Lars Wik

  • Senior researcher, Senior Physician; MD, PhD
  • +47 23 02 62 14

Senior Consultant of Anaesthesiology and Senior Researcher at Oslo University Hospital and NAKOS. Since 1985 Dr Wik has been active in conducting clinical and experimental research into mechanical Cardiopulmonary Resuscitation (CPR). Together with Professor Steen he established the experimental cardiac arrest program at the Institute of Experimental Medical Research at Ullevål University Hospital in the beginning of 1990’s and were crucial for implementing randomized clinical outcome studies utilizing the infrastructure of the prehospital Emergency Medicine Service and Hospitals in the Oslo area. Several studies have changed the International CPR Guidelines. The combination of studies exploring different experimental CPR methods in the animal lab, didactic CPR performance, clinical outcome and hemodynamic studies of patients is unique and document a broad approach to save more lives. Dr Wik was the Principal Investigator (PI) for the International Circulation Improving Resuscitation Care (CIRC) randomized controlled trial and led several clinical outcome studies (The SISTER study, CPR before defibrillation, IV Yes/No,) that have changed CPR Guidelines. Innovative studies related to avalanche and trauma have also documented how to save more lives. During the last years Dr Wik has been the PI for the first mechanical clinical active compression decompression studies (LUCAS 2 AD studies). During the last few years he has been influential in designing and performing randomized studies regarding use of biosensors and signal processing in prehospital care.   

Dr Wik’s work has generated contributions to about 130 publications in top ranked journals resulting in several invitations worldwide to present at congresses. 

Dr Wik actively practices clinical pre-hospital emergency medicine (last 40 years), regular shifts at Oslo University Hospital Anaesthesia department, and conducts advanced research on cardiac arrest and trauma while working with the rapid response car in Oslo. Dr Wik also holds several patents related to Emergency Medicine technology licensed to International Manufactories. 

Lars Wik - Cristin

Lars Wik | ResearchGate


Publications 2024

Bray J, Rea T, Parnia S, Morgan RW, Wik L, Sutton R (2024)
Wolf Creek XVII Part 6: Physiology-Guided CPR
Resusc Plus, 18, 100589
DOI 10.1016/j.resplu.2024.100589, PubMed 38444864

Gentile FR, Wik L, Isasi I, Baldi E, Aramendi E, Steen-Hansen JE, Fasolino A, Compagnoni S, Contri E, Palo A, Primi R, Bendotti S, Currao A, Quilico F, Vicini Scajola L, Lopiano C, Savastano S (2024)
Amplitude spectral area of ventricular fibrillation can discriminate survival of patients with out-of-hospital cardiac arrest
Front Cardiovasc Med, 11, 1336291
DOI 10.3389/fcvm.2024.1336291, PubMed 38380178

Svensøy JN, Alonso E, Elola A, Bjørnerheim R, Ræder J, Aramendi E, Wik L (2024)
Cardiac output estimation using ballistocardiography: a feasibility study in healthy subjects
Sci Rep, 14 (1), 1671
DOI 10.1038/s41598-024-52300-3, PubMed 38238507

Publications 2023

Gentile FR, Wik L, Aramendi E, Baldi E, Isasi I, Steen-Hansen JE, Compagnoni S, Fasolino A, Contri E, Palo A, Primi R, Bendotti S, Currao A, Savastano S (2023)
aMplitude spectral area of ventricular fibrillation and amiOdarone Study in patients with out-of-hospital cArdIaC arrest. The MOSAIC study
Front Cardiovasc Med, 10, 1179815
DOI 10.3389/fcvm.2023.1179815, PubMed 37255711

Gentile FR, Wik L, Isasi I, Baldi E, Aramendi E, Steen-Hansen JE, Fasolino A, Compagnoni S, Contri E, Palo A, Primi R, Bendotti S, Currao A, Quilico F, Vicini Scajola L, Lopiano C, Savastano S (2023)
Amplitude spectral area of ventricular fibrillation and defibrillation success at low energy in out-of-hospital cardiac arrest
Intern Emerg Med, 18 (8), 2397-2405
DOI 10.1007/s11739-023-03386-6, PubMed 37556074

