Publications
Publications published since 2018 from OUS - Institute for Cancer Research
1264 publications found (only first 1000 shown)
Publications 2023
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Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
Blood Adv, 7 (23), 7216-7230
DOI 10.1182/bloodadvances.2023010158, PubMed 37695745 -
Efficacy of immune checkpoint inhibitors in alveolar soft-part sarcoma: results from a retrospective worldwide registry
ESMO Open, 8 (6), 102045 (in press)
DOI 10.1016/j.esmoop.2023.102045, PubMed 38016251 -
Initial investigation of using Norwegian health data for the purpose of external comparator arms - an example for non-small cell lung cancer
Acta Oncol, 62 (12), 1642-1648
DOI 10.1080/0284186X.2023.2264484, PubMed 37801361 -
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc (in press)
DOI 10.1038/s41596-023-00903-x, PubMed 37996540 -
Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
Int Immunopharmacol, 126, 111225 (in press)
DOI 10.1016/j.intimp.2023.111225, PubMed 37988911 -
Macrophages as a photosensitizer delivery system for photodynamic therapy: Potential for the local treatment of resected glioblastoma
Photodiagnosis Photodyn Ther, 103897 (in press)
DOI 10.1016/j.pdpdt.2023.103897, PubMed 37984525 -
Long-Smoldering T-prolymphocytic Leukemia: A Case Report and a Review of the Literature
Curr Oncol, 30 (11), 10007-10018
DOI 10.3390/curroncol30110727, PubMed 37999147 -
CELLULAR, A Cell Autophagy Imaging Dataset
Sci Data, 10 (1), 806
DOI 10.1038/s41597-023-02687-x, PubMed 37973836 -
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkad1059, PubMed 37962376 -
Impact of rare structural variant events in newly diagnosed multiple myeloma
Clin Cancer Res (in press)
DOI 10.1158/1078-0432.CCR-23-1045, PubMed 37939148 -
Small molecule inhibitors targeting regulatory T cells for cancer treatment
Eur J Immunol, e2350448 (in press)
DOI 10.1002/eji.202350448, PubMed 37937687 -
The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
J Immunol, 211 (9), 1348-1358
DOI 10.4049/jimmunol.2300406, PubMed 37737664 -
MetaGate: Interactive Analysis of High-Dimensional Cytometry Data with Meta Data Integration
bioRxiv
DOI 10.1101/2023.10.27.564454, PubMed 37961421 -
ASO Visual Abstract: Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
Ann Surg Oncol, 30 (12), 7637-7638
DOI 10.1245/s10434-023-14105-y, PubMed 37589802 -
Characterization and clinical impact of the tumor microenvironment in post-transplant aggressive B-cell lymphomas
Haematologica, 108 (11), 3044-3057
DOI 10.3324/haematol.2023.282831, PubMed 37259566 -
Removal of hypersignaling endosomes by simaphagy
Autophagy, 1-23 (in press)
DOI 10.1080/15548627.2023.2267958, PubMed 37840274 -
Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015218, PubMed 37894899 -
Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
EBioMedicine, 97, 104829
DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931 -
Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
Hered Cancer Clin Pract, 21 (1), 19
DOI 10.1186/s13053-023-00263-3, PubMed 37821984 -
Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells
bioRxiv
DOI 10.1101/2023.10.09.557143, PubMed 37873468 -
Short-term results after robot-assisted surgery for primary rectal cancers requiring beyond total mesorectal excision in multiple compartments
Scand J Surg, 14574969231200654 (in press)
DOI 10.1177/14574969231200654, PubMed 37787437 -
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
Cell Mol Life Sci, 80 (10), 311
DOI 10.1007/s00018-023-04964-9, PubMed 37783936 -
Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma
Clin Cancer Res, 29 (19), 3901-3913
DOI 10.1158/1078-0432.CCR-22-3209, PubMed 37449980 -
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807 -
Stability of metabolic tumor volume may enable radiotherapy dose painting in anal cancer
Phys Med, 114, 103151
DOI 10.1016/j.ejmp.2023.103151, PubMed 37813051 -
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Nat Commun, 14 (1), 6035
DOI 10.1038/s41467-023-41634-7, PubMed 37758698 -
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation
EBioMedicine, 96, 104811
DOI 10.1016/j.ebiom.2023.104811, PubMed 37741009 -
MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
Cancers (Basel), 15 (18)
DOI 10.3390/cancers15184662, PubMed 37760629 -
The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition
Front Immunol, 14, 1226445
DOI 10.3389/fimmu.2023.1226445, PubMed 37799721 -
ATPase-regulated autophagosome biogenesis
Autophagy, 1-2 (in press)
DOI 10.1080/15548627.2023.2255967, PubMed 37722386 -
Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood
Clin Epigenetics, 15 (1), 151
DOI 10.1186/s13148-023-01563-0, PubMed 37710283 -
The separate axes of TECPR1 and ATG16L1 in CASM
Autophagy, 1-2 (in press)
DOI 10.1080/15548627.2023.2255462, PubMed 37676042 -
Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells
N Biotechnol, 77, 139-148
DOI 10.1016/j.nbt.2023.09.002, PubMed 37673373 -
Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
Mol Oncol, 17 (11), 2432-2450
DOI 10.1002/1878-0261.13514, PubMed 37622176 -
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406 -
Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey
JCO Precis Oncol, 7, e2300440
DOI 10.1200/PO.23.00440, PubMed 37897815 -
Phosphoinositides in New Spaces
Cold Spring Harb Perspect Biol, 15 (9)
DOI 10.1101/cshperspect.a041406, PubMed 37463718 -
Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels
Radiother Oncol, 188, 109875
DOI 10.1016/j.radonc.2023.109875, PubMed 37640161 -
The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
iScience, 26 (10), 107726
DOI 10.1016/j.isci.2023.107726, PubMed 37720104 -
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
NPJ Vaccines, 8 (1), 126
DOI 10.1038/s41541-023-00713-y, PubMed 37607971 -
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires
Blood Adv, 7 (16), 4492-4504
DOI 10.1182/bloodadvances.2023009827, PubMed 37327114 -
Imaging of 212Pb in mice with a clinical SPECT/CT
EJNMMI Phys, 10 (1), 47
DOI 10.1186/s40658-023-00571-6, PubMed 37603123 -
Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
Biophys J (in press)
DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785 -
A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
Cancers (Basel), 15 (16)
DOI 10.3390/cancers15164124, PubMed 37627152 -
Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
Clin Cancer Res, 29 (16), 3026-3036
DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632 -
ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
Ann Surg Oncol, 30 (12), 7633-7634
DOI 10.1245/s10434-023-14058-2, PubMed 37573284 -
Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
BMC Res Notes, 16 (1), 167
DOI 10.1186/s13104-023-06437-5, PubMed 37568187 -
Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
Int J Cancer, 153 (10), 1819-1828
DOI 10.1002/ijc.34666, PubMed 37551617 -
Modified study designs to expand treatment options in personalised oncology: a multistakeholder view
Eur J Cancer, 194, 113278
DOI 10.1016/j.ejca.2023.113278, PubMed 37820553 -
The expanding organelle lipidomes: current knowledge and challenges
Cell Mol Life Sci, 80 (8), 237
DOI 10.1007/s00018-023-04889-3, PubMed 37530856 -
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?
Cold Spring Harb Perspect Biol, 15 (8)
DOI 10.1101/cshperspect.a041415, PubMed 37277192 -
Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants
PLoS One, 18 (8), e0289369
DOI 10.1371/journal.pone.0289369, PubMed 37527256 -
A phosphoinositide kinase triggers migrasome formation
Cell Res, 33 (8), 577-578
DOI 10.1038/s41422-023-00822-2, PubMed 37165066 -
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
Cell Mol Life Sci, 80 (8), 235
DOI 10.1007/s00018-023-04864-y, PubMed 37523003 -
'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
Histopathology, 83 (6), 853-869
DOI 10.1111/his.15012, PubMed 37501635 -
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
Mol Oncol, 17 (9), 1803-1820
DOI 10.1002/1878-0261.13488, PubMed 37458534 -
Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
Ann Surg Oncol, 30 (12), 7602-7611
DOI 10.1245/s10434-023-13964-9, PubMed 37481493 -
Obesity-associated changes in molecular biology of primary breast cancer
Nat Commun, 14 (1), 4418
DOI 10.1038/s41467-023-39996-z, PubMed 37479706 -
Protrudin-mediated ER-endosome contact sites promote phagocytosis
Cell Mol Life Sci, 80 (8), 216
DOI 10.1007/s00018-023-04862-0, PubMed 37468729 -
hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
PLoS One, 18 (7), e0286330
DOI 10.1371/journal.pone.0286330, PubMed 37467208 -
Analysis of ATG4C function in vivo
Autophagy, 19 (11), 2912-2933
DOI 10.1080/15548627.2023.2234799, PubMed 37459465 -
Endocytic trafficking of connexins in cancer pathogenesis
Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772 -
Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities
Br J Cancer, 129 (8), 1212-1224
DOI 10.1038/s41416-023-02361-4, PubMed 37454231 -
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
J Mammary Gland Biol Neoplasia, 28 (1), 17
DOI 10.1007/s10911-023-09544-y, PubMed 37450065 -
ATPase activity of DFCP1 controls selective autophagy
Nat Commun, 14 (1), 4051
DOI 10.1038/s41467-023-39641-9, PubMed 37422481 -
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525 -
Factors associated with failure to start consolidation durvalumab after definitive chemoradiation for locally advanced NSCLC
Front Oncol, 13, 1217424
DOI 10.3389/fonc.2023.1217424, PubMed 37476372 -
Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data
Nucleic Acids Res, 51 (W1), W57-W61
DOI 10.1093/nar/gkad390, PubMed 37178002 -
Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
bioRxiv
DOI 10.1101/2023.07.04.546825, PubMed 37461685 -
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Mol Oncol, 17 (10), 2041-2055
DOI 10.1002/1878-0261.13476, PubMed 37341140 -
Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection
Eur J Immunol, 53 (8), e2250254
DOI 10.1002/eji.202250254, PubMed 37102399 -
Acquired Cross-resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC paralogs
bioRxiv
DOI 10.1101/2023.06.23.546278, PubMed 37425738 -
Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells
iScience, 26 (7), 107209
DOI 10.1016/j.isci.2023.107209, PubMed 37485377 -
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
Cancers (Basel), 15 (13)
DOI 10.3390/cancers15133313, PubMed 37444426 -
A Qualitative Study of Barriers and Facilitators to Integrating Medications for Opioid Use Disorder and HIV Preexposure Prophylaxis for Adolescents and Young Adults
J Addict Med, 17 (6), e349-e354
DOI 10.1097/ADM.0000000000001195, PubMed 37934522 -
Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
Fam Cancer, 22 (4), 437-448
DOI 10.1007/s10689-023-00341-4, PubMed 37341816 -
Optical Properties and Interference Effects of the Lens Mitochondrion
Membranes (Basel), 13 (6)
DOI 10.3390/membranes13060610, PubMed 37367815 -
Determination of CAR T cell metabolism in an optimized protocol
Front Bioeng Biotechnol, 11, 1207576
DOI 10.3389/fbioe.2023.1207576, PubMed 37409169 -
A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
Nat Commun, 14 (1), 3561
DOI 10.1038/s41467-023-39085-1, PubMed 37322009 -
Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
ArXiv
PubMed 37396610 -
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
EMBO Rep, 24 (8), e56100
DOI 10.15252/embr.202256100, PubMed 37291955 -
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Nat Commun, 14 (1), 3375
DOI 10.1038/s41467-023-39097-x, PubMed 37291203 -
siRNA screening reveals that SNAP29 contributes to exosome release
Cell Mol Life Sci, 80 (7), 177
DOI 10.1007/s00018-023-04822-8, PubMed 37285022 -
Author Correction: The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
Sci Rep, 13 (1), 9186
DOI 10.1038/s41598-023-36328-5, PubMed 37280349 -
Immunogenic cell death after combined treatment with radiation and ATR inhibitors is dually regulated by apoptotic caspases
Front Immunol, 14, 1138920
