PA, Kuhnigk K, Szabo EK, Thunberg S, Erikson E, Sandström N, Verron Q, Brech A, Watzl C, Wagner AK, Alici E, Malmberg KJ, Uhlin M, Önfelt B (2023)
    Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
    Nat Commun, 14 (1), 6035
    DOI 10.1038/s41467-023-41634-7, PubMed 37758698
  27. Lachota M, Zielniok K, Palacios D, Kanaya M, Peena L, Hoel HJ, Wiiger MT, Kveberg L, Hautz W, Zagożdżon R, Malmberg KJ (2023)
    Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation
    EBioMedicine, 96, 104811
    DOI 10.1016/j.ebiom.2023.104811, PubMed 37741009
  28. Mo T, Brandal SHB, Geier OM, Engebråten O, Nilsen LB, Kristensen VN, Hole KH, Hompland T, Fleischer T, Seierstad T (2023)
    MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
    Cancers (Basel), 15 (18)
    DOI 10.3390/cancers15184662, PubMed 37760629
  29. Anzar I, Malone B, Samarakoon P, Vardaxis I, Simovski B, Fontenelle H, Meza-Zepeda LA, Stratford R, Keung EZ, Burgess M, Tawbi HA, Myklebost O, Clancy T (2023)
    The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition
    Front Immunol, 14, 1226445
    DOI 10.3389/fimmu.2023.1226445, PubMed 37799721
  30. Nähse V, Schink KO, Stenmark H (2023)
    ATPase-regulated autophagosome biogenesis
    Autophagy, 1-2 (in press)
    DOI 10.1080/15548627.2023.2255967, PubMed 37722386
  31. Kresse SH, Brandt-Winge S, Pharo H, Flatin BTB, Jeanmougin M, Vedeld HM, Lind GE (2023)
    Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood
    Clin Epigenetics, 15 (1), 151
    DOI 10.1186/s13148-023-01563-0, PubMed 37710283
  32. Kaur N, Carlsson SR, Lystad AH (2023)
    The separate axes of TECPR1 and ATG16L1 in CASM
    Autophagy, 1-2 (in press)
    DOI 10.1080/15548627.2023.2255462, PubMed 37676042
  33. Giang KA, Boxaspen T, Diao Y, Nilvebrant J, Kosugi-Kanaya M, Kanaya M, Krokeide SZ, Lehmann F, Svensson Gelius S, Malmberg KJ, Nygren PÅ (2023)
    Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells
    N Biotechnol, 77, 139-148
    DOI 10.1016/j.nbt.2023.09.002, PubMed 37673373
  34. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
    Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
    Mol Oncol, 17 (11), 2432-2450
    DOI 10.1002/1878-0261.13514, PubMed 37622176
  35. Isaksen KT, Galleberg R, Mastroianni MA, Rinde M, Rusten LS, Barzenje D, Ramslien F, Fluge O, Slaaen M, Meyer P, Liestol K, Smeland EB, Lingjarde OC, Holte H, Brodtkorb M (2023)
    The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
    Haematologica, 108 (9), 2454-2466
    DOI 10.3324/haematol.2022.282289, PubMed 36861406
  36. Rodgers-Fouche L, Arora S, Ricker C, Li D, Farooqi M, Balaguer F, Dominguez-Valentin M, Guillem JG, Kanth P, Liska D, Melson J, Mraz KA, Shirts BH, Vilar E, Katona BW, Hodan R (2023)
    Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey
    JCO Precis Oncol, 7, e2300440
    DOI 10.1200/PO.23.00440, PubMed 37897815
  37. Davies EM, Mitchell CA, Stenmark HA (2023)
    Phosphoinositides in New Spaces
    Cold Spring Harb Perspect Biol, 15 (9)
    DOI 10.1101/cshperspect.a041406, PubMed 37463718
  38. Skingen VE, Hompland T, Fjeldbo CS, Salberg UB, Helgeland H, Ragnum HB, Aarnes EK, Vlatkovic L, Hole KH, Seierstad T, Lyng H (2023)
    Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels
    Radiother Oncol, 188, 109875
    DOI 10.1016/j.radonc.2023.109875, PubMed 37640161
  39. Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H (2023)
    The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
    iScience, 26 (10), 107726
    DOI 10.1016/j.isci.2023.107726, PubMed 37720104
  40. Foldvari Z, Knetter C, Yang W, Gjerdingen TJ, Bollineni RC, Tran TT, Lund-Johansen F, Kolstad A, Drousch K, Klopfleisch R, Leisegang M, Olweus J (2023)
    A systematic safety pipeline for selection of T-cell receptors to enter clinical use
    NPJ Vaccines, 8 (1), 126
    DOI 10.1038/s41541-023-00713-y, PubMed 37607971
  41. Philippon C, Tao S, Clement D, Haroun-Izquierdo A, Kichula KM, Netskar H, Brandt L, Oei VS, Kanaya M, Lanuza PM, Schaffer M, Goodridge JP, Horowitz A, Zhu F, Hammer Q, Sohlberg E, Majhi RK, Kveberg L, Önfelt B, Norman PJ, Malmberg KJ (2023)
    Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires
    Blood Adv, 7 (16), 4492-4504
    DOI 10.1182/bloodadvances.2023009827, PubMed 37327114
  42. Kvassheim M, Tornes AJK, Juzeniene A, Stokke C, Revheim MR (2023)
    Imaging of 212Pb in mice with a clinical SPECT/CT
    EJNMMI Phys, 10 (1), 47
    DOI 10.1186/s40658-023-00571-6, PubMed 37603123
  43. Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML (2023)
    Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
    Biophys J (in press)
    DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785
  44. Akdeniz BC, Mattingsdal M, Dominguez-Valentin M, Frei O, Shadrin A, Puustusmaa M, Saar R, Sõber S, Møller P, Andreassen OA, Padrik P, Hovig E (2023)
    A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
    Cancers (Basel), 15 (16)
    DOI 10.3390/cancers15164124, PubMed 37627152
  45. Ellingsen EB, O'Day S, Mezheyeuski A, Gromadka A, Clancy T, Kristedja TS, Milhem M, Zakharia Y (2023)
    Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
    Clin Cancer Res, 29 (16), 3026-3036
    DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
  46. Solbakken AM, Flatmark K (2023)
    ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
    Ann Surg Oncol, 30 (12), 7633-7634
    DOI 10.1245/s10434-023-14058-2, PubMed 37573284
  47. Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
    Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
    BMC Res Notes, 16 (1), 167
    DOI 10.1186/s13104-023-06437-5, PubMed 37568187
  48. Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
    Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
    Int J Cancer, 153 (10), 1819-1828
    DOI 10.1002/ijc.34666, PubMed 37551617
  49. Le Tourneau C, André F, Helland Å, Mileshkin L, Minnaard W, Schiel A, Taskén K, Thomas DM, Veronese ML, Durán-Pacheco G, Leyens L, Rufibach K, Thomas M, Krämer A (2023)
    Modified study designs to expand treatment options in personalised oncology: a multistakeholder view
    Eur J Cancer, 194, 113278
    DOI 10.1016/j.ejca.2023.113278, PubMed 37820553
  50. Sarmento MJ, Llorente A, Petan T, Khnykin D, Popa I, Nikolac Perkovic M, Konjevod M, Jaganjac M (2023)
    The expanding organelle lipidomes: current knowledge and challenges
    Cell Mol Life Sci, 80 (8), 237
    DOI 10.1007/s00018-023-04889-3, PubMed 37530856
  51. Skotland T, Llorente A, Sandvig K (2023)
    Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?
