Hanne Scholz
Position: Senior scientist, MSc, PhD
Phone: +47 23073526
Email:
 

Publications 2017

Abadpour S, Göpel SO, Schive SW, Korsgren O, Foss A, Scholz H (2017)
Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis
Sci Rep, 7 (1), 1575
PubMed 28484241

Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V (2017)
Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates
Physiol Rep, 5 (19)
PubMed 29038359

Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H (2017)
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
PubMed 28713640

Schuetz C, Anazawa T, Cross SE, Labriola L, Meier RPH, Redfield RR, Scholz H, Stock PG, Zammit NW, IPITA YIC Young Investigator Committee (2017)
ß cell replacement therapy: the next 10 years
Transplantation (in press)
PubMed 28885496

Vethe H, Bjørlykke Y, Ghila LM, Paulo JA, Scholz H, Gygi SP, Chera S, Ræder H (2017)
Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells
Sci Rep, 7 (1), 4780
PubMed 28684784

Publications 2016

Hals IK, Singh R, Ma Z, Scholz H, Björklund A, Grill V (2016)
Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability
Islets, 8 (6), 165-176
PubMed 27763807

Halvorsen B, Santilli F, Scholz H, Sahraoui A, Gulseth HL, Wium C, Lattanzio S, Formoso G, Di Fulvio P, Otterdal K, Retterstøl K, Holven KB, Gregersen I, Stavik B, Bjerkeli V, Michelsen AE, Ueland T, Liani R, Davi G, Aukrust P (2016)
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
Diabetologia, 59 (10), 2134-44
PubMed 27421726

Kloster-Jensen K, Sahraoui A, Vethe NT, Korsgren O, Bergan S, Foss A, Scholz H (2016)
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids
J Diabetes Res, 2016, 4196460
PubMed 26885529

Schive SW, Foss A, Sahraoui A, Kloster-Jensen K, Hafsahl G, Kvalheim G, Lundgren T, von Zur-Mühlen B, Felldin M, Rafael E, Lempinen M, Korsgren O, Jenssen TG, Mishra V, Scholz H (2016)
Cost and clinical outcome of islet transplantation in Norway 2010-2015
Clin Transplant, 31 (1)
PubMed 27862341

Publications 2015

Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015)
Mitochondrial Respiration in Insulin-Producing β-Cells: General Characteristics and Adaptive Effects of Hypoxia
PLoS One, 10 (9), e0138558
PubMed 26401848

Kloster-Jensen K, Vethe NT, Bremer S, Abadpour S, Korsgren O, Foss A, Bergan S, Scholz H (2015)
Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro
Transpl Int, 28 (10), 1152-61
PubMed 26046470

Sahraoui A, Winzell MS, Gorman T, Smith DM, Skrtic S, Hoeyem M, Abadpour S, Johansson L, Korsgren O, Foss A, Scholz H (2015)
The effects of exendin-4 treatment on graft failure: an animal study using a novel re-vascularized minimal human islet transplant model
PLoS One, 10 (3), e0121204
PubMed 25793295

Schive SW, Scholz H, Sahraoui A, Kloster-Jensen K, Hafsahl G, Korsgren O, Foss A, Jenssen TG (2015)
Graft function 1 year after pregnancy in an islet-transplanted patient
Transpl Int, 28 (10), 1235-9
PubMed 25903157

Publications 2014

Halvorsen B, Holm S, Yndestad A, Scholz H, Sagen EL, Nebb H, Holven KB, Dahl TB, Aukrust P (2014)
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α
Biochem Biophys Res Commun, 450 (4), 1525-30
PubMed 25035925

Publications 2013

Lekva T, Bollerslev J, Sahraoui A, Scholz H, Bøyum H, Evang JA, Godang K, Aukrust P, Ueland T (2013)
Thioredoxin interacting protein is a potential regulator of glucose and energy homeostasis in endogenous Cushing's syndrome
PLoS One, 8 (5), e64247
PubMed 23691179

Sahraoui A, Kloster-Jensen K, Ueland T, Korsgren O, Foss A, Scholz H (2013)
Anakinra and tocilizumab enhance survival and function of human islets during culture: implications for clinical islet transplantation
Cell Transplant, 23 (10), 1199-211
PubMed 23635711

Shi JH, Scholz H, Huitfeldt HS, Line PD (2013)
The effect of hepatic progenitor cells on experimental hepatocellular carcinoma in the regenerating liver
Scand J Gastroenterol, 49 (1), 99-108
PubMed 24188385

Publications 2012

Basu A, Alaupovic P, Wu M, Jenkins AJ, Yu Y, Nankervis AJ, Hanssen KF, Scholz H, Henriksen T, Lorentzen B, Clausen T, Garg SK, Menard MK, Hammad SM, Scardo JA, Stanley JR, Dashti A, Aston CE, Lyons TJ (2012)
Plasma lipoproteins and preeclampsia in women with type 1 diabetes: a prospective study
J Clin Endocrinol Metab, 97 (5), 1752-62
PubMed 22438226

