Publications

Publications 2025

Bäcker N, Ast J, Martorana D, Renicke C, Berger J, Mais CN, Christ M, Stehlik T, Heimerl T, Wernet V, Taxis C, Pané-Farré J, Bölker M, Klatt JM, Sandrock B, Schink KO, Bange G, Freitag J (2025)
Peroxisomal core structures segregate diverse metabolic pathways
Nat Commun, 16 (1), 1802
DOI 10.1038/s41467-025-57053-9, PubMed 39979331
Dillard C, Teles-Reis J, Jain A, Antunes MG, Ruiz-Duran P, Qi Y, Le Borgne R, Jasper H, Rusten TE (2025)
NF-κB signaling driven by oncogenic Ras contributes to tumorigenesis in a Drosophila carcinoma model
PLoS Biol, 23 (4), e3002663
DOI 10.1371/journal.pbio.3002663, PubMed 40294135
Kaur N, Carlsson SR, Lystad AH (2025)
Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms
Front Cell Dev Biol, 13, 1559125
DOI 10.3389/fcell.2025.1559125, PubMed 40213394
Kolapalli SP, Beese CJ, Reid SE, Brynjólfsdóttir SH, Jørgensen MH, Jain A, Cuenco J, Lewinska M, Abdul-Al A, López AR, Jäättelä M, Sakamoto K, Andersen JB, Maeda K, Rusten TE, Lund AH, Frankel LB (2025)
Pellino 3 E3 ligase promotes starvation-induced autophagy to prevent hepatic steatosis
Sci Adv, 11 (3), eadr2450
DOI 10.1126/sciadv.adr2450, PubMed 39823344
Kondo T, Bourassa FXP, Achar S, DuSold J, Céspedes PF, Ando M, Dwivedi A, Moraly J, Chien C, Majdoul S, Kenet AL, Wahlsten M, Kvalvaag A, Jenkins E, Kim SP, Ade CM, Yu Z, Gaud G, Davila M, Love P, Yang JC, Dustin ML, Altan-Bonnet G, François P, Taylor N (2025)
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
Cell, 188 (9), 2372-2389.e35
DOI 10.1016/j.cell.2025.03.017, PubMed 40220754
Medhus A, Schink KO, Longva AS, Engebraaten O, Berg K, Weyergang A (2025)
The mechanisms of HER2 targeted ADCs are dependent on Rab GTPases
Ther Adv Med Oncol, 17, 17588359251332473
DOI 10.1177/17588359251332473, PubMed 40297622
Mlynska A, Dobrovolskiene N, Suveizde K, Lukaseviciute G, Sagini K, Gracia BM, Romero S, Llorente A, Line A, Butkute A, Gudaite B, Venckunas T, Matuseviciene N, Pasukoniene V (2025)
Exercise-induced extracellular vesicles delay tumor development by igniting inflammation in an immunologically cold triple-negative breast cancer mouse model
J Sport Health Sci, 101041 (in press)
DOI 10.1016/j.jshs.2025.101041, PubMed 40250619
Nita A, Abraham SP, Elrefaay ER, Fafilek B, Cizkova E, Ursachi VC, Gudernova I, Koudelka A, Dudeja P, Gregor T, Feketova Z, Rico G, Svozilova K, Celiker C, Czyrek AA, Barta T, Trantirek L, Wiedlocha A, Krejci P, Bosakova M (2025)
FGFR2 residence in primary cilia is necessary for epithelial cell signaling
J Cell Biol, 224 (7)
DOI 10.1083/jcb.202311030, PubMed 40257378
Puurand M, Llorente A, Linē A, Kaambre T (2025)
Exercise-induced extracellular vesicles in reprogramming energy metabolism in cancer
Front Oncol, 14, 1480074
DOI 10.3389/fonc.2024.1480074, PubMed 39834935
Skotland T, Ekroos K, Llorente A, Sandvig K (2025)
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
J Extracell Vesicles, 14 (3), e70049
DOI 10.1002/jev2.70049, PubMed 40091364
Trachsel-Moncho L, Mathai BJ, Veroni C, Simonsen A (2025)
SNX10 at the crossroad of endocytosis and piecemeal mitophagy
Autophagy, 1-3 (in press)
DOI 10.1080/15548627.2025.2499641, PubMed 40327657
Trachsel-Moncho L, Veroni C, Mathai BJ, Lapao A, Singh S, Asp NT, Schultz SW, Pankiv S, Simonsen A (2025)
SNX10 functions as a modulator of piecemeal mitophagy and mitochondrial bioenergetics
J Cell Biol, 224 (5)
DOI 10.1083/jcb.202404009, PubMed 40052924
Tunset ME, Haslene-Hox H, Larsen JB, Kondziella D, Nygård M, Pedersen SA, Vaaler A, Llorente A (2025)
Clinical studies of blood-borne Extracellular vesicles in psychiatry: A systematic review
J Psychiatr Res, 182, 373-390
DOI 10.1016/j.jpsychires.2025.01.037, PubMed 39862765
Zhen Y, Stenmark H (2025)
Sustained release of cytokines from migrasomes
Extracell Vesicles Circ Nucl Acids, 6 (1), 171-175
DOI 10.20517/evcna.2025.15, PubMed 40206805

Publications 2024

Brugger M, Lauri A, Zhen Y, Gramegna LL, Zott B, Sekulić N, Fasano G, Kopajtich R, Cordeddu V, Radio FC, Mancini C, Pizzi S, Paradisi G, Zanni G, Vasco G, Carrozzo R, Palombo F, Tonon C, Lodi R, La Morgia C, Arelin M, Blechschmidt C, Finck T, Sørensen V, Kreiser K et al. (2024)
Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy
Am J Hum Genet, 111 (3), 594-613
DOI 10.1016/j.ajhg.2024.02.005, PubMed 38423010
Casey NP, Kleinmanns K, Forcados C, Gelebart PF, Joaquina S, Lode M, Benard E, Kaveh F, Caulier B, Helgestad Gjerde C, García de Jalón E, Warren DJ, Lindemann K, Rokkones E, Davidson B, Myhre MR, Kvalheim G, Bjørge L, McCormack E, Inderberg EM, Wälchli S (2024)
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
J Immunother Cancer, 12 (4)
DOI 10.1136/jitc-2023-008179, PubMed 38604812
Caulier B, Joaquina S, Gelebart P, Dowling TH, Kaveh F, Thomas M, Tandaric L, Wernhoff P, Katyayini NU, Wogsland C, Gjerstad ME, Fløisand Y, Kvalheim G, Marr C, Kobold S, Enserink JM, Gjertsen BT, McCormack E, Inderberg EM, Wälchli S (2024)
CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
Cell Rep Med, 5 (6), 101572
DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420
Corrales J, Ramos-Alonso L, González-Sabín J, Ríos-Lombardía N, Trevijano-Contador N, Engen Berg H, Sved Skottvoll F, Moris F, Zaragoza O, Chymkowitch P, Garcia I, Enserink JM (2024)
Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
Microbiol Spectr, 12 (2), e0259423
DOI 10.1128/spectrum.02594-23, PubMed 38230926
Duran J, Salinas JE, Wheaton RP, Poolsup S, Allers L, Rosas-Lemus M, Chen L, Cheng Q, Pu J, Salemi M, Phinney B, Ivanov P, Lystad AH, Bhaskar K, Rajaiya J, Perkins DJ, Jia J (2024)
Calcium signaling from damaged lysosomes induces cytoprotective stress granules
EMBO J, 43 (24), 6410-6443
DOI 10.1038/s44318-024-00292-1, PubMed 39533058
Fuentes-Martín R, Ayuda-Durán P, Hanes R, Gallego-Yerga L, Wolterinck L, Enserink JM, Álvarez R, Peláez R (2024)
Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents
Eur J Med Chem, 275, 116617
DOI 10.1016/j.ejmech.2024.116617, PubMed 38959729
Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, Pinto-Fernández A, Draganov SD, Vendrell I, Liu G, Yao X, Kvalvaag A, Dominey-Foy DCC, Nanayakkara C, Kanellakis N, Chen YL et al. (2024)
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
Nat Immunol, 25 (5), 834-846
DOI 10.1038/s41590-024-01802-3, PubMed 38561495
Klavina A, Ceseiko R, Campa M, Jermolenko GF, Eglitis K, Llorente A, Linē A (2024)
The Effect of High-Intensity Interval Training on Quality of Life and Incidence of Chemotherapy Side Effects in Women With Breast Cancer
Integr Cancer Ther, 23, 15347354241297385
DOI 10.1177/15347354241297385, PubMed 39548802
Kvalvaag A, Dustin ML (2024)
Clathrin controls bidirectional communication between T cells and antigen presenting cells
Bioessays, 46 (4), e2300230
DOI 10.1002/bies.202300230, PubMed 38412391
Lamsal A, Andersen SB, Johansson I, Desgarnier MD, Wolowczyk C, Engedal N, Vietri M, Bjørkøy G, Giambelluca MS, Pettersen K (2024)
Elucidating the power of arginine restriction: taming type I interferon response in breast cancer via selective autophagy
Cell Commun Signal, 22 (1), 481
DOI 10.1186/s12964-024-01858-6, PubMed 39380098
Llorente A, Brokāne A, Mlynska A, Puurand M, Sagini K, Folkmane S, Hjorth M, Martin-Gracia B, Romero S, Skorinkina D, Čampa M, Cešeiko R, Romanchikova N, Kļaviņa A, Käämbre T, Linē A (2024)
From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
J Extracell Vesicles, 13 (8), e12500
DOI 10.1002/jev2.12500, PubMed 39183543
Nähse V, Stenmark H, Schink KO (2024)
Omegasomes control formation, expansion, and closure of autophagosomes
Bioessays, 46 (6), e2400038
DOI 10.1002/bies.202400038, PubMed 38724256
Pankiv S, Dahl AK, Aas A, Andersen RL, Brech A, Holland P, Singh S, Bindesbøll C, Simonsen A (2024)
BEACH domain proteins function as cargo-sorting adaptors in secretory and endocytic pathways
J Cell Biol, 223 (12)
DOI 10.1083/jcb.202408173, PubMed 39514288
Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, Littman DR, Dustin ML, Wang J, Kong XP (2024)
Transmembrane domain-driven PD-1 dimers mediate T cell inhibition
Sci Immunol, 9 (93), eade6256
DOI 10.1126/sciimmunol.ade6256, PubMed 38457513
Radulovic M, Stenmark H (2024)
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545
Rosselle L, Leray T, Joaquina S, Caulier B, McCormack E, Gelebart P, Wälchli S, Inderberg EM (2024)
Protocol for production of tonic CAR T cells with dasatinib
STAR Protoc, 6 (1), 103529
DOI 10.1016/j.xpro.2024.103529, PubMed 39739533
Sandvig K, Iversen TG, Skotland T (2024)
Entry of nanoparticles into cells and tissues: status and challenges
Beilstein J Nanotechnol, 15, 1017-1029
DOI 10.3762/bjnano.15.83, PubMed 39161463
Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K (2024)
Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
Nat Rev Mol Cell Biol, 25 (10), 759-760
DOI 10.1038/s41580-024-00758-4, PubMed 38951702
Theriot JA, Simonsen A, Tolić I, Leonetti MD, Mayor S, Bassereau P, Paluch EK, Han J, Covert MW, Mizushima N, Reck-Peterson S, Strasser A, Cheeseman I (2024)
Cell biology is…
Cell, 187 (2), 219-224
DOI 10.1016/j.cell.2023.12.020, PubMed 38242078
Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E (2024)
The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
Cell Mol Life Sci, 81 (1), 171
DOI 10.1007/s00018-024-05165-8, PubMed 38597989
Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Int J Nanomedicine, 19, 3009-3029
DOI 10.2147/IJN.S450283, PubMed 38562610
Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H et al. (2024)
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
J Gerontol A Biol Sci Med Sci, 79 (4)
DOI 10.1093/gerona/glae029, PubMed 38289789
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S et al. (2024)
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
J Extracell Vesicles, 13 (2), e12404
DOI 10.1002/jev2.12404, PubMed 38326288
Wenzel EM, Pedersen NM, Elfmark LA, Wang L, Kjos I, Stang E, Malerød L, Brech A, Stenmark H, Raiborg C (2024)
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434
Wu C, Gunnarsson EB, Myklebust EM, Köhn-Luque A, Tadele DS, Enserink JM, Frigessi A, Foo J, Leder K (2024)
Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
PLoS Comput Biol, 20 (3), e1011888
DOI 10.1371/journal.pcbi.1011888, PubMed 38446830
Zhen Y, Stenmark H (2024)
A dual-purpose fusion complex in autophagy
Cell Res, 34 (3), 183-184
DOI 10.1038/s41422-023-00925-w, PubMed 38228880
Zhen Y, Stenmark H (2024)
Exosome regulation by Rubicon in ageing
Nat Cell Biol, 26 (9), 1380-1381
DOI 10.1038/s41556-024-01482-z, PubMed 39174741

Publications 2023

Al Outa A, Hicks S, Thambawita V, Andresen S, Enserink JM, Halvorsen P, Riegler MA, Knævelsrud H (2023)
CELLULAR, A Cell Autophagy Imaging Dataset
Sci Data, 10 (1), 806
DOI 10.1038/s41597-023-02687-x, PubMed 37973836
Andersen AN, Brodersen AM, Ayuda-Durán P, Piechaczyk L, Tadele DS, Baken L, Fredriksen J, Stoksflod M, Lenartova A, Fløisand Y, Skånland SS, Enserink JM (2023)
Clinical forecasting of acute myeloid leukemia using ex vivo drug-sensitivity profiling
Cell Rep Methods, 3 (12), 100654
DOI 10.1016/j.crmeth.2023.100654, PubMed 38065095
Ayuda-Durán P, Hermansen JU, Giliberto M, Yin Y, Hanes R, Gordon S, Kuusanmäki H, Brodersen AM, Andersen AN, Taskén K, Wennerberg K, Enserink JM, Skånland SS (2023)
Standardized assays to monitor drug sensitivity in hematologic cancers
Cell Death Discov, 9 (1), 435
DOI 10.1038/s41420-023-01722-5, PubMed 38040674
Bajo-Santos C, Brokāne A, Zayakin P, Endzeliņš E, Soboļevska K, Belovs A, Jansons J, Sperga M, Llorente A, Radoviča-Spalviņa I, Lietuvietis V, Linē A (2023)
Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
Front Mol Biosci, 10, 980433
DOI 10.3389/fmolb.2023.980433, PubMed 36818049
Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML (2023)
Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
Biophys J, 123 (15), 2271-2281
DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785
Casey NP, Klee CH, Fåne A, Caulier B, Graczyk-Jarzynka A, Krawczyk M, Fidyt K, Josefsson SE, Köksal H, Dillard P, Patkowska E, Firczuk M, Smeland EB, Winiarska M, Myklebust JH, Inderberg EM, Wälchli S (2023)
Efficient chimeric antigen receptor targeting of a central epitope of CD22
J Biol Chem, 299 (7), 104883
DOI 10.1016/j.jbc.2023.104883, PubMed 37269947
Chen Y, He L, Ianevski A, Ayuda-Durán P, Potdar S, Saarela J, Miettinen JJ, Kytölä S, Miettinen S, Manninen M, Heckman CA, Enserink JM, Wennerberg K, Aittokallio T (2023)
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc, 19 (1), 60-82
DOI 10.1038/s41596-023-00903-x, PubMed 37996540
Clement D, Szabo EK, Krokeide SZ, Wiiger MT, Vincenti M, Palacios D, Chang YT, Grimm C, Patel S, Stenmark H, Brech A, Majhi RK, Malmberg KJ (2023)
The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
J Immunol, 211 (9), 1348-1358
DOI 10.4049/jimmunol.2300406, PubMed 37737664
Davies EM, Mitchell CA, Stenmark HA (2023)
Phosphoinositides in New Spaces
Cold Spring Harb Perspect Biol, 15 (9)
DOI 10.1101/cshperspect.a041406, PubMed 37463718
Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C (2023)
Protrudin-mediated ER-endosome contact sites promote phagocytosis
Cell Mol Life Sci, 80 (8), 216
DOI 10.1007/s00018-023-04862-0, PubMed 37468729
Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
screenwerk: a modular tool for the design and analysis of drug combination screens
Bioinformatics, 39 (1)
DOI 10.1093/bioinformatics/btac840, PubMed 36573326
Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A (2023)
siRNA screening reveals that SNAP29 contributes to exosome release
Cell Mol Life Sci, 80 (7), 177
DOI 10.1007/s00018-023-04822-8, PubMed 37285022
Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
Automated tracking of cell migration in phase contrast images with CellTraxx
Sci Rep, 13 (1), 22982
DOI 10.1038/s41598-023-50227-9, PubMed 38151514
Joaquina S, Forcados C, Caulier B, Inderberg EM, Wälchli S (2023)
Determination of CAR T cell metabolism in an optimized protocol
Front Bioeng Biotechnol, 11, 1207576
DOI 10.3389/fbioe.2023.1207576, PubMed 37409169
Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H (2023)
The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
iScience, 26 (10), 107726
DOI 10.1016/j.isci.2023.107726, PubMed 37720104
Kaur N, Carlsson SR, Lystad AH (2023)
The separate axes of TECPR1 and ATG16L1 in CASM
Autophagy, 20 (1), 214-215
DOI 10.1080/15548627.2023.2255462, PubMed 37676042
Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525
Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
Proc Natl Acad Sci U S A, 120 (6), e2211368120
DOI 10.1073/pnas.2211368120, PubMed 36730202
Köhn-Luque A, Myklebust EM, Tadele DS, Giliberto M, Schmiester L, Noory J, Harivel E, Arsenteva P, Mumenthaler SM, Schjesvold F, Taskén K, Enserink JM, Leder K, Frigessi A, Foo J (2023)
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
Cell Rep Methods, 3 (3), 100417
DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380
Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, Wiedlocha A, Otlewski J, Zakrzewska M (2023)
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
Cell Mol Life Sci, 80 (10), 311
DOI 10.1007/s00018-023-04964-9, PubMed 37783936
Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
Cell Commun Signal, 21 (1), 50
DOI 10.1186/s12964-023-01062-y, PubMed 36882786
Margadant F, Almsherqi Z, Xu X, Deng Y (2023)
Optical Properties and Interference Effects of the Lens Mitochondrion
Membranes (Basel), 13 (6)
DOI 10.3390/membranes13060610, PubMed 37367815
Migliano SM, Schultz SW, Wenzel EM, Takáts S, Liu D, Mørk S, Tan KW, Rusten TE, Raiborg C, Stenmark H (2023)
Removal of hypersignaling endosomes by simaphagy
Autophagy, 20 (4), 769-791
DOI 10.1080/15548627.2023.2267958, PubMed 37840274
Nunzi E, Mezzasoma L, Bellezza I, Zelante T, Orvietani P, Coata G, Giardina I, Sagini K, Manni G, Di Michele A, Gargaro M, Talesa VN, Di Renzo GC, Fallarino F, Romani R (2023)
Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
Int J Mol Sci, 24 (3)
DOI 10.3390/ijms24032527, PubMed 36768851
Nähse V, Raiborg C, Tan KW, Mørk S, Torgersen ML, Wenzel EM, Nager M, Salo VT, Johansen T, Ikonen E, Schink KO, Stenmark H (2023)
ATPase activity of DFCP1 controls selective autophagy
Nat Commun, 14 (1), 4051
DOI 10.1038/s41467-023-39641-9, PubMed 37422481
Nähse V, Schink KO, Stenmark H (2023)
ATPase-regulated autophagosome biogenesis
Autophagy, 20 (1), 218-219
DOI 10.1080/15548627.2023.2255967, PubMed 37722386
Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE (2023)
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Circ Res, 132 (11), e188-e205
DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790
Pust S, Brech A, Wegner CS, Stenmark H, Haglund K (2023)
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
Cell Mol Life Sci, 80 (8), 235
DOI 10.1007/s00018-023-04864-y, PubMed 37523003
Ramos-Alonso L, Holland P, Le Gras S, Zhao X, Jost B, Bjørås M, Barral Y, Enserink JM, Chymkowitch P (2023)
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Proc Natl Acad Sci U S A, 120 (4), e2210593120
DOI 10.1073/pnas.2210593120, PubMed 36656860
Sagini K, Urbanelli L, Buratta S, Emiliani C, Llorente A (2023)
Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
Pharmaceutics, 15 (2)
DOI 10.3390/pharmaceutics15020437, PubMed 36839759
Sandoz PA, Kuhnigk K, Szabo EK, Thunberg S, Erikson E, Sandström N, Verron Q, Brech A, Watzl C, Wagner AK, Alici E, Malmberg KJ, Uhlin M, Önfelt B (2023)
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Nat Commun, 14 (1), 6035
DOI 10.1038/s41467-023-41634-7, PubMed 37758698
Sarmento MJ, Llorente A, Petan T, Khnykin D, Popa I, Nikolac Perkovic M, Konjevod M, Jaganjac M (2023)
The expanding organelle lipidomes: current knowledge and challenges
Cell Mol Life Sci, 80 (8), 237
DOI 10.1007/s00018-023-04889-3, PubMed 37530856
Skotland T, Llorente A, Sandvig K (2023)
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?
Cold Spring Harb Perspect Biol, 15 (8)
DOI 10.1101/cshperspect.a041415, PubMed 37277192
Stonyte V, Mastrangelopoulou M, Timmer R, Lindbergsengen L, Vietri M, Campsteijn C, Grallert B (2023)
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
EMBO Rep, 24 (8), e56100
DOI 10.15252/embr.202256100, PubMed 37291955
Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 115
DOI 10.1038/s41467-022-35624-4, PubMed 36611026
Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 1767
DOI 10.1038/s41467-023-37488-8, PubMed 36997540
Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
Endocytic trafficking of connexins in cancer pathogenesis
Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772
van den Berg CM, Volkov VA, Schnorrenberg S, Huang Z, Stecker KE, Grigoriev I, Gilani S, Frikstad KM, Patzke S, Zimmermann T, Dogterom M, Akhmanova A (2023)
CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
J Cell Biol, 222 (4)
DOI 10.1083/jcb.202208062, PubMed 36752787
van Royen ME, Soekmadji C, Grange C, Webber JP, Tertel T, Droste M, Buescher A, Giebel B, Jenster GW, Llorente A, Blijdorp CJ, Burger D, Erdbrügger U, Martens-Uzunova ES (2023)
The quick reference card "Storage of urinary EVs" - A practical guideline tool for research and clinical laboratories
J Extracell Vesicles, 12 (3), e12286
DOI 10.1002/jev2.12286, PubMed 36916183
Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
A DnaA-dependent riboswitch for transcription attenuation of the his operon
mLife, 2 (2), 126-140
DOI 10.1002/mlf2.12075, PubMed 38817620
Zhen Y, Stenmark H (2023)
Autophagosome Biogenesis
Cells, 12 (4)
DOI 10.3390/cells12040668, PubMed 36831335
Zhen Y, Stenmark H (2023)
A phosphoinositide kinase triggers migrasome formation
Cell Res, 33 (8), 577-578
DOI 10.1038/s41422-023-00822-2, PubMed 37165066

Publications 2022

Arora A, Kivelä AM, Wang L, Minkeviciene R, Taskinen JH, Zhang B, Koponen A, Sun J, Shirane M, Zhou Y, Hotulainen P, Raiborg C, Olkkonen VM (2022)
Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
Cell Mol Life Sci, 79 (4), 220
DOI 10.1007/s00018-022-04251-z, PubMed 35368213
Blijdorp CJ, Burger D, Llorente A, Martens-Uzunova ES, Erdbrügger U (2022)
Extracellular Vesicles as Novel Players in Kidney Disease
J Am Soc Nephrol, 33 (3), 467-471
DOI 10.1681/ASN.2021091232, PubMed 35131841
Bousquet PA, Manna D, Sandvik JA, Arntzen MØ, Moreno E, Sandvig K, Krengel U (2022)
SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7
Front Immunol, 13, 994790
DOI 10.3389/fimmu.2022.994790, PubMed 36439103
Bril'kov MS, Dobrovolska O, Ødegård-Fougner Ø, Turcu DC, Strømland Ø, Underhaug J, Aasland R, Halskau Ø (2022)
Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix
Front Mol Biosci, 9, 763750
DOI 10.3389/fmolb.2022.763750, PubMed 35495628
Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
Ann N Y Acad Sci, 1510 (1), 79-99
DOI 10.1111/nyas.14745, PubMed 35000205
Charsou C, Ng MYW, Simonsen A (2022)
Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
Autophagy, 19 (7), 2159-2161
DOI 10.1080/15548627.2022.2155020, PubMed 36469687
Doncheva AI, Romero S, Ramirez-Garrastacho M, Lee S, Kolnes KJ, Tangen DS, Olsen T, Drevon CA, Llorente A, Dalen KT, Hjorth M (2022)
Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight
Acta Physiol (Oxf), 236 (4), e13862
DOI 10.1111/apha.13862, PubMed 36377504
Du H, Yang F, Yao C, Lv W, Peng H, Stanciu SG, Stenmark HA, Song YM, Jiang B, Wu A (2022)
"Double-punch" strategy against triple-negative breast cancer via a synergistic therapy of magneto-mechanical force enhancing NIR-II hypothermal ablation
Biomaterials, 291, 121868
DOI 10.1016/j.biomaterials.2022.121868, PubMed 36332286
Du H, Yang F, Yao C, Zhong Z, Jiang P, Stanciu SG, Peng H, Hu J, Jiang B, Li Z, Lv W, Zheng F, Stenmark HA, Wu A (2022)
Multifunctional Modulation of High-Performance Zn_x Fe_3-x O₄ Nanoparticles by Precisely Tuning the Zinc Doping Content
Small, 18 (42), e2201669
DOI 10.1002/smll.202201669, PubMed 36101918
Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
Measuring Autophagic Cargo Flux with Keima-Based Probes
Methods Mol Biol, 2445, 99-115
DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
Enserink JM (2022)
The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?
Bioessays, 44 (7), e2200065
DOI 10.1002/bies.202200065, PubMed 35655365
Enserink JM, Chymkowitch P (2022)
Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
Int J Mol Sci, 23 (3)
DOI 10.3390/ijms23031293, PubMed 35163213
Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q (2022)
Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
Biomedicines, 10 (2)
DOI 10.3390/biomedicines10020232, PubMed 35203441
Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
Br J Cancer, 127 (11), 1939-1953
DOI 10.1038/s41416-022-01973-6, PubMed 36097178
Forcados C, Joaquina S, Casey NP, Caulier B, Wälchli S (2022)
How CAR T Cells Breathe
Cells, 11 (9)
DOI 10.3390/cells11091454, PubMed 35563759
Frikstad KM, Schink KO, Gilani S, Pedersen LB, Patzke S (2022)
3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
Bio Protoc, 12 (6), e4360
DOI 10.21769/BioProtoc.4360, PubMed 35434191
Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
J Control Release, 349, 1
DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
Ganley IG, Simonsen A (2022)
Diversity of mitophagy pathways at a glance
J Cell Sci, 135 (23)
DOI 10.1242/jcs.259748, PubMed 36504076
Garcia-Garcia J, Berge AKM, Overå KS, Larsen KB, Bhujabal Z, Brech A, Abudu YP, Lamark T, Johansen T, Sjøttem E (2022)
TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
FEBS J, 290 (4), 1096-1116
DOI 10.1111/febs.16628, PubMed 36111389
Holland P, Quintana EM, Khezri R, Schoborg TA, Rusten TE (2022)
Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
Sci Rep, 12 (1), 2056
DOI 10.1038/s41598-022-05991-5, PubMed 35136137
Khezri R, Rusten TE (2022)
Autophagy power expands: fuse those cells!
EMBO J, 41 (12), e111424
DOI 10.15252/embj.2022111424, PubMed 35561082
Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M (2022)
Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
Cells, 11 (3)
DOI 10.3390/cells11030522, PubMed 35159330
Lobert VH, Skardal ML, Malerød L, Simensen JE, Algra HA, Andersen AN, Fleischer T, Enserink HA, Liestøl K, Heath JK, Rusten TE, Stenmark HA (2022)
PHLPP1 regulates CFTR activity and lumen expansion through AMPK
Development, 149 (20)
DOI 10.1242/dev.200955, PubMed 35997536
Mateus D, Wiedlocha A (2022)
FGF-FGFR signaling promotes the development of invasive cervical cancer
FEBS J, 289 (12), 3419-3421
DOI 10.1111/febs.16384, PubMed 35146913
Mehto S, Jena KK, Yadav R, Priyadarsini S, Samal P, Krishna S, Dhar K, Jain A, Chauhan NR, Murmu KC, Bal R, Sahu R, Jaiswal P, Sahoo BS, Patnaik S, Kufer TA, Rusten TE, Chauhan S, Prasad P, Chauhan S (2022)
Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection
EMBO J, 41 (23), e111289
DOI 10.15252/embj.2022111289, PubMed 36221902
Mezzasoma L, Bellezza I, Orvietani P, Manni G, Gargaro M, Sagini K, Llorente A, Scarpelli P, Pascucci L, Cellini B, Talesa VN, Fallarino F, Romani R (2022)
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells
FASEB J, 36 (4), e22218
DOI 10.1096/fj.202101657R, PubMed 35218567
Migliano SM, Stenmark H (2022)
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056
Migliano SM, Wenzel EM, Stenmark H (2022)
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
Curr Opin Cell Biol, 75, 102062
DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
GAK and PRKCD kinases regulate basal mitophagy
Autophagy, 18 (2), 467-469
DOI 10.1080/15548627.2021.2015154, PubMed 35001811
Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
Nat Commun, 13 (1), 6283
DOI 10.1038/s41467-022-33933-2, PubMed 36270994
Nissen-Meyer J, Skotland T, Boye E (2022)
Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
EMBO Rep, 23 (3), e54431
DOI 10.15252/embr.202154431, PubMed 35156749
Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828
Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
Front Cell Dev Biol, 10, 1022191
DOI 10.3389/fcell.2022.1022191, PubMed 36619857
Ramos-Alonso L, Garcia I, Enserink JM, Chymkowitch P (2022)
Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
STAR Protoc, 3 (1), 101210
DOI 10.1016/j.xpro.2022.101210, PubMed 35265859
Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G (2022)
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553
Sandvig K, Kavaliauskiene S, Myrann AG, Iversen TG, Skotland T (2022)
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
Toxins (Basel), 14 (5)
DOI 10.3390/toxins14050360, PubMed 35622606
Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
Am J Cancer Res, 12 (1), 327-336
PubMed 35141021
Simonsen A, Wollert T (2022)
Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
Curr Opin Cell Biol, 75, 102064
DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373
Skotland T, Iversen TG, Llorente A, Sandvig K (2022)
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 186, 114326
DOI 10.1016/j.addr.2022.114326, PubMed 35588953
Skotland T, Sandvig K (2022)
Need for more focus on lipid species in studies of biological and model membranes
Prog Lipid Res, 86, 101160
DOI 10.1016/j.plipres.2022.101160, PubMed 35288150
Stanciu SG, Hristu R, Stanciu GA, Tranca DE, Eftimie L, Dumitru A, Costache M, Stenmark HA, Manders H, Cherian A, Tark-Dame M, Manders EMM (2022)
Super-resolution re-scan second harmonic generation microscopy
Proc Natl Acad Sci U S A, 119 (47), e2214662119
DOI 10.1073/pnas.2214662119, PubMed 36375085
Stanciu SG, Tranca DE, Zampini G, Hristu R, Stanciu GA, Chen X, Liu M, Stenmark HA, Latterini L (2022)
Scattering-type Scanning Near-Field Optical Microscopy of Polymer-Coated Gold Nanoparticles
ACS Omega, 7 (13), 11353-11362
DOI 10.1021/acsomega.2c00410, PubMed 35415325
Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
J Cell Sci, 135 (4)
DOI 10.1242/jcs.259138, PubMed 35099014
Wenzel EM, Elfmark LA, Stenmark H, Raiborg C (2022)
ER as master regulator of membrane trafficking and organelle function
J Cell Biol, 221 (10)
DOI 10.1083/jcb.202205135, PubMed 36108241
Wenzel EM, Raiborg C (2022)
ER-endosome contacts master the ins and outs of secretory endosomes
J Cell Biol, 221 (12)
DOI 10.1083/jcb.202210033, PubMed 36355088
Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
Autophagy, 18 (11), 2547-2560
DOI 10.1080/15548627.2022.2039535, PubMed 35220892
Zendrini A, Guerra G, Sagini K, Vagner T, Di Vizio D, Bergese P (2022)
On the surface-to-bulk partition of proteins in extracellular vesicles
Colloids Surf B Biointerfaces, 218, 112728
DOI 10.1016/j.colsurfb.2022.112728, PubMed 35969923
Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
Waves of sumoylation support transcription dynamics during adipocyte differentiation
Nucleic Acids Res, 50 (3), 1351-1369
DOI 10.1093/nar/gkac027, PubMed 35100417

