Publications

Publications published since 2000 from OUS - Department of Cancer Genetics

790 publications found

Publications 2019

  1. Bergholtz H, Lien TG, Ursin G, Holmen MM, Helland Å, Sørlie T, Haakensen VD (2019)
    A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
    J Mammary Gland Biol Neoplasia (in press)
    DOI 10.1007/s10911-018-09423-x, PubMed 30613869
  2. Kraby MR, Opdahl S, Russnes HG, Bofin AM (2019)
    Microvessel density in breast cancer: the impact of field area on prognostic informativeness
    J Clin Pathol (in press)
    DOI 10.1136/jclinpath-2018-205536, PubMed 30630872
  3. Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D, Zou X, Martincorena I, Alexandrov LB, Martin S, Wedge DC, Van Loo P, Ju YS, Smid M, Brinkman AB, Morganella S, Aure MR, Lingjærde OC, Langerød A, Ringnér M, Ahn SM, Boyault S, Brock JE, Broeks A, Butler A, Desmedt C et al. (2019)
    Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences
    Nature (in press)
    DOI 10.1038/s41586-019-0883-2, PubMed 30659290
  4. Zhang R, Lai L, He J, Chen C, You D, Duan W, Dong X, Zhu Y, Lin L, Shen S, Guo Y, Su L, Shafer A, Moran S, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC (2019)
    EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC
    Epigenetics (in press)
    DOI 10.1080/15592294.2019.1573066, PubMed 30665327

Publications 2018

  1. Abravan A, Eide HA, Løndalen AM, Helland Å, Malinen E (2018)
    Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer
    Mol Imaging Biol (in press)
    DOI 10.1007/s11307-018-1226-7, PubMed 29916117
  2. Berg J, Halvorsen AR, Bengtson MB, Taskén KA, Mælandsmo GM, Yndestad A, Halvorsen B, Brustugun OT, Aukrust P, Ueland T, Helland Å (2018)
    Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
    BMC Cancer, 18 (1), 739
    DOI 10.1186/s12885-018-4659-0, PubMed 30005623
  3. Chèneby J, Gheorghe M, Artufel M, Mathelier A, Ballester B (2018)
    ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments
    Nucleic Acids Res, 46 (D1), D267-D275
    DOI 10.1093/nar/gkx1092, PubMed 29126285
  4. Cheng J, Demeulemeester J, Wedge DC, Vollan HKM, Pitt JJ, Russnes HG, Pandey BP, Nilsen G, Nord S, Bignell GR, White KP, Børresen-Dale AL, Campbell PJ, Kristensen VN, Stratton MR, Lingjærde OC, Moreau Y, Van Loo P (2018)
    Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
    Nat Commun, 9 (1), 5397
    DOI 10.1038/s41467-018-07842-2, PubMed 30559362
  5. Eide HA, Knudtsen IS, Sandhu V, Løndalen AM, Halvorsen AR, Abravan A, Kure EH, Bogsrud TV, Brustugun OT, Kyte JA, Malinen E, Helland Å (2018)
    Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy
    Adv Radiat Oncol, 3 (2), 130-138
    DOI 10.1016/j.adro.2017.12.007, PubMed 29904737
  6. Fornes O, Gheorghe M, Richmond PA, Arenillas DJ, Wasserman WW, Mathelier A (2018)
    MANTA2, update of the Mongo database for the analysis of transcription factor binding site alterations
    Sci Data, 5, 180141
    DOI 10.1038/sdata.2018.141, PubMed 30040077
  7. Gandara DR, von Pawel J, Mazieres J, Sullivan R, Helland Å, Han JY, Ponce Aix S, Rittmeyer A, Barlesi F, Kubo T, Park K, Goldschmidt J, Gandhi M, Yun C, Yu W, Matheny C, He P, Sandler A, Ballinger M, Fehrenbacher L (2018)
    Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study
    J Thorac Oncol, 13 (12), 1906-1918
