Publications 2018

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2017

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2016

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2015

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2014

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2013

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2012

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications 2011

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Annual summary Institute for Cancer Research

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519

Publications

Publications (original articles or review articles) published in 2013 from OUS - Department of Cancer Genetics

42 publications found

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
Signatures of mutational processes in human cancer
Nature, 500 (7463), 415-21
DOI 10.1038/nature12477, PubMed 23945592

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
DOI 10.1371/journal.pone.0072119, PubMed 23977225

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
Genome Biol, 14 (11), R126
DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477

Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
PLoS One, 8 (1), e53014
DOI 10.1371/journal.pone.0053014, PubMed 23382830

Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
Improving breast cancer survival analysis through competition-based multidimensional modeling
PLoS Comput Biol, 9 (5), e1003047
DOI 10.1371/journal.pcbi.1003047, PubMed 23671412

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Nat Genet, 45 (4), 371-84, 384e1-2
DOI 10.1038/ng.2566, PubMed 23535731

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
Cell Stem Cell, 13 (1), 117-30
DOI 10.1016/j.stem.2013.05.004, PubMed 23770079

Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
Int J Radiat Oncol Biol Phys, 86 (4), 791-9
DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419

Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
Triple-negative breast cancer and the need for new therapeutic targets
Am J Pathol, 183 (4), 1064-1074
DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
Am J Hum Genet, 92 (4), 489-503
DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Nat Genet, 45 (4), 392-8, 398e1-2
DOI 10.1038/ng.2561, PubMed 23535733

Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
Cancer Res, 73 (21), 6424-34
DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
PLoS One, 8 (10), e77232
DOI 10.1371/journal.pone.0077232, PubMed 24194875

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
Breast Cancer Res Treat, 141 (3), 397-408
DOI 10.1007/s10549-013-2702-z, PubMed 24091768

Katika MR, Hurtado A (2013)
A functional link between FOXA1 and breast cancer SNPs
Breast Cancer Res, 15 (1), 303
DOI 10.1186/bcr3360, PubMed 23427833

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
BMC Cancer, 13, 456
DOI 10.1186/1471-2407-13-456, PubMed 24093668

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
Mol Oncol, 8 (1), 93-104
DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764

Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
J Med Genet, 50 (10), 666-73
DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393

Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
Clin Cancer Res, 20 (2), 404-12
DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926

Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
Breast Cancer Res Treat, 143 (1), 189-201
DOI 10.1007/s10549-013-2796-3, PubMed 24305980

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
Sci Transl Med, 5 (181), 181re1
DOI 10.1126/scitranslmed.3006112, PubMed 23596205

Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Am J Hum Genet, 93 (6), 1046-60
DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat Genet, 45 (4), 353-61, 361e1-2
DOI 10.1038/ng.2563, PubMed 23535729

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Hum Mol Genet, 23 (7), 1934-46
DOI 10.1093/hmg/ddt581, PubMed 24242184

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
Next-generation sequencing of disseminated tumor cells
Front Oncol, 3, 320
DOI 10.3389/fonc.2013.00320, PubMed 24427740

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
DOI 10.1371/journal.pone.0062153, PubMed 23671585

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
Carcinogenesis, 35 (5), 1012-9
DOI 10.1093/carcin/bgt404, PubMed 24325915

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
Mol Oncol, 8 (2), 273-84
DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
Two Distinct Categories of Focal Deletions in Cancer Genomes
PLoS One, 8 (6), e66264
DOI 10.1371/journal.pone.0066264, PubMed 23805207

Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
ISRN Oncol, 2013, 924971
DOI 10.1155/2013/924971, PubMed 23533813

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
Osteopontin is a prognostic biomarker in non-small cell lung cancer
BMC Cancer, 13, 540
DOI 10.1186/1471-2407-13-540, PubMed 24215488

Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Carcinogenesis, 35 (1), 76-85
DOI 10.1093/carcin/bgt333, PubMed 24104550

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
Personalized cancer care conference
J Pers Med, 3 (2), 70-81
DOI 10.3390/jpm3020070, PubMed 25562519