Mouldy Sioud
Position: Group leader, DEA Pharm, Ph. D.
Phone: +47 22 78 14 14

Author network for Mouldy Sioud by COREMINE medical

Publications 2016

Mobergslien A, Peng Q, Vasovic V, Sioud M (2016)
Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth
Oncotarget, 7 (46), 75940-75953
PubMed 27713158

Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
Case Rep Med, 2016, 9639585
PubMed 27504122

Zins K, Schäfer R, Paulus P, Dobler S, Fakhari N, Sioud M, Aharinejad S, Abraham D (2016)
Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways
Oncotarget, 7 (29), 46187-46202
PubMed 27323822

Publications 2015

Iversen PO, Sioud M (2015)
Engineering therapeutic cancer vaccines that activate antitumor immunity
Methods Mol Biol, 1218, 263-8
PubMed 25319656

Mobergslien A, Sioud M (2015)
A facile method for interfering with off-target silencing mediated by the sense strand
Methods Mol Biol, 1218, 293-300
PubMed 25319659

Mobergslien A, Vasovic V, Mathiesen G, Fredriksen L, Westby P, Eijsink VG, Peng Q, Sioud M (2015)
Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells
Hum Vaccin Immunother, 11 (11), 2664-73
PubMed 26185907

Sioud M (2015)
Strategies for siRNA navigation to desired cells
Methods Mol Biol, 1218, 201-16
PubMed 25319653

Sioud M (2015)
Overcoming the challenges of siRNA activation of innate immunity: design better therapeutic siRNAs
Methods Mol Biol, 1218, 301-19
PubMed 25319660

Sioud M (2015)
RNA interference: mechanisms, technical challenges, and therapeutic opportunities
Methods Mol Biol, 1218, 1-15
PubMed 25319642

Sioud M (2015)
Modified 2'-ribose small RNAs function as Toll-like receptor-7/8 antagonists
Methods Mol Biol, 1218, 483-9
PubMed 25319669

Sioud M (2015)
Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation
Methods Mol Biol, 1218, 107-15
PubMed 25319647

Sioud M, Mobergslien A, Sæbøe-Larssen S (2015)
Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses
Methods Mol Biol, 1218, 269-76
PubMed 25319657

Sioud M, Westby P, Olsen JK, Mobergslien A (2015)
Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells
Mol Ther Methods Clin Dev, 2, 15043
PubMed 26605373

Zins K, Sioud M, Aharinejad S, Lucas T, Abraham D (2015)
Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy
Methods Mol Biol, 1218, 143-61
PubMed 25319650

Publications 2014

Sioud M (2014)
Engineering better immunotherapies via RNA interference
Hum Vaccin Immunother, 10 (11), 3165-74
PubMed 25483669

Publications 2013

Mobergslien A, Sioud M (2013)
Exosome-derived miRNAs and cellular miRNAs activate innate immunity
J Innate Immun, 6 (1), 105-10
PubMed 23774807

Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
Cancer Lett, 339 (1), 25-32
PubMed 23916608

Sioud M, Saebøe-Larssen S, Hetland TE, Kaern J, Mobergslien A, Kvalheim G (2013)
Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
Int J Oncol, 43 (1), 280-8
PubMed 23620105

Sioud M, Skorstad G, Mobergslien A, Sæbøe-Larssen S (2013)
A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells
FASEB J, 27 (8), 3272-83
PubMed 23671272

Zins K, Thomas A, Lucas T, Sioud M, Aharinejad S, Abraham D (2013)
Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts
Int J Mol Sci, 14 (9), 17958-71
PubMed 24005860

Publications 2012

Sioud M, Mobergslien A (2012)
Efficient siRNA targeted delivery into cancer cells by gastrin-releasing peptides
Bioconjug Chem, 23 (5), 1040-9
PubMed 22443209

Sioud M, Mobergslien A (2012)
Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide
Biochem Pharmacol, 84 (9), 1123-32
PubMed 22922046

Publications 2011

Mobergslien A, Sioud M (2011)
Galectin-1 and -3 gene silencing in immature and mature dendritic cells enhances T cell activation and interferon-γ production
J Leukoc Biol, 91 (3), 461-7
PubMed 22167721

Sioud M (2011)
Promises and challenges in developing RNAi as a research tool and therapy
Methods Mol Biol, 703, 173-87
PubMed 21125490

Sioud M (2011)
New insights into mesenchymal stromal cell-mediated T-cell suppression through galectins
Scand J Immunol, 73 (2), 79-84
PubMed 21198747

Publications 2010

Abraham D, Zins K, Sioud M, Lucas T, Schäfer R, Stanley ER, Aharinejad S (2010)
Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma
Int J Cancer, 126 (6), 1339-52
PubMed 19711348