    Cold Spring Harb Perspect Biol, 15 (8)
    DOI 10.1101/cshperspect.a041415, PubMed 37277192
  52. Torices L, Nunes-Xavier CE, López JI, Pulido R (2023)
    Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants
    PLoS One, 18 (8), e0289369
    DOI 10.1371/journal.pone.0289369, PubMed 37527256
  53. Zhen Y, Stenmark H (2023)
    A phosphoinositide kinase triggers migrasome formation
    Cell Res, 33 (8), 577-578
    DOI 10.1038/s41422-023-00822-2, PubMed 37165066
  54. Pust S, Brech A, Wegner CS, Stenmark H, Haglund K (2023)
    Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
    Cell Mol Life Sci, 80 (8), 235
    DOI 10.1007/s00018-023-04864-y, PubMed 37523003
  55. Bogaard M, Skotheim RI, Maltau AV, Kidd SG, Lothe RA, Axcrona K, Axcrona U (2023)
    'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
    Histopathology, 83 (6), 853-869
    DOI 10.1111/his.15012, PubMed 37501635
  56. Denisova OV, Merisaari J, Huhtaniemi R, Qiao X, Yetukuri L, Jumppanen M, Kaur A, Pääkkönen M, von Schantz-Fant С, Ohlmeyer M, Wennerberg K, Kauko O, Koch R, Aittokallio T, Taipale M, Westermarck J (2023)
    PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
    Mol Oncol, 17 (9), 1803-1820
    DOI 10.1002/1878-0261.13488, PubMed 37458534
  57. Solbakken AM, Sellevold S, Spasojevic M, Julsrud L, Emblemsvåg HL, Reims HM, Sørensen O, Thorgersen EB, Fauske L, Ågren JSM, Brennhovd B, Ryder T, Larsen SG, Flatmark K (2023)
    Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
    Ann Surg Oncol, 30 (12), 7602-7611
    DOI 10.1245/s10434-023-13964-9, PubMed 37481493
  58. Nguyen HL, Geukens T, Maetens M, Aparicio S, Bassez A, Borg A, Brock J, Broeks A, Caldas C, Cardoso F, De Schepper M, Delorenzi M, Drukker CA, Glas AM, Green AR, Isnaldi E, Eyfjörð J, Khout H, Knappskog S, Krishnamurthy S, Lakhani SR, Langerod A, Martens JWM, McCart Reed AE, Murphy L et al. (2023)
    Obesity-associated changes in molecular biology of primary breast cancer
    Nat Commun, 14 (1), 4418
    DOI 10.1038/s41467-023-39996-z, PubMed 37479706
  59. Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C (2023)
    Protrudin-mediated ER-endosome contact sites promote phagocytosis
    Cell Mol Life Sci, 80 (8), 216
    DOI 10.1007/s00018-023-04862-0, PubMed 37468729
  60. Kalyanasundaram S, Lefol Y, Gundersen S, Rognes T, Alsøe L, Nilsen HL, Hovig E, Sandve GK, Domanska D (2023)
    hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
    PLoS One, 18 (7), e0286330
    DOI 10.1371/journal.pone.0286330, PubMed 37467208
  61. Tamargo-Gómez I, Martínez-García GG, Suárez MF, Mayoral P, Bretones G, Astudillo A, Prieto-Lloret J, Sveen C, Fueyo A, Engedal N, López-Otín C, Mariño G (2023)
    Analysis of ATG4C function in vivo
    Autophagy, 19 (11), 2912-2933
    DOI 10.1080/15548627.2023.2234799, PubMed 37459465
  62. Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
    Endocytic trafficking of connexins in cancer pathogenesis
    Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
    DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772
  63. Wang MM, Coupland SE, Aittokallio T, Figueiredo CR (2023)
    Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities
    Br J Cancer, 129 (8), 1212-1224
    DOI 10.1038/s41416-023-02361-4, PubMed 37454231
  64. van Amerongen R, Bentires-Alj M, van Boxtel AL, Clarke RB, Fre S, Suarez EG, Iggo R, Jechlinger M, Jonkers J, Mikkola ML, Koledova ZS, Sørlie T, Vivanco MD (2023)
    Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
    J Mammary Gland Biol Neoplasia, 28 (1), 17
    DOI 10.1007/s10911-023-09544-y, PubMed 37450065
  65. Nähse V, Raiborg C, Tan KW, Mørk S, Torgersen ML, Wenzel EM, Nager M, Salo VT, Johansen T, Ikonen E, Schink KO, Stenmark H (2023)
    ATPase activity of DFCP1 controls selective autophagy
    Nat Commun, 14 (1), 4051
    DOI 10.1038/s41467-023-39641-9, PubMed 37422481
  66. Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
    TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
    EMBO J, 42 (17), e113105
    DOI 10.15252/embj.2022113105, PubMed 37409525
  67. Langberg CW, Horndalsveen H, Helland Å, Haakensen VD (2023)
    Factors associated with failure to start consolidation durvalumab after definitive chemoradiation for locally advanced NSCLC
    Front Oncol, 13, 1217424
    DOI 10.3389/fonc.2023.1217424, PubMed 37476372
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  131. Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
    Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
    Proc Natl Acad Sci U S A, 120 (6), e2211368120
    DOI 10.1073/pnas.2211368120, PubMed 36730202
  132. Meier Strømme J, Johannessen B, Skotheim RI (2023)
    Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer
    JCO Clin Cancer Inform, 7, e2200159
    DOI 10.1200/CCI.22.00159, PubMed 36821799
  133. Odabasi E, Conkar D, Deretic J, Batman U, Frikstad KM, Patzke S, Firat-Karalar EN (2023)
    CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins
    J Cell Sci, 136 (3)
    DOI 10.1242/jcs.260327, PubMed 36606424
  134. Sagini K, Urbanelli L, Buratta S, Emiliani C, Llorente A (2023)
    Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
    Pharmaceutics, 15 (2)
    DOI 10.3390/pharmaceutics15020437, PubMed 36839759
  135. Nunzi E, Mezzasoma L, Bellezza I, Zelante T, Orvietani P, Coata G, Giardina I, Sagini K, Manni G, Di Michele A, Gargaro M, Talesa VN, Di Renzo GC, Fallarino F, Romani R (2023)
    Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
    Int J Mol Sci, 24 (3)
    DOI 10.3390/ijms24032527, PubMed 36768851
  136. Normann LS, Haugen MH, Hongisto V, Aure MR, Leivonen SK, Kristensen VN, Tahiri A, Engebraaten O, Sahlberg KK, Mælandsmo GM (2023)
    High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
    PLoS One, 18 (1), e0280507
    DOI 10.1371/journal.pone.0280507, PubMed 36706086
  137. Doutel D, Davidson B, Nitschke Pettersen IK, Torgunrud A (2023)
    Molecular characteristics of low-grade serous carcinoma in effusions
    Cytopathology, 34 (2), 99-105
    DOI 10.1111/cyt.13207, PubMed 36609991
  138. Vitelli V, Fleischer T, Ankill J, Arjas E, Frigessi A, Kristensen VN, Zucknick M (2023)
    Transcriptomic pan-cancer analysis using rank-based Bayesian inference
    Mol Oncol, 17 (4), 548-563
    DOI 10.1002/1878-0261.13354, PubMed 36562628
  139. Daniel P, Balušíková K, Václavíková R, Šeborová K, Ransdorfová Š, Valeriánová M, Wei L, Jelínek M, Tlapáková T, Fleischer T, Kristensen VN, Souček P, Ojima I, Kovář J (2023)
    ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines
    Genes (Basel), 14 (2)
    DOI 10.3390/genes14020296, PubMed 36833223
  140. Skoie IM, Skogås JG, Langø T, Myhr KM, Myhre PL, Goll R, Fretland SØ, Helland Å (2023)
    New centres to carry out more clinical trials in Norway
    Tidsskr Nor Laegeforen, 143 (2)
    DOI 10.4045/tidsskr.22.0722, PubMed 36718905