Olasveengen TM, Skåre C, Skjerven-Martinsen M, Hoff-Olsen P, Kramer-Johansen J, Hoff Nordum F, Eriksen M, Anderas Norseng P, Wik L (2023)
Lung tissue injury and hemodynamic effects of ventilations synchronized or unsynchronized to continuous chest compressions in a porcine cardiac arrest model
Resusc Plus, 17, 100530
DOI 10.1016/j.resplu.2023.100530, PubMed 38155976

Petrovich P, Berve PO, Barth-Heyerdahl Roald B, Wahl Kongsgård H, Stray-Pedersen A, Kramer-Johansen J, Wik L (2023)
Injuries associated with mechanical chest compressions and active decompressions after out-of-hospital cardiac arrest: A subgroup analysis of non-survivors from a randomized study
Resusc Plus, 13, 100362
DOI 10.1016/j.resplu.2023.100362, PubMed 36798487

Ruggeri L, Fumagalli F, Bernasconi F, Semeraro F, Meessen JMTA, Blanda A, Migliari M, Magliocca A, Gordini G, Fumagalli R, Sechi G, Pesenti A, Skrifvars MB, Li Y, Latini R, Wik L, Ristagno G (2023)
Amplitude Spectrum Area of ventricular fibrillation to guide defibrillation: a small open-label, pseudo-randomized controlled multicenter trial
EBioMedicine, 90, 104544
DOI 10.1016/j.ebiom.2023.104544, PubMed 36977371

Publications 2022

Steinberg MF, Olsen JA, Persse D, Souders CM, Wik L (2022)
Efficacy of defibrillator pads placement during ventricular arrhythmias, a before and after analysis
Resuscitation, 174, 16-19
DOI 10.1016/j.resuscitation.2022.03.004, PubMed 35276312

Wik L, Brattebø G, Østerås Ø, Assmus J, Irusta U, Aramendi E, Mydske S, Skaalhegg T, Skaiaa SC, Thomassen Ø (2022)
Physiological effects of providing supplemental air for avalanche victims. A randomised trial
Resuscitation, 172, 38-46
DOI 10.1016/j.resuscitation.2022.01.007, PubMed 35063621

Publications 2021

Berve PO, Hardig BM, Skålhegg T, Kongsgaard H, Kramer-Johansen J, Wik L (2021)
Mechanical active compression-decompression versus standard mechanical cardiopulmonary resuscitation: A randomised haemodynamic out-of-hospital cardiac arrest study
Resuscitation, 170, 1-10
DOI 10.1016/j.resuscitation.2021.10.026, PubMed 34710550

Elola A, Aramendi E, Irusta U, Berve PO, Wik L (2021)
Multimodal Algorithms for the Classification of Circulation States During Out-of-Hospital Cardiac Arrest
IEEE Trans Biomed Eng, 68 (6), 1913-1922
DOI 10.1109/TBME.2020.3030216, PubMed 33044927

Publications 2020

Eftestol T, Stokka SE, Kvaloy JT, Rad AB, Irusta U, Aramendi E, Alonso E, Nordseth T, Skogvoll E, Wik L, Kramer-Johansen J (2020)
A Probabilistic Function to Model the Relationship between Quality of Chest Compressions and the Physiological Response for Patients in Cardiac Arrest
DOI 10.22489/CinC.2020.073

Isasi I, Irusta U, Aramendi E, Eftestøl T, Kramer-Johansen J, Wik L (2020)
Rhythm Analysis during Cardiopulmonary Resuscitation Using Convolutional Neural Networks
Entropy (Basel), 22 (6)
DOI 10.3390/e22060595, PubMed 33286367

Isasi I, Irusta U, Aramendi E, Olsen JA, Wik L (2020)
Detection of Shockable Rhythms Using Convolutional Neural Networks During Chest Compressions Provided by a Load Distributing Band
DOI 10.22489/CinC.2020.045

Lasa H, Irusta U, Eftestol T, Aramendi E, Rad AB, Kramer-Johansen J, Wik L (2020)
Multimodal Biosignal Analysis Algorithm for the Classification of Cardiac Rhythms During Resuscitation
DOI 10.22489/CinC.2020.347