Ben-Mahrez K, Sioud M (2010)
Presence of STRA-STRB linked streptomycin-resistance genes in clinical isolate of Escherichia coil 2418
Arch Inst Pasteur Tunis, 87 (1-2), 77-81
PubMed 21598829

Cekaite L, Clancy T, Sioud M (2010)
Increased miR-21 expression during human monocyte differentiation into DCs
Front Biosci (Elite Ed), 2, 818-28
PubMed 20515755

Fløisand Y, Sioud M (2010)
Recent advances in hematopoietic stem cell transplantation and perspectives of RNAi applications
Methods Mol Biol, 629, 507-23
PubMed 20387168

Fredriksen L, Mathiesen G, Sioud M, Eijsink VG (2010)
Cell wall anchoring of the 37-kilodalton oncofetal antigen by Lactobacillus plantarum for mucosal cancer vaccine delivery
Appl Environ Microbiol, 76 (21), 7359-62
PubMed 20851975

Iversen PO, Sørensen DR, Sioud M (2010)
A combined immunostimulatory and immunoinhibitory short interference RNA reduces hypercoagulability in a rat model of acute promyelocytic leukaemia
Thromb Haemost, 104 (2), 350-4
PubMed 20539915

Mobergslien A, Sioud M (2010)
Optimized protocols for siRNA delivery into monocytes and dendritic cells
Methods Mol Biol, 629, 71-85
PubMed 20387143

Sioud M (2010)
Development of TLR7/8 small RNA antagonists
Methods Mol Biol, 629, 387-94
PubMed 20387163

Sioud M (2010)
RNA therapeutics: function, design, and delivery. Preface
Methods Mol Biol, 629, v-vii
PubMed 20394129

Sioud M (2010)
Recent advances in small interfering RNA sensing by the immune system
N Biotechnol, 27 (3), 236-42
PubMed 20219711

Sioud M (2010)
Modulation of dendritic cell maturation and function by siRNA-bearing 5'-triphosphate
Methods Mol Biol, 629, 395-404
PubMed 20387164

Sioud M (2010)
What are the key targeted delivery technologies of siRNA now?
Methods Mol Biol, 629, 93-107
PubMed 20387145

Sioud M (2010)
Overcoming self-tolerance to tumour cells
Methods Mol Biol, 629, 495-505
PubMed 20387167

Sioud M (2010)
Advances in RNA sensing by the immune system: separation of siRNA unwanted effects from RNA interference
Methods Mol Biol, 629, 33-52
PubMed 20387141

Sioud M, Cekaite L (2010)
Profiling of miRNA expression and prediction of target genes
Methods Mol Biol, 629, 257-71
PubMed 20387154

Sioud M, Mobergslien A, Boudabous A, Fløisand Y (2010)
Evidence for the involvement of galectin-3 in mesenchymal stem cell suppression of allogeneic T-cell proliferation
Scand J Immunol, 71 (4), 267-74
PubMed 20384870

Sioud M, Mobergslien A, Boudabous A, Fløisand Y (2010)
Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
Int J Oncol, 38 (2), 385-90
PubMed 21165555

Sørensen DR, Sioud M (2010)
Systemic delivery of synthetic siRNAs
Methods Mol Biol, 629, 87-91
PubMed 20387144

Publications 2009

Aharinejad S, Sioud M, Lucas T, Abraham D (2009)
Targeting stromal-cancer cell interactions with siRNAs
Methods Mol Biol, 487, 243-66
PubMed 19301651

Cekaite L, Hovig E, Sioud M (2009)
Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
Methods Mol Biol, 524, 273-85
PubMed 19377952

Flatekval GF, Sioud M (2009)
Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase
Immunology, 128 (1 Suppl), e837-48
PubMed 19740345

Hauge H, Fjelland KE, Sioud M, Aasheim HC (2009)
Evidence for the involvement of FAM110C protein in cell spreading and migration
Cell Signal, 21 (12), 1866-73
PubMed 19698782

Iversen PO, Semaeva E, Sorensen DR, Wiig H, Sioud M (2009)
Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells
Transl Oncol, 2 (4), 242-6
PubMed 19956385

Sioud M (2009)
Deciphering the code of innate immunity recognition of siRNAs
Methods Mol Biol, 487, 41-59
PubMed 19301641

Sioud M (2009)
Targeted delivery of antisense oligonucleotides and siRNAs into mammalian cells
Methods Mol Biol, 487, 61-82
PubMed 19301642

Sioud M (2009)
Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines?
Scand J Immunol, 70 (6), 516-25
PubMed 19906192

