Bente Brokstad Herlofson

  • Professor in oral surgery; PhD

Publications 2024

Huynh TM, Falk RS, Hellebust TP, Dale E, Astrup GL, Hjermstad MJ, Malinen E, Bjordal K, Kiserud CE, Herlofson BB, Nome R, Amdal CD (2024)
Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy
Radiother Oncol, 195, 110231
DOI 10.1016/j.radonc.2024.110231, PubMed 38518958

Monsen RE, Lerdal A, Nordgarden H, Gay CL, Herlofson BB (2024)
A comparison of the prevalence of dry mouth and other symptoms using two different versions of the Edmonton Symptom Assessment System on an inpatient palliative care unit
BMC Palliat Care, 23 (1), 75
DOI 10.1186/s12904-024-01405-7, PubMed 38493155

Taylor KJ, Amdal CD, Bjordal K, Astrup GL, Herlofson BB, Duprez F, Gama RR, Jacinto A, Hammerlid E, Scricciolo M, Jansen F, Verdonck-de Leeuw IM, Fanetti G, Guntinas-Lichius O, Inhestern J, Dragan T, Fabian A, Boehm A, Wöhner U, Kiyota N, Krüger M, Bonomo P, Pinto M, Nuyts S, Silva JC et al. (2024)
Long-term health-related quality of life in head and neck cancer survivors: A large multinational study
Int J Cancer, 154 (10), 1772-1785
DOI 10.1002/ijc.34861, PubMed 38312044

Publications 2023

Huynh TM, Dale E, Falk RS, Hellebust TP, Astrup GL, Malinen E, Edin NFJ, Bjordal K, Herlofson BB, Kiserud CE, Helland Å, Amdal CD (2023)
Radiation-induced long-term dysphagia in survivors of head and neck cancer and association with dose-volume parameters
Radiother Oncol, 190, 110044
DOI 10.1016/j.radonc.2023.110044, PubMed 38061420

Monsen RE, Kristoffersen AK, Gay CL, Herlofson BB, Fjeld KG, Hove LH, Nordgarden H, Tollisen A, Lerdal A, Enersen M (2023)
Identification and susceptibility testing of oral candidiasis in advanced cancer patients
BMC Oral Health, 23 (1), 223
DOI 10.1186/s12903-023-02950-y, PubMed 37072843

Taylor KJ, Amdal CD, Bjordal K, Astrup GL, Herlofson BB, Duprez F, Gama RR, Jacinto A, Hammerlid E, Scricciolo M, Jansen F, Verdonck-de Leeuw IM, Fanetti G, Guntinas-Lichius O, Inhestern J, Dragan T, Fabian A, Boehm A, Wöhner U, Kiyota N, Krüger M, Bonomo P, Pinto M, Nuyts S, Silva JC et al. (2023)
Serious Long-Term Effects of Head and Neck Cancer from the Survivors' Point of View
Healthcare (Basel), 11 (6)
DOI 10.3390/healthcare11060906, PubMed 36981562

Publications 2022

Huynh TTM, Aass HCD, Falk RS, Astrup GL, Helland Å, Bjøro T, Bjordal K, Dale E, Hellebust TP, Herlofson BB, Malinen E, Kiserud CE, Osnes T, Amdal CD (2022)
Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy
J Cancer Surviv, 17 (4), 1082-1093
DOI 10.1007/s11764-022-01273-1, PubMed 36350483

Hynne H, Aqrawi LA, Jensen JL, Thiede B, Palm Ø, Amdal CD, Westgaard KL, Herlofson BB, Utheim TP, Galtung HK (2022)
Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren's Syndrome Patients
Int J Mol Sci, 23 (7)
DOI 10.3390/ijms23073714, PubMed 35409074

Krüger TB, Syversen U, Herlofson BB, Lian AM, Reseland JE (2022)
Targeting a therapeutically relevant concentration of alendronate for in vitro studies on osteoblasts
Acta Odontol Scand, 80 (8), 619-625
DOI 10.1080/00016357.2022.2072522, PubMed 35605138

