Publications 2024

Holm MB, Lenggenhager D, Detlefsen S, Sántha P, Verbeke CS (2024)
Identification of tumour regression in neoadjuvantly treated pancreatic cancer is based on divergent and nonspecific criteria
Histopathology (in press)
DOI 10.1111/his.15190, PubMed 38571446

Labori KJ, Bratlie SO, Andersson B, Angelsen JH, Biörserud C, Björnsson B, Bringeland EA, Elander N, Garresori H, Grønbech JE, Haux J, Hemmingsson O, Liljefors MG, Myklebust TÅ, Nymo LS, Peltola K, Pfeiffer P, Sallinen V, Sandström P, Sparrelid E, Stenvold H, Søreide K, Tingstedt B, Verbeke C, Öhlund D et al. (2024)
Neoadjuvant FOLFIRINOX versus upfront surgery for resectable pancreatic head cancer (NORPACT-1): a multicentre, randomised, phase 2 trial
Lancet Gastroenterol Hepatol, 9 (3), 205-217
DOI 10.1016/S2468-1253(23)00405-3, PubMed 38237621

Leonhardt CS, Hank T, Pils D, Gustorff C, Sahora K, Schindl M, Verbeke CS, Strobel O, Klaiber U (2024)
Prognostic impact of resection margin status on survival after neoadjuvant treatment for pancreatic cancer: systematic review and meta-analysis
Int J Surg, 110 (1), 453-463
DOI 10.1097/JS9.0000000000000792, PubMed 38315795

Uijterwijk BA, Lemmers DH, Fusai GK, Zerbi A, Salvia R, Sparrelid E, White S, Björnsson B, Mavroeidis VK, Roberts KJ, Mazzola M, Cabús SS, Soonawalla Z, Korkolis D, Serradilla M, Pessaux P, Luyer M, Mowbray N, Ielpo B, Mazzotta A, Kleeff J, Boggi U, Muñoz MAS, Goh BKP, Andreotti E et al. (2024)
Differences in Lymph Node Metastases Patterns Among Non-pancreatic Periampullary Cancers and Histologic Subtypes: An International Multicenter Retrospective Cohort Study and Systematic Review
Ann Surg Oncol (in press)
DOI 10.1245/s10434-024-15213-z, PubMed 38602578

Publications 2023

Amrutkar M, Berg K, Balto A, Skilbrei MG, Finstadsveen AV, Aasrum M, Gladhaug IP, Verbeke CS (2023)
Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis
Cancer Cell Int, 23 (1), 9
DOI 10.1186/s12935-023-02852-7, PubMed 36658582

Farnes I, Kleive D, Verbeke CS, Aabakken L, Issa-Epe A, Småstuen MC, Fosby BV, Dueland S, Line PD, Labori KJ (2023)
Resection rates and intention-to-treat outcomes in borderline and locally advanced pancreatic cancer: real-world data from a population-based, prospective cohort study (NORPACT-2)
BJS Open, 7 (6)
DOI 10.1093/bjsopen/zrad137, PubMed 38155512

Farnes I, Paulsen V, Verbeke CS, Tønnesen CJ, Aabakken L, Labori KJ (2023)
Performance and safety of diagnostic EUS FNA/FNB and therapeutic ERCP in patients with borderline resectable and locally advanced pancreatic cancer - results from a population-based, prospective cohort study
Scand J Gastroenterol, 59 (4), 496-502
DOI 10.1080/00365521.2023.2290456, PubMed 38126766

Li Y, Amrutkar M, Finstadsveen AV, Dalen KT, Verbeke CS, Gladhaug IP (2023)
Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells
Cancer Cell Int, 23 (1), 276
DOI 10.1186/s12935-023-03138-8, PubMed 37978383

Publications 2022

Amrutkar M, Verbeke CS, Finstadsveen AV, Dorg L, Labori KJ, Gladhaug IP (2022)
Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
Mol Oncol, 17 (1), 59-81
DOI 10.1002/1878-0261.13344, PubMed 36400567

Fjeld K, Gravdal A, Brekke RS, Alam J, Wilhelm SJ, El Jellas K, Pettersen HN, Lin J, Solheim MH, Steine SJ, Johansson BB, Njølstad PR, Verbeke CS, Xiao X, Lowe ME, Molven A (2022)
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Pancreatology, 22 (8), 1099-1111
DOI 10.1016/j.pan.2022.11.003, PubMed 36379850

Holm MB, Verbeke CS (2022)
Prognostic Impact of Resection Margin Status on Distal Pancreatectomy for Ductal Adenocarcinoma
Curr Oncol, 29 (9), 6551-6563
DOI 10.3390/curroncol29090515, PubMed 36135084

Janssen BV, van Roessel S, van Dieren S, de Boer O, Adsay V, Basturk O, Brosens L, Campbell F, Chatterjee D, Chou A, Doglioni C, Esposito I, Feakins R, Fuchs TL, Fukushima N, Gill AJ, Hong SM, Hruban RH, Kaplan J, Krasinkas A, Luchini C, Shi C, Singhi A, Thompson E, Velthuysen MF et al. (2022)
Histopathological tumour response scoring in resected pancreatic cancer following neoadjuvant therapy: international interobserver study (ISGPP-1)
Br J Surg, 110 (1), 67-75
DOI 10.1093/bjs/znac350, PubMed 36331867

Tran ML, Holm MB, Verbeke CS (2022)
Tumour Size and T-Stage in Pancreatic Cancer Resection Specimens Depend on the Pathology Examination Approach
Cancers (Basel), 14 (10)
DOI 10.3390/cancers14102471, PubMed 35626076

