❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Immunology ❭ Immunotherapy against solid cancers [Kyte] ❭ Research projects ❭

Research project overview

ALICE: A randomized placebo-controlled phase II study evaluating atezolizumab combined with immunogenic chemotherapy in patients with metastatic triple-negative breast cancer 

REPORT: Reirradiation and PD-1 blockade on recurrent squamous cell head and neck tumors

ICON: A randomized phase IIb study evaluating immunogenic chemotherapy combined with double immunological checkpoint blockade in patients with metastatic luminal B breast cancer 

 
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Recent publications

Rim S, Sakkestad ST, Zhou F, Gullaksen SE, Skavland J, Chauhan SK, Steinsland H, Hanevik K (2023)
Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection
Eur J Immunol, 53 (8), e2250254
DOI 10.1002/eji.202250254, PubMed 37102399

Chauhan SK, Bartolomé Casado R, Landsverk OJB, Johannessen H, Phung D, Nilsen HR, Sætre F, Jahnsen J, Horneland R, Yaqub S, Aandahl EM, Lundin KEA, Bækkevold ES, Jahnsen FL (2023)
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861

Beck C, Casey NP, Persiconi I, Moharrami NN, Sike A, Jin Y, Kyte JA (2023)
Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Biomedicines, 11 (2)
DOI 10.3390/biomedicines11020459, PubMed 36830995

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