    DOI 10.1016/j.jtho.2018.08.2027, PubMed 30217492
  8. Gheorghe M, Sandve GK, Khan A, Chèneby J, Ballester B, Mathelier A (2018)
    A map of direct TF-DNA interactions in the human genome
    Nucleic Acids Res (in press)
    DOI 10.1093/nar/gky1210, PubMed 30517703
  9. Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE et al. (2018)
    Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
    Nat Commun, 9, 16193
    DOI 10.1038/ncomms16193, PubMed 29633761
  10. Glodzik D, Purdie C, Rye IH, Simpson PT, Staaf J, Span PN, Russnes HG, Nik-Zainal S (2018)
    Mutational mechanisms of amplifications revealed by analysis of clustered rearrangements in breast cancers
    Ann Oncol, 29 (11), 2223-2231
    DOI 10.1093/annonc/mdy404, PubMed 30252041
  11. Guo Y, Zhang R, Shen S, Wei Y, Salama SM, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Su L, Zhu Z, Staaf J, Helland Å, Esteller M, Christiani DC (2018)
    DNA Methylation of LRRC3B: A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients
    Cancer Epidemiol Biomarkers Prev, 27 (12), 1527-1535
    DOI 10.1158/1055-9965.EPI-18-0454, PubMed 30185536
  12. Halvorsen AR, Sandhu V, Sprauten M, Flote VG, Kure EH, Brustugun OT, Helland Å (2018)
    Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab
    Acta Oncol, 57 (9), 1225-1231
    DOI 10.1080/0284186X.2018.1465585, PubMed 29683761
  13. Helland A (2018)
    Groundbreaking basic research
    Tidsskr. Nor. Laegeforen., 138 (20), 1905
  14. Höglander EK, Nord S, Wedge DC, Lingjærde OC, Silwal-Pandit L, Gythfeldt HV, Vollan HKM, Fleischer T, Krohn M, Schlitchting E, Borgen E, Garred Ø, Holmen MM, Wist E, Naume B, Van Loo P, Børresen-Dale AL, Engebraaten O, Kristensen V (2018)
    Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
    Genome Med, 10 (1), 92
    DOI 10.1186/s13073-018-0601-y, PubMed 30497530
  15. Jabeen S, Zucknick M, Nome M, Dannenfelser R, Fleischer T, Kumar S, Lüders T, von der Lippe Gythfeldt H, Troyanskaya O, Kyte JA, Børresen-Dale AL, Naume B, Tekpli X, Engebraaten O, Kristensen V (2018)
    Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab
    Oncoimmunology, 7 (11), e1457598
    DOI 10.1080/2162402X.2018.1457598, PubMed 30377556
  16. Kaveh F, Baumbusch LO, Nebdal D, Børresen-Dale AL, Lingjærde OC, Edvardsen H, Kristensen VN, Solvang HK (2018)
    Correction to: A systematic comparison of copy number alterations in four types of female cancer
    BMC Cancer, 18 (1), 80
    DOI 10.1186/s12885-017-3766-7, PubMed 29338700
  17. Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2018)
    JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
    Nucleic Acids Res, 46 (D1), D1284
    DOI 10.1093/nar/gkx1188, PubMed 29161433
  18. Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2018)
    JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
    Nucleic Acids Res, 46 (D1), D260-D266
    DOI 10.1093/nar/gkx1126, PubMed 29140473
  19. Khan A, Mathelier A (2018)
    JASPAR RESTful API: accessing JASPAR data from any programming language
    Bioinformatics, 34 (9), 1612-1614
    DOI 10.1093/bioinformatics/btx804, PubMed 29253085
  20. Khan A, Mathelier A, Zhang X (2018)
    Super-enhancers are transcriptionally more active and cell type-specific than stretch enhancers
    Epigenetics, 13 (9), 910-922
    DOI 10.1080/15592294.2018.1514231, PubMed 30169995