Publications 2021

Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
Wetting regulates autophagy of phase-separated compartments and the cytosol
Nature, 591 (7848), 142-146
DOI 10.1038/s41586-020-2992-3, PubMed 33473217
Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF (2021)
Autophagy in healthy aging and disease
Nat Aging, 1 (8), 634-650
DOI 10.1038/s43587-021-00098-4, PubMed 34901876
Anda S, Boye E, Schink KO, Grallert B (2021)
Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465
Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765
Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
Sci Rep, 11 (1), 4613
DOI 10.1038/s41598-021-84268-9, PubMed 33633289
Caulier B, Enserink JM, Wälchli S (2021)
Pharmacologic Control of CAR T Cells
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094320, PubMed 33919245
Dillard C, Reis JGT, Rusten TE (2021)
Ras^V12; scrib^-/- Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168873, PubMed 34445578
Erdbrügger U, Blijdorp CJ, Bijnsdorp IV, Borràs FE, Burger D, Bussolati B, Byrd JB, Clayton A, Dear JW, Falcón-Pérez JM, Grange C, Hill AF, Holthöfer H, Hoorn EJ, Jenster G, Jimenez CR, Junker K, Klein J, Knepper MA, Koritzinsky EH, Luther JM, Lenassi M, Leivo J, Mertens I, Musante L et al. (2021)
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
J Extracell Vesicles, 10 (7), e12093
DOI 10.1002/jev2.12093, PubMed 34035881
Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Commun Biol, 4 (1), 127
DOI 10.1038/s42003-021-01647-8, PubMed 33514811
Fløisand Y, Schroeder MA, Chevallier P, Selleslag D, Devine S, Renteria AS, Mohty M, Yakoub-Agha I, Chen C, Parfionovas A, Quadri S, Jansson J, Akbari M, Chen YB (2021)
A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
Bone Marrow Transplant, 56 (10), 2477-2488
DOI 10.1038/s41409-021-01356-0, PubMed 34108672
Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T (2021)
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
Autophagy, 17 (12), 4442-4452
DOI 10.1080/15548627.2021.1918915, PubMed 33978540
Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Cell Rep, 37 (13), 110186
DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
Autophagy, 18 (7), 1486-1502
DOI 10.1080/15548627.2021.1988359, PubMed 34740308
Grad I, Hanes R, Ayuda-Durán P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
PLoS One, 16 (3), e0248140
DOI 10.1371/journal.pone.0248140, PubMed 33690666
Guerriero I, Ramberg H, Sagini K, Ramirez-Garrastacho M, Taskén KA, Llorente A (2021)
Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
PLoS One, 16 (6), e0253828
DOI 10.1371/journal.pone.0253828, PubMed 34191854
Holland P, Hagopian WM, Jahren AH, Rusten TE (2021)
Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
BMC Biol, 19 (1), 85
DOI 10.1186/s12915-021-01012-5, PubMed 33966633
Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
Toxins (Basel), 13 (2)
DOI 10.3390/toxins13020102, PubMed 33573355
Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
EMBO J, 40 (18), e107336
DOI 10.15252/embj.2020107336, PubMed 34309071
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751
Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T et al. (2021)
Autophagy in major human diseases
EMBO J, 40 (19), e108863
DOI 10.15252/embj.2021108863, PubMed 34459017
Kosanović M, Llorente A, Glamočlija S, Valdivielso JM, Bozic M (2021)
Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
Int J Mol Sci, 22 (8)
DOI 10.3390/ijms22083887, PubMed 33918699
Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
Biomacromolecules, 22 (10), 4169-4180
DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
Martens-Uzunova ES, Blijdorp CJ, Burger D, Erdbrügger U, Llorente A (2021)
Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead
Eur Urol, 81 (1), 127-128
DOI 10.1016/j.eururo.2021.09.025, PubMed 34625312
Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
Mol Oncol, 16 (5), 1153-1170
DOI 10.1002/1878-0261.13153, PubMed 34861096
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Nat Commun, 12 (1), 6101
DOI 10.1038/s41467-021-26331-7, PubMed 34671015
Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362
Nowosielska EM, Cheda A, Pociegiel M, Cheda L, Szymański P, Wiedlocha A (2021)
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
Int J Mol Sci, 22 (12)
DOI 10.3390/ijms22126309, PubMed 34208396
Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
Nanomaterials (Basel), 11 (5)
DOI 10.3390/nano11051140, PubMed 33924869
Ramirez-Garrastacho M, Bajo-Santos C, Line A, Martens-Uzunova ES, de la Fuente JM, Moros M, Soekmadji C, Tasken KA, Llorente A (2021)
Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
Br J Cancer, 126 (3), 331-350
DOI 10.1038/s41416-021-01610-8, PubMed 34811504
Ramirez-Garrastacho M, Berge V, Linē A, Llorente A (2021)
Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients
Br J Cancer, 126 (3), 492-501
DOI 10.1038/s41416-021-01598-1, PubMed 34811506
Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
J Cell Sci, 134 (3)
DOI 10.1242/jcs.250670, PubMed 33468622
Rudolph MJ, Poon AY, Kavaliauskiene S, Myrann AG, Reynolds-Peterson C, Davis SA, Sandvig K, Vance DJ, Mantis NJ (2021)
Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface
J Mol Biol, 433 (15), 167086
DOI 10.1016/j.jmb.2021.167086, PubMed 34089718
Rønneberg L, Cremaschi A, Hanes R, Enserink JM, Zucknick M (2021)
bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
Brief Bioinform, 22 (6)
DOI 10.1093/bib/bbab251, PubMed 34308471
Sandvig K, Kavaliauskiene S, Skotland T (2021)
The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
Toxins (Basel), 13 (6)
DOI 10.3390/toxins13060377, PubMed 34070659
Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
Nat Commun, 12 (1), 6577
DOI 10.1038/s41467-021-26775-x, PubMed 34772942
Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy, 17 (4), 1046-1048
DOI 10.1080/15548627.2021.1887548, PubMed 33629888
Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909
Siokis A, Robert PA, Demetriou P, Kvalvaag A, Valvo S, Mayya V, Dustin ML, Meyer-Hermann M (2021)
Characterization of mechanisms positioning costimulatory complexes in immune synapses
iScience, 24 (10), 103100
DOI 10.1016/j.isci.2021.103100, PubMed 34622155
Skotland T, Iversen TG, Sandvig K (2021)
Cellular uptake of nanoparticles: Involvement of caveolae?
Precis Nanomed, 4 (2), 782-786
DOI 10.33218/001c.22201, PublikaID 365
Skotland T, Sandvig K (2021)
Transport of nanoparticles across the endothelial cell layer
Nano Today, 36, 101029
DOI 10.1016/j.nantod.2020.101029
Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
Cells, 10 (6)
DOI 10.3390/cells10061342, PubMed 34071546
Sønstevold T, Engedal N, Torgersen ML (2021)
Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
Cells, 10 (12)
DOI 10.3390/cells10123432, PubMed 34943939
Tan KW (2021)
First person - Kia Wee Tan
J. Cell Sci., 134 (14), jcs259055
DOI 10.1242/jcs.259055
Tan KW, Nähse V, Campsteijn C, Brech A, Schink KO, Stenmark H (2021)
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
J Cell Sci, 134 (14)
DOI 10.1242/jcs.258495, PubMed 34109410
Valko A, Perez-Pandolfo S, Sorianello E, Brech A, Wappner P, Melani M (2021)
Adaptation to hypoxia in Drosophila melanogaster requires autophagy
Autophagy, 18 (4), 909-920
DOI 10.1080/15548627.2021.1991191, PubMed 34793268
Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
Int J Pharm, 597, 120217
DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
Wiedlocha A, Haugsten EM, Zakrzewska M (2021)
Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
Cells, 10 (9)
DOI 10.3390/cells10092231, PubMed 34571880
Wirth M, Mouilleron S, Zhang W, Sjøttem E, Abudu YP, Jain A, Olsvik HL, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
J Mol Biol, 433 (15), 167049
DOI 10.1016/j.jmb.2021.167049, PubMed 34052024
Wirth M, Mouilleron S, Zhang W, Sjøttem E, Princely Abudu Y, Jain A, Lauritz Olsvik H, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
J Mol Biol, 433 (13), 166987
DOI 10.1016/j.jmb.2021.166987, PubMed 33845085
Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M (2021)
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
Proc Natl Acad Sci U S A, 118 (28)
DOI 10.1073/pnas.2024596118, PubMed 34244439
Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904
Øverbye A, Torgersen ML, Sønstevold T, Iversen TG, Mørch Ý, Skotland T, Sandvig K (2021)
Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: toxicity and changes in the proteome of breast, colon and prostate cancer cells
Nanotoxicology, 15 (7), 865-884
DOI 10.1080/17435390.2021.1924888, PubMed 34047629

Publications 2020

Buratta S, Tancini B, Sagini K, Delo F, Chiaradia E, Urbanelli L, Emiliani C (2020)
Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular
Int J Mol Sci, 21 (7)
DOI 10.3390/ijms21072576, PubMed 32276321
Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
iScience, 23 (6), 101154
DOI 10.1016/j.isci.2020.101154, PubMed 32450518
Dillard P, Lie M, Baken E, Lobert VH, Benard E, Köksal H, Inderberg EM, Wälchli S (2020)
Colorectal cysts as a validating tool for CAR therapy
BMC Biotechnol, 20 (1), 30
DOI 10.1186/s12896-020-00623-0, PubMed 32487146
Grønvold B, Ali MM, Remberger M, Mattsson J, Egeland T, Lundin KU, Myhre AE, Abrahamsen IW, Heldal D, Dybedal I, Tjønnfjord GE, Fløisand Y, Gedde-Dahl T (2020)
HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation
Bone Marrow Transplant, 55 (8), 1658-1661
DOI 10.1038/s41409-020-0827-3, PubMed 32054997
Jacomin AC, Gohel R, Hussain Z, Varga A, Maruzs T, Eddison M, Sica M, Jain A, Moffat KG, Johansen T, Jenny A, Juhasz G, Nezis IP (2020)
Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
Life Sci Alliance, 4 (2)
DOI 10.26508/lsa.202000965, PubMed 33318080
Jacomin AC, Petridi S, Di Monaco M, Bhujabal Z, Jain A, Mulakkal NC, Palara A, Powell EL, Chung B, Zampronio C, Jones A, Cameron A, Johansen T, Nezis IP (2020)
Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
Cell Rep, 31 (8), 107695
DOI 10.1016/j.celrep.2020.107695, PubMed 32460019
Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C (2020)
Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
Nat Commun, 11 (1), 440
DOI 10.1038/s41467-020-14343-8, PubMed 31974402
Jena KK, Mehto S, Nath P, Chauhan NR, Sahu R, Dhar K, Das SK, Kolapalli SP, Murmu KC, Jain A, Krishna S, Sahoo BS, Chattopadhyay S, Rusten TE, Prasad P, Chauhan S, Chauhan S (2020)
Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response
EMBO Rep, 21 (9), e50051
DOI 10.15252/embr.202050051, PubMed 32715615
Jendryczko K, Chudzian J, Skinder N, Opaliński Ł, Rzeszótko J, Wiedlocha A, Otlewski J, Szlachcic A (2020)
FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102992, PubMed 33076489
Kolapalli SP, Sahu R, Chauhan NR, Jena KK, Mehto S, Das SK, Jain A, Rout M, Dash R, Swain RK, Lee DY, Rusten TE, Chauhan S, Chauhan S (2020)
RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
Cancer Res, 81 (2), 315-331
DOI 10.1158/0008-5472.CAN-20-1871, PubMed 33067265
Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
Nat Cell Biol, 22 (8), 973-985
DOI 10.1038/s41556-020-0549-1, PubMed 32753672
Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
Nat Cell Biol, 22 (10), 1286
DOI 10.1038/s41556-020-0574-0, PubMed 32788721
Kumar S, Jain A, Choi SW, Peixoto Duarte da Silva G, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB
Autophagy, 16 (12), 2305-2306
DOI 10.1080/15548627.2020.1837423, PubMed 33070669
Laiouar S, Berns N, Brech A, Riechmann V (2020)
RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism
Curr Biol, 30 (7), 1177-1188.e5
DOI 10.1016/j.cub.2020.01.048, PubMed 32059769
Liese S, Wenzel EM, Kjos I, Rojas Molina R, Schultz SW, Brech A, Stenmark H, Raiborg C, Carlson A (2020)
Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
Proc Natl Acad Sci U S A, 117 (46), 28614-28624
DOI 10.1073/pnas.2014228117, PubMed 33139578
Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
Cell Mol Life Sci, 78 (3), 985-1009
DOI 10.1007/s00018-020-03551-6, PubMed 32447426
Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
J Mater Chem B, 8 (31), 6710-6738
DOI 10.1039/d0tb00861c, PubMed 32627783
Mastrangelopoulou M, Grigalavicius M, Raabe TH, Skarpen E, Juzenas P, Peng Q, Berg K, Theodossiou TA (2020)
Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
Cancer Rep (Hoboken), 5 (12), e1278
DOI 10.1002/cnr2.1278, PubMed 32737955
Munthe E, Raiborg C, Stenmark H, Wenzel EM (2020)
Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
J Cell Sci, 133 (13)
DOI 10.1242/jcs.244467, PubMed 32546530
Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation, 149, 170-179
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258
Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ (2020)
Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
EMBO J, 39 (24), e104948
DOI 10.15252/embj.2020104948, PubMed 33226137
Omsland M, Andresen V, Gullaksen SE, Ayuda-Durán P, Popa M, Hovland R, Brendehaug A, Enserink J, McCormack E, Gjertsen BT (2020)
Tyrosine kinase inhibitors and interferon-α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines
FASEB J, 34 (3), 3773-3791
DOI 10.1096/fj.201802061RR, PubMed 31945226
Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S (2020)
Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061516, PubMed 32531927
Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
Biomacromolecules, 21 (4), 1489-1498
DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
Cells, 9 (5)
DOI 10.3390/cells9051171, PubMed 32397238
Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
J Cell Biol, 219 (8)
DOI 10.1083/jcb.202003063, PubMed 32479595
Radulovic M, Stenmark H (2020)
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793
Remberger M, Grønvold B, Ali M, Mattsson J, Egeland T, Lundin KU, Myhre A, Abrahamsen I, Heldal D, Dybedal I, Tjønnfjord GE, Gedde-Dahl T, Fløisand Y (2020)
The CD34⁺ Cell Dose Matters in Hematopoietic Stem Cell Transplantation with Peripheral Blood Stem Cells from Sibling Donors
Clin Hematol Int, 2 (2), 74-81
DOI 10.2991/chi.d.200221.001, PubMed 34595446
Skotland T, Kavaliauskiene S, Sandvig K (2020)
The role of lipid species in membranes and cancer-related changes
Cancer Metastasis Rev, 39 (2), 343-360
DOI 10.1007/s10555-020-09872-z, PubMed 32314087
Skotland T, Sagini K, Sandvig K, Llorente A (2020)
An emerging focus on lipids in extracellular vesicles
Adv Drug Deliv Rev, 159, 308-321
DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
Toxicology, 433-434, 152405
DOI 10.1016/j.tox.2020.152405, PubMed 32044396
Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
Biological response and cytotoxicity induced by lipid nanocapsules
J Nanobiotechnology, 18 (1), 5
DOI 10.1186/s12951-019-0567-y, PubMed 31907052
Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
J Biomed Nanotechnol, 16 (4), 432-445
DOI 10.1166/jbn.2020.2906, PubMed 32970976
Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J Biol Chem, 296, 100179
DOI 10.1074/jbc.RA120.015285, PubMed 33303632
Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
J Biomed Nanotechnol, 16 (4), 419-431
DOI 10.1166/jbn.2020.2911, PubMed 32970975
Tsjokajev A, Røberg-Larsen H, Wilson SR, Dyve Lingelem AB, Skotland T, Sandvig K, Lundanes E (2020)
Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase
J Chromatogr B Analyt Technol Biomed Life Sci, 1160, 122384
DOI 10.1016/j.jchromb.2020.122384, PubMed 32971370
Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
Analytical techniques for multiplex analysis of protein biomarkers
Expert Rev Proteomics, 17 (4), 257-273
DOI 10.1080/14789450.2020.1763174, PubMed 32427033
Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372
Welsh JA, van der Pol E, Bettin BA, Carter DRF, Hendrix A, Lenassi M, Langlois MA, Llorente A, van de Nes AS, Nieuwland R, Tang V, Wang L, Witwer KW, Jones JC (2020)
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
J Extracell Vesicles, 9 (1), 1816641
DOI 10.1080/20013078.2020.1816641, PubMed 33062218
Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020417, PubMed 32053965
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (8), 868-879
DOI 10.1038/s41590-020-0730-5, PubMed 32690950
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
Author Correction: STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (11), 1468-1469
DOI 10.1038/s41590-020-0803-5, PubMed 32929276

Publications 2019

Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nähse V, Jaszczyszyn Y, Lachages AM, Dutrillaux B, Thermes C, Debatisse M, Chen CL (2019)
Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
Nat Commun, 10 (1), 5693
DOI 10.1038/s41467-019-13674-5, PubMed 31836700
Dillard C, Rusten TE (2019)
Cell Competition Triggers Suicide by Autophagy
Dev Cell, 51 (1), 4-5
DOI 10.1016/j.devcel.2019.09.014, PubMed 31593651
Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE et al. (2019)
NAD⁺ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Nat Commun, 10 (1), 5284
DOI 10.1038/s41467-019-13172-8, PubMed 31754102
Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
Cell Rep, 28 (7), 1907-1922.e6
DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255
Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279
Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, Johansen T (2019)
The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS
Front Genet, 10, 249
DOI 10.3389/fgene.2019.00249, PubMed 30984240
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E et al. (2019)
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
Nat Commun, 10 (1), 4176
DOI 10.1038/s41467-019-12094-9, PubMed 31519908
Khezri R, Rusten TE (2019)
Autophagy and Tumorigenesis in Drosophila
Adv Exp Med Biol, 1167, 113-127
DOI 10.1007/978-3-030-23629-8_7, PubMed 31520352
Khezri R, Rusten TE (2019)
Correction to: Autophagy and Tumorigenesis in Drosophila
Adv Exp Med Biol, 1167, C1
DOI 10.1007/978-3-030-23629-8_15, PubMed 33306185
Kumar S, Gu Y, Abudu YP, Bruun JA, Jain A, Farzam F, Mudd M, Anonsen JH, Rusten TE, Kasof G, Ktistakis N, Lidke KA, Johansen T, Deretic V (2019)
Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation
Dev Cell, 49 (1), 130-144.e6
DOI 10.1016/j.devcel.2019.01.027, PubMed 30827897
Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
J Biol Chem, 294 (20), 8197-8217
DOI 10.1074/jbc.RA118.002829, PubMed 30926605
Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S (2019)
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy
Mol Cell, 73 (3), 429-445.e7
DOI 10.1016/j.molcel.2018.11.018, PubMed 30612879
Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC (2019)
The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses
J Pharmacol Exp Ther, 370 (3), 581-592
DOI 10.1124/jpet.119.258012, PubMed 30940695
Nguéa P A, Robertson J, Herrera MC, Chymkowitch P, Enserink JM (2019)
Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
J Biol Chem, 294 (49), 18784-18795
DOI 10.1074/jbc.RA119.009721, PubMed 31676685
Palomo-Guerrero M, Fadó R, Casas M, Pérez-Montero M, Baena M, Helmer PO, Domínguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N (2019)
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
Elife, 8
DOI 10.7554/eLife.51063, PubMed 31868590
Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
Int J Nanomedicine, 14, 6269-6285
DOI 10.2147/IJN.S208938, PubMed 31496685
Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131
Pölönen P, Jawahar Deen A, Leinonen HM, Jyrkkänen HK, Kuosmanen S, Mononen M, Jain A, Tuomainen T, Pasonen-Seppänen S, Hartikainen JM, Mannermaa A, Nykter M, Tavi P, Johansen T, Heinäniemi M, Levonen AL (2019)
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Oncogene, 38 (50), 7473-7490
DOI 10.1038/s41388-019-0956-6, PubMed 31444413
Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
J Extracell Vesicles, 8 (1), 1684862
DOI 10.1080/20013078.2019.1684862, PubMed 31762963
Shoemaker CJ, Huang TQ, Weir NR, Polyakov NJ, Schultz SW, Denic V (2019)
CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
PLoS Biol, 17 (4), e2007044
DOI 10.1371/journal.pbio.2007044, PubMed 30933966
Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H (2019)
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
PLoS Pathog, 15 (3), e1007684
DOI 10.1371/journal.ppat.1007684, PubMed 30883606
Skotland T, Sandvig K (2019)
The role of PS 18:0/18:1 in membrane function
Nat Commun, 10 (1), 2752
DOI 10.1038/s41467-019-10711-1, PubMed 31227693
Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
Nat Commun, 10 (1), 2850
DOI 10.1038/s41467-019-10794-w, PubMed 31253801
Sneeggen M, Schink KO, Stenmark H (2019)
Tumor suppression by control of matrix metalloproteinase recycling
Mol Cell Oncol, 6 (6), e1646606
DOI 10.1080/23723556.2019.1646606, PubMed 31692886
Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M (2019)
Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
Toxins (Basel), 11 (6)
DOI 10.3390/toxins11060350, PubMed 31216687
Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
Nanotoxicology, 13 (6), 761-782
DOI 10.1080/17435390.2019.1576238, PubMed 30760074
Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
Cells, 8 (6)
DOI 10.3390/cells8060518, PubMed 31146385
Tancini B, Buratta S, Sagini K, Costanzi E, Delo F, Urbanelli L, Emiliani C (2019)
Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders
Genes (Basel), 10 (7)
DOI 10.3390/genes10070510, PubMed 31284546
Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194
Vietri M, Radulovic M, Stenmark H (2019)
The many functions of ESCRTs
Nat Rev Mol Cell Biol, 21 (1), 25-42
DOI 10.1038/s41580-019-0177-4, PubMed 31705132
Zakrzewska M, Opalinski L, Haugsten EM, Otlewski J, Wiedlocha A (2019)
Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
Int J Mol Sci, 20 (8)
DOI 10.3390/ijms20081826, PubMed 31013829
Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, 104 (5), e229
DOI 10.3324/haematol.2019.220533, PubMed 31040234
Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
ESCRT-mediated phagophore sealing during mitophagy
Autophagy, 16 (5), 826-841
DOI 10.1080/15548627.2019.1639301, PubMed 31366282

Publications 2018

Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
J Control Release, 293, 183-192
DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
Herrera M, Llorens C, Rodríguez M, Herrera A, Ramos R, Gil B, Candia A, Larriba MJ, Garre P, Earl J, Rodríguez-Garrote M, Caldés T, Bonilla F, Carrato A, García-Barberán V, Peña C (2018)
Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer
Mol Cancer, 17 (1), 114
DOI 10.1186/s12943-018-0863-4, PubMed 30075793
Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 11698-11711
DOI 10.1093/nar/gky846, PubMed 30247619
Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 12188-12189
DOI 10.1093/nar/gky1102, PubMed 30395271
Hurem S, Gomes T, Brede DA, Mayer I, Lobert VH, Mutoloki S, Gutzkow KB, Teien HC, Oughton D, Aleström P, Lyche JL (2018)
Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
Ecotoxicol Environ Saf, 154, 19-26
DOI 10.1016/j.ecoenv.2018.02.031, PubMed 29453161
Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290
Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, Otlewski J, Zakrzewska M (2018)
Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation
J Mol Biol, 430 (21), 4087-4101
DOI 10.1016/j.jmb.2018.08.004, PubMed 30099027
Kruitwagen T, Chymkowitch P, Denoth-Lippuner A, Enserink J, Barral Y (2018)
Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
Cell, 175 (3), 780-795.e15
DOI 10.1016/j.cell.2018.09.012, PubMed 30318142
Kumar S, Jain A, Farzam F, Jia J, Gu Y, Choi SW, Mudd MH, Claude-Taupin A, Wester MJ, Lidke KA, Rusten TE, Deretic V (2018)
Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins
J Cell Biol, 217 (3), 997-1013
DOI 10.1083/jcb.201708039, PubMed 29420192
Malerød L, Le Borgne R, Lie-Jensen A, Eikenes ÅH, Brech A, Liestøl K, Stenmark H, Haglund K (2018)
Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
EMBO J, 37 (13)
DOI 10.15252/embj.201797741, PubMed 29858227
Mejlvang J, Olsvik H, Svenning S, Bruun JA, Abudu YP, Larsen KB, Brech A, Hansen TE, Brenne H, Hansen T, Stenmark H, Johansen T (2018)
Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
J Cell Biol, 217 (10), 3640-3655
DOI 10.1083/jcb.201711002, PubMed 30018090
Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982
Nouri H, Monnier AF, Fossum-Raunehaug S, Maciag-Dorszynska M, Cabin-Flaman A, Képès F, Wegrzyn G, Szalewska-Palasz A, Norris V, Skarstad K, Janniere L (2018)
Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
DNA Res, 25 (6), 641-653
DOI 10.1093/dnares/dsy031, PubMed 30256918
Olsvik HL, Svenning S, Abudu YP, Brech A, Stenmark H, Johansen T, Mejlvang J (2018)
Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation
Autophagy, 15 (1), 182-183
DOI 10.1080/15548627.2018.1532265, PubMed 30295124
Osteikoetxea X, Benke M, Rodriguez M, Pálóczi K, Sódar BW, Szvicsek Z, Szabó-Taylor K, Vukman KV, Kittel Á, Wiener Z, Vékey K, Harsányi L, Szűcs Á, Turiák L, Buzás EI (2018)
Detection and proteomic characterization of extracellular vesicles in human pancreatic juice
Biochem Biophys Res Commun, 499 (1), 37-43
DOI 10.1016/j.bbrc.2018.03.107, PubMed 29550476
Popēna I, Ābols A, Saulīte L, Pleiko K, Zandberga E, Jēkabsons K, Endzeliņš E, Llorente A, Linē A, Riekstiņa U (2018)
Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
Cell Commun Signal, 16 (1), 17
DOI 10.1186/s12964-018-0229-y, PubMed 29690889
Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H (2018)
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
EMBO J, 37 (21)
DOI 10.15252/embj.201899753, PubMed 30314966
Radulovic M, Stenmark H (2018)
ESCRTs in membrane sealing
Biochem Soc Trans, 46 (4), 773-778
DOI 10.1042/BST20170435, PubMed 29903934
Sandvig K, Kavaliauskiene S, Skotland T (2018)
Clathrin-independent endocytosis: an increasing degree of complexity
Histochem Cell Biol, 150 (2), 107-118
DOI 10.1007/s00418-018-1678-5, PubMed 29774430
Skotland T, Hessvik NP, Sandvig K, Llorente A (2018)
Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
J Lipid Res, 60 (1), 9-18
DOI 10.1194/jlr.R084343, PubMed 30076207
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E et al. (2018)
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
J Extracell Vesicles, 7 (1), 1535750
DOI 10.1080/20013078.2018.1535750, PubMed 30637094
Vietri M, Stenmark H (2018)
Orchestrating Nuclear Envelope Sealing during Mitosis
Dev Cell, 47 (5), 541-542
DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298
Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nähse V, Carlson A, Brech A, Stenmark H, Raiborg C (2018)
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Nat Commun, 9 (1), 2932
DOI 10.1038/s41467-018-05345-8, PubMed 30050131
Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
Light-enhanced VEGF₁₂₁/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
J Control Release, 288, 161-172
DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739
Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM, Bjørn Tore Gjertsen Group, Emmet McCormack Group (2018)
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, Online ahead of print (in press) (Retracted)
DOI 10.3324/haematol.2018.189399, PubMed 29748445
Zhen Y, Haugsten EM, Singh SK, Wesche J (2018)
Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4
Biochemistry, 57 (26), 3807-3816
DOI 10.1021/acs.biochem.8b00120, PubMed 29812912

