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Madeleine Fosslie, researcher in the Genome and Epigenome Regulation in Embryo Development, Ageing and Disease group at the Department of Microbiology, and Erkut Ilaslan, researcher at University of Copenhagen, are first authors on this Nature Communications paper. This study sheds light on the fundamental biology of how the genome is restructured and reprogrammed during the transition from egg to early embryo.
This study examines how DNA is organized and regulated in mouse egg cells and very early embryos by following a protein called H2A.Z, one of the proteins around which DNA is wrapped inside the cell. 

Emma Lång, member of the "Cell and tissue dynamics research group" at the Department of Microbiology, has received 9 million NOK in funding from Helse Sør-Øst RHF for her project "Navigating the Tunnel: Keratinocyte Dynamics & Therapeutic Targeting of IL-17 in Hidradenitis Suppurativa".

This interdisciplinary study aims to uncover the underlying cellular mechanisms of the chronic inflammatory skin disease, Hidradenitis Suppurativa (HS). HS is a debilitating disease that severely impacts patients’ quality of life, with current treatments being insufficient and late diagnosis complicating care.

Lorena Arranz, leader of the Stem Cells, Ageing and Cancer research group at the Department of Microbiology and Deputy Centre Director of CRESCO, has received 9 million NOK in funding from Helse Sør-Øst RHF for her project NEUROTARGET: The nervous system as a druggable vulnerability in myeloid blood cancers.

Helse Sør-Øst RHF has awarded regional research funding to 96 research projects starting in 2026. The projects cover a wide range of disciplines and aim to contribute new knowledge and improved patient care. Lorena Arranz received funding from the thematic open structure, available to all research areas in the specialist healthcare services.

A research team led by Arne Søraas at Oslo University Hospital is competing for more than one billion NOK in an international XPRIZE contest to demonstrate that treatment with young blood plasma can slow the aging processes. The project’s primary aim is to investigate whether plasma from young donors can stabilize or reduce cognitive decline in patients with early Alzheimer’s disease. The idea may sound like science fiction, but it builds on longstanding animal experiments in which socalled parabiosis showed that blood from young animals can produce measurable improvements in the brain function of older animals.

Yanjiao Li, researcher form the Department of Microbiology at Oslo University Hospital and CRESCO Centre for embryology and healthy development (UiO), has received 10 million Norwegian kroner in FRIPRO funding from the Research Council of Norway. FRIPRO is awarded for frontier research with the potential to push the boundaries of knowledge.
One in six people experiences infertility. Assisted reproductive technologies (ARTs)-babies now account for 6% of all newborns. Although in vitro fertilization (IVF) helps many, it still fails often. Only about half of the fertilized eggs grow into blastocysts, the stage where they are implanted in the uterus. Not every transferred embryo results in pregnancy.

In order to stimulate excellent research and draw attention to the hospital's research activity, Oslo University Hospital rewards outstanding publications twice a year. Six research groups were awarded for their excellent papers published the first half-year of 2025 during a ceremony on December 3rd. Each group received NOK 50.000 earmarked for further research, and the prize winners gave short presentations of their findings.

The awards for outstanding research articles are distributed twice a year based on more than 2,400 scientific articles published annually by OUS. The division's research committees nominate the articles and an external committee evaluates and finally selects the six worthy winners.

One in six couples worldwide struggle with infertility, and the number is rising. In Norway, the fertility rate has fallen by almost 30% in the past decade, and 6% of children are now born through assisted reproductive technology (ART).  Yanjiao Li, researcher at Oslo University Hospital and Centre for Embryology and Healthy Development (CRESCO), has written a blog post for the Oslo University Hospital blog OUS Insight. 

Mari Kaarbø, leader of the Virology Research Group at Oslo University Hospital, was interviewed by the journal Bioingeniøren after leading one of the research teams that collaborated on the “Oslo patient” project. Kaarbø has been primarily responsible for the careful examination of the patient’s blood and gut cells to identify HIV reservoirs. The patient has been off treatment and clinically virus‑free for nearly three years.