DOI 10.3389/fimmu.2023.1138920, PubMed 37346039 -
Use of antihypertensive drugs and risk of cutaneous melanoma: a nationwide nested case-control study
Int J Epidemiol, 52 (3), 887-898
DOI 10.1093/ije/dyac223, PubMed 36413027 -
Generalizability and Diagnostic Performance of AI Models for Thyroid US
Radiology, 307 (5), e221157
DOI 10.1148/radiol.221157, PubMed 37338356 -
Efficient chimeric antigen receptor targeting of a central epitope of CD22
J Biol Chem, 299 (7), 104883
DOI 10.1016/j.jbc.2023.104883, PubMed 37269947 -
"Evaluation of ROS1 expression and rearrangements in a large cohort of early-stage lung cancer"
Diagn Pathol, 18 (1), 70
DOI 10.1186/s13000-023-01357-1, PubMed 37237384 -
Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey
Front Oncol, 13, 1141810
DOI 10.3389/fonc.2023.1141810, PubMed 37293588 -
How the initial discovery of modified RNA enabled evasion of innate immune responses and facilitated the development of RNA therapeutics
Scand J Immunol, 98 (1), e13282
DOI 10.1111/sji.13282, PubMed 37132451 -
Bile acid metabolites in early pregnancy and risk of gestational diabetes mellitus: Results from a prospective cohort study
Diabetes Obes Metab, 25 (8), 2255-2267
DOI 10.1111/dom.15104, PubMed 37161712 -
The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
Sci Rep, 13 (1), 7339
DOI 10.1038/s41598-023-34087-x, PubMed 37147361 -
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Circ Res, 132 (11), e188-e205
DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790 -
The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL
Cancers (Basel), 15 (9)
DOI 10.3390/cancers15092527, PubMed 37173993 -
Long-term follow-up of colorectal cancer screening attendees identifies differences in Phascolarctobacterium spp. using 16S rRNA and metagenome sequencing
Front Oncol, 13, 1183039
DOI 10.3389/fonc.2023.1183039, PubMed 37182146 -
Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
Ann Oncol, 34 (7), 578-588
DOI 10.1016/j.annonc.2023.04.005, PubMed 37100205 -
Analysis of RNA Polymerase II Chromatin Binding by Flow Cytometry
Bio Protoc, 13 (8), e4659
DOI 10.21769/BioProtoc.4659, PubMed 37113330 -
Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting
Int J Mol Sci, 24 (8)
DOI 10.3390/ijms24087493, PubMed 37108657 -
A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
PLoS Comput Biol, 19 (4), e1010995
DOI 10.1371/journal.pcbi.1010995, PubMed 37068117 -
A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
Cell Death Discov, 9 (1), 125
DOI 10.1038/s41420-023-01426-w, PubMed 37055391 -
Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 1767
DOI 10.1038/s41467-023-37488-8, PubMed 36997540 -
NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts
Blood, 141 (13), 1584-1596
DOI 10.1182/blood.2022016934, PubMed 36375120 -
Precision Killing of M2 Macrophages with Phage-Displayed Peptide-Photosensitizer Conjugates
Cancers (Basel), 15 (7)
DOI 10.3390/cancers15072009, PubMed 37046671 -
Effect of mTOR Inhibition with Sirolimus on Natural Killer Cell Reconstitution in Allogeneic Stem Cell Transplantation
Transplant Cell Ther, 29 (6), 376.e1-376.e11
DOI 10.1016/j.jtct.2023.03.023, PubMed 36966873 -
Antibody Surface Profiling Identifies Glycoforms in Multiple Myeloma as Targets for Immunotherapy: From Antibody Derivatives to Mimetic Peptides for Killing Tumor Cells
Cancers (Basel), 15 (7)
DOI 10.3390/cancers15071934, PubMed 37046595 -
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
iScience, 26 (4), 106448
DOI 10.1016/j.isci.2023.106448, PubMed 37020951 -
Determining a minimum data set for reporting clinical and radiologic data for pseudomyxoma peritonei
Pleura Peritoneum, 8 (1), 1-9
DOI 10.1515/pp-2022-0200, PubMed 37020469 -
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
EClinicalMedicine, 58, 101909
DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409 -
Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
bioRxiv
DOI 10.1101/2023.02.01.526672, PubMed 36993681 -
External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification
Eur J Surg Oncol, 49 (8), 1481-1488
DOI 10.1016/j.ejso.2023.03.206, PubMed 36935222 -
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Proc Natl Acad Sci U S A, 120 (12), e2220320120
DOI 10.1073/pnas.2220320120, PubMed 36917669 -
OSCAR: Optimal subset cardinality regression using the L0-pseudonorm with applications to prognostic modelling of prostate cancer
PLoS Comput Biol, 19 (3), e1010333
DOI 10.1371/journal.pcbi.1010333, PubMed 36897911 -
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861 -
Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
Cell Commun Signal, 21 (1), 50
DOI 10.1186/s12964-023-01062-y, PubMed 36882786 -
Editorial: Targeted alpha particle therapy in oncology
Front Med (Lausanne), 10, 1165747
DOI 10.3389/fmed.2023.1165747, PubMed 36960341 -
High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE
Nat Biotechnol, 41 (11), 1543-1548
DOI 10.1038/s41587-023-01697-9, PubMed 36879008 -
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
Cell Rep Methods, 3 (3), 100417
DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380 -
Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
Circulation, 147 (16), 1221-1236
DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489 -
New frontiers in immune checkpoint B7-H3 (CD276) research and drug development
Mol Cancer, 22 (1), 43
DOI 10.1186/s12943-023-01751-9, PubMed 36859240 -
The quick reference card "Storage of urinary EVs" - A practical guideline tool for research and clinical laboratories
J Extracell Vesicles, 12 (3), e12286
DOI 10.1002/jev2.12286, PubMed 36916183 -
Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients
medRxiv
DOI 10.1101/2023.02.24.23286403, PubMed 36865297 -
Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
Front Oncol, 13, 1040665
DOI 10.3389/fonc.2023.1040665, PubMed 36910663 -
Autophagosome Biogenesis
Cells, 12 (4)
DOI 10.3390/cells12040668, PubMed 36831335 -
Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia
BioDrugs, 37 (2), 219-233
DOI 10.1007/s40259-023-00583-9, PubMed 36795353 -
A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
Cancer Res Commun, 3 (2), 235-244
DOI 10.1158/2767-9764.CRC-22-0295, PubMed 36968142 -
CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
J Cell Biol, 222 (4)
DOI 10.1083/jcb.202208062, PubMed 36752787 -
Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
Res Sq
DOI 10.21203/rs.3.rs-2488586/v1, PubMed 36798177 -
Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Biomedicines, 11 (2)
DOI 10.3390/biomedicines11020459, PubMed 36830995 -
Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
Front Mol Biosci, 10, 980433
DOI 10.3389/fmolb.2023.980433, PubMed 36818049 -
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
Proc Natl Acad Sci U S A, 120 (6), e2211368120
DOI 10.1073/pnas.2211368120, PubMed 36730202 -
Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer
JCO Clin Cancer Inform, 7, e2200159
DOI 10.1200/CCI.22.00159, PubMed 36821799 -
CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins
J Cell Sci, 136 (3)
DOI 10.1242/jcs.260327, PubMed 36606424 -
Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
Pharmaceutics, 15 (2)
DOI 10.3390/pharmaceutics15020437, PubMed 36839759 -
Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
Int J Mol Sci, 24 (3)
DOI 10.3390/ijms24032527, PubMed 36768851 -
High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
PLoS One, 18 (1), e0280507
DOI 10.1371/journal.pone.0280507, PubMed 36706086 -
Molecular characteristics of low-grade serous carcinoma in effusions
Cytopathology, 34 (2), 99-105
DOI 10.1111/cyt.13207, PubMed 36609991 -
Transcriptomic pan-cancer analysis using rank-based Bayesian inference
Mol Oncol, 17 (4), 548-563
DOI 10.1002/1878-0261.13354, PubMed 36562628 -
ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines
Genes (Basel), 14 (2)
DOI 10.3390/genes14020296, PubMed 36833223 -
New centres to carry out more clinical trials in Norway
Tidsskr Nor Laegeforen, 143 (2)
DOI 10.4045/tidsskr.22.0722, PubMed 36718905 -
Heritable defects in telomere and mitotic function selectively predispose to sarcomas
Science, 379 (6629), 253-260
DOI 10.1126/science.abj4784, PubMed 36656928 -
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Proc Natl Acad Sci U S A, 120 (4), e2210593120
DOI 10.1073/pnas.2210593120, PubMed 36656860 -
Dual targeting with 224Ra/212Pb-conjugates for targeted alpha therapy of disseminated cancers: A conceptual approach
Front Med (Lausanne), 9, 1051825
DOI 10.3389/fmed.2022.1051825, PubMed 36733936 -
Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia
Front Oncol, 12, 1075559
DOI 10.3389/fonc.2022.1075559, PubMed 36733367 -
Therapeutic cancer vaccination against telomerase: clinical developments in melanoma
Curr Opin Oncol, 35 (2), 100-106
DOI 10.1097/CCO.0000000000000922, PubMed 36700456 -
Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
Nanomedicine, 48, 102656
DOI 10.1016/j.nano.2023.102656, PubMed 36646195 -
Small anticancer drug release by light: Photochemical internalization of porphyrin-β-cyclodextrin nanoparticles
Carbohydr Polym, 306, 120579
DOI 10.1016/j.carbpol.2023.120579, PubMed 36746578 -
Extreme body mass index and survival in newly diagnosed multiple myeloma patients
Blood Cancer J, 13 (1), 13
DOI 10.1038/s41408-022-00782-7, PubMed 36631444 -
Fludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation
Ann Hematol, 102 (3), 651-661
DOI 10.1007/s00277-023-05084-x, PubMed 36631705 -
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713 -
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 115
DOI 10.1038/s41467-022-35624-4, PubMed 36611026 -
The genetic history of Scandinavia from the Roman Iron Age to the present
Cell, 186 (1), 32-46.e19
DOI 10.1016/j.cell.2022.11.024, PubMed 36608656 -
Editorial: Cell and Developmental Signalling in Neuroblastoma
Front Cell Dev Biol, 10, 1126352
DOI 10.3389/fcell.2022.1126352, PubMed 36684434 -
Impact of rare structural variant events in newly diagnosed multiple myeloma
bioRxiv
DOI 10.1101/2023.01.03.522573, PubMed 36711679 -
Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring
Anticancer Res, 43 (1), 351-357
DOI 10.21873/anticanres.16170, PubMed 36585179 -
screenwerk: a modular tool for the design and analysis of drug combination screens
Bioinformatics, 39 (1)
DOI 10.1093/bioinformatics/btac840, PubMed 36573326 -
PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
Haematologica, 108 (1), 9-21
DOI 10.3324/haematol.2022.281266, PubMed 35899388 -
Analysis of Spatial Molecular Data
Methods Mol Biol, 2614, 349-356
DOI 10.1007/978-1-0716-2914-7_20, PubMed 36587134 -
Evaluating comprehensive cancer networks; a review of standards and evaluation methods for care networks to inform a comparison with the OECI comprehensive cancer network standards
Acta Oncol, 62 (1), 15-24
DOI 10.1080/0284186X.2023.2170275, PubMed 36786345 -
Applying recommended definition of aggressive prostate cancer: a validation study using high-quality data from the Cancer Registry of Norway
Acta Oncol, 62 (1), 8-14
DOI 10.1080/0284186X.2023.2175331, PubMed 36762472 -
PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data
Bioinformatics, 39 (1)
DOI 10.1093/bioinformatics/btac766, PubMed 36448696
Publications 2022
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T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
Gigascience, 12
DOI 10.1093/gigascience/giad032, PubMed 37161965 -
The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
Cancer, 129 (6), 901-907
DOI 10.1002/cncr.34615, PubMed 36571512 -
Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
Front Cell Dev Biol, 10, 1022191
DOI 10.3389/fcell.2022.1022191, PubMed 36619857 -
Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
Eur J Hum Genet, 31 (5), 568-577
DOI 10.1038/s41431-022-01265-w, PubMed 36543932 -
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470 -
Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
Front Oncol, 12, 1104671
DOI 10.3389/fonc.2022.1104671, PubMed 36601476 -
Targeted Therapy on the Screen: Do We Hit the Target?