Sioud M, Boudabous A, Cekaite L (2009)
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
Int J Mol Med, 23 (1), 33-9
PubMed 19082504

Sioud M, Fløisand Y (2009)
NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation
J Leukoc Biol, 85 (6), 939-46
PubMed 19244164

Publications 2008

Abraham D, Zins K, Sioud M, Lucas T, Aharinejad S (2008)
Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts
Front Biosci, 13, 5571-9
PubMed 18508606

Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PØ, Sandal T, Lønning PE, Flatmark T, Enger PØ, Bjerkvig R, Sioud M, Stallcup WB (2008)
The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
Oncogene, 27 (39), 5182-94
PubMed 18469852

Shadidi M, Sørensen D, Dybwad A, Furset G, Sioud M (2008)
Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma
Int J Oncol, 32 (1), 241-7
PubMed 18097564

Sioud M (2008)
Does the understanding of immune activation by RNA predict the design of safe siRNAs?
Front Biosci, 13, 4379-92
PubMed 18508517

Sioud M, Cekaite L (2008)
Expression profiling of microRNAs in cancer cells: technical considerations
Methods Mol Biol, 439, 179-90
PubMed 18370103

Walchli S, Sioud M (2008)
Vector-based delivery of siRNAs: in vitro and in vivo challenges
Front Biosci, 13, 3488-93
PubMed 18508450

Publications 2007

Aharinejad S, Sioud M, Lucas T, Abraham D (2007)
Target validation using RNA interference in solid tumors
Methods Mol Biol, 361, 227-38
PubMed 17172715

Cekaite L, Hovig E, Sioud M (2007)
Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
Methods Mol Biol, 360, 335-48
PubMed 17172738

Furset G, Fløisand Y, Sioud M (2007)
Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
Immunology, 123 (2), 263-71
PubMed 17725606

Røsok Ø, Sioud M (2007)
Discovery of differentially expressed genes: technical considerations
Methods Mol Biol, 360, 115-29
PubMed 17172727

Sioud M (2007)
An overview of the immune system and technical advances in tumor antigen discovery and validation
Methods Mol Biol, 360, 277-318
PubMed 17172735

Sioud M (2007)
RNA interference and innate immunity
Adv Drug Deliv Rev, 59 (2-3), 153-63
PubMed 17459518

Sioud M (2007)
Main approaches to target discovery and validation
Methods Mol Biol, 360, 1-12
PubMed 17172722

Sioud M, Fløisand Y (2007)
TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response
Eur J Immunol, 37 (10), 2834-46
PubMed 17853407

Sioud M, Furset G, Cekaite L (2007)
Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
Biochem Biophys Res Commun, 361 (1), 122-6
PubMed 17658482

Sioud M, Leirdal M (2007)
Druggable signaling proteins
Methods Mol Biol, 361, 1-24
PubMed 17172705

Sioud M, Melien O (2007)
Treatment options and individualized medicine
Methods Mol Biol, 361, 327-40
PubMed 17172721

Zins K, Abraham D, Sioud M, Aharinejad S (2007)
Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway
Cancer Res, 67 (3), 1038-45
PubMed 17283136

Publications 2006

Angell-Petersen E, Spetalen S, Madsen SJ, Sun CH, Peng Q, Carper SW, Sioud M, Hirschberg H (2006)
Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
J Neurosurg, 104 (1), 109-17
PubMed 16509154

Cekaite L, Furset G, Hovig E, Sioud M (2006)
Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
J Mol Biol, 365 (1), 90-108
PubMed 17054988

Furset G, Sioud M (2006)
Design of bifunctional siRNAs: combining immunostimulation and gene-silencing in one single siRNA molecule
Biochem Biophys Res Commun, 352 (3), 642-9
PubMed 17150189

Huynh T, Wälchli S, Sioud M (2006)
Transcriptional targeting of small interfering RNAs into cancer cells
Biochem Biophys Res Commun, 350 (4), 854-9
PubMed 17034763

Sioud M (2006)
RNA interference below the immune radar
Nat Biotechnol, 24 (5), 521-2
PubMed 16680132

Sioud M (2006)
Innate sensing of self and non-self RNAs by Toll-like receptors
Trends Mol Med, 12 (4), 167-76
PubMed 16530484

Sioud M (2006)
Ribozymes and siRnas: from structure to preclinical applications
Handb Exp Pharmacol (173), 223-42
PubMed 16594618

Sioud M (2006)
RNAi therapy: antibodies guide the way
Gene Ther, 13 (3), 194-5
PubMed 17243203

Sioud M (2006)
Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses
Eur J Immunol, 36 (5), 1222-30
PubMed 16609928