Tanem KE, Stensvold E, Wilberg P, Skaare AB, Brandal P, Herlofson BB (2022)
Oral and dental late effects in long-term survivors of childhood embryonal brain tumors
Support Care Cancer, 30 (12), 10233-10241
DOI 10.1007/s00520-022-07405-8, PubMed 36307656

Tanem KE, Stensvold E, Wilberg P, Skaare AB, Singh PB, Brandal P, Herlofson BB (2022)
Taste and smell function in long-term survivors after childhood medulloblastoma/CNS-PNET
Support Care Cancer, 30 (7), 6155-6162
DOI 10.1007/s00520-022-07048-9, PubMed 35426047

Tanem KE, Wilberg P, Diep PP, Ruud E, Skaare AB, Brinch L, Herlofson BB (2022)
Oral chronic GVHD after allogeneic stem cell transplantation without total body irradiation performed at a young age
Support Care Cancer, 30 (5), 4121-4128
DOI 10.1007/s00520-022-06836-7, PubMed 35075489

Publications 2021

Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP (2021)
Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
Sci Rep, 11 (1), 22419
DOI 10.1038/s41598-021-01844-9, PubMed 34789830

Ehrenstein V, Heide-Jørgensen U, Schiødt M, Akre O, Herlofson BB, Hansen S, Larsson Wexell C, Nørholt SE, Tretli S, Kjellman A, Glennane A, Lowe KA, Sørensen HT (2021)
Osteonecrosis of the jaw among patients with cancer treated with denosumab or zoledronic acid: Results of a regulator-mandated cohort postauthorization safety study in Denmark, Norway, and Sweden
Cancer, 127 (21), 4050-4058
DOI 10.1002/cncr.33802, PubMed 34310704

Krüger TB, Herlofson BB, Lian AM, Syversen U, Reseland JE (2021)
Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts
Bone Rep, 14, 100750
DOI 10.1016/j.bonr.2021.100750, PubMed 33553512

Monsen RE, Herlofson BB, Gay C, Fjeld KG, Hove LH, Malterud KE, Saghaug E, Slaaen J, Sundal T, Tollisen A, Lerdal A (2021)
A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial
Support Care Cancer, 29 (9), 4997-5007
DOI 10.1007/s00520-021-06021-2, PubMed 33586003

Singer S, Hammerlid E, Tomaszewska IM, Amdal CD, Bjordal K, Herlofson BB, Santos M, Silva JC, Mehanna H, Fullerton A, Brannan C, Gonzalez LF, Inhestern J, Pinto M, Arraras JI, Yarom N, Bonomo P, Baumann I, Galalae R, Nicolatou-Galitis O, Kiyota N, Raber-Durlacher J, Salem D, Fabian A, Boehm A et al. (2021)
Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale
Qual Life Res, 31 (3), 841-853
DOI 10.1007/s11136-021-02939-6, PubMed 34272632

Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL (2021)
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
DOI 10.1038/s41598-021-83635-w, PubMed 33597629

Publications 2020

Aqrawi LA, Chen X, Hynne H, Amdal C, Reppe S, Aass HCD, Rykke M, Hove LH, Young A, Herlofson BB, Westgaard KL, Utheim TP, Galtung HK, Jensen JL (2020)
Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
Cells, 9 (9)
DOI 10.3390/cells9092050, PubMed 32911805

Skaare AB, Hovden ES, Herlofson BB, Søland TM (2020)
Orofacial granulomatosis: a questionnaire study among Norwegian dental clinicians
Eur Arch Paediatr Dent, 21 (5), 557-564
DOI 10.1007/s40368-020-00511-3, PubMed 32020549

Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249

Publications 2019

Chen X, Aqrawi LA, Utheim TP, Tashbayev B, Utheim ØA, Reppe S, Hove LH, Herlofson BB, Singh PB, Palm Ø, Galtung HK, Jensen JCL (2019)
Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
Sci Rep, 9 (1), 7319
DOI 10.1038/s41598-019-43714-5, PubMed 31086200

Schiodt M, Otto S, Fedele S, Bedogni A, Nicolatou-Galitis O, Guggenberger R, Herlofson BB, Ristow O, Kofod T (2019)
Workshop of European task force on medication-related osteonecrosis of the jaw-Current challenges
Oral Dis, 25 (7), 1815-1821
DOI 10.1111/odi.13160, PubMed 31325201

Singh PB, Young A, Homayouni A, Hove LH, Petrovski BÉ, Herlofson BB, Palm Ø, Rykke M, Jensen JL (2019)
Distorted Taste and Impaired Oral Health in Patients with Sicca Complaints
Nutrients, 11 (2)
DOI 10.3390/nu11020264, PubMed 30682880

Publications 2018

Herlofson BB, Kjølle GK, Westgaard KL, Løndalen AM, Bruland ØS (2018)
Osteonecrosis of the Jaw in a Patient With Bone Metastatic Prostate Cancer After Long-term Bisphosphonate Treatment With Severe Deterioration Following Radium-223
Clin Genitourin Cancer, 16 (5), 328-331
DOI 10.1016/j.clgc.2018.05.003, PubMed 29861164

Publications 2017

Rusthen S, Young A, Herlofson BB, Aqrawi LA, Rykke M, Hove LH, Palm Ø, Jensen JL, Singh PB (2017)
Oral disorders, saliva secretion, and oral health-related quality of life in patients with primary Sjögren's syndrome
Eur J Oral Sci, 125 (4), 265-271
DOI 10.1111/eos.12358, PubMed 28643390

Tashbayev B, Rusthen S, Young A, Herlofson BB, Hove LH, Singh PB, Rykke M, Aqrawi LA, Chen X, Utheim ØA, Utheim TP, Palm Ø, Jensen JL (2017)
Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren's Syndrome
Sci Rep, 7 (1), 10761
DOI 10.1038/s41598-017-10809-w, PubMed 28883442

Publications 2016

Acquavella J, Ehrenstein V, Schiødt M, Heide-Jørgensen U, Kjellman A, Hansen S, Larsson Wexell C, Herlofson BB, Noerholt SE, Ma H, Öhrling K, Hernandez RK, Sørensen HT (2016)
Design and methods for a Scandinavian pharmacovigilance study of osteonecrosis of the jaw and serious infections among cancer patients treated with antiresorptive agents for the prevention of skeletal-related events
Clin Epidemiol, 8, 267-72
DOI 10.2147/CLEP.S107270, PubMed 27499646

Hjermstad MJ, Bergenmar M, Bjordal K, Fisher SE, Hofmeister D, Montel S, Nicolatou-Galitis O, Pinto M, Raber-Durlacher J, Singer S, Tomaszewska IM, Tomaszewski KA, Verdonck-de Leeuw I, Yarom N, Winstanley JB, Herlofson BB, EORTC QoL Group (2016)
International field testing of the psychometric properties of an EORTC quality of life module for oral health: the EORTC QLQ-OH15
Support Care Cancer, 24 (9), 3915-24
DOI 10.1007/s00520-016-3216-0, PubMed 27113466

Khullar SM, Katebi N, Herlofson BB, Tvedt D, Olsen BR (2016)
Evidence to support the hypothesis of tuberculosis as a cause of extreme osteonecrosis and osteomyelitis of the mandible in a West African population
Int J Oral Maxillofac Surg, 45 (12), 1600-1606
DOI 10.1016/j.ijom.2016.06.013, PubMed 27388429

Krüger TB, Herlofson BB, Landin MA, Reseland JE (2016)
Alendronate alters osteoblast activities
Acta Odontol Scand, 74 (7), 550-557
DOI 10.1080/00016357.2016.1217041, PubMed 27546224