  141. Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, Chandrasekar C, Schiffman JD, Brohl AS, James PA, Kurtz JE, Penel N, Myklebost O, Meza-Zepeda LA, Pickett H, Kansara M et al. (2023)
    Heritable defects in telomere and mitotic function selectively predispose to sarcomas
    Science, 379 (6629), 253-260
    DOI 10.1126/science.abj4784, PubMed 36656928
  142. Ramos-Alonso L, Holland P, Le Gras S, Zhao X, Jost B, Bjørås M, Barral Y, Enserink JM, Chymkowitch P (2023)
    Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
    Proc Natl Acad Sci U S A, 120 (4), e2210593120
    DOI 10.1073/pnas.2210593120, PubMed 36656860
  143. Juzeniene A, Stenberg VY, Bruland ØS, Revheim ME, Larsen RH (2023)
    Dual targeting with 224Ra/212Pb-conjugates for targeted alpha therapy of disseminated cancers: A conceptual approach
    Front Med (Lausanne), 9, 1051825
    DOI 10.3389/fmed.2022.1051825, PubMed 36733936
  144. Johanssen T, McVeigh L, Erridge S, Higgins G, Straehla J, Frame M, Aittokallio T, Carragher NO, Ebner D (2023)
    Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia
    Front Oncol, 12, 1075559
    DOI 10.3389/fonc.2022.1075559, PubMed 36733367
  145. Ellingsen EB, Bjørheim J, Gaudernack G (2023)
    Therapeutic cancer vaccination against telomerase: clinical developments in melanoma
    Curr Opin Oncol, 35 (2), 100-106
    DOI 10.1097/CCO.0000000000000922, PubMed 36700456
  146. Hyldbakk A, Fleten KG, Snipstad S, Åslund AKO, Davies CL, Flatmark K, Mørch Y (2023)
    Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
    Nanomedicine, 48, 102656
    DOI 10.1016/j.nano.2023.102656, PubMed 36646195
  147. Panagiotakis S, Mavroidi B, Athanasopoulos A, Gonçalves AR, Bugnicourt-Moreira L, Regagnon T, Boukos N, Charalambidis G, Coutsolelos AG, Grigalavicius M, Theodossiou TA, Berg K, Ladavière C, Pelecanou M, Yannakopoulou K (2023)
    Small anticancer drug release by light: Photochemical internalization of porphyrin-β-cyclodextrin nanoparticles
    Carbohydr Polym, 306, 120579
    DOI 10.1016/j.carbpol.2023.120579, PubMed 36746578
  148. Shah UA, Whiting K, Devlin S, Ershler R, Kanapuru B, Lee DJ, Tahri S, Gwise T, Rustad EH, Mailankody S, Lesokhin AM, Kazandjian D, Maura F, Auclair D, Birmann BM, Usmani SZ, Gormley N, Marinac CR, Landgren O (2023)
    Extreme body mass index and survival in newly diagnosed multiple myeloma patients
    Blood Cancer J, 13 (1), 13
    DOI 10.1038/s41408-022-00782-7, PubMed 36631444
  149. Kamijo K, Shimomura Y, Shinohara A, Mizuno S, Kanaya M, Usui Y, Kim SW, Ara T, Mizuno I, Kuriyama T, Nakazawa H, Matsuoka KI, Kusumoto S, Maseki N, Yamaguchi M, Ashida T, Onizuka M, Fukuda T, Atsuta Y, Kondo E (2023)
    Fludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation
    Ann Hematol, 102 (3), 651-661
    DOI 10.1007/s00277-023-05084-x, PubMed 36631705
  150. Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai KZ, Madssen TS, Vaage JT, Gustavsen A, Yang W, Nissen-Meyer LSH, Douvlataniotis K, Laos M, Nielsen MM, Thiede B, Søraas A, Lund-Johansen F, Rustad EH, Olweus J (2023)
    Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
    Cell Rep, 42 (1), 111995
    DOI 10.1016/j.celrep.2023.111995, PubMed 36656713
  151. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 115
    DOI 10.1038/s41467-022-35624-4, PubMed 36611026
  152. Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
    The genetic history of Scandinavia from the Roman Iron Age to the present
    Cell, 186 (1), 32-46.e19
    DOI 10.1016/j.cell.2022.11.024, PubMed 36608656
  153. Pulido R, Nunes-Xavier CE (2023)
    Editorial: Cell and Developmental Signalling in Neuroblastoma
    Front Cell Dev Biol, 10, 1126352
    DOI 10.3389/fcell.2022.1126352, PubMed 36684434
  154. Chojnacka M, Diamond B, Ziccheddu B, Rustad E, Maclachlan K, Papadimitriou M, Boyle EM, Blaney P, Usmani S, Morgan G, Landgren O, Maura F (2023)
    Impact of rare structural variant events in newly diagnosed multiple myeloma
    bioRxiv
    DOI 10.1101/2023.01.03.522573, PubMed 36711679
  155. Leech M, Leijenaar RTH, Hompland T, Gaffney J, Lyng H, Marignol L (2023)
    Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring
    Anticancer Res, 43 (1), 351-357
    DOI 10.21873/anticanres.16170, PubMed 36585179
  156. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
  157. Skånland SS, Brown JR (2023)
    PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
    Haematologica, 108 (1), 9-21
    DOI 10.3324/haematol.2022.281266, PubMed 35899388
  158. Levy-Jurgenson A, Tekpli X, Kristensen VN, Yakhini Z (2023)
    Analysis of Spatial Molecular Data
    Methods Mol Biol, 2614, 349-356
    DOI 10.1007/978-1-0716-2914-7_20, PubMed 36587134
  159. Wind A, Oberst S, Westerhuis W, Blaauwgeers H, Sæter G, de Paoli P, Nagy P, Burrion JB, Jolly E, Lovey J, van Harten W (2023)
    Evaluating comprehensive cancer networks; a review of standards and evaluation methods for care networks to inform a comparison with the OECI comprehensive cancer network standards
    Acta Oncol, 62 (1), 15-24
    DOI 10.1080/0284186X.2023.2170275, PubMed 36786345
  160. Robsahm TE, Tsuruda KM, Hektoen HH, Storås AH, Cook MB, Hurwitz LM, Langseth H (2023)
    Applying recommended definition of aggressive prostate cancer: a validation study using high-quality data from the Cancer Registry of Norway
    Acta Oncol, 62 (1), 8-14
    DOI 10.1080/0284186X.2023.2175331, PubMed 36762472
  161. Jeanmougin M, Brodal HP, Dietrichson Pharo H, Vedeld HM, Lind GE (2023)
    PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac766, PubMed 36448696

Publications 2022

  1. Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
    T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
    Gigascience, 12
    DOI 10.1093/gigascience/giad032, PubMed 37161965
  2. Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA (2022)
    The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
    Cancer, 129 (6), 901-907
    DOI 10.1002/cncr.34615, PubMed 36571512
  3. Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
    Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
    Front Cell Dev Biol, 10, 1022191
    DOI 10.3389/fcell.2022.1022191, PubMed 36619857
  4. Torices L, Mingo J, Rodríguez-Escudero I, Fernández-Acero T, Luna S, Nunes-Xavier CE, López JI, Mercadillo F, Currás M, Urioste M, Molina M, Cid VJ, Pulido R (2022)
    Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
    Eur J Hum Genet, 31 (5), 568-577
    DOI 10.1038/s41431-022-01265-w, PubMed 36543932
  5. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A et al. (2022)
    Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
    Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
    DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
  6. Vaccaro CA, Soarez J, Dominguez-Valentin M, Pavicic WH (2022)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
    Front Oncol, 12, 1104671
    DOI 10.3389/fonc.2022.1104671, PubMed 36601476
  7. Lyng H, Skipar K, Hompland T (2022)
    Targeted Therapy on the Screen: Do We Hit the Target?