Publications 2019

Berve PO, Irusta U, Kramer-Johansen J, Skålhegg T, Kongsgård HW, Brunborg C, Aramendi E, Wik L (2019)
Transthoracic Impedance Measured with Defibrillator Pads-New Interpretations of Signal Change Induced by Ventilations
J Clin Med, 8 (5)
DOI 10.3390/jcm8050724, PubMed 31121817

Isasi I, Irusta U, Elola A, Aramendi E, Eftestol T, Kramer-Johansen J, Wik L (2019)
A Robust Machine Learning Architecture for a Reliable ECG Rhythm Analysis during CPR
Annu Int Conf IEEE Eng Med Biol Soc, 2019, 1903-1907
DOI 10.1109/EMBC.2019.8856784, PubMed 31946270

Isasi I, Irusta U, Elola A, Aramendi E, Eftestol T, Kramer-Johansen J, Wik L (2019)
A Robust Machine Learning Architecture for a Reliable ECG Rhythm Analysis during CPR
IEEE ENG MED BIO, 1903-1907

Isasi I, Irusta U, Rad AB, Aramendi E, Zabihi M, Eftestol T, Kramer-Johansen J, Wik L (2019)
Automatic Cardiac Rhythm Classification With Concurrent Manual Chest Compressions
IEEE Access, 7, 115147-115159
DOI 10.1109/ACCESS.2019.2935096

Nas J, Kleinnibbelink G, Hannink G, Navarese EP, van Royen N, de Boer MJ, Wik L, Bonnes JL, Brouwer MA (2019)
Diagnostic performance of the basic and advanced life support termination of resuscitation rules: A systematic review and diagnostic meta-analysis
Resuscitation, 148, 3-13
DOI 10.1016/j.resuscitation.2019.12.016, PubMed 31887367

Olsen JA, Brunborg C, Steinberg M, Persse D, Sterz F, Lozano M, Westfall M, van Grunsven PM, Lerner EB, Wik L (2019)
Survival to hospital discharge with biphasic fixed 360 joules versus 200 escalating to 360 joules defibrillation strategies in out-of-hospital cardiac arrest of presumed cardiac etiology
Resuscitation, 136, 112-118
DOI 10.1016/j.resuscitation.2019.01.020, PubMed 30708074

Picon A, Irusta U, Álvarez-Gila A, Aramendi E, Alonso-Atienza F, Figuera C, Ayala U, Garrote E, Wik L, Kramer-Johansen J, Eftestøl T (2019)
Mixed convolutional and long short-term memory network for the detection of lethal ventricular arrhythmia
PLoS One, 14 (5), e0216756
DOI 10.1371/journal.pone.0216756, PubMed 31107876

Skjeflo GW, Skogvoll E, Loennechen JP, Olasveengen TM, Wik L, Nordseth T (2019)
The effect of intravenous adrenaline on electrocardiographic changes during resuscitation in patients with initial pulseless electrical activity in out of hospital cardiac arrest
Resuscitation, 136, 119-125
DOI 10.1016/j.resuscitation.2019.01.021, PubMed 30708075

Publications 2018

Isasi I, Rad AB, Irusta U, Zabihi M, Aramendi E, Eftestol T, Kramer-Johansen J, Wik L (2018)
ECG Rhythm Analysis During Manual Chest Compressions Using an Artefact Removal Filter and Random Forest Classifiers
DOI 10.22489/CinC.2018.202

Steinberg MT, Olsen JA, Eriksen M, Neset A, Norseng PA, Kramer-Johansen J, Hardig BM, Wik L (2018)
Haemodynamic outcomes during piston-based mechanical CPR with or without active decompression in a porcine model of cardiac arrest
Scand J Trauma Resusc Emerg Med, 26 (1), 31
DOI 10.1186/s13049-018-0496-z, PubMed 29690910

Publications 2017

Nürnberger A, Herkner H, Sterz F, Olsen JA, Lozano M, van Grunsven PM, Lerner EB, Persse D, Malzer R, Brouwer MA, Westfall M, Souders CM, Travis DT, Herken UR, Wik L (2017)
Observed survival benefit of mild therapeutic hypothermia reanalysing the Circulation Improving Resuscitation Care trial
Eur J Clin Invest, 47 (6), 439-446
DOI 10.1111/eci.12759, PubMed 28407232