Publications 2015

Otto S, Marx RE, Tröltzsch M, Ristow O, Ziebart T, Al-Nawas B, Groetz KA, Ehrenfeld M, Mercadante V, Porter S, Bedogni A, Campisi G, Fusco V, Dayisoylu E, Fliefel R, Herlofson BB, Pautke C, Kwon TG, Fedele S (2015)
Comments on "diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus"
J Bone Miner Res, 30 (6), 1113-5
DOI 10.1002/jbmr.2525, PubMed 25988662

Schiodt M, Larsson Wexell C, Herlofson BB, Giltvedt KM, Norholt SE, Ehrenstein V (2015)
Existing data sources for clinical epidemiology: Scandinavian Cohort for osteonecrosis of the jaw - work in progress and challenges
Clin Epidemiol, 7, 107-16
DOI 10.2147/CLEP.S71796, PubMed 25657594

Wilberg P, Kanellopoulos A, Ruud E, Hjermstad MJ, Fosså SD, Herlofson BB (2015)
Dental abnormalities after chemotherapy in long-term survivors of childhood acute lymphoblastic leukemia 7-40 years after diagnosis
Support Care Cancer, 24 (4), 1497-506
DOI 10.1007/s00520-015-2940-1, PubMed 26361760

Publications 2014

Eikesdal HP, Løes S, Herlofson BB (2014)
[Dental health when using bisphosphonates against breast cancer]
Tidsskr Nor Laegeforen, 134 (15), 1451
DOI 10.4045/tidsskr.14.0717, PubMed 25138400

Wilberg P, Hjermstad MJ, Ottesen S, Herlofson BB (2014)
Chemotherapy-associated oral sequelae in patients with cancers outside the head and neck region
J Pain Symptom Manage, 48 (6), 1060-9
DOI 10.1016/j.jpainsymman.2014.02.009, PubMed 24751438

Publications 2013

Krüger TB, Sharikabad MN, Herlofson BB (2013)
Bisphosphonate-related osteonecrosis of the jaw in four Nordic countries and an indication of under-reporting
Acta Odontol Scand, 71 (6), 1386-90
DOI 10.3109/00016357.2013.764007, PubMed 23351164

Migliorati CA, Saunders D, Conlon MS, Ingstad HK, Vaagen P, Palazzolo MJ, Herlofson BB (2013)
Assessing the association between bisphosphonate exposure and delayed mucosal healing after tooth extraction
J Am Dent Assoc, 144 (4), 406-14
DOI 10.14219/jada.archive.2013.0134, PubMed 23543695

Publications 2012

Hjermstad MJ, Bergenmar M, Fisher SE, Montel S, Nicolatou-Galitis O, Raber-Durlacher J, Singer S, Verdonck-de Leeuw I, Weis J, Yarom N, Herlofson BB (2012)
The EORTC QLQ-OH17: a supplementary module to the EORTC QLQ-C30 for assessment of oral health and quality of life in cancer patients
Eur J Cancer, 48 (14), 2203-11
DOI 10.1016/j.ejca.2012.04.003, PubMed 22572480

Khullar SM, Tvedt D, Chapman K, Herlofson BB (2012)
Sixty cases of extreme osteonecrosis and osteomyelitis of the mandible and maxilla in a West African population
Int J Oral Maxillofac Surg, 41 (8), 978-85
DOI 10.1016/j.ijom.2012.04.022, PubMed 22652445

Wilberg P, Hjermstad MJ, Ottesen S, Herlofson BB (2012)
Oral health is an important issue in end-of-life cancer care
Support Care Cancer, 20 (12), 3115-22
DOI 10.1007/s00520-012-1441-8, PubMed 22434497