Clin Cancer Res, 28 (24), 5233-5234
DOI 10.1158/1078-0432.CCR-22-2707, PubMed 36240006 -
Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein
Front Immunol, 13, 1061696
DOI 10.3389/fimmu.2022.1061696, PubMed 36591303 -
Incorporating cross-voxel exchange for the analysis of dynamic contrast-enhanced imaging data: pre-clinical results
Phys Med Biol, 67 (24)
DOI 10.1088/1361-6560/aca512, PubMed 36541560 -
Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
Autophagy, 19 (7), 2159-2161
DOI 10.1080/15548627.2022.2155020, PubMed 36469687 -
[Checkpoint inhibitor-induced myocarditis]
Tidsskr Nor Laegeforen, 142 (18)
DOI 10.4045/tidsskr.21.0817, PubMed 36511752 -
Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only
N Engl J Med, 387 (23), 2126-2137
DOI 10.1056/NEJMoa2209454, PubMed 36477032 -
Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma
Br J Cancer, 128 (4), 678-690
DOI 10.1038/s41416-022-02067-z, PubMed 36476658 -
Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts
Cancer Treat Rev, 112, 102491
DOI 10.1016/j.ctrv.2022.102491, PubMed 36502615 -
A trans-omics assessment of gene-gene interaction in early-stage NSCLC
Mol Oncol, 17 (1), 173-187
DOI 10.1002/1878-0261.13345, PubMed 36408734 -
Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy
Front Oncol, 12, 1016958
DOI 10.3389/fonc.2022.1016958, PubMed 36531044 -
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
Cancer Discov, 12 (12), 2930-2953
DOI 10.1158/2159-8290.CD-21-0865, PubMed 36108220 -
Diversity of mitophagy pathways at a glance
J Cell Sci, 135 (23)
DOI 10.1242/jcs.259748, PubMed 36504076 -
Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
Eur Urol, 83 (2), 183
DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529 -
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Nat Med, 28 (12), 2573-2583
DOI 10.1038/s41591-022-02126-1, PubMed 36482103 -
Improvements in survival for patients with stage IV adenocarcinoma in the lung, diagnosed between 2010 - 2020 - A population-based registry study from Norway
Front Oncol, 12, 1017902
DOI 10.3389/fonc.2022.1017902, PubMed 36523970 -
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
Front Oncol, 12, 1040730
DOI 10.3389/fonc.2022.1040730, PubMed 36523963 -
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Nat Commun, 13 (1), 7341
DOI 10.1038/s41467-022-35127-2, PubMed 36446823 -
Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
Nucleic Acids Res, 50 (21), 12131-12148
DOI 10.1093/nar/gkac1143, PubMed 36477895 -
Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
Mar Drugs, 20 (12)
DOI 10.3390/md20120744, PubMed 36547891 -
Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
Pathol Res Pract, 241, 154243
DOI 10.1016/j.prp.2022.154243, PubMed 36481650 -
Targeted alpha therapy with the 224Ra/212Pb-TCMC-TP-3 dual alpha solution in a multicellular tumor spheroid model of osteosarcoma
Front Med (Lausanne), 9, 1058863
DOI 10.3389/fmed.2022.1058863, PubMed 36507500 -
Atezolizumab and stereotactic body radiotherapy in patients with advanced non-small cell lung cancer: safety, clinical activity and ctDNA responses-the ComIT-1 trial
Mol Oncol, 17 (3), 487-498
DOI 10.1002/1878-0261.13330, PubMed 36330681 -
The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
Hered Cancer Clin Pract, 20 (1), 37
DOI 10.1186/s13053-022-00243-z, PubMed 36411472 -
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828 -
[Whole brain radiotherapy should be restricted]
Tidsskr Nor Laegeforen, 142 (17)
DOI 10.4045/tidsskr.22.0696, PubMed 36416654 -
Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network
Brief Bioinform, 23 (6)
DOI 10.1093/bib/bbac456, PubMed 36305426 -
Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression
J Immunol, 209 (10), 2042-2053
DOI 10.4049/jimmunol.2200144, PubMed 36426942 -
Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
Cancers (Basel), 14 (22)
DOI 10.3390/cancers14225603, PubMed 36428697 -
Super-resolution re-scan second harmonic generation microscopy
Proc Natl Acad Sci U S A, 119 (47), e2214662119
DOI 10.1073/pnas.2214662119, PubMed 36375085 -
ER-endosome contacts master the ins and outs of secretory endosomes
J Cell Biol, 221 (12)
DOI 10.1083/jcb.202210033, PubMed 36355088 -
A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT)
Front Oncol, 12, 1031232
DOI 10.3389/fonc.2022.1031232, PubMed 36439452 -
SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7
Front Immunol, 13, 994790
DOI 10.3389/fimmu.2022.994790, PubMed 36439103 -
Piezo1 activation by stretching of uterine myometrium supports pregnancy and prevents preterm labour
J Physiol, 601 (4), 719-721
DOI 10.1113/JP283810, PubMed 36266732 -
Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis
Ther Adv Med Oncol, 14, 17588359221133171
DOI 10.1177/17588359221133171, PubMed 36339929 -
Approach to a patient with "double refractory" chronic lymphocytic leukemia: "Double, double toil and trouble" (Shakespeare)
Am J Hematol, 97 Suppl 2, S19-S25
DOI 10.1002/ajh.26682, PubMed 36125036 -
Spatial genomics maps the structure, nature and evolution of cancer clones
Nature, 611 (7936), 594-602
DOI 10.1038/s41586-022-05425-2, PubMed 36352222 -
Small Interfering RNA Delivery Into Primary Human Natural Killer Cells for Functional Gene Analyses
Curr Protoc, 2 (11), e613
DOI 10.1002/cpz1.613, PubMed 36440989 -
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
J Immunother Cancer, 10 (11)
DOI 10.1136/jitc-2022-005577, PubMed 36319065 -
Hopes on immunotherapy targeting B7-H3 in neuroblastoma
Transl Oncol, 27, 101580
DOI 10.1016/j.tranon.2022.101580, PubMed 36327699 -
Fluid-sensitive migration mechanisms predict association between metastasis and high interstitial fluid pressure in pancreatic cancer
J Biomech, 145, 111362
DOI 10.1016/j.jbiomech.2022.111362, PubMed 36368256 -
"Double-punch" strategy against triple-negative breast cancer via a synergistic therapy of magneto-mechanical force enhancing NIR-II hypothermal ablation
Biomaterials, 291, 121868
DOI 10.1016/j.biomaterials.2022.121868, PubMed 36332286 -
Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development
Biochem J, 479 (20), 2219-2260
DOI 10.1042/BCJ20210233, PubMed 36305711 -
Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells
Front Oncol, 12, 981332
DOI 10.3389/fonc.2022.981332, PubMed 36387237 -
Treatment Characteristics and Real-World Progression-Free Survival in Patients With Unresectable Stage III NSCLC Who Received Durvalumab After Chemoradiotherapy: Findings From the PACIFIC-R Study
J Thorac Oncol, 18 (2), 181-193
DOI 10.1016/j.jtho.2022.10.003, PubMed 36307040 -
Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
Hum Mutat, 43 (12), 1921-1944
DOI 10.1002/humu.24449, PubMed 35979650 -
The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
Nat Commun, 13 (1), 6283
DOI 10.1038/s41467-022-33933-2, PubMed 36270994 -
Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
Cancer Rep (Hoboken), 6 (2), e1736
DOI 10.1002/cnr2.1736, PubMed 36251678 -
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Clin Cancer Res, 28 (20), 4444-4455
DOI 10.1158/1078-0432.CCR-22-1221, PubMed 35998013 -
Is HLA type a possible cancer risk modifier in Lynch syndrome?
Int J Cancer, 152 (10), 2024-2031
DOI 10.1002/ijc.34312, PubMed 36214792 -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
Br J Cancer, 127 (12), 2227-2233
DOI 10.1038/s41416-022-02004-0, PubMed 36229579 -
Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection
EMBO J, 41 (23), e111289
DOI 10.15252/embj.2022111289, PubMed 36221902 -
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance
Nat Commun, 13 (1), 5818
DOI 10.1038/s41467-022-33544-x, PubMed 36207323 -
Improved survival after single-unit cord blood transplantation using fludarabine and melphalan-based reduced-intensity conditioning for malignant lymphoma: impact of melphalan dose and graft-versus-host disease prophylaxis with mycophenolate mofetil
Ann Hematol, 101 (12), 2743-2757
DOI 10.1007/s00277-022-04990-w, PubMed 36195679 -
Development of a High-Affinity Antibody against the Tumor-Specific and Hyperactive 611-p95HER2 Isoform
Cancers (Basel), 14 (19)
DOI 10.3390/cancers14194859, PubMed 36230782 -
Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer
Eur Urol Open Sci, 45, 68-75
DOI 10.1016/j.euros.2022.09.002, PubMed 36353660 -
Corrigendum: Circulating T cell activation and exhaustion markers are associated with radiation pneumonitis and poor survival in non-small-cell lung cancer
Front Immunol, 13, 1051156
DOI 10.3389/fimmu.2022.1051156, PubMed 36263024 -
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
Hered Cancer Clin Pract, 20 (1), 36
DOI 10.1186/s13053-022-00241-1, PubMed 36182917 -
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
Genet Med, 24 (10), 2208
DOI 10.1016/j.gim.2022.08.005, PubMed 36205748 -
Plasma RNA profiling unveils transcriptional signatures associated with resistance to osimertinib in EGFR T790M positive non-small cell lung cancer patients
Transl Lung Cancer Res, 11 (10), 2064-2078
DOI 10.21037/tlcr-22-236, PubMed 36386450 -
The population genomic legacy of the second plague pandemic
Curr Biol, 32 (21), 4743-4751.e6
DOI 10.1016/j.cub.2022.09.023, PubMed 36182700 -
EnrichIntersect: an R package for custom set enrichment analysis and interactive visualization of intersecting sets
Bioinform Adv, 2 (1), vbac073
DOI 10.1093/bioadv/vbac073, PubMed 36699400 -
TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
FEBS J, 290 (4), 1096-1116
DOI 10.1111/febs.16628, PubMed 36111389 -
Target-specific compound selectivity for multi-target drug discovery and repurposing
Front Pharmacol, 13, 1003480
DOI 10.3389/fphar.2022.1003480, PubMed 36225560 -
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
Trends Pharmacol Sci, 43 (11), 973-985
DOI 10.1016/j.tips.2022.08.009, PubMed 36163057 -
BladMetrix: a novel urine DNA methylation test with high accuracy for detection of bladder cancer in hematuria patients
Clin Epigenetics, 14 (1), 115
DOI 10.1186/s13148-022-01335-2, PubMed 36115961 -
Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment
ESMO Open, 7 (5), 100588
DOI 10.1016/j.esmoop.2022.100588, PubMed 36116420 -
ER as master regulator of membrane trafficking and organelle function
J Cell Biol, 221 (10)
DOI 10.1083/jcb.202205135, PubMed 36108241 -
Risk of recurrence after chemoradiotherapy identified by multimodal MRI and 18F-FDG-PET/CT in locally advanced cervical cancer
Radiother Oncol, 176, 17-24
DOI 10.1016/j.radonc.2022.09.002, PubMed 36113778 -
Multifunctional Modulation of High-Performance Znx Fe3-x O4 Nanoparticles by Precisely Tuning the Zinc Doping Content
Small, 18 (42), e2201669
DOI 10.1002/smll.202201669, PubMed 36101918 -
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
Cancer Cell, 40 (9), 1027-1043.e9
DOI 10.1016/j.ccell.2022.08.005, PubMed 36099881 -
All-trans retinoic acid enhances the anti-tumour effects of fimaporfin-based photodynamic therapy
Biomed Pharmacother, 155, 113678
DOI 10.1016/j.biopha.2022.113678, PubMed 36108391 -
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
Br J Cancer, 127 (11), 1939-1953
DOI 10.1038/s41416-022-01973-6, PubMed 36097178 -
Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
J Transl Med, 20 (1), 419
DOI 10.1186/s12967-022-03624-z, PubMed 36089578 -
Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk
Cancer Epidemiol Biomarkers Prev, 31 (9), 1769-1779
DOI 10.1158/1055-9965.EPI-22-0123, PubMed 35700037 -
Whole exome sequencing of high-risk neuroblastoma identifies novel non-synonymous variants
PLoS One, 17 (8), e0273280
DOI 10.1371/journal.pone.0273280, PubMed 36037157 -
Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour
Br J Cancer, 127 (10), 1793-1798
DOI 10.1038/s41416-022-01959-4, PubMed 36030294 -
A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV
Nucleic Acids Res, 50 (15), e89
DOI 10.1093/nar/gkac434, PubMed 35641102 -
PHLPP1 regulates CFTR activity and lumen expansion through AMPK
Development, 149 (20)
DOI 10.1242/dev.200955, PubMed 35997536 -
Determining drug dose in the era of targeted therapies: playing it (un)safe?