Ottestad W, Bredmose PB, Berve PO, Stave H, Farstad G, Wik L, Sandberg M (2017)
[Not Available]
Tidsskr Nor Laegeforen, 137 (3), 169
DOI 10.4045/tidsskr.17.0087, PubMed 28181746

Ottestad W, Bredmose PB, Berve PO, Stave H, Farstad G, Wik L, Sandberg M (2017)
[Not Available]
Tidsskr Nor Laegeforen, 137 (9), 603-604
DOI 10.4045/tidsskr.17.0304, PubMed 28468468

Ottestad W, Bredmose PB, Berve PO, Stave H, Farstad G, Wik L, Sandberg M (2017)
Prehospital thoracotomy for traumatic cardiac arrest
Tidsskr. Nor. Laegeforen., 137 (3), 169

Ottestad W, Bredmose PB, Berve PO, Stave H, Farstad G, Wik L, Sandberg M (2017)
Ethics and aesthetics in prehospital thoracotomy
Tidsskr. Nor. Laegeforen., 137 (9), 603-604

Rad AB, Eftestol T, Engan K, Irusta U, Kvaloy JT, Kramer-Johansen J, Wik L, Katsaggelos AK (2017)
ECG-Based Classification of Resuscitation Cardiac Rhythms for Retrospective Data Analysis
IEEE Trans Biomed Eng, 64 (10), 2411-2418
DOI 10.1109/TBME.2017.2688380, PubMed 28371771

Rad AB, Eftestøl T, Irusta U, Kvaløy JT, Wik L, Kramer-Johansen J, Katsaggelos AK, Engan K (2017)
An automatic system for the comprehensive retrospective analysis of cardiac rhythms in resuscitation episodes
Resuscitation, 122, 6-12
DOI 10.1016/j.resuscitation.2017.11.035, PubMed 29122647

Thomassen O, Skaiaa SC, Assmuss J, Østerås Ø, Heltne JK, Wik L, Brattebo G (2017)
Mountain rescue cardiopulmonary resuscitation: a comparison between manual and mechanical chest compressions during manikin cardio resuscitation
Emerg Med J, 34 (9), 573-577
DOI 10.1136/emermed-2016-206323, PubMed 28476730

Publications 2016

Figuera C, Irusta U, Morgado E, Aramendi E, Ayala U, Wik L, Kramer-Johansen J, Eftestøl T, Alonso-Atienza F (2016)
Machine Learning Techniques for the Detection of Shockable Rhythms in Automated External Defibrillators
PLoS One, 11 (7), e0159654
DOI 10.1371/journal.pone.0159654, PubMed 27441719

Kjellemo H, Hansen AE, Øines DA, Nilsen TO, Wik L (2016)
Pediatric Cardiac Arrest Due to Trauma
Prehosp Emerg Care, 20 (3), 425-31
DOI 10.3109/10903127.2015.1111479, PubMed 26930137

Ottestad W, Bredmose PB, Berve PO, Stave H, Farstad G, Wik L, Sandberg M (2016)
Prehospital thoracotomy for traumatic cardiac arrest
Tidsskr Nor Laegeforen, 136 (23-24), 1964-1965
DOI 10.4045/tidsskr.16.0798, PubMed 28004542

Rad AB, Engan K, Katsaggelos AK, Kvaløy JT, Wik L, Kramer-Johansen J, Irusta U, Eftestøl T (2016)
Automatic cardiac rhythm interpretation during resuscitation
Resuscitation, 102, 44-50
DOI 10.1016/j.resuscitation.2016.01.015, PubMed 26891862

Steinberg MT, Olsen JA, Brunborg C, Persse D, Sterz F, Lozano M, Westfall M, Travis DT, Lerner EB, Wik L (2016)
Defibrillation success during different phases of the mechanical chest compression cycle
Resuscitation, 103, 99-105
DOI 10.1016/j.resuscitation.2016.01.031, PubMed 26875991

Wik L (2016)
Near-infrared spectroscopy during cardiopulmonary resuscitation and after restoration of spontaneous circulation: a valid technology?
Curr Opin Crit Care, 22 (3), 191-8
DOI 10.1097/MCC.0000000000000301, PubMed 27054625

Wik L, Olsen JA, Persse D, Sterz F, Lozano M, Brouwer MA, Westfall M, Souders CM, Travis DT, Herken UR, Lerner EB (2016)
Why do some studies find that CPR fraction is not a predictor of survival?
Resuscitation, 104, 59-62
DOI 10.1016/j.resuscitation.2016.04.013, PubMed 27155547