Vujasinovic M, Pozzi Mucelli R, Grigoriadis A, Palmér I, Asplund E, Rutkowski W, Baldaque-Silva F, Waldthaler A, Ghorbani P, Verbeke CS, Löhr JM (2022)
Paraduodenal pancreatitis - problem in the groove
Scand J Gastroenterol, 1-8 (in press)
DOI 10.1080/00365521.2022.2036806, PubMed 35138983

Publications 2021

Nikolic S, Ghorbani P, Pozzi Mucelli R, Ghazi S, Baldaque-Silva F, Del Chiaro M, Sparrelid E, Verbeke CS, Löhr JM, Vujasinovic M (2021)
Surgery in Autoimmune Pancreatitis
Dig Surg, 39 (1), 32-41
DOI 10.1159/000521490, PubMed 34915509

Rasmussen LG, Verbeke CS, Sørensen MD, Pfeiffer P, Tan Q, Mortensen MB, Fristrup C, Detlefsen S (2021)
Gene expression profiling of morphologic subtypes of pancreatic ductal adenocarcinoma using surgical and EUS-FNB specimens
Pancreatology, 21 (3), 530-543
DOI 10.1016/j.pan.2021.01.025, PubMed 33637450

Sahakyan MA, Verbeke CS, Tholfsen T, Ignjatovic D, Kleive D, Buanes T, Lassen K, Rosok BI, Labori KJ, Edwin B (2021)
ASO Visual Abstract: Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma
Ann. Surg. Oncol., 28 (SUPPL 3 3), 570
DOI 10.1245/s10434-021-10531-y

Sahakyan MA, Verbeke CS, Tholfsen T, Ignjatovic D, Kleive D, Buanes T, Lassen K, Røsok BI, Labori KJ, Edwin B (2021)
Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma
Ann Surg Oncol, 29 (1), 366-375
DOI 10.1245/s10434-021-10464-6, PubMed 34296358

Sántha P, Lenggenhager D, Finstadsveen A, Dorg L, Tøndel K, Amrutkar M, Gladhaug IP, Verbeke C (2021)
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040895, PubMed 33672734

Soer EC, Verbeke CS (2021)
Pathology reporting of margin status in locally advanced pancreatic cancer: challenges and uncertainties
J Gastrointest Oncol, 12 (5), 2512-2520
DOI 10.21037/jgo-20-391, PubMed 34790412

van Hilst J, Korrel M, Lof S, de Rooij T, Vissers F, Al-Sarireh B, Alseidi A, Bateman AC, Björnsson B, Boggi U, Bratlie SO, Busch O, Butturini G, Casadei R, Dijk F, Dokmak S, Edwin B, van Eijck C, Esposito A, Fabre JM, Falconi M, Ferrari G, Fuks D, Groot Koerkamp B, Hackert T et al. (2021)
Minimally invasive versus open distal pancreatectomy for pancreatic ductal adenocarcinoma (DIPLOMA): study protocol for a randomized controlled trial
Trials, 22 (1), 608
DOI 10.1186/s13063-021-05506-z, PubMed 34503548

Verbeke C, Webster F, Brosens L, Campbell F, Del Chiaro M, Esposito I, Feakins RM, Fukushima N, Gill AJ, Kakar S, Kench JG, Krasinskas AM, van Laethem JL, Schaeffer DF, Washington K (2021)
Dataset for the reporting of carcinoma of the exocrine pancreas: recommendations from the International Collaboration on Cancer Reporting (ICCR)
Histopathology, 79 (6), 902-912
DOI 10.1111/his.14540, PubMed 34379823

Publications 2020

Amrutkar M, Larsen EK, Aasrum M, Finstadsveen AV, Andresen PA, Verbeke CS, Gladhaug IP (2020)
Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor
Cells, 9 (1)
DOI 10.3390/cells9010227, PubMed 31963309

Amrutkar M, Vethe NT, Verbeke CS, Aasrum M, Finstadsveen AV, Sántha P, Gladhaug IP (2020)
Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123628, PubMed 33287390

Cobo I, Iglesias M, Flández M, Verbeke C, Del Pozo N, Llorente M, Lawlor R, Luchini C, Rusev B, Scarpa A, Real FX (2020)
Epithelial Nr5a2 heterozygosity cooperates with mutant Kras in the development of pancreatic cystic lesions
J Pathol, 253 (2), 174-185
DOI 10.1002/path.5570, PubMed 33079429

Esposito I, Hruban RH, Verbeke C, Terris B, Zamboni G, Scarpa A, Morohoshi T, Suda K, Luchini C, Klimstra DS, Adsay V, Haeberle L, Saluja A, Fernandez-Del Castillo C, Sheel A, Neoptolemos JP, Isaji S, Shimosegawa T, Whitcomb DC, Campbell F, Working group for the International (IAP – APA – JPS – EPC) Consensus Guidelines for Chronic Pancreatitis (2020)
Guidelines on the histopathology of chronic pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with the International Association of Pancreatology, the American Pancreatic Association, the Japan Pancreas Society, and the European Pancreatic Club
Pancreatology, 20 (4), 586-593
DOI 10.1016/j.pan.2020.04.009, PubMed 32414657

Ghaderi M, Fernández Moro C, Pouso Elduayen S, Hultin E, Verbeke CS, Björnstedt M, Dillner J (2020)
Genome-wide transcriptome profiling of ex-vivo precision-cut slices from human pancreatic ductal adenocarcinoma
Sci Rep, 10 (1), 9070
DOI 10.1038/s41598-020-65911-3, PubMed 32493953

Hugenschmidt H, Labori KJ, Brunborg C, Verbeke CS, Seeberg LT, Bendigtsen Schirmer C, Renolen A, Borgen E, Naume B, Wiedswang G (2020)
Cytokeratin-positive cells in the bone marrow from patients with pancreatic, periampullary malignancy and benign pancreatic disease show no prognostic information
BMC Cancer, 20 (1), 1107
DOI 10.1186/s12885-020-07510-z, PubMed 33198661

