Therapeutic drug monitoring of TNFinhibitors and other therapeutic antibodies.
Develop assays for novel immunotherapy drugs such as pembrolizumab, nivolumab and ipilimumab for monitoring drug levels in patients with lung cancer and malignant melanoma.
Develop assays for measuring rituximab and anti-rituximab for monitoring drug level and anti-drug antibody formation.
Detection of antibodies to transglutaminase in the HUNT4-cohort using an in-house dual label assay in collaborative study “Coeliac disease in HUNT”.
Screening for patient antibodies to HH1, a novel antibody-based drug used in lymphoma clinical trials (Lymrit).
Grimstad T, Carlsen A, Kvaløy JT, Bolstad N, Warren DJ, Aabakken L, Lundin KEA, Karlsen L, Steinsbø Ø, Omdal R(2025) Fatigue in Inflammatory Bowel Disease: No Effect of Serum Concentrations of Infliximab, Adalimumab or Anti-Drug Antibodies During Maintenance Therapy Scand J Immunol, 101(5), e70029 DOI 10.1111/sji.70029, PubMed 40289444
Rydland A, Heinicke F, Nyman TA, Trøseid AS, Flåm ST, Stensland M, Gehin J, Eikeland J, Øvstebø R, Mjaavatten MD, Lie BA(2025) Newly-diagnosed rheumatoid arthritis patients have elevated levels of plasma extracellular vesicles with protein cargo altered towards inflammatory processes Sci Rep, 15(1), 11632 DOI 10.1038/s41598-025-96325-8, PubMed 40185859
Cavalcanti LM, Thomas WM, Warren DJ, Mathews VJ(2025) Adaptive Feedforward Model Predictive Control for Torque Generation Through Asynchronous Intrafascicular Multi-Electrode Stimulation IEEE Trans Biomed Eng, 72(6), 2023-2034 DOI 10.1109/TBME.2025.3530924, PubMed 40031221