Publications 2015

González-Otero DM, Ruiz de Gauna S, Ruiz J, Daya MR, Wik L, Russell JK, Kramer-Johansen J, Eftestøl T, Alonso E, Ayala U (2015)
Chest compression rate feedback based on transthoracic impedance
Resuscitation, 93, 82-8
DOI 10.1016/j.resuscitation.2015.05.027, PubMed 26051811

Olsen JA, Brunborg C, Steinberg M, Persse D, Sterz F, Lozano M, Westfall M, Travis DT, Lerner EB, Brouwer MA, Wik L (2015)
Pre-shock chest compression pause effects on termination of ventricular fibrillation/tachycardia and return of organized rhythm within mechanical and manual cardiopulmonary resuscitation
Resuscitation, 93, 158-63
DOI 10.1016/j.resuscitation.2015.04.023, PubMed 25933511

Wik L, Rubertsson S (2015)
Automatic mechanical chest compressions during cardiopulmonary resuscitation: What is the evidence for its use?
Resuscitation, 94, e1
DOI 10.1016/j.resuscitation.2015.06.014, PubMed 26100939

Publications 2014

Hardeland C, Olasveengen TM, Lawrence R, Garrison D, Lorem T, Farstad G, Wik L (2014)
Comparison of Medical Priority Dispatch (MPD) and Criteria Based Dispatch (CBD) relating to cardiac arrest calls
Resuscitation, 85 (5), 612-6
DOI 10.1016/j.resuscitation.2014.01.029, PubMed 24525117

Steinberg MT, Olsen JA, Brunborg C, Persse D, Sterz F, Lozano M, Brouwer MA, Westfall M, Souders CM, van Grunsven PM, Travis DT, Lerner EB, Wik L (2014)
Minimizing pre-shock chest compression pauses in a cardiopulmonary resuscitation cycle by performing an earlier rhythm analysis
Resuscitation, 87, 33-7
DOI 10.1016/j.resuscitation.2014.11.012, PubMed 25461493

Wik L, Olsen JA, Persse D, Sterz F, Lozano M, Brouwer MA, Westfall M, Souders CM, Malzer R, van Grunsven PM, Travis DT, Whitehead A, Herken UR, Lerner EB (2014)
Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest. The randomized CIRC trial
Resuscitation, 85 (6), 741-8
DOI 10.1016/j.resuscitation.2014.03.005, PubMed 24642406

Wik L, Olsen JA, Persse D, Sterz F, Lozano M, Brouwer MA, Westfall M, Souders CM, Malzer R, van Grunsven PM, Travis DT, Whitehead A, Herken UR, Lerner EB (2014)
Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest. The randomized CIRC trial (vol 85, pg 741, 2014)
Resuscitation, 85 (9), 1306
DOI 10.1016/j.resuscitation.2014.06.017

Publications 2013

Neset A, Nordseth T, Kramer-Johansen J, Wik L, Olasveengen TM (2013)
Effects of adrenaline on rhythm transitions in out-of-hospital cardiac arrest
Acta Anaesthesiol Scand, 57 (10), 1260-7
DOI 10.1111/aas.12184, PubMed 24032427

Publications 2012

Nordseth T, Olasveengen TM, Kvaløy JT, Wik L, Steen PA, Skogvoll E (2012)
Dynamic effects of adrenaline (epinephrine) in out-of-hospital cardiac arrest with initial pulseless electrical activity (PEA)
Resuscitation, 83 (8), 946-52
DOI 10.1016/j.resuscitation.2012.02.031, PubMed 22429969

Publications 2011

Olasveengen TM, Wik L, Sunde K, Steen PA (2011)
Outcome when adrenaline (epinephrine) was actually given vs. not given - post hoc analysis of a randomized clinical trial
Resuscitation, 83 (3), 327-32
DOI 10.1016/j.resuscitation.2011.11.011, PubMed 22115931

Publications 2010

Kramer-Johansen J, Pytte M, Tomlinson AE, Sunde K, Dorph E, Svendsen JV, Eriksen M, Strømme TA, Wik L (2010)
Mechanical chest compressions with trapezoidal waveform improve haemodynamics during cardiac arrest
Resuscitation, 82 (2), 213-8
DOI 10.1016/j.resuscitation.2010.10.009, PubMed 21093141

