The ASAC study, Scandinavian multicentre, placebo-controlled, randomized trial, initiated by our group, investigating the role of aspirin as adjuvant after surgery for colorectal liver metastases, is still recruiting patients and has now 300 of 800 patients included (www.asac.no). The trial is funded by Research Council of Norway, Norwegian Cancer Society, and KLINBEFORSK.
EXCALIBUR study; single centre, un-blinded, three-armed randomized trial for patients with high load of colorectal liver metastases, treated with 1)liver transplantation 2)liver resection 3)hepatic artery infusion of chemotherapy. The trial is approved by the Ethical committee and Norwegian Medicinal Agency and will to be initiated in 2021 (www.excaliburstudy.com).
Precision Medicine in Early Diagnostics and Therapy of Biliary Tract Cancer; is a collaborative project between several groups, led by Sheraz Yaqub, started December 2020.
TESLA trial: Liver Transplantation for Non-Resectable Intrahepatic Cholangiocarcinoma: a prospective exploratory trial; this is a collaborative study between several groups at OUH-KIT treating patients with cholangiocarcinoma
CAMINO study: Investigate the value of MRI in assessing CRC liver mets compared to CT scan, and if MRI affects the surgical decision.
Yaqub S, Røsok B, Gladhaug IP, Labori KJ(2024) Pancreatic duct occlusion with polychloroprene-based glue for the management of postoperative pancreatic fistula after pancreatoduodenectomy-an outdated approach? Front Surg, 11, 1386708 DOI 10.3389/fsurg.2024.1386708, PubMed 38645504
Hoogteijling TJ, Abu Hilal M, Zimmitti G, Aghayan DL, Wu AGR, Cipriani F, Gruttadauria S, Scatton O, Long TCD, Herman P, Marino MV, Mazzaferro V, Chiow AKH, Sucandy I, Ivanecz A, Choi SH, Lee JH, Gastaca M, Vivarelli M, Giuliante F, Ruzzenente A, Yong CC, Yin M, Fondevila C, Efanov Met al.(2024) Impact of neoadjuvant chemotherapy on short-term outcomes after simple and complex minimally invasive minor hepatectomy for colorectal liver metastases: A propensity-score matched and coarsened exact matched study Eur J Surg Oncol, 50(6), 108309(in press) DOI 10.1016/j.ejso.2024.108309, PubMed 38626588
Yaqub S, Edwin B, Hammoud Z, Herrera-Almario G, Jabir B, Lassen K, Line PD, Lopez-Gonzalez MA, Puttick M, Saadelnour MAI, Sampaio-Neto J, Sampath R, Sementsov KV, Siriwardena AK, Sparrelid E, Stein AB, Sutcliffe R, Taflin H, Takla H, Valdec S, Vinoya CN, Zaid W, Wigmore SJ(2024) Gaza War: Too many citizens being killed Br J Surg, 111(4) DOI 10.1093/bjs/znae094, PubMed 38606902