Publications by Anne Gjøen Simonsen

140 publications found

  1. Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H et al. (2024)
    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
    J Gerontol A Biol Sci Med Sci, 79 (4)
    DOI 10.1093/gerona/glae029, PubMed 38289789
  2. Theriot JA, Simonsen A, Tolić I, Leonetti MD, Mayor S, Bassereau P, Paluch EK, Han J, Covert MW, Mizushima N, Reck-Peterson S, Strasser A, Cheeseman I (2024)
    Cell biology is…
    Cell, 187 (2), 219-224
    DOI 10.1016/j.cell.2023.12.020, PubMed 38242078
  3. Reggiori F, Boya P, da Costa D, Elazar Z, Eskelinen EL, Farrés J, Guettler S, Kraft C, Jungbluth H, Martinez A, Morel E, Pless O, Proikas-Cezanne T, Simonsen A (2022)
    The mechanism of macroautophagy: The movie
    Autophagy Rep, 1 (1), 414-417
    DOI 10.1080/27694127.2022.2096115, PubMed 38106995
  4. Sporbeck K, Haas ML, Pastor-Maldonado CJ, Schüssele DS, Hunter C, Takacs Z, Diogo de Oliveira AL, Franz-Wachtel M, Charsou C, Pfisterer SG, Gubas A, Haller PK, Knorr RL, Kaulich M, Macek B, Eskelinen EL, Simonsen A, Proikas-Cezanne T (2023)
    The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension
    Commun Biol, 6 (1), 872
    DOI 10.1038/s42003-023-05236-9, PubMed 37620393
  5. Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
    TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
    EMBO J, 42 (17), e113105
    DOI 10.15252/embj.2022113105, PubMed 37409525
  6. Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
    Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
    Front Cell Dev Biol, 10, 1022191
    DOI 10.3389/fcell.2022.1022191, PubMed 36619857
  7. Ganley IG, Simonsen A (2022)
    Diversity of mitophagy pathways at a glance
    J Cell Sci, 135 (23)
    DOI 10.1242/jcs.259748, PubMed 36504076
  8. Charsou C, Ng MYW, Simonsen A (2022)
    Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
    Autophagy, 19 (7), 2159-2161
    DOI 10.1080/15548627.2022.2155020, PubMed 36469687
  9. Maestro I, de la Ballina LR, Porras G, Corrochano S, De Lago E, Simonsen A, Boya P, Martinez A (2022)
    Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations
    Int J Mol Sci, 23 (20)
    DOI 10.3390/ijms232012676, PubMed 36293534
  10. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
  11. Simonsen A, Wollert T (2022)
    Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
    Curr Opin Cell Biol, 75, 102064
    DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373
  12. Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
    Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Autophagy, 18 (11), 2547-2560
    DOI 10.1080/15548627.2022.2039535, PubMed 35220892
  13. Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
    STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
    Am J Cancer Res, 12 (1), 327-336
    PubMed 35141021
  14. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  15. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy, 18 (2), 467-469
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  16. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci, 1510 (1), 79-99
    DOI 10.1111/nyas.14745, PubMed 35000205
  17. Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy, 18 (8), 1915-1931
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  18. Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF (2021)
    Autophagy in healthy aging and disease
    Nat Aging, 1 (8), 634-650
    DOI 10.1038/s43587-021-00098-4, PubMed 34901876
  19. Maestro I, de la Ballina LR, Simonsen A, Boya P, Martinez A (2021)
    Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease
    ACS Chem Neurosci, 12 (24), 4512-4523
    DOI 10.1021/acschemneuro.1c00529, PubMed 34846852
  20. Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V (2021)
    Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes
    Cell, 184 (24), 5950-5969.e22
    DOI 10.1016/j.cell.2021.10.017, PubMed 34741801
  21. Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
    Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