Publications 2017

Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
DOI 10.1111/tra.12468, PubMed 28067430
Boye E, Skotland T, Østerud B, Nissen-Meyer J (2017)
Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
EMBO Rep, 18 (3), 351-354
DOI 10.15252/embr.201643540, PubMed 28167676
Cambier S, Røgeberg M, Georgantzopoulou A, Serchi T, Karlsson C, Verhaegen S, Iversen TG, Guignard C, Kruszewski M, Hoffmann L, Audinot JN, Ropstad E, Gutleb AC (2017)
Fate and effects of silver nanoparticles on early life-stage development of zebrafish (Danio rerio) in comparison to silver nitrate
Sci Total Environ, 610-611, 972-982
DOI 10.1016/j.scitotenv.2017.08.115, PubMed 28838034
Chymkowitch P, Enserink JM (2017)
Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
Biochim Biophys Acta Gene Regul Mech, 1861 (4), 310-319
DOI 10.1016/j.bbagrm.2017.11.001, PubMed 29127063
Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM (2017)
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
DOI 10.1073/pnas.1615093114, PubMed 28096404
Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
BMC Cancer, 17 (1), 730
DOI 10.1186/s12885-017-3737-z, PubMed 29121858
Enserink J, Nguéa P A, Chymkowitch P (2017)
Anabolic transcription: Secrets of the sumo diet
Cell Cycle, 16 (7), 593-594
DOI 10.1080/15384101.2017.1294945, PubMed 28278057
Enserink JM (2017)
Regulation of Cellular Processes by SUMO: Understudied Topics
Adv Exp Med Biol, 963, 89-97
DOI 10.1007/978-3-319-50044-7_5, PubMed 28197907
Enserink JM (2017)
Sumo during stress: When transcription takes a pause (comment on DOI.10.1002/bies.201600263)
Bioessays, 39 (6)
DOI 10.1002/bies.201700065, PubMed 28464310
Flåtten I, Helgesen E, Pedersen IB, Waldminghaus T, Rothe C, Taipale R, Johnsen L, Skarstad K (2017)
Phenotypes of dnaX_E145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
J Bacteriol, 199 (24)
DOI 10.1128/JB.00412-17, PubMed 28947673
Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E (2017)
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611
Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
ChemMedChem, 12 (8), 613-620
DOI 10.1002/cmdc.201700108, PubMed 28334511
Hessvik NP, Llorente A (2017)
Current knowledge on exosome biogenesis and release
Cell Mol Life Sci, 75 (2), 193-208
DOI 10.1007/s00018-017-2595-9, PubMed 28733901
Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol, 216 (12), 4217-4233
DOI 10.1083/jcb.201611073, PubMed 29030394
Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876
Katheder NS, Rusten TE (2017)
Microenvironment and tumors-a nurturing relationship
Autophagy, 13 (7), 1241-1243
DOI 10.1080/15548627.2017.1310361, PubMed 28632995
Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
Protection against Shiga Toxins
Toxins (Basel), 9 (2)
DOI 10.3390/toxins9020044, PubMed 28165371
Krzyscik MA, Zakrzewska M, Sørensen V, Sokolowska-Wedzina A, Lobocki M, Swiderska KW, Krowarsch D, Wiedlocha A, Otlewski J (2017)
Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
ACS Omega, 2 (7), 3792-3805
DOI 10.1021/acsomega.7b00116, PubMed 30023704
Labieniec-Watala M, Szwed M, Hertel J, Wisnik E (2017)
Low Concentrations of Cationic PAMAM Dendrimers Affect Lymphocyte Respiration in In vitro Studies
Curr Pharm Biotechnol, 18 (2), 150-157
DOI 10.2174/1389201017666161229153018, PubMed 28034293
Lång A, Eriksson J, Schink KO, Lång E, Blicher P, Połeć A, Brech A, Dalhus B, Bøe SO (2017)
Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
Nucleus, 8 (4), 404-420
DOI 10.1080/19491034.2017.1306161, PubMed 28402725
Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2017)
Correction: TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
J Cell Sci, 130 (6), 1194
DOI 10.1242/jcs.202499, PubMed 28298613
Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
PLoS One, 12 (1), e0170716
DOI 10.1371/journal.pone.0170716, PubMed 28114329
O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE (2017)
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
Nat Cell Biol, 19 (12), 1412-1423
DOI 10.1038/ncb3631, PubMed 29084199
Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290
Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
A novel community driven software for functional enrichment analysis of extracellular vesicles data
J Extracell Vesicles, 6 (1), 1321455
DOI 10.1080/20013078.2017.1321455, PubMed 28717418
Pedersen IB, Helgesen E, Flåtten I, Fossum-Raunehaug S, Skarstad K (2017)
SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
Nucleic Acids Res, 45 (11), 6471-6485
DOI 10.1093/nar/gkx263, PubMed 28407100
Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K (2017)
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
Oncotarget, 8 (14), 22606-22615
DOI 10.18632/oncotarget.15146, PubMed 28186983
Rahman MM, Franch-Marro X, Maestro JL, Martin D, Casali A (2017)
Local Juvenile Hormone activity regulates gut homeostasis and tumor growth in adult Drosophila
Sci Rep, 7 (1), 11677
DOI 10.1038/s41598-017-11199-9, PubMed 28916802
Raiborg C, Schink KO, Stenmark H (2017)
Suppressing mTORC1 on the lysosome
EMBO J, 36 (13), 1809-1810
DOI 10.15252/embj.201797469, PubMed 28623241
Sadovska L, Zandberga E, Sagini K, Jēkabsons K, Riekstiņa U, Kalniņa Z, Llorente A, Linē A (2017)
A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication
Biochem Biophys Res Commun, 495 (2), 1930-1935
DOI 10.1016/j.bbrc.2017.12.072, PubMed 29248729
Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
Exp Cell Res, 357 (1), 67-78
DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044
Skotland T (2017)
Injection of nanoparticles into cloven-hoof animals: Asking for trouble
Theranostics, 7 (19), 4877-4878
DOI 10.7150/thno.22420, PubMed 29187910
Skotland T, Sandvig K, Llorente A (2017)
Lipids in exosomes: Current knowledge and the way forward
Prog Lipid Res, 66, 30-41
DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
Sulheim E, Iversen TG, To Nakstad V, Klinkenberg G, Sletta H, Schmid R, Hatletveit AR, Wågbø AM, Sundan A, Skotland T, Sandvig K, Mørch Ý (2017)
Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles
Int J Mol Sci, 18 (11)
DOI 10.3390/ijms18112454, PubMed 29156588
Søreng K, Knævelsrud H, Holland P, Simonsen A (2017)
HS1BP3 inhibits autophagy by regulation of PLD1
Autophagy, 13 (5), 985-986
DOI 10.1080/15548627.2017.1291483, PubMed 28318354
Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM (2017)
A vital sugar code for ricin toxicity
Cell Res, 27 (11), 1351-1364
DOI 10.1038/cr.2017.116, PubMed 28925387
Thorvaldsen TE (2017)
Targeting Tankyrase to Fight WNT-dependent Tumours
Basic Clin Pharmacol Toxicol, 121 (2), 81-88
DOI 10.1111/bcpt.12786, PubMed 28371398
Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
PLoS One, 12 (1), e0170508
DOI 10.1371/journal.pone.0170508, PubMed 28107521
Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
J Cell Sci, 130 (17), 2867-2882
DOI 10.1242/jcs.202408, PubMed 28733455
Tusco R, Jacomin AC, Jain A, Penman BS, Larsen KB, Johansen T, Nezis IP (2017)
Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
Nat Commun, 8 (1), 1264
DOI 10.1038/s41467-017-01287-9, PubMed 29097655
Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
J Extracell Vesicles, 6 (1), 1344087
DOI 10.1080/20013078.2017.1344087, PubMed 28804597
Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM (2017)
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
G3 (Bethesda), 7 (6), 1753-1766
DOI 10.1534/g3.117.042317, PubMed 28428242
Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
Oncotarget, 8 (44), 76921-76934
DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
Sci Rep, 6, 30336
DOI 10.1038/srep30336, PubMed 27458147
Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
Oncotarget, 7 (18), 25443-60
DOI 10.18632/oncotarget.8327, PubMed 27029001
Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J (2016)
Identification of new FGF1 binding partners-Implications for its intracellular function
IUBMB Life, 68 (3), 242-51
DOI 10.1002/iub.1480, PubMed 26840910
Campsteijn C, Vietri M, Stenmark H (2016)
Novel ESCRT functions in cell biology: spiraling out of control?
Curr Opin Cell Biol, 41, 1-8
DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044
Christ L, Raiborg C, Wenzel EM, Campsteijn C, Stenmark H (2016)
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
Trends Biochem Sci, 42 (1), 42-56
DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649
Christ L, Wenzel EM, Liestøl K, Raiborg C, Campsteijn C, Stenmark H (2016)
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
J Cell Biol, 212 (5), 499-513
DOI 10.1083/jcb.201507009, PubMed 26929449
Cordara G, van Eerde A, Grahn EM, Winter HC, Goldstein IJ, Krengel U (2016)
An Unusual Member of the Papain Superfamily: Mapping the Catalytic Cleft of the Marasmius oreades agglutinin (MOA) with a Caspase Inhibitor
PLoS One, 11 (2), e0149407
DOI 10.1371/journal.pone.0149407, PubMed 26901797
Endzeliņš E, Melne V, Kalniņa Z, Lietuvietis V, Riekstiņa U, Llorente A, Linē A (2016)
Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review
Mol Cancer, 15 (1), 41
DOI 10.1186/s12943-016-0523-5, PubMed 27189160
Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C et al. (2016)
Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
ACS Nano, 10 (4), 3886-99
DOI 10.1021/acsnano.5b08015, PubMed 26978483
Fykerud TA, Knudsen LM, Totland MZ, Sørensen V, Dahal-Koirala S, Lothe RA, Brech A, Leithe E (2016)
Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
Cell Cycle, 15 (21), 2943-2957
DOI 10.1080/15384101.2016.1231280, PubMed 27625181
Halsne R, Tandberg JI, Lobert VH, Østby GC, Thoen E, Ropstad E, Verhaegen S (2016)
Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro
Toxicol Lett, 259, 95-107
DOI 10.1016/j.toxlet.2016.08.004, PubMed 27511595
Haugsten EM, Sørensen V, Kunova Bosakova M, de Souza GA, Krejci P, Wiedlocha A, Wesche J (2016)
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
J Proteome Res, 15 (10), 3841-3855
DOI 10.1021/acs.jproteome.6b00652, PubMed 27615514
Helgesen E, Fossum-Raunehaug S, Skarstad K (2016)
Lack of the H-NS Protein Results in Extended and Aberrantly Positioned DNA during Chromosome Replication and Segregation in Escherichia coli
J Bacteriol, 198 (8), 1305-16
DOI 10.1128/JB.00919-15, PubMed 26858102
Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ (2016)
A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking
PLoS One, 11 (6), e0156893
DOI 10.1371/journal.pone.0156893, PubMed 27300140
Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
PIKfyve inhibition increases exosome release and induces secretory autophagy
Cell Mol Life Sci, 73 (24), 4717-4737
DOI 10.1007/s00018-016-2309-8, PubMed 27438886
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
Nat Commun, 7, 13889
DOI 10.1038/ncomms13889, PubMed 28004827
Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
Oncotarget, 7 (48), 79885-79900
DOI 10.18632/oncotarget.13089, PubMed 27829218
Li Y, Hessvik NP, Danbolt NC, Holen T (2016)
A large-scale quantitative EM study on activation of olfactory glands shows no effect of cholinergic agents
Microscopy (Oxf), 65 (5), 438-443
DOI 10.1093/jmicro/dfw028, PubMed 27460022
Lie-Jensen A, Haglund K (2016)
Antibody Staining in Drosophila Germaria
Methods Mol Biol, 1457, 19-33
DOI 10.1007/978-1-4939-3795-0_3, PubMed 27557571
Lobert VH, Mouradov D, Heath JK (2016)
Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer
Adv Exp Med Biol, 916, 411-37
DOI 10.1007/978-3-319-30654-4_18, PubMed 27165364
Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M (2016)
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
Sci Signal, 9 (411), ra8
DOI 10.1126/scisignal.aad0848, PubMed 26787452
Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2016)
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
J Cell Sci, 129 (19), 3562-3573
DOI 10.1242/jcs.190017, PubMed 27562068
Nähse V, Christ L, Stenmark H, Campsteijn C (2016)
The Abscission Checkpoint: Making It to the Final Cut
Trends Cell Biol, 27 (1), 1-11
DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282
Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H (2016)
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
PLoS One, 11 (8), e0160507
DOI 10.1371/journal.pone.0160507, PubMed 27482906
Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP (2016)
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer
Nat Commun, 7, 10318
DOI 10.1038/ncomms10318, PubMed 26754771
Raiborg C, Stenmark H (2016)
Plasma membrane repairs by small GTPase Rab3a
J Cell Biol, 213 (6), 613-5
DOI 10.1083/jcb.201606006, PubMed 27325788
Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
Phosphoinositides in membrane contact sites
Biochem Soc Trans, 44 (2), 425-30
DOI 10.1042/BST20150190, PubMed 27068950
Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
ER-endosome contact sites in endosome positioning and protrusion outgrowth
Biochem Soc Trans, 44 (2), 441-6
DOI 10.1042/BST20150246, PubMed 27068952
Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
Data Brief, 7, 1171-1174
DOI 10.1016/j.dib.2016.03.067, PubMed 27761499
Schink KO, Tan KW, Stenmark H (2016)
Phosphoinositides in Control of Membrane Dynamics
Annu Rev Cell Dev Biol, 32, 143-171
DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122
Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D (2016)
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility
PLoS One, 11 (7), e0159473
DOI 10.1371/journal.pone.0159473, PubMed 27467079
Skotland T (2016)
How organizers of scientific meetings and journal editors could facilitate transfer of nanomedicine into the clinic
Eur. J. Nanomed., 8 (1), 61-63
DOI 10.1515/ejnm-2015-0048
Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
Eur J Cancer, 70, 122-132
DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
Skotland T, Ekroos K, Kavaliauskiene S, Bergan J, Kauhanen D, Lintonen T, Sandvig K (2016)
Determining the Turnover of Glycosphingolipid Species by Stable-Isotope Tracer Lipidomics
J Mol Biol, 428 (24 Pt A), 4856-4866
DOI 10.1016/j.jmb.2016.06.013, PubMed 27363608
Sundvold H, Sundvold-Gjerstad V, Malerød-Fjeld H, Haglund K, Stenmark H, Malerød L (2016)
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
Cell Cycle, 15 (5), 628-43
DOI 10.1080/15384101.2016.1146834, PubMed 27104745
Szymanska M, Fosdahl AM, Raiborg C, Dietrich M, Liestøl K, Stang E, Bertelsen V (2016)
Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3
Biochim Biophys Acta, 1863 (6 Pt A), 1179-88
DOI 10.1016/j.bbamcr.2016.03.011, PubMed 26975582
Tesikova M, Dezitter X, Nenseth HZ, Klokk TI, Mueller F, Hager GL, Saatcioglu F (2016)
Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element
J Biol Chem, 291 (22), 11899-910
DOI 10.1074/jbc.M115.684480, PubMed 27056330
Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
Oncotarget, 7 (52), 86871-86888
DOI 10.18632/oncotarget.13508, PubMed 27894086
Vietri M, Stenmark H, Campsteijn C (2016)
Closing a gap in the nuclear envelope
Curr Opin Cell Biol, 40, 90-97
DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712
Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
Eur J Pharm Sci, 98, 80-85
DOI 10.1016/j.ejps.2016.09.023, PubMed 27664330
Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ (2016)
Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport
Sci Rep, 6, 22721
DOI 10.1038/srep22721, PubMed 26949061

Publications 2015

Bauereiss A, Welzel O, Jung J, Grosse-Holz S, Lelental N, Lewczuk P, Wenzel EM, Kornhuber J, Groemer TW (2015)
Surface Trafficking of APP and BACE in Live Cells
Traffic, 16 (6), 655-75
DOI 10.1111/tra.12270, PubMed 25712587
Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P (2015)
Instability restricts signaling of multiple fibroblast growth factors
Cell Mol Life Sci, 72 (12), 2445-59
DOI 10.1007/s00018-015-1856-8, PubMed 25854632
Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A (2015)
Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
Oncotarget, 6 (14), 12436-51
DOI 10.18632/oncotarget.3814, PubMed 26002552
Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B (2015)
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
Autophagy, 11 (9), 1458-70
DOI 10.1080/15548627.2015.1067359, PubMed 26207339
Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
PLoS One, 10 (5), e0129214
DOI 10.1371/journal.pone.0129214, PubMed 26017782
Egeland EV, Boye K, Pettersen SJ, Haugen MH, Øyjord T, Malerød L, Flatmark K, Mælandsmo GM (2015)
Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
Clin Exp Metastasis, 32 (8), 755-67
DOI 10.1007/s10585-015-9742-1, PubMed 26349943
Eikenes ÅH, Malerød L, Christensen AL, Steen CB, Mathieu J, Nezis IP, Liestøl K, Huynh JR, Stenmark H, Haglund K (2015)
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
PLoS Genet, 11 (1), e1004904
DOI 10.1371/journal.pgen.1004904, PubMed 25635693
Eikenes ÅH, Malerød L, Lie-Jensen A, Sem Wegner C, Brech A, Liestøl K, Stenmark H, Haglund K (2015)
Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
Development, 142 (23), 4107-18
DOI 10.1242/dev.124370, PubMed 26628094
Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK (2015)
Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy
Autophagy, 11 (3), 460-71
DOI 10.1080/15548627.2015.1009797, PubMed 25749095
Flåtten I, Fossum-Raunehaug S, Taipale R, Martinsen S, Skarstad K (2015)
The DnaA Protein Is Not the Limiting Factor for Initiation of Replication in Escherichia coli
PLoS Genet, 11 (6), e1005276
DOI 10.1371/journal.pgen.1005276, PubMed 26047361
Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
Novel Furin Inhibitors with Potent Anti-infectious Activity
ChemMedChem, 10 (7), 1218-31
DOI 10.1002/cmdc.201500103, PubMed 25974265
Helgesen E, Fossum-Raunehaug S, Sætre F, Schink KO, Skarstad K (2015)
Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
Nucleic Acids Res, 43 (5), 2730-43
DOI 10.1093/nar/gkv146, PubMed 25722374
Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T (2015)
p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
J Biol Chem, 290 (24), 14945-62
DOI 10.1074/jbc.M115.656116, PubMed 25931115
Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
Biochem J, 470 (1), 23-37
DOI 10.1042/BJ20141562, PubMed 26251444
Klokk TI, Kavaliauskiene S, Sandvig K (2015)
Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic
Cell Mol Life Sci, 73 (6), 1301-16
DOI 10.1007/s00018-015-2049-1, PubMed 26407609
Kymre L, Simm R, Skotland T, Sandvig K (2015)
Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
Pathog Dis, 73 (9), ftv083
DOI 10.1093/femspd/ftv083, PubMed 26443836
Le Guyon S, Simm R, Rehn M, Römling U (2015)
Dissecting the cyclic di-guanylate monophosphate signalling network regulating motility in Salmonella enterica serovar Typhimurium
Environ Microbiol, 17 (4), 1310-20
DOI 10.1111/1462-2920.12580, PubMed 25059628
Raiborg C, Wenzel EM, Pedersen NM, Olsvik H, Schink KO, Schultz SW, Vietri M, Nisi V, Bucci C, Brech A, Johansen T, Stenmark H (2015)
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
Nature, 520 (7546), 234-8
DOI 10.1038/nature14359, PubMed 25855459
Raiborg C, Wenzel EM, Stenmark H (2015)
ER-endosome contact sites: molecular compositions and functions
EMBO J, 34 (14), 1848-58
DOI 10.15252/embj.201591481, PubMed 26041457
Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
Biochim Biophys Acta, 1858 (2), 281-8
DOI 10.1016/j.bbamem.2015.12.003, PubMed 26654782
Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
Molecules, 20 (7), 13313-23
DOI 10.3390/molecules200713313, PubMed 26205056
Słomińska-Wojewódzka M, Sandvig K (2015)
The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
Molecules, 20 (6), 9816-46
DOI 10.3390/molecules20069816, PubMed 26023941
Sokołowska I, Piłka ES, Sandvig K, Węgrzyn G, Słomińska-Wojewódzka M (2015)
Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
BMC Cell Biol, 16, 1
DOI 10.1186/s12860-015-0047-7, PubMed 25655076
Sternemalm J, Geimer S, Frikstad KA, Schink KO, Stokke T, Patzke S (2015)
CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
PLoS One, 10 (8), e0134789
DOI 10.1371/journal.pone.0134789, PubMed 26241740
Szalai P, Hagen LK, Sætre F, Luhr M, Sponheim M, Øverbye A, Mills IG, Seglen PO, Engedal N (2015)
Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
Exp Cell Res, 333 (1), 21-38
DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710
Theodossiou TA, Wälchli S, Olsen CE, Skarpen E, Berg K (2015)
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
ACS Chem Biol, 11 (1), 251-62
DOI 10.1021/acschembio.5b00734, PubMed 26569462
Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443
Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H (2015)
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 522 (7555), 231-5
DOI 10.1038/nature14408, PubMed 26040712
Wendel T, Zhen Y, Suo Z, Bruheim S, Wiedlocha A (2015)
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
Exp Cell Res, 340 (2), 220-6
DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184
Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M et al. (2015)
Biological properties of extracellular vesicles and their physiological functions
J Extracell Vesicles, 4, 27066
DOI 10.3402/jev.v4.27066, PubMed 25979354
Zhen Y, Stenmark H (2015)
Cellular functions of Rab GTPases at a glance
J Cell Sci, 128 (17), 3171-6
DOI 10.1242/jcs.166074, PubMed 26272922
Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
Identification of prostate cancer biomarkers in urinary exosomes
Oncotarget, 6 (30), 30357-76
DOI 10.18632/oncotarget.4851, PubMed 26196085
Øvrebø JI, Campsteijn C, Kourtesis I, Hausen H, Raasholm M, Thompson EM (2015)
Functional specialization of chordate CDK1 paralogs during oogenic meiosis
Cell Cycle, 14 (6), 880-93
DOI 10.1080/15384101.2015.1006000, PubMed 25714331

Publications 2014

Anda S, Boye E, Grallert B (2014)
Cell-cycle analyses using thymidine analogues in fission yeast
PLoS One, 9 (2), e88629
DOI 10.1371/journal.pone.0088629, PubMed 24551125
Asp N, Pust S, Sandvig K (2014)
Flotillin depletion affects ErbB protein levels in different human breast cancer cells
Biochim Biophys Acta, 1843 (9), 1987-96
DOI 10.1016/j.bbamcr.2014.04.013, PubMed 24747692
Bergan J, Skotland T, Lingelem AB, Simm R, Spilsberg B, Lindbäck T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2014)
The ether lipid precursor hexadecylglycerol protects against Shiga toxins
Cell Mol Life Sci, 71 (21), 4285-300
DOI 10.1007/s00018-014-1624-1, PubMed 24740796
Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
J Control Release, 182, 58-66
DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464
Cordara G, Winter HC, Goldstein IJ, Krengel U, Sandvig K (2014)
The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis
Biochem Biophys Res Commun, 447 (4), 586-9
DOI 10.1016/j.bbrc.2014.04.043, PubMed 24747075
Danks GB, Raasholm M, Campsteijn C, Long AM, Manak JR, Lenhard B, Thompson EM (2014)
Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest
Mol Biol Evol, 32 (3), 585-99
DOI 10.1093/molbev/msu336, PubMed 25525214
Demarco RS, Eikenes ÅH, Haglund K, Jones DL (2014)
Investigating spermatogenesis in Drosophila melanogaster
Methods, 68 (1), 218-27
DOI 10.1016/j.ymeth.2014.04.020, PubMed 24798812
Fossum-Raunehaug S, Helgesen E, Stokke C, Skarstad K (2014)
Escherichia coli SeqA structures relocalize abruptly upon termination of origin sequestration during multifork DNA replication
PLoS One, 9 (10), e110575
DOI 10.1371/journal.pone.0110575, PubMed 25333813
Haugsten EM, Brech A, Liestøl K, Norman JC, Wesche J (2014)
Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling
Traffic, 15 (6), 665-83
DOI 10.1111/tra.12168, PubMed 24589086
Hermansson E, Schultz S, Crowther D, Linse S, Winblad B, Westermark G, Johansson J, Presto J (2014)
The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster
Dis Model Mech, 7 (6), 659-65
DOI 10.1242/dmm.014787, PubMed 24682783
Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
Traffic, 15 (12), 1390-405
DOI 10.1111/tra.12227, PubMed 25216107
Kvalvaag AS, Pust S, Sandvig K (2014)
Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
Commun Integr Biol, 7 (1), e28129
DOI 10.4161/cib.28129, PubMed 24778763
Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
MAbs, 6 (4), 1038-50
DOI 10.4161/mabs.28207, PubMed 24525727
Morigen M, Flåtten I, Skarstad K (2014)
The Escherichia coli datA site promotes proper regulation of cell division
Microbiology (Reading), 160 (Pt 4), 703-710
DOI 10.1099/mic.0.074898-0, PubMed 24574433
Odsbu I, Skarstad K (2014)
DNA compaction in the early part of the SOS response is dependent on RecN and RecA
Microbiology (Reading), 160 (Pt 5), 872-882
DOI 10.1099/mic.0.075051-0, PubMed 24615185
Oppelt A, Haugsten EM, Zech T, Danielsen HE, Sveen A, Lobert VH, Skotheim RI, Wesche J (2014)
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
Biochem J, 461 (3), 383-90
DOI 10.1042/BJ20140132, PubMed 24840251
Palibrk V, Lång E, Lång A, Schink KO, Rowe AD, Bøe SO (2014)
Promyelocytic leukemia bodies tether to early endosomes during mitosis
Cell Cycle, 13 (11), 1749-55
DOI 10.4161/cc.28653, PubMed 24675887
Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
Regulation of exosome release by glycosphingolipids and flotillins
FEBS J, 281 (9), 2214-27
DOI 10.1111/febs.12775, PubMed 24605801
Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
J Biol Chem, 290 (7), 4225-37
DOI 10.1074/jbc.M114.593962, PubMed 25519911
Raiborg C, Stenmark H (2014)
An ER clamp for endosome fission
EMBO J, 34 (2), 136-7
DOI 10.15252/embj.201490707, PubMed 25502456
Reidick C, El Magraoui F, Meyer HE, Stenmark H, Platta HW (2014)
Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
Cancers (Basel), 7 (1), 1-29
DOI 10.3390/cancers7010001, PubMed 25545884
Sagona AP, Nezis IP, Stenmark H (2014)
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
Biomed Res Int, 2014, 974393
DOI 10.1155/2014/974393, PubMed 24741567
Salvi M, Raiborg C, Hanson PI, Campsteijn C, Stenmark H, Pinna LA (2014)
CK2 involvement in ESCRT-III complex phosphorylation
Arch Biochem Biophys, 545, 83-91
DOI 10.1016/j.abb.2014.01.006, PubMed 24440309
Sandvig K, Bergan J, Kavaliauskiene S, Skotland T (2014)
Lipid requirements for entry of protein toxins into cells
Prog Lipid Res, 54, 1-13
DOI 10.1016/j.plipres.2014.01.001, PubMed 24462587
Simm R, Ahmad I, Rhen M, Le Guyon S, Römling U (2014)
Regulation of biofilm formation in Salmonella enterica serovar Typhimurium
Future Microbiol, 9 (11), 1261-82
DOI 10.2217/fmb.14.88, PubMed 25437188
Skotland T, Iversen TG, Sandvig K (2014)
Development of nanoparticles for clinical use
Nanomedicine (Lond), 9 (9), 1295-9
DOI 10.2217/nnm.14.81, PubMed 25204821
Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A (2014)
Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1)
PLoS One, 9 (3), e90687
DOI 10.1371/journal.pone.0090687, PubMed 24595027
Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K (2014)
The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol
Biochem J, 457 (3), 485-96
DOI 10.1042/BJ20130155, PubMed 24200403
Solhaug A, Torgersen ML, Holme JA, Lagadic-Gossmann D, Eriksen GS (2014)
Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol
Toxicology, 326, 119-29
DOI 10.1016/j.tox.2014.10.009, PubMed 25456271
Stiebler AC, Freitag J, Schink KO, Stehlik T, Tillmann BA, Ast J, Bölker M (2014)
Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals
PLoS Genet, 10 (10), e1004685
DOI 10.1371/journal.pgen.1004685, PubMed 25340584
Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H (2014)
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
Nat Cell Biol, 16 (6), 550-60
DOI 10.1038/ncb2959, PubMed 24814515
Wegner CS, Schink KO, Stenmark H, Brech A (2014)
Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
Methods Enzymol, 534, 3-23
DOI 10.1016/B978-0-12-397926-1.00001-9, PubMed 24359945
Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ (2014)
Antibody-mediated inhibition of ricin toxin retrograde transport
mBio, 5 (2), e00995
DOI 10.1128/mBio.00995-13, PubMed 24713323

Publications 2013

Amoasii L, Hnia K, Chicanne G, Brech A, Cowling BS, Müller MM, Schwab Y, Koebel P, Ferry A, Payrastre B, Laporte J (2013)
Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo
J Cell Sci, 126 (Pt 8), 1806-19
DOI 10.1242/jcs.118505, PubMed 23444364
Bergan J, Skotland T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2013)
The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells
PLoS One, 8 (9), e75904
DOI 10.1371/journal.pone.0075904, PubMed 24098742
Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-26
DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040
Eikenes ÅH, Brech A, Stenmark H, Haglund K (2013)
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247
Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG (2013)
Modulation of intracellular calcium homeostasis blocks autophagosome formation
Autophagy, 9 (10), 1475-90
DOI 10.4161/auto.25900, PubMed 23970164
Flinder LI, Wierød L, Rosseland CM, Huitfeldt HS, Skarpen E (2013)
FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes
J Cell Physiol, 228 (6), 1304-13
DOI 10.1002/jcp.24287, PubMed 23168795
Flåtten I, Skarstad K (2013)
The Fis protein has a stimulating role in initiation of replication in Escherichia coli in vivo
PLoS One, 8 (12), e83562
DOI 10.1371/journal.pone.0083562, PubMed 24358293
Grallert B, Boye E (2013)
GCN2, an old dog with new tricks
Biochem Soc Trans, 41 (6), 1687-91
DOI 10.1042/BST20130210, PubMed 24256275
Gregers TF, Skånland SS, Wälchli S, Bakke O, Sandvig K (2013)
BiP negatively affects ricin transport
Toxins (Basel), 5 (5), 969-82
DOI 10.3390/toxins5050969, PubMed 23666197
Haugsten EM, Oppelt A, Wesche J (2013)
Phosphatidylinositol 5-phosphate is a second messenger important for cell migration
Commun Integr Biol, 6 (5), e25446
DOI 10.4161/cib.25446, PubMed 24265857
Henne WM, Stenmark H, Emr SD (2013)
Molecular mechanisms of the membrane sculpting ESCRT pathway
Cold Spring Harb Perspect Biol, 5 (9)
DOI 10.1101/cshperspect.a016766, PubMed 24003212
Hessvik NP, Sandvig K, Llorente A (2013)
Exosomal miRNAs as Biomarkers for Prostate Cancer
Front Genet, 4, 36
DOI 10.3389/fgene.2013.00036, PubMed 23519132
Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
Autophagy, 9 (12), 1955-64
DOI 10.4161/auto.26085, PubMed 24128730
Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
Cell density-induced changes in lipid composition and intracellular trafficking
Cell Mol Life Sci, 71 (6), 1097-116
DOI 10.1007/s00018-013-1441-y, PubMed 23921715
Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
J Cell Biol, 202 (2), 331-49
DOI 10.1083/jcb.201205129, PubMed 23878278
Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
Traffic, 14 (7), 839-52
DOI 10.1111/tra.12077, PubMed 23593995
Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
Biochim Biophys Acta, 1831 (7), 1302-9
DOI 10.1016/j.bbalip.2013.04.011, PubMed 24046871
Lueke K, Kaiser T, Svetlitchny A, Welzel O, Wenzel EM, Tyagarajan S, Kornhuber J, Groemer TW (2013)
Basic presynaptic functions in hippocampal neurons are not affected by acute or chronic lithium treatment
J Neural Transm (Vienna), 121 (2), 211-9
DOI 10.1007/s00702-013-1087-9, PubMed 24036894
Nadratowska-Wesolowska B, Haugsten EM, Zakrzewska M, Jakimowicz P, Zhen Y, Pajdzik D, Wesche J, Wiedlocha A (2013)
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
Oncogene, 33 (40), 4823-36
DOI 10.1038/onc.2013.425, PubMed 24141780
O Farrell F, Rusten TE, Stenmark H (2013)
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
FEBS J, 280 (24), 6322-37
DOI 10.1111/febs.12486, PubMed 23953235
O'Farrell F, Wang S, Katheder N, Rusten TE, Samakovlis C (2013)
Two-tiered control of epithelial growth and autophagy by the insulin receptor and the ret-like receptor, stitcher
PLoS Biol, 11 (7), e1001612
DOI 10.1371/journal.pbio.1001612, PubMed 23935447
Raiborg C, Schink KO, Stenmark H (2013)
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
FEBS J, 280 (12), 2730-42
DOI 10.1111/febs.12116, PubMed 23289851
Rødland GE, Tvegård T, Boye E, Grallert B (2013)
Crosstalk between the Tor and Gcn2 pathways in response to different stresses
Cell Cycle, 13 (3), 453-61
DOI 10.4161/cc.27270, PubMed 24280780
Sandvig K, Skotland T, van Deurs B, Klokk TI (2013)
Retrograde transport of protein toxins through the Golgi apparatus
Histochem Cell Biol, 140 (3), 317-26
DOI 10.1007/s00418-013-1111-z, PubMed 23765164
Schink KO, Raiborg C, Stenmark H (2013)
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
Bioessays, 35 (10), 900-12
DOI 10.1002/bies.201300064, PubMed 23881848
Schneikert J, Vijaya Chandra SH, Ruppert JG, Ray S, Wenzel EM, Behrens J (2013)
Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation
PLoS One, 8 (7), e68072
DOI 10.1371/journal.pone.0068072, PubMed 23840886
Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
Cancer Lett, 339 (1), 25-32
DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608
Skarstad K, Katayama T (2013)
Regulating DNA replication in bacteria
Cold Spring Harb Perspect Biol, 5 (4), a012922
DOI 10.1101/cshperspect.a012922, PubMed 23471435
Slominska-Wojewodzka M, Sandvig K (2013)
Ricin and Ricin-Containing Immunotoxins: Insights into Intracellular Transport and Mechanism of action in Vitro
Antibodies, 2 (2), 236-269
DOI 10.3390/antib2020236
Solhaug A, Holme JA, Haglund K, Dendele B, Sergent O, Pestka J, Lagadic-Gossmann D, Eriksen GS (2013)
Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages
Toxicol Lett, 219 (1), 8-17
DOI 10.1016/j.toxlet.2013.02.012, PubMed 23454835
Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013)
Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
Biochim Biophys Acta, 1830 (8), 4235-43
DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966
Vörös A, Simm R, Kroeger JK, Kolstø AB (2013)
Gene transcription from the linear plasmid pBClin15 leads to cell lysis and extracellular DNA-dependent aggregation of Bacillus cereus ATCC 14579 in response to quinolone-induced stress
Microbiology (Reading), 159 (Pt 11), 2283-2293
DOI 10.1099/mic.0.069674-0, PubMed 24002748
Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
Single transmembrane peptide DinQ modulates membrane-dependent activities
PLoS Genet, 9 (2), e1003260
DOI 10.1371/journal.pgen.1003260, PubMed 23408903
Wu X, Chen JY, Brech A, Fang C, Wang J, Helm PJ, Peng Q (2013)
The use of femto-second lasers to trigger powerful explosions of gold nanorods to destroy cancer cells
Biomaterials, 34 (26), 6157-62
DOI 10.1016/j.biomaterials.2013.04.048, PubMed 23706782
Zakrzewska M, Haugsten EM, Nadratowska-Wesolowska B, Oppelt A, Hausott B, Jin Y, Otlewski J, Wesche J, Wiedlocha A (2013)
ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling
Sci Signal, 6 (262), ra11
DOI 10.1126/scisignal.2003087, PubMed 23405013