  21. Khan A, Montenegro-Montero A, Mathelier A (2018)
    Put science first and formatting later
    EMBO Rep, 19 (5)
    DOI 10.15252/embr.201845731, PubMed 29650529
  22. Lecellier CH, Wasserman WW, Mathelier A (2018)
    Human Enhancers Harboring Specific Sequence Composition, Activity, and Genome Organization Are Linked to the Immune Response
    Genetics, 209 (4), 1055-1071
    DOI 10.1534/genetics.118.301116, PubMed 29871881
  23. Lindholm E, Leivonen SK, Undlien E, Nebdal D, Git A, Caldas C, Børresen-Dale AL, Sahlberg KK (2018)
    miR-342-5p as a potential regulator of HER2 breast cancer cell growth
    Microrna (in press)
    DOI 10.2174/2211536608666181206124922, PubMed 30520388
  24. Mauger F, Kernaleguen M, Lallemand C, Kristensen VN, Deleuze JF, Tost J (2018)
    Enrichment of methylated molecules using enhanced-ice-co-amplification at lower denaturation temperature-PCR (E-ice-COLD-PCR) for the sensitive detection of disease-related hypermethylation
    Epigenomics, 10 (5), 525-537
    DOI 10.2217/epi-2017-0166, PubMed 29697281
  25. Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L, Lee A, Tyrer JP, Chen TH, Wang Q, Bolla MK, Yang X, Adank MA, Ahearn T, Aittomäki K, Allen J, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Auer PL, Auvinen P, Barrdahl M, Beane Freeman LE, Beckmann MW et al. (2018)
    Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
    Am J Hum Genet, 104 (1), 21-34
    DOI 10.1016/j.ajhg.2018.11.002, PubMed 30554720
  26. Nguyen CB, Kumar S, Zucknick M, Kristensen VN, Gjerstad J, Nilsen H, Wyller VB (2018)
    Associations between clinical symptoms, plasma norepinephrine and deregulated immune gene networks in subgroups of adolescent with Chronic Fatigue Syndrome
    Brain Behav Immun (in press)
    DOI 10.1016/j.bbi.2018.11.008, PubMed 30419269
  27. Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
    The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
    Biol Res, 51 (1), 3
    DOI 10.1186/s40659-017-0151-6, PubMed 29316982
  28. Novello S, Mazières J, Oh IJ, de Castro J, Migliorino MR, Helland Å, Dziadziuszko R, Griesinger F, Kotb A, Zeaiter A, Cardona A, Balas B, Johannsdottir HK, Das-Gupta A, Wolf J (2018)
    Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study
    Ann Oncol, 29 (6), 1409-1416
    DOI 10.1093/annonc/mdy121, PubMed 29668860
  29. O'Mara TA, Glubb DM, Amant F, Annibali D, Ashton K, Attia J, Auer PL, Beckmann MW, Black A, Bolla MK, Brauch H, Brenner H, Brinton L, Buchanan DD, Burwinkel B, Chang-Claude J, Chanock SJ, Chen C, Chen MM, Cheng THT, Clarke CL, Clendenning M, Cook LS, Couch FJ, Cox A et al. (2018)
    Identification of nine new susceptibility loci for endometrial cancer
    Nat Commun, 9 (1), 3166
    DOI 10.1038/s41467-018-05427-7, PubMed 30093612
  30. Painter JN, O'Mara TA, Morris AP, Cheng THT, Gorman M, Martin L, Hodson S, Jones A, Martin NG, Gordon S, Henders AK, Attia J, McEvoy M, Holliday EG, Scott RJ, Webb PM, Fasching PA, Beckmann MW, Ekici AB, Hein A, Rübner M, Hall P, Czene K, Dörk T, Dürst M et al. (2018)
    Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses
    Cancer Med, 7 (5), 1978-1987
    DOI 10.1002/cam4.1445, PubMed 29608257
  31. Prasmickaite L, Tenstad EM, Pettersen S, Jabeen S, Egeland EV, Nord S, Pandya A, Haugen MH, Kristensen VN, Børresen-Dale AL, Oslo Breast Cancer Research Consortium (OSBREAC), Engebråten O, Maelandsmo GM (2018)