Hugenschmidt H, Labori KJ, Brunborg C, Verbeke CS, Seeberg LT, Schirmer CB, Renolen A, Borgen EF, Naume B, Wiedswang G (2020)
Circulating Tumor Cells are an Independent Predictor of Shorter Survival in Patients Undergoing Resection for Pancreatic and Periampullary Adenocarcinoma
Ann Surg, 271 (3), 549-558
DOI 10.1097/SLA.0000000000003035, PubMed 30216219

Janssen BV, Tutucu F, van Roessel S, Adsay V, Basturk O, Campbell F, Doglioni C, Esposito I, Feakins R, Fukushima N, Gill AJ, Hruban RH, Kaplan J, Koerkamp BG, Hong SM, Krasinskas A, Luchini C, Offerhaus J, Sarasqueta AF, Shi C, Singhi A, Stoop TF, Soer EC, Thompson E, van Tienhoven G et al. (2020)
Amsterdam International Consensus Meeting: tumor response scoring in the pathology assessment of resected pancreatic cancer after neoadjuvant therapy
Mod Pathol, 34 (1), 4-12
DOI 10.1038/s41379-020-00683-9, PubMed 33041332

Lof S, Rajak R, Vissers FLIM, Korrel M, Bateman A, Verheij J, Verbeke C, Cataldo I, Besselink MG, Abu Hilal M (2020)
DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
J Vis Exp (156)
DOI 10.3791/60343, PubMed 32065168

Löhr JM, Beuers U, Vujasinovic M, Alvaro D, Frøkjær JB, Buttgereit F, Capurso G, Culver EL, de-Madaria E, Della-Torre E, Detlefsen S, Dominguez-Muñoz E, Czubkowski P, Ewald N, Frulloni L, Gubergrits N, Duman DG, Hackert T, Iglesias-Garcia J, Kartalis N, Laghi A, Lammert F, Lindgren F, Okhlobystin A, Oracz G et al. (2020)
European Guideline on IgG4-related digestive disease - UEG and SGF evidence-based recommendations
United European Gastroenterol J, 8 (6), 637-666
DOI 10.1177/2050640620934911, PubMed 32552502

Vujasinovic M, Maier P, Maetzel H, Valente R, Pozzi-Mucelli R, Moro CF, Haas SL, Said K, Verbeke CS, Maisonneuve P, Löhr JM (2020)
Immunoglobulin G subtypes-1 and 2 differentiate immunoglobulin G4-associated sclerosing cholangitis from primary sclerosing cholangitis
United European Gastroenterol J, 8 (5), 584-593
DOI 10.1177/2050640620916027, PubMed 32349627

Wesali S, Demir MA, Verbeke CS, Andersson M, Bratlie SO, Sadik R (2020)
EUS is accurate in characterizing pancreatic cystic lesions; a prospective comparison with cross-sectional imaging in resected cases
Surg Endosc, 35 (12), 6650-6659
DOI 10.1007/s00464-020-08166-3, PubMed 33259018

Publications 2019

Amrutkar M, Aasrum M, Verbeke CS, Gladhaug IP (2019)
Secretion of fibronectin by human pancreatic stellate cells promotes chemoresistance to gemcitabine in pancreatic cancer cells
BMC Cancer, 19 (1), 596
DOI 10.1186/s12885-019-5803-1, PubMed 31208372

Arnelo U, Rangelova E, Del Chiaro M, Valente R, Verbeke C (2019)
RE: correct reporting is of utmost importance when a controversial treatment is being evaluated
HPB (Oxford), 21 (9), 1251-1252
DOI 10.1016/j.hpb.2019.04.009, PubMed 31109873

Del Chiaro M, Arnelo U, Rangelova E, Valente R, Verbeke C (2019)
RE: Pancreatectomy with arterial resection
HPB (Oxford), 21 (9), 1254-1255
DOI 10.1016/j.hpb.2019.06.003, PubMed 31320240

Held T, Verbeke CS, Strobel O, Rutkowski W, Villard C, Moro CF, Del Chiaro M, Büchler M, Heuchel R, Löhr M (2019)
Immunohistochemical profiling of liver metastases and matched-pair analysis in patients with metastatic pancreatic ductal adenocarcinoma
Pancreatology, 19 (7), 963-970
DOI 10.1016/j.pan.2019.09.005, PubMed 31542399

Kleive D, Labori KJ, Line PD, Gladhaug IP, Verbeke CS (2019)
Pancreatoduodenectomy with venous resection for ductal adenocarcinoma rarely achieves complete (R0) resection
HPB (Oxford), 22 (1), 50-57
DOI 10.1016/j.hpb.2019.05.005, PubMed 31186199

Lenggenhager D, Amrutkar M, Sántha P, Aasrum M, Löhr JM, Gladhaug IP, Verbeke CS (2019)
Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions with Pancreatic Cancer Cells
Cells, 8 (1)
DOI 10.3390/cells8010023, PubMed 30621293

Misra S, Moro CF, Del Chiaro M, Pouso S, Sebestyén A, Löhr M, Björnstedt M, Verbeke CS (2019)
Ex vivo organotypic culture system of precision-cut slices of human pancreatic ductal adenocarcinoma
Sci Rep, 9 (1), 2133
DOI 10.1038/s41598-019-38603-w, PubMed 30765891

Vujasinovic M, Pozzi Mucelli RM, Valente R, Verbeke CS, Haas SL, Löhr JM (2019)
Kidney Involvement in Patients with Type 1 Autoimmune Pancreatitis
J Clin Med, 8 (2)
DOI 10.3390/jcm8020258, PubMed 30781677