Publications 2012

Abrahamsen H, Stenmark H, Platta HW (2012)
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
FEBS Lett, 586 (11), 1584-91
DOI 10.1016/j.febslet.2012.04.046, PubMed 22673570
Becker GL, Lu Y, Hardes K, Strehlow B, Levesque C, Lindberg I, Sandvig K, Bakowsky U, Day R, Garten W, Steinmetzer T (2012)
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
J Biol Chem, 287 (26), 21992-2003
DOI 10.1074/jbc.M111.332643, PubMed 22539349
Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012)
Shiga toxins
Toxicon, 60 (6), 1085-107
DOI 10.1016/j.toxicon.2012.07.016, PubMed 22960449
Bøe CA, Knutsen JH, Boye E, Grallert B (2012)
Hpz1 modulates the G1-S transition in fission yeast
PLoS One, 7 (9), e44539
DOI 10.1371/journal.pone.0044539, PubMed 22970243
Bøe CA, Krohn M, Rødland GE, Capiaghi C, Maillard O, Thoma F, Boye E, Grallert B (2012)
Induction of a G1-S checkpoint in fission yeast
Proc Natl Acad Sci U S A, 109 (25), 9911-6
DOI 10.1073/pnas.1204901109, PubMed 22665798
Danks G, Campsteijn C, Parida M, Butcher S, Doddapaneni H, Fu B, Petrin R, Metpally R, Lenhard B, Wincker P, Chourrout D, Thompson EM, Manak JR (2012)
OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica
Nucleic Acids Res, 41 (Database issue), D845-53
DOI 10.1093/nar/gks1159, PubMed 23185044
Fingland N, Flåtten I, Downey CD, Fossum-Raunehaug S, Skarstad K, Crooke E (2012)
Depletion of acidic phospholipids influences chromosomal replication in Escherichia coli
Microbiologyopen, 1 (4), 450-66
DOI 10.1002/mbo3.46, PubMed 23233230
Haglund K, Dikic I (2012)
The role of ubiquitylation in receptor endocytosis and endosomal sorting
J Cell Sci, 125 (Pt 2), 265-75
DOI 10.1242/jcs.091280, PubMed 22357968
Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
Biochim Biophys Acta, 1819 (11-12), 1154-63
DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, Horvath P, Mancini R, Helenius A, Peter M (2012)
Cullin-3 regulates late endosome maturation
Proc Natl Acad Sci U S A, 109 (3), 823-8
DOI 10.1073/pnas.1118744109, PubMed 22219362
Ilina P, Hyvonen Z, Saura M, Sandvig K, Yliperttula M, Ruponen M (2012)
Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
J Control Release, 163 (3), 385-95
DOI 10.1016/j.jconrel.2012.09.016, PubMed 23041276
Iversen TG, Frerker N, Sandvig K (2012)
Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism
J Nanobiotechnology, 10, 33
DOI 10.1186/1477-3155-10-33, PubMed 22849338
Jha AN, Singh VK, Kumari N, Singh A, Antony J, van Tong H, Singh S, Pati SS, Patra PK, Singh R, Toan NL, Song le H, Assaf A, Messias-Reason IJ, Velavan TP, Singh L, Thangaraj K (2012)
IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations
PLoS One, 7 (10), e48136
DOI 10.1371/journal.pone.0048136, PubMed 23110190
Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK et al. (2012)
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
PLoS Biol, 10 (12), e1001450
DOI 10.1371/journal.pbio.1001450, PubMed 23271954
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2012)
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 8 (4), 445-544
DOI 10.4161/auto.19496, PubMed 22966490
Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
EMBO Rep, 14 (1), 10-1
DOI 10.1038/embor.2012.188, PubMed 23229585
Lobert VH, Stenmark H (2012)
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
J Cell Sci, 125 (Pt 1), 29-36
DOI 10.1242/jcs.088310, PubMed 22266905
Nezis IP (2012)
Selective autophagy in Drosophila
Int J Cell Biol, 2012, 146767
DOI 10.1155/2012/146767, PubMed 22567011
Nezis IP, Stenmark H (2012)
p62 at the interface of autophagy, oxidative stress signaling, and cancer
Antioxid Redox Signal, 17 (5), 786-93
DOI 10.1089/ars.2011.4394, PubMed 22074114
Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756
Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
DOI 10.1038/embor.2012.183, PubMed 23154468
Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767
Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2012)
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Biochem J, 441 (1), 399-406
DOI 10.1042/BJ20111424, PubMed 21936852
Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestøl K, Danielsen HE, van Deurs B, Sandvig K (2012)
Flotillins as regulators of ErbB2 levels in breast cancer
Oncogene, 32 (29), 3443-51
DOI 10.1038/onc.2012.357, PubMed 22869152
Sak MM, Breen K, Rønning SB, Pedersen NM, Bertelsen V, Stang E, Madshus IH (2012)
The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner
Carcinogenesis, 33 (5), 1031-9
DOI 10.1093/carcin/bgs128, PubMed 22436610
Sandvig K, Llorente A (2012)
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
Mol Cell Proteomics, 11 (7), M111.012914
DOI 10.1074/mcp.M111.012914, PubMed 22457534
Skotland T (2012)
Molecular imaging: challenges of bringing imaging of intracellular targets into common clinical use
Contrast Media Mol Imaging, 7 (1), 1-6
DOI 10.1002/cmmi.458, PubMed 22344874
Stenmark H (2012)
The Rabs: a family at the root of metazoan evolution
BMC Biol, 10, 68
DOI 10.1186/1741-7007-10-68, PubMed 22873178
Stokke C, Flåtten I, Skarstad K (2012)
An easy-to-use simulation program demonstrates variations in bacterial cell cycle parameters depending on medium and temperature
PLoS One, 7 (2), e30981
DOI 10.1371/journal.pone.0030981, PubMed 22348034
Stratford EW, Castro R, Daffinrud J, Skårn M, Lauvrak S, Munthe E, Myklebost O (2012)
Characterization of liposarcoma cell lines for preclinical and biological studies
Sarcoma, 2012, 148614
DOI 10.1155/2012/148614, PubMed 22911243
Szlachcic A, Pala K, Zakrzewska M, Jakimowicz P, Wiedlocha A, Otlewski J (2012)
FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation
Int J Nanomedicine, 7, 5915-27
DOI 10.2147/IJN.S36575, PubMed 23226697
Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN et al. (2012)
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21
Diabetes, 62 (3), 977-86
DOI 10.2337/db12-0406, PubMed 23209189
Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K (2012)
Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
PLoS One, 7 (7), e40429
DOI 10.1371/journal.pone.0040429, PubMed 22792315
Waldminghaus T, Weigel C, Skarstad K (2012)
Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome
Nucleic Acids Res, 40 (12), 5465-76
DOI 10.1093/nar/gks187, PubMed 22373925
Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Cancer Res, 72 (11), 2822-32
DOI 10.1158/0008-5472.CAN-11-3336, PubMed 22440753
Zhen Y, Sørensen V, Skjerpen CS, Haugsten EM, Jin Y, Wälchli S, Olsnes S, Wiedlocha A (2012)
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
Traffic, 13 (5), 650-64
DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063
Østerud B, Skotland T (2012)
Doping analyses are not on safe ground
Tidsskr Nor Laegeforen, 132 (8), 929-30
DOI 10.4045/tidsskr.12.0252, PubMed 22562317

Publications 2011

Abrahamsen H, Stenmark H (2011)
Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
DOI 10.1126/science.1214355, PubMed 22053037
Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD (2011)
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
Autophagy, 7 (6), 572-83
DOI 10.4161/auto.7.6.14943, PubMed 21325881
Cordara G, Egge-Jacobsen W, Johansen HT, Winter HC, Goldstein IJ, Sandvig K, Krengel U (2011)
Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
Biochem Biophys Res Commun, 408 (3), 405-10
DOI 10.1016/j.bbrc.2011.04.031, PubMed 21513701
Dang H, Klokk TI, Schaheen B, McLaughlin BM, Thomas AJ, Durns TA, Bitler BG, Sandvig K, Fares H (2011)
Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
Traffic, 12 (10), 1417-31
DOI 10.1111/j.1600-0854.2011.01243.x, PubMed 21722281
Dyve Lingelem AB, Bergan J, Sandvig K (2011)
Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
Traffic, 13 (3), 443-54
DOI 10.1111/j.1600-0854.2011.01319.x, PubMed 22132807
Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
Shiga toxin and its use in targeted cancer therapy and imaging
Microb Biotechnol, 4 (1), 32-46
DOI 10.1111/j.1751-7915.2010.00180.x, PubMed 21255370
Eskelinen EL, Reggiori F, Baba M, Kovács AL, Seglen PO (2011)
Seeing is believing: the impact of electron microscopy on autophagy research
Autophagy, 7 (9), 935-56
DOI 10.4161/auto.7.9.15760, PubMed 21566462
Freitag J, Lanver D, Böhmer C, Schink KO, Bölker M, Sandrock B (2011)
Septation of infectious hyphae is critical for appressoria formation and virulence in the smut fungus Ustilago maydis
PLoS Pathog, 7 (5), e1002044
DOI 10.1371/journal.ppat.1002044, PubMed 21625538
George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH (2011)
Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation
J Biol Chem, 287 (7), 5042-58
DOI 10.1074/jbc.M111.308916, PubMed 22184107
Grimm I, Saffian D, Platta HW, Erdmann R (2011)
The AAA-type ATPases Pex1p and Pex6p and their role in peroxisomal matrix protein import in Saccharomyces cerevisiae
Biochim Biophys Acta, 1823 (1), 150-8
DOI 10.1016/j.bbamcr.2011.09.005, PubMed 21963882
Grunau S, Lay D, Mindthoff S, Platta HW, Girzalsky W, Just WW, Erdmann R (2011)
The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae
Biochem J, 434 (1), 161-70
DOI 10.1042/BJ20101115, PubMed 21121900
Haglund K, Nezis IP, Stenmark H (2011)
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
DOI 10.4161/cib.4.1.13550, PubMed 21509167
Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
PLoS One, 6 (7), e21708
DOI 10.1371/journal.pone.0021708, PubMed 21779335
Hausott B, Vallant N, Hochfilzer M, Mangger S, Irschick R, Haugsten EM, Klimaschewski L (2011)
Leupeptin enhances cell surface localization of fibroblast growth factor receptor 1 in adult sensory neurons by increased recycling
Eur J Cell Biol, 91 (2), 129-38
DOI 10.1016/j.ejcb.2011.09.009, PubMed 22169219
Helmrich U, Marsano A, Melly L, Wolff T, Christ L, Heberer M, Scherberich A, Martin I, Banfi A (2011)
Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification
Tissue Eng Part C Methods, 18 (4), 283-92
DOI 10.1089/ten.TEC.2011.0413, PubMed 22070632
Hurley JH, Stenmark H (2011)
Molecular mechanisms of ubiquitin-dependent membrane traffic
Annu Rev Biophys, 40, 119-42
DOI 10.1146/annurev-biophys-042910-155404, PubMed 21332354
Iversen TG (2011)
Nanoparticles hinder intracellular transport
Trac-Trends Anal. Chem., 30 (10), VII-VIII
Iversen TG, Skotland T, Sandvig K (2011)
Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
Nano Today, 6 (2), 176-185
DOI 10.1016/j.nantod.2011.02.003
Jin Y, Zhen Y, Haugsten EM, Wiedlocha A (2011)
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
Cell Signal, 23 (11), 1758-66
DOI 10.1016/j.cellsig.2011.06.010, PubMed 21745565
Johnsen E, Wilson SR, Odsbu I, Krapp A, Malerod H, Skarstad K, Lundanes E (2011)
Hydrophilic interaction chromatography of nucleoside triphosphates with temperature as a separation parameter
J Chromatogr A, 1218 (35), 5981-6
DOI 10.1016/j.chroma.2011.01.066, PubMed 21315360
Klokk TI, Lingelem AB, Myrann AG, Sandvig K (2011)
Role of phospholipase A(2) in retrograde transport of ricin
Toxins (Basel), 3 (9), 1203-19
DOI 10.3390/toxins3091203, PubMed 22069763
Knutsen JH, Rein ID, Rothe C, Stokke T, Grallert B, Boye E (2011)
Cell-cycle analysis of fission yeast cells by flow cytometry
PLoS One, 6 (2), e17175
DOI 10.1371/journal.pone.0017175, PubMed 21386895
Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
DOI 10.1038/onc.2011.109, PubMed 21499309
Lobert VH, Stenmark H (2011)
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda), 26 (3), 171-80
DOI 10.1152/physiol.00054.2010, PubMed 21670163
Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
DOI 10.1111/j.1600-0854.2011.01220.x, PubMed 21564451
Martinez AL, Roxrud I (2011)
Basic and discovery-based translational research on cancer was on the agenda at the 21st Congress of the European Association for Cancer Research (EACR) in Oslo, Norway, 26-29 June 2010
Clin. Transl. Oncol., 13 (1), 1-2
DOI 10.1007/s12094-011-0608-y
Moosmann A, Campsteijn C, Jansen PW, Nasrallah C, Raasholm M, Stunnenberg HG, Thompson EM (2011)
Histone variant innovation in a rapidly evolving chordate lineage
BMC Evol Biol, 11, 208
DOI 10.1186/1471-2148-11-208, PubMed 21756361
Platta HW, Stenmark H (2011)
Endocytosis and signaling
Curr Opin Cell Biol, 23 (4), 393-403
DOI 10.1016/j.ceb.2011.03.008, PubMed 21474295
Raiborg C, Stenmark H (2011)
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
DOI 10.1126/science.1204208, PubMed 21436431
Rusten TE, Vaccari T, Stenmark H (2011)
Shaping development with ESCRTs
Nat Cell Biol, 14 (1), 38-45
DOI 10.1038/ncb2381, PubMed 22193162
Rønning SB, Pedersen NM, Madshus IH, Stang E (2011)
CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
Exp Cell Res, 317 (13), 1804-16
DOI 10.1016/j.yexcr.2011.05.016, PubMed 21635887
Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
DOI 10.1371/journal.pone.0017086, PubMed 21455500
Sandvig K, Pust S, Skotland T, van Deurs B (2011)
Clathrin-independent endocytosis: mechanisms and function
Curr Opin Cell Biol, 23 (4), 413-20
DOI 10.1016/j.ceb.2011.03.007, PubMed 21466956
Schink KO, Stenmark H (2011)
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
DOI 10.1016/j.cub.2011.10.035, PubMed 22153165
Shahzidi S, Cunderlíková B, Więdłocha A, Zhen Y, Vasovič V, Nesland JM, Peng Q (2011)
Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells
Photochem Photobiol Sci, 10 (11), 1773-82
DOI 10.1039/c1pp05169e, PubMed 21881674
Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2011)
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int J Cancer, 131 (3), 570-81
DOI 10.1002/ijc.26392, PubMed 21866551
Skotland T, Iversen TG, Sandvig K (2011)
Comment on "short ligands affect modes of QD uptake and elimination in human cells"
ACS Nano, 5 (10), 7690; author reply 7691-2
DOI 10.1021/nn2021953, PubMed 22023400
Sokołowska I, Wälchli S, Węgrzyn G, Sandvig K, Słomińska-Wojewódzka M (2011)
A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
Biochem J, 436 (2), 371-85
DOI 10.1042/BJ20101493, PubMed 21388347
Stenmark H (2011)
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
DOI 10.1083/jcb.1924pi, PubMed 21339328
Stratford EW, Castro R, Wennerstrom A, Holm R, Munthe E, Lauvrak S, Bjerkehagen B, Myklebost O (2011)
Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
Clin Sarcoma Res, 1 (1), 8
DOI 10.1186/2045-3329-1-8, PubMed 22612877
Takahashi Y, Shimokawa N, Esmaeili-Mahani S, Morita A, Masuda H, Iwasaki T, Tamura J, Haglund K, Koibuchi N (2011)
Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
FEBS Lett, 585 (12), 1741-7
DOI 10.1016/j.febslet.2011.04.056, PubMed 21570973
Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2011)
Protein C mutation (A267T) results in ER retention and unfolded protein response activation
PLoS One, 6 (8), e24009
DOI 10.1371/journal.pone.0024009, PubMed 21901152
Ugland H, Naderi S, Brech A, Collas P, Blomhoff HK (2011)
cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
Autophagy, 7 (10), 1199-211
DOI 10.4161/auto.7.10.16649, PubMed 21750416
Warsame AA, Aasheim HC, Nustad K, Trøen G, Tierens A, Wang V, Randen U, Dong HP, Heim S, Brech A, Delabie J (2011)
Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
Blood, 118 (12), 3331-9
DOI 10.1182/blood-2011-03-341651, PubMed 21725051
Wegner CS, Rodahl LM, Stenmark H (2011)
ESCRT proteins and cell signalling
Traffic, 12 (10), 1291-7
DOI 10.1111/j.1600-0854.2011.01210.x, PubMed 21518165
Wesche J, Haglund K, Haugsten EM (2011)
Fibroblast growth factors and their receptors in cancer
Biochem J, 437 (2), 199-213
DOI 10.1042/BJ20101603, PubMed 21711248
Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966
Øverbye A, Sætre F, Hagen LK, Johansen HT, Seglen PO (2011)
Autophagic activity measured in whole rat hepatocytes as the accumulation of a novel BHMT fragment (p10), generated in amphisomes by the asparaginyl proteinase, legumain
Autophagy, 7 (9), 1011-27
DOI 10.4161/auto.7.9.16436, PubMed 21610319

Publications 2010

Abrahamsen H, Stenmark H (2010)
Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
DOI 10.1016/j.cub.2010.03.011, PubMed 20462486
Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
DOI 10.4161/auto.6.3.11226, PubMed 20168092
Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
DOI 10.1016/j.molcel.2010.04.007, PubMed 20417604
Groves B, Abrahamsen H, Clingan H, Frantz M, Mavor L, Bailey J, Ma D (2010)
An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
PLoS One, 5 (1), e8877
DOI 10.1371/journal.pone.0008877, PubMed 20126274
Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
DOI 10.1016/j.cub.2010.03.068, PubMed 20451383
Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH (2010)
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
J Infect Dis, 201 (5), 783-92
DOI 10.1086/650493, PubMed 20121435
Haugsten EM, Wiedlocha A, Olsnes S, Wesche J (2010)
Roles of fibroblast growth factor receptors in carcinogenesis
Mol Cancer Res, 8 (11), 1439-52
DOI 10.1158/1541-7786.MCR-10-0168, PubMed 21047773
Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Immunity, 33 (4), 583-96
DOI 10.1016/j.immuni.2010.09.010, PubMed 20933442
Johnsen L, Flåtten I, Morigen, Dalhus B, Bjørås M, Waldminghaus T, Skarstad K (2010)
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
Mol Microbiol, 79 (2), 433-46
DOI 10.1111/j.1365-2958.2010.07453.x, PubMed 21219462
Johnsen L, Weigel C, von Kries J, Møller M, Skarstad K (2010)
A novel DNA gyrase inhibitor rescues Escherichia coli dnaAcos mutant cells from lethal hyperinitiation
J Antimicrob Chemother, 65 (5), 924-30
DOI 10.1093/jac/dkq071, PubMed 20228083
Klionsky DJ, Seglen PO (2010)
The Norse god of autophagy. Interviewed by Daniel J Klionsky
Autophagy, 6 (8), 1017-31
DOI 10.4161/auto.6.8.13092, PubMed 20814236
Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
DOI 10.4161/auto.6.7.13033, PubMed 20724836
Landsverk OJ, Barois N, Gregers TF, Bakke O (2010)
Invariant chain increases the half-life of MHC II by delaying endosomal maturation
Immunol Cell Biol, 89 (5), 619-29
DOI 10.1038/icb.2010.143, PubMed 21116285
Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
DOI 10.1016/j.devcel.2010.06.010, PubMed 20643357
Lobert VH, Stenmark H (2010)
Ubiquitination of α-integrin cytoplasmic tails
Commun Integr Biol, 3 (6), 583-5
DOI 10.4161/cib.3.6.13176, PubMed 21331246
Malagoli D, Abdalla FC, Cao Y, Feng Q, Fujisaki K, Gregorc A, Matsuo T, Nezis IP, Papassideri IS, Sass M, Silva-Zacarin EC, Tettamanti G, Umemiya-Shirafuji R (2010)
Autophagy and its physiological relevance in arthropods: current knowledge and perspectives
Autophagy, 6 (5), 575-88
DOI 10.4161/auto.6.5.11962, PubMed 20458176
Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
DOI 10.1016/j.tcb.2010.08.010, PubMed 20880709
Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-+
DOI 10.4161/auto.6.8.13694
Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
DOI 10.4161/auto.6.8.13694, PubMed 20935512
Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
DOI 10.1083/jcb.201002035, PubMed 20713604
Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010)
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
J Cell Biol, 188 (2), 253-69
DOI 10.1083/jcb.200907015, PubMed 20100911
Pust S, Barth H, Sandvig K (2010)
Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
Cell Microbiol, 12 (12), 1809-20
DOI 10.1111/j.1462-5822.2010.01512.x, PubMed 20690924
Pust S, Dyve AB, Torgersen ML, van Deurs B, Sandvig K (2010)
Interplay between toxin transport and flotillin localization
PLoS One, 5 (1), e8844
DOI 10.1371/journal.pone.0008844, PubMed 20107503
Roxrud I, Stenmark H, Malerød L (2010)
ESCRT & Co
Biol Cell, 102 (5), 293-318
DOI 10.1042/BC20090161, PubMed 20222872
Rusten TE, Stenmark H (2010)
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
DOI 10.1038/ncb0310-207, PubMed 20190829
Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
DOI 10.1038/ncb2036, PubMed 20208530
Sagona AP, Stenmark H (2010)
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128
DOI 10.1016/j.febslet.2010.08.016
Sagona AP, Stenmark H (2010)
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
DOI 10.1016/j.febslet.2010.03.044, PubMed 20371245
Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
FEBS Lett, 584 (12), 2626-34
DOI 10.1016/j.febslet.2010.04.008, PubMed 20385131
Seglen PO, Brinchmann MF (2010)
Purification of autophagosomes from rat hepatocytes
Autophagy, 6 (4), 542-7
DOI 10.4161/auto.6.4.11272, PubMed 20505360
Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MHH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O et al. (2010)
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
EMBO J, 29 (14), 2421-32
DOI 10.1038/emboj.2010.120, PubMed 20551902
Skotland T, Iversen TG, Sandvig K (2010)
New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
Nanomedicine, 6 (6), 730-7
DOI 10.1016/j.nano.2010.05.002, PubMed 20570639
Stokke C, Waldminghaus T, Skarstad K (2010)
Replication patterns and organization of replication forks in Vibrio cholerae
Microbiology (Reading), 157 (Pt 3), 695-708
DOI 10.1099/mic.0.045112-0, PubMed 21163839
Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
J Histochem Cytochem, 58 (11), 1025-32
DOI 10.1369/jhc.2010.955815, PubMed 20713985
Teichmann B, Liu L, Schink KO, Bölker M (2010)
Activation of the ustilagic acid biosynthesis gene cluster in Ustilago maydis by the C2H2 zinc finger transcription factor Rua1
Appl Environ Microbiol, 76 (8), 2633-40
DOI 10.1128/AEM.02211-09, PubMed 20173069
Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
DOI 10.1016/j.yexcr.2010.07.008, PubMed 20643123
Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2010)
Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
BMC Cell Biol, 11, 67
DOI 10.1186/1471-2121-11-67, PubMed 20815936
Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
The Intracellular Journey of Shiga Toxins
The Open Toxinology Journal, 3, 3-12
PublikaID 24
Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
FEMS Immunol Med Microbiol, 61 (1), 63-75
DOI 10.1111/j.1574-695X.2010.00749.x, PubMed 21054580
Utskarpen A, Massol R, van Deurs B, Lauvrak SU, Kirchhausen T, Sandvig K (2010)
Shiga toxin increases formation of clathrin-coated pits through Syk kinase
PLoS One, 5 (7), e10944
DOI 10.1371/journal.pone.0010944, PubMed 20668539
Waldminghaus T, Skarstad K (2010)
ChIP on Chip: surprising results are often artifacts
BMC Genomics, 11, 414
DOI 10.1186/1471-2164-11-414, PubMed 20602746

Publications 2009

Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T (2009)
Monitoring autophagic degradation of p62/SQSTM1
Methods Enzymol, 452, 181-97
DOI 10.1016/S0076-6879(08)03612-4, PubMed 19200883
Boeneman K, Fossum S, Yang Y, Fingland N, Skarstad K, Crooke E (2009)
Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments
Mol Microbiol, 72 (3), 645-57
DOI 10.1111/j.1365-2958.2009.06674.x, PubMed 19400775
Boye E, Grallert B (2009)
In DNA replication, the early bird catches the worm
Cell, 136 (5), 812-4
DOI 10.1016/j.cell.2009.02.023, PubMed 19269359
Boye E, Skjølberg HC, Grallert B (2009)
Checkpoint regulation of DNA replication
Methods Mol Biol, 521, 55-70
DOI 10.1007/978-1-60327-815-7_4, PubMed 19563101
Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660
Dyve AB, Bergan J, Utskarpen A, Sandvig K (2009)
Sorting nexin 8 regulates endosome-to-Golgi transport
Biochem Biophys Res Commun, 390 (1), 109-14
DOI 10.1016/j.bbrc.2009.09.076, PubMed 19782049
Døving KB, Sandvig K, Kasumyan A (2009)
Ligand-specific induction of endocytosis in taste receptor cells
J Exp Biol, 212 (Pt 1), 42-9
DOI 10.1242/jeb.025700, PubMed 19088209
Iversen TG, Frerker N, Sandvig K (2009)
Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
PublikaID 29
Kaiser E, Pust S, Kroll C, Barth H (2009)
Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells
Cell Microbiol, 11 (5), 780-95
DOI 10.1111/j.1462-5822.2009.01291.x, PubMed 19159389
Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
DOI 10.1242/jcs.053801, PubMed 19808888
Malerød L, Stenmark H (2009)
ESCRTing membrane deformation
Cell, 136 (1), 15-7
DOI 10.1016/j.cell.2008.12.029, PubMed 19135881
Morigen, Odsbu I, Skarstad K (2009)
Growth rate dependent numbers of SeqA structures organize the multiple replication forks in rapidly growing Escherichia coli
Genes Cells, 14 (5), 643-57
DOI 10.1111/j.1365-2443.2009.01298.x, PubMed 19371375
Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
DOI 10.4161/auto.5.3.7454, PubMed 19066465
Odsbu I, Morigen, Skarstad K (2009)
A reduction in ribonucleotide reductase activity slows down the chromosome replication fork but does not change its localization
PLoS One, 4 (10), e7617
DOI 10.1371/journal.pone.0007617, PubMed 19898675
Raiborg C, Stenmark H (2009)
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
DOI 10.1038/nature07961, PubMed 19325624
Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
DOI 10.1371/journal.pone.0004354, PubMed 19194501
Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
DOI 10.1042/BST0370137, PubMed 19143618
Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
DOI 10.1016/j.yexcr.2009.07.012, PubMed 19619532
Rusten TE, Stenmark H (2009)
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
DOI 10.1242/jcs.050021, PubMed 19535733
Raa H, Grimmer S, Schwudke D, Bergan J, Wälchli S, Skotland T, Shevchenko A, Sandvig K (2009)
Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
Traffic, 10 (7), 868-82
DOI 10.1111/j.1600-0854.2009.00919.x, PubMed 19453975
Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
Endocytosis and retrograde transport of Shiga toxin
Toxicon, 56 (7), 1181-5
DOI 10.1016/j.toxicon.2009.11.021, PubMed 19951719
Seglen PO, Øverbye A, Saetre F (2009)
Sequestration assays for mammalian autophagy
Methods Enzymol, 452, 63-83
DOI 10.1016/S0076-6879(08)03605-7, PubMed 19200876
Skjølberg HC, Fensgård O, Nilsen H, Grallert B, Boye E (2009)
Global transcriptional response after exposure of fission yeast cells to ultraviolet light
BMC Cell Biol, 10, 87
DOI 10.1186/1471-2121-10-87, PubMed 20015352
Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
DOI 10.1371/journal.pone.0005935, PubMed 19529763
Skånland SS, Wälchli S, Sandvig K (2009)
β-arrestins attenuate p38-mediated endosome to Golgi transport
Cell Microbiol, 11 (5), 796-807
DOI 10.1111/j.1462-5822.2009.01292.x, PubMed 19159388
Stenmark H (2009)
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
DOI 10.1038/nrm2728, PubMed 19603039
Stenmark H (2009)
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
DOI 10.1038/nrm2747, PubMed 19702012
Stepankiw N, Kaidow A, Boye E, Bates D (2009)
The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication
Mol Microbiol, 74 (2), 467-79
DOI 10.1111/j.1365-2958.2009.06877.x, PubMed 19737351
Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
DOI 10.1111/j.1600-0854.2009.00920.x, PubMed 19490536
Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
DOI 10.1242/jcs.046391, PubMed 19571114
Waldminghaus T, Skarstad K (2009)
The Escherichia coli SeqA protein
Plasmid, 61 (3), 141-50
DOI 10.1016/j.plasmid.2009.02.004, PubMed 19254745
Wang J, Morigen (2009)
BayesPI - a new model to study protein-DNA interactions: a case study of condition-specific protein binding parameters for Yeast transcription factors
BMC Bioinformatics, 10, 345
DOI 10.1186/1471-2105-10-345, PubMed 19857274
Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
DOI 10.1007/s00418-009-0643-8, PubMed 19830447
Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
Characterization of clathrin and Syk interaction upon Shiga toxin binding
Cell Signal, 21 (7), 1161-8
DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168
Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S (2009)
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
J Biol Chem, 284 (37), 25388-403
DOI 10.1074/jbc.M109.001289, PubMed 19574212
Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J (2009)
Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
Biochemistry, 48 (30), 7209-18
DOI 10.1021/bi9007353, PubMed 19558187
Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH (2009)
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
J Immunol, 183 (9), 5909-16
DOI 10.4049/jimmunol.0900441, PubMed 19812211
Øverbye A, Seglen PO (2009)
Phosphorylated and non-phosphorylated forms of catechol O-methyltransferase in rat liver, brain and other tissues
Biochem J, 417 (2), 535-45
DOI 10.1042/BJ20081284, PubMed 18831714

