New books on drug target discovery and validation edited by Mouldy Sioud
Mouldy Sioud
Target Discovery and Validation Reviews and Protocols" Volumes 1 and 2 - edited by Mouldy Sioud from the Department of Immunology at the Norwegian Radium Hospital- are recently published by Humana Press - a leading publisher of medical and scientific books.
The books review the most progressive and current methods for drug target discovery and validation. Also, they explore how recent improvement in understanding the molecular mechanisms of human pathology is impacting drug target discovery in the laboratory and in real therapeutics, specifically for cancers and autoimmune disorders.
From major journals, first or last author from the Institute for Cancer Research
Rusten TE(2025) Autophagy regulation by signaling Curr Opin Cell Biol, 97, 102595(in press) DOI 10.1016/j.ceb.2025.102595, PubMed 41086756
Høyvik AJK, Stenberg VY, Liukaityte R, Repetto-Llamazares A, Peng Q, Wangen-Riise R, Wiig E, Ma LW, Revheim ME, Juzeniene A(2025) Optimizing [212Pb]Pb-AB001 Radiopharmaceutical Therapy Schedules in PSMA-Positive Subcutaneous Prostate Cancer Xenografts J Nucl Med(in press) DOI 10.2967/jnumed.125.270444, PubMed 41043994
Pharo H, Vedeld HM, Wahlqvist R, Lind GE(2025) Re: Thomas Dreyer, Simone Brandt, Knud Fabrin, et al. Use of the Xpert Bladder Cancer Monitor Urinary Biomarker Test for Guiding Cystoscopy in High-grade Non-muscle-invasive Bladder Cancer: Results from the Randomized Controlled DaBlaCa-15 Trial. Eur Urol 2025;88:23-30 Eur Urol(in press) DOI 10.1016/j.eururo.2025.07.028, PubMed 40998632
Emaldi M, Rey-Iborra E, Alamillo-Maeso P, Pulido R, Nunes-Xavier CE(2026) Analysis of the Functional Impact of Glycosylation on Immune Checkpoint Proteins Methods Mol Biol, 2959, 55-72 DOI 10.1007/978-1-0716-4734-9_4, PubMed 41028258
Rey-Iborra E, Emaldi M, Madariaga M, Pulido R, Nunes-Xavier CE(2026) 3D Spheroids to Study the Impact of Immune Checkpoint Proteins in Solid Tumors Methods Mol Biol, 2959, 141-156 DOI 10.1007/978-1-0716-4734-9_10, PubMed 41028264
Pharo H, Brandt-Winge S, Thorkildsen EM, Vedeld HM, Lind GE(2026) DNA Methylation Analyses of Tissue Samples and Cell-Free DNA by Droplet Digital PCR Methods Mol Biol, 2969, 179-193 DOI 10.1007/978-1-0716-4767-7_12, PubMed 41073866