Ånonsen K, Sahakyan MA, Kleive D, Waage A, Verbeke C, Hauge T, Buanes T, Edwin B, Labori KJ (2019)
Trends in management and outcome of cystic pancreatic lesions - analysis of 322 cases undergoing surgical resection
Scand J Gastroenterol, 54 (8), 1051-1057
DOI 10.1080/00365521.2019.1642379, PubMed 31322457

Publications 2018

Del Chiaro M, Rangelova E, Halimi A, Ateeb Z, Scandavini C, Valente R, Segersvärd R, Arnelo U, Verbeke CS (2018)
Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer
HPB (Oxford), 21 (2), 219-225
DOI 10.1016/j.hpb.2018.07.017, PubMed 30093144

Kamposioras K, Tsimplouli C, Verbeke C, Anthoney A, Daoukopoulou A, Papandreou CN, Sakellaridis N, Vassilopoulos G, Potamianos SP, Liakouli V, Migneco G, Del Galdo F, Dimas K (2018)
Silencing of caveolin-1 in fibroblasts as opposed to epithelial tumor cells results in increased tumor growth rate and chemoresistance in a human pancreatic cancer model
Int J Oncol, 54 (2), 537-549
DOI 10.3892/ijo.2018.4640, PubMed 30483772

Verbeke C, Dobosz M, Buchler M, Hać S (2018)
Pancreatic cancer - summary of the session of 6th International Pancreatic Days in Gdynia 27-30 October 2016
Pol Przegl Chir, 90 (6), 1-6
DOI 10.5604/01.3001.0012.7408, PubMed 30652685

Verbeke C, Häberle L, Lenggenhager D, Esposito I (2018)
Pathology assessment of pancreatic cancer following neoadjuvant treatment: Time to move on
Pancreatology, 18 (5), 467-476
DOI 10.1016/j.pan.2018.04.010, PubMed 29843972

Vujasinovic M, Valente R, Maier P, von Beckerath V, Haas SL, Arnelo U, Del Chiaro M, Kartalis N, Pozzi-Mucelli RM, Fernandez-Moro C, Verbeke CS, Yu J, Ye W, Löhr JM (2018)
Diagnosis, treatment and long-term outcome of autoimmune pancreatitis in Sweden
Pancreatology, 18 (8), 900-904
DOI 10.1016/j.pan.2018.09.003, PubMed 30236651

Publications 2017

Del Chiaro M, Verbeke C (2017)
Intraductal papillary mucinous neoplasms of the pancreas: reporting clinically relevant features
Histopathology, 70 (6), 850-860
DOI 10.1111/his.13131, PubMed 27878841

Fernández Moro C, Fernandez-Woodbridge A, Alistair D'souza M, Zhang Q, Bozoky B, Vasan SK, Catalano P, Heuchel R, Shtembari S, Del Chiaro M, Danielsson O, Björnstedt M, Löhr JM, Isaksson B, Verbeke C, Bozóky B (2017)
Correction: Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification
PLoS One, 12 (1), e0171283
DOI 10.1371/journal.pone.0171283, PubMed 28125728

Gjelberg HK, Hoem D, Verbeke CS, Eide J, Cooper JG, Molven A (2017)
Hypoglycemia and decreased insulin requirement caused by malignant insulinoma in a type 1 diabetic patient: when the hoof beats are from a zebra, not a horse
Clin Case Rep, 5 (6), 761-768
DOI 10.1002/ccr3.927, PubMed 28588806

Jabbar KS, Arike L, Verbeke CS, Sadik R, Hansson GC (2017)
Highly Accurate Identification of Cystic Precursor Lesions of Pancreatic Cancer Through Targeted Mass Spectrometry: A Phase IIc Diagnostic Study
J Clin Oncol, 36 (4), 367-375
DOI 10.1200/JCO.2017.73.7288, PubMed 29166170

Kleive D, Berstad AE, Sahakyan MA, Verbeke CS, Naper C, Haugvik SP, Gladhaug IP, Line PD, Labori KJ (2017)
Portal vein reconstruction using primary anastomosis or venous interposition allograft in pancreatic surgery
J Vasc Surg Venous Lymphat Disord, 6 (1), 66-74
DOI 10.1016/j.jvsv.2017.09.003, PubMed 29128301

Labori KJ, Lassen K, Hoem D, Grønbech JE, Søreide JA, Mortensen K, Smaaland R, Sorbye H, Verbeke C, Dueland S (2017)
Neoadjuvant chemotherapy versus surgery first for resectable pancreatic cancer (Norwegian Pancreatic Cancer Trial - 1 (NorPACT-1)) - study protocol for a national multicentre randomized controlled trial
BMC Surg, 17 (1), 94
DOI 10.1186/s12893-017-0291-1, PubMed 28841916

Malgerud L, Lindberg J, Wirta V, Gustafsson-Liljefors M, Karimi M, Moro CF, Stecker K, Picker A, Huelsewig C, Stein M, Bohnert R, Del Chiaro M, Haas SL, Heuchel RL, Permert J, Maeurer MJ, Brock S, Verbeke CS, Engstrand L, Jackson DB, Grönberg H, Löhr JM (2017)
Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer
Mol Oncol, 11 (10), 1413-1429
DOI 10.1002/1878-0261.12108, PubMed 28675654

Omazic B, Ayoglu B, Löhr M, Segersvärd R, Verbeke C, Magalhaes I, Potacova Z, Mattsson J, Terman A, Ghazi S, Albiin N, Kartalis N, Nilsson P, Poiret T, Zhenjiang L, Heuchel R, Schwenk JM, Permert J, Maeurer MJ, Ringden O (2017)
A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer
J Immunother, 40 (4), 132-139
DOI 10.1097/CJI.0000000000000164, PubMed 28338506