Blood Cancer J, 12 (8), 123
DOI 10.1038/s41408-022-00720-7, PubMed 35999205 -
5-ALA Is a Potent Lactate Dehydrogenase Inhibitor but Not a Substrate: Implications for Cell Glycolysis and New Avenues in 5-ALA-Mediated Anticancer Action
Cancers (Basel), 14 (16)
DOI 10.3390/cancers14164003, PubMed 36010996 -
Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
Commun Biol, 5 (1), 834
DOI 10.1038/s42003-022-03559-7, PubMed 35982125 -
RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
NPJ Breast Cancer, 8 (1), 94
DOI 10.1038/s41523-022-00465-3, PubMed 35974007 -
Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells
Sci Rep, 12 (1), 13796
DOI 10.1038/s41598-022-18118-7, PubMed 35963891 -
Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
Genome Med, 14 (1), 86
DOI 10.1186/s13073-022-01090-2, PubMed 35948919 -
Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight
Acta Physiol (Oxf), 236 (4), e13862
DOI 10.1111/apha.13862, PubMed 36377504 -
An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia
Leukemia, 36 (10), 2384-2395
DOI 10.1038/s41375-022-01662-6, PubMed 35945345 -
Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
Int J Cancer, 152 (5), 945-951
DOI 10.1002/ijc.34226, PubMed 35880692 -
Differential Expression of miRNAs and Their Predicted Target Genes Indicates That Gene Expression in Atlantic Salmon Gill Is Post-Transcriptionally Regulated by miRNAs in the Parr-Smolt Transformation and Adaptation to Sea Water
Int J Mol Sci, 23 (15)
DOI 10.3390/ijms23158831, PubMed 35955964 -
Cost-effectiveness of molecularly matched off-label therapies for end-stage cancer - the MetAction precision medicine study
Acta Oncol, 61 (8), 955-962
DOI 10.1080/0284186X.2022.2098053, PubMed 35943168 -
Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants
Nature, 608 (7922), E20
DOI 10.1038/s41586-022-05097-y, PubMed 35840685 -
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica, 107 (8), 1994-1998
DOI 10.3324/haematol.2021.280393, PubMed 35236056 -
On the surface-to-bulk partition of proteins in extracellular vesicles
Colloids Surf B Biointerfaces, 218, 112728
DOI 10.1016/j.colsurfb.2022.112728, PubMed 35969923 -
Tissue-specific identification of multi-omics features for pan-cancer drug response prediction
iScience, 25 (8), 104767
DOI 10.1016/j.isci.2022.104767, PubMed 35992090 -
Rank-based Bayesian variable selection for genome-wide transcriptomic analyses
Stat Med, 41 (23), 4532-4553
DOI 10.1002/sim.9524, PubMed 35844145 -
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045 -
Ras-Related Protein Rab-32 and Thrombospondin 1 Confer Resistance to the EGFR Tyrosine Kinase Inhibitor Osimertinib by Activating Focal Adhesion Kinase in Non-Small Cell Lung Cancer
Cancers (Basel), 14 (14)
DOI 10.3390/cancers14143430, PubMed 35884490 -
Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
Front Immunol, 13, 875152
DOI 10.3389/fimmu.2022.875152, PubMed 35911763 -
Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure
Neurotoxicology, 92, 33-48
DOI 10.1016/j.neuro.2022.07.001, PubMed 35835329 -
An Experimental Generator for Production of High-Purity 212Pb for Use in Radiopharmaceuticals
J Nucl Med, 64 (1), 173-176
DOI 10.2967/jnumed.122.264009, PubMed 35798556 -
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056 -
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples
Nucleic Acids Res, 50 (W1), W739-W743
DOI 10.1093/nar/gkac382, PubMed 35580060 -
Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
J Control Release, 349, 1
DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388 -
DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
Breast Cancer Res, 24 (1), 43
DOI 10.1186/s13058-022-01537-9, PubMed 35751095 -
Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer
Mol Ther Oncolytics, 26, 189-206
DOI 10.1016/j.omto.2022.06.007, PubMed 35860008 -
In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
Mol Oncol, 16 (15), 2810-2822
DOI 10.1002/1878-0261.13225, PubMed 35574900 -
Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
Clin Epigenetics, 14 (1), 77
DOI 10.1186/s13148-022-01287-7, PubMed 35701814 -
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Cancer Res Commun, 2 (6), 434-446
DOI 10.1158/2767-9764.CRC-21-0100, PublikaID 411 -
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Cancer Res Commun, 2 (6), 434-446
DOI 10.1158/2767-9764.CRC-21-0100, PubMed 36923555 -
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression
Nat Biotechnol, 40 (11), 1624-1633
DOI 10.1038/s41587-022-01342-x, PubMed 35697807 -
Photochemical Internalization of Gemcitabine Is Safe and Effective in Locally Advanced Inoperable Cholangiocarcinoma
Oncologist, 27 (6), 430-e433
DOI 10.1093/oncolo/oyab074, PubMed 35675633 -
Factors Influencing the Therapeutic Efficacy of the PSMA Targeting Radioligand 212Pb-NG001
Cancers (Basel), 14 (11)
DOI 10.3390/cancers14112784, PubMed 35681766 -
T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation
Br J Haematol, 198 (3), 556-573
DOI 10.1111/bjh.18285, PubMed 35655388 -
The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?
Bioessays, 44 (7), e2200065
DOI 10.1002/bies.202200065, PubMed 35655365 -
The Karolinska KI/K COVID-19 Immune Atlas: An open resource for immunological research and educational purposes
Scand J Immunol, 96 (1), e13195 (in press)
DOI 10.1111/sji.13195, PubMed 35652743 -
Systematic review of computational methods for drug combination prediction
Comput Struct Biotechnol J, 20, 2807-2814
DOI 10.1016/j.csbj.2022.05.055, PubMed 35685365 -
Impact of KIR-ligand mismatch on pediatric T-cell acute lymphoblastic leukemia in unrelated cord blood transplantation
Transplant Cell Ther, 28 (9), 598.e1-598.e8
DOI 10.1016/j.jtct.2022.05.037, PubMed 35660064 -
Osimertinib in non-small cell lung cancer with uncommon EGFR-mutations: a post-hoc subgroup analysis with pooled data from two phase II clinical trials
Transl Lung Cancer Res, 11 (6), 953-963
DOI 10.21037/tlcr-21-995, PubMed 35832438 -
Comparative analysis of the molecular subtype landscape in canine and human mammary gland tumors
J Mammary Gland Biol Neoplasia, 27 (2), 171-183
DOI 10.1007/s10911-022-09523-9, PubMed 35932380 -
Expansion, persistence, and efficacy of donor memory-like NK cells infused for posttransplant relapse
J Clin Invest, 132 (11)
DOI 10.1172/JCI154334, PubMed 35349491 -
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
Leukemia, 36 (7), 1887-1897
DOI 10.1038/s41375-022-01597-y, PubMed 35643867 -
Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
Front Oncol, 12, 873516
DOI 10.3389/fonc.2022.873516, PubMed 35692804 -
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
Toxins (Basel), 14 (5)
DOI 10.3390/toxins14050360, PubMed 35622606 -
Evaluation of statistical approaches for association testing in noisy drug screening data
BMC Bioinformatics, 23 (1), 188
DOI 10.1186/s12859-022-04693-z, PubMed 35585485 -
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 186, 114326
DOI 10.1016/j.addr.2022.114326, PubMed 35588953 -
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909 -
Capture Rate of V(D)J Sequencing for Minimal Residual Disease Detection in Multiple Myeloma
Clin Cancer Res, 28 (10), 2160-2166
DOI 10.1158/1078-0432.CCR-20-2995, PubMed 35553646 -
Autophagy power expands: fuse those cells!
EMBO J, 41 (12), e111424
DOI 10.15252/embj.2022111424, PubMed 35561082 -
Improved outcomes of single-unit cord blood transplantation for acute myeloid leukemia by killer immunoglobulin-like receptor 2DL1-ligand mismatch
Bone Marrow Transplant, 57 (7), 1171-1179
DOI 10.1038/s41409-022-01700-y, PubMed 35538140 -
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553 -
A national precision cancer medicine implementation initiative for Norway
Nat Med, 28 (5), 885-887
DOI 10.1038/s41591-022-01777-4, PubMed 35513529 -
Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
J Immunother Cancer, 10 (5)
DOI 10.1136/jitc-2021-004345, PubMed 35613827 -
Expression Analysis in Atlantic Salmon Liver Reveals miRNAs Associated with Smoltification and Seawater Adaptation
Biology (Basel), 11 (5)
DOI 10.3390/biology11050688, PubMed 35625416 -
Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma
Front Oncol, 12, 873532
DOI 10.3389/fonc.2022.873532, PubMed 35574381 -
Anti-CD37 radioimmunotherapy with 177Lu-NNV003 synergizes with the PARP inhibitor olaparib in treatment of non-Hodgkin's lymphoma in vitro
PLoS One, 17 (4), e0267543
DOI 10.1371/journal.pone.0267543, PubMed 35486574 -
Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer
Mod Pathol, 35 (9), 1236-1246
DOI 10.1038/s41379-022-01086-8, PubMed 35484226 -
Inhibition of glioma development by doxorubicin-photochemical internalization generated macrophage vaccine: A survival study in rats
Photodiagnosis Photodyn Ther, 38, 102879
DOI 10.1016/j.pdpdt.2022.102879, PubMed 35489691 -
Tumor microenvironment as a metapopulation model: The effects of angiogenesis, emigration and treatment modalities
J Theor Biol, 545, 111147
DOI 10.1016/j.jtbi.2022.111147, PubMed 35489642 -
How CAR T Cells Breathe
Cells, 11 (9)
DOI 10.3390/cells11091454, PubMed 35563759 -
B7-H4 Immune Checkpoint Protein Affects Viability and Targeted Therapy of Renal Cancer Cells
Cells, 11 (9)
DOI 10.3390/cells11091448, PubMed 35563753 -
An optimized platform for efficient siRNA delivery into human NK cells
Eur J Immunol, 52 (7), 1190-1193
DOI 10.1002/eji.202149710, PubMed 35416292 -
Asporin, an extracellular matrix protein, is a beneficial regulator of cardiac remodeling
Matrix Biol, 110, 40-59
DOI 10.1016/j.matbio.2022.04.005, PubMed 35470068 -
Circulating tumour DNA and its clinical utility in predicting treatment response or survival in patients with metastatic colorectal cancer: a systematic review and meta-analysis
Br J Cancer, 127 (3), 500-513
DOI 10.1038/s41416-022-01816-4, PubMed 35440666 -
Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers
Epigenetics Chromatin, 15 (1), 13
DOI 10.1186/s13072-022-00444-9, PubMed 35440061 -
Serglycin Is Involved in TGF-β Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue
Front Oncol, 12, 868868
DOI 10.3389/fonc.2022.868868, PubMed 35494005 -
Structural Requirements for the Binding of a Peptide to Prohibitins on the Cell Surface of Monocytes/Macrophages
Int J Mol Sci, 23 (8)
DOI 10.3390/ijms23084282, PubMed 35457098 -
Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix
Front Mol Biosci, 9, 763750
DOI 10.3389/fmolb.2022.763750, PubMed 35495628 -
Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
Cell Mol Life Sci, 79 (4), 220
DOI 10.1007/s00018-022-04251-z, PubMed 35368213 -
NRF2 drives an oxidative stress response predictive of breast cancer
Free Radic Biol Med, 184, 170-184
DOI 10.1016/j.freeradbiomed.2022.03.029, PubMed 35381325 -
The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray Resource
Cancer Epidemiol Biomarkers Prev, 31 (4), 715-727
DOI 10.1158/1055-9965.EPI-21-0600, PubMed 35131885 -
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells
FASEB J, 36 (4), e22218
DOI 10.1096/fj.202101657R, PubMed 35218567 -
ALK Inhibitors in Patients With ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series
JCO Precis Oncol, 6 (1), e2200015
DOI 10.1200/PO.22.00015, PubMed 35476549 -
Scattering-type Scanning Near-Field Optical Microscopy of Polymer-Coated Gold Nanoparticles
ACS Omega, 7 (13), 11353-11362
DOI 10.1021/acsomega.2c00410, PubMed 35415325 -
Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancer
NAR Cancer, 4 (1), zcac008
DOI 10.1093/narcan/zcac008, PubMed 35350772 -
A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients
Br J Cancer, 127 (2), 321-328
DOI 10.1038/s41416-022-01782-x, PubMed 35332267 -
AXL inhibition improves BRAF-targeted treatment in melanoma
Sci Rep, 12 (1), 5076
DOI 10.1038/s41598-022-09078-z, PubMed 35332208 -
Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
Br J Haematol, 197 (6), 697-708
DOI 10.1111/bjh.18149, PubMed 35254660 -
3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
Bio Protoc, 12 (6), e4360
DOI 10.21769/BioProtoc.4360, PubMed 35434191 -
Need for more focus on lipid species in studies of biological and model membranes
Prog Lipid Res, 86, 101160
DOI 10.1016/j.plipres.2022.101160, PubMed 35288150 -
Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data
Nat Commun, 13 (1), 1246
DOI 10.1038/s41467-022-28803-w, PubMed 35273156 -
Chasing neoantigens; invite naïve T cells to the party
Curr Opin Immunol, 75, 102172
DOI 10.1016/j.coi.2022.102172, PubMed 35279483 -
What are the current challenges for machine learning in drug discovery and repurposing?
