Jens Henrik Norum
Position: Scientist, PhD
Phone: +47-22 78 14 83
Email:
 

Author network for Jens Henrik Norum by COREMINE medical


Publications 2017

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
Interrogating open issues in cancer precision medicine with patient-derived xenografts
Nat Rev Cancer, 17 (4), 254-268
PubMed 28104906

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
Interrogating open issues in cancer medicine with patient-derived xenografts
Nat Rev Cancer (in press)
PubMed 28912576

Publications 2015

Norum JH, Bergström Å, Andersson AB, Kuiper RV, Hoelzl MA, Sørlie T, Toftgård R (2015)
A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5
Dev Biol, 404 (2), 35-48
PubMed 26003047

Publications 2014

Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM (2014)
Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells
Cell Rep, 7 (3), 747-61
PubMed 24767994

Norum JH, Andersen K, Sørlie T (2014)
Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
Br J Surg, 101 (8), 925-38
PubMed 24849143

Publications 2013

Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM (2013)
GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
EMBO Mol Med, 5 (4), 488-508
PubMed 23436775

Publications 2008

Aesoy R, Sanchez BC, Norum JH, Lewensohn R, Viktorsson K, Linderholm B (2008)
An autocrine VEGF/VEGFR2 and p38 signaling loop confers resistance to 4-hydroxytamoxifen in MCF-7 breast cancer cells
Mol Cancer Res, 6 (10), 1630-8
PubMed 18922978

Publications 2006

Norum JH, Dawood H, Mattingly RR, Sandnes D, Levy FO (2006)
Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells
FEBS Lett, 581 (1), 15-20
PubMed 17174312

Publications 2005

Andressen KW, Norum JH, Levy FO, Krobert KA (2005)
Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT(7) receptor expression
Mol Pharmacol, 69 (1), 207-15
PubMed 16189297

Norum JH, Méthi T, Mattingly RR, Levy FO (2005)
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells
FEBS J, 272 (9), 2304-16
PubMed 15853814

Publications 2002

Norum JH, Hart K, Levy FO (2002)
Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a)
J Biol Chem, 278 (5), 3098-104
PubMed 12446729

Publications 2001

Ostvold AC, Norum JH, Mathiesen S, Wanvik B, Sefland I, Grundt K (2001)
Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo
Eur J Biochem, 268 (8), 2430-40
PubMed 11298763