    Clin Cancer Res, 28 (24), 5233-5234
    DOI 10.1158/1078-0432.CCR-22-2707, PubMed 36240006
  8. Kuźniewska A, Thiel M, Kowalska D, Felberg-Miętka A, Szynkowski P, Ołdziej S, Arjona E, Jongerius I, Rodriguez de Córdoba S, Okrój M, Urban A (2022)
    Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein
    Front Immunol, 13, 1061696
    DOI 10.3389/fimmu.2022.1061696, PubMed 36591303
  9. Sinno N, Taylor E, Hompland T, Milosevic M, Jaffray DA, Coolens C (2022)
    Incorporating cross-voxel exchange for the analysis of dynamic contrast-enhanced imaging data: pre-clinical results
    Phys Med Biol, 67 (24)
    DOI 10.1088/1361-6560/aca512, PubMed 36541560
  10. Charsou C, Ng MYW, Simonsen A (2022)
    Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
    Autophagy, 19 (7), 2159-2161
    DOI 10.1080/15548627.2022.2155020, PubMed 36469687
  11. Gulati G, Tjessem KH, Horndalsveen H, Halvorsen S, Haakensen VD (2022)
    [Checkpoint inhibitor-induced myocarditis]
    Tidsskr Nor Laegeforen, 142 (18)
    DOI 10.4045/tidsskr.21.0817, PubMed 36511752
  12. Hugosson J, Månsson M, Wallström J, Axcrona U, Carlsson SV, Egevad L, Geterud K, Khatami A, Kohestani K, Pihl CG, Socratous A, Stranne J, Godtman RA, Hellström M, GÖTEBORG-2 Trial Investigators (2022)
    Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only
    N Engl J Med, 387 (23), 2126-2137
    DOI 10.1056/NEJMoa2209454, PubMed 36477032
  13. Murumägi A, Ungureanu D, Khan S, Arjama M, Välimäki K, Ianevski A, Ianevski P, Bergström R, Dini A, Kanerva A, Koivisto-Korander R, Tapper J, Lassus H, Loukovaara M, Mägi A, Hirasawa A, Aoki D, Pietiäinen V, Pellinen T, Bützow R, Aittokallio T, Kallioniemi O (2022)
    Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma
    Br J Cancer, 128 (4), 678-690
    DOI 10.1038/s41416-022-02067-z, PubMed 36476658
  14. Stacchiotti S, Dürr HR, Schaefer IM, Woertler K, Haas R, Trama A, Caraceni A, Bajpai J, Baldi GG, Bernthal N, Blay JY, Boye K, Broto JM, Chen WT, Dei Tos PA, Desai J, Emhofer S, Eriksson M, Gronchi A, Gelderblom H, Hardes J, Hartmann W, Healey J, Italiano A, Jones RL et al. (2022)
    Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts
    Cancer Treat Rev, 112, 102491
    DOI 10.1016/j.ctrv.2022.102491, PubMed 36502615
  15. Chen J, Song Y, Li Y, Wei Y, Shen S, Zhao Y, You D, Su L, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Shen H, Christiani DC, Zhang R, Chen F (2022)
    A trans-omics assessment of gene-gene interaction in early-stage NSCLC
    Mol Oncol, 17 (1), 173-187
    DOI 10.1002/1878-0261.13345, PubMed 36408734
  16. Seborova K, Hlavac V, Holy P, Bjørklund SS, Fleischer T, Rob L, Hruda M, Bouda J, Mrhalova M, Allah MMKAO, Vodicka P, Fiala O, Soucek P, Kristensen VN, Vodickova L, Vaclavikova R (2022)
    Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy
    Front Oncol, 12, 1016958
    DOI 10.3389/fonc.2022.1016958, PubMed 36531044
  17. Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD et al. (2022)
    Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
    Cancer Discov, 12 (12), 2930-2953
    DOI 10.1158/2159-8290.CD-21-0865, PubMed 36108220
  18. Ganley IG, Simonsen A (2022)
    Diversity of mitophagy pathways at a glance
    J Cell Sci, 135 (23)
    DOI 10.1242/jcs.259748, PubMed 36504076
  19. Axcrona K, Aas K, Axcrona U, Skotheim RI (2022)
    Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
    Eur Urol, 83 (2), 183
    DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529
  20. Røssevold AH, Andresen NK, Bjerre CA, Gilje B, Jakobsen EH, Raj SX, Falk RS, Russnes HG, Jahr T, Mathiesen RR, Lømo J, Garred Ø, Chauhan SK, Lereim RR, Dunn C, Naume B, Kyte JA (2022)
    Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
    Nat Med, 28 (12), 2573-2583
    DOI 10.1038/s41591-022-02126-1, PubMed 36482103
  21. Børø S, Thoresen S, Helland Å (2022)
    Improvements in survival for patients with stage IV adenocarcinoma in the lung, diagnosed between 2010 - 2020 - A population-based registry study from Norway
    Front Oncol, 12, 1017902
    DOI 10.3389/fonc.2022.1017902, PubMed 36523970
  22. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
    DOI 10.3389/fonc.2022.1040730, PubMed 36523963
  23. Cichocki F, Bjordahl R, Goodridge JP, Mahmood S, Gaidarova S, Abujarour R, Davis ZB, Merino A, Tuininga K, Wang H, Kumar A, Groff B, Witty A, Bonello G, Huffman J, Dailey T, Lee TT, Malmberg KJ, Walcheck B, Höpken U, Rehm A, Valamehr B, Miller JS (2022)
    Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
    Nat Commun, 13 (1), 7341
    DOI 10.1038/s41467-022-35127-2, PubMed 36446823
  24. Castro-Mondragon JA, Aure MR, Lingjærde OC, Langerød A, Martens JWM, Børresen-Dale AL, Kristensen VN, Mathelier A (2022)
    Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
    Nucleic Acids Res, 50 (21), 12131-12148
    DOI 10.1093/nar/gkac1143, PubMed 36477895
  25. Fleten KG, Hyldbakk A, Einen C, Benjakul S, Strand BL, Davies CL, Mørch Ý, Flatmark K (2022)
    Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
    Mar Drugs, 20 (12)
    DOI 10.3390/md20120744, PubMed 36547891
  26. Nunes-Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Taskén KA, Mælandsmo GM, Fodstad Ø, Llarena R, Pulido R, López JI (2022)
    Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
    Pathol Res Pract, 241, 154243
    DOI 10.1016/j.prp.2022.154243, PubMed 36481650
  27. Tornes AJK, Stenberg VY, Larsen RH, Bruland ØS, Revheim ME, Juzeniene A (2022)
    Targeted alpha therapy with the 224Ra/212Pb-TCMC-TP-3 dual alpha solution in a multicellular tumor spheroid model of osteosarcoma
    Front Med (Lausanne), 9, 1058863
    DOI 10.3389/fmed.2022.1058863, PubMed 36507500
  28. Horndalsveen H, Alver TN, Dalsgaard AM, Rogg LV, Helbekkmo N, Grønberg BH, Halvorsen TO, Ramberg C, Haakensen VD, Öjlert ÅK, Bjaanaes MM, Helland Å (2022)
    Atezolizumab and stereotactic body radiotherapy in patients with advanced non-small cell lung cancer: safety, clinical activity and ctDNA responses-the ComIT-1 trial
    Mol Oncol, 17 (3), 487-498
    DOI 10.1002/1878-0261.13330, PubMed 36330681
  29. Møller P (2022)
    The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
    Hered Cancer Clin Pract, 20 (1), 37
    DOI 10.1186/s13053-022-00243-z, PubMed 36411472
  30. Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
    Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
    EMBO J, 41 (24), e112677
    DOI 10.15252/embj.2022112677, PubMed 36408828
  31. Yri OE, Aass N, Kaasa S (2022)
    [Whole brain radiotherapy should be restricted]
    Tidsskr Nor Laegeforen, 142 (17)
    DOI 10.4045/tidsskr.22.0696, PubMed 36416654
  32. Ravindran V, Wagoner J, Athanasiadis P, Den Hartigh AB, Sidorova JM, Ianevski A, Fink SL, Frigessi A, White J, Polyak SJ, Aittokallio T (2022)
    Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network
    Brief Bioinform, 23 (6)
    DOI 10.1093/bib/bbac456, PubMed 36305426
  33. Huse K, Bai B, Hilden VI, Bollum LK, Våtsveen TK, Munthe LA, Smeland EB, Irish JM, Wälchli S, Myklebust JH (2022)
    Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression
    J Immunol, 209 (10), 2042-2053
    DOI 10.4049/jimmunol.2200144, PubMed 36426942
  34. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
    Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
    Cancers (Basel), 14 (22)
    DOI 10.3390/cancers14225603, PubMed 36428697
  35. Stanciu SG, Hristu R, Stanciu GA, Tranca DE, Eftimie L, Dumitru A, Costache M, Stenmark HA, Manders H, Cherian A, Tark-Dame M, Manders EMM (2022)
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  162. Riise J, Meyer S, Blaas I, Chopra A, Tran TT, Delic-Sarac M, Hestdalen ML, Brodin E, Rustad EH, Dai KZ, Vaage JT, Nissen-Meyer LSH, Sund F, Wader KF, Bjornevik AT, Meyer PA, Nygaard GO, König M, Smeland S, Lund-Johansen F, Olweus J, Kolstad A (2022)
    Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
    Br J Haematol, 197 (6), 697-708
    DOI 10.1111/bjh.18149, PubMed 35254660
  163. Frikstad KM, Schink KO, Gilani S, Pedersen LB, Patzke S (2022)
    3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
    Bio Protoc, 12 (6), e4360
    DOI 10.21769/BioProtoc.4360, PubMed 35434191
  164. Skotland T, Sandvig K (2022)
    Need for more focus on lipid species in studies of biological and model membranes
    Prog Lipid Res, 86, 101160
    DOI 10.1016/j.plipres.2022.101160, PubMed 35288150
  165. Ianevski A, Giri AK, Aittokallio T (2022)
    Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data
    Nat Commun, 13 (1), 1246
    DOI 10.1038/s41467-022-28803-w, PubMed 35273156
  166. Bollineni RC, Tran TT, Lund-Johansen F, Olweus J (2022)
    Chasing neoantigens; invite naïve T cells to the party
    Curr Opin Immunol, 75, 102172
    DOI 10.1016/j.coi.2022.102172, PubMed 35279483
  167. Aittokallio T (2022)
    What are the current challenges for machine learning in drug discovery and repurposing?