Expert Opin Drug Discov, 17 (5), 423-425
DOI 10.1080/17460441.2022.2050694, PubMed 35255749 -
Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
Oncotarget, 13, 508-517
DOI 10.18632/oncotarget.28209, PubMed 35284037 -
Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
Cancers (Basel), 14 (5)
DOI 10.3390/cancers14051326, PubMed 35267636 -
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
Curr Opin Cell Biol, 75, 102062
DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976 -
Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
STAR Protoc, 3 (1), 101210
DOI 10.1016/j.xpro.2022.101210, PubMed 35265859 -
Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy
Neoplasia, 26, 100779
DOI 10.1016/j.neo.2022.100779, PubMed 35247801 -
miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
Breast Cancer (Dove Med Press), 14, 25-39
DOI 10.2147/BCTT.S338404, PubMed 35256859 -
Tryptophan depletion results in tryptophan-to-phenylalanine substitutants
Nature, 603 (7902), 721-727
DOI 10.1038/s41586-022-04499-2, PubMed 35264796 -
Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
Mol Oncol, 16 (6), 1241-1258
DOI 10.1002/1878-0261.13191, PubMed 35148457 -
Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
Curr Opin Cell Biol, 75, 102064
DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373 -
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
Autophagy, 18 (11), 2547-2560
DOI 10.1080/15548627.2022.2039535, PubMed 35220892 -
Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
J Genet Couns, 31 (4), 949-955
DOI 10.1002/jgc4.1567, PubMed 35218578 -
Response to Chambuso et al
Genet Med, 24 (5), 1151
DOI 10.1016/j.gim.2022.01.005, PubMed 35216900 -
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
Cancer Gene Ther, 29 (8-9), 1276-1284
DOI 10.1038/s41417-022-00444-7, PubMed 35194199 -
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
JCI Insight, 7 (4)
DOI 10.1172/jci.insight.155309, PubMed 35050902 -
Waves of sumoylation support transcription dynamics during adipocyte differentiation
Nucleic Acids Res, 50 (3), 1351-1369
DOI 10.1093/nar/gkac027, PubMed 35100417 -
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Cell Rep, 38 (10), 110503
DOI 10.1016/j.celrep.2022.110503, PubMed 35235832 -
Transautophagy: Research and Translation of Autophagy Knowledge 2020
Oxid Med Cell Longev, 2022, 9792132
DOI 10.1155/2022/9792132, PubMed 35340207 -
miR-486-5p expression is regulated by DNA methylation in osteosarcoma
BMC Genomics, 23 (1), 142
DOI 10.1186/s12864-022-08346-6, PubMed 35172717 -
Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
J Infect Dis, 225 (4), 661-674
DOI 10.1093/infdis/jiaa714, PubMed 33216130 -
miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
Mol Oncol, 16 (6), 1402-1419
DOI 10.1002/1878-0261.13184, PubMed 35064630 -
ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
J Cell Sci, 135 (4)
DOI 10.1242/jcs.259138, PubMed 35099014 -
FGF-FGFR signaling promotes the development of invasive cervical cancer
FEBS J, 289 (12), 3419-3421
DOI 10.1111/febs.16384, PubMed 35146913 -
Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
Elife, 11
DOI 10.7554/eLife.71035, PubMed 35147498 -
Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
J Clin Med, 11 (3)
DOI 10.3390/jcm11030879, PubMed 35160330 -
Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
Sci Rep, 12 (1), 2056
DOI 10.1038/s41598-022-05991-5, PubMed 35136137 -
Extracellular Vesicles as Novel Players in Kidney Disease
J Am Soc Nephrol, 33 (3), 467-471
DOI 10.1681/ASN.2021091232, PubMed 35131841 -
Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
EMBO Rep, 23 (3), e54431
DOI 10.15252/embr.202154431, PubMed 35156749 -
Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
Blood, 139 (5), 704-716
DOI 10.1182/blood.2021013233, PubMed 34699594 -
Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
Cells, 11 (3)
DOI 10.3390/cells11030522, PubMed 35159330 -
Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
Int J Mol Sci, 23 (3)
DOI 10.3390/ijms23031293, PubMed 35163213 -
Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers
Cancers (Basel), 14 (3)
DOI 10.3390/cancers14030571, PubMed 35158839 -
Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
Biomedicines, 10 (2)
DOI 10.3390/biomedicines10020232, PubMed 35203441 -
Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
Gynecol Oncol, 164 (3), 514-521
DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280 -
Artificial intelligence for drug response prediction in disease models
Brief Bioinform, 23 (1)
DOI 10.1093/bib/bbab450, PubMed 34655289 -
Final efficacy and safety data, and exploratory molecular profiling from the phase III ALUR study of alectinib versus chemotherapy in crizotinib-pretreated ALK-positive non-small-cell lung cancer
ESMO Open, 7 (1), 100333
DOI 10.1016/j.esmoop.2021.100333, PubMed 35042152 -
STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
Am J Cancer Res, 12 (1), 327-336
PubMed 35141021 -
A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
NAR Cancer, 4 (1), zcab051
DOI 10.1093/narcan/zcab051, PubMed 35047825 -
Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
Cancers (Basel), 14 (2)
DOI 10.3390/cancers14020421, PubMed 35053583 -
HLA-independent T cell receptors for targeting tumors with low antigen density
Nat Med, 28 (2), 345-352
DOI 10.1038/s41591-021-01621-1, PubMed 35027758 -
Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
Biology (Basel), 11 (1)
DOI 10.3390/biology11010130, PubMed 35053128 -
Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Eur Urol, 81 (4), 431
DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159 -
Incidence of breast cancer subtypes in immigrant and non-immigrant women in Norway
Breast Cancer Res, 24 (1), 4
DOI 10.1186/s13058-021-01498-5, PubMed 35012613 -
GAK and PRKCD kinases regulate basal mitophagy
Autophagy, 18 (2), 467-469
DOI 10.1080/15548627.2021.2015154, PubMed 35001811 -
Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
Ann N Y Acad Sci, 1510 (1), 79-99
DOI 10.1111/nyas.14745, PubMed 35000205 -
Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC
Mol Oncol, 16 (3), 717-731
DOI 10.1002/1878-0261.13167, PubMed 34932879 -
MirGeneDB 2.1: toward a complete sampling of all major animal phyla
Nucleic Acids Res, 50 (D1), D204-D210
DOI 10.1093/nar/gkab1101, PubMed 34850127 -
Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Breast Cancer Res, 24 (1), 2
DOI 10.1186/s13058-021-01484-x, PubMed 34983606 -
Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
JAMA Netw Open, 5 (1), e2145230
DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602 -
Sonochemical Internalization of Bleomycin Inhibits Adenocarcinoma Breast Tumor Development in an Orthotopic Rat Model
J Environ Pathol Toxicol Oncol, 41 (2), 25-35
DOI 10.1615/JEnvironPatholToxicolOncol.2021040536, PubMed 35695649 -
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells
J Immunother Cancer, 10 (1)
DOI 10.1136/jitc-2021-002500, PubMed 35078921 -
Measuring Autophagic Cargo Flux with Keima-Based Probes
Methods Mol Biol, 2445, 99-115
DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988 -
Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells
Methods Mol Biol, 2449, 327-348
DOI 10.1007/978-1-0716-2095-3_14, PubMed 35507270 -
Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
J Acquir Immune Defic Syndr, 89 (1), 77-86
DOI 10.1097/QAI.0000000000002817, PubMed 34878437 -
EGFR-mutation testing and TKI treatment patterns in locally advanced and metastatic NSCLC in Norway - A nationwide retrospective cohort study
Cancer Treat Res Commun, 33, 100636
DOI 10.1016/j.ctarc.2022.100636, PubMed 36155129 -
Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193
Publications 2021
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Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Sci Total Environ, 814, 152732
DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025 -
Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Cell Rep, 37 (13), 110186
DOI 10.1016/j.celrep.2021.110186, PubMed 34965431 -
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
Mol Oncol, 16 (12), 2312-2329
DOI 10.1002/1878-0261.13159, PubMed 34890102 -
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
mBio, 12 (6), e0334721
DOI 10.1128/mbio.03347-21, PubMed 34933447 -
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909 -
Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
Mol Oncol, 16 (5), 1153-1170
DOI 10.1002/1878-0261.13153, PubMed 34861096 -
Rapid genome editing by CRISPR-Cas9-POLD3 fusion
Elife, 10
DOI 10.7554/eLife.75415, PubMed 34898428 -
A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
J Clin Immunol, 42 (2), 404-420
DOI 10.1007/s10875-021-01189-y, PubMed 34893945 -
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
Br J Cancer, 126 (5), 726-735
DOI 10.1038/s41416-021-01620-6, PubMed 34887523 -
Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets
Front Cell Dev Biol, 9, 811297
DOI 10.3389/fcell.2021.811297, PubMed 34957126 -
Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
Cells, 10 (12)
DOI 10.3390/cells10123432, PubMed 34943939 -
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nat Biotechnol, 40 (4), 488-498
DOI 10.1038/s41587-021-01089-x, PubMed 34873326 -
Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
Sci Rep, 11 (1), 23463
DOI 10.1038/s41598-021-02820-z, PubMed 34873230 -
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693 -
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228 -
Survival Trends of Right- and Left-Sided Colon Cancer across Four Decades: A Norwegian Population-Based Study
Cancer Epidemiol Biomarkers Prev, 31 (2), 342-351
DOI 10.1158/1055-9965.EPI-21-0555, PubMed 34853022 -
Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
Appl. Sci.-Basel, 11 (24), 11936
DOI 10.3390/app112411936 -
Correction to: ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
Ann Surg Oncol, 28 (Suppl 3), 873
DOI 10.1245/s10434-021-09939-3, PubMed 33829360 -
PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress
Cancer Immunol Res, 10 (2), 228-244
DOI 10.1158/2326-6066.CIR-20-1023, PubMed 34853030 -
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
Genet Med, 24 (1), 119-129
DOI 10.1016/j.gim.2021.08.016, PubMed 34906479 -
Publisher Correction: Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Nat Commun, 12 (1), 7073
DOI 10.1038/s41467-021-27175-x, PubMed 34848706 -
A Novel Single-Step-Labeled 212Pb-CaCO3 Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice
Materials (Basel), 14 (23)
DOI 10.3390/ma14237130, PubMed 34885283 -
A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
Blood Adv, 5 (22), 4771-4782
DOI 10.1182/bloodadvances.2021004777, PubMed 34543384 -
Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients
Br J Cancer, 126 (3), 492-501
DOI 10.1038/s41416-021-01598-1, PubMed 34811506 -
Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
Br J Cancer, 126 (3), 331-350
DOI 10.1038/s41416-021-01610-8, PubMed 34811504 -
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Nat Commun, 12 (1), 6774
DOI 10.1038/s41467-021-27029-6, PubMed 34811370 -
Adaptation to hypoxia in Drosophila melanogaster requires autophagy
Autophagy, 18 (4), 909-920
DOI 10.1080/15548627.2021.1991191, PubMed 34793268 -
The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
Front Immunol, 12, 764596
DOI 10.3389/fimmu.2021.764596, PubMed 34868011 -
Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
Cancer Discov, 12 (2), 388-401
DOI 10.1158/2159-8290.CD-21-0410, PubMed 34789538 -
MapToCleave: High-throughput profiling of microRNA biogenesis in living cells
Cell Rep, 37 (7), 110015
DOI 10.1016/j.celrep.2021.110015, PubMed 34788611 -
AKIP1 promotes tumor progression by cancer-related pathways and predicts prognosis in tongue squamous cell carcinoma
Am J Transl Res, 13 (11), 12338-12351
PubMed 34956456 -
A scalable solver for a stochastic, hybrid cellular automaton model of personalized breast cancer therapy
Int J Numer Method Biomed Eng, 38 (1), e3542
DOI 10.1002/cnm.3542, PubMed 34716985 -
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750 -
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
Nat Commun, 12 (1), 6577
DOI 10.1038/s41467-021-26775-x, PubMed 34772942 -
(Pro)renin Receptor Is a Novel Independent Prognostic Marker in Invasive Urothelial Carcinoma of the Bladder
Cancers (Basel), 13 (22)
DOI 10.3390/cancers13225642, PubMed 34830803 -
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317 -
Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle
PLoS Genet, 17 (11), e1009907
DOI 10.1371/journal.pgen.1009907, PubMed 34752468 -
Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation
Proc Natl Acad Sci U S A, 118 (45)
DOI 10.1073/pnas.2100050118, PubMed 34737229 -
Light-controlled elimination of PD-L1+ cells
J Photochem Photobiol B, 225, 112355
DOI 10.1016/j.jphotobiol.2021.112355, PubMed 34768077 -
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
Autophagy, 18 (7), 1486-1502
DOI 10.1080/15548627.2021.1988359, PubMed 34740308 -
Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging
Bioinformatics, 37 (21), 3796-3804
DOI 10.1093/bioinformatics/btab569, PubMed 34358288 -