Sahakyan MA, Haugvik SP, Røsok BI, Kazaryan AM, Ignjatovic D, Buanes T, Labori KJ, Verbeke CS, Edwin B (2017)
Can standardized pathology examination increase the lymph node yield following laparoscopic distal pancreatectomy for ductal adenocarcinoma?
HPB (Oxford), 20 (2), 175-181
DOI 10.1016/j.hpb.2017.08.038, PubMed 28943397

Seleznik GM, Reding T, Peter L, Gupta A, Steiner SG, Sonda S, Verbeke CS, Dejardin E, Khatkov I, Segerer S, Heikenwalder M, Graf R (2017)
Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation
Gut, 67 (9), 1663-1673
DOI 10.1136/gutjnl-2016-313458, PubMed 28774888

Strell C, Norberg KJ, Mezheyeuski A, Schnittert J, Kuninty PR, Moro CF, Paulsson J, Schultz NA, Calatayud D, Löhr JM, Frings O, Verbeke CS, Heuchel RL, Prakash J, Johansen JS, Östman A (2017)
Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC
Br J Cancer, 117 (1), 65-77
DOI 10.1038/bjc.2017.140, PubMed 28524160

Publications 2016

Del Chiaro M, Ateeb Z, Hansson MR, Rangelova E, Segersvärd R, Kartalis N, Ansorge C, Löhr MJ, Arnelo U, Verbeke C (2016)
Survival Analysis and Risk for Progression of Intraductal Papillary Mucinous Neoplasia of the Pancreas (IPMN) Under Surveillance: A Single-Institution Experience
Ann Surg Oncol, 24 (4), 1120-1126
DOI 10.1245/s10434-016-5661-x, PubMed 27822633

Fernández Moro C, Fernandez-Woodbridge A, Alistair D'souza M, Zhang Q, Bozoky B, Kandaswamy SV, Catalano P, Heuchel R, Shtembari S, Del Chiaro M, Danielsson O, Björnstedt M, Löhr JM, Isaksson B, Verbeke C, Bozóky B (2016)
Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification
PLoS One, 11 (11), e0166067
DOI 10.1371/journal.pone.0166067, PubMed 27829047

Haugvik SP, Kaemmerer D, Gaujoux S, Labori KJ, Verbeke CS, Gladhaug IP (2016)
Pathology and Surgical Treatment of High-Grade Pancreatic Neuroendocrine Carcinoma: an Evolving Landscape
Curr Oncol Rep, 18 (5), 28
DOI 10.1007/s11912-016-0518-9, PubMed 26984415

Kleive D, Berstad AE, Verbeke CS, Haugvik SP, Gladhaug IP, Line PD, Labori KJ (2016)
Cold-stored cadaveric venous allograft for superior mesenteric/portal vein reconstruction during pancreatic surgery
HPB (Oxford), 18 (7), 615-22
DOI 10.1016/j.hpb.2016.05.010, PubMed 27346143

Li X, Nania S, Fejzibegovic N, Moro CF, Klopp-Schulze L, Verbeke C, Löhr JM, Heuchel RL (2016)
Cerulein-induced pancreatic fibrosis is modulated by Smad7, the major negative regulator of transforming growth factor-β signaling
Biochim Biophys Acta, 1862 (9), 1839-46
DOI 10.1016/j.bbadis.2016.06.017, PubMed 27349482

Löhr JM, Karimi M, Omazic B, Kartalis N, Verbeke CS, Berkenstam A, Frödin JE (2016)
A phase I dose escalation trial of AXP107-11, a novel multi-component crystalline form of genistein, in combination with gemcitabine in chemotherapy-naive patients with unresectable pancreatic cancer
Pancreatology, 16 (4), 640-5
DOI 10.1016/j.pan.2016.05.002, PubMed 27234064

Meng Q, Liu Z, Rangelova E, Poiret T, Ambati A, Rane L, Xie S, Verbeke C, Dodoo E, Del Chiaro M, Löhr M, Segersvärd R, Maeurer MJ (2016)
Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer
J Immunother, 39 (2), 81-9
DOI 10.1097/CJI.0000000000000111, PubMed 26849077

Pozzi-Mucelli RM, Rinta-Kiikka I, Wünsche K, Laukkarinen J, Labori KJ, Ånonsen K, Verbeke C, Del Chiaro M, Kartalis N (2016)
Pancreatic MRI for the surveillance of cystic neoplasms: comparison of a short with a comprehensive imaging protocol
Eur Radiol, 27 (1), 41-50
DOI 10.1007/s00330-016-4377-4, PubMed 27246720

Tjomsland V, Pomianowska E, Aasrum M, Sandnes D, Verbeke CS, Gladhaug IP (2016)
Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells
Neoplasia, 18 (7), 447-56
DOI 10.1016/j.neo.2016.06.003, PubMed 27435927

Verbeke C (2016)
Morphological heterogeneity in ductal adenocarcinoma of the pancreas - Does it matter?
Pancreatology, 16 (3), 295-301
DOI 10.1016/j.pan.2016.02.004, PubMed 26924665

Verbeke CS, Gladhaug IP (2016)
Dissection of Pancreatic Resection Specimens
Surg Pathol Clin, 9 (4), 523-538
DOI 10.1016/j.path.2016.05.001, PubMed 27926357

Publications 2015

Del Chiaro M, Segersvärd R, Rangelova E, Coppola A, Scandavini CM, Ansorge C, Verbeke C, Blomberg J (2015)
Cattell-Braasch Maneuver Combined with Artery-First Approach for Superior Mesenteric-Portal Vein Resection During Pancreatectomy
J Gastrointest Surg, 19 (12), 2264-8
DOI 10.1007/s11605-015-2958-1, PubMed 26423804

Del Chiaro M, Verbeke C (2015)
Cystic tumors of the pancreas: Opportunities and risks
World J Gastrointest Pathophysiol, 6 (2), 29-32
DOI 10.4291/wjgp.v6.i2.29, PubMed 25977835