Shi JH, Liu SZ, Wierød L, Scholz H, Anmarkrud JA, Huitfeldt HS, Zhang SJ, Line PD (2012)
RAF-targeted therapy for hepatocellular carcinoma in the regenerating liver
J Surg Oncol, 107 (4), 393-401
PubMed 22927239

Yu Y, Hanssen KF, Kalyanaraman V, Chirindel A, Jenkins AJ, Nankervis AJ, Torjesen PA, Scholz H, Henriksen T, Lorentzen B, Garg SK, Menard MK, Hammad SM, Scardo JA, Stanley JR, Wu M, Basu A, Aston CE, Lyons TJ (2012)
Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes
BJOG, 119 (12), 1512-20
PubMed 22900949

Publications 2011

Andersen GØ, Ueland T, Knudsen EC, Scholz H, Yndestad A, Sahraoui A, Smith C, Lekva T, Otterdal K, Halvorsen B, Seljeflot I, Aukrust P (2011)
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
Diabetes, 60 (5), 1544-51
PubMed 21464440

Azar M, Basu A, Jenkins AJ, Nankervis AJ, Hanssen KF, Scholz H, Henriksen T, Garg SK, Hammad SM, Scardo JA, Aston CE, Lyons TJ (2011)
Serum carotenoids and fat-soluble vitamins in women with type 1 diabetes and preeclampsia: a longitudinal study
Diabetes Care, 34 (6), 1258-64
PubMed 21498785

Publications 2010

Lund T, Mangsbo SM, Scholz H, Gjorstrup P, Tötterman TH, Korsgren O, Foss A (2010)
Resolvin E1 reduces proinflammatory markers in human pancreatic islets in vitro
Exp Clin Endocrinol Diabetes, 118 (4), 237-44
PubMed 20119897

Publications 2009

Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A (2009)
The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro
Diabetologia, 52 (7), 1352-62
PubMed 19415233

Ueland T, Fougner SL, Godang K, Lekva T, Schurgers LJ, Scholz H, Halvorsen B, Schreiner T, Aukrust P, Bollerslev J (2009)
Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly
J Clin Endocrinol Metab, 95 (1), 361-8
PubMed 19880791

Ueland T, Fougner SL, Godang K, Lekva T, Schurgers LJ, Scholz H, Halvorsen B, Schreiner T, Aukrust PL, Bollerslev J (2009)
Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly
Endocr Rev, 30 (7), 927
PubMed 28199500

Publications 2008

Lund T, Fosby B, Korsgren O, Scholz H, Foss A (2008)
Glucocorticoids reduce pro-inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo
Transpl Int, 21 (7), 669-78
PubMed 18346012

Lund T, Korsgren O, Aursnes IA, Scholz H, Foss A (2008)
Sustained reversal of diabetes following islet transplantation to striated musculature in the rat
J Surg Res, 160 (1), 145-54
PubMed 19394966

Publications 2006

Halvorsen B, Waehre T, Scholz H, Damås JK, Yndestad A, Aukrust P (2006)
Role of interleukin-10 in atherogenesis and plaque stabilization
Future Cardiol, 2 (1), 75-83
PubMed 19804134

Sandberg WJ, Yndestad A, Øie E, Smith C, Ueland T, Ovchinnikova O, Robertson AK, Müller F, Semb AG, Scholz H, Andreassen AK, Gullestad L, Damås JK, Frøland SS, Hansson GK, Halvorsen B, Aukrust P (2006)
Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
Arterioscler Thromb Vasc Biol, 26 (4), 857-63
PubMed 16424351

Smith C, Damås JK, Otterdal K, Øie E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Frøland SS, Hansson GK, Aukrust P (2006)
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation
J Am Coll Cardiol, 48 (8), 1591-9
PubMed 17045893

Publications 2005

Scholz H, Sandberg W, Damås JK, Smith C, Andreassen AK, Gullestad L, Frøland SS, Yndestad A, Aukrust P, Halvorsen B (2005)
Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis
Circulation, 112 (14), 2121-9
PubMed 16186421

Publications 2004

Halvorsen B, Waehre T, Scholz H, Clausen OP, von der Thüsen JH, Müller F, Heimli H, Tonstad S, Hall C, Frøland SS, Biessen EA, Damås JK, Aukrust P (2004)
Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms
J Lipid Res, 46 (2), 211-9
PubMed 15547296

Smith C, Yndestad A, Halvorsen B, Ueland T, Waehre T, Otterdal K, Scholz H, Endresen K, Gullestad L, Frøland SS, Damås JK, Aukrust P (2004)
Potential anti-inflammatory role of activin A in acute coronary syndromes
J Am Coll Cardiol, 44 (2), 369-75
PubMed 15261933

Publications 2003

Holven KB, Scholz H, Halvorsen B, Aukrust P, Ose L, Nenseter MS (2003)
Hyperhomocysteinemic subjects have enhanced expression of lectin-like oxidized LDL receptor-1 in mononuclear cells
J Nutr, 133 (11), 3588-91
PubMed 14608078

Scholz H, Yndestad A, Damås JK, Waehre T, Tonstad S, Aukrust P, Halvorsen B (2003)
8-isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases
Cardiovasc Res, 59 (4), 945-54
PubMed 14553834