Publications 2010

Wranicz P, Herlofson BB, Evensen JF, Kongsgaard UE (2010)
Prevention and treatment of trismus in head and neck cancer: A case report and a systematic review of the literature
Scand J Pain, 1 (2), 84-88
DOI 10.1016/j.sjpain.2010.01.006, PubMed 29913945

Publications 2006

Herlofson BB, Løken K (2006)
[How is the oral cavity affected by cancer treatment?]
Tidsskr Nor Laegeforen, 126 (10), 1349-52
PubMed 16691274

Steinsvoll S, Herlofson BB (2006)
[Oral manifestations in HIV infection]
Tidsskr Nor Laegeforen, 126 (9), 1218-21
PubMed 16670745

Publications 2005

Kolseth I, Herlofson BB, Pedersen A (2005)
Norwegian LongoVital and recurrent aphthous ulceration: a randomized, double-blind, placebo-controlled study
Oral Dis, 11 (6), 374-8
DOI 10.1111/j.1601-0825.2005.01133.x, PubMed 16269029

Publications 1997

Herlofson BB, Norman-Pedersen K, Redfors M, Fosså SD (1997)
Oral mucosal side effects of cytotoxic chemotherapy of testicular cancer. A retrospective study
Eur J Oral Sci, 105 (5 Pt 2), 523-6
DOI 10.1111/j.1600-0722.1997.tb00239.x, PubMed 9395118

Publications 1996

Herlofson BB, Barkvoll P (1996)
Oral mucosal desquamation caused by two toothpaste detergents in an experimental model
Eur J Oral Sci, 104 (1), 21-6
DOI 10.1111/j.1600-0722.1996.tb00041.x, PubMed 8653493

Herlofson BB, Barkvoll P (1996)
The effect of two toothpaste detergents on the frequency of recurrent aphthous ulcers
Acta Odontol Scand, 54 (3), 150-3
DOI 10.3109/00016359609003515, PubMed 8811135

Herlofson BB, Barkvoll P (1996)
Oral mucosal desquamation of pre- and post-menopausal women. A comparison of response to sodium lauryl sulphate in toothpastes
J Clin Periodontol, 23 (6), 567-71
DOI 10.1111/j.1600-051x.1996.tb01826.x, PubMed 8811477

Herlofson BB, Brodin P, Røed A (1996)
The effects of sodium lauryl sulfate on the phrenic nerve diaphragm preparation from the rat
Pharmacol Toxicol, 79 (5), 217-24
DOI 10.1111/j.1600-0773.1996.tb00263.x, PubMed 8936553

Herlofson BB, Brodin P, Aars H (1996)
Increased human gingival blood flow induced by sodium lauryl sulfate
J Clin Periodontol, 23 (11), 1004-7
DOI 10.1111/j.1600-051x.1996.tb00528.x, PubMed 8951628

Skaare AB, Herlofson BB, Barkvoll P (1996)
Mouthrinses containing triclosan reduce the incidence of recurrent aphthous ulcers (RAU)
J Clin Periodontol, 23 (8), 778-81
DOI 10.1111/j.1600-051x.1996.tb00609.x, PubMed 8877665

Publications 1994

Herlofson BB, Barkvoll P (1994)
Sodium lauryl sulfate and recurrent aphthous ulcers. A preliminary study
Acta Odontol Scand, 52 (5), 257-9
DOI 10.3109/00016359409029036, PubMed 7825393

Røed A, Herlofson BB (1994)
Inhibitory effects of HgCl2 on excitation-secretion coupling at the motor nerve terminal and excitation-contraction coupling in the muscle cell
Cell Mol Neurobiol, 14 (6), 623-36
DOI 10.1007/BF02088672, PubMed 7543823

Publications 1993

Herlofson BB, Barkvoll P (1993)
Desquamative effect of sodium lauryl sulfate on oral mucosa. A preliminary study
Acta Odontol Scand, 51 (1), 39-43
DOI 10.3109/00016359309041146, PubMed 8451922

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