Publications 2008

Bach T, Morigen, Skarstad K (2008)
The initiator protein DnaA contributes to keeping new origins inactivated by promoting the presence of hemimethylated DNA
J Mol Biol, 384 (5), 1076-85
DOI 10.1016/j.jmb.2008.09.042, PubMed 18835566
Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
DOI 10.1038/sj.embor.7401152, PubMed 18188183
Bøe CA, Garcia I, Pai CC, Sharom JR, Skjølberg HC, Boye E, Kearsey S, Macneill SA, Tyers MD, Grallert B (2008)
Rapid regulation of protein activity in fission yeast
BMC Cell Biol, 9, 23
DOI 10.1186/1471-2121-9-23, PubMed 18457584
Cumming RC, Simonsen A, Finley KD (2008)
Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
Methods Enzymol, 451, 639-51
DOI 10.1016/S0076-6879(08)03235-7, PubMed 19185743
Engedal N, Auberger P, Blomhoff HK (2008)
Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly
J Leukoc Biol, 85 (3), 469-80
DOI 10.1189/jlb.1107790, PubMed 19112091
Flåtten I, Morigen, Skarstad K (2008)
DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin
Mol Microbiol, 71 (4), 1018-30
DOI 10.1111/j.1365-2958.2008.06585.x, PubMed 19170875
Fossum S, De Pascale G, Weigel C, Messer W, Donadio S, Skarstad K (2008)
A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication
FEMS Microbiol Lett, 281 (2), 210-4
DOI 10.1111/j.1574-6968.2008.01103.x, PubMed 18312360
Fuller RS (2008)
A tribute to Arthur Kornberg 1918-2007
Nat Struct Mol Biol, 15 (1), 2-17
DOI 10.1038/nsmb0108-2, PubMed 18176549
Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
DOI 10.1016/j.ajhg.2008.01.013, PubMed 18342287
Grallert B, Boye E (2008)
The multiple facets of the intra-S checkpoint
Cell Cycle, 7 (15), 2315-20
DOI 10.4161/cc.6389, PubMed 18677104
Grosso S, Volta V, Sala LA, Vietri M, Marchisio PC, Ron D, Biffo S (2008)
PKCbetaII modulates translation independently from mTOR and through RACK1
Biochem J, 415 (1), 77-85
DOI 10.1042/BJ20080463, PubMed 18557705
Grosso S, Volta V, Vietri M, Gorrini C, Marchisio PC, Biffo S (2008)
Eukaryotic ribosomes host PKC activity
Biochem Biophys Res Commun, 376 (1), 65-9
DOI 10.1016/j.bbrc.2008.08.118, PubMed 18768137
Haugsten EM, Malecki J, Bjørklund SM, Olsnes S, Wesche J (2008)
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
Mol Biol Cell, 19 (8), 3390-403
DOI 10.1091/mbc.e07-12-1219, PubMed 18480409
Heine K, Pust S, Enzenmüller S, Barth H (2008)
ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death
Infect Immun, 76 (10), 4600-8
DOI 10.1128/IAI.00651-08, PubMed 18710868
Klionsky DJ, Elazar Z, Seglen PO, Rubinsztein DC (2008)
Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
Autophagy, 4 (7), 849-50
DOI 10.4161/auto.6845, PubMed 18758232
Krohn M, Skjølberg HC, Soltani H, Grallert B, Boye E (2008)
The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint
J Cell Sci, 121 (Pt 24), 4047-54
DOI 10.1242/jcs.035428, PubMed 19033384
Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
DOI 10.4161/auto.5829, PubMed 18326940
Miaczynska M, Stenmark H (2008)
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
DOI 10.1083/jcb.200711073, PubMed 18195098
Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
DOI 10.1091/mbc.e08-07-0716, PubMed 18685079
Nezis IP, Papassideri I (2008)
Monitoring autophagy in insect eggs
Methods Enzymol, 451, 669-83
DOI 10.1016/S0076-6879(08)03237-0, PubMed 19185745
Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
DOI 10.1083/jcb.200711108, PubMed 18347073
Raposo G, Stenmark H (2008)
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
DOI 10.1016/j.ceb.2008.06.005, PubMed 18588977
Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236
DOI 10.4161/auto.5396
Rusten TE, Simonsen A (2008)
ESCRT functions in autophagy and associated disease
Cell Cycle, 7 (9), 1166-72
DOI 10.4161/cc.7.9.5784, PubMed 18418046
Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
Histochem Cell Biol, 129 (3), 267-76
DOI 10.1007/s00418-007-0376-5, PubMed 18193449
Sandvig K, van Deurs B (2008)
Cell biology: Viruses in camouflage
Nature, 453 (7194), 466-7
DOI 10.1038/453466a, PubMed 18497813
Simonsen A, Stenmark H (2008)
Self-eating from an ER-associated cup
J Cell Biol, 182 (4), 621-2
DOI 10.1083/jcb.200807061, PubMed 18725534
Stuffers S, Brech A, Stenmark H (2008)
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
DOI 10.1016/j.yexcr.2008.10.013, PubMed 19013455
Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
DOI 10.1128/MCB.02117-07, PubMed 18411303
Tekle C, Deurs Bv, Sandvig K, Iversen TG (2008)
Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
Nano Lett, 8 (7), 1858-65
DOI 10.1021/nl0803848, PubMed 18570482
Umebayashi K, Stenmark H, Yoshimori T (2008)
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
DOI 10.1091/mbc.e07-10-0988, PubMed 18508924
Zakrzewska M, Marcinkowska E, Wiedlocha A (2008)
FGF-1: from biology through engineering to potential medical applications
Crit Rev Clin Lab Sci, 45 (1), 91-135
DOI 10.1080/10408360701713120, PubMed 18293181

Publications 2007

Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH (2007)
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
Exp Cell Res, 313 (8), 1696-709
DOI 10.1016/j.yexcr.2007.02.017, PubMed 17382318
Citores L, Bai L, Sørensen V, Olsnes S (2007)
Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
J Cell Physiol, 212 (1), 148-56
DOI 10.1002/jcp.21014, PubMed 17311277
Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
DOI 10.1016/j.biochi.2006.12.012, PubMed 17335953
Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
DOI 10.1083/jcb.200702115, PubMed 17984323
Fort J, de la Ballina LR, Burghardt HE, Ferrer-Costa C, Turnay J, Ferrer-Orta C, Usón I, Zorzano A, Fernández-Recio J, Orozco M, Lizarbe MA, Fita I, Palacín M (2007)
The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane
J Biol Chem, 282 (43), 31444-52
DOI 10.1074/jbc.M704524200, PubMed 17724034
Fossum S, Crooke E, Skarstad K (2007)
Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli
EMBO J, 26 (21), 4514-22
DOI 10.1038/sj.emboj.7601871, PubMed 17914458
Grallert B, Boye E (2007)
The Gcn2 kinase as a cell cycle regulator
Cell Cycle, 6 (22), 2768-72
DOI 10.4161/cc.6.22.4933, PubMed 17986863
Haglund K, Rusten TE, Stenmark H (2007)
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217
Hughes T, Rusten TE (2007)
Origin and evolution of self-consumption: autophagy
Adv Exp Med Biol, 607, 111-8
DOI 10.1007/978-0-387-74021-8_9, PubMed 17977463
Klionsky DJ, Cuervo AM, Dunn WA, Levine B, van der Klei I, Seglen PO (2007)
How shall I eat thee?
Autophagy, 3 (5), 413-6
DOI 10.4161/auto.4377, PubMed 17568180
Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
Llorente A, van Deurs B, Sandvig K (2007)
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
Eur J Cell Biol, 86 (7), 405-15
DOI 10.1016/j.ejcb.2007.05.001, PubMed 17601634
Malerød L, Stenmark H (2007)
ESCRTs
Curr Biol, 17 (2), R42-3
DOI 10.1016/j.cub.2006.12.009, PubMed 17240322
Malerød L, Stuffers S, Brech A, Stenmark H (2007)
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
DOI 10.1111/j.1600-0854.2007.00630.x, PubMed 17714434
Martín-Acebes MA, González-Magaldi M, Sandvig K, Sobrino F, Armas-Portela R (2007)
Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
Virology, 369 (1), 105-18
DOI 10.1016/j.virol.2007.07.021, PubMed 17714753
Nilsen T, Rosendal KR, Sørensen V, Wesche J, Olsnes S, Wiedłocha A (2007)
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
J Biol Chem, 282 (36), 26245-56
DOI 10.1074/jbc.M611234200, PubMed 17616529
Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K (2007)
Functional taxonomy of bacterial hyperstructures
Microbiol Mol Biol Rev, 71 (1), 230-53
DOI 10.1128/MMBR.00035-06, PubMed 17347523
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
J Biol Chem, 282 (33), 24131-45
DOI 10.1074/jbc.M702824200, PubMed 17580304
Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
DOI 10.1242/jcs.017301, PubMed 17959629
Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739
Rusten TE, Stenmark H (2007)
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
DOI 10.1038/445497a, PubMed 17268460
Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
DOI 10.1016/j.cub.2007.09.032, PubMed 17935992
Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2007)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Autophagy, 4 (2), 176-84
DOI 10.4161/auto.5269, PubMed 18059160
Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD (2007)
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
Genetics, 176 (2), 1283-97
DOI 10.1534/genetics.106.065011, PubMed 17435236
Simonsen A, Stenmark H (2007)
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
DOI 10.1038/nchembio0607-304, PubMed 17510644
Skånland SS, Wälchli S, Utskarpen A, Wandinger-Ness A, Sandvig K (2007)
Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
Traffic, 8 (3), 297-309
DOI 10.1111/j.1600-0854.2006.00527.x, PubMed 17319803
Spilsberg B, Llorente A, Sandvig K (2007)
Polyunsaturated fatty acids regulate Shiga toxin transport
Biochem Biophys Res Commun, 364 (2), 283-8
DOI 10.1016/j.bbrc.2007.09.126, PubMed 17942073
Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
J Biol Chem, 282 (22), 16317-28
DOI 10.1074/jbc.M610886200, PubMed 17403690
Tvegård T, Soltani H, Skjølberg HC, Krohn M, Nilssen EA, Kearsey SE, Grallert B, Boye E (2007)
A novel checkpoint mechanism regulating the G1/S transition
Genes Dev, 21 (6), 649-54
DOI 10.1101/gad.421807, PubMed 17369398
Utskarpen A, Slagsvold HH, Dyve AB, Skånland SS, Sandvig K (2007)
SNX1 and SNX2 mediate retrograde transport of Shiga toxin
Biochem Biophys Res Commun, 358 (2), 566-70
DOI 10.1016/j.bbrc.2007.04.159, PubMed 17498660
Zhen Y, Sørensen V, Jin Y, Suo Z, Wiedłocha A (2007)
Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
Oncogene, 26 (44), 6372-85
DOI 10.1038/sj.onc.1210473, PubMed 17533378
Øverbye A, Fengsrud M, Seglen PO (2007)
Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
Autophagy, 3 (4), 300-22
DOI 10.4161/auto.3910, PubMed 17377489

Publications 2006

Bache KG (2006)
The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
DOI 10.1615/critrevoncog.v12.i3-4.90, PubMed 17425510
Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
DOI 10.1091/mbc.e05-10-0915, PubMed 16554368
Boye E (2006)
DisA, a busy bee that monitors chromosome integrity
Cell, 125 (4), 641-3
DOI 10.1016/j.cell.2006.05.004, PubMed 16713555
Cabezas A, Pattni K, Stenmark H (2006)
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
DOI 10.1016/j.gene.2005.11.009, PubMed 16448788
Gon S, Camara JE, Klungsøyr HK, Crooke E, Skarstad K, Beckwith J (2006)
A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli
EMBO J, 25 (5), 1137-47
DOI 10.1038/sj.emboj.7600990, PubMed 16482221
Grimmer S, Spilsberg B, Hanada K, Sandvig K (2006)
Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
Traffic, 7 (9), 1243-53
DOI 10.1111/j.1600-0854.2006.00456.x, PubMed 16919154
Haglund K, Stenmark H (2006)
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
DOI 10.1038/ncb1106-1218, PubMed 17077855
Hecker CM, Rabiller M, Haglund K, Bayer P, Dikic I (2006)
Specification of SUMO1- and SUMO2-interacting motifs
J Biol Chem, 281 (23), 16117-27
DOI 10.1074/jbc.M512757200, PubMed 16524884
Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
DOI 10.1038/nsmb1051, PubMed 16462748
Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
DOI 10.1038/nsmb1163, PubMed 17057714
Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
DOI 10.1038/ncb1354, PubMed 16429130
Hollås H, Aukrust I, Grimmer S, Strand E, Flatmark T, Vedeler A (2006)
Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA
Biochim Biophys Acta, 1763 (11), 1325-34
DOI 10.1016/j.bbamcr.2006.08.043, PubMed 17045350
Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
DOI 10.1038/sj.emboj.7600991, PubMed 16467847
Huynh T, Wälchli S, Sioud M (2006)
Transcriptional targeting of small interfering RNAs into cancer cells
Biochem Biophys Res Commun, 350 (4), 854-9
DOI 10.1016/j.bbrc.2006.09.127, PubMed 17034763
Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006)
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
Mol Cell Biol, 26 (2), 389-401
DOI 10.1128/MCB.26.2.389-401.2006, PubMed 16382132
Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH (2006)
EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
Traffic, 7 (11), 1518-27
DOI 10.1111/j.1600-0854.2006.00487.x, PubMed 16984407
Khnykin D, Olsnes S (2006)
Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
Growth Factors, 24 (2), 111-9
DOI 10.1080/08977190600621388, PubMed 16801131
Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T, Chang CY, Hager GL, Saatcioglu F (2006)
Ligand-specific dynamics of the androgen receptor at its response element in living cells
Mol Cell Biol, 27 (5), 1823-43
DOI 10.1128/MCB.01297-06, PubMed 17189428
Leithe E, Brech A, Rivedal E (2006)
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
DOI 10.1042/BJ20050674, PubMed 16162097
Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212
Lindmo K, Stenmark H (2006)
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
DOI 10.1242/jcs.02855, PubMed 16467569
Lindmo K, Stenmark H (2006)
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
DOI 10.4161/auto.3091, PubMed 16874068
Marcinkowska E, Superat K, Wiedłocha A (2006)
FGF-1 as a possible carrier for targeted drug delivery
Oncol Res, 16 (1), 27-34
DOI 10.3727/000000006783981242, PubMed 16783965
Michaelsen TE, Thommesen JE, Ihle O, Gregers TF, Sandin RH, Brekke OH, Sandlie I (2006)
A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells
Eur J Immunol, 36 (1), 129-38
DOI 10.1002/eji.200535178, PubMed 16323243
Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
DOI 10.1016/j.yexcr.2006.06.004, PubMed 16859684
Norlén L, Gil IP, Simonsen A, Descouts P (2006)
Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
J Struct Biol, 158 (3), 386-400
DOI 10.1016/j.jsb.2006.12.006, PubMed 17287132
Raiborg C (2006)
Hrs makes receptors silent: a key to endosomal protein sorting
Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
DOI 10.1615/critrevoncog.v12.i3-4.70, PubMed 17425508
Raiborg C, Slagsvold T, Stenmark H (2006)
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
DOI 10.1016/j.tibs.2006.07.009, PubMed 16901703
Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
DOI 10.1242/jcs.02978, PubMed 16720641
Ralph E, Boye E, Kearsey SE (2006)
DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1
EMBO Rep, 7 (11), 1134-9
DOI 10.1038/sj.embor.7400827, PubMed 17039252
Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
DOI 10.1091/mbc.e06-03-0239, PubMed 16837550
Rusten TE, Stenmark H (2006)
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
DOI 10.1038/nmeth867, PubMed 16554828
Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
DOI 10.1242/jcs.03153, PubMed 16954148
Shahzidi S, Stokke T, Soltani H, Nesland JM, Peng Q (2006)
Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM
J Environ Pathol Toxicol Oncol, 25 (1-2), 159-71
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.90, PubMed 16566715
Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
DOI 10.1038/sj.emboj.7601267, PubMed 16888620
Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
DOI 10.1016/j.tcb.2006.04.004, PubMed 16716591
Slominska-Wojewodzka M, Gregers TF, Wälchli S, Sandvig K (2006)
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
Mol Biol Cell, 17 (4), 1664-75
DOI 10.1091/mbc.e05-10-0961, PubMed 16452630
Sørensen V, Nilsen T, Wiedłocha A (2006)
Functional diversity of FGF-2 isoforms by intracellular sorting
Bioessays, 28 (5), 504-14
DOI 10.1002/bies.20405, PubMed 16615083
Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
DOI 10.1242/jcs.03209, PubMed 17003104
Utskarpen A, Slagsvold HH, Iversen TG, Wälchli S, Sandvig K (2006)
Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
Traffic, 7 (6), 663-72
DOI 10.1111/j.1600-0854.2006.00418.x, PubMed 16683916
Wesche J, Małecki J, Wiedłocha A, Skjerpen CS, Claus P, Olsnes S (2006)
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
DOI 10.1074/jbc.M600477200, PubMed 16495214
Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2006)
Structural requirements of FGF-1 for receptor binding and translocation into cells
Biochemistry, 45 (51), 15338-48
DOI 10.1021/bi0618114, PubMed 17176056

Publications 2005

Bach T, Skarstad K (2005)
An oriC-like distribution of GATC sites mediates full sequestration of non-origin sequences in Escherichia coli
J Mol Biol, 350 (1), 7-11
DOI 10.1016/j.jmb.2005.04.055, PubMed 15922360
Bates D, Epstein J, Boye E, Fahrner K, Berg H, Kleckner N (2005)
The Escherichia coli baby cell column: a novel cell synchronization method provides new insight into the bacterial cell cycle
Mol Microbiol, 57 (2), 380-91
DOI 10.1111/j.1365-2958.2005.04693.x, PubMed 15978072
Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
DOI 10.1083/jcb.200507002, PubMed 16286508
Cabezas A, Bache KG, Brech A, Stenmark H (2005)
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
DOI 10.1242/jcs.02382, PubMed 15914539
Canales J, Cabezas A, Pinto RM, Cameselle JC (2005)
Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
Anal Biochem, 341 (2), 214-9
DOI 10.1016/j.ab.2005.01.060, PubMed 15907866
Drevon T, Slagsvold T (2005)
When and from whom do female pied flycatchers (Ficedula hypoleuca) solicit copulations
Behaviour, 142, 1059-1076
DOI 10.1163/156853905774405335
Grimmer S, Ying M, Wälchli S, van Deurs B, Sandvig K (2005)
Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
Traffic, 6 (2), 144-56
DOI 10.1111/j.1600-0854.2005.00258.x, PubMed 15634214
Guerra L, Teter K, Lilley BN, Stenerlöw B, Holmes RK, Ploegh HL, Sandvig K, Thelestam M, Frisan T (2005)
Cellular internalization of cytolethal distending toxin: a new end to a known pathway
Cell Microbiol, 7 (7), 921-34
DOI 10.1111/j.1462-5822.2005.00520.x, PubMed 15953025
Haugsten EM, Sørensen V, Brech A, Olsnes S, Wesche J (2005)
Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
J Cell Sci, 118 (Pt 17), 3869-81
DOI 10.1242/jcs.02509, PubMed 16091423
Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C (2005)
The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
J Neurosci, 25 (11), 2793-802
DOI 10.1523/JNEUROSCI.4090-04.2005, PubMed 15772339
Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
DOI 10.1016/j.cell.2005.02.017, PubMed 15882625
Hommelgaard AM, Roepstorff K, Vilhardt F, Torgersen ML, Sandvig K, van Deurs B (2005)
Caveolae: stable membrane domains with a potential for internalization
Traffic, 6 (9), 720-4
DOI 10.1111/j.1600-0854.2005.00314.x, PubMed 16101676
Høiseth G, Olsnes S (2005)
[Ricin--a therapeutic agent and a biological weapon]
Tidsskr Nor Laegeforen, 125 (18), 2477-9
PubMed 16186864
Ibrahim SO, Miron T, Krohn M, Amaratunga AN, Warnakulasauriya S, Vasstrand EN (2005)
Tumour-associated Proteins in Oral Squamous Cell Carcinomas by Proteomics
Cancer Genomics Proteomics, 2 (6), 353-363
PubMed 31394652
Johannessen LE, Slagsvold T, Hansen BT, Lifjeld JT (2005)
Manipulation of male quality in wild tits: effects on paternity loss
Behav. Ecol., 16 (4), 747-754
DOI 10.1093/beheco/ari048
Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
DOI 10.1111/j.1742-4658.2004.04387.x, PubMed 15634330
Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
Shiga toxin regulates its entry in a Syk-dependent manner
Mol Biol Cell, 17 (3), 1096-109
DOI 10.1091/mbc.e05-08-0766, PubMed 16371508
Lindstad RI, Sylte I, Mikalsen SO, Seglen PO, Berg E, Winberg JO (2005)
Pancreatic trypsin activates human promatrix metalloproteinase-2
J Mol Biol, 350 (4), 682-98
DOI 10.1016/j.jmb.2005.05.018, PubMed 15950241
Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH (2005)
Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
Int J Cancer, 116 (3), 359-67
DOI 10.1002/ijc.21015, PubMed 15800944
Morigen, Molina F, Skarstad K (2005)
Deletion of the datA site does not affect once-per-cell-cycle timing but induces rifampin-resistant replication
J Bacteriol, 187 (12), 3913-20
DOI 10.1128/JB.187.12.3913-3920.2005, PubMed 15939703
Odsbu I, Klungsøyr HK, Fossum S, Skarstad K (2005)
Specific N-terminal interactions of the Escherichia coli SeqA protein are required to form multimers that restrain negative supercoils and form foci
Genes Cells, 10 (11), 1039-49
DOI 10.1111/j.1365-2443.2005.00898.x, PubMed 16236133
Samari HR, Møller MT, Holden L, Asmyhr T, Seglen PO (2005)
Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins
Biochem J, 386 (Pt 2), 237-44
DOI 10.1042/BJ20040609, PubMed 15461583
Sandvig K, van Deurs B (2005)
Delivery into cells: lessons learned from plant and bacterial toxins
Gene Ther, 12 (11), 865-72
DOI 10.1038/sj.gt.3302525, PubMed 15815697
Sioud M, Wälchli S (2005)
Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
Methods Mol Biol, 309, 83-91
DOI 10.1385/1-59259-935-4:083, PubMed 15990399
Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
DOI 10.1074/jbc.M501510200, PubMed 15755741
Sneve ML, Øverbye A, Fengsrud M, Seglen PO (2005)
Comigration of two autophagosome-associated dehydrogenases on two-dimensional polyacrylamide gels
Autophagy, 1 (3), 157-62
DOI 10.4161/auto.1.3.2037, PubMed 16874067
Spilsberg B, Hanada K, Sandvig K (2005)
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
Biochem Biophys Res Commun, 329 (2), 465-73
DOI 10.1016/j.bbrc.2005.02.005, PubMed 15737610
Spilsberg B, Sandvig K, Wälchli S (2005)
Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
Toxicon, 46 (8), 900-6
DOI 10.1016/j.toxicon.2005.08.015, PubMed 16260019
Stige LC, Slagsvold T, Vollestad LA (2005)
Individual fluctuating asymmetry in pied flycatchers (Ficedula hypoleuca) persists across moults, but is not heritable and not related to fitness
Evol. Ecol. Res., 7 (3), 381-406
Torgersen ML, Lauvrak SU, Sandvig K (2005)
The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
FEBS J, 272 (16), 4103-13
DOI 10.1111/j.1742-4658.2005.04835.x, PubMed 16098193
Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
DOI 10.1016/j.ejcb.2004.12.029, PubMed 16032929
Wesche J, Małecki J, Wiedłocha A, Ehsani M, Marcinkowska E, Nilsen T, Olsnes S (2005)
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
DOI 10.1021/bi047403m, PubMed 15835896
Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2005)
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
J Mol Biol, 352 (4), 860-75
DOI 10.1016/j.jmb.2005.07.066, PubMed 16126225

Publications 2004

Bach T, Skarstad K (2004)
Re-replication from non-sequesterable origins generates three-nucleoid cells which divide asymmetrically
Mol Microbiol, 51 (6), 1589-600
DOI 10.1111/j.1365-2958.2003.03943.x, PubMed 15009887
Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
DOI 10.1091/mbc.e04-03-0250, PubMed 15240819
Bache KG, Slagsvold T, Stenmark H (2004)
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
DOI 10.1038/sj.emboj.7600292, PubMed 15229652
Birkeland HC, Stenmark H (2004)
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
DOI 10.1007/978-3-642-18805-3_4, PubMed 14594215
Engelhardt M, Pfadenhauer K, Zentner J, Grimmer S, Wachenfeld-Wahl C, Heidenreich P, Loeprecht H, Wölfle KD (2004)
[Impaired cerebral autoregulation in asymptomatic patients with carotid artery stenosis: comparison of acetazolamide-SPECT and transcranial CO(2)-dopplersonography]
Zentralbl Chir, 129 (3), 178-82
DOI 10.1055/s-2004-822798, PubMed 15237321
Gruenberg J, Stenmark H (2004)
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
DOI 10.1038/nrm1360, PubMed 15071556
Hansen BT, Slagsvold T (2004)
Early learning affects social dominance: interspecifically cross-fostered tits become subdominant
Behav. Ecol., 15 (2), 262-268
DOI 10.1093/beheco/arh010
Jacobs CM, Boldingh KA, Slagsvold HH, Thoresen GH, Paulsen RE (2004)
ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3
J Biol Chem, 279 (48), 50097-101
DOI 10.1074/jbc.M409145200, PubMed 15448159
Johnson HM, Subramaniam PS, Olsnes S, Jans DA (2004)
Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
Bioessays, 26 (9), 993-1004
DOI 10.1002/bies.20086, PubMed 15351969
Klungsøyr HK, Skarstad K (2004)
Positive supercoiling is generated in the presence of Escherichia coli SeqA protein
Mol Microbiol, 54 (1), 123-31
DOI 10.1111/j.1365-2958.2004.04239.x, PubMed 15458410
Kourmanova AG, Soudarkina OJ, Olsnes S, Kozlov JV (2004)
Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
Eur J Biochem, 271 (12), 2350-60
DOI 10.1111/j.1432-1033.2004.04153.x, PubMed 15182350
Kowanetz K, Crosetto N, Haglund K, Schmidt MHH, Heldin CH, Dikic I (2004)
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
J Biol Chem, 279 (31), 32786-95
DOI 10.1074/jbc.M403759200, PubMed 15159412
Lauvrak SU, Torgersen ML, Sandvig K (2004)
Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
J Cell Sci, 117 (Pt 11), 2321-31
DOI 10.1242/jcs.01081, PubMed 15126632
Loog M, Oskolkov N, O'Farrell F, Ek P, Järv J (2004)
Comparison of cAMP-dependent protein kinase substrate specificity in reaction with proteins and synthetic peptides
Biochim Biophys Acta, 1747 (2), 261-6
DOI 10.1016/j.bbapap.2004.11.016, PubMed 15698961
Masson V, de la Ballina LR, Munaut C, Wielockx B, Jost M, Maillard C, Blacher S, Bajou K, Itoh T, Itohara S, Werb Z, Libert C, Foidart JM, Noël A (2004)
Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes
FASEB J, 19 (2), 234-6
DOI 10.1096/fj.04-2140fje, PubMed 15550552
Molina F, Skarstad K (2004)
Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism
Mol Microbiol, 52 (6), 1597-612
DOI 10.1111/j.1365-2958.2004.04097.x, PubMed 15186411
Møller MT, Samari HR, Seglen PO (2004)
Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation
Toxicol Sci, 82 (2), 628-37
DOI 10.1093/toxsci/kfh273, PubMed 15342961
Nilssen EA, Synnes M, Tvegård T, Vebø H, Boye E, Grallert B (2004)
Germinating fission yeast spores delay in G1 in response to UV irradiation
BMC Cell Biol, 5 (1), 40
DOI 10.1186/1471-2121-5-40, PubMed 15498101
Olsnes S (2004)
The history of ricin, abrin and related toxins
Toxicon, 44 (4), 361-70
DOI 10.1016/j.toxicon.2004.05.003, PubMed 15302520
Ramírez M, Vinagre A, Ambrona J, Molina F, Maqueda M, Rebollo JE (2004)
Genetic instability of heterozygous, hybrid, natural wine yeasts
Appl Environ Microbiol, 70 (8), 4686-91
DOI 10.1128/AEM.70.8.4686-4691.2004, PubMed 15294803
Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
DOI 10.1016/j.devcel.2004.07.005, PubMed 15296715
Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
Pathways followed by protein toxins into cells
Int J Med Microbiol, 293 (7-8), 483-90
DOI 10.1078/1438-4221-00294, PubMed 15149022
Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
DOI 10.1083/jcb.200312018, PubMed 15007060
Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
DOI 10.1242/jcs.01287, PubMed 15292400
Slagsvold T, Stenmark H (2004)
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
DOI 10.1016/j.devcel.2004.09.007, PubMed 15469831
Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
DOI 10.1091/mbc.e04-01-0041, PubMed 15194809
Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
J Cell Sci, 117 (Pt 9), 1807-19
DOI 10.1242/jcs.01047, PubMed 15075241
Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
Mol Cell Biol, 24 (10), 4593-604
DOI 10.1128/MCB.24.10.4593-4604.2004, PubMed 15121875
Wiedłocha A, Nilsen T, Wesche J, Sørensen V, Małecki J, Marcinkowska E, Olsnes S (2004)
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
DOI 10.1091/mbc.e04-05-0389, PubMed 15574884
Wiedłocha A, Sørensen V (2004)
Signaling, internalization, and intracellular activity of fibroblast growth factor
Curr Top Microbiol Immunol, 286, 45-79
DOI 10.1007/978-3-540-69494-6_3, PubMed 15645710
Zakrzewska M, Krowarsch D, Wiedlocha A, Otlewski J (2004)
Design of fully active FGF-1 variants with increased stability
Protein Eng Des Sel, 17 (8), 603-11
DOI 10.1093/protein/gzh076, PubMed 15469994