    Expert Opin Drug Discov, 17 (5), 423-425
    DOI 10.1080/17460441.2022.2050694, PubMed 35255749
  168. Gorunova L, Boye K, Panagopoulos I, Berner JM, Bjerkehagen B, Hompland I, Lobmaier I, Hølmebakk T, Hveem TS, Heim S, Micci F (2022)
    Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
    Oncotarget, 13, 508-517
    DOI 10.18632/oncotarget.28209, PubMed 35284037
  169. Mo T, Brandal SHB, Köhn-Luque A, Engebraaten O, Kristensen VN, Fleischer T, Hompland T, Seierstad T (2022)
    Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
    Cancers (Basel), 14 (5)
    DOI 10.3390/cancers14051326, PubMed 35267636
  170. Migliano SM, Wenzel EM, Stenmark H (2022)
    Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
    Curr Opin Cell Biol, 75, 102062
    DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976
  171. Ramos-Alonso L, Garcia I, Enserink JM, Chymkowitch P (2022)
    Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
    STAR Protoc, 3 (1), 101210
    DOI 10.1016/j.xpro.2022.101210, PubMed 35265859
  172. Ali M, Fulci G, Grigalavicius M, Pulli B, Li A, Wojtkiewicz GR, Wang C, Hsieh KL, Linnoila JJ, Theodossiou TA, Chen JW (2022)
    Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy
    Neoplasia, 26, 100779
    DOI 10.1016/j.neo.2022.100779, PubMed 35247801
  173. Normann LS, Haugen MH, Aure MR, Kristensen VN, Mælandsmo GM, Sahlberg KK (2022)
    miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
    Breast Cancer (Dove Med Press), 14, 25-39
    DOI 10.2147/BCTT.S338404, PubMed 35256859
  174. Pataskar A, Champagne J, Nagel R, Kenski J, Laos M, Michaux J, Pak HS, Bleijerveld OB, Mordente K, Navarro JM, Blommaert N, Nielsen MM, Lovecchio D, Stone E, Georgiou G, de Gooijer MC, van Tellingen O, Altelaar M, Joosten RP, Perrakis A, Olweus J, Bassani-Sternberg M, Peeper DS, Agami R (2022)
    Tryptophan depletion results in tryptophan-to-phenylalanine substitutants
    Nature, 603 (7902), 721-727
    DOI 10.1038/s41586-022-04499-2, PubMed 35264796
  175. Giliberto M, Thimiri Govinda Raj DB, Cremaschi A, Skånland SS, Gade A, Tjønnfjord GE, Schjesvold F, Munthe LA, Taskén K (2022)
    Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
    Mol Oncol, 16 (6), 1241-1258
    DOI 10.1002/1878-0261.13191, PubMed 35148457
  176. Simonsen A, Wollert T (2022)
    Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
    Curr Opin Cell Biol, 75, 102064
    DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373
  177. Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
    Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Autophagy, 18 (11), 2547-2560
    DOI 10.1080/15548627.2022.2039535, PubMed 35220892
  178. Hodan R, Rodgers-Fouche L, Arora S, Dominguez-Valentin M, Kanth P, Katona BW, Mraz KA, Roberts ME, Vilar E, Soto-Azghani CM, Brand RE, Esplin ED, Perez K (2022)
    Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    J Genet Couns, 31 (4), 949-955
    DOI 10.1002/jgc4.1567, PubMed 35218578
  179. Dominguez-Valentin M, Sampson JR, Seppälä TT, Møller P (2022)
    Response to Chambuso et al
    Genet Med, 24 (5), 1151
    DOI 10.1016/j.gim.2022.01.005, PubMed 35216900
  180. Strømme JM, Johannessen B, Kidd SG, Bogaard M, Carm KT, Zhang X, Sveen A, Mathelier A, Lothe RA, Axcrona U, Axcrona K, Skotheim RI (2022)
    Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
    Cancer Gene Ther, 29 (8-9), 1276-1284
    DOI 10.1038/s41417-022-00444-7, PubMed 35194199
  181. Fontugne J, Cai PY, Alnajar H, Bhinder B, Park K, Ye H, Beg S, Sailer V, Siddiqui J, Blattner-Johnson M, Croyle JA, Noorzad Z, Calagua C, MacDonald TY, Axcrona U, Bogaard M, Axcrona K, Scherr DS, Sanda MG, Johannessen B, Chinnaiyan AM, Elemento O, Skotheim RI, Rubin MA, Barbieri CE et al. (2022)
    Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
    JCI Insight, 7 (4)
    DOI 10.1172/jci.insight.155309, PubMed 35050902
  182. Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
    Waves of sumoylation support transcription dynamics during adipocyte differentiation
    Nucleic Acids Res, 50 (3), 1351-1369
    DOI 10.1093/nar/gkac027, PubMed 35100417
  183. Hammer Q, Dunst J, Christ W, Picarazzi F, Wendorff M, Momayyezi P, Huhn O, Netskar HK, Maleki KT, García M, Sekine T, Sohlberg E, Azzimato V, Aouadi M, Karolinska COVID-19 Study Group, Severe COVID-19 GWAS Group, Degenhardt F, Franke A, Spallotta F, Mori M, Michaëlsson J, Björkström NK, Rückert T, Romagnani C, Horowitz A et al. (2022)
    SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
    Cell Rep, 38 (10), 110503
    DOI 10.1016/j.celrep.2022.110503, PubMed 35235832
  184. Engedal N, Proikas-Cezanne T, Albertini MC, Žerovnik E, Lane JD (2022)
    Transautophagy: Research and Translation of Autophagy Knowledge 2020
    Oxid Med Cell Longev, 2022, 9792132
    DOI 10.1155/2022/9792132, PubMed 35340207
  185. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
    miR-486-5p expression is regulated by DNA methylation in osteosarcoma
    BMC Genomics, 23 (1), 142
    DOI 10.1186/s12864-022-08346-6, PubMed 35172717
  186. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
    Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
    J Infect Dis, 225 (4), 661-674
    DOI 10.1093/infdis/jiaa714, PubMed 33216130
  187. Nilsen A, Hillestad T, Skingen VE, Aarnes EK, Fjeldbo CS, Hompland T, Evensen TS, Stokke T, Kristensen GB, Grallert B, Lyng H (2022)
    miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
    Mol Oncol, 16 (6), 1402-1419
    DOI 10.1002/1878-0261.13184, PubMed 35064630
  188. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  189. Mateus D, Wiedlocha A (2022)
    FGF-FGFR signaling promotes the development of invasive cervical cancer
    FEBS J, 289 (12), 3419-3421
    DOI 10.1111/febs.16384, PubMed 35146913
  190. Umu SU, Langseth H, Zuber V, Helland Å, Lyle R, Rounge TB (2022)
    Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
    Elife, 11
    DOI 10.7554/eLife.71035, PubMed 35147498
  191. Møller P, Evans DG (2022)
    Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030879, PubMed 35160330
  192. Holland P, Quintana EM, Khezri R, Schoborg TA, Rusten TE (2022)
    Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
    Sci Rep, 12 (1), 2056
    DOI 10.1038/s41598-022-05991-5, PubMed 35136137
  193. Blijdorp CJ, Burger D, Llorente A, Martens-Uzunova ES, Erdbrügger U (2022)
    Extracellular Vesicles as Novel Players in Kidney Disease
    J Am Soc Nephrol, 33 (3), 467-471
    DOI 10.1681/ASN.2021091232, PubMed 35131841
  194. Nissen-Meyer J, Skotland T, Boye E (2022)
    Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
    EMBO Rep, 23 (3), e54431
    DOI 10.15252/embr.202154431, PubMed 35156749
  195. Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ (2022)
    Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
    Blood, 139 (5), 704-716
    DOI 10.1182/blood.2021013233, PubMed 34699594
  196. Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M (2022)
    Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
    Cells, 11 (3)
    DOI 10.3390/cells11030522, PubMed 35159330
  197. Enserink JM, Chymkowitch P (2022)
    Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
    Int J Mol Sci, 23 (3)
    DOI 10.3390/ijms23031293, PubMed 35163213
  198. Kyte JA (2022)
    Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers
    Cancers (Basel), 14 (3)
    DOI 10.3390/cancers14030571, PubMed 35158839
  199. Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q (2022)
    Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
    Biomedicines, 10 (2)
    DOI 10.3390/biomedicines10020232, PubMed 35203441
  200. Xia YY, Gronwald J, Karlan B, Lubinski J, McCuaig JM, Brooks J, Moller P, Eisen A, Sun S, Senter L, Bordeleau L, Neuhausen SL, Singer CF, Tung N, Foulkes WD, Sun P, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2022)
    Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 164 (3), 514-521
    DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280
  201. Ballester PJ, Stevens R, Haibe-Kains B, Huang RS, Aittokallio T (2022)
    Artificial intelligence for drug response prediction in disease models
    Brief Bioinform, 23 (1)
    DOI 10.1093/bib/bbab450, PubMed 34655289
  202. Wolf J, Helland Å, Oh IJ, Migliorino MR, Dziadziuszko R, Wrona A, de Castro J, Mazieres J, Griesinger F, Chlistalla M, Cardona A, Ruf T, Trunzer K, Smoljanovic V, Novello S (2022)
    Final efficacy and safety data, and exploratory molecular profiling from the phase III ALUR study of alectinib versus chemotherapy in crizotinib-pretreated ALK-positive non-small-cell lung cancer
    ESMO Open, 7 (1), 100333
    DOI 10.1016/j.esmoop.2021.100333, PubMed 35042152
  203. Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
    STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
    Am J Cancer Res, 12 (1), 327-336
    PubMed 35141021
  204. Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
    A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
    NAR Cancer, 4 (1), zcab051
    DOI 10.1093/narcan/zcab051, PubMed 35047825
  205. Alaña L, Nunes-Xavier CE, Zaldumbide L, Martin-Guerrero I, Mosteiro L, Alba-Pavón P, Villate O, García-Obregón S, González-García H, Herraiz R, Astigarraga I, Pulido R, García-Ariza M (2022)
    Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
    Cancers (Basel), 14 (2)
    DOI 10.3390/cancers14020421, PubMed 35053583
  206. Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M (2022)
    HLA-independent T cell receptors for targeting tumors with low antigen density
    Nat Med, 28 (2), 345-352
    DOI 10.1038/s41591-021-01621-1, PubMed 35027758
  207. Chakraborty S, Woldemariam NT, Visnovska T, Rise ML, Boyce D, Santander J, Andreassen R (2022)
    Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
    Biology (Basel), 11 (1)
    DOI 10.3390/biology11010130, PubMed 35053128
  208. Skotheim RI, Axcrona U, Axcrona K (2022)
    Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
    Eur Urol, 81 (4), 431
    DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159
  209. Hjerkind KV, Johansson ALV, Trewin CB, Russnes HG, Ursin G (2022)
    Incidence of breast cancer subtypes in immigrant and non-immigrant women in Norway
    Breast Cancer Res, 24 (1), 4
    DOI 10.1186/s13058-021-01498-5, PubMed 35012613
  210. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy, 18 (2), 467-469
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  211. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci, 1510 (1), 79-99
    DOI 10.1111/nyas.14745, PubMed 35000205
  212. Ji X, Lin L, Fan J, Li Y, Wei Y, Shen S, Su L, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Zhang R, Chen F, Christiani DC (2022)
    Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC
    Mol Oncol, 16 (3), 717-731
    DOI 10.1002/1878-0261.13167, PubMed 34932879
  213. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
    DOI 10.1093/nar/gkab1101, PubMed 34850127
  214. Ahearn TU, Zhang H, Michailidou K, Milne RL, Bolla MK, Dennis J, Dunning AM, Lush M, Wang Q, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Augustinsson A, Baten A, Becher H, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H et al. (2022)
    Common variants in breast cancer risk loci predispose to distinct tumor subtypes
    Breast Cancer Res, 24 (1), 2
    DOI 10.1186/s13058-021-01484-x, PubMed 34983606
  215. Sivanesan S, Taskén KA, Grytli HH (2022)
    Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
    JAMA Netw Open, 5 (1), e2145230
    DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
  216. Nguyen L, Nguyen E, Tran C, Nguyen K, Devarajan A, Berg K, Hirschberg H (2022)
    Sonochemical Internalization of Bleomycin Inhibits Adenocarcinoma Breast Tumor Development in an Orthotopic Rat Model
    J Environ Pathol Toxicol Oncol, 41 (2), 25-35
    DOI 10.1615/JEnvironPatholToxicolOncol.2021040536, PubMed 35695649
  217. Bajor M, Graczyk-Jarzynka A, Marhelava K, Burdzinska A, Muchowicz A, Goral A, Zhylko A, Soroczynska K, Retecki K, Krawczyk M, Klopotowska M, Pilch Z, Paczek L, Malmberg KJ, Wälchli S, Winiarska M, Zagozdzon R (2022)
    PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells
    J Immunother Cancer, 10 (1)
    DOI 10.1136/jitc-2021-002500, PubMed 35078921
  218. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  219. Athanasiadis P, Ianevski A, Skånland SS, Aittokallio T (2022)
    Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells
    Methods Mol Biol, 2449, 327-348
    DOI 10.1007/978-1-0716-2095-3_14, PubMed 35507270
  220. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    J Acquir Immune Defic Syndr, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817, PubMed 34878437
  221. Helland Å, Andersen KK, Myklebust TÅ, Johannesen TB, Aarøe J, Enerly E (2022)
    EGFR-mutation testing and TKI treatment patterns in locally advanced and metastatic NSCLC in Norway - A nationwide retrospective cohort study
    Cancer Treat Res Commun, 33, 100636
    DOI 10.1016/j.ctarc.2022.100636, PubMed 36155129
  222. Kryeziu K, Bergsland CH, Guren TK, Sveen A, Lothe RA (2022)
    Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
    Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
    DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193

Publications 2021

  1. Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A (2021)
    Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
    Sci Total Environ, 814, 152732
    DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025
  2. Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
    Cell Rep, 37 (13), 110186
    DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
  3. Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
    E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
    Mol Oncol, 16 (12), 2312-2329
    DOI 10.1002/1878-0261.13159, PubMed 34890102
  4. White JM, Schiffer JT, Bender Ignacio RA, Xu S, Kainov D, Ianevski A, Aittokallio T, Frieman M, Olinger GG, Polyak SJ (2021)
    Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
    mBio, 12 (6), e0334721
    DOI 10.1128/mbio.03347-21, PubMed 34933447
  5. Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy, 18 (8), 1915-1931
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  6. Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol Oncol, 16 (5), 1153-1170
    DOI 10.1002/1878-0261.13153, PubMed 34861096
  7. Reint G, Li Z, Labun K, Keskitalo S, Soppa I, Mamia K, Tolo E, Szymanska M, Meza-Zepeda LA, Lorenz S, Cieslar-Pobuda A, Hu X, Bordin DL, Staerk J, Valen E, Schmierer B, Varjosalo M, Taipale J, Haapaniemi E (2021)
    Rapid genome editing by CRISPR-Cas9-POLD3 fusion
    Elife, 10
    DOI 10.7554/eLife.75415, PubMed 34898428
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  201. Fleten KG, Eksteen JJ, Mauseth B, Camilio KA, Vasskog T, Sveinbjørnsson B, Rekdal Ø, Mælandsmo GM, Flatmark K (2021)
    Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
    Sci Rep, 11 (1), 6731
    DOI 10.1038/s41598-021-86239-6, PubMed 33762676
  202. Brück OE, Lallukka-Brück SE, Hohtari HR, Ianevski A, Ebeling FT, Kovanen PE, Kytölä SI, Aittokallio TA, Ramos PM, Porkka KV, Mustjoki SM (2021)
    Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS
    Blood Cancer Discov, 2 (3), 238-249
    DOI 10.1158/2643-3230.BCD-20-0162, PubMed 34661156
  203. Georgiesh T, Namløs HM, Sharma N, Lorenz S, Myklebost O, Bjerkehagen B, Meza-Zepeda LA, Boye K (2021)
    Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
    Pathology, 53 (6), 713-719
    DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702
  204. Oksvold MP, Berglund UW, Gad H, Bai B, Stokke T, Rein ID, Pham T, Sanjiv K, Øy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Våtsveen TK (2021)
    Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
    Sci Rep, 11 (1), 6317
    DOI 10.1038/s41598-021-85613-8, PubMed 33737576
  205. Stabell M, Sæther T, Røhr ÅK, Gabrielsen OS, Myklebost O (2021)
    Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
    Biochem Biophys Res Commun, 552, 91-97
    DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765
  206. Herring S, Oda JM, Wagoner J, Kirchmeier D, O'Connor A, Nelson EA, Huang Q, Liang Y, DeWald LE, Johansen LM, Glass PJ, Olinger GG, Ianevski A, Aittokallio T, Paine MF, Fink SL, White JM, Polyak SJ (2021)
    Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs
    Antimicrob Agents Chemother, 65 (4)
    DOI 10.1128/AAC.01146-20, PubMed 33468464
  207. Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
    Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Eur J Cancer, 148, 124-133
    DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
  208. Langenbucher A, Bowen D, Sakhtemani R, Bournique E, Wise JF, Zou L, Bhagwat AS, Buisson R, Lawrence MS (2021)
    An extended APOBEC3A mutation signature in cancer
    Nat Commun, 12 (1), 1602
    DOI 10.1038/s41467-021-21891-0, PubMed 33707442
  209. Kjøsen G, Rydenfelt K, Horneland R, Aandahl EM, Line PD, Dorenberg E, Berstad AE, Brabrand K, Hagen G, Pischke SE, Bergmann GB, Nordheim E, Jenssen TG, Tønnessen TI, Haugaa H (2021)
    Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
    PLoS One, 16 (3), e0247615
    DOI 10.1371/journal.pone.0247615, PubMed 33705460
  210. Grad I, Hanes R, Ayuda-Durán P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
    Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
    PLoS One, 16 (3), e0248140
    DOI 10.1371/journal.pone.0248140, PubMed 33690666
  211. Hølmebakk T, Boye K (2021)
    ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (11), 6846-6847
    DOI 10.1245/s10434-021-09608-5, PubMed 33687615
  212. Napoli E, Bønsdorff TB, Jorstad IS, Bruland ØS, Larsen RH, Westrøm S (2021)
    Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use
    PLoS One, 16 (3), e0248133
    DOI 10.1371/journal.pone.0248133, PubMed 33662039
  213. Lone AM, Taskén K (2021)
    Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
    Mol Pharmacol, 99 (5), 370-382
    DOI 10.1124/molpharm.120.000170, PubMed 33674363
  214. Hølmebakk T, Wiedswang AM, Meza-Zepeda LA, Hompland I, Lobmaier IVK, Berner JM, Stoldt S, Boye K (2021)
    Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
    Ann Surg Oncol, 28 (11), 6837-6845
    DOI 10.1245/s10434-021-09605-8, PubMed 33651216
  215. Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
    Sealing holes in cellular membranes
    EMBO J, 40 (7), e106922
    DOI 10.15252/embj.2020106922, PubMed 33644904
  216. Luna S, Torices L, Mingo J, Amo L, Rodríguez-Escudero I, Ruiz-Ibarlucea P, Erramuzpe A, Cortés JM, Tejada MI, Molina M, Nunes-Xavier CE, López JI, Cid VJ, Pulido R (2021)
    A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
    Hum Mutat, 42 (5), 551-566
    DOI 10.1002/humu.24186, PubMed 33600059
  217. Jaiswal A, Gautam P, Pietilä EA, Timonen S, Nordström N, Akimov Y, Sipari N, Tanoli Z, Fleischer T, Lehti K, Wennerberg K, Aittokallio T (2021)
    Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
    Mol Syst Biol, 17 (3), e9526
    DOI 10.15252/msb.20209526, PubMed 33750001
  218. Helwa R, Gansmo LB, Bjørnslett M, Halle MK, Werner HMJ, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
    Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
    Biomarkers, 26 (4), 302-308
    DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
  219. Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
    Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
    Sci Rep, 11 (1), 4613
    DOI 10.1038/s41598-021-84268-9, PubMed 33633289
  220. Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
    Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
    Autophagy, 17 (4), 1046-1048
    DOI 10.1080/15548627.2021.1887548, PubMed 33629888
  221. Akimov Y, Aittokallio T (2021)
    Re-defining synthetic lethality by phenotypic profiling for precision oncology
    Cell Chem Biol, 28 (3), 246-256
    DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125
  222. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
    A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
    Sci Transl Med, 13 (582)
    DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
  223. Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
    DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
    Atherosclerosis, 324, 123-132
    DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
  224. Siddiqui FA, Parkkola H, Vukic V, Oetken-Lindholm C, Jaiswal A, Kiriazis A, Pavic K, Aittokallio T, Salminen TA, Abankwa D (2021)
    Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling
    Cancers (Basel), 13 (4)
    DOI 10.3390/cancers13040927, PubMed 33672199
  225. Gaustad JV, Simonsen TG, Hansem LMK, Rofstad EK (2021)
    Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
    Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
    DOI 10.1007/s00259-021-05243-0, PubMed 33606081
  226. Juzeniene A, Stenberg VY, Bruland ØS, Larsen RH (2021)
    Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
    Cancers (Basel), 13 (4)
    DOI 10.3390/cancers13040779, PubMed 33668474
  227. Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
    Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
    Cancer Immunol Immunother, 70 (9), 2617-2624
    DOI 10.1007/s00262-021-02876-w, PubMed 33580363
  228. Tanoli Z, Vähä-Koskela M, Aittokallio T (2021)
    Artificial intelligence, machine learning, and drug repurposing in cancer
    Expert Opin Drug Discov, 16 (9), 977-989
    DOI 10.1080/17460441.2021.1883585, PubMed 33543671
  229. Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
    The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
    J Cell Sci, 134 (3)
    DOI 10.1242/jcs.250670, PubMed 33468622
  230. Ben-Elazar S, Aure MR, Jonsdottir K, Leivonen SK, Kristensen VN, Janssen EAM, Kleivi Sahlberg K, Lingjærde OC, Yakhini Z (2021)
    miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
    PLoS Comput Biol, 17 (2), e1008608
    DOI 10.1371/journal.pcbi.1008608, PubMed 33566819
  231. Krüger K, Silwal-Pandit L, Wik E, Straume O, Stefansson IM, Borgen E, Garred Ø, Naume B, Engebraaten O, Akslen LA (2021)
    Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
    Sci Rep, 11 (1), 3388
    DOI 10.1038/s41598-021-81914-0, PubMed 33564016
  232. Davydova E, Shimazu T, Schuhmacher MK, Jakobsson ME, Willemen HLDM, Liu T, Moen A, Ho AYY, Małecki J, Schroer L, Pinto R, Suzuki T, Grønsberg IA, Sohtome Y, Akakabe M, Weirich S, Kikuchi M, Olsen JV, Dohmae N, Umehara T, Sodeoka M, Siino V, McDonough MA, Eijkelkamp N, Schofield CJ et al. (2021)
    The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
    Nat Commun, 12 (1), 891
    DOI 10.1038/s41467-020-20670-7, PubMed 33563959
  233. Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
    Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
    FEBS Open Bio, 11 (3), 724-740
    DOI 10.1002/2211-5463.13098, PubMed 33512765
  234. Gorgen A, Guttormsen M, Larsen AC, Siem S, Adli E, Edin NFJ, Gjersdal H, Henriksen G, Malinen E, Modamio V, Schoultz B, Sobas PA, Theodossiou TA, Wikne JC (2021)
    The Oslo Cyclotron Laboratory
    Eur. Phys. J. Plus, 136 (2), 181
    DOI 10.1140/epjp/s13360-021-01150-3
  235. Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
    Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
    Int J Environ Res Public Health, 18 (4)
    DOI 10.3390/ijerph18041470, PubMed 33557277
  236. Berishvili E, Kaiser L, Cohen M, Berney T, Scholz H, Floisand Y, Mattsson J (2021)
    Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
    Stem Cell Rev Rep, 17 (1), 63-70