Sioud M, Fløisand Y, Forfang L, Lund-Johansen F (2006)
Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage
J Mol Biol, 364 (5), 945-54
PubMed 17049554

Sioud M, Furset G (2006)
Molecular basis for the immunostimulatory potency of small interfering RNAs
J Biomed Biotechnol, 2006 (4), 23429
PubMed 17057361

Sioud M, Haoudi A (2006)
RNA interference
J Biomed Biotechnol, 2006 (4), 89018
PubMed 17057373

Publications 2005

Patzke S, Hauge H, Sioud M, Finne EF, Sivertsen EA, Delabie J, Stokke T, Aasheim HC (2005)
Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
Oncogene, 24 (7), 1159-73
PubMed 15580290

Røsok O, Sioud M (2005)
Systematic search for natural antisense transcripts in eukaryotes (review)
Int J Mol Med, 15 (2), 197-203
PubMed 15647831

Sioud M (2005)
siRNA delivery in vivo
Methods Mol Biol, 309, 237-49
PubMed 15990404

Sioud M (2005)
Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
J Mol Biol, 348 (5), 1079-90
PubMed 15854645

Sioud M (2005)
On the delivery of small interfering RNAs into mammalian cells
Expert Opin Drug Deliv, 2 (4), 639-51
PubMed 16296791

Sioud M, Iversen PO (2005)
Ribozymes, DNAzymes and small interfering RNAs as therapeutics
Curr Drug Targets, 6 (6), 647-53
PubMed 16178798

Sioud M, Røsok Ø (2005)
High-throughput analysis of microRNA gene expression using sensitive probes
Methods Mol Biol, 309, 311-20
PubMed 15990410

Sioud M, Wälchli S (2005)
Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
Methods Mol Biol, 309, 83-91
PubMed 15990399

Publications 2004

Aharinejad S, Paulus P, Sioud M, Hofmann M, Zins K, Schäfer R, Stanley ER, Abraham D (2004)
Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
Cancer Res, 64 (15), 5378-84
PubMed 15289345

Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
Proteomics, 4 (9), 2572-82
PubMed 15352232

Hirschberg H, Madsen S, Angell-Petersen E, Peng Q, Sioud M, Sun CH, Sorensen DR (2004)
Repetitive 5-aminolevulinic acid mediated photodynamic therapy of rat glioma
P SOC PHOTO-OPT INS, 5312, 405-414

Iversen PO, Sioud M (2004)
Inhibition of gene expression by nucleic acid enzymes in rodent models of human disease
Methods Mol Biol, 252, 451-6
PubMed 15017070

Leirdal M, Shadidy M, Røsok Ø, Sioud M (2004)
Identification of genes differentially expressed in breast cancer cell line SKBR3: potential identification of new prognostic biomarkers
Int J Mol Med, 14 (2), 217-22
PubMed 15254768

Leirdal M, Sioud M (2004)
Gene-array analysis of glioma cells after treatment with an anti-PKCalpha siRNA: a general protocol
Methods Mol Biol, 252, 493-500
PubMed 15017074

Røsok O, Sioud M (2004)
An experimental approach for systematic identification of antisense transcripts
Discov Med, 4 (20), 58-60
PubMed 20705023

Shadidi M, Sioud M (2004)
Selection of peptides for specific delivery of oligonucleotides into cancer cells
Methods Mol Biol, 252, 569-80
PubMed 15017081

Sioud M (2004)
Therapeutic siRNAs
Trends Pharmacol Sci, 25 (1), 22-8
PubMed 14723975

Sioud M (2004)
Ribozyme- and siRNA-mediated mRNA degradation: a general introduction
Methods Mol Biol, 252, 1-8
PubMed 15017038

Sioud M (2004)
Therapeutic potential of small interfering RNAs
Drug Future, 29 (7), 741-750

Sioud M, Leirdal M (2004)
Potential design rules and enzymatic synthesis of siRNAs
Methods Mol Biol, 252, 457-69
PubMed 15017071

Sioud M, Røsok O (2004)
Profiling microRNA expression using sensitive cDNA probes and filter arrays
Biotechniques, 37 (4), 574-6, 578-80
PubMed 15517969

Sioud M, Sørensen DR (2004)
Systemic delivery of synthetic siRNAs
Methods Mol Biol, 252, 515-22
PubMed 15017077

Publications 2003

Dybwad A, Lambin P, Sioud M, Zouali M (2003)
Probing the specificity of human myeloma proteins with a random peptide phage library
Scand J Immunol, 57 (6), 583-90
PubMed 12791097

Røsok Ø, Sioud M (2003)
Systematic identification of sense-antisense transcripts in mammalian cells
Nat Biotechnol, 22 (1), 104-8
PubMed 14704709

