Publications 2026

Kostas M, Munthe E, Haugsten EM, Mateus D, Sørensen V, Laerdahl JK, Szybowska P, Wiedlocha A, Lecaudey LA, Nakken S, Schink KO, Stenmark H, Wesche J (2026)
Unconventional activation of the proto-oncogene FGFR1 by extracellular phosphate via H₂O₂-mediated kinase oxidation
Cell Rep, 45 (6), 117504 (in press)
DOI 10.1016/j.celrep.2026.117504, PubMed 42247296

Publications 2022

Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
Br J Cancer, 127 (11), 1939-1953
DOI 10.1038/s41416-022-01973-6, PubMed 36097178

Publications 2021

Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
Cells, 10 (6)
DOI 10.3390/cells10061342, PubMed 34071546

Publications 2019

Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
Cells, 8 (6)
DOI 10.3390/cells8060518, PubMed 31146385

Publications 2018

Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290