Lerner EB, Persse D, Souders CM, Sterz F, Malzer R, Lozano M, Westfall M, Brouwer MA, van Grunsven PM, Whitehead A, Olsen JA, Herken UR, Wik L (2010)
Design of the Circulation Improving Resuscitation Care (CIRC) Trial: a new state of the art design for out-of-hospital cardiac arrest research
Resuscitation, 82 (3), 294-9
DOI 10.1016/j.resuscitation.2010.11.013, PubMed 21196070

Lund-Kordahl I, Olasveengen TM, Lorem T, Samdal M, Wik L, Sunde K (2010)
Improving outcome after out-of-hospital cardiac arrest by strengthening weak links of the local Chain of Survival; quality of advanced life support and post-resuscitation care
Resuscitation, 81 (4), 422-6
DOI 10.1016/j.resuscitation.2009.12.020, PubMed 20122786

Tømte Ø, Sjaastad I, Wik L, Kuzovlev A, Eriksen M, Norseng PA, Sunde K (2010)
Discriminating the effect of accelerated compression from accelerated decompression during high-impulse CPR in a porcine model of cardiac arrest
Resuscitation, 81 (4), 488-92
DOI 10.1016/j.resuscitation.2009.12.028, PubMed 20122780

Publications 2009

Lorem T, Steen PA, Wik L (2009)
High school students as ambassadors of CPR--a model for reaching the most appropriate target population?
Resuscitation, 81 (1), 78-81
DOI 10.1016/j.resuscitation.2009.09.030, PubMed 19913984

Olasveengen TM, Eftestøl T, Gundersen K, Wik L, Sunde K (2009)
Acute ischemic heart disease alters ventricular fibrillation waveform characteristics in out-of hospital cardiac arrest
Resuscitation, 80 (4), 412-7
DOI 10.1016/j.resuscitation.2009.01.012, PubMed 19217199

Olasveengen TM, Sunde K, Brunborg C, Thowsen J, Steen PA, Wik L (2009)
Intravenous drug administration during out-of-hospital cardiac arrest: a randomized trial
JAMA, 302 (20), 2222-9
DOI 10.1001/jama.2009.1729, PubMed 19934423

Tomte O, Sunde K, Lorem T, Auestad B, Souders C, Jensen J, Wik L (2009)
Advanced life support performance with manual and mechanical chest compressions in a randomized, multicentre manikin study
Resuscitation, 80 (10), 1152-7
DOI 10.1016/j.resuscitation.2009.07.001, PubMed 19665833

Publications 2008

Lorem T, Palm A, Wik L (2008)
Impact of a self-instruction CPR kit on 7th graders' and adults' skills and CPR performance
Resuscitation, 79 (1), 103-8
DOI 10.1016/j.resuscitation.2008.04.030, PubMed 18656297

Olasveengen TM, Samdal M, Steen PA, Wik L, Sunde K (2008)
Progressing from initial non-shockable rhythms to a shockable rhythm is associated with improved outcome after out-of-hospital cardiac arrest
Resuscitation, 80 (1), 24-9
DOI 10.1016/j.resuscitation.2008.09.003, PubMed 19081664

Olasveengen TM, Steen P, Wik L (2008)
Comprehensive evaluation for quality of prehospital CPR - Reply
Resuscitation, 78 (1), 99
DOI 10.1016/j.resuscitation.2007.12.002

Stecher FS, Olsen JA, Stickney RE, Wik L (2008)
Transthoracic impedance used to evaluate performance of cardiopulmonary resuscitation during out of hospital cardiac arrest
Resuscitation, 79 (3), 432-7
DOI 10.1016/j.resuscitation.2008.08.007, PubMed 19061785

Publications 2007

Bollig G, Steen PA, Wik L (2007)
Standard versus over-the-head cardiopulmonary resuscitation during simulated advanced life support
Prehosp Emerg Care, 11 (4), 443-7
DOI 10.1080/00207450701537050, PubMed 17907030