Shadidi M, Sioud M (2003)
Selective targeting of cancer cells using synthetic peptides
Drug Resist Updat, 6 (6), 363-71
PubMed 14744500

Sioud M, Sørensen D (2003)
Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens
Eur J Immunol, 33 (1), 38-45
PubMed 12594830

Sioud M, Sørensen DR (2003)
Cationic liposome-mediated delivery of siRNAs in adult mice
Biochem Biophys Res Commun, 312 (4), 1220-5
PubMed 14652004

Sørensen DR, Leirdal M, Sioud M (2003)
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
J Mol Biol, 327 (4), 761-6
PubMed 12654261

Publications 2002

Iversen PO, Emanuel PD, Sioud M (2002)
Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
Blood, 99 (11), 4147-53
PubMed 12010819

Leirdal M, Sioud M (2002)
[Tyrosine kinase receptor-ras-ERK signal transduction pathway as therapeutic tarfet in cancer]
Tidsskr Nor Laegeforen, 122 (2), 178-82
PubMed 11873574

Leirdal M, Sioud M (2002)
Gene silencing in mammalian cells by preformed small RNA duplexes
Biochem. Biophys. Res. Commun., 295 (3), PII S0006-291X(02)00736-2-748

Leirdal M, Sioud M (2002)
Gene silencing in mammalian cells by preformed small RNA duplexes
Biochem Biophys Res Commun, 295 (3), 744-8
PubMed 12099702

Shadidi M, Sioud M (2002)
Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells
FASEB J, 17 (2), 256-8
PubMed 12490548

Sioud M (2002)
How does autoimmunity cause tumor regression? A potential mechanism involving cross-reaction through epitope mimicry
Mol Med, 8 (3), 115-9
PubMed 12142543

Sorensen DR, Leirdal M, Iversen PO, Sioud M (2002)
Combination of endostatin and a protein kinase Calpha DNA enzyme improves the survival of rats with malignant glioma
Neoplasia, 4 (6), 474-9
PubMed 12407440

Publications 2001

Hansen MH, Ostenstad B, Sioud M (2001)
Antigen-specific IgG antibodies in stage IV long-time survival breast cancer patients
Mol Med, 7 (4), 230-9
PubMed 11471567

Hansen MH, Ostenstad B, Sioud M (2001)
Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour
Int J Oncol, 19 (6), 1303-9
PubMed 11713604

Iversen PO, Nicolaysen G, Sioud M (2001)
DNA enzyme targeting TNF-alpha mRNA improves hemodynamic performance in rats with postinfarction heart failure
Am J Physiol Heart Circ Physiol, 281 (5), H2211-7
PubMed 11668085

Melien O, Christoffersen T, Sioud M (2001)
Evidence for the involvement of G(i2) in activation of extracellular signal-regulated kinases in hepatocytes
BMC Cell Biol., 2, art. no.-13

Melien O, Christoffersen T, Sioud M (2001)
Evidence for the involvement of Gi2 in activation of extracellular signal-regulated kinases in hepatocytes
BMC Cell Biol, 2, 13
PubMed 11495629

Shadidi M, Sioud M (2001)
An anti-leukemic single chain Fv antibody selected from a synthetic human phage antibody library
Biochem Biophys Res Commun, 280 (2), 548-52
PubMed 11162553

Sioud M (2001)
Nucleic acid enzymes as a novel generation of anti-gene agents
Curr Mol Med, 1 (5), 575-88
PubMed 11899232

Sioud M, Hansen MH (2001)
Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries
Eur J Immunol, 31 (3), 716-25
PubMed 11241275

Publications 2000

Hansen MH, Dybwad A, Førre O, Sioud M (2000)
Probing antinuclear antibody specificities by peptide phage display libraries
Clin Exp Rheumatol, 18 (4), 465-72
PubMed 10949721

Josefsen D, Myklebust JH, Lømo J, Sioud M, Blomhoff HK, Smeland EB (2000)
Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
Stem Cells, 18 (4), 261-72
PubMed 10924092

Leirdal M, Sioud M (2000)
Protein kinase Calpha isoform regulates the activation of the MAP kinase ERK1/2 in human glioma cells: involvement in cell survival and gene expression
Mol Cell Biol Res Commun, 4 (2), 106-10
PubMed 11170840

Myklebust JH, Smeland EB, Josefsen D, Sioud M (2000)
Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
Blood, 95 (2), 510-8
PubMed 10627456

Sioud M, Hansen M, Dybwad A (2000)
Profiling the immune responses in patient sera with peptide and cDNA display libraries
Int J Mol Med, 6 (2), 123-8
PubMed 10891554