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021 -
bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
Brief Bioinform, 22 (6)
DOI 10.1093/bib/bbab251, PubMed 34308471 -
COVID-19 in patients with CLL: improved survival outcomes and update on management strategies
Blood, 138 (18), 1768-1773
DOI 10.1182/blood.2021011841, PubMed 34297826 -
Correction: Sioud et al. Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Monolayer and Multicellular Tumor Spheroid Models. Cancers 2021, 13, 3356
Cancers (Basel), 13 (21)
DOI 10.3390/cancers13215513, PubMed 34771754 -
The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
Nat Mach Intell, 3 (11), 936-944
DOI 10.1038/s42256-021-00413-z, PubMed 37396030 -
Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms
Nat Cancer, 2 (11), 1224-1242
DOI 10.1038/s43018-021-00259-9, PubMed 34870237 -
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
mBio, 12 (6), e03347-21 -
Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
Br J Cancer, 126 (1), 48-56
DOI 10.1038/s41416-021-01586-5, PubMed 34671130 -
GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Nat Commun, 12 (1), 6101
DOI 10.1038/s41467-021-26331-7, PubMed 34671015 -
Tailored graphical lasso for data integration in gene network reconstruction
BMC Bioinformatics, 22 (1), 498
DOI 10.1186/s12859-021-04413-z, PubMed 34654363 -
Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
BMC Cancer, 21 (1), 1089
DOI 10.1186/s12885-021-08811-7, PubMed 34625038 -
Advances in immune therapies in hematological malignancies
J Intern Med, 292 (2), 205-220
DOI 10.1111/joim.13395, PubMed 34624160 -
Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
Front Immunol, 12, 744155
DOI 10.3389/fimmu.2021.744155, PubMed 34691047 -
Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Cancer Med, 10 (23), 8604-8613
DOI 10.1002/cam4.4334, PubMed 34612023 -
Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead
Eur Urol, 81 (1), 127-128
DOI 10.1016/j.eururo.2021.09.025, PubMed 34625312 -
Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells
Sci Signal, 14 (703), eabc8579
DOI 10.1126/scisignal.abc8579, PubMed 34609894 -
The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients
J Immunol, 207 (10), 2501-2511
DOI 10.4049/jimmunol.2001103, PubMed 34607938 -
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Sci Total Environ, 807 (Pt 1), 150697
DOI 10.1016/j.scitotenv.2021.150697, PubMed 34610396 -
Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
J Immunother Cancer, 9 (10)
DOI 10.1136/jitc-2021-003109, PubMed 34711663 -
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Cancer Res, 81 (22), 5733-5744
DOI 10.1158/0008-5472.CAN-21-0061, PubMed 34593524 -
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
Cancer Cell, 39 (10), 1422-1437.e10
DOI 10.1016/j.ccell.2021.08.011, PubMed 34597589 -
Lack of cross-resistance between non-steroidal and steroidal aromatase inhibitors in breast cancer patients: the potential role of the adipokine leptin
Breast Cancer Res Treat, 190 (3), 435-449
DOI 10.1007/s10549-021-06399-x, PubMed 34554372 -
Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods
Front Oncol, 11, 722773
DOI 10.3389/fonc.2021.722773, PubMed 34621674 -
Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Trials, 22 (1), 642
DOI 10.1186/s13063-021-05587-w, PubMed 34544470 -
Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
Biomacromolecules, 22 (10), 4169-4180
DOI 10.1021/acs.biomac.1c00662, PubMed 34542998 -
Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
NPJ Syst Biol Appl, 7 (1), 36
DOI 10.1038/s41540-021-00195-5, PubMed 34535676 -
Progress and challenges in mass spectrometry-based analysis of antibody repertoires
Trends Biotechnol, 40 (4), 463-481
DOI 10.1016/j.tibtech.2021.08.006, PubMed 34535228 -
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Cell Stem Cell, 28 (12), 2062-2075.e5
DOI 10.1016/j.stem.2021.08.013, PubMed 34525347 -
Squamous cell carcinoma of the ear treated by photochemical internalization
Photodiagnosis Photodyn Ther, 36, 102528
DOI 10.1016/j.pdpdt.2021.102528, PubMed 34509683 -
Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression
NPJ Breast Cancer, 7 (1), 118
DOI 10.1038/s41523-021-00329-2, PubMed 34508103 -
Characterization of mechanisms positioning costimulatory complexes in immune synapses
iScience, 24 (10), 103100
DOI 10.1016/j.isci.2021.103100, PubMed 34622155 -
Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up
Int J Cancer, 150 (1), 100-111
DOI 10.1002/ijc.33768, PubMed 34449877 -
Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
J Transl Med, 19 (1), 384
DOI 10.1186/s12967-021-03062-3, PubMed 34496878 -
[Immunotherapy for malignant pleural mesothelioma]
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0503, PubMed 34505475 -
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
Nat Commun, 12 (1), 5307
DOI 10.1038/s41467-021-25624-1, PubMed 34489465 -
Immunotherapy in malignant pleural mesothelioma
Tidsskr. Nor. Laegeforen., 141 (12), 1167-1169 -
Intracranial effect of osimertinib in relapsed EGFR-mutated T790M-positive and -negative non-small cell lung cancer patients: results from a phase II study
Acta Oncol, 60 (12), 1565-1571
DOI 10.1080/0284186X.2021.1973092, PubMed 34486915 -
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174456, PubMed 34503266 -
A man in his sixties with dyspnoea following immunotherapy
Tidsskr Nor Laegeforen, 141 (2021-12)
DOI 10.4045/tidsskr.21.0139, PubMed 34505469 -
Towards evidence-based personalised precision medicine for Lynch syndrome
Lancet Oncol, 22 (9), e383
DOI 10.1016/S1470-2045(21)00400-9, PubMed 34478667 -
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666 -
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667 -
Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor
Mol Oncol, 15 (11), 2958-2968
DOI 10.1002/1878-0261.13082, PubMed 34402187 -
"Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
FASEB J, 35 (9), e21750
DOI 10.1096/fj.202100025R, PubMed 34424568 -
Autophagy in major human diseases
EMBO J, 40 (19), e108863
DOI 10.15252/embj.2021108863, PubMed 34459017 -
Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
Cells, 10 (9)
DOI 10.3390/cells10092231, PubMed 34571880 -
Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma
Nat Commun, 12 (1), 5172
DOI 10.1038/s41467-021-25469-8, PubMed 34453055 -
The Prognostic Effect of KRAS Mutations in Non-Small Cell Lung Carcinoma Revisited: A Norwegian Multicentre Study
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174294, PubMed 34503114 -
Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412 -
Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy
Cancers (Basel), 13 (16)
DOI 10.3390/cancers13164162, PubMed 34439316 -
The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
BMC Cancer, 21 (1), 930
DOI 10.1186/s12885-021-08640-8, PubMed 34407780 -
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
Breast Cancer Res, 23 (1), 86
DOI 10.1186/s13058-021-01450-7, PubMed 34407845 -
RasV12; scrib-/- Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168873, PubMed 34445578 -
Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer
Am J Nucl Med Mol Imaging, 11 (4), 250-259
PubMed 34513278 -
Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168711, PubMed 34445425 -
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
Int J Cancer, 149 (11), 1955-1960
DOI 10.1002/ijc.33749, PubMed 34310709 -
Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465 -
Autophagy in healthy aging and disease
Nat Aging, 1 (8), 634-650
DOI 10.1038/s43587-021-00098-4, PubMed 34901876 -
Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
Clin Pharmacol Ther, 110 (4), 952-965
DOI 10.1002/cpt.2336, PubMed 34145575 -
Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells
Cancers (Basel), 13 (15)
DOI 10.3390/cancers13153790, PubMed 34359691 -
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
EMBO J, 40 (18), e107336
DOI 10.15252/embj.2020107336, PubMed 34309071 -
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia
NPJ Precis Oncol, 5 (1), 71
DOI 10.1038/s41698-021-00209-9, PubMed 34302041 -
Identification of 22 susceptibility loci associated with testicular germ cell tumors
Nat Commun, 12 (1), 4487
DOI 10.1038/s41467-021-24334-y, PubMed 34301922 -
Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements
Antioxidants (Basel), 10 (7)
DOI 10.3390/antiox10071149, PubMed 34356382 -
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
J Cell Sci, 134 (14)
DOI 10.1242/jcs.258495, PubMed 34109410 -
CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
Elife, 10
DOI 10.7554/eLife.63731, PubMed 34259627 -
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
NPJ Genom Med, 6 (1), 59
DOI 10.1038/s41525-021-00223-7, PubMed 34262039 -
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
Proc Natl Acad Sci U S A, 118 (28)
DOI 10.1073/pnas.2024596118, PubMed 34244439 -
Modeling drug combination effects via latent tensor reconstruction
Bioinformatics, 37 (Suppl_1), i93-i101
DOI 10.1093/bioinformatics/btab308, PubMed 34252952 -
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864 -
Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
Front Cell Infect Microbiol, 11, 669623
DOI 10.3389/fcimb.2021.669623, PubMed 34307194 -
Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
Front Immunol, 12, 682492
DOI 10.3389/fimmu.2021.682492, PubMed 34290704 -
Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
Cancers (Basel), 13 (13)
DOI 10.3390/cancers13133356, PubMed 34283089 -
Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response
Cancers (Basel), 13 (13)
DOI 10.3390/cancers13133325, PubMed 34283056 -
The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones
Appl. Sci.-Basel, 11 (13), 5762
DOI 10.3390/app11135762 -
First person - Kia Wee Tan
J. Cell Sci., 134 (14), jcs259055
DOI 10.1242/jcs.259055 -
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362 -
Characterizing the Quality of Insight by Interactions: A Case Study
IEEE Trans Vis Comput Graph, 27 (8), 3410-3424
DOI 10.1109/TVCG.2020.2977634, PubMed 32142444 -
Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
PLoS One, 16 (6), e0253828
DOI 10.1371/journal.pone.0253828, PubMed 34191854 -
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
Cell Rep, 35 (13), 109291
DOI 10.1016/j.celrep.2021.109291, PubMed 34192548 -
An improved in vitro photochemical internalization protocol for 3D spheroid cultures
Lasers Med Sci, 36 (8), 1567-1571
DOI 10.1007/s10103-021-03332-y, PubMed 34185168 -
No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
J Clin Med, 10 (13)
DOI 10.3390/jcm10132856, PubMed 34203177 -
Circulating Tumor Cell Persistence Associates with Long-Term Clinical Outcome to a Therapeutic Cancer Vaccine in Prostate Cancer
J Pers Med, 11 (7)
DOI 10.3390/jpm11070605, PubMed 34206815 -
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
Am J Hum Genet, 108 (7), 1190-1203
DOI 10.1016/j.ajhg.2021.05.013, PubMed 34146516 -
Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
Oncoimmunology, 10 (1), 1936757
DOI 10.1080/2162402X.2021.1936757, PubMed 34235003 -
What It Takes to Transform a T Cell
Cancer Res, 81 (12), 3160-3161
DOI 10.1158/0008-5472.CAN-21-0784, PubMed 34224376 -
Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
Prostate, 81 (12), 838-848
DOI 10.1002/pros.24180, PubMed 34125445 -
First international workshop of the ATM and cancer risk group (4-5 December 2019)
Fam Cancer, 21 (2), 211-227
DOI 10.1007/s10689-021-00248-y, PubMed 34125377 -
Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
Cells, 10 (6)
DOI 10.3390/cells10061476, PubMed 34204611 -
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
Int J Mol Sci, 22 (12)
DOI 10.3390/ijms22126309, PubMed 34208396 -
Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression
J Immunol Res, 2021, 9920234
DOI 10.1155/2021/9920234, PubMed 34195299 -
Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
Front Oncol, 11, 671629
DOI 10.3389/fonc.2021.671629, PubMed 34178659 -
A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
Bone Marrow Transplant, 56 (10), 2477-2488
DOI 10.1038/s41409-021-01356-0, PubMed 34108672 -
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer
JCI Insight, 6 (11)
DOI 10.1172/jci.insight.147617, PubMed 33886505 -
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia
J Med Chem, 64 (12), 8486-8509
DOI 10.1021/acs.jmedchem.1c00420, PubMed 34101461 -
Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
Cancers (Basel), 13 (11)
DOI 10.3390/cancers13112819, PubMed 34198773 -
EMT-Derived Alterations in Glutamine Metabolism Sensitize Mesenchymal Breast Cells to mTOR Inhibition
Mol Cancer Res, 19 (9), 1546-1558
DOI 10.1158/1541-7786.MCR-20-0962, PubMed 34088869 -
Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface
J Mol Biol, 433 (15), 167086
DOI 10.1016/j.jmb.2021.167086, PubMed 34089718 -
Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression
Front Genet, 12, 670749
DOI 10.3389/fgene.2021.670749, PubMed 34149812 -
Crowdsourced mapping of unexplored target space of kinase inhibitors
Nat Commun, 12 (1), 3307
DOI 10.1038/s41467-021-23165-1, PubMed 34083538 -