Grogaard HK, Wik L, Eriksen M, Brekke M, Sunde K (2007)
Continuous mechanical chest compressions during cardiac arrest to facilitate restoration of coronary circulation with percutaneous coronary intervention
J Am Coll Cardiol, 50 (11), 1093-4
DOI 10.1016/j.jacc.2007.05.028, PubMed 17825721

Kramer-Johansen J, Edelson DP, Abella BS, Becker LB, Wik L, Steen PA (2007)
Pauses in chest compression and inappropriate shocks: a comparison of manual and semi-automatic defibrillation attempts
Resuscitation, 73 (2), 212-20
DOI 10.1016/j.resuscitation.2006.09.006, PubMed 17241734

Olasveengen TM, Tomlinson AE, Wik L, Sunde K, Steen PA, Myklebust H, Kramer-Johansen J (2007)
A failed attempt to improve quality of out-of-hospital CPR through performance evaluation
Prehosp Emerg Care, 11 (4), 427-33
DOI 10.1080/10903120701536628, PubMed 17907028

Olasveengen TM, Wik L, Kramer-Johansen J, Sunde K, Pytte M, Steen PA (2007)
Is CPR quality improving? A retrospective study of out-of-hospital cardiac arrest
Resuscitation, 75 (2), 260-6
DOI 10.1016/j.resuscitation.2007.04.016, PubMed 17560005

Olasveengen TM, Wik L, Steen PA (2007)
Quality of cardiopulmonary resuscitation before and during transport in out-of-hospital cardiac arrest
Resuscitation, 76 (2), 185-90
DOI 10.1016/j.resuscitation.2007.07.001, PubMed 17728039

Pytte M, Dorph E, Sunde K, Kramer-Johansen J, Wik L, Steen PA (2007)
Arterial blood gases during basic life support of human cardiac arrest victims
Resuscitation, 77 (1), 35-8
DOI 10.1016/j.resuscitation.2007.10.005, PubMed 18035475

Ødegaard S, Kramer-Johansen J, Bromley A, Myklebust H, Nysaether J, Wik L, Steen PA (2007)
Chest compressions by ambulance personnel on chests with variable stiffness: abilities and attitudes
Resuscitation, 74 (1), 127-34
DOI 10.1016/j.resuscitation.2006.12.006, PubMed 17368692

Publications 2006

Bollig G, Løvhaug SW, Sagen Ø, Svendsen MV, Steen PA, Wik L (2006)
Airway management by paramedics using endotracheal intubation with a laryngoscope versus the oesophageal tracheal Combitube and EasyTube on manikins: a randomised experimental trial
Resuscitation, 71 (1), 107-11
DOI 10.1016/j.resuscitation.2006.02.016, PubMed 16942827

Edelson DP, Abella BS, Kramer-Johansen J, Wik L, Myklebust H, Barry AM, Merchant RM, Hoek TL, Steen PA, Becker LB (2006)
Effects of compression depth and pre-shock pauses predict defibrillation failure during cardiac arrest
Resuscitation, 71 (2), 137-45
DOI 10.1016/j.resuscitation.2006.04.008, PubMed 16982127

Kramer-Johansen J, Myklebust H, Wik L, Fellows B, Svensson L, Sørebø H, Steen PA (2006)
Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study
Resuscitation, 71 (3), 283-92
DOI 10.1016/j.resuscitation.2006.05.011, PubMed 17070980

Kramer-Johansen J, Sunde K, Pytte M, Wik L, Steen PA (2006)
Reconfirmation algorithms should be the standard of care in automated external defibrillators
Resuscitation, 70 (3), 474-5; author reply 475
DOI 10.1016/j.resuscitation.2006.04.010, PubMed 16875772

Odegaard S, Saether E, Steen PA, Wik L (2006)
Quality of lay person CPR performance with compression: ventilation ratios 15:2, 30:2 or continuous chest compressions without ventilations on manikins
Resuscitation, 71 (3), 335-40
DOI 10.1016/j.resuscitation.2006.05.012, PubMed 17069958

Pytte M, Kramer-Johansen J, Eilevstjønn J, Eriksen M, Strømme TA, Godang K, Wik L, Steen PA, Sunde K (2006)
Haemodynamic effects of adrenaline (epinephrine) depend on chest compression quality during cardiopulmonary resuscitation in pigs
Resuscitation, 71 (3), 369-78
DOI 10.1016/j.resuscitation.2006.05.003, PubMed 17023108