Sioud M, Leirdal M (2000)
Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application
J Mol Biol, 296 (3), 937-47
PubMed 10677293

Sioud M, Leirdal M (2000)
Therapeutic RNA and DNA enzymes
Biochem Pharmacol, 60 (8), 1023-6
PubMed 11007937

Publications 1999

Leirdal M, Sioud M (1999)
Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells
Br J Cancer, 80 (10), 1558-64
PubMed 10408397

Sioud M (1999)
Application of preformed hammerhead ribozymes in the gene therapy of cancer (review)
Int J Mol Med, 3 (4), 381-4
PubMed 10085409

Sioud M, Leirdal M (1999)
Substitution of the 2'-hydroxyl group at position 2.1 by an amino group interferes with Mg(2+) binding and efficient cleavage by hammerhead ribozyme
Biochem Biophys Res Commun, 262 (2), 461-6
PubMed 10462497

Publications 1998

Iversen PO, Sioud M (1998)
Modulation of granulocyte-macrophage colony-stimulating factor gene expression by a tumor necrosis factor specific ribozyme in juvenile myelomonocytic leukemic cells
Blood, 92 (11), 4263-8
PubMed 9834232

Leirdal M, Sioud M (1998)
High cleavage activity and stability of hammerhead ribozymes with a uniform 2'-amino pyrimidine modification
Biochem Biophys Res Commun, 250 (1), 171-4
PubMed 9735351

Sioud M, Mellbye O, Førre O (1998)
Analysis of the NF-kappa B p65 subunit, Fas antigen, Fas ligand and Bcl-2-related proteins in the synovium of RA and polyarticular JRA
Clin Exp Rheumatol, 16 (2), 125-34
PubMed 9536387

Sioud M, Sørensen DR (1998)
A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth
Nat Biotechnol, 16 (6), 556-61
PubMed 9624687

Publications 1997

Dybwad A, Fłrre O, Sioud M (1997)
Probing for cerebrospinal fluid antibody specificities by a panel of random peptide libraries
Autoimmunity, 25 (2), 85-9
PubMed 9189009

Sioud M (1997)
Effects of variations in length of hammerhead ribozyme antisense arms upon the cleavage of longer RNA substrates
Nucleic Acids Res, 25 (2), 333-8
PubMed 9016562

Sioud M, Opstad A, Hendry P, Lockett TJ, Jennings PA, McCall MJ (1997)
A minimised hammerhead ribozyme with activity against interleukin-2 in human cells
Biochem Biophys Res Commun, 231 (2), 397-402
PubMed 9070287

Publications 1996

Dybwad A, Førre O, Sioud M (1996)
Increased serum and synovial fluid antibodies to immunoselected peptides in patients with rheumatoid arthritis
Ann Rheum Dis, 55 (7), 437-41
PubMed 8774161

Fakhfakh F, Ayadi H, Bahloul Z, Jarraya A, Sioud M, Zouali M (1996)
Antibody epitopes probed by immunoselected phage-display library peptides in members of a family with various rheumatic manifestations
Clin Exp Rheumatol, 14 (6), 607-11
PubMed 8978954

Sioud M (1996)
Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by peritoneal cells in vitro and in vivo
Eur J Immunol, 26 (5), 1026-31
PubMed 8647163

Sioud M, Førre O, Dybwad A (1996)
Selection of ligands for polyclonal antibodies from random peptide libraries: potential identification of (auto)antigens that may trigger B and T cell responses in autoimmune diseases
Clin Immunol Immunopathol, 79 (2), 105-14
PubMed 8620616

Sioud M, Jespersen L (1996)
Enhancement of hammerhead ribozyme catalysis by glyceraldehyde-3-phosphate dehydrogenase
J Mol Biol, 257 (4), 775-89
PubMed 8636981

Tougourti MN, Sioud M, Hassen Z, Bouhali R, Hamza M (1996)
[Psychiatric disorders and endocrine diseases. Apropos of a 8 cases]
Tunis Med, 74 (12), 549-52
PubMed 9506057

Publications 1995

Dybwad A, Bogen B, Natvig JB, Førre O, Sioud M (1995)
Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
Clin Exp Immunol, 102 (2), 438-42
PubMed 7586703

Dybwad A, Førre O, Natvig JB, Sioud M (1995)
Structural characterization of peptides that bind synovial fluid antibodies from RA patients: a novel strategy for identification of disease-related epitopes using a random peptide library
Clin Immunol Immunopathol, 75 (1), 45-50
PubMed 7533685