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
J Theor Biol, 526, 110787
DOI 10.1016/j.jtbi.2021.110787, PubMed 34087266 -
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
Neoplasia, 23 (6), 634-641
DOI 10.1016/j.neo.2021.05.012, PubMed 34107378 -
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
J Transl Med, 19 (1), 232
DOI 10.1186/s12967-021-02905-3, PubMed 34059094 -
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362 -
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
Cells, 10 (6)
DOI 10.3390/cells10061342, PubMed 34071546 -
Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: toxicity and changes in the proteome of breast, colon and prostate cancer cells
Nanotoxicology, 15 (7), 865-884
DOI 10.1080/17435390.2021.1924888, PubMed 34047629 -
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
Nat Commun, 12 (1), 3230
DOI 10.1038/s41467-021-23445-w, PubMed 34050156 -
European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
Br J Surg, 108 (5), 484-498
DOI 10.1002/bjs.11902, PubMed 34043773 -
Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
J Mol Biol, 433 (15), 167049
DOI 10.1016/j.jmb.2021.167049, PubMed 34052024 -
MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
Sci Rep, 11 (1), 10893
DOI 10.1038/s41598-021-90385-2, PubMed 34035375 -
The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
Toxins (Basel), 13 (6)
DOI 10.3390/toxins13060377, PubMed 34070659 -
Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers
Front Oncol, 11, 674731
DOI 10.3389/fonc.2021.674731, PubMed 34109123 -
Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion
Int J Cancer, 149 (6), 1247-1256
DOI 10.1002/ijc.33680, PubMed 33990967 -
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol, 28 (9), 5252-5262
DOI 10.1245/s10434-021-10022-0, PubMed 34019185 -
Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI
Front Oncol, 11, 668916
DOI 10.3389/fonc.2021.668916, PubMed 34094964 -
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
Int J Cancer, 149 (6), 1385-1397
DOI 10.1002/ijc.33672, PubMed 33961700 -
Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs"
Antimicrob Agents Chemother, 65 (6)
DOI 10.1128/AAC.00653-21, PubMed 34006613 -
The chemical defensome of five model teleost fish
Sci Rep, 11 (1), 10546
DOI 10.1038/s41598-021-89948-0, PubMed 34006915 -
The genetic structure of Norway
Eur J Hum Genet, 29 (11), 1710-1718
DOI 10.1038/s41431-021-00899-6, PubMed 34002043 -
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
Cancers (Basel), 13 (10)
DOI 10.3390/cancers13102370, PubMed 34069208 -
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
Autophagy, 17 (12), 4442-4452
DOI 10.1080/15548627.2021.1918915, PubMed 33978540 -
Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
Front Immunol, 12, 663865
DOI 10.3389/fimmu.2021.663865, PubMed 34046035 -
Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
BMC Biol, 19 (1), 85
DOI 10.1186/s12915-021-01012-5, PubMed 33966633 -
Improved adaptive radiotherapy to adjust for anatomical alterations during curative treatment for locally advanced lung cancer
Phys Imaging Radiat Oncol, 18, 51-54
DOI 10.1016/j.phro.2021.04.003, PubMed 34258408 -
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol, 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592 -
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost, 121 (12), 1588-1598
DOI 10.1055/a-1450-8568, PubMed 33742435 -
Chromothripsis as a pathogenic driver of multiple myeloma
Semin Cell Dev Biol, 123, 115-123
DOI 10.1016/j.semcdb.2021.04.014, PubMed 33958284 -
ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
Ann Surg Oncol, 28 (9), 5263-5264
DOI 10.1245/s10434-021-10036-8, PubMed 33939046 -
Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094815, PubMed 34062920 -
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
J Extracell Vesicles, 10 (7), e12093
DOI 10.1002/jev2.12093, PubMed 34035881 -
Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
EBioMedicine, 67, 103351
DOI 10.1016/j.ebiom.2021.103351, PubMed 33965875 -
Correction to: System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
Mol Diagn Ther, 25 (3), 387
DOI 10.1007/s40291-021-00527-5, PubMed 33950420 -
Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
Mol Oncol, 15 (8), 2026-2045
DOI 10.1002/1878-0261.12951, PubMed 33759347 -
Improved Formulation of 224Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP
Pharmaceutics, 13 (5)
DOI 10.3390/pharmaceutics13050634, PubMed 33946852 -
Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
Genome Med, 13 (1), 72
DOI 10.1186/s13073-021-00880-4, PubMed 33926515 -
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
Nanomaterials (Basel), 11 (5)
DOI 10.3390/nano11051140, PubMed 33924869 -
Metastases in locally advanced rectal cancer undergoing curatively intended treatment
Eur J Surg Oncol, 47 (9), 2377-2383
DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768 -
ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
Sci Rep, 11 (1), 9011
DOI 10.1038/s41598-021-87966-6, PubMed 33907223 -
Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
Cancers (Basel), 13 (9)
DOI 10.3390/cancers13092094, PubMed 33925994 -
True and Missed Interval Cancer in Organized Mammographic Screening: A Retrospective Review Study of Diagnostic and Prior Screening Mammograms
Acad Radiol, 29 Suppl 1, S180-S191
DOI 10.1016/j.acra.2021.03.022, PubMed 33926794 -
Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
J Mol Biol, 433 (13), 166987
DOI 10.1016/j.jmb.2021.166987, PubMed 33845085 -
Natural killer cell receptors regulate responses of HLA-E-restricted T cells
Sci Immunol, 6 (58)
DOI 10.1126/sciimmunol.abe9057, PubMed 33893172 -
The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
J Pers Med, 11 (5)
DOI 10.3390/jpm11050330, PubMed 33922147 -
Pharmacologic Control of CAR T Cells
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094320, PubMed 33919245 -
Expanding roles of cell cycle checkpoint inhibitors in radiation oncology
Int J Radiat Biol, 99 (6), 941-950
DOI 10.1080/09553002.2021.1913529, PubMed 33877959 -
New link between the RNA polymerase II-CTD and replication stress
Mol Cell Oncol, 8 (3), 1910008
DOI 10.1080/23723556.2021.1910008, PubMed 34027044 -
Cellular uptake of nanoparticles: Involvement of caveolae?
Precis Nanomed, 4 (2), 782-786
DOI 10.33218/001c.22201, PublikaID 365 -
Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
Int J Mol Sci, 22 (8)
DOI 10.3390/ijms22083887, PubMed 33918699 -
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
Br J Cancer, 125 (2), 240-246
DOI 10.1038/s41416-021-01377-y, PubMed 33837301 -
Recommendations for the FAIRification of genomic track metadata
F1000Res, 10
DOI 10.12688/f1000research.28449.1, PubMed 34249331 -
Correction to: Letter to the Editor-Recent advances in Lynch syndrome
Fam Cancer, 20 (2), 119
DOI 10.1007/s10689-021-00246-0, PubMed 33792829 -
Rapid nanopore-based DNA sequencing protocol of antibiotic-resistant bacteria for use in surveillance and outbreak investigation
Microb Genom, 7 (4)
DOI 10.1099/mgen.0.000557, PubMed 33885360 -
Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
Clin Exp Metastasis, 38 (2), 253
DOI 10.1007/s10585-021-10084-0, PubMed 33649933 -
Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
J Gastrointest Oncol, 12 (Suppl 1), S191-S203
DOI 10.21037/jgo-20-136, PubMed 33968437 -
Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks
Mol Oncol, 15 (5), 1277-1288
DOI 10.1002/1878-0261.12950, PubMed 33734563 -
Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis
Crit Rev Oncol Hematol, 161, 103312
DOI 10.1016/j.critrevonc.2021.103312, PubMed 33794308 -
mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
Commun Biol, 4 (1), 424
DOI 10.1038/s42003-021-01938-0, PubMed 33782531 -
COVID-19 in Cancer Patients, Risk Factors for Disease and Adverse Outcome, a Population-Based Study From Norway
Front Oncol, 11, 652535
DOI 10.3389/fonc.2021.652535, PubMed 33842366 -
Superior Graft-versus-Host Disease-Free Relapse-Free Survival in Matched Unrelated Donor Hematopoietic Stem Cell Transplantation with Anti-Thymocyte Globulin (ATG) Compared to Matched Related Donor without ATG
Transplant Cell Ther, 27 (7), 621.e1-621.e3
DOI 10.1016/j.jtct.2021.03.019, PubMed 33895156 -
Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
Sci Rep, 11 (1), 6731
DOI 10.1038/s41598-021-86239-6, PubMed 33762676 -
Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS
Blood Cancer Discov, 2 (3), 238-249
DOI 10.1158/2643-3230.BCD-20-0162, PubMed 34661156 -
Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
Pathology, 53 (6), 713-719
DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702 -
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576 -
Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
Biochem Biophys Res Commun, 552, 91-97
DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765 -
Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs
Antimicrob Agents Chemother, 65 (4)
DOI 10.1128/AAC.01146-20, PubMed 33468464 -
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Eur J Cancer, 148, 124-133
DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481 -
An extended APOBEC3A mutation signature in cancer
Nat Commun, 12 (1), 1602
DOI 10.1038/s41467-021-21891-0, PubMed 33707442 -
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
PLoS One, 16 (3), e0247615
DOI 10.1371/journal.pone.0247615, PubMed 33705460 -
Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
PLoS One, 16 (3), e0248140
DOI 10.1371/journal.pone.0248140, PubMed 33690666 -
ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
Ann Surg Oncol, 28 (11), 6846-6847
DOI 10.1245/s10434-021-09608-5, PubMed 33687615 -
Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use
PLoS One, 16 (3), e0248133
DOI 10.1371/journal.pone.0248133, PubMed 33662039 -
Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
Mol Pharmacol, 99 (5), 370-382
DOI 10.1124/molpharm.120.000170, PubMed 33674363 -
Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
Ann Surg Oncol, 28 (11), 6837-6845
DOI 10.1245/s10434-021-09605-8, PubMed 33651216 -
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904 -
A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
Hum Mutat, 42 (5), 551-566
DOI 10.1002/humu.24186, PubMed 33600059 -
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
Mol Syst Biol, 17 (3), e9526
DOI 10.15252/msb.20209526, PubMed 33750001 -
Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
Biomarkers, 26 (4), 302-308
DOI 10.1080/1354750X.2021.1891291, PubMed 33645339 -
Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
Sci Rep, 11 (1), 4613
DOI 10.1038/s41598-021-84268-9, PubMed 33633289 -
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy, 17 (4), 1046-1048
DOI 10.1080/15548627.2021.1887548, PubMed 33629888 -
Re-defining synthetic lethality by phenotypic profiling for precision oncology
Cell Chem Biol, 28 (3), 246-256
DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125 -
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483 -
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552 -
Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040927, PubMed 33672199 -
Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
DOI 10.1007/s00259-021-05243-0, PubMed 33606081 -
Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040779, PubMed 33668474 -
Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
Cancer Immunol Immunother, 70 (9), 2617-2624
DOI 10.1007/s00262-021-02876-w, PubMed 33580363 -
Artificial intelligence, machine learning, and drug repurposing in cancer
Expert Opin Drug Discov, 16 (9), 977-989
DOI 10.1080/17460441.2021.1883585, PubMed 33543671 -
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
J Cell Sci, 134 (3)
DOI 10.1242/jcs.250670, PubMed 33468622 -
miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
PLoS Comput Biol, 17 (2), e1008608
DOI 10.1371/journal.pcbi.1008608, PubMed 33566819 -
Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
Sci Rep, 11 (1), 3388
DOI 10.1038/s41598-021-81914-0, PubMed 33564016 -
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Nat Commun, 12 (1), 891
DOI 10.1038/s41467-020-20670-7, PubMed 33563959 -
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765 -
The Oslo Cyclotron Laboratory
Eur. Phys. J. Plus, 136 (2), 181
DOI 10.1140/epjp/s13360-021-01150-3 -
Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
Int J Environ Res Public Health, 18 (4)
DOI 10.3390/ijerph18041470, PubMed 33557277 -
Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
Stem Cell Rev Rep, 17 (1), 63-70
DOI 10.1007/s12015-020-10004-x, PubMed 32696426 -
Transport of nanoparticles across the endothelial cell layer
Nano Today, 36, 101029
DOI 10.1016/j.nantod.2020.101029 -
In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study
Breast Cancer Res, 23 (1), 17
DOI 10.1186/s13058-021-01393-z, PubMed 33526044 -
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
Sci Adv, 7 (8)
DOI 10.1126/sciadv.abe4038, PubMed 33608276 -
Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
Toxins (Basel), 13 (2)
DOI 10.3390/toxins13020102, PubMed 33573355 -
FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Commun Biol, 4 (1), 127