    Basal-like breast cancer engages tumor-supportive macrophages via secreted factors induced by extracellular S100A4
    Mol Oncol, 12 (9), 1540-1558
    DOI 10.1002/1878-0261.12319, PubMed 29741811
  32. Risberg B, Tsui DWY, Biggs H, Ruiz-Valdepenas Martin de Almagro A, Dawson SJ, Hodgkin C, Jones L, Parkinson C, Piskorz A, Marass F, Chandrananda D, Moore E, Morris J, Plagnol V, Rosenfeld N, Caldas C, Brenton JD, Gale D (2018)
    Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients
    J Mol Diagn, 20 (6), 883-892
    DOI 10.1016/j.jmoldx.2018.07.005, PubMed 30165204
  33. Rye IH, Trinh A, Saetersdal AB, Nebdal D, Lingjaerde OC, Almendro V, Polyak K, Børresen-Dale AL, Helland Å, Markowetz F, Russnes HG (2018)
    Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors
    Mol Oncol, 12 (11), 1838-1855
    DOI 10.1002/1878-0261.12375, PubMed 30133130
  34. Shen S, Zhang R, Guo Y, Loehrer E, Wei Y, Zhu Y, Yuan Q, Moran S, Fleischer T, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Su L, Chen F, Christiani DC (2018)
    A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer
    Mol Oncol, 12 (6), 913-924
    DOI 10.1002/1878-0261.12204, PubMed 29656435
  35. Sugiaman-Trapman D, Vitezic M, Jouhilahti EM, Mathelier A, Lauter G, Misra S, Daub CO, Kere J, Swoboda P (2018)
    Characterization of the human RFX transcription factor family by regulatory and target gene analysis
    BMC Genomics, 19 (1), 181
    DOI 10.1186/s12864-018-4564-6, PubMed 29510665
  36. Tahiri A, Aure MR, Kristensen VN (2018)
    MicroRNA Networks in Breast Cancer Cells
    Methods Mol Biol, 1711, 55-81
    DOI 10.1007/978-1-4939-7493-1_4, PubMed 29344885
  37. Taylor-King JP, Baratchart E, Dhawan A, Coker EA, Rye IH, Russnes H, Chapman SJ, Basanta D, Marusyk A (2018)
    Simulated ablation for detection of cells impacting paracrine signalling in histology analysis
    Math Med Biol (in press)
    DOI 10.1093/imammb/dqx022, PubMed 29452382
  38. Terkelsen T, Haakensen VD, Saldova R, Gromov P, Hansen MK, Stöckmann H, Lingjaerde OC, Børresen-Dale AL, Papaleo E, Helland Å, Rudd PM, Gromova I (2018)
    N-glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients: association with tumor biology and clinical outcome
    Mol Oncol, 12 (6), 972-990
    DOI 10.1002/1878-0261.12312, PubMed 29698574
  39. Thomsen M, Skovlund E, Sorbye H, Bolstad N, Nustad KJ, Glimelius B, Pfeiffer P, Kure EH, Johansen JS, Tveit KM, Christoffersen T, Guren TK (2018)
    Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome
    Br J Cancer, 118 (12), 1609-1616
    DOI 10.1038/s41416-018-0115-9, PubMed 29872151
  40. Tinholt M, Garred Ø, Borgen E, Beraki E, Schlichting E, Kristensen V, Sahlberg KK, Iversen N (2018)
    Subtype-specific clinical and prognostic relevance of tumor-expressed F5 and regulatory F5 variants in breast cancer: the CoCaV study
    J Thromb Haemost, 16 (7), 1347-1356
    DOI 10.1111/jth.14151, PubMed 29766637
  41. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
    Sample-Index Misassignment Impacts Tumour Exome Sequencing
    Sci Rep, 8 (1), 5307
    DOI 10.1038/s41598-018-23563-4, PubMed 29593270