Publications 2005

Eftestøl T, Losert H, Kramer-Johansen J, Wik L, Sterz F, Steen PA (2005)
Independent evaluation of a defibrillation outcome predictor for out-of-hospital cardiac arrested patients
Resuscitation, 67 (1), 55-61
DOI 10.1016/j.resuscitation.2005.05.006, PubMed 16154680

Kramer-Johansen J, Wik L, Steen PA (2005)
Advanced cardiac life support before and after tracheal intubation--direct measurements of quality
Resuscitation, 68 (1), 61-9
DOI 10.1016/j.resuscitation.2005.05.020, PubMed 16325329

Vatsgar TT, Ingebrigtsen O, Fjose LO, Wikstrøm B, Nilsen JE, Wik L (2005)
Cardiac arrest and resuscitation with an automatic mechanical chest compression device (LUCAS) due to anaphylaxis of a woman receiving caesarean section because of pre-eclampsia
Resuscitation, 68 (1), 155-9
DOI 10.1016/j.resuscitation.2005.06.001, PubMed 16221521

Wik L, Kiil S (2005)
Use of an automatic mechanical chest compression device (LUCAS) as a bridge to establishing cardiopulmonary bypass for a patient with hypothermic cardiac arrest
Resuscitation, 66 (3), 391-4
DOI 10.1016/j.resuscitation.2005.03.011, PubMed 15992987

Wik L, Kramer-Johansen J, Myklebust H, Sørebø H, Svensson L, Fellows B, Steen PA (2005)
Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest
JAMA, 293 (3), 299-304
DOI 10.1001/jama.293.3.299, PubMed 15657322

Wik L, Myklebust H, Auestad BH, Steen PA (2005)
Twelve-month retention of CPR skills with automatic correcting verbal feedback
Resuscitation, 66 (1), 27-30
DOI 10.1016/j.resuscitation.2004.12.022, PubMed 15993726

Publications 2004

Eftestøl T, Wik L, Sunde K, Steen PA (2004)
Effects of cardiopulmonary resuscitation on predictors of ventricular fibrillation defibrillation success during out-of-hospital cardiac arrest
Circulation, 110 (1), 10-5
DOI 10.1161/01.CIR.0000133323.15565.75, PubMed 15210599

Wik L, Hansen TB, Kjensli K, Steen PA (2004)
Rapid extrication from a car wreck
Injury, 35 (8), 739-45
DOI 10.1016/j.injury.2004.01.003, PubMed 15246795

Publications 2003

Wik L (2003)
Rediscovering the importance of chest compressions to improve the outcome from cardiac arrest
Resuscitation, 58 (3), 267-9
DOI 10.1016/s0300-9572(03)00267-3, PubMed 12969601

Wik L, Dorph E, Auestad B, Andreas Steen P (2003)
Evaluation of a defibrillator-basic cardiopulmonary resuscitation programme for non medical personnel
Resuscitation, 56 (2), 167-72
DOI 10.1016/s0300-9572(02)00351-9, PubMed 12589990

Wik L, Hansen TB, Fylling F, Steen T, Vaagenes P, Auestad BH, Steen PA (2003)
Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out-of-hospital ventricular fibrillation: a randomized trial
JAMA, 289 (11), 1389-95
DOI 10.1001/jama.289.11.1389, PubMed 12636461

Aasheim A, Bendz B, Naess AC, Steen PA, Wik L, Mangschau A (2003)
[Prehospital ECG reduces time to treatment with percutaneous coronary interventions]
Tidsskr Nor Laegeforen, 123 (10), 1353-4
PubMed 12806676

Publications 2002

Langhelle A, Strømme T, Sunde K, Wik L, Nicolaysen G, Steen PA (2002)
Inspiratory impedance threshold valve during CPR
Resuscitation, 52 (1), 39-48
DOI 10.1016/s0300-9572(01)00442-7, PubMed 11801347

Wik L, Myklebust H, Auestad BH, Steen PA (2002)
Retention of basic life support skills 6 months after training with an automated voice advisory manikin system without instructor involvement
Resuscitation, 52 (3), 273-9
DOI 10.1016/s0300-9572(01)00476-2, PubMed 11886733

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