Del Chiaro M, Verbeke CS, Kartalis N, Pozzi Mucelli R, Gustafsson P, Hansson J, Haas SL, Segersvärd R, Andren-Sandberg Å, Löhr JM (2015)
Short-term Results of a Magnetic Resonance Imaging-Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer
JAMA Surg, 150 (6), 512-8
DOI 10.1001/jamasurg.2014.3852, PubMed 25853369

Haraldsson E, Swahn F, Verbeke C, Mattsson JS, Enochsson L, Ung KA, Lundell L, Heuchel R, Löhr JM, Arnelo U (2015)
Endoscopic papillectomy and KRAS expression in the treatment of adenoma in the major duodenal papilla
Scand J Gastroenterol, 50 (11), 1419-27
DOI 10.3109/00365521.2015.1046912, PubMed 25971870

Huang J, Löhr JM, Nilsson M, Segersvärd R, Matsson H, Verbeke C, Heuchel R, Kere J, Iafrate AJ, Zheng Z, Ye W (2015)
Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma
Clin Chem, 61 (11), 1408-16
DOI 10.1373/clinchem.2015.238543, PubMed 26378065

Labori KJ, Verbeke CS, Gladhaug IP (2015)
Information needs among patients and a surveillance strategy after surgery for pancreatic and periampullary cancer
HPB (Oxford), 17 (7), 659
DOI 10.1111/hpb.12411, PubMed 25776256

Löhr JM, Lönnebro R, Stigliano S, Haas SL, Swahn F, Enochsson L, Noel R, Segersvärd R, Del Chiaro M, Verbeke CS, Arnelo U (2015)
Outcome of probe-based confocal laser endomicroscopy (pCLE) during endoscopic retrograde cholangiopancreatography: A single-center prospective study in 45 patients
United European Gastroenterol J, 3 (6), 551-60
DOI 10.1177/2050640615579806, PubMed 26668748

Publications 2014

Arnelo U, Siiki A, Swahn F, Segersvärd R, Enochsson L, del Chiaro M, Lundell L, Verbeke CS, Löhr JM (2014)
Single-operator pancreatoscopy is helpful in the evaluation of suspected intraductal papillary mucinous neoplasms (IPMN)
Pancreatology, 14 (6), 510-4
DOI 10.1016/j.pan.2014.08.007, PubMed 25287157

Del Chiaro M, Blomberg J, Segersvärd R, Rangelova E, Ansorge C, Verbeke C (2014)
The use of LigaSure™ Does not Affect Histologic Margin Assessment in Pancreatoduodenectomy (PD) specimens
JOP, 15 (6), 597-9
DOI 10.6092/1590-8577/2856, PubMed 25435577

Del Chiaro M, Mucelli RP, Blomberg J, Segersvärd R, Verbeke C (2014)
Is intraductal tubulopapillary neoplasia a new entity in the spectrum of familial pancreatic cancer syndrome?
Fam Cancer, 13 (2), 227-9
DOI 10.1007/s10689-013-9696-x, PubMed 24317685

Del Chiaro M, Segersvärd R, Lohr M, Verbeke C (2014)
Early detection and prevention of pancreatic cancer: is it really possible today?
World J Gastroenterol, 20 (34), 12118-31
DOI 10.3748/wjg.v20.i34.12118, PubMed 25232247

Del Chiaro M, Segersvärd R, Pozzi Mucelli R, Rangelova E, Kartalis N, Ansorge C, Arnelo U, Blomberg J, Löhr M, Verbeke C (2014)
Comparison of preoperative conference-based diagnosis with histology of cystic tumors of the pancreas
Ann Surg Oncol, 21 (5), 1539-44
DOI 10.1245/s10434-013-3465-9, PubMed 24385209

Gerling M, Zhao Y, Nania S, Norberg KJ, Verbeke CS, Englert B, Kuiper RV, Bergström A, Hassan M, Neesse A, Löhr JM, Heuchel RL (2014)
Real-time assessment of tissue hypoxia in vivo with combined photoacoustics and high-frequency ultrasound
Theranostics, 4 (6), 604-13
DOI 10.7150/thno.7996, PubMed 24723982

Hakeem AR, Verbeke CS, Cairns A, Aldouri A, Smith AM, Menon KV (2014)
A matched-pair analysis of laparoscopic versus open pancreaticoduodenectomy: oncological outcomes using Leeds Pathology Protocol
Hepatobiliary Pancreat Dis Int, 13 (4), 435-41
DOI 10.1016/s1499-3872(14)60048-5, PubMed 25100130

Jabbar KS, Verbeke C, Hyltander AG, Sjövall H, Hansson GC, Sadik R (2014)
Proteomic mucin profiling for the identification of cystic precursors of pancreatic cancer
J Natl Cancer Inst, 106 (2), djt439
DOI 10.1093/jnci/djt439, PubMed 24523528

Jabbar KS, Verbeke C, Hyltander AG, Sjövall H, Hansson GC, Sadik R (2014)
Response
J Natl Cancer Inst, 106 (11)
DOI 10.1093/jnci/dju330, PubMed 25359854

Verbeke CS (2014)
Resection margins in pancreatic cancer: are we entering a new era?
HPB (Oxford), 16 (1), 1-2
DOI 10.1111/hpb.12122, PubMed 24329942

Publications 2013

Al-Sarireh B, Haidermota M, Verbeke C, Rees DA, Yu R, Griffiths AP (2013)
Glucagon cell adenomatosis without glucagon receptor mutation
Pancreas, 42 (2), 360-2
DOI 10.1097/MPA.0b013e31825b6acd, PubMed 23407487

