New books on drug target discovery and validation edited by Mouldy Sioud
Mouldy Sioud
Target Discovery and Validation Reviews and Protocols" Volumes 1 and 2 - edited by Mouldy Sioud from the Department of Immunology at the Norwegian Radium Hospital- are recently published by Humana Press - a leading publisher of medical and scientific books.
The books review the most progressive and current methods for drug target discovery and validation. Also, they explore how recent improvement in understanding the molecular mechanisms of human pathology is impacting drug target discovery in the laboratory and in real therapeutics, specifically for cancers and autoimmune disorders.
From major journals, first or last author from the Institute for Cancer Research
Teles-Reis J, Rusten TE(2026) Tumour-host interactions in Drosophila: mechanisms in the tumour micro- and macroenvironment Mol Oncol(in press) DOI 10.1002/1878-0261.70207, PubMed 41546533
Zhang X, Johannessen B, Kidd SG, Bogaard M, Stranger A, Axcrona U, Axcrona K, Skotheim RI(2026) Cell type composition in bulk prostate cancer tissue is a prognostic biomarker Neoplasia, 72, 101272(in press) DOI 10.1016/j.neo.2026.101272, PubMed 41534468
Choudhury SR, Gupta I, Mills I, Mukhina V, Loginov A, Allor E, Anderson A, Cellini A, Robles C, Dyalram D, Lubek J, Wolf J, Taylor R, Hatten K, Vorobyeva N, Gaykalova DA(2026) HOXC6 overexpression stimulates cell migration and correlates with poor prognosis in head and neck squamous cell carcinoma Cell Mol Life Sci(in press) DOI 10.1007/s00018-025-06039-3, PubMed 41521225
Teles-Reis J, Rusten TE(2026) Tumour-host interactions in Drosophila: mechanisms in the tumour micro- and macroenvironment Mol Oncol(in press) DOI 10.1002/1878-0261.70207, PubMed 41546533
Ianevski A, Nader K, Nguyen J, Sorger H, Timonen S, Julia E, Pölöske D, Spirk K, Wagner C, Jungherz D, Nakano M, Kadambat Nair S, Ianevski P, Kankainen M, Dias D, Cichońska A, Pemovska T, Pirker C, Berger W, Braun T, Moriggl R, Bachy E, Mustjoki S, Herling M, Neubauer HAet al.(2026) Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery Cancer Res, 86(2), 295-309 DOI 10.1158/0008-5472.CAN-25-0881, PubMed 41166698
Moura DS, Lopez-Marti J, Tawbi H, Keung E, Wani K, Lazar A, Wang WL, Ingram DR, Meza-Zepeda LA, Myklebost O, Burgess M, Mondaza-Hernandez JL, Hindi N, Martín-Broto J(2026) Validation of a seven-gene predictive SIGNature for the efficacy of Immuno-Oncology PD-1 inhibitors in patients with Sarcoma (SIGNIOS) Clin Cancer Res(in press) DOI 10.1158/1078-0432.CCR-25-2580, PubMed 41537707