Publications 2003

Bach T, Krekling MA, Skarstad K (2003)
Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division
EMBO J, 22 (2), 315-23
DOI 10.1093/emboj/cdg020, PubMed 12514137
Bache KG, Brech A, Mehlum A, Stenmark H (2003)
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
DOI 10.1083/jcb.200302131, PubMed 12900395
Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
DOI 10.1074/jbc.M210843200, PubMed 12551915
Boye E, Nordström K (2003)
Coupling the cell cycle to cell growth
EMBO Rep, 4 (8), 757-60
DOI 10.1038/sj.embor.embor895, PubMed 12897798
Bråthe A, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2003)
Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
Bioorg Med Chem Lett, 13 (5), 877-80
DOI 10.1016/s0960-894x(03)00011-8, PubMed 12617912
Camara JE, Skarstad K, Crooke E (2003)
Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein
J Bacteriol, 185 (10), 3244-8
DOI 10.1128/JB.185.10.3244-3248.2003, PubMed 12730188
Duś D, Krawczenko A, Załecki P, Paprocka M, Wiedłocha A, Goupille C, Kieda C (2003)
IL-7 receptor is present on human microvascular endothelial cells
Immunol Lett, 86 (2), 163-8
DOI 10.1016/s0165-2478(03)00018-x, PubMed 12644318
Fossum S, Søreide S, Skarstad K (2003)
Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2
Mol Microbiol, 47 (3), 619-32
DOI 10.1046/j.1365-2958.2003.t01-1-03329.x, PubMed 12535065
Furre T, Furre EI, Koritzinsky M, Amellem Ø, Pettersen EO (2003)
Lack of inverse dose-rate effect and binding of the retinoblastoma gene product in the nucleus of human cancer T-47D cells arrested in G2 by ionizing radiation
Int J Radiat Biol, 79 (6), 413-22
DOI 10.1080/0955300031000140784, PubMed 12963543
Gillooly DJ, Raiborg C, Stenmark H (2003)
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
DOI 10.1007/s00418-003-0591-7, PubMed 14618335
González-Gaitán M, Stenmark H (2003)
Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
DOI 10.1016/s0092-8674(03)00932-2, PubMed 14651844
Gregers TF, Nordeng TW, Birkeland HC, Sandlie I, Bakke O (2003)
The cytoplasmic tail of invariant chain modulates antigen processing and presentation
Eur J Immunol, 33 (2), 277-86
DOI 10.1002/immu.200310001, PubMed 12548558
Holme HK, Lindmo K, Kristiansen A, Smidsrod O (2003)
Thermal depolymerization of alginate in the solid state
Carbohydr. Polym., 54 (4), 431-438
DOI 10.1016/S0144-8617(03)00134-6
Iversen TG, Skretting G, van Deurs B, Sandvig K (2003)
Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
Proc Natl Acad Sci U S A, 100 (9), 5175-80
DOI 10.1073/pnas.0534231100, PubMed 12682302
Kang S, Han JS, Park JH, Skarstad K, Hwang DS (2003)
SeqA protein stimulates the relaxing and decatenating activities of topoisomerase IV
J Biol Chem, 278 (49), 48779-85
DOI 10.1074/jbc.M308843200, PubMed 14512422
Kolpakova E, Rusten TE, Olsnes S (2003)
Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
Gene, 310, 185-91
DOI 10.1016/s0378-1119(03)00550-x, PubMed 12801646
Kowanetz K, Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K, Taylor JD, Soubeyran P, Engstrom U, Ladbury JE, Dikic I (2003)
Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
J Biol Chem, 278 (41), 39735-46
DOI 10.1074/jbc.M304541200, PubMed 12874286
Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
J Biol Chem, 278 (37), 35850-5
DOI 10.1074/jbc.M303425200, PubMed 12847103
Małecki J, Wesche J, Skjerpen CS, Wiedłocha A, Olsnes S (2003)
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
Mol Biol Cell, 15 (2), 801-14
DOI 10.1091/mbc.e03-08-0589, PubMed 14657241
Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
DOI 10.1016/s1534-5807(03)00321-6, PubMed 14602072
Marcinkowska E, Wiedlocha A (2003)
Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
Anticancer Res, 23 (5A), 4071-7
PubMed 14666721
Miller C, Ingmer H, Thomsen LE, Skarstad K, Cohen SN (2003)
DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response
J Bacteriol, 185 (20), 6025-31
DOI 10.1128/JB.185.20.6025-6031.2003, PubMed 14526013
Morigen, Løbner-Olesen A, Skarstad K (2003)
Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks, delayed replication initiation and delayed cell division
Mol Microbiol, 50 (1), 349-62
DOI 10.1046/j.1365-2958.2003.03695.x, PubMed 14507385
Mousavi SA, Brech A, Berg T, Kjeken R (2003)
Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
Biochem J, 372 (Pt 3), 861-9
DOI 10.1042/BJ20021136, PubMed 12646047
Møller MT, Samari HR, Fengsrud M, Strømhaug PE, øStvold AC, Seglen PO (2003)
Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes
Biochem J, 373 (Pt 2), 505-13
DOI 10.1042/BJ20030502, PubMed 12697024
Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
DOI 10.1074/jbc.M309653200, PubMed 14604990
Nilssen EA, Synnes M, Kleckner N, Grallert B, Boye E (2003)
Intra-G1 arrest in response to UV irradiation in fission yeast
Proc Natl Acad Sci U S A, 100 (19), 10758-63
DOI 10.1073/pnas.1833769100, PubMed 12960401
Olsnes S, Klingenberg O, Wiedłocha A (2003)
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
DOI 10.1152/physrev.00021.2002, PubMed 12506129
Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
J Cell Biol, 162 (6), 971-9
DOI 10.1083/jcb.200303018, PubMed 12975344
Raiborg C, Rusten TE, Stenmark H (2003)
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
DOI 10.1016/s0955-0674(03)00080-2, PubMed 12892785
Rojo MA, Citores L, Jiménez P, Ferreras JM, Arias FJ, Méndez E, Girbés T (2003)
Isolation and characterization of a new d-galactose-binding lectin from Sambucus racemosa L
Protein Pept Lett, 10 (3), 287-93
DOI 10.2174/0929866033478979, PubMed 12871149
Sandvig K, van Deurs B (2003)
Cholera toxin internalization and intoxication - Reply
J. Cell Sci., 116 (3), 432-433
DOI 10.1242/jcs.00200
Schedlich LJ, Nilsen T, John AP, Jans DA, Baxter RC (2003)
Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation
Endocrinology, 144 (5), 1984-93
DOI 10.1210/en.2002-220798, PubMed 12697706
Skarstad K, Boye E, Fanning E (2003)
Circles in the sand
EMBO Rep, 4 (7), 661-5
DOI 10.1038/sj.embor.embor888, PubMed 12835752
Skarstad K, Løbner-Olesen A (2003)
Stable co-existence of separate replicons in Escherichia coli is dependent on once-per-cell-cycle initiation
EMBO J, 22 (1), 140-50
DOI 10.1093/emboj/cdg003, PubMed 12505992
Slominska M, Wahl A, Wegrzyn G, Skarstad K (2003)
Degradation of mutant initiator protein DnaA204 by proteases ClpP, ClpQ and Lon is prevented when DNA is SeqA-free
Biochem J, 370 (Pt 3), 867-71
DOI 10.1042/BJ20021161, PubMed 12479794
Spilsberg B, Van Meer G, Sandvig K (2003)
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-52
DOI 10.1034/j.1600-0854.2003.00111.x, PubMed 12839497
Storen T, Simonsen A, Royset AK, Lokberg OJ, Svaasand LO, Lindmo T (2003)
Time resolved spectroscopic optical coherence tomography for diffusion measurements
P SOC PHOTO-OPT INS, 4956, 197-204
DOI 10.1117/12.477645
van Deurs B, Roepstorff K, Hommelgaard AM, Sandvig K (2003)
Caveolae: anchored, multifunctional platforms in the lipid ocean
Trends Cell Biol, 13 (2), 92-100
DOI 10.1016/s0962-8924(02)00039-9, PubMed 12559760
Ying M, Grimmer S, Iversen TG, Van Deurs B, Sandvig K (2003)
Cholesterol loading induces a block in the exit of VSVG from the TGN
Traffic, 4 (11), 772-84
DOI 10.1034/j.1600-0854.2003.00134.x, PubMed 14617359

Publications 2002

Andresen G, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2002)
Cytotoxic and antibacterial activity of 2-oxopurine derivatives
Bioorg Med Chem Lett, 12 (4), 567-9
DOI 10.1016/s0960-894x(01)00803-4, PubMed 11844673
Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
DOI 10.1046/j.1432-1033.2002.03046.x, PubMed 12180964
Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
J Biol Chem, 278 (3), 1991-7
DOI 10.1074/jbc.M209982200, PubMed 12419802
Braathen R, Sorensen V, Brandtzaeg P, Sandlie I, Johansen FE (2002)
The carboxyl-terminal domains of IgA and IgM direct isotype-specific polymerization and interaction with the polymeric immunoglobulin receptor
J Biol Chem, 277 (45), 42755-62
DOI 10.1074/jbc.M205502200, PubMed 12213814
Grimmer S, van Deurs B, Sandvig K (2002)
Membrane ruffling and macropinocytosis in A431 cells require cholesterol
J Cell Sci, 115 (Pt 14), 2953-62
DOI 10.1242/jcs.115.14.2953, PubMed 12082155
Gundersen LL, Nissen-Meyer J, Spilsberg B (2002)
Synthesis and antimycobacterial activity of 6-arylpurines: the requirements for the N-9 substituent in active antimycobacterial purines
J Med Chem, 45 (6), 1383-6
DOI 10.1021/jm0110284, PubMed 11882008
Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
J Cell Sci, 115 (Pt 5), 899-911
DOI 10.1242/jcs.115.5.899, PubMed 11870209
Lagaudrière-Gesbert C, Newmyer SL, Gregers TF, Bakke O, Ploegh HL (2002)
Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments
Proc Natl Acad Sci U S A, 99 (3), 1515-20
DOI 10.1073/pnas.042688099, PubMed 11818572
Larsen AK, Møller MT, Blankson H, Samari HR, Holden L, Seglen PO (2002)
Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes
J Biol Chem, 277 (38), 34826-35
DOI 10.1074/jbc.M205028200, PubMed 12095991
Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
J Cell Sci, 115 (Pt 17), 3449-56
DOI 10.1242/jcs.115.17.3449, PubMed 12154075
Luk'ianov EV, Viedlokha A, Kuianskaia DV, Olsnes S, Kozlov IuV (2002)
[A short form of the heparin-binding EGF-like growth factor with a changed EGF domain]
Mol Biol (Mosk), 36 (1), 76-83
PubMed 11862716
Luk'yanov EV, Viedlokha A, Kuyavskaya DV, Olsnes S, Kozlov YV (2002)
A short form of the heparin-binding EGF-like growth factor with a changed EGF domain
Mol. Biol., 36 (1), 58-64
DOI 10.1023/A:1014246423243
Małecki J, Wiedłocha A, Wesche J, Olsnes S (2002)
Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1
EMBO J, 21 (17), 4480-90
DOI 10.1093/emboj/cdf472, PubMed 12198150
Marcinkowska E, Wiedłocha A (2002)
Steroid signal transduction activated at the cell membrane: from plants to animals
Acta Biochim Pol, 49 (3), 735-45
PubMed 12422243
Murray JT, Panaretou C, Stenmark H, Miaczynska M, Backer JM (2002)
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
Traffic, 3 (6), 416-27
DOI 10.1034/j.1600-0854.2002.30605.x, PubMed 12010460
Nordeng TW, Gregers TF, Kongsvik TL, Méresse S, Gorvel JP, Jourdan F, Motta A, Bakke O (2002)
The cytoplasmic tail of invariant chain regulates endosome fusion and morphology
Mol Biol Cell, 13 (6), 1846-56
DOI 10.1091/mbc.01-10-0478, PubMed 12058053
Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T (2002)
Early endosomal regulation of Smad-dependent signaling in endothelial cells
J Biol Chem, 277 (20), 18046-52
DOI 10.1074/jbc.M107983200, PubMed 11877415
Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
DOI 10.1038/ncb791, PubMed 11988743
Raiborg C, Stenmark H (2002)
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
DOI 10.1247/csf.27.403, PubMed 12576633
Roepstorff K, Thomsen P, Sandvig K, van Deurs B (2002)
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
J Biol Chem, 277 (21), 18954-60
DOI 10.1074/jbc.M201422200, PubMed 11886870
Sandvig K, van Deurs B (2002)
Membrane traffic exploited by protein toxins
Annu Rev Cell Dev Biol, 18, 1-24
DOI 10.1146/annurev.cellbio.18.011502.142107, PubMed 12142266
Sandvig K, van Deurs B (2002)
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
FEBS Lett, 529 (1), 49-53
DOI 10.1016/s0014-5793(02)03182-4, PubMed 12354612
Shimokawa N, Okada J, Haglund K, Dikic I, Koibuchi N, Miura M (2002)
Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain
J Neurosci, 22 (21), 9160-5
DOI 10.1523/JNEUROSCI.22-21-09160.2002, PubMed 12417639
Skjerpen CS, Nilsen T, Wesche J, Olsnes S (2002)
Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity
EMBO J, 21 (15), 4058-69
DOI 10.1093/emboj/cdf402, PubMed 12145206
Skjerpen CS, Wesche J, Olsnes S (2002)
Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
J Biol Chem, 277 (26), 23864-71
DOI 10.1074/jbc.M112193200, PubMed 11964394
Stenmark H, Aasland R, Driscoll PC (2002)
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
DOI 10.1016/s0014-5793(01)03308-7, PubMed 11911884
Synnes M, Nilssen EA, Boye E, Grallert B (2002)
A novel chk1-dependent G1/M checkpoint in fission yeast
J Cell Sci, 115 (Pt 18), 3609-18
DOI 10.1242/jcs.00004, PubMed 12186947
Tse SM, Furuya W, Gold E, Schreiber AD, Sandvig K, Inman RD, Grinstein S (2002)
Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
J Biol Chem, 278 (5), 3331-8
DOI 10.1074/jbc.M207966200, PubMed 12424246
Wabakken T, Hauge H, Finne EF, Wiedlocha A, Aasheim H (2002)
Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase
Scand J Immunol, 56 (2), 195-203
DOI 10.1046/j.1365-3083.2002.01126.x, PubMed 12121439
Wesche J (2002)
Retrograde transport of ricin
Int J Med Microbiol, 291 (6-7), 517-21
DOI 10.1078/1438-4221-00161, PubMed 11890552

Publications 2001

Berven G, Saetre F, Halvorsen K, Seglen PO (2001)
Effects of the diarrhetic shellfish toxin, okadaic acid, on cytoskeletal elements, viability and functionality of rat liver and intestinal cells
Toxicon, 39 (2-3), 349-62
DOI 10.1016/s0041-0101(00)00137-9, PubMed 10978754
Boye E, Blinkova A, Walker JR (2001)
Defective initiation in an Escherichia coli dnaA(Cs,Sx) mutant
Biochimie, 83 (1), 25-32
DOI 10.1016/s0300-9084(00)01230-x, PubMed 11254971
Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wiedłocha A, Olsnes S (2001)
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
DOI 10.1242/jcs.114.9.1677, PubMed 11398757
Falnes PØ, Wesche J, Olsnes S (2001)
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
Biochemistry, 40 (14), 4349-58
DOI 10.1021/bi002443l, PubMed 11284691
Garred Ø, Rodal SK, van Deurs B, Sandvig K (2001)
Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
Traffic, 2 (1), 26-36
DOI 10.1034/j.1600-0854.2001.020105.x, PubMed 11208166
Gillooly DJ, Simonsen A, Stenmark H (2001)
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
Biochem J, 355 (Pt 2), 249-58
DOI 10.1042/0264-6021:3550249, PubMed 11284710
Gillooly DJ, Simonsen A, Stenmark H (2001)
Phosphoinositides and phagocytosis
J Cell Biol, 155 (1), 15-7
DOI 10.1083/jcb.200109001, PubMed 11581282
Gillooly DJ, Stenmark H (2001)
Cell biology. A lipid oils the endocytosis machine
Science, 291 (5506), 993-4
DOI 10.1126/science.291.5506.993, PubMed 11232585
Iversen TG, Skretting G, Llorente A, Nicoziani P, van Deurs B, Sandvig K (2001)
Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
Mol Biol Cell, 12 (7), 2099-107
DOI 10.1091/mbc.12.7.2099, PubMed 11452006
Kim DH, Eu YJ, Yoo CM, Kim YW, Pih KT, Jin JB, Kim SJ, Stenmark H, Hwang I (2001)
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
Plant Cell, 13 (2), 287-301
DOI 10.1105/tpc.13.2.287, PubMed 11226186
Kim J, Kamada Y, Stromhaug PE, Guan J, Hefner-Gravink A, Baba M, Scott SV, Ohsumi Y, Dunn WA, Klionsky DJ (2001)
Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole
J Cell Biol, 153 (2), 381-96
DOI 10.1083/jcb.153.2.381, PubMed 11309418
Kjeken R, Mousavi SA, Brech A, Gjøen T, Berg T (2001)
Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells
Cell Tissue Res, 304 (2), 221-30
DOI 10.1007/s004410100348, PubMed 11396716
Kjeken R, Mousavi SA, Brech A, Griffiths G, Berg T (2001)
Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
Biochem J, 357 (Pt 2), 497-503
DOI 10.1042/0264-6021:3570497, PubMed 11439100
Koritzinsky M, Wouters BG, Amellem O, Pettersen EO (2001)
Cell cycle progression and radiation survival following prolonged hypoxia and re-oxygenation
Int J Radiat Biol, 77 (3), 319-28
DOI 10.1080/09553000010019278, PubMed 11258846
Llorente A, Prydz K, Sprangers M, Skretting G, Kolset SO, Sandvig K (2001)
Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
J Cell Sci, 114 (Pt 2), 335-43
DOI 10.1242/jcs.114.2.335, PubMed 11148135
Loukianov EV, Wiedlocha A, Olsnes S, Kozlov YV (2001)
Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
Mol. Biol., 35 (1), 122-129
DOI 10.1023/A:1004819321876
Luk'ianov EV, Viedlokha A, Olsnes S, Kozlov IuV (2001)
[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
Mol Biol (Mosk), 35 (1), 136-45
PubMed 11234372
Lunde E, Rasmussen IB, Eidem JK, Gregers TF, Western KH, Bogen B, Sandlie I (2001)
'Troy-bodies': antibodies as vector proteins for T cell epitopes
Biomol Eng, 18 (3), 109-16
DOI 10.1016/s1389-0344(01)00091-0, PubMed 11566602
Marcinkowska E, Chrobak A, Wiedłocha A (2001)
Evading apoptosis by calcitriol-differentiated human leukemic HL-60 cells is not mediated by changes in CD95 receptor system but by increased sensitivity of these cells to insulin
Exp Cell Res, 270 (1), 119-27
DOI 10.1006/excr.2001.5335, PubMed 11597134
Morigen, Boye E, Skarstad K, Løbner-Olesen A (2001)
Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the datA region
Biochim Biophys Acta, 1521 (1-3), 73-80
DOI 10.1016/s0167-4781(01)00292-5, PubMed 11690638
Mousavi SA, Kjeken R, Berg TO, Seglen PO, Berg T, Brech A (2001)
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
Biochim Biophys Acta, 1510 (1-2), 243-57
DOI 10.1016/s0005-2736(00)00354-0, PubMed 11342162
Olsnes S, Kozlov JV (2001)
Ricin
Toxicon, 39 (11), 1723-8
DOI 10.1016/s0041-0101(01)00158-1, PubMed 11595634
Olsnes S, Wesche J (2001)
Microbiology. Fighting anthrax with a mutant toxin
Science, 292 (5517), 647-8
DOI 10.1126/science.1060857, PubMed 11330322
Pattni K, Jepson M, Stenmark H, Banting G (2001)
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
Curr Biol, 11 (20), 1636-42
DOI 10.1016/s0960-9822(01)00486-9, PubMed 11676927
Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H (2001)
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
DOI 10.1093/emboj/20.17.5008, PubMed 11532964
Raiborg C, Bache KG, Mehlum A, Stenmark H (2001)
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
DOI 10.1042/bst0290472, PubMed 11498011
Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H (2001)
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
DOI 10.1242/jcs.114.12.2255, PubMed 11493665
Sandvig K (2001)
Shiga toxins
Toxicon, 39 (11), 1629-35
DOI 10.1016/s0041-0101(01)00150-7, PubMed 11595626
Sandvig K, Grimmer S, Lauvrak SU, Torgersen ML, Skretting G, van Deurs B, Iversen TG (2001)
Pathways followed by ricin and Shiga toxin into cells
Histochem Cell Biol, 117 (2), 131-41
DOI 10.1007/s00418-001-0346-2, PubMed 11935289
Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2001)
In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
Int J Cancer, 92 (5), 761-6
DOI 10.1002/1097-0215(20010601)92:5<761::aid-ijc1238>3.0.co;2-4, PubMed 11340584
Simonsen A, Stenmark H (2001)
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
DOI 10.1038/35087112, PubMed 11483972
Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
DOI 10.1016/s0955-0674(00)00240-4, PubMed 11454456
Skarstad K, Torheim N, Wold S, Lurz R, Messer W, Fossum S, Bach T (2001)
The Escherichia coli SeqA protein binds specifically to two sites in fully and hemimethylated oriC and has the capacity to inhibit DNA replication and affect chromosome topology
Biochimie, 83 (1), 49-51
DOI 10.1016/s0300-9084(00)01207-4, PubMed 11254974
Slagsvold T, Kraus I, Frønsdal K, Saatcioglu F (2001)
DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
J Biol Chem, 276 (33), 31030-6
DOI 10.1074/jbc.M104310200, PubMed 11429409
Slomińska M, Wegrzyn A, Konopa G, Skarstad K, Wegrzyn G (2001)
SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
Mol Microbiol, 40 (6), 1371-9
DOI 10.1046/j.1365-2958.2001.02480.x, PubMed 11442835
Stenmark H (2001)
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
DOI 10.1006/scdb.2000.0230, PubMed 11292379
Stenmark H, Gillooly DJ (2001)
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
DOI 10.1006/scdb.2000.0236, PubMed 11292385
Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
DOI 10.1186/gb-2001-2-5-reviews3007, PubMed 11387043
Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol., 2 (5), 3007.1
Strømhaug PE, Bevan A, Dunn WA (2001)
GSA11 encodes a unique 208-kDa protein required for pexophagy and autophagy in Pichia pastoris
J Biol Chem, 276 (45), 42422-35
DOI 10.1074/jbc.M104087200, PubMed 11533052
Torgersen ML, Skretting G, van Deurs B, Sandvig K (2001)
Internalization of cholera toxin by different endocytic mechanisms
J Cell Sci, 114 (Pt 20), 3737-47
DOI 10.1242/jcs.114.20.3737, PubMed 11707525
Weigel C, Messer W, Preiss S, Welzeck M, Morigen, Boye E (2001)
The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome
Mol Microbiol, 40 (2), 498-507
DOI 10.1046/j.1365-2958.2001.02409.x, PubMed 11309131
Zheng W, Li Z, Skarstad K, Crooke E (2001)
Mutations in DnaA protein suppress the growth arrest of acidic phospholipid-deficient Escherichia coli cells
EMBO J, 20 (5), 1164-72
DOI 10.1093/emboj/20.5.1164, PubMed 11230139

Publications 2000

Bernander R, Skarstad K (2000)
Mapping of a chromosome replication origin in an archaeon
Trends Microbiol, 8 (12), 535-7
DOI 10.1016/s0966-842x(00)01878-3, PubMed 11115744
Blankson H, Grotterød EM, Seglen PO (2000)
Prevention of toxin-induced cytoskeletal disruption and apoptotic liver cell death by the grapefruit flavonoid, naringin
Cell Death Differ, 7 (8), 739-46
DOI 10.1038/sj.cdd.4400705, PubMed 10918448
Boye E, Løbner-Olesen A, Skarstad K (2000)
Limiting DNA replication to once and only once
EMBO Rep, 1 (6), 479-83
DOI 10.1093/embo-reports/kvd116, PubMed 11263490
Bremnes T, Paasche JD, Mehlum A, Sandberg C, Bremnes B, Attramadal H (2000)
Regulation and intracellular trafficking pathways of the endothelin receptors
J Biol Chem, 275 (23), 17596-604
DOI 10.1074/jbc.M000142200, PubMed 10747877
Dahl C, Haug LS, Spilsberg B, Johansen J, Ostvold AC, Diemer NH (2000)
Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction
Neurochem Int, 36 (4-5), 379-88
DOI 10.1016/s0197-0186(99)00129-1, PubMed 10733005
Day PJ, Owens SR, Wesche J, Olsnes S, Roberts LM, Lord JM (2000)
An interaction between ricin and calreticulin that may have implications for toxin trafficking
J Biol Chem, 276 (10), 7202-8
DOI 10.1074/jbc.M009499200, PubMed 11113144
Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, Desjardins M (2000)
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
J Cell Sci, 113 Pt 19, 3531-41
DOI 10.1242/jcs.113.19.3531, PubMed 10984443
Ebbesen P, Pettersen EO, Denekamp J, Littbrand B, Keski-Oja J, Schousboe A, Sonnewald U, Amellem O, Zachar V (2000)
Hypoxia, normoxia and hyperoxia--terminology for medical in vitro cell biology
Acta Oncol, 39 (2), 247-8
DOI 10.1080/028418600430888, PubMed 10859022
Eidem JK, Rasmussen IB, Lunde E, Gregers TF, Rees AR, Bogen B, Sandlie I (2000)
Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
J Immunol Methods, 245 (1-2), 119-31
DOI 10.1016/s0022-1759(00)00274-x, PubMed 11042289
Eliassen TM, Frøystad MK, Dannevig BH, Jankowska M, Brech A, Falk K, Romøren K, Gjøen T (2000)
Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step
J Virol, 74 (1), 218-27
DOI 10.1128/jvi.74.1.218-227.2000, PubMed 10590109
Falnes PO (2000)
Design of toxins that can be activated by cell-specific proteases and their potential use in targeted cell killing
Int J Med Microbiol, 290 (4-5), 471-6
DOI 10.1016/S1438-4221(00)80068-5, PubMed 11111928
Falnes PO, Ariansen S, Sandvig K, Olsnes S (2000)
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
J Biol Chem, 275 (6), 4363-8
DOI 10.1074/jbc.275.6.4363, PubMed 10660606
Falnes PO, Sandvig K (2000)
Penetration of protein toxins into cells
Curr Opin Cell Biol, 12 (4), 407-13
DOI 10.1016/s0955-0674(00)00109-5, PubMed 10873820
Fengsrud M, Erichsen ES, Berg TO, Raiborg C, Seglen PO (2000)
Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
Eur J Cell Biol, 79 (12), 871-82
DOI 10.1078/0171-9335-00125, PubMed 11152279
Fengsrud M, Raiborg C, Berg TO, Strømhaug PE, Ueno T, Erichsen ES, Seglen PO (2000)
Autophagosome-associated variant isoforms of cytosolic enzymes
Biochem J, 352 Pt 3 (Pt 3), 773-81
DOI 10.1042/0264-6021:3520773, PubMed 11104685
Gaullier JM, Ronning E, Gillooly DJ, Stenmark H (2000)
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
J Biol Chem, 275 (32), 24595-600
DOI 10.1074/jbc.M906554199, PubMed 10807926
Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H (2000)
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
DOI 10.1093/emboj/19.17.4577, PubMed 10970851
Grallert B, Kearsey SE, Lenhard M, Carlson CR, Nurse P, Boye E, Labib K (2000)
A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
J Cell Sci, 113 ( Pt 8), 1447-58
DOI 10.1242/jcs.113.8.1447, PubMed 10725227
Grimmer S, Iversen TG, van Deurs B, Sandvig K (2000)
Endosome to Golgi transport of ricin is regulated by cholesterol
Mol Biol Cell, 11 (12), 4205-16
DOI 10.1091/mbc.11.12.4205, PubMed 11102518
Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
DOI 10.1242/jcs.113.10.1827, PubMed 10769213
Klingenberg O, Wiedocha A, Citores L, Olsnes S (2000)
Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
J Biol Chem, 275 (16), 11972-80
DOI 10.1074/jbc.275.16.11972, PubMed 10766827
Kolpakova E, Frengen E, Stokke T, Olsnes S (2000)
Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
Biochem J, 352 Pt 3 (Pt 3), 629-35
DOI 10.1042/0264-6021:3520629, PubMed 11104667
Llorente A, van Deurs B, Garred O, Eker P, Sandvig K (2000)
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
J Cell Sci, 113 ( Pt 7), 1213-21
DOI 10.1242/jcs.113.7.1213, PubMed 10704372
Løvdal T, Andersen E, Brech A, Berg T (2000)
Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver
J Cell Sci, 113 ( Pt 18), 3255-66
DOI 10.1242/jcs.113.18.3255, PubMed 10954423
Nicoziani P, Vilhardt F, Llorente A, Hilout L, Courtoy PJ, Sandvig K, van Deurs B (2000)
Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
Mol Biol Cell, 11 (2), 481-95
DOI 10.1091/mbc.11.2.481, PubMed 10679008
Olsnes S, Falnes PO (2000)
Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
J Gen Physiol, 115 (4), 417-20
DOI 10.1085/jgp.115.4.417, PubMed 10736309
Pihl A, Bruland OS (2000)
Oral presentations in science and medicine. An art in decline?
Anticancer Res, 20 (5A), 2795-9
PubMed 11062686
Prosch-Danielsen L, Simonsen A (2000)
Palaeoecological investigations towards the reconstruction of the history of forest clearances and coastal heathlands in south-western Norway
Veg. Hist. Archaeobot., 9 (4), 189-204
DOI 10.1007/BF01294634
Sandvig K, Grimmer S, Iversen TG, Rodal K, Torgersen ML, Nicoziani P, van Deurs B (2000)
Ricin transport into cells: studies of endocytosis and intracellular transport
Int J Med Microbiol, 290 (4-5), 415-20
DOI 10.1016/S1438-4221(00)80055-7, PubMed 11111920
Sandvig K, Llorente A, Rodal SK, Eker P, Garred O, Stahlhut M, van Deurs B (2000)
Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
Eur J Cell Biol, 79 (7), 447-57
DOI 10.1078/0171-9335-00071, PubMed 10961444
Sandvig K, van Deurs B (2000)
Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
EMBO J, 19 (22), 5943-50
DOI 10.1093/emboj/19.22.5943, PubMed 11080141
Selbo PK, Sandvig K, Kirveliene V, Berg K (2000)
Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
Biochim Biophys Acta, 1475 (3), 307-13
DOI 10.1016/s0304-4165(00)00082-9, PubMed 10913830
Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>3.0.co;2-0, PubMed 10956397
Skarstad K, Lueder G, Lurz R, Speck C, Messer W (2000)
The Escherichia coli SeqA protein binds specifically and co-operatively to two sites in hemimethylated and fully methylated oriC
Mol Microbiol, 36 (6), 1319-26
DOI 10.1046/j.1365-2958.2000.01943.x, PubMed 10931282
Slagsvold T, Kraus I, Bentzen T, Palvimo J, Saatcioglu F (2000)
Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
Mol Endocrinol, 14 (10), 1603-17
DOI 10.1210/mend.14.10.0544, PubMed 11043576
Stahlhut M, Sandvig K, van Deurs B (2000)
Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
Exp Cell Res, 261 (1), 111-8
DOI 10.1006/excr.2000.4960, PubMed 11082281
Stenmark H (2000)
Cycling lipids
Curr Biol, 10 (2), R57-9
DOI 10.1016/s0960-9822(00)00279-7, PubMed 10662657
Torheim NK, Boye E, Løbner-Olesen A, Stokke T, Skarstad K (2000)
The Escherichia coli SeqA protein destabilizes mutant DnaA204 protein
Mol Microbiol, 37 (3), 629-38
DOI 10.1046/j.1365-2958.2000.02031.x, PubMed 10931356
Urbé S, Mills IG, Stenmark H, Kitamura N, Clague MJ (2000)
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
DOI 10.1128/MCB.20.20.7685-7692.2000, PubMed 11003664
von Freiesleben U, Krekling MA, Hansen FG, Løbner-Olesen A (2000)
The eclipse period of Escherichia coli
EMBO J, 19 (22), 6240-8
DOI 10.1093/emboj/19.22.6240, PubMed 11080169
Wesche J, Wiedłocha A, Falnes PO, Choe S, Olsnes S (2000)
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
DOI 10.1021/bi001831k, PubMed 11106487