DOI 10.1038/s42003-021-01647-8, PubMed 33514811 -
Outcome of allogeneic hematopoietic stem cell transplantation for follicular lymphoma relapsing after autologous transplantation: analysis of the Japan Society for Hematopoietic Cell Transplantation
Bone Marrow Transplant, 56 (6), 1462-1466
DOI 10.1038/s41409-020-01192-8, PubMed 33514920 -
Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030499, PubMed 33525508 -
Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
JCO Precis Oncol, 5
DOI 10.1200/PO.20.00086, PubMed 34036235 -
MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
Mol Genet Metab Rep, 26, 100710
DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904 -
Editorial: Genomic Colocalization and Enrichment Analyses
Front Genet, 11, 617876
DOI 10.3389/fgene.2020.617876, PubMed 33574832 -
Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
Int J Pharm, 597, 120217
DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035 -
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
N Engl J Med, 384 (5), 428-439
DOI 10.1056/NEJMoa1913948, PubMed 33471991 -
Wetting regulates autophagy of phase-separated compartments and the cytosol
Nature, 591 (7848), 142-146
DOI 10.1038/s41586-020-2992-3, PubMed 33473217 -
Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
Blood Adv, 5 (1), 334-343
DOI 10.1182/bloodadvances.2020003423, PubMed 33570649 -
Efficient gene expression signature for a breast cancer immuno-subtype
PLoS One, 16 (1), e0245215
DOI 10.1371/journal.pone.0245215, PubMed 33434192 -
Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
Breast Cancer Res Treat, 187 (2), 515-523
DOI 10.1007/s10549-020-06072-9, PubMed 33423179 -
Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
Front Immunol, 11, 576756
DOI 10.3389/fimmu.2020.576756, PubMed 33488576 -
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154 -
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
Mol Oncol, 15 (2), 429-461
DOI 10.1002/1878-0261.12850, PubMed 33176066 -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751 -
System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
Mol Diagn Ther, 25 (1), 9-27
DOI 10.1007/s40291-020-00505-3, PubMed 33475988 -
Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
MAbs, 13 (1), 1893888
DOI 10.1080/19420862.2021.1893888, PubMed 33691596 -
RNA Interference: Story and Mechanisms
Methods Mol Biol, 2282, 1-15
DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566 -
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
Prog Chem Org Nat Prod, 115, 59-114
DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641 -
Calcium Carbonate Microparticles as Carriers of 224Ra: Impact of Specific Activity in Mice with Intraperitoneal Ovarian Cancer
Curr Radiopharm, 14 (2), 145-153
DOI 10.2174/1874471013666201201102056, PubMed 33261548
Publications 2020
-
Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison
Appl Radiat Isot, 170, 109572
DOI 10.1016/j.apradiso.2020.109572, PubMed 33461017 -
Multiobjective optimization identifies cancer-selective combination therapies
PLoS Comput Biol, 16 (12), e1008538
DOI 10.1371/journal.pcbi.1008538, PubMed 33370253 -
Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer - predictors of response and impact of previous radiotherapy
Acta Oncol, 60 (2), 149-156
DOI 10.1080/0284186X.2020.1854851, PubMed 33356733 -
Modeling molecular development of breast cancer in canine mammary tumors
Genome Res, 31 (2), 337-347
DOI 10.1101/gr.256388.119, PubMed 33361113 -
Use of Immunomodulating Drugs and Risk of Cutaneous Melanoma: A Nationwide Nested Case-Control Study
Clin Epidemiol, 12, 1389-1401
DOI 10.2147/CLEP.S269446, PubMed 33376408 -
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J Biol Chem, 296, 100179
DOI 10.1074/jbc.RA120.015285, PubMed 33303632 -
Anti-tumour immunity induces aberrant peptide presentation in melanoma
Nature, 590 (7845), 332-337
DOI 10.1038/s41586-020-03054-1, PubMed 33328638 -
Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
Int J Cancer, 148 (7), 1652-1657
DOI 10.1002/ijc.33425, PubMed 33284993 -
Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
Life Sci Alliance, 4 (2)
DOI 10.26508/lsa.202000965, PubMed 33318080 -
Prospects for NK Cell Therapy of Sarcoma
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123719, PubMed 33322371 -
Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
Aging (Albany NY), 12 (23), 23578-23597
DOI 10.18632/aging.202346, PubMed 33289702 -
The DLBCL90 gene-expression assay identifies double-hit lymphomas with high sensitivity in patients from two phase II clinical trials with high-risk diffuse large B-cell lymphoma
EJHaem, 2 (1), 104-108
DOI 10.1002/jha2.109, PubMed 35846101 -
Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
Front Oncol, 10, 523860
DOI 10.3389/fonc.2020.523860, PubMed 33344219 -
Combinatorial CAR design improves target restriction
J Biol Chem, 296, 100116
DOI 10.1074/jbc.RA120.016234, PubMed 33234592 -
A Systemic Protein Deviation Score Linked to PD-1+ CD8+ T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma
Med, 2 (2), 180-195.e5
DOI 10.1016/j.medj.2020.10.006, PubMed 35590201 -
Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects
Nat Commun, 11 (1), 6136
DOI 10.1038/s41467-020-19950-z, PubMed 33262326 -
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Genet Med, 23 (4), 705-712
DOI 10.1038/s41436-020-01029-1, PubMed 33257847 -
WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
Cell Rep, 33 (9), 108469
DOI 10.1016/j.celrep.2020.108469, PubMed 33264625 -
Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma
Cytotherapy, 23 (4), 329-338
DOI 10.1016/j.jcyt.2020.09.009, PubMed 33268029 -
Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
Front Oncol, 10, 590755
DOI 10.3389/fonc.2020.590755, PubMed 33324562 -
Systematic mapping of cancer cell target dependencies using high-throughput drug screening in triple-negative breast cancer
Comput Struct Biotechnol J, 18, 3819-3832
DOI 10.1016/j.csbj.2020.11.001, PubMed 33335681 -
Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
EMBO J, 39 (24), e104948
DOI 10.15252/embj.2020104948, PubMed 33226137 -
Accuracy and efficiency of germline variant calling pipelines for human genome data
Sci Rep, 10 (1), 20222
DOI 10.1038/s41598-020-77218-4, PubMed 33214604 -
Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
Ann Intern Med, 174 (2), 175-182
DOI 10.7326/M20-4011, PubMed 33197213 -
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Mol Ther, 29 (3), 1199-1213
DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301 -
Enhanced gene transfection of macrophages by photochemical internalization: Potential for gene-directed enzyme prodrug therapy of gliomas
Photodiagnosis Photodyn Ther, 33, 102098
DOI 10.1016/j.pdpdt.2020.102098, PubMed 33188941 -
Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB
Autophagy, 16 (12), 2305-2306
DOI 10.1080/15548627.2020.1837423, PubMed 33070669 -
Spatial transcriptomics inferred from pathology whole-slide images links tumor heterogeneity to survival in breast and lung cancer
Sci Rep, 10 (1), 18802
DOI 10.1038/s41598-020-75708-z, PubMed 33139755 -
Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
Proc Natl Acad Sci U S A, 117 (46), 28614-28624
DOI 10.1073/pnas.2014228117, PubMed 33139578 -
Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome
Hum Mutat, 41 (12), 2179-2194
DOI 10.1002/humu.24127, PubMed 33131181 -
Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
ESMO Open, 5 (6), e001040
DOI 10.1136/esmoopen-2020-001040, PubMed 33219056 -
Author Correction: STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (11), 1468-1469
DOI 10.1038/s41590-020-0803-5, PubMed 32929276 -
Photosensitizer delivery by fibrin glue: potential for bypassing the blood-brain barrier
Lasers Med Sci, 36 (5), 1031-1038
DOI 10.1007/s10103-020-03140-w, PubMed 33123852 -
Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency
Front Immunol, 11, 574738
DOI 10.3389/fimmu.2020.574738, PubMed 33193364 -
RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
Cancer Res, 81 (2), 315-331
DOI 10.1158/0008-5472.CAN-20-1871, PubMed 33067265 -
FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102992, PubMed 33076489 -
Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles
Front Immunol, 11, 561553
DOI 10.3389/fimmu.2020.561553, PubMed 33178188 -
Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer
Clin Lung Cancer, 22 (4), e555-e562
DOI 10.1016/j.cllc.2020.09.018, PubMed 33214079 -
Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
Eur Urol Open Sci, 21, 51-60
DOI 10.1016/j.euros.2020.08.007, PubMed 34337468 -
The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
F1000Res, 9
DOI 10.12688/f1000research.24887.1, PubMed 34367618 -
Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells
Sci Rep, 10 (1), 16992
DOI 10.1038/s41598-020-74083-z, PubMed 33046784 -
B cell signalling pathways-New targets for precision medicine in chronic lymphocytic leukaemia
Scand J Immunol, 92 (5), e12931
DOI 10.1111/sji.12931, PubMed 32640099 -
Microbial sensing by haematopoietic stem and progenitor cells: Vigilance against infections and immune education of myeloid cells
Scand J Immunol, 92 (5), e12957
DOI 10.1111/sji.12957, PubMed 32767789 -
AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer
iScience, 23 (11), 101649
DOI 10.1016/j.isci.2020.101649, PubMed 33103086 -
The Oncometabolite 5'-Deoxy-5'-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation
Front Immunol, 11, 2128
DOI 10.3389/fimmu.2020.02128, PubMed 33123121 -
Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk
Am J Hum Genet, 107 (5), 837-848
DOI 10.1016/j.ajhg.2020.09.001, PubMed 33022221 -
MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
Fam Cancer, 19 (4), 323-336
DOI 10.1007/s10689-020-00182-5, PubMed 32363481 -
Radiological review of prior screening mammograms of screen-detected breast cancer
Eur Radiol, 31 (4), 2568-2579
DOI 10.1007/s00330-020-07130-y, PubMed 33001307 -
Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
Nat Cell Biol, 22 (10), 1286
DOI 10.1038/s41556-020-0574-0, PubMed 32788721 -
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Oncoimmunology, 9 (1), 1824644
DOI 10.1080/2162402X.2020.1824644, PubMed 33457104 -
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
J Extracell Vesicles, 9 (1), 1816641
DOI 10.1080/20013078.2020.1816641, PubMed 33062218 -
Preventing a shock to the system. Two-pore channel 1 negatively regulates anaphylaxis
Cell Calcium, 92, 102289
DOI 10.1016/j.ceca.2020.102289, PubMed 33027744 -
Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
Br J Cancer, 123 (11), 1608-1615
DOI 10.1038/s41416-020-01056-4, PubMed 32939053 -
Future perspectives of surgical treatment of breast cancer
Ann Med Surg (Lond), 59, 93-95
DOI 10.1016/j.amsu.2020.09.021, PubMed 33005399 -
Drug-Loaded Lipid-Coated Hybrid Organic-Inorganic "Stealth" Nanoparticles for Cancer Therapy
Front Bioeng Biotechnol, 8, 1027
DOI 10.3389/fbioe.2020.01027, PubMed 33042960 -
Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase
J Chromatogr B Analyt Technol Biomed Life Sci, 1160, 122384
DOI 10.1016/j.jchromb.2020.122384, PubMed 32971370 -
miRNAs Predicted to Regulate Host Anti-viral Gene Pathways in IPNV-Challenged Atlantic Salmon Fry Are Affected by Viral Load, and Associated With the Major IPN Resistance QTL Genotypes in Late Infection
Front Immunol, 11, 2113
DOI 10.3389/fimmu.2020.02113, PubMed 33013890 -
Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients
Mol Oncol, 14 (11), 2759-2774
DOI 10.1002/1878-0261.12785, PubMed 33448640 -
Outcomes of COVID-19 in patients with CLL: a multicenter international experience
Blood, 136 (10), 1134-1143
DOI 10.1182/blood.2020006965, PubMed 32688395 -
Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med, 22 (9), 1569
DOI 10.1038/s41436-020-0892-4, PubMed 32690931 -
Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas
Endocr Relat Cancer, 27 (9), 457-468
DOI 10.1530/ERC-20-0064, PubMed 32580154 -
Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
Prostate Cancer, 2020, 7673684
DOI 10.1155/2020/7673684, PubMed 32908706 -
Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors
Allergy, 75 (11), 2829-2845
DOI 10.1111/all.14429, PubMed 32496587 -
Natural killer cell immunotypes related to COVID-19 disease severity
Sci Immunol, 5 (50)
DOI 10.1126/sciimmunol.abd6832, PubMed 32826343 -
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793 -
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling
Gastroenterology, 159 (6), 2146-2162.e33
DOI 10.1053/j.gastro.2020.08.018, PubMed 32805281 -
Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
EBioMedicine, 59, 102923
DOI 10.1016/j.ebiom.2020.102923, PubMed 32799124 -
Production of Recombinant Gelonin Using an Automated Liquid Chromatography System
Toxins (Basel), 12 (8)
DOI 10.3390/toxins12080519, PubMed 32823678 -
Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
J Mater Chem B, 8 (31), 6710-6738
DOI 10.1039/d0tb00861c, PubMed 32627783 -
Letter to the Editor-Recent advances in Lynch syndrome
Fam Cancer, 20 (2), 117-118
DOI 10.1007/s10689-020-00200-6, PubMed 32770425