New book on RNA Interference edited by Mouldy Sioud recently published
Mouldy Sioud from Department of Immunology at the Institute for Cancer Research is the editor of a new book published November 10th entitled "RNA Interference: Challenges and Therapeutic Opportunities". The book is included in the series "Methods in Molecular Biology, Vol. 1218" and provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA's unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes.
These excellent chapters will assist researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies.
Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.
Includes cutting-edge techniques in using RNA interference for therapeutic purposes
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
Published in Level 2 journals, first or last author from Oslo University Hospital.
Kristensen AMD, Munkhaugen J, Halvorsen S, Olsen MH, Bakken A, Sehested TSG, Ruddox V, Lange T, Fagerland MW, Torp-Pedersen C, Prescott E, Atar D(2023) The Danish-Norwegian randomized trial on beta-blocker therapy after myocardial infarction: Design, rationale, and baseline characteristics Eur Heart J Cardiovasc Pharmacother(in press) DOI 10.1093/ehjcvp/pvad093, PubMed 38017624
Nordahl-Hansen A, Cogo-Moreira H, Panjeh S, Quintana DS(2023) Redefining effect size interpretations for psychotherapy RCTs in depression J Psychiatr Res, 169, 38-41(in press) DOI 10.1016/j.jpsychires.2023.11.009, PubMed 38000182
Lekva T, Sundaram AYF, Roland MCP, Åsheim J, Michelsen AE, Norwitz ER, Aukrust P, Gilfillan GD, Ueland T(2023) Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia-an exploratory study BMC Med, 21(1), 458 DOI 10.1186/s12916-023-03178-x, PubMed 37996819