    Autophagy, 18 (7), 1486-1502
    DOI 10.1080/15548627.2021.1988359, PubMed 34740308
  22. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  23. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T et al. (2021)
    Autophagy in major human diseases
    EMBO J, 40 (19), e108863
    DOI 10.15252/embj.2021108863, PubMed 34459017
  24. Durgan J, Lystad AH, Sloan K, Carlsson SR, Wilson MI, Marcassa E, Ulferts R, Webster J, Lopez-Clavijo AF, Wakelam MJ, Beale R, Simonsen A, Oxley D, Florey O (2021)
    Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine
    Mol Cell, 81 (9), 2031-2040.e8
    DOI 10.1016/j.molcel.2021.03.020, PubMed 33909989
  25. Ng MYW, Wai T, Simonsen A (2021)
    Quality control of the mitochondrion
    Dev Cell, 56 (7), 881-905
    DOI 10.1016/j.devcel.2021.02.009, PubMed 33662258
  26. Terešak P, Lapao A, Subic N, Boya P, Elazar Z, Simonsen A (2021)
    Regulation of PRKN-independent mitophagy
    Autophagy, 18 (1), 24-39
    DOI 10.1080/15548627.2021.1888244, PubMed 33570005
  27. Corkery DP, Nadeem A, Aung KM, Hassan A, Liu T, Cervantes-Rivera R, Lystad AH, Wang H, Persson K, Puhar A, Simonsen A, Uhlin BE, Wai SN, Wu YW (2021)
    Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy
    J Cell Sci, 134 (5)
    DOI 10.1242/jcs.252015, PubMed 33106317
  28. Melia TJ, Lystad AH, Simonsen A (2020)
    Autophagosome biogenesis: From membrane growth to closure
    J Cell Biol, 219 (6)
    DOI 10.1083/jcb.202002085, PubMed 32357219
  29. Bindesbøll C, Aas A, Ogmundsdottir MH, Pankiv S, Reine T, Zoncu R, Simonsen A (2020)
    NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease
    Sci Rep, 10 (1), 4528
    DOI 10.1038/s41598-020-61352-0, PubMed 32161285
  30. Lotsberg ML, Wnuk-Lipinska K, Terry S, Tan TZ, Lu N, Trachsel-Moncho L, Røsland GV, Siraji MI, Hellesøy M, Rayford A, Jacobsen K, Ditzel HJ, Vintermyr OK, Bivona TG, Minna J, Brekken RA, Baguley B, Micklem D, Akslen LA, Gausdal G, Simonsen A, Thiery JP, Chouaib S, Lorens JB, Engelsen AST (2020)
    AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells
    J Thorac Oncol, 15 (6), 973-999
    DOI 10.1016/j.jtho.2020.01.015, PubMed 32018052
  31. Gawel K, Turski WA, van der Ent W, Mathai BJ, Kirstein-Smardzewska KJ, Simonsen A, Esguerra CV (2019)
    Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene
    Mol Neurobiol, 57 (4), 1904-1916
    DOI 10.1007/s12035-019-01860-x, PubMed 31875924
  32. Simonsen A, Sánchez-Heredia JD, Saarinen SA, Ardenkjær-Larsen JH, Schliesser A, Polzik ES (2019)
    Magnetic resonance imaging with optical preamplification and detection
    Sci Rep, 9 (1), 18173
    DOI 10.1038/s41598-019-54200-3, PubMed 31796770
  33. Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G, Dikic I (2019)
    TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease
    EMBO Rep, 21 (1), e48317
    DOI 10.15252/embr.201948317, PubMed 31709703
  34. Herzog LK, Kevei É, Marchante R, Böttcher C, Bindesbøll C, Lystad AH, Pfeiffer A, Gierisch ME, Salomons FA, Simonsen A, Hoppe T, Dantuma NP (2019)
    The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy
    Aging Cell, 19 (1), e13051
    DOI 10.1111/acel.13051, PubMed 31625269
  35. Lystad AH, Simonsen A (2019)
    Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery
    Cells, 8 (9)
    DOI 10.3390/cells8090973, PubMed 31450711
  36. Rahman MA, Gras Navarro A, Brekke J, Engelsen A, Bindesbøll C, Sarowar S, Bahador M, Bifulco E, Goplen D, Waha A, Lie SA, Gjertsen BT, Selheim F, Enger PØ, Simonsen A, Chekenya M (2019)
    Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival
    Br J Cancer, 121 (7), 545-555
    DOI 10.1038/s41416-019-0551-1, PubMed 31413318
  37. Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
    ESCRT-mediated phagophore sealing during mitophagy
    Autophagy, 16 (5), 826-841
    DOI 10.1080/15548627.2019.1639301, PubMed 31366282
  38. Gras Navarro A, Espedal H, Joseph JV, Trachsel-Moncho L, Bahador M, Gjertsen BT, Kristoffersen EK, Simonsen A, Miletic H, Enger PØ, Rahman MA, Chekenya M (2019)
    Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival
    Cancers (Basel), 11 (7)
    DOI 10.3390/cancers11070996, PubMed 31319548
  39. Abudu YP, Pankiv S, Mathai BJ, Lamark T, Johansen T, Simonsen A (2019)
    NIPSNAP1 and NIPSNAP2 act as "eat me" signals to allow sustained recruitment of autophagy receptors during mitophagy
    Autophagy, 15 (10), 1845-1847
    DOI 10.1080/15548627.2019.1637642, PubMed 31251109
  40. Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Liu M, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Weaver J, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Jo EK, Johansen T et al. (2019)
    Autophagy, Inflammation, and Metabolism (AIM) Center in its second year
    Autophagy, 15 (10), 1829-1833
    DOI 10.1080/15548627.2019.1634444, PubMed 31234750
  41. de la Ballina LR, Munson MJ, Simonsen A (2019)
    Lipids and Lipid-Binding Proteins in Selective Autophagy
    J Mol Biol, 432 (1), 135-159
    DOI 10.1016/j.jmb.2019.05.051, PubMed 31202884
  42. Lystad AH, Carlsson SR, Simonsen A (2019)
    Toward the function of mammalian ATG12-ATG5-ATG16L1 complex in autophagy and related processes
    Autophagy, 15 (8), 1485-1486
    DOI 10.1080/15548627.2019.1618100, PubMed 31122169
  43. Princely Abudu Y, Pankiv S, Mathai BJ, Håkon Lystad A, Bindesbøll C, Brenne HB, Yoke Wui Ng M, Thiede B, Yamamoto A, Mutugi Nthiga T, Lamark T, Esguerra CV, Johansen T, Simonsen A (2019)
    NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy
    Dev Cell, 49 (4), 509-525.e12
    DOI 10.1016/j.devcel.2019.03.013, PubMed 30982665
  44. Lystad AH, Carlsson SR, de la Ballina LR, Kauffman KJ, Nag S, Yoshimori T, Melia TJ, Simonsen A (2019)
    Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes
    Nat Cell Biol, 21 (3), 372-383
    DOI 10.1038/s41556-019-0274-9, PubMed 30778222
  45. Chaurasia M, Gupta S, Das A, Dwarakanath BS, Simonsen A, Sharma K (2019)
    Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy
    Autophagy, 15 (8), 1391-1406
    DOI 10.1080/15548627.2019.1582973, PubMed 30773986
  46. Möller K, Sigurbjornsdottir S, Arnthorsson AO, Pogenberg V, Dilshat R, Fock V, Brynjolfsdottir SH, Bindesboll C, Bessadottir M, Ogmundsdottir HM, Simonsen A, Larue L, Wilmanns M, Thorsson V, Steingrimsson E, Ogmundsdottir MH (2019)
    MITF has a central role in regulating starvation-induced autophagy in melanoma
    Sci Rep, 9 (1), 1055
    DOI 10.1038/s41598-018-37522-6, PubMed 30705290
  47. Ogmundsdottir MH, Fock V, Sooman L, Pogenberg V, Dilshat R, Bindesbøll C, Ogmundsdottir HM, Simonsen A, Wilmanns M, Steingrimsson E (2018)
    Publisher Correction: A short isoform of ATG7 fails to lipidate LC3/GABARAP
    Sci Rep, 8 (1), 17194
    DOI 10.1038/s41598-018-35540-y, PubMed 30446765
  48. Johannessen TC, Hasan-Olive MM, Zhu H, Denisova O, Grudic A, Latif MA, Saed H, Varughese JK, Røsland GV, Yang N, Sundstrøm T, Nordal A, Tronstad KJ, Wang J, Lund-Johansen M, Simonsen A, Janji B, Westermarck J, Bjerkvig R, Prestegarden L (2018)
    Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide
    Int J Cancer, 144 (7), 1735-1745
    DOI 10.1002/ijc.31912, PubMed 30289977
  49. Ogmundsdottir MH, Fock V, Sooman L, Pogenberg V, Dilshat R, Bindesbøll C, Ogmundsdottir HM, Simonsen A, Wilmanns M, Steingrimsson E (2018)
    A short isoform of ATG7 fails to lipidate LC3/GABARAP
    Sci Rep, 8 (1), 14391
    DOI 10.1038/s41598-018-32694-7, PubMed 30258106
  50. Kraft C, Boya P, Codogno P, Elazar Z, Eskelinen EL, Farrés J, Kirkin V, Jungbluth H, Martinez A, Pless O, Primard C, Proikas-Cezanne T, Simonsen A, Reggiori F (2018)
    Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
    Autophagy, 15 (2), 347-351
    DOI 10.1080/15548627.2018.1515532, PubMed 30176150
  51. Simonsen A (2018)
    Confidence to go the way science takes you
    Nat Cell Biol, 20 (9), 1009
    DOI 10.1038/s41556-018-0156-6, PubMed 30154563
  52. Skah S, Richartz N, Duthil E, Gilljam KM, Bindesbøll C, Naderi EH, Eriksen AB, Ruud E, Dirdal MM, Simonsen A, Blomhoff HK (2018)
    cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53
    Oncotarget, 9 (54), 30434-30449
    DOI 10.18632/oncotarget.25758, PubMed 30100998
  53. Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Hotamisligi G, Jäättelä M, Jo EK, Johansen T, Juhász G, Kimchi A et al. (2018)
    Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
    Autophagy, 14 (6), 925-929
    DOI 10.1080/15548627.2018.1465784, PubMed 29938597
  54. SenGupta T, Torgersen ML, Kassahun H, Vellai T, Simonsen A, Nilsen H (2018)
    Publisher Correction: Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy
    Nat Commun, 9, 16206
    DOI 10.1038/ncomms16206, PubMed 29595188
  55. Søreng K, Munson MJ, Lamb CA, Bjørndal GT, Pankiv S, Carlsson SR, Tooze SA, Simonsen A (2018)
    SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2
    EMBO Rep, 19 (4)
    DOI 10.15252/embr.201744837, PubMed 29437695
  56. Søreng K, Neufeld TP, Simonsen A (2017)
    Membrane Trafficking in Autophagy
    Int Rev Cell Mol Biol, 336, 1-92
    DOI 10.1016/bs.ircmb.2017.07.001, PubMed 29413888
  57. Schläfli AM, Isakson P, Garattini E, Simonsen A, Tschan MP (2017)
    The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells
    Sci Rep, 7 (1), 12980
    DOI 10.1038/s41598-017-12734-4, PubMed 29021535
  58. Kjos I, Borg Distefano M, Sætre F, Repnik U, Holland P, Jones AT, Engedal N, Simonsen A, Bakke O, Progida C (2017)
    Rab7b modulates autophagic flux by interacting with Atg4B
    EMBO Rep, 18 (10), 1727-1739
    DOI 10.15252/embr.201744069, PubMed 28835545
  59. Mathai BJ, Meijer AH, Simonsen A (2017)
    Studying Autophagy in Zebrafish
    Cells, 6 (3)
    DOI 10.3390/cells6030021, PubMed 28698482
  60. Galluzzi L, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cecconi F, Choi AM, Chu CT, Codogno P, Colombo MI, Cuervo AM, Debnath J, Deretic V, Dikic I, Eskelinen EL, Fimia GM, Fulda S, Gewirtz DA, Green DR, Hansen M, Harper JW, Jäättelä M, Johansen T, Juhasz G, Kimmelman AC et al. (2017)
    Molecular definitions of autophagy and related processes
    EMBO J, 36 (13), 1811-1836
    DOI 10.15252/embj.201796697, PubMed 28596378
  61. Søreng K, Knævelsrud H, Holland P, Simonsen A (2017)
    HS1BP3 inhibits autophagy by regulation of PLD1
    Autophagy, 13 (5), 985-986
    DOI 10.1080/15548627.2017.1291483, PubMed 28318354
  62. Aas A, Isakson P, Bindesbøll C, Alemu EA, Klungland A, Simonsen A (2017)
    Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
    PLoS One, 12 (3), e0168182
    DOI 10.1371/journal.pone.0168182, PubMed 28288181
  63. Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
    HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
    Nat Commun, 7, 13889
    DOI 10.1038/ncomms13889, PubMed 28004827
  64. Simonsen A (2016)
    [Self-devouring prolongs life]
    Tidsskr Nor Laegeforen, 136 (22), 1873
    DOI 10.4045/tidsskr.16.0908, PubMed 27929545
  65. Dragich JM, Kuwajima T, Hirose-Ikeda M, Yoon MS, Eenjes E, Bosco JR, Fox LM, Lystad AH, Oo TF, Yarygina O, Mita T, Waguri S, Ichimura Y, Komatsu M, Simonsen A, Burke RE, Mason CA, Yamamoto A (2016)
    Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain
    Elife, 5
    DOI 10.7554/eLife.14810, PubMed 27648578
  66. Shatz O, Holland P, Elazar Z, Simonsen A (2016)
    Complex Relations Between Phospholipids, Autophagy, and Neutral Lipids
    Trends Biochem Sci, 41 (11), 907-923
    DOI 10.1016/j.tibs.2016.08.001, PubMed 27595473
  67. Lystad AH, Simonsen A (2016)
    Phosphoinositide-binding proteins in autophagy
    FEBS Lett, 590 (15), 2454-68
    DOI 10.1002/1873-3468.12286, PubMed 27391591
  68. Andersen AN, Landsverk OJ, Simonsen A, Bogen B, Corthay A, Øynebråten I (2016)
    Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
    Front Immunol, 7, 167
    DOI 10.3389/fimmu.2016.00167, PubMed 27242780
  69. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM et al. (2016)
    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
    Autophagy, 12 (1), 1-222
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