Kjeldsen-Kragh J, Mellbye OJ, Haugen M, Mollnes TE, Hammer HB, Sioud M, Førre O (1995)
Changes in laboratory variables in rheumatoid arthritis patients during a trial of fasting and one-year vegetarian diet
Scand J Rheumatol, 24 (2), 85-93
PubMed 7747149

Kjeldsen-Kragh J, Rashid T, Dybwad A, Sioud M, Haugen M, Førre O, Ebringer A (1995)
Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with fasting and a one year vegetarian diet
Ann Rheum Dis, 54 (3), 221-4
PubMed 7748020

Ostenstad B, Dybwad A, Lea T, Førre O, Vinje O, Sioud M (1995)
Evidence for monoclonal expansion of synovial T cells bearing V alpha 2.1/V beta 5.5 gene segments and recognizing a synthetic peptide that shares homology with a number of putative autoantigens
Immunology, 86 (2), 168-75
PubMed 7490114

Ostenstad B, Sioud M, Schlichting E, Lea T, Harboe M (1995)
Freshly isolated tumour-infiltrating T-lymphocytes have a high cytotoxic potential, as measured by their ability to induce apoptosis in the target cell
Scand J Immunol, 41 (1), 42-8
PubMed 7824887

Tougourti MN, Sioud M, Hamza M (1995)
[Cerebrovascular accidents in Horton's disease. Apropos of a case]
Tunis Med, 73 (5), 195-9
PubMed 9507283

Tougourti MN, Sioud M, Kheder L, Hamza M, Miled M (1995)
[Antiphospholipid syndrome]
Tunis Med, 73 (2), 95-103
PubMed 9506150

Publications 1994

Ostenstad B, Sioud M, Lea T, Schlichting E, Harboe M (1994)
Limited heterogeneity in the T-cell receptor V-gene usage in lymphocytes infiltrating human colorectal tumours
Br J Cancer, 69 (6), 1078-82
PubMed 8198973

Sioud M (1994)
Interaction between tumour necrosis factor alpha ribozyme and cellular proteins. Involvement in ribozyme stability and activity
J Mol Biol, 242 (5), 619-29
PubMed 7932719

Sioud M, Dybwad A, Jespersen L, Suleyman S, Natvig JB, Førre O (1994)
Characterization of naturally occurring autoantibodies against tumour necrosis factor-alpha (TNF-alpha): in vitro function and precise epitope mapping by phage epitope library
Clin Exp Immunol, 98 (3), 520-5
PubMed 7994916

Sioud M, Opstad A, Zhao JQ, Levitz R, Benham C, Drlica K (1994)
In vivo decay kinetic parameters of hammerhead ribozymes
Nucleic Acids Res, 22 (25), 5571-5
PubMed 7838709

Scand. J. Immunol., 40 (6), 681-690

Suleyman S, Thompson KM, Førre O, Sioud M, Randen I, Mageed RA, Natvig JB (1994)
Three new cross-reacting idiotopes as markers for the products of two distinct human VH3 genes expressed in the early repertoire
Scand J Immunol, 40 (6), 681-90
PubMed 7527936

Tougourti MN, Sioud M, Khedher I, Houman H, Hamza M, Miled M (1994)
[Iatrogenic accidents in the hospital environment]
Tunis Med, 72 (11), 625-30
PubMed 7762090

Publications 1993

Dybwad A, Førre O, Kjeldsen-Kragh J, Natvig JB, Sioud M (1993)
Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library
Eur J Immunol, 23 (12), 3189-93
PubMed 7504991

Førre O, Sioud M (1993)
T cell receptor variable region gene usage in juvenile chronic arthritis
Clin Exp Rheumatol, 11 Suppl 9, S43-6
PubMed 8354007

Kjeldsen-Kragh J, Quayle AJ, Skålhegg BS, Sioud M, Førre O (1993)
Selective activation of resting human gamma delta T lymphocytes by interleukin-2
Eur J Immunol, 23 (9), 2092-9
PubMed 8370391

Suleyman S, Hosono O, Sioud M, Randen I, Thompson KM, Førre O, Natvig JB (1993)
Differentiation of human lambda I variable regions with a monoclonal antibody to a defined, germ-line-encoded idiotope correlates with V lambda Ia chemical structure
J Immunol, 150 (12), 5466-75
PubMed 8515071

Publications 1992

Quayle AJ, Wilson KB, Li SG, Kjeldsen-Kragh J, Oftung F, Shinnick T, Sioud M, Førre O, Capra JD, Natvig JB (1992)
Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid
Eur J Immunol, 22 (5), 1315-22
PubMed 1577070

Sioud M, Kjeldsen-Kragh J, Suleyman S, Vinje O, Natvig JB, Førre O (1992)
Limited heterogeneity of T cell receptor variable region gene usage in juvenile rheumatoid arthritis synovial T cells
Eur J Immunol, 22 (9), 2413-8
PubMed 1387614