Del Chiaro M, Verbeke C, Salvia R, Klöppel G, Werner J, McKay C, Friess H, Manfredi R, Van Cutsem E, Löhr M, Segersvärd R, European Study Group on Cystic Tumours of the Pancreas (2013)
European experts consensus statement on cystic tumours of the pancreas
Dig Liver Dis, 45 (9), 703-11
DOI 10.1016/j.dld.2013.01.010, PubMed 23415799

Feakins R, Campbell F, Verbeke CS (2013)
Survey of UK histopathologists' approach to the reporting of resection specimens for carcinomas of the pancreatic head
J Clin Pathol, 66 (8), 715-7
DOI 10.1136/jclinpath-2012-201198, PubMed 23580659

Longati P, Jia X, Eimer J, Wagman A, Witt MR, Rehnmark S, Verbeke C, Toftgård R, Löhr M, Heuchel RL (2013)
3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing
BMC Cancer, 13, 95
DOI 10.1186/1471-2407-13-95, PubMed 23446043

Verbeke CS (2013)
Resection margins in pancreatic cancer
Surg Clin North Am, 93 (3), 647-62
DOI 10.1016/j.suc.2013.02.008, PubMed 23632150

Publications 2012

Charlesworth M, Verbeke CS, Falk GA, Walsh M, Smith AM, Morris-Stiff G (2012)
Pancreatic lesions in von Hippel-Lindau disease? A systematic review and meta-synthesis of the literature
J Gastrointest Surg, 16 (7), 1422-8
DOI 10.1007/s11605-012-1847-0, PubMed 22370733

Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW, European Study Group for Pancreatic Cancer (2012)
Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial
JAMA, 308 (2), 147-56
DOI 10.1001/jama.2012.7352, PubMed 22782416

Publications 2011

Verbeke CS, Knapp J, Gladhaug IP (2011)
Tumour growth is more dispersed in pancreatic head cancers than in rectal cancer: implications for resection margin assessment
Histopathology, 59 (6), 1111-21
DOI 10.1111/j.1365-2559.2011.04056.x, PubMed 22175891

Publications 2010

Diosdado B, Buffart TE, Watkins R, Carvalho B, Ylstra B, Tijssen M, Bolijn AS, Lewis F, Maude K, Verbeke C, Nagtegaal ID, Grabsch H, Mulder CJ, Quirke P, Howdle P, Meijer GA (2010)
High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas
Clin Cancer Res, 16 (5), 1391-401
DOI 10.1158/1078-0432.CCR-09-1773, PubMed 20179237

Morris-Stiff GJ, Senda Y, Verbeke CS, Lodge PA (2010)
Papillary adenoma arising in the left hepatic duct: an unusual tumour in an uncommon location
Eur J Gastroenterol Hepatol, 22 (7), 886-8
DOI 10.1097/meg.0b013e3283392a62, PubMed 20545030

Verbeke CS (2010)
Endocrine tumours of the pancreas
Histopathology, 56 (6), 669-82
DOI 10.1111/j.1365-2559.2010.03490.x, PubMed 20546332

Verbeke CS (2010)
Intraductal papillary-mucinous neoplasia of the pancreas: Histopathology and molecular biology
World J Gastrointest Surg, 2 (10), 306-13
DOI 10.4240/wjgs.v2.i10.306, PubMed 21160835

Verbeke CS, Smith AM (2010)
Survival after pancreaticoduodenectomy is not improved by extending resections to achieve negative margins
Ann Surg, 251 (4), 776-7; author reply 777-8
DOI 10.1097/SLA.0b013e3181d57af6, PubMed 20224357

Publications 2009

Abu Hilal M, Malik HZ, Hamilton-Burke W, Verbeke C, Menon KV (2009)
Modified Cattell's pancreaticojejunostomy, buttressing for soft pancreases and an isolated biliopancreatic loop are safety measurements that improve outcome after pancreaticoduodenectomy: a pilot study
HPB (Oxford), 11 (2), 154-60
DOI 10.1111/j.1477-2574.2009.00028.x, PubMed 19590641

Littleford SE, Baird A, Rotimi O, Verbeke CS, Scott N (2009)
Interobserver variation in the reporting of local peritoneal involvement and extramural venous invasion in colonic cancer
Histopathology, 55 (4), 407-13
DOI 10.1111/j.1365-2559.2009.03397.x, PubMed 19817891

Menon KV, Gomez D, Smith AM, Anthoney A, Verbeke CS (2009)
Impact of margin status on survival following pancreatoduodenectomy for cancer: the Leeds Pathology Protocol (LEEPP)
HPB (Oxford), 11 (1), 18-24
DOI 10.1111/j.1477-2574.2008.00013.x, PubMed 19590619

Strickland LA, Ross J, Williams S, Ross S, Romero M, Spencer S, Erickson R, Sutcliffe J, Verbeke C, Polakis P, van Bruggen N, Koeppen H (2009)
Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma
J Pathol, 218 (3), 380-90
DOI 10.1002/path.2545, PubMed 19334050

Verbeke CS, Menon KV (2009)
Redefining resection margin status in pancreatic cancer
HPB (Oxford), 11 (4), 282-9
DOI 10.1111/j.1477-2574.2009.00055.x, PubMed 19718354

Publications 2008

Aparajita R, Gomez D, Verbeke CS, Menon KV (2008)
Papillary adenoma of the distal common bile duct associated with a synchronous carcinoma of the peri-ampullary duodenum
JOP, 9 (2), 212-5
PubMed 18326932

Bonney GK, Gomez D, Rahman SH, Verbeke CS, Prasad KR, Toogood GJ, Lodge JP, Menon KV (2008)
Results following surgical resection for malignant pancreatic neuroendocrine tumours. A single institutional experience
JOP, 9 (1), 19-25
PubMed 18182738