Publications 1999

Baekkevold ES, Jahnsen FL, Johansen FE, Bakke O, Gaudernack G, Brandtzaeg P, Haraldsen G (1999)
Culture characterization of differentiated high endothelial venule cells from human tonsils
Lab Invest, 79 (3), 327-36
PubMed 10092069
Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
Cancer Res, 59 (6), 1180-3
PubMed 10096543
Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1999)
Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
DOI 10.1046/j.1432-1327.1999.00743.x, PubMed 10491193
Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1999)
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2) (Pt 2), 539-43
DOI 10.1042/0264-6021:3380539, PubMed 10024533
Carlson CR, Grallert B, Stokke T, Boye E (1999)
Regulation of the start of DNA replication in Schizosaccharomyces pombe
J Cell Sci, 112 ( Pt 6), 939-46
DOI 10.1242/jcs.112.6.939, PubMed 10036243
Citores L, Wesche J, Kolpakova E, Olsnes S (1999)
Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
Mol Biol Cell, 10 (11), 3835-48
DOI 10.1091/mbc.10.11.3835, PubMed 10564275
Corvera S, D'Arrigo A, Stenmark H (1999)
Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
DOI 10.1016/S0955-0674(99)80066-0, PubMed 10449332
Falnes PO, Welker R, Kräusslich HG, Olsnes S (1999)
Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway
Biochem J, 343 Pt 1 (Pt 1), 199-207
DOI 10.1042/0264-6021:3430199, PubMed 10493930
Furre T, Bergstrand ES, Pedersen E, Koritzinsky M, Olsen DR, Hole EO, Pettersen EO (1999)
Measurement of dose rate at the interface of cell culture medium and glass dishes by means of ESR dosimetry using thin films of alanine
Radiat Res, 152 (1), 76-82
DOI 10.2307/3580052, PubMed 10381844
Furre T, Koritzinsky M, Olsen DR, Pettersen EO (1999)
Inverse dose-rate effect due to pre-mitotic accumulation during continuous low dose-rate irradiation of cervix carcinoma cells
Int J Radiat Biol, 75 (6), 699-707
DOI 10.1080/095530099140032, PubMed 10404999
Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
DOI 10.1042/bst0270666, PubMed 10917663
Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1999)
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
DOI 10.1016/s0009-3084(99)00021-3, PubMed 10358931
Grallert A, Grallert B, Zilahi E, Szilagyi Z, Sipiczki M (1999)
Eleven novel sep genes of Schizosaccharomyces pombe required for efficient cell separation and sexual differentiation
Yeast, 15 (8), 669-86
DOI 10.1002/(SICI)1097-0061(19990615)15:8<669::AID-YEA411>3.0.CO;2-K, PubMed 10392445
Hjertner O, Torgersen ML, Seidel C, Hjorth-Hansen H, Waage A, Børset M, Sundan A (1999)
Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease
Blood, 94 (11), 3883-8
PubMed 10572104
Klingenberg O, Wiedlocha A, Olsnes S (1999)
Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
J Biol Chem, 274 (25), 18081-6
DOI 10.1074/jbc.274.25.18081, PubMed 10364261
Kraggerud SM, Berner A, Bryne M, Pettersen EO, Fossa SD (1999)
Spermatocytic seminoma as compared to classical seminoma: an immunohistochemical and DNA flow cytometric study
APMIS, 107 (3), 297-302
DOI 10.1111/j.1699-0463.1999.tb01557.x, PubMed 10223302
Lyngstadaas A, Løbner-Olesen A, Grelland E, Boye E (1999)
The gene for 2-phosphoglycolate phosphatase (gph) in Escherichia coli is located in the same operon as dam and at least five other diverse genes
Biochim Biophys Acta, 1472 (1-2), 376-84
DOI 10.1016/s0304-4165(99)00146-4, PubMed 10572959
Løbner-Olesen A (1999)
Distribution of minichromosomes in individual Escherichia coli cells: implications for replication control
EMBO J, 18 (6), 1712-21
DOI 10.1093/emboj/18.6.1712, PubMed 10075940
Olsnes S (1999)
[The Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 119 (30), 4450
PubMed 10827478
Rodal SK, Skretting G, Garred O, Vilhardt F, van Deurs B, Sandvig K (1999)
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
Mol Biol Cell, 10 (4), 961-74
DOI 10.1091/mbc.10.4.961, PubMed 10198050
Sandvig K, van Deurs B (1999)
Endocytosis and intracellular transport of ricin: recent discoveries
FEBS Lett, 452 (1-2), 67-70
DOI 10.1016/s0014-5793(99)00529-3, PubMed 10376680
Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1999)
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
DOI 10.1074/jbc.274.41.28857, PubMed 10506127
Skretting G, Torgersen ML, van Deurs B, Sandvig K (1999)
Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
J Cell Sci, 112 ( Pt 22), 3899-909
DOI 10.1242/jcs.112.22.3899, PubMed 10547351
Stenmark H, Aasland R (1999)
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
DOI 10.1242/jcs.112.23.4175, PubMed 10564636
Synnes M, Prydz K, Løvdal T, Brech A, Berg T (1999)
Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes
Biochim Biophys Acta, 1421 (2), 317-28
DOI 10.1016/s0005-2736(99)00134-0, PubMed 10518701
Torheim NK, Skarstad K (1999)
Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC
EMBO J, 18 (17), 4882-8
DOI 10.1093/emboj/18.17.4882, PubMed 10469666
Vilhardt F, Nielsen M, Sandvig K, van Deurs B (1999)
Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
Mol Biol Cell, 10 (1), 179-95
DOI 10.1091/mbc.10.1.179, PubMed 9880335
Wesche J, Rapak A, Olsnes S (1999)
Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
J Biol Chem, 274 (48), 34443-9
DOI 10.1074/jbc.274.48.34443, PubMed 10567425
Wiedłocha A (1999)
Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
PubMed 10604235
Yuan W, Stromhaug PE, Dunn WA (1999)
Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein
Mol Biol Cell, 10 (5), 1353-66
DOI 10.1091/mbc.10.5.1353, PubMed 10233149

Publications 1998

Amellem O, Sandvik JA, Stokke T, Pettersen EO (1998)
The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein
Br J Cancer, 77 (6), 862-72
DOI 10.1038/bjc.1998.143, PubMed 9528826
Asai T, Bates DB, Boye E, Kogoma T (1998)
Are minichromosomes valid model systems for DNA replication control? Lessons learned from Escherichia coli
Mol Microbiol, 29 (3), 671-5
DOI 10.1046/j.1365-2958.1998.00901.x, PubMed 9723907
Berg TO, Fengsrud M, Strømhaug PE, Berg T, Seglen PO (1998)
Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes
J Biol Chem, 273 (34), 21883-92
DOI 10.1074/jbc.273.34.21883, PubMed 9705327
Bernander R, Stokke T, Boye E (1998)
Flow cytometry of bacterial cells: comparison between different flow cytometers and different DNA stains
Cytometry, 31 (1), 29-36
DOI 10.1002/(sici)1097-0320(19980101)31:1<29::aid-cyto4>3.0.co;2-e, PubMed 9450522
Drolsum L, Haaskjold E, Sandvig K (1998)
Phacoemulsification in eyes with pseudoexfoliation
J Cataract Refract Surg, 24 (6), 787-92
DOI 10.1016/s0886-3350(98)80132-6, PubMed 9642589
Falnes PO, Olsnes S (1998)
Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway
EMBO J, 17 (2), 615-25
DOI 10.1093/emboj/17.2.615, PubMed 9430652
Frønsdal K, Engedal N, Slagsvold T, Saatcioglu F (1998)
CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
J Biol Chem, 273 (48), 31853-9
DOI 10.1074/jbc.273.48.31853, PubMed 9822653
Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
DOI 10.1038/28767, PubMed 9697764
Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M (1998)
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
DOI 10.1093/emboj/17.7.1930, PubMed 9524116
Grzelak I, Zaleska M, Olszewski WL (1998)
Blood transfusions downregulate hematopoiesis and subsequently downregulate the immune response
Transfusion, 38 (11-12), 1104-14
DOI 10.1046/j.1537-2995.1998.38111299056323.x, PubMed 9838944
Janson IM, Toomik R, O'Farrell F, Ek P (1998)
KDEL motif interacts with a specific sequence in mammalian erd2 receptor
Biochem Biophys Res Commun, 247 (2), 447-51
DOI 10.1006/bbrc.1998.8809, PubMed 9642148
Klingenberg O, Widlocha A, Rapak A, Muñoz R, Falnes P, Olsnes S (1998)
Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
J Biol Chem, 273 (18), 11164-72
DOI 10.1074/jbc.273.18.11164, PubMed 9556604
Kolpakova E, Wiedłocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1) (Pt 1), 213-22
DOI 10.1042/bj3360213, PubMed 9806903
Koritzinsky M, Furre T, Amellem O, Pettersen EO (1998)
Survival of synchronized human NHIK 3025 cells irradiated aerobically following a prolonged treatment with extremely hypoxic conditions
Int J Radiat Biol, 74 (4), 491-500
DOI 10.1080/095530098141366, PubMed 9798960
Kovács AL, Gordon PB, Grotterød EM, Seglen PO (1998)
Inhibition of hepatocytic autophagy by adenosine, adenosine analogs and AMP
Biol Chem, 379 (11), 1341-7
DOI 10.1515/bchm.1998.379.11.1341, PubMed 9865607
Llorente A, Rapak A, Schmid SL, van Deurs B, Sandvig K (1998)
Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
J Cell Biol, 140 (3), 553-63
DOI 10.1083/jcb.140.3.553, PubMed 9456316
Llorente A, van Deurs B, Sandvig K (1998)
Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
FEBS Lett, 431 (2), 200-4
DOI 10.1016/s0014-5793(98)00754-6, PubMed 9708902
Loukianov EV, Loukianova T, Wiedlocha A, Olsnes S (1998)
Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
Gene, 212 (1), 1-4
DOI 10.1016/s0378-1119(98)00139-5, PubMed 9661657
Lyngstadaas A, Sprenger GA, Boye E (1998)
Impaired growth of an Escherichia coli rpe mutant lacking ribulose-5-phosphate epimerase activity
Biochim Biophys Acta, 1381 (3), 319-30
DOI 10.1016/s0304-4165(98)00046-4, PubMed 9729441
Marcinkowska E, Wiedlocha A, Radzikowski C (1998)
Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
Anticancer Res, 18 (5A), 3507-14
PubMed 9858932
Mathiesen RH, Mo F, Eikenes A, Nyborg T, Larsen HB (1998)
Existence of two crystal structures of the complex alpha-D-glucose center dot NaCl center dot H2O (2 : 1 : 1) verified by three-beam diffraction experiments
Acta Crystallogr. Sect. A, 54, 338-347
DOI 10.1107/S0108767397018849
Olsnes S (1998)
Shiga and Shiga-like toxins
RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 143-153
Rundén E, Seglen PO, Haug FM, Ottersen OP, Wieloch T, Shamloo M, Laake JH (1998)
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism
J Neurosci, 18 (18), 7296-305
DOI 10.1523/JNEUROSCI.18-18-07296.1998, PubMed 9736650
Samari HR, Seglen PO (1998)
Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase
J Biol Chem, 273 (37), 23758-63
DOI 10.1074/jbc.273.37.23758, PubMed 9726984
Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
DOI 10.1016/S0171-9335(98)80116-7, PubMed 9587053
Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
DOI 10.1038/28879, PubMed 9697774
Strømhaug PE, Berg TO, Fengsrud M, Seglen PO (1998)
Purification and characterization of autophagosomes from rat hepatocytes
Biochem J, 335 ( Pt 2) (Pt 2), 217-24
DOI 10.1042/bj3350217, PubMed 9761717
Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (1998)
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
DOI 10.1093/emboj/17.7.1941, PubMed 9524117
Vogel U, Sandvig K, van Deurs B (1998)
Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
J Cell Sci, 111 ( Pt 6), 825-32
DOI 10.1242/jcs.111.6.825, PubMed 9472010
Waite RL, Sentry JW, Stenmark H, Toh BH (1998)
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
DOI 10.1006/clin.1997.4455, PubMed 9434799
Wesche J, Elliott JL, Falnes PO, Olsnes S, Collier RJ (1998)
Characterization of membrane translocation by anthrax protective antigen
Biochemistry, 37 (45), 15737-46
DOI 10.1021/bi981436i, PubMed 9843379
Wiedłocha A (1998)
Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
PubMed 9883312
Wold S, Boye E, Slater S, Kleckner N, Skarstad K (1998)
Effects of purified SeqA protein on oriC-dependent DNA replication in vitro
EMBO J, 17 (14), 4158-65
DOI 10.1093/emboj/17.14.4158, PubMed 9670030
Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C (1998)
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
DOI 10.1083/jcb.140.5.1039, PubMed 9490718
Zalecki P, Radzikowski C, Olsnes S, Wiedłocha A (1998)
Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
Exp Cell Res, 244 (1), 61-70
DOI 10.1006/excr.1998.4187, PubMed 9770349

Publications 1997

Amellem O, Stokke T, Sandvik JA, Smedshammer L, Pettersen EO (1997)
Hypoxia-induced apoptosis in human cells with normal p53 status and function, without any alteration in the nuclear protein level
Exp Cell Res, 232 (2), 361-70
DOI 10.1006/excr.1997.3497, PubMed 9168813
Bates DB, Boye E, Asai T, Kogoma T (1997)
The absence of effect of gid or mioC transcription on the initiation of chromosomal replication in Escherichia coli
Proc Natl Acad Sci U S A, 94 (23), 12497-502
DOI 10.1073/pnas.94.23.12497, PubMed 9356478
Carlson CR, Grallert B, Bernander R, Stokke T, Boye E (1997)
Measurement of nuclear DNA content in fission yeast by flow cytometry
Yeast, 13 (14), 1329-35
DOI 10.1002/(SICI)1097-0061(199711)13:14<1329::AID-YEA185>3.0.CO;2-M, PubMed 9392077
D'Arrigo A, Bucci C, Toh BH, Stenmark H (1997)
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016
Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
DOI 10.1074/jbc.272.17.11414, PubMed 9111051
Grzelak I, Zaleska M, Olszewski WL (1997)
Immune response after syngeneic and allogeneic blood cell transplantation
Transplant Proc, 29 (4), 2181-2
DOI 10.1016/s0041-1345(97)00283-2, PubMed 9193579
Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M (1997)
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
DOI 10.1016/s0092-8674(00)80380-3, PubMed 9323142
Kraggerud SM, Jacobsen KD, Berner A, Stokke T, Holm R, Smedshammer L, Børresen-Dale AL, Fosså SD (1997)
A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
Pathol Res Pract, 193 (7), 471-8
DOI 10.1016/s0344-0338(97)80099-4, PubMed 9342752
Lanzrein M, Falnes PO, Sand O, Olsnes S (1997)
Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes
J Membr Biol, 156 (2), 141-8
DOI 10.1007/s002329900196, PubMed 9075645
Lemichez E, Bomsel M, Devilliers G, vanderSpek J, Murphy JR, Lukianov EV, Olsnes S, Boquet P (1997)
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
Mol Microbiol, 23 (3), 445-57
DOI 10.1111/j.1365-2958.1997.tb02669.x, PubMed 9044279
Loukianov E, Loukianova T, Wiedlocha A, Olsnes S (1997)
Expression of mRNA for a short form of heparin-binding EGF-like growth factor
Gene, 195 (1), 81-6
DOI 10.1016/s0378-1119(97)00161-3, PubMed 9300824
Marcinkowska E, Wiedłocha A, Radzikowski C (1997)
1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
Biochem Biophys Res Commun, 241 (2), 419-26
DOI 10.1006/bbrc.1997.7832, PubMed 9425286
Muñoz R, Klingenberg O, Wiedłocha A, Rapak A, Falnes PO, Olsnes S (1997)
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
DOI 10.1038/sj.onc.1201226, PubMed 9247306
Olkkonen VM, Stenmark H (1997)
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
DOI 10.1016/s0074-7696(08)61608-3, PubMed 9394917
Polesskaia AN, Garred O, Olsnes S, Kozlov IuV (1997)
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098
Polesskaya AN, Garred O, Olsnes S, Kozlov YV (1997)
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447
Rapak A, Falnes PO, Olsnes S (1997)
Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
Proc Natl Acad Sci U S A, 94 (8), 3783-8
DOI 10.1073/pnas.94.8.3783, PubMed 9108055
Sandvig K, Garred O, van Deurs B (1997)
Intracellular transport and processing of protein toxins produced by enteric bacteria
Adv Exp Med Biol, 412, 225-32
DOI 10.1007/978-1-4899-1828-4_34, PubMed 9192018
Seglen PO (1997)
DNA ploidy and autophagic protein degradation as determinants of hepatocellular growth and survival
Cell Biol Toxicol, 13 (4-5), 301-15
DOI 10.1023/a:1007487425047, PubMed 9298250
Strømhaug PE, Berg TO, Gjøen T, Seglen PO (1997)
Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes
Eur J Cell Biol, 73 (1), 28-39
PubMed 9174669
Wiedłocha A (1997)
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
PubMed 9437495

Publications 1996

Allen ED, Burton RL, Webber SK, Haaskjold E, Sandvig K, Jyrkkiö H, Leite E, Nyström A, Wollensak J (1996)
Comparison of a diffractive bifocal and a monofocal intraocular lens
J Cataract Refract Surg, 22 (4), 446-51
DOI 10.1016/s0886-3350(96)80040-x, PubMed 8733848
Amellem O, Stokke T, Sandvik JA, Pettersen EO (1996)
The retinoblastoma gene product is reversibly dephosphorylated and bound in the nucleus in S and G2 phases during hypoxic stress
Exp Cell Res, 227 (1), 106-15
DOI 10.1006/excr.1996.0255, PubMed 8806457
Berg T, Gudmundsen O, Brech A, Kjeken R, Gjøen T (1996)
Clathrin-dependent and clathrin-independent endocytosis in liver cells
Z Gastroenterol, 34 Suppl 3, 92-4
PubMed 8767476
Boye E, Stokke T, Kleckner N, Skarstad K (1996)
Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins
Proc Natl Acad Sci U S A, 93 (22), 12206-11
DOI 10.1073/pnas.93.22.12206, PubMed 8901558
Karlsen F, Kalantari M, Jenkins A, Pettersen E, Kristensen G, Holm R, Johansson B, Hagmar B (1996)
Use of multiple PCR primer sets for optimal detection of human papillomavirus
J Clin Microbiol, 34 (9), 2095-100
DOI 10.1128/jcm.34.9.2095-2100.1996, PubMed 8862564
Klingenberg O, Olsnes S (1996)
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
Biochem J, 313 ( Pt 2) (Pt 2), 647-53
DOI 10.1042/bj3130647, PubMed 8573105
Lanzrein M, Sand O, Olsnes S (1996)
GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity
EMBO J, 15 (4), 725-34
DOI 10.1002/j.1460-2075.1996.tb00408.x, PubMed 8631294
Llorente A, Garred O, Holm PK, Eker P, Jacobsen J, van Deurs B, Sandvig K (1996)
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
Exp Cell Res, 227 (2), 298-308
DOI 10.1006/excr.1996.0279, PubMed 8831568
Sandvig K, Garred O, van Deurs B (1996)
Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
Proc Natl Acad Sci U S A, 93 (22), 12339-43
DOI 10.1073/pnas.93.22.12339, PubMed 8901582
Sandvig K, Garred O, van Helvoort A, van Meer G, van Deurs B (1996)
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
Mol Biol Cell, 7 (9), 1391-404
DOI 10.1091/mbc.7.9.1391, PubMed 8885234
Sandvig K, van Deurs B (1996)
Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
Physiol Rev, 76 (4), 949-66
DOI 10.1152/physrev.1996.76.4.949, PubMed 8874490
Stenmark H, Aasland R, Toh BH, D'Arrigo A (1996)
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
DOI 10.1074/jbc.271.39.24048, PubMed 8798641
Tjelle TE, Brech A, Juvet LK, Griffiths G, Berg T (1996)
Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation
J Cell Sci, 109 ( Pt 12), 2905-14
DOI 10.1242/jcs.109.12.2905, PubMed 9013338
van Deurs B, Holm PK, Sandvig K (1996)
Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
Eur J Cell Biol, 69 (4), 343-50
PubMed 8741216
van Deurs B, von Bũlow F, Vilhardt F, Holm PK, Sandvig K (1996)
Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
J Cell Sci, 109 ( Pt 7), 1655-65
DOI 10.1242/jcs.109.7.1655, PubMed 8832388
Waldum HL, Osmundsen H, Olsnes S, Sand O (1996)
[The Anders Jahre medical awarad 1996]
Tidsskr Nor Laegeforen, 116 (23), 2804-6
PubMed 8928170
Wiedłocha A (1996)
Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
PubMed 9017159
Wiedłocha A, Falnes PO, Rapak A, Muñoz R, Klingenberg O, Olsnes S (1996)
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
DOI 10.1128/MCB.16.1.270, PubMed 8524304

Publications 1995

Barnett YA, Brennan LA, O'Farrell F, Hannigan BM (1995)
Oxidant-induced stress response in lymphoid cells
Biochem Mol Biol Int, 37 (2), 273-81
PubMed 8673010
ERIKSEN S, SAND O, LANZREIN M, SANDVIG K, OLSNES S (1995)
CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168
DOI 10.1016/S0966-842X(00)88912-X
Falnes PO, Olsnes S (1995)
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
J Biol Chem, 270 (35), 20787-93
DOI 10.1074/jbc.270.35.20787, PubMed 7657662
Falnes PO, Wiedłocha A, Rapak A, Olsnes S (1995)
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
Biochemistry, 34 (35), 11152-9
DOI 10.1021/bi00035a021, PubMed 7669773
Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
DOI 10.1006/excr.1995.1128, PubMed 7737376
Garred O, van Deurs B, Sandvig K (1995)
Furin-induced cleavage and activation of Shiga toxin
J Biol Chem, 270 (18), 10817-21
DOI 10.1074/jbc.270.18.10817, PubMed 7738018
Holen I, Gordon PB, Strømhaug PE, Berg TO, Fengsrud M, Brech A, Roos N, Berg T, Seglen PO (1995)
Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
Biochem J, 311 ( Pt 1) (Pt 1), 317-26
DOI 10.1042/bj3110317, PubMed 7575471
Holm PK, Eker P, Sandvig K, van Deurs B (1995)
Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
Exp Cell Res, 217 (1), 157-68
DOI 10.1006/excr.1995.1075, PubMed 7867714
Kjeken R, Brech A, Løvdal T, Roos N, Berg T (1995)
Involvement of early and late lysosomes in the degradation of mannosylated ligands by rat liver endothelial cells
Exp Cell Res, 216 (2), 290-8
DOI 10.1006/excr.1995.1037, PubMed 7843273
Lanzrein M, Garred O, Olsnes S, Sandvig K (1995)
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1) (Pt 1), 285-9
DOI 10.1042/bj3100285, PubMed 7646457
Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH (1995)
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
DOI 10.1074/jbc.270.22.13503, PubMed 7768953
Singer-Krüger B, Stenmark H, Zerial M (1995)
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
DOI 10.1242/jcs.108.11.3509, PubMed 8586662
Stenmark H, Vitale G, Ullrich O, Zerial M (1995)
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
Cell, 83 (3), 423-32
DOI 10.1016/0092-8674(95)90120-5, PubMed 8521472
Valdizan EM, Loukianov EV, Olsnes S (1995)
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor
J Biol Chem, 270 (28), 16879-85
DOI 10.1074/jbc.270.28.16879, PubMed 7622504
van Deurs B, Holm PK, Kayser L, Sandvig K (1995)
Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
Eur J Cell Biol, 66 (4), 309-23
PubMed 7544728
Vitale G, Alexandrov K, Ullrich O, Horiuchi H, Giner A, Dobson C, Baykova O, Gournier H, Stenmark H, Zerial M (1995)
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
DOI 10.1101/sqb.1995.060.01.024, PubMed 8824393
Wiedłocha A, Falnes PO, Rapak A, Klingenberg O, Muñoz R, Olsnes S (1995)
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
DOI 10.1074/jbc.270.51.30680, PubMed 8530506
Aas AT, Tønnessen TI, Brun A, Salford LG (1995)
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
J Neurooncol, 24 (2), 171-80
DOI 10.1007/BF01078487, PubMed 7562004

Publications 1994

de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG (1994)
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
DOI 10.1016/0896-6273(94)90456-1, PubMed 8043272
Eker P, Holm PK, van Deurs B, Sandvig K (1994)
Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
J Biol Chem, 269 (28), 18607-15
PubMed 8034609
Eriksen S, Olsnes S, Sandvig K, Sand O (1994)
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
DOI 10.1002/j.1460-2075.1994.tb06765.x, PubMed 7523112
Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S (1994)
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
J Biol Chem, 269 (11), 8402-7
PubMed 8132565
Lanzrein M, Schlegel A, Kempf C (1994)
Entry and uncoating of enveloped viruses
Biochem J, 302 ( Pt 2) (Pt 2), 313-20
DOI 10.1042/bj3020313, PubMed 8092981
Madshus IH, Wiedlocha A, Sandvig K (1994)
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447
SANDVIG K, GARRED O, HOLM PK, VANDEURS B (1994)
ENTRY OF SHIGA TOXIN INTO CELLS
INT CONGR SER, 1072, 139-146
Sandvig K, Ryd M, Garred O, Schweda E, Holm PK, van Deurs B (1994)
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
J Cell Biol, 126 (1), 53-64
DOI 10.1083/jcb.126.1.53, PubMed 8027186
Sandvig K, van Deurs B (1994)
Endocytosis and intracellular sorting of ricin and Shiga toxin
FEBS Lett, 346 (1), 99-102
DOI 10.1016/0014-5793(94)00281-9, PubMed 8206167
Sandvig K, van Deurs B (1994)
Endocytosis without clathrin
Trends Cell Biol, 4 (8), 275-7
DOI 10.1016/0962-8924(94)90211-9, PubMed 14731589
SANDVIG K, VANDEURS B (1994)
ENTRY OF SHIGA TOXIN INTO CELLS
ZBL BAKT S, 24, 365-374
Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo JS, Gallwitz D, Zerial M (1994)
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
DOI 10.1083/jcb.125.2.283, PubMed 8163546
Wiedłocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
DOI 10.1016/0092-8674(94)90381-6, PubMed 7511061

Publications 1993

Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
DOI 10.1021/bi00052a012, PubMed 8418864
Aullo P, Giry M, Olsnes S, Popoff MR, Kocks C, Boquet P (1993)
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly
EMBO J, 12 (3), 921-31
DOI 10.1002/j.1460-2075.1993.tb05733.x, PubMed 8458345
Banning DP, O'Farrell F, Gooderham NJ (1993)
Activation of the food derived carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat pleural cavity inflammatory cells
Carcinogenesis, 14 (12), 2457-62
DOI 10.1093/carcin/14.12.2457, PubMed 8269612
BERG T, BRECH A, KJEKEN R, ROOS N (1993)
PRELYSOSOMAL DEGRADATION IN RAT-LIVER ENDOTHELIAL-CELLS
CELLS OF THE HEPATIC SINUSOID, VOL 4, 426-430
Esbensen QY, Falnes PO, Olsnes S, Madshus IH (1993)
Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
Biochem J, 294 ( Pt 3) (Pt 3), 663-6
DOI 10.1042/bj2940663, PubMed 8379922
Hansen SH, Sandvig K, van Deurs B (1993)
Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
J Cell Biol, 123 (1), 89-97
DOI 10.1083/jcb.123.1.89, PubMed 8408209
Hansen SH, Sandvig K, van Deurs B (1993)
Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
J Cell Biol, 121 (1), 61-72
DOI 10.1083/jcb.121.1.61, PubMed 8458873
Holm PK, Hansen SH, Sandvig K, van Deurs B (1993)
Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
Eur J Cell Biol, 62 (2), 362-71
PubMed 7925492
Loukianov EV, Olsnes S (1993)
New cloning opportunities with the use of noncomplementary SfiI adaptors
Biotechniques, 15 (6), 980-2
PubMed 8292350
Ludt J, Sandvig K, Olsnes S (1993)
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
DOI 10.1007/BF00232750, PubMed 8411117
Melby EL, Jacobsen J, Olsnes S, Sandvig K (1993)
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493
Moskaug JO, Prydz K, Olsnes S (1993)
Rapid cellular removal of a membrane-inserted foreign polypeptide
Biochem J, 291 ( Pt 2) (Pt 2), 473-7
DOI 10.1042/bj2910473, PubMed 8484728
Olsnes S, van Deurs B, Sandvig K (1993)
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
DOI 10.1007/BF00189373, PubMed 8392658
Ottestad L, Andersen TI, Nesland JM, Skrede M, Tveit KM, Nustad K, Børresen AL (1993)
Amplification of c-erbB-2, int-2 and c-myc genes in node-negative breast carcinomas. Relationship to prognosis
Acta Oncol, 32 (3), 289-94
DOI 10.3109/02841869309093597, PubMed 8100712
Ottestad L, Pettersen EO, Nesland JM, Hannisdal E, Fosså SD, Tveit KM (1993)
Flow cytometric DNA analysis as prognostic factor in human breast carcinoma
Pathol Res Pract, 189 (4), 405-10
DOI 10.1016/S0344-0338(11)80327-4, PubMed 8351241
Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, Van Deurs B (1993)
Entry of Shiga toxin into cells
Zentralbl Bakteriol, 278 (2-3), 296-305
DOI 10.1016/s0934-8840(11)80846-7, PubMed 8347933
Sandvig K, Garred O, Holm PK, van Deurs B (1993)
Endocytosis and intracellular transport of protein toxins
Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
DOI 10.1042/bst0210707, PubMed 8224494
Ullrich O, Stenmark H, Alexandrov K, Huber LA, Kaibuchi K, Sasaki T, Takai Y, Zerial M (1993)
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690
van Deurs B, Holm PK, Kayser L, Sandvig K, Hansen SH (1993)
Multivesicular bodies in HEp-2 cells are maturing endosomes
Eur J Cell Biol, 61 (2), 208-24
PubMed 8223712
van Deurs B, Holm PK, Sandvig K, Hansen SH (1993)
Are caveolae involved in clathrin-independent endocytosis?
Trends Cell Biol, 3 (8), 249-51
DOI 10.1016/0962-8924(93)90045-3, PubMed 14731741
Zerial M, Stenmark H (1993)
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
DOI 10.1016/0955-0674(93)90130-i, PubMed 8257602

Publications 1992

Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320
Hansen SH, Sandvig K, van Deurs B (1992)
Internalization efficiency of the transferrin receptor
Exp Cell Res, 199 (1), 19-28
DOI 10.1016/0014-4827(92)90457-j, PubMed 1735458
Jonas L, Walzel H, Bremer H, Wiedlocha A (1992)
Comparative studies on internalization of gold labelled mistletoe lectin I (MLI), its subunits, and of an immunotoxin into mouse L 1210V leukemia cells
Acta Histochem, 92 (1), 46-53
DOI 10.1016/S0065-1281(11)80140-6, PubMed 1580141
Madshus IH, Olsnes S, Stenmark H (1992)
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
DOI 10.1128/iai.60.8.3296-3302.1992, PubMed 1639497
Madshus IH, Stenmark H (1992)
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
DOI 10.1007/978-3-642-76966-5_1, PubMed 1378368
O'Brien AD, Tesh VL, Donohue-Rolfe A, Jackson MP, Olsnes S, Sandvig K, Lindberg AA, Keusch GT (1992)
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
DOI 10.1007/978-3-642-77238-2_4, PubMed 1324134
Olsnes S, Frankel AE (1992)
Genetically engineered toxins in perspective
Targeted Diagn Ther, 7, 465-77
PubMed 1633307
Paprocka M, Wiedłocha A, Walzel H, Radzikowski C (1992)
The activity of two immunotoxins composed of monoclonal antibody MoAb-16 and A-chain of ricin (MoAb-16-RTA) or A-chain of mistletoe lectin I (MoAb-16-MLIA)
Arch Immunol Ther Exp (Warsz), 40 (3-4), 223-7
PubMed 1300987
Prydz K, Hansen SH, Sandvig K, van Deurs B (1992)
Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells
J Cell Biol, 119 (2), 259-72
DOI 10.1083/jcb.119.2.259, PubMed 1400572
Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
Protein toxins: mode of action and cell entry
Biochem Soc Trans, 20 (4), 724-7
DOI 10.1042/bst0200724, PubMed 1487049
Sandvig K, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
Nature, 358 (6386), 510-2
DOI 10.1038/358510a0, PubMed 1641040
Sandvig K, van Deurs B (1992)
Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
Exp Cell Res, 200 (2), 253-62
DOI 10.1016/0014-4827(92)90171-4, PubMed 1572394
Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3) (Pt 3), 619-25
DOI 10.1042/bj2810619, PubMed 1536643
Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382
Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S (1992)
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
EMBO J, 11 (13), 4835-42
DOI 10.1002/j.1460-2075.1992.tb05589.x, PubMed 1281450

Publications 1991

Erikstein BK, Smeland EB, Blomhoff HK, Funderud S, Prydz K, Lesslauer W, Espevik T (1991)
Independent regulation of 55-kDa and 75-kDa tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes
Eur J Immunol, 21 (4), 1033-7
DOI 10.1002/eji.1830210426, PubMed 1850359
Hansen SH, Sandvig K, van Deurs B (1991)
The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
J Cell Biol, 113 (4), 731-41
DOI 10.1083/jcb.113.4.731, PubMed 1673969
Jacobsen AB, Tveit KM, Pettersen EO, Fossa SD, Ous S (1991)
Colony formation in urinary bladder carcinoma. Relationship to DNA flow cytometry, stage and histopathology
Anticancer Res, 11 (2), 777-81
PubMed 2064333
Kjønniksen I, Høifødt HK, Pihl A, Fodstad O (1991)
Different metastasis patterns of a human melanoma cell line in nude mice and rats: influence of microenvironment
J Natl Cancer Inst, 83 (14), 1020-4
DOI 10.1093/jnci/83.14.1020, PubMed 2072409
Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
DOI 10.1007/BF01871417, PubMed 2046087
Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632
Melby EL, Prydz K, Olsnes S, Sandvig K (1991)
Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
J Cell Biochem, 47 (3), 251-60
DOI 10.1002/jcb.240470311, PubMed 1791187
Moskaug JO, Stenmark H, Olsnes S (1991)
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012
Nesland JM, Ottestad L, Heikilla R, Holm R, Tveit K, Børresen AL (1991)
C-erbB-2 protein and neuroendocrine expression in breast carcinomas
Anticancer Res, 11 (1), 161-7
PubMed 1673329
Olsnes S, Kozlov JV, van Deurs B, Sandvig K (1991)
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345
Sandvig K, Prydz K, Hansen SH, van Deurs B (1991)
Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
J Cell Biol, 115 (4), 971-81
DOI 10.1083/jcb.115.4.971, PubMed 1955466
Sandvig K, Prydz K, Ryd M, van Deurs B (1991)
Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
J Cell Biol, 113 (3), 553-62
DOI 10.1083/jcb.113.3.553, PubMed 1901867
Sandvig K, van Deurs B (1991)
Endocytosis without clathrin (a minireview)
Cell Biol Int Rep, 15 (1), 3-8
DOI 10.1016/0309-1651(91)90077-v, PubMed 1900741
Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
DOI 10.1083/jcb.113.5.1025, PubMed 2040642
Stenmark H, Olsnes S, Madshus IH (1991)
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
DOI 10.1111/j.1365-2958.1991.tb00730.x, PubMed 1646374
Storeng RT, Kjønniksen I, Pihl A, Haug E, Fodstad O (1991)
Athymic rats in preclinical immunodiagnostic studies
Anticancer Res, 11 (2), 649-55
PubMed 2064318
Wiedłocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131

