Immunogenetic studies of ME/CFS and autoimmune diseases with particular focus on HLA and KIR genes
Single cell profiling of immune cells in thymus to understand the establishment of self-tolerance and development of myasthenia gravis
Single immune cell phenotyping of blood and cerebrospinal fluid in ME/CFS and narcolepsy
Multiomic studies of immune cells with regards to disease activity and treatment response in rheumatoid arthritis and other autoimmune phenotypes
Exploring the phenotype of the immunological cells infiltrating the joint tissue and synovial fluid of the juvenile idiopathic arthritis patients by single cell technologies
Characterizing extracellular vesicles and their protein cargo in immunological diseases
Revealing biomarkers in blood for autoimmune diseases and treatment response
Rydland A, Heinicke F, Nyman TA, Trøseid AS, Flåm ST, Stensland M, Gehin J, Eikeland J, Øvstebø R, Mjaavatten MD, Lie BA(2025) Newly-diagnosed rheumatoid arthritis patients have elevated levels of plasma extracellular vesicles with protein cargo altered towards inflammatory processes Sci Rep, 15(1), 11632 DOI 10.1038/s41598-025-96325-8, PubMed 40185859
Vigeland MD, Flåm ST, Vigeland MD, Zucknick M, Wigemyr M, Bråten LCH, Gjefsen E, Zwart JA, Storheim K, Pedersen LM, Lie BA, The Aim Study Group(2025) Gene Expression Correlates with Disability and Pain Intensity in Patients with Chronic Low Back Pain and Modic Changes in a Sex-Specific Manner Int J Mol Sci, 26(2) DOI 10.3390/ijms26020800, PubMed 39859512
Heimli M, Tennebø Flåm S, Sagsveen Hjorthaug H, Bjørnstad PM, Chernigovskaya M, Le QK, Tekpli X, Greiff V, Lie BA(2023) Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq Sci Rep, 13(1), 17714 DOI 10.1038/s41598-023-44693-4, PubMed 37853083
