Publications 2024

Bresson SE, Ruzzin J (2024)
Persistent organic pollutants disrupt the oxidant/antioxidant balance of INS-1E pancreatic β-cells causing their physiological dysfunctions
Environ Int, 190, 108821
DOI 10.1016/j.envint.2024.108821, PubMed 38885551

Publications 2023

Amini SE, Bresson SE, Ruzzin J (2023)
Mice lacking intestinal Nr1i2 have normal intestinal homeostasis under steady-state conditions and are not hypersensitive to inflammation under lipopolysaccharide treatment
FASEB J, 37 (8), e23117
DOI 10.1096/fj.202301126, PubMed 37490003

Hoefner C, Bryde TH, Pihl C, Tiedemann SN, Bresson SE, Hotiana HA, Khilji MS, Santos TD, Puglia M, Pisano P, Majewska M, Durzynska J, Klindt K, Klusek J, Perone MJ, Bucki R, Hägglund PM, Gourdon PE, Gotfryd K, Urbaniak E, Borowiak M, Wierer M, MacDonald PE, Mandrup-Poulsen T, Marzec MT (2023)
FK506-Binding Protein 2 Participates in Proinsulin Folding
Biomolecules, 13 (1)
DOI 10.3390/biom13010152, PubMed 36671537

Publications 2022

Bresson SE, Isom S, Jensen ET, Huber S, Oulhote Y, Rigdon J, Lovato J, Liese AD, Pihoker C, Dabelea D, Ehrlich S, Ruzzin J (2022)
Associations between persistent organic pollutants and type 1 diabetes in youth
Environ Int, 163, 107175
DOI 10.1016/j.envint.2022.107175, PubMed 35303528

Publications 2020

Argon Y, Bresson SE, Marzec MT, Grimberg A (2020)
Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production
Cells, 9 (8)
DOI 10.3390/cells9081844, PubMed 32781621

Khilji MS, Bresson SE, Verstappen D, Pihl C, Andersen PAK, Agergaard JB, Dahlby T, Bryde TH, Klindt K, Nielsen CK, Walentinsson A, Zivkovic D, Bousquet MP, Tyrberg B, Richardson SJ, Morgan NG, Mandrup-Poulsen T, Marzec MT (2020)
The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient β-cells and is overexpressed in type 2 diabetes pancreatic islets
Am J Physiol Endocrinol Metab, 318 (6), E892-E900
DOI 10.1152/ajpendo.00372.2019, PubMed 32255680

Khilji MS, Verstappen D, Dahlby T, Burstein Prause MC, Pihl C, Bresson SE, Bryde TH, Keller Andersen PA, Klindt K, Zivkovic D, Bousquet-Dubouch MP, Tyrberg B, Mandrup-Poulsen T, Marzec MT (2020)
The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β
PLoS One, 15 (2), e0222432
DOI 10.1371/journal.pone.0222432, PubMed 32053590

Publications 2019

Ghiasi SM, Dahlby T, Hede Andersen C, Haataja L, Petersen S, Omar-Hmeadi M, Yang M, Pihl C, Bresson SE, Khilji MS, Klindt K, Cheta O, Perone MJ, Tyrberg B, Prats C, Barg S, Tengholm A, Arvan P, Mandrup-Poulsen T, Marzec MT (2019)
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling
Diabetes, 68 (4), 747-760
DOI 10.2337/db18-0671, PubMed 30670477