Publications 1990

Børresen AL, Ottestad L, Gaustad A, Andersen TI, Heikkilä R, Jahnsen T, Tveit KM, Nesland JM (1990)
Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis
Br J Cancer, 62 (4), 585-90
DOI 10.1038/bjc.1990.334, PubMed 1977466
Kjønniksen I, Nesland JM, Pihl A, Fodstad O (1990)
Nude rat model for studying metastasis of human tumor cells to bone and bone marrow
J Natl Cancer Inst, 82 (5), 408-12
DOI 10.1093/jnci/82.5.408, PubMed 2304088
Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980
Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341
Paprocka M, Wiedlocha A, Radzikowski C (1990)
Mouse L1210V leukemia as a model to analyse efficiency of leukemic cell elimination by immunotoxin, antibody and complement, and cytostatic agents
In Vivo, 4 (3), 209-13
PubMed 2133264
Sandvig K, van Deurs B (1990)
Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
J Biol Chem, 265 (11), 6382-8
PubMed 1969411
Tønnessen TI, Sandvig K, Olsnes S (1990)
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
DOI 10.1152/ajpcell.1990.258.6.C1117, PubMed 2163200
Tønnessen TI, Aas AT, Ludt J, Blomhoff HK, Olsnes S (1990)
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
J Cell Physiol, 143 (1), 178-87
DOI 10.1002/jcp.1041430125, PubMed 2156872
van Deurs B, Hansen SH, Petersen OW, Melby EL, Sandvig K (1990)
Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
Eur J Cell Biol, 51 (1), 96-109
PubMed 2328741

Publications 1989

Eker P (1989)
Effects of epidermal growth factor, fibroblast growth factor, retinoic acid and serum on anchorage-dependent and anchorage-independent growth of HRRT cells
Eur J Cancer Clin Oncol, 25 (3), 499-504
DOI 10.1016/0277-5379(89)90263-0, PubMed 2784762
Hansen SH, Petersen OW, Sandvig K, Olsnes S, van Deurs B (1989)
Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
Exp Cell Res, 185 (2), 373-86
DOI 10.1016/0014-4827(89)90307-8, PubMed 2689197
Katnik I, Steuden I, Pupek M, Wiedłocha A, Dobryszycka W (1989)
Monoclonal antibodies against human haptoglobin
Hybridoma, 8 (5), 551-60
DOI 10.1089/hyb.1989.8.551, PubMed 2478448
Kjønniksen I, Storeng R, Pihl A, McLemore TL, Fodstad O (1989)
A human tumor lung metastasis model in athymic nude rats
Cancer Res, 49 (18), 5148-52
PubMed 2766284
KOTANSKA KM, HOLM R, OTTESTAD L, NESLAND JM (1989)
AN ULTRASTRUCTURAL-STUDY OF BENIGN AND MALIGNANT BREAST EPITHELIAL-CELLS - A SEARCH FOR TONOFILAMENTS
J. Submicrosc. Cytol. Pathol., 21 (3), 469-474
McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
DOI 10.1002/j.1460-2075.1989.tb08431.x, PubMed 2684631
Moskaug JO, Sandvig K, Olsnes S (1989)
Role of anions in low pH-induced translocation of diphtheria toxin
J Biol Chem, 264 (19), 11367-72
PubMed 2500440
Moskaug JO, Sletten K, Sandvig K, Olsnes S (1989)
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J Biol Chem, 264 (26), 15709-13
PubMed 2768283
Nenseter MS, Myklebost O, Blomhoff R, Drevon CA, Nilsson A, Norum KR, Berg T (1989)
Low-density-lipoprotein receptors in different rabbit liver cells
Biochem J, 261 (2), 587-93
DOI 10.1042/bj2610587, PubMed 2549976
Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677
Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882
OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751
Ottestad L, Tveit KM, Hannisdal E, Skrede M, Nesland JM, Gundersen S, Pihl A (1989)
Colony forming ability of human breast carcinomas: lack of prognostic significance
Br J Cancer, 60 (2), 216-9
DOI 10.1038/bjc.1989.254, PubMed 2765368
Radzikowski CZ, Steuden I, Wiedlocha A, Kieler J, Tromholt V (1989)
The Thomsen-Friedenreich antigen on human urothelial cell lines detectable by peanut lectin and monoclonal antibody raised against human glycophorin A
Anticancer Res, 9 (1), 103-7
PubMed 2650614
Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
J Cell Biol, 108 (4), 1331-43
DOI 10.1083/jcb.108.4.1331, PubMed 2564398
Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
Control of coated-pit function by cytoplasmic pH
Methods Cell Biol, 32, 365-82
DOI 10.1016/s0091-679x(08)61181-4, PubMed 2575206
Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538
Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
DOI 10.1016/0006-2952(89)90131-7, PubMed 2818647
Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970
van Deurs B, Petersen OW, Olsnes S, Sandvig K (1989)
The ways of endocytosis
Int Rev Cytol, 117, 131-77
DOI 10.1016/s0074-7696(08)61336-4, PubMed 2573583
van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460

Publications 1988

Bruland OS, Fodstad O, Stenwig AE, Pihl A (1988)
Expression and characteristics of a novel human osteosarcoma-associated cell surface antigen
Cancer Res, 48 (18), 5302-9
PubMed 2457439
Czerwiński M, Waśniowska K, Steuden I, Duk M, Wiedłocha A, Lisowska E (1988)
Degradation of the human erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3
Eur J Biochem, 174 (4), 647-54
DOI 10.1111/j.1432-1033.1988.tb14147.x, PubMed 2455637
Erikstein B, Nesland JM, Ottestad L, Lund E, Johannessen JV (1988)
Neuron specific enolase-positive breast carcinomas
Histol Histopathol, 3 (1), 97-102
PubMed 2980214
Fodstad O, Kjønniksen I, Aamdal S, Nesland JM, Boyd MR, Pihl A (1988)
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
Cancer Res, 48 (15), 4382-8
PubMed 3390834
Herz J, Hamann U, Rogne S, Myklebost O, Gausepohl H, Stanley KK (1988)
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
EMBO J, 7 (13), 4119-27
DOI 10.1002/j.1460-2075.1988.tb03306.x, PubMed 3266596
Holtskog R, Sandvig K, Olsnes S (1988)
Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
Oncology, 45 (3), 172-9
DOI 10.1159/000226557, PubMed 3368193
Madshus IH (1988)
Regulation of intracellular pH in eukaryotic cells
Biochem J, 250 (1), 1-8
DOI 10.1042/bj2500001, PubMed 2965576
Moskaug JO, Sandvig K, Olsnes S (1988)
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
J Biol Chem, 263 (5), 2518-25
PubMed 3339019
NESLAND JM, HOLM R, OTTESTAD L, KARLSEN KO, JOHANNESSEN JV (1988)
NEURO-ENDOCRINE ACTIVITY IN METASTATIC BREAST CARCINOMAS
APMIS, 96 2, 204-214
Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713
Olsnes S, Sandvig K (1988)
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634
Ottestad L, Tveit KM, Høifødt HK, Nesland JM, Vaage S, Høie J, Lund E, Pihl A (1988)
Cultivation of human breast carcinoma in soft agar. Experience with 237 fresh tumour specimens
Br J Cancer, 58 (1), 8-12
DOI 10.1038/bjc.1988.151, PubMed 3048354
Ottestad LO, Tveit KM, Nesland JM, Dybsjord I, Børmer O, Høie J, Pihl A (1988)
An immunocytochemical method for assaying oestrogen receptors in breast cancers. A comparison with the steroid binding assay
Histol Histopathol, 3 (3), 269-74
PubMed 2980233
Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517
Sandvig K, Olsnes S (1988)
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
J Biol Chem, 263 (25), 12352-9
PubMed 2457582
Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
Inhibition of endocytosis from coated pits by acidification of the cytosol
J Cell Biochem, 36 (1), 73-81
DOI 10.1002/jcb.240360108, PubMed 2893802
Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666
van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G (1988)
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
J Cell Biol, 106 (2), 253-67
DOI 10.1083/jcb.106.2.253, PubMed 2892843
Waśniowska K, Duk M, Steuden I, Czerwiński M, Wiedłocha A, Lisowska E (1988)
Two monoclonal antibodies recognizing different epitopes of blood group N antigen
Arch Immunol Ther Exp (Warsz), 36 (5), 623-32
PubMed 2478103

Publications 1987

Bruland O, Fodstad O, Skretting A, Pihl A (1987)
Selective localisation of two radiolabelled anti-sarcoma monoclonal antibodies in human osteosarcoma xenografts
Br J Cancer, 56 (1), 21-5
DOI 10.1038/bjc.1987.146, PubMed 3476143
Godal A, Fodstad O, Pihl A (1987)
Studies on the mechanism of action of abrin-9.2.27 immunotoxin in human melanoma cell lines
Cancer Res, 47 (23), 6243-7
PubMed 2445469
Gundersen S, Aamdal S, Fodstad O (1987)
Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
Br J Cancer, 55 (4), 433-5
DOI 10.1038/bjc.1987.85, PubMed 3580266
Hovig E, Winberg JO, Fodstad O, Brøgger A, Gedde-Dahl T (1987)
Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
Cancer Genet Cytogenet, 24 (2), 327-34
DOI 10.1016/0165-4608(87)90115-4, PubMed 2878716
Madshus IH, Olsnes S (1987)
Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
J Biol Chem, 262 (16), 7486-91
PubMed 3584123
Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
DOI 10.1002/jcp.1041310104, PubMed 3032992
Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
DOI 10.1002/jcp.1041310103, PubMed 3571337
Moskaug JO, Sandvig K, Olsnes S (1987)
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141
Olsnes S (1987)
Closing in on ricin action
Nature, 328 (6130), 474-5
DOI 10.1038/328474b0, PubMed 3614350
Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
DOI 10.1002/jcp.1041320203, PubMed 3624315
Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
DOI 10.1021/bi00384a019, PubMed 3606992
Sandvig K, Brown JE (1987)
Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
Infect Immun, 55 (2), 298-303
DOI 10.1128/iai.55.2.298-303.1987, PubMed 3542829
Sandvig K, Moskaug JO (1987)
Pseudomonas toxin binds triton X-114 at low pH
Biochem J, 245 (3), 899-901
DOI 10.1042/bj2450899, PubMed 3117052
Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
DOI 10.1083/jcb.105.2.679, PubMed 2887575
Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
DOI 10.1002/jcp.1041320202, PubMed 3624314
van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628
Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553

Publications 1986

Godal A, Bruland O, Haug E, Aas M, Fodstad O (1986)
Unexpected expression of the 250 kD melanoma-associated antigen in human sarcoma cells
Br J Cancer, 53 (6), 839-41
DOI 10.1038/bjc.1986.142, PubMed 3718838
Mustafa AS, Kvalheim G, Degre M, Godal T (1986)
Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
Infect Immun, 53 (3), 491-7
DOI 10.1128/iai.53.3.491-497.1986, PubMed 2427449
Olsnes S, Carvajal E, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976
Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100
Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101
Olsnes S, Tønnessen TI, Sandvig K (1986)
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
DOI 10.1083/jcb.102.3.967, PubMed 3949885
Sandvig K, Olsnes S (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015
SANDVIG K, TONNESSEN TI, SAND O, OLSNES S (1986)
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644
Sandvig K, Tønnessen TI, Olsnes S (1986)
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563
Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160
van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
DOI 10.1083/jcb.102.1.37, PubMed 3001103

Publications 1985

Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
DOI 10.1002/jcp.1041220205, PubMed 3844014
Madshus IH, Sandvig K, Olsnes S (1985)
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095
Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483
Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869
OLSNES S, SANDVIG K, MADSHUS IH, SUNDAN A (1985)
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191
Sandvig K, Olsnes S (1985)
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
DOI 10.1042/bj2280521, PubMed 2990449
Sandvig K, Sundan A, Olsnes S (1985)
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
DOI 10.1002/jcp.1041240110, PubMed 3930519
Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357
STIRPE F, BARBIERI L, ABBONDANZA A, FALASCA AI, BROWN ANF, SANDVIG K, OLSNES S, PIHL A (1985)
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595
van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159
Aamdal S, Fodstad O, Nesland JM, Pihl A (1985)
Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
Br J Cancer, 51 (3), 347-56
DOI 10.1038/bjc.1985.46, PubMed 3970811

Publications 1984

Ege T (1984)
Analysis of heterokaryons and progeny cell hybrids isolated in the absence and in the presence of selective media
Cell Biol Int Rep, 8 (7), 599-606
DOI 10.1016/0309-1651(84)90060-2, PubMed 6744432
Ege T (1984)
Phenotypes of cell hybrids formed by fusion of normal and Rous sarcoma virus transformed cells
Cell Biol Int Rep, 8 (7), 607-13
DOI 10.1016/0309-1651(84)90061-4, PubMed 6086159
Lindmo T, Davies C, Fodstad O, Morgan AC (1984)
Stable quantitative differences of antigen expression in human melanoma cells isolated by flow cytometric cell sorting
Int J Cancer, 34 (4), 507-12
DOI 10.1002/ijc.2910340413, PubMed 6386700
Lindmo T, Davies C, Rofstad EK, Fodstad O, Sundan A (1984)
Antigen expression in human melanoma cells in relation to growth conditions and cell-cycle distribution
Int J Cancer, 33 (2), 167-71
DOI 10.1002/ijc.2910330203, PubMed 6693198
Madshus IH, Olsnes S, Sandvig K (1984)
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049
Madshus IH, Olsnes S, Sandvig K (1984)
Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029
Madshus IH, Olsnes S, Sandvig K (1984)
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
DOI 10.1083/jcb.98.4.1194, PubMed 6325467
Sandvig K, Madshus IH, Olsnes S (1984)
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
DOI 10.1042/bj2190935, PubMed 6331401
Sandvig K, Olsnes S (1984)
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140
Sandvig K, Olsnes S (1984)
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
DOI 10.1002/jcp.1041190103, PubMed 6707104
Sandvig K, Sundan A, Olsnes S (1984)
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
DOI 10.1083/jcb.98.3.963, PubMed 6699094
Sundan A, Sandvig K, Olsnes S (1984)
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858
Sundan A, Sandvig K, Olsnes S (1984)
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
DOI 10.1002/jcp.1041190104, PubMed 6707099
Wibe E, Berg JP, Tveit KM, Nesland JM, Lunde S (1984)
Multicellular spheroids grown directly from human tumour material
Int J Cancer, 34 (1), 21-6
DOI 10.1002/ijc.2910340105, PubMed 6746116
Aamdal S, Fodstad O, Kaalhus O, Pihl A (1984)
Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
J Natl Cancer Inst, 73 (3), 743-52
PubMed 6590919

Publications 1983

Eiklid K, Olsnes S (1983)
Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin
J Immunol, 130 (1), 380-4
PubMed 6336624
Eiklid K, Olsnes S (1983)
Entry of Shigella dysenteriae toxin into HeLa cells
Infect Immun, 42 (2), 771-7
DOI 10.1128/iai.42.2.771-777.1983, PubMed 6358031
Sundan A, Sandvig K, Olsnes S (1983)
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763
Sundan A, Sandvig K, Olsnes S (1983)
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111

Publications 1982

Olsnes S, Haylett T, Sandvig K (1982)
The toxic lectin modeccin
Methods Enzymol, 83, 357-62
DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935
Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144
Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276
Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634
Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145
Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588

Publications 1981

Abraham AK, Vedeler A, Reistad R, Pihl A (1981)
Polypeptide synthesis by mitoplasts isolated from mouse liver
Exp Cell Res, 132 (2), 265-72
DOI 10.1016/0014-4827(81)90102-6, PubMed 7215445
Godal A, Olsnes S, Pihl A (1981)
Radioimmunoassays of abrin and ricin in blood
J Toxicol Environ Health, 8 (3), 409-17
DOI 10.1080/15287398109530079, PubMed 7345165
Olsnes S (1981)
Directing toxins to cancer cells
Nature, 290 (5802), 84
DOI 10.1038/290084a0, PubMed 7207602
Olsnes S, Pihl A (1981)
Chimeric toxins
Pharmacol Ther, 15 (3), 355-81
DOI 10.1016/0163-7258(81)90050-4, PubMed 7345440
Olsnes S, Reisbig R, Eiklid K (1981)
Subunit structure of Shigella cytotoxin
J Biol Chem, 256 (16), 8732-8
PubMed 7021550
Reisbig R, Olsnes S, Eiklid K (1981)
The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit
J Biol Chem, 256 (16), 8739-44
PubMed 6894922
Sandvig K, Olsnes S (1981)
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699
Sandvig K, Olsnes S (1981)
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
DOI 10.1042/bj1940821, PubMed 7306026

Publications 1980

Eiklid K, Olsnes S (1980)
Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells
J Recept Res, 1 (2), 199-213
DOI 10.3109/10799898009044098, PubMed 6895387
Eiklid K, Olsnes S, Pihl A (1980)
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
Exp Cell Res, 126 (2), 321-6
DOI 10.1016/0014-4827(80)90270-0, PubMed 7363949
Gonatas J, Stieber A, Olsnes S, Gonatas NK (1980)
Pathways involved in fluid phase and adsorptive endocytosis in neuroblastoma
J Cell Biol, 87 (3 Pt 1), 579-88
DOI 10.1083/jcb.87.3.579, PubMed 7462317
Olsnes S, Eiklid K (1980)
Isolation and characterization of Shigella shigae cytotoxin
J Biol Chem, 255 (1), 284-9
PubMed 7350160
Sandvig K (1980)
[Receptors for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
PubMed 6250247
Sandvig K (1980)
[Intracellular mediators for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (15), 1021-23
PubMed 6250248
Sandvig K, Olsnes S (1980)
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
DOI 10.1083/jcb.87.3.828, PubMed 7462324
Stirpe F, Olsnes S, Pihl A (1980)
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
J Biol Chem, 255 (14), 6947-53
PubMed 7391060
Tveit KM, Fodstad O, Brøgger A, Olsnes S (1980)
Human embryonal carcinoma grown in athymic mice and in vitro
Cancer Res, 40 (3), 949-53
PubMed 7471109
Tveit KM, Fodstad O, Johannessen JV, Olsnes S (1980)
A human melanoma cell line established from xenograft in athymic mice
Br J Cancer, 41 (5), 724-33
DOI 10.1038/bjc.1980.134, PubMed 7426299
Tveit KM, Fodstad O, Olsnes S, Pihl A (1980)
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
Int J Cancer, 26 (6), 717-22
DOI 10.1002/ijc.2910260604, PubMed 7216540

Publications 1979

Abraham AK, Olsnes S, Pihl A (1979)
Fidelity of protein synthesis in vitro is increased in the presence of spermidine
FEBS Lett, 101 (1), 93-6
DOI 10.1016/0014-5793(79)81302-2, PubMed 446744
Olsnes S, Abraham AK (1979)
Elongation-factor-2-induced sensitization of ribosomes to modeccin. Evidence for specific binding of elongation factor 2 to ribosomes in the absence of nucleotides
Eur J Biochem, 93 (3), 447-52
DOI 10.1111/j.1432-1033.1979.tb12842.x, PubMed 421687
Sandvig K, Olsnes S (1979)
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
DOI 10.1016/0014-4827(79)90439-7, PubMed 446525
Sandvig K, Olsnes S, Pihl A (1979)
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
DOI 10.1016/0006-291x(79)91284-1, PubMed 508328

Publications 1978

Olsnes S (1978)
Toxic and nontoxic lectins from Abrus precatorius
Methods Enzymol, 50, 323-30
DOI 10.1016/0076-6879(78)50036-0, PubMed 661585
Olsnes S (1978)
Ricin and ricinus agglutinin, toxic lectins from castor bean
Methods Enzymol, 50, 330-5
DOI 10.1016/0076-6879(78)50037-2, PubMed 661586
Olsnes S, Haylett T, Refsnes K (1978)
Purification and characterization of the highly toxic lectin modeccin
J Biol Chem, 253 (14), 5069-73
PubMed 97288
OLSNES S, PIHL A (1978)
ABRIN AND RICIN-2 TOXIC LECTINS
Trends Biochem.Sci., 3 (1), 7-10
DOI 10.1016/S0968-0004(78)92494-5
Olsnes S, Refsnes K (1978)
On the mechanism of toxin resistance in cell variants resistant to abrin and ricin
Eur J Biochem, 88 (1), 7-15
DOI 10.1111/j.1432-1033.1978.tb12417.x, PubMed 566668
Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
DOI 10.1002/jss.400090103, PubMed 732310
Olsnes S, Tveit KM (1978)
[Teratocarcinoma as a model system in studies of malignancy and differentiation]
Tidsskr Nor Laegeforen, 98 (22), 998-1001
PubMed 684708
Sandvig K (1978)
Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
FEBS Lett, 89 (2), 233-6
DOI 10.1016/0014-5793(78)80225-7, PubMed 658411
Sandvig K, Olsnes S, Pihl A (1978)
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847
Sandvig K, Olsnes S, Pihl A (1978)
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666
Sandvig K, Olsnes S, Pihl A (1978)
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792
Wibe E, Oftebro R, Christensen T, Laland SG, Pettersen EO, Lindmo T (1978)
Inhibitory effects of the new mitotic inhibitor 5-chloropyrimidin-2-one and of vincristine on human cells in vitro
Cancer Res, 38 (3), 560-5
PubMed 626961

Publications 1977

Benson SC (1977)
Correlation of inhibition of ribosomal GTPase and protein synthesis by abrin and ricin
Biochem Biophys Res Commun, 75 (4), 845-50
DOI 10.1016/0006-291x(77)91459-0, PubMed 193503
Fodstad O, Olsnes S (1977)
Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
Eur J Biochem, 74 (2), 209-15
DOI 10.1111/j.1432-1033.1977.tb11383.x, PubMed 856578
Fodstad O, Olsnes S, Pihl A (1977)
Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
Cancer Res, 37 (12), 4559-67
PubMed 922739
Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
DOI 10.1016/0006-291x(77)91130-5, PubMed 603653
Skorve J, Abraham AK, Olsnes S, Pihl A (1977)
Effect of abrin on peptide chain initiation
Eur J Biochem, 79 (2), 559-64
DOI 10.1111/j.1432-1033.1977.tb11840.x, PubMed 243461

Publications 1976

Fernandez-Puentes C, Benson S, Olsnes S, Pihl A (1976)
Protective effect of elongation factor 2 on the inactivation of ribosomes by the toxic lectins abrin and ricin
Eur J Biochem, 64 (2), 437-43
DOI 10.1111/j.1432-1033.1976.tb10320.x, PubMed 1278169
Fodstad O, Olsnes S, Pihl A (1976)
Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
Br J Cancer, 34 (4), 418-25
DOI 10.1038/bjc.1976.187, PubMed 974006
OLSNES S (1976)
ABRIN AND RICIN - STRUCTURE AND MECHANISM OF ACTION OF 2 TOXIC LECTINS
Bull. Inst. Pasteur, 74 (1), 85-99
Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
J Biol Chem, 251 (13), 3985-92
PubMed 932017
Sandvig K, Olsnes S, Pihl A (1976)
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
J Biol Chem, 251 (13), 3977-84
PubMed 6468

Publications 1975

Benson S, Olsnes S, Pihl A, Skorve J, Abraham AK (1975)
On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit
Eur J Biochem, 59 (2), 573-80
DOI 10.1111/j.1432-1033.1975.tb02484.x, PubMed 128455
Closs O, Saltvedt E, Olsnes S (1975)
Stimulation of human lymphocytes by galactose-specific abrus and ricinus lectins
J Immunol, 115 (4), 1045-8
PubMed 1176765
HARBOE M, SALTVEDT E, CLOSS O, OLSNES S (1975)
INTERACTIONS BETWEEN RICINUS AGGLUTININ AND HUMAN PLASMA-PROTEINS
Scand. J. Immunol. (2), 125-134
Kozlov JV, Olsnes S, Brogger A, Pihl A (1975)
Cleavage of adenovirus-5 DNA by an endonuclease from Haemophilus parainfluenzae
FEBS Lett, 57 (2), 153-7
DOI 10.1016/0014-5793(75)80705-8, PubMed 1175785
Olsnes S, Fernandez-Puentes C, Carrasco L, Vazquez D (1975)
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
Eur J Biochem, 60 (1), 281-8
DOI 10.1111/j.1432-1033.1975.tb21001.x, PubMed 1204642
Olsnes S, Refsnes K, Christensen TB, Pihl A (1975)
Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis
Biochim Biophys Acta, 405 (1), 1-10
DOI 10.1016/0005-2795(75)90308-6, PubMed 1174560
Olsnes S, Saltvedt E (1975)
Conformation-dependent antigenic determinants in the toxic lectin ricin
J Immunol, 114 (6), 1743-8
PubMed 47877
Saltvedt E, Harboe M, Følling I, Olsnes S (1975)
Interactions between ricinus agglutinin and human IgM and IgG
Scand J Immunol, 4 (3), 287-94
DOI 10.1111/j.1365-3083.1975.tb02628.x, PubMed 1080291

Publications 1974

Olsnes S, Pappenheimer AM, Meren R (1974)
Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
J Immunol, 113 (3), 842-7
PubMed 4414071
Olsnes S, Pihl A (1974)
Clinical significance of estrogen receptors in human breast cancer
Biomedicine, 20 (6), 377-83
PubMed 4376029
Olsnes S, Refsnes K, Pihl A (1974)
Mechanism of action of the toxic lectins abrin and ricin
Nature, 249 (458), 627-31
DOI 10.1038/249627a0, PubMed 4857870
Olsnes S, Saltvedt E, Pihl A (1974)
Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ricinus communis
J Biol Chem, 249 (3), 803-10
PubMed 4811904
Pappenheimer AM, Olsnes S, Harper AA (1974)
Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
J Immunol, 113 (3), 835-41
PubMed 4213214
Refsnes K, Olsnes S, Pihl A (1974)
On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells
J Biol Chem, 249 (11), 3557-62
PubMed 4208663
REFSNES K, OLSNES S, PIHL A (1974)
TOXIC PROTEINS ABRIN AND RICIN - STUDIES OF THEIR BINDING TO AND ENTRY INTO EHRLICH ASCITES-CELLS
J. Biol. Chem., 249 (11), 3557-3562

Publications 1973

Olsnes S (1973)
[Gene activation and mRNA synthesis in higher organisms]
Tidsskr Nor Laegeforen, 93 (16), 1230-5
PubMed 4356591
Olsnes S (1973)
[Diphtheria toxin--a specific inhibitor of protein synthesis]
Tidsskr Nor Laegeforen, 93 (4), 223-7
PubMed 4691026
Olsnes S, Heiberg R, Pihl A (1973)
Inactivation of eucaryotic ribosomes by the toxic plant proteins abrin and ricin
Mol Biol Rep, 1 (1), 15-20
DOI 10.1007/BF00357400, PubMed 24197425
Olsnes S, Pihl A (1973)
Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains
Eur J Biochem, 35 (1), 179-85
DOI 10.1111/j.1432-1033.1973.tb02823.x, PubMed 4123356
Olsnes S, Pihl A (1973)
Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
Biochemistry, 12 (16), 3121-6
DOI 10.1021/bi00740a028, PubMed 4730499
Spaeren U, Olsnes S, Brennhovd I, Efskind J, Pihl A (1973)
Content of estrogen receptors in human breast cancer
Eur J Cancer (1965), 9 (5), 353-7
DOI 10.1016/0014-2964(73)90050-9, PubMed 4355726

Publications 1972

Birkeland H, Bottolfsen K (1972)
[Iridocyclitis with juvenile rheumatoid arthritis]
Tidsskr Nor Laegeforen, 12 (13), 922-3
PubMed 5063957
Heiberg R, Spaeren U, Olsnes S, Pihl A (1972)
Binding of rat liver ribosomes to nuclear complementary RNA
Biochim Biophys Acta, 281 (2), 270-6
DOI 10.1016/0005-2787(72)90179-7, PubMed 4629425
Lukanidin EM, Olsnes S, Pihl A (1972)
Antigenic difference between informofers and protein bound to polyribosomal mRNA from rat liver
Nat New Biol, 240 (98), 90-2
DOI 10.1038/newbio240090a0, PubMed 4117892
Olsnes S (1972)
Toxic proteins inhibiting protein synthesis
Naturwissenschaften, 59 (11), 497-502
DOI 10.1007/BF00609814, PubMed 4657651
Olsnes S, Heiberg R, Pihl A (1972)
Deoxycholate-induced release of monosomes from rat liver polyribosomes
Biochim Biophys Acta, 272 (1), 75-80
DOI 10.1016/0005-2787(72)90035-4, PubMed 5043716
Olsnes S, Pihl A (1972)
Inhibition of peptide chain elongation
Nature, 238 (5365), 459-61
DOI 10.1038/238459a0, PubMed 4561855
Olsnes S, Pihl A (1972)
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system
FEBS Lett, 28 (1), 48-50
DOI 10.1016/0014-5793(72)80674-4, PubMed 4646874
Olsnes S, Pihl A (1972)
Possible function of the protein bound to nuclear complementary RNA
FEBS Lett, 20 (2), 181-183
DOI 10.1016/0014-5793(72)80788-9, PubMed 11946410
Olsnes S, Pihl A (1972)
Ricin - a potent inhibitor of protein synthesis
FEBS Lett, 20 (3), 327-329
DOI 10.1016/0014-5793(72)80098-x, PubMed 11946449
Olsnes S, Spaeren U, Heiberg R, Pihl A (1972)
Protein synthesis in the presence of non-ionic detergents in a cell-free system from rabbit reticulocytes
Biochem J, 130 (1), 297-9
DOI 10.1042/bj1300297, PubMed 4655435
Spaeren U, Olsnes S, Pihl A (1972)
Translation of mouse globin mRNA by isolated ribosomal subunits from rabbit reticulocytes
Biochim Biophys Acta, 272 (4), 663-6
DOI 10.1016/0005-2787(72)90525-4, PubMed 5050924

Publications 1971

Heiberg R, Olsnes S, Pihl A (1971)
On the mechanism of the inhibiting effect of aurin tricarboxylic acid on the binding of ribosomes to ribonucleic acids
FEBS Lett, 18 (1), 169-171
DOI 10.1016/0014-5793(71)80436-2, PubMed 11946112
Olsnes S (1971)
Further studies on the protein bound to the messenger RNA in mammalian polysomes
Eur J Biochem, 23 (3), 557-63
DOI 10.1111/j.1432-1033.1971.tb01654.x, PubMed 5003111
Olsnes S (1971)
Evidence that protein is bound to the rapidly labelled RNA in polyribosomes in vivo
Eur J Biochem, 23 (2), 248-52
DOI 10.1111/j.1432-1033.1971.tb01615.x, PubMed 5003205
Olsnes S (1971)
Characterization of the complex containing rapidly labelled RNA in EDTA-treated polyribosomes from rat liver
Eur J Biochem, 18 (2), 242-51
DOI 10.1111/j.1432-1033.1971.tb01237.x, PubMed 5541508
Olsnes S (1971)
The isolation of polysomes from rat liver. Contamination by membrane proteins with high affinity to ribosomes
Biochim Biophys Acta, 232 (4), 705-16
PubMed 5556851