Ching SS, Verbeke CS, Homer-Vanniasinkam S, McMahon MJ (2008)
Comparison of torsional and linear mode ultrasonic coagulating shears for sealing veins
J Laparoendosc Adv Surg Tech A, 18 (6), 819-24
DOI 10.1089/lap.2008.0066, PubMed 19105669

Verbeke CS, Menon KV (2008)
Variability in reporting resection margin status in pancreatic cancer
Ann Surg, 247 (4), 716-7
DOI 10.1097/SLA.0b013e31816a7077, PubMed 18362643

Publications 2007

Foo FJ, Gill U, Verbeke CS, Guthrie JA, Menon KV (2007)
Ampullary carcinoma associated with an annular pancreas
JOP, 8 (1), 50-4
PubMed 17228134

Foo FJ, Verbeke CS, Guthrie JA, Ala A, Menon KV (2007)
Pancreatic and peripancreatic tuberculosis mimicking malignancy
JOP, 8 (2), 201-5
PubMed 17356244

Frank O, Verbeke C, Schwarz N, Mayer J, Fabarius A, Hehlmann R, Leib-Mösch C, Seifarth W (2007)
Variable transcriptional activity of endogenous retroviruses in human breast cancer
J Virol, 82 (4), 1808-18
DOI 10.1128/JVI.02115-07, PubMed 18077721

Menon KV, Hayden JD, Prasad KR, Verbeke CS (2007)
Total laparoscopic pancreaticoduodenectomy and reconstruction for a cholangiocarcinoma of the bile duct
J Laparoendosc Adv Surg Tech A, 17 (6), 775-80
DOI 10.1089/lap.2006.0236, PubMed 18158808

Rahman SH, Verbeke CS, Gomez D, McMahon MJ, Menon KV (2007)
Pancreatico-duodenectomy for complicated groove pancreatitis
HPB (Oxford), 9 (3), 229-34
DOI 10.1080/13651820701216430, PubMed 18333228

Tolan DJ, Harris KM, Sheridan MB, Guthrie JA, England RE, Aldersley M, Verbeke CS, Smith AM (2007)
Periampullary diverticulum: an unusual cause of double duct obstruction
Gastrointest Endosc, 67 (3), 565-7
DOI 10.1016/j.gie.2007.06.016, PubMed 17981279

Publications 2006

Adamthwaite JA, Verbeke CS, Stringer MD, Guillou PJ, Menon KV (2006)
Solid pseudopapillary tumour of the pancreas: diverse presentation, outcome and histology
JOP, 7 (6), 635-42
PubMed 17095844

Gomez D, Rahman SH, Won LF, Verbeke CS, McMahon MJ, Menon KV (2006)
Characterization of malignant pancreatic cystic lesions in the background of chronic pancreatitis
JOP, 7 (5), 465-72
PubMed 16998243

Upadhyay N, Gomez D, Button MF, Verbeke CS, Menon KV (2006)
Retroperitoneal enteric duplication cyst presenting as a pancreatic cystic lesion. A case report
JOP, 7 (5), 492-5
PubMed 16998248

Publications 2005

Dennis JL, Hvidsten TR, Wit EC, Komorowski J, Bell AK, Downie I, Mooney J, Verbeke C, Bellamy C, Keith WN, Oien KA (2005)
Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm
Clin Cancer Res, 11 (10), 3766-72
DOI 10.1158/1078-0432.CCR-04-2236, PubMed 15897574

Sarela AI, Scott N, Verbeke CS, Wyatt JI, Dexter SP, Sue-Ling HM, Guillou PJ (2005)
Diagnostic variation and outcome for high-grade gastric epithelial dysplasia
Arch Surg, 140 (7), 644-9
DOI 10.1001/archsurg.140.7.644, PubMed 16027328

Publications 2004

Sarela AI, Hick DG, Verbeke CS, Casey JF, Guillou PJ, Clark GW (2004)
Persistent acid and bile reflux in asymptomatic patients with Barrett esophagus receiving proton pump inhibitor therapy
Arch Surg, 139 (5), 547-51
DOI 10.1001/archsurg.139.5.547, PubMed 15136356

Publications 2003

Beardsmore DM, Verbeke CS, Davies CL, Guillou PJ, Clark GW (2003)
Apoptotic and proliferative indexes in esophageal cancer: predictors of response to neoadjuvant therapy [corrected]
J Gastrointest Surg, 7 (1), 77-86; discussion 86-7
PubMed 12559188

Beardsmore DM, Verbeke CS, Davies CL, Guillou PJ, Clark GWB (2003)
Apoptotic and proliferative indexes in esophageal cancer: Predictors of response to neoadjuvant therapy apoptosis and proliferation in esophageal cancer
J Gastrointest Surg, 7 (1), 77-87
DOI 10.1016/S1091-255X(02)00141-5, PubMed 29340962

Beardsmore DM, Verbeke CS, Davies CL, Guillou PJ, Clark GWB (2003)
Erratum to: Apoptotic and proliferative indexes in esophageal cancer: Predictors of response to neoadjuvant therapy apoptosis and proliferation in esophageal cancer
J Gastrointest Surg, 7 (4), 583
DOI 10.1016/S1091-255X(03)00068-4, PubMed 29340976

Soares MV, Plunkett FJ, Verbeke CS, Cook JE, Faint JM, Belaramani LL, Fletcher JM, Hammerschmitt N, Rustin M, Bergler W, Beverley PC, Salmon M, Akbar AN (2003)
Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection
Blood, 103 (1), 162-7
DOI 10.1182/blood-2003-06-1791, PubMed 12969961

Publications 2002

Sonwalkar SA, Denyer ME, Verbeke CS, Guillou PJ (2002)
Cancer of appendix as a presenting feature of Crohn's disease
Eur J Gastroenterol Hepatol, 14 (9), 1029-32
DOI 10.1097/00042737-200209000-00017, PubMed 12352226