Sioud M, Natvig JB, Førre O (1992)
Preformed ribozyme destroys tumour necrosis factor mRNA in human cells
J Mol Biol, 223 (4), 831-5
PubMed 1538398

Waalen K, Sioud M, Natvig JB, Førre O (1992)
Spontaneous in vivo gene transcription of interleukin-2, interleukin-3, interleukin-4, interleukin-6, interferon-gamma, interleukin-2 receptor (CD25) and proto-oncogene c-myc by rheumatoid synovial T lymphocytes
Scand J Immunol, 36 (6), 865-73
PubMed 1462123

Publications 1991

Sioud M, Drlica K (1991)
Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme
Proc Natl Acad Sci U S A, 88 (16), 7303-7
PubMed 1871136

Sioud M, Førre O, Natvig JB (1991)
T cell receptor delta diversity of freshly isolated T lymphocytes in rheumatoid synovitis
Eur J Immunol, 21 (1), 239-41
PubMed 1825059

Sioud M, Kjeldsen-Kragh J, Quayle AJ, Wiker HG, Sørskaar D, Natvig JB, Førre O (1991)
Immune responses to 18.6 and 30-kDa mycobacterial antigens in rheumatoid patients, and V beta usage by specific synovial T-cell lines and fresh T cells
Scand J Immunol, 34 (6), 803-12
PubMed 1836278

Publications 1990

Pascual V, Randen I, Thompson K, Sioud M, Forre O, Natvig J, Capra JD (1990)
The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes
J Clin Invest, 86 (4), 1320-8
PubMed 2170450

Sioud M, Kjeldsen-Kragh J, Quayle A, Kalvenes C, Waalen K, Førre O, Natvig JB (1990)
The V delta gene usage by freshly isolated T lymphocytes from synovial fluids in rheumatoid synovitis: a preliminary report
Scand J Immunol, 31 (4), 415-21
PubMed 1692153

Publications 1989

Forterre P, Elie C, Sioud M, Hamal A (1989)
Studies on DNA polymerases and topoisomerases in archaebacteria
Can J Microbiol, 35 (1), 228-33
PubMed 2541877

Quayle A, Kjeldsen-Kragh J, Førre O, Waalen K, Sioud M, Kalvenes C, Natvig JB (1989)
Immunoregulatory T cell subsets and T cell activation in rheumatoid arthritis. A need for analysis on the clonal and molecular level
Springer Semin Immunopathol, 11 (3), 273-87
PubMed 2575800

Sioud M, Forterre P (1989)
Ciprofloxacin and etoposide (VP16) produce a similar pattern of DNA cleavage in a plasmid of an archaebacterium
Biochemistry, 28 (9), 3638-41
PubMed 2751986

Publications 1988

Sioud M, Baldacci G, de Recondo AM, Forterre P (1988)
Novobiocin induces positive supercoiling of small plasmids from halophilic archaebacteria in vivo
Nucleic Acids Res, 16 (4), 1379-91
PubMed 3347494

Sioud M, Baldacci G, de Recondo AM, Forterre P (1988)
Inhibitors of DNA topoisomerase II induce topological changes in an archaebacterial plasmid in vivo
Biochem Pharmacol, 37 (9), 1879-80
PubMed 2837247

Sioud M, Baldacci G, Forterre P, de Recondo AM (1988)
Novobiocin induces accumulation of a single strand of plasmid pGRB-1 in the archaebacterium Halobacterium GRB
Nucleic Acids Res, 16 (16), 7833-42
PubMed 3419901

Sioud M, Possot O, Elie C, Sibold L, Forterre P (1988)
Coumarin and quinolone action in archaebacteria: evidence for the presence of a DNA gyrase-like enzyme
J Bacteriol, 170 (2), 946-53
PubMed 2828337

Publications 1987

Sioud M, Baldacci G, Forterre P, de Recondo AM (1987)
Antitumor drugs inhibit the growth of halophilic archaebacteria
Eur J Biochem, 169 (2), 231-6
PubMed 3121311

Sioud M, Forterre P, de Recondo AM (1987)
Effects of the antitumor drug VP16 (etoposide) on the archaebacterial Halobacterium GRB 1.7 kb plasmid in vivo
Nucleic Acids Res, 15 (20), 8217-34
PubMed 3671082

Publications 1986

Bernard M, Sioud M, Percheron F, Foglietti MJ (1986)
beta-Mannosidase in human serum and urine. A comparative study
Int J Biochem, 18 (11), 1065-8
PubMed 3803698