New books on drug target discovery and validation edited by Mouldy Sioud
Mouldy Sioud
Target Discovery and Validation Reviews and Protocols" Volumes 1 and 2 - edited by Mouldy Sioud from the Department of Immunology at the Norwegian Radium Hospital- are recently published by Humana Press - a leading publisher of medical and scientific books.
The books review the most progressive and current methods for drug target discovery and validation. Also, they explore how recent improvement in understanding the molecular mechanisms of human pathology is impacting drug target discovery in the laboratory and in real therapeutics, specifically for cancers and autoimmune disorders.
From major journals, first or last author from the Institute for Cancer Research
Patel D, Tiusanen V, Karttunen K, Pihlajamaa P, Sahu B(2025) Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes Commun Biol, 8(1), 992 DOI 10.1038/s42003-025-08413-0, PubMed 40610675
Hurley JH, Coyne AN, Miączyńska M, Stenmark H(2025) The expanding repertoire of ESCRT functions in cell biology and disease Nature, 642(8069), 877-888 DOI 10.1038/s41586-025-08950-y, PubMed 40562928
Thulin MH, Ramberg H, Nielsen HK, Grytli HH, Sivanesan S, Pandya AD, Seip K, Andressen KW, Linder A, Øijordsbakken M, Poutanen M, Katz B, Halvorsen B, Mælandsmo GM, Taskén KA(2025) Beta-blockers prolong response to androgen deprivation therapy in prostate cancer through modulation of the neuro-immuno-oncology axis J Transl Med, 23(1), 672 DOI 10.1186/s12967-025-06644-7, PubMed 40528241
Patel D, Tiusanen V, Karttunen K, Pihlajamaa P, Sahu B(2025) Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes Commun Biol, 8(1), 992 DOI 10.1038/s42003-025-08413-0, PubMed 40610675
Stålberg SM, Silwal-Pandit L, Hamfjord J, Nebdal DJH, Lehtiö J, Lingjærde OC, Skålhegg BS, Kure EH(2025) Elevated KRAS protein level is associated with better survival in pancreatic cancer BMC Cancer, 25(1), 1080 DOI 10.1186/s12885-025-14461-w, PubMed 40596921
Pagui ECK, Brant SB, Svendsen K, Frigessi A, Helland Å, Thoresen S, Jonasson C(2025) Comparative Effectiveness of Atezolizumab, Nivolumab and Pembrolizumab in Second-Line Treatment of Advanced Non-Small Cell Lung Cancer Pharmacoepidemiol Drug Saf, 34(7), e70181 DOI 10.1002/pds.70181, PubMed 40552731