Light Meets Precision:
EIC Pathfinder Project SCALPEL Pioneering a Revolutionary Photoimmunotherapy for Cancer
Theo Theodossiou, Project coordinator
In a groundbreaking effort to revolutionise modern oncology, the SCALPEL project launches a Europe wide initiative aimed at redefining cancer treatment by using light to precisely ‘click’ tags to cancer cells, enabling the immune system to recognise and destroy them with unparalleled accuracy. Project coordinator is Theo Theodossiou, head of the Protonics project group at the Department of Radiation Biology at OUH.
The multidisciplinary initiative funded by the European Innovation Council Pathfinder programme under Horizon Europe with a total budget of more than EUR 4 million aims to revolutionise modern oncology offering new hope for millions worldwide.
Amstutz A, Schandelmaier S, Ewald H, Speich B, Schwenke JM, Schönenberger CM, Schobinger S, Agoritsas T, Tomashek KM, Nayak S, Makowski M, Morales-Ortega A, Bernal-Bello D, Pomponio G, Ferrarini A, Ghazaeian M, Hall F, Bond S, García-Morales MT, Jiménez-González M, Arribas JR, Guimaraães PO, Tavares CAM, Berwanger O, Yazdanpanah Yet al.(2025) Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials Lancet Respir Med(in press) DOI 10.1016/S2213-2600(25)00055-4, PubMed 40378861
Miller A, Symington F, Garner P, Pedersen M(2025) Patients with severe ME/CFS need hope and expert multidisciplinary care BMJ, 389, r977 DOI 10.1136/bmj.r977, PubMed 40368436