    DOI 10.1007/s12015-020-10004-x, PubMed 32696426
  237. Skotland T, Sandvig K (2021)
    Transport of nanoparticles across the endothelial cell layer
    Nano Today, 36, 101029
    DOI 10.1016/j.nantod.2020.101029
  238. Johansson ALV, Trewin CB, Fredriksson I, Reinertsen KV, Russnes H, Ursin G (2021)
    In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study
    Breast Cancer Res, 23 (1), 17
    DOI 10.1186/s13058-021-01393-z, PubMed 33526044
  239. Ianevski A, Lahtela J, Javarappa KK, Sergeev P, Ghimire BR, Gautam P, Vähä-Koskela M, Turunen L, Linnavirta N, Kuusanmäki H, Kontro M, Porkka K, Heckman CA, Mattila P, Wennerberg K, Giri AK, Aittokallio T (2021)
    Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
    Sci Adv, 7 (8)
    DOI 10.1126/sciadv.abe4038, PubMed 33608276
  240. Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
    Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
    Toxins (Basel), 13 (2)
    DOI 10.3390/toxins13020102, PubMed 33573355
  241. Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
    FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
    Commun Biol, 4 (1), 127
    DOI 10.1038/s42003-021-01647-8, PubMed 33514811
  242. Sakurai M, Mori T, Kato K, Kanaya M, Mizuno S, Shiratori S, Wakayama T, Uchida N, Kobayashi H, Kubo K, Amano I, Ohta T, Miyazaki Y, Kanda J, Fukuda T, Atsuta Y, Kondo E, Adult Lymphoma Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT) (2021)
    Outcome of allogeneic hematopoietic stem cell transplantation for follicular lymphoma relapsing after autologous transplantation: analysis of the Japan Society for Hematopoietic Cell Transplantation
    Bone Marrow Transplant, 56 (6), 1462-1466
    DOI 10.1038/s41409-020-01192-8, PubMed 33514920
  243. Hompland T, Fjeldbo CS, Lyng H (2021)
    Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
    Cancers (Basel), 13 (3)
    DOI 10.3390/cancers13030499, PubMed 33525508
  244. Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
    Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
    JCO Precis Oncol, 5
    DOI 10.1200/PO.20.00086, PubMed 34036235
  245. Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
    MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
    Mol Genet Metab Rep, 26, 100710
    DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904
  246. Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
    Editorial: Genomic Colocalization and Enrichment Analyses
    Front Genet, 11, 617876
    DOI 10.3389/fgene.2020.617876, PubMed 33574832
  247. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
  248. Breast Cancer Association Consortium, Dorling L, Carvalho S, Allen J, González-Neira A, Luccarini C, Wahlström C, Pooley KA, Parsons MT, Fortuno C, Wang Q, Bolla MK, Dennis J, Keeman R, Alonso MR, Álvarez N, Herraez B, Fernandez V, Núñez-Torres R, Osorio A, Valcich J, Li M, Törngren T, Harrington PA, Baynes C et al. (2021)
    Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
    N Engl J Med, 384 (5), 428-439
    DOI 10.1056/NEJMoa1913948, PubMed 33471991
  249. Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
    Wetting regulates autophagy of phase-separated compartments and the cytosol
    Nature, 591 (7848), 142-146
    DOI 10.1038/s41586-020-2992-3, PubMed 33473217
  250. Skånland SS, Mato AR (2021)
    Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
    Blood Adv, 5 (1), 334-343
    DOI 10.1182/bloodadvances.2020003423, PubMed 33570649
  251. Galili B, Tekpli X, Kristensen VN, Yakhini Z (2021)
    Efficient gene expression signature for a breast cancer immuno-subtype
    PLoS One, 16 (1), e0245215
    DOI 10.1371/journal.pone.0245215, PubMed 33434192
  252. Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
    Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 187 (2), 515-523
    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
  253. Otterhaug T, Janetzki S, Welters MJP, Håkerud M, Nedberg AG, Edwards VT, Boekestijn S, Loof NM, Selbo PK, Olivecrona H, van der Burg SH, Høgset A (2021)
    Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
    Front Immunol, 11, 576756
    DOI 10.3389/fimmu.2020.576756, PubMed 33488576
  254. Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
    Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
    Mol Oncol, 15 (4), 830-845
    DOI 10.1002/1878-0261.12885, PubMed 33325154
  255. Terkelsen T, Pernemalm M, Gromov P, Børresen-Dale AL, Krogh A, Haakensen VD, Lethiö J, Papaleo E, Gromova I (2021)
    High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
    Mol Oncol, 15 (2), 429-461
    DOI 10.1002/1878-0261.12850, PubMed 33176066
  256. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  257. Sharma A, Colonna G (2021)
    System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
    Mol Diagn Ther, 25 (1), 9-27
    DOI 10.1007/s40291-020-00505-3, PubMed 33475988
  258. Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, Leusen J, Andersen JT (2021)
    Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
    MAbs, 13 (1), 1893888
    DOI 10.1080/19420862.2021.1893888, PubMed 33691596
  259. Sioud M (2021)
    RNA Interference: Story and Mechanisms
    Methods Mol Biol, 2282, 1-15
    DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566
  260. Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
    From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
    Prog Chem Org Nat Prod, 115, 59-114
    DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641
  261. Li RG, Napoli E, Jorstad IS, Bønsdorff TB, Juzeniene A, Bruland ØS, Larsen RH, Westrøm S (2021)
    Calcium Carbonate Microparticles as Carriers of 224Ra: Impact of Specific Activity in Mice with Intraperitoneal Ovarian Cancer
    Curr Radiopharm, 14 (2), 145-153
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Publications 2020

  1. Bergeron DE, Collins SM, Pibida L, Cessna JT, Fitzgerald R, Zimmerman BE, Ivanov P, Keightley JD, Napoli E (2020)
    Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison
    Appl Radiat Isot, 170, 109572
    DOI 10.1016/j.apradiso.2020.109572, PubMed 33461017
  2. Pulkkinen OI, Gautam P, Mustonen V, Aittokallio T (2020)
    Multiobjective optimization identifies cancer-selective combination therapies
    PLoS Comput Biol, 16 (12), e1008538
    DOI 10.1371/journal.pcbi.1008538, PubMed 33370253
  3. Öjlert ÅK, Nebdal D, Lund-Iversen M, Åstrøm Ellefsen R, Brustugun OT, Gran JM, Halvorsen AR, Helland Å (2020)
    Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer - predictors of response and impact of previous radiotherapy
    Acta Oncol, 60 (2), 149-156
    DOI 10.1080/0284186X.2020.1854851, PubMed 33356733
  4. Graim K, Gorenshteyn D, Robinson DG, Carriero NJ, Cahill JA, Chakrabarti R, Goldschmidt MH, Durham AC, Funk J, Storey JD, Kristensen VN, Theesfeld CL, Sorenmo KU, Troyanskaya OG (2020)
    Modeling molecular development of breast cancer in canine mammary tumors
    Genome Res, 31 (2), 337-347
    DOI 10.1101/gr.256388.119, PubMed 33361113
  5. Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Karlstad Ø, Juzeniene A, Ghiasvand R, Larsen IK, Green AC, Veierød MB, Robsahm TE (2020)
    Use of Immunomodulating Drugs and Risk of Cutaneous Melanoma: A Nationwide Nested Case-Control Study
    Clin Epidemiol, 12, 1389-1401
    DOI 10.2147/CLEP.S269446, PubMed 33376408
  6. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
    A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
    J Biol Chem, 296, 100179
    DOI 10.1074/jbc.RA120.015285, PubMed 33303632
  7. Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Körner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang X, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang W, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR et al. (2020)
    Anti-tumour immunity induces aberrant peptide presentation in melanoma
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