  42. Wei Y, Liang J, Zhang R, Guo Y, Shen S, Su L, Lin X, Moran S, Helland Å, Bjaanæs MM, Karlsson A, Planck M, Esteller M, Fleischer T, Staaf J, Zhao Y, Chen F, Christiani DC (2018)
    Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC
    Clin Epigenetics, 10, 41
    DOI 10.1186/s13148-018-0474-3, PubMed 29619118
  43. Wu L, Shi W, Long J, Guo X, Michailidou K, Beesley J, Bolla MK, Shu XO, Lu Y, Cai Q, Al-Ejeh F, Rozali E, Wang Q, Dennis J, Li B, Zeng C, Feng H, Gusev A, Barfield RT, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Barrdahl M et al. (2018)
    A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
    Nat Genet, 50 (7), 968-978
    DOI 10.1038/s41588-018-0132-x, PubMed 29915430

Publications 2017

  1. Abravan A, Eide HA, Knudtsen IS, Løndalen AM, Helland Å, Malinen E (2017)
    Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib
    Clin Transl Radiat Oncol, 4, 57-63
    DOI 10.1016/j.ctro.2017.04.002, PubMed 29594209
  2. Abravan A, Knudtsen IS, Eide HA, Løndalen AM, Helland Å, van Luijk P, Malinen E (2017)
    A new method to assess pulmonary changes using 18F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy
    Acta Oncol, 56 (11), 1597-1603
    DOI 10.1080/0284186X.2017.1349336, PubMed 28849707
  3. Alves CP, Dey-Guha I, Kabraji S, Yeh AC, Talele NP, Solé X, Chowdhury J, Mino-Kenudson M, Loda M, Sgroi D, Borresen-Dale AL, Russnes HG, Ross KN, Ramaswamy S (2017)
    AKT1low Quiescent Cancer Cells Promote Solid Tumor Growth
    Mol Cancer Ther, 17 (1), 254-263
    DOI 10.1158/1535-7163.MCT-16-0868, PubMed 29054988
  4. Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E et al. (2017)
    Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
    Breast Cancer Res, 19 (1), 44
    DOI 10.1186/s13058-017-0812-y, PubMed 28356166
  5. Bjørklund SS, Panda A, Kumar S, Seiler M, Robinson D, Gheeya J, Yao M, Alnæs GIG, Toppmeyer D, Riis M, Naume B, Børresen-Dale AL, Kristensen VN, Ganesan S, Bhanot G (2017)
    Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma
    Sci Rep, 7 (1), 5568
    DOI 10.1038/s41598-017-05537-0, PubMed 28717182
  6. Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
    Interrogating open issues in cancer precision medicine with patient-derived xenografts
    Nat Rev Cancer, 17 (4), 254-268
    DOI 10.1038/nrc.2016.140, PubMed 28104906
  7. Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
    Interrogating open issues in cancer medicine with patient-derived xenografts
    Nat Rev Cancer, 17 (10), 632 (in press)
    DOI 10.1038/nrc.2017.85, PubMed 28912576
  8. Cheng J, Demeulemeester J, Wedge DC, Vollan HKM, Pitt JJ, Russnes HG, Pandey BP, Nilsen G, Nord S, Bignell GR, White KP, Børresen-Dale AL, Campbell PJ, Kristensen VN, Stratton MR, Lingjærde OC, Moreau Y, Van Loo P (2017)
    Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
    Nat Commun, 8 (1), 1221
    DOI 10.1038/s41467-017-01355-0, PubMed 29089486
  9. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
    Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
    Curr Pharm Des, 23 (32), 4716-4725
    DOI 10.2174/1381612823666170710154936, PubMed 28699527
  10. Cui XY, Skretting G, Tinholt M, Stavik B, Dahm AEA, Sahlberg KK, Kanse S, Iversen N, Sandset PM (2017)
    A novel hypoxia response element regulates oxygen-related repression of tissue factor pathway inhibitor in the breast cancer cell line MCF-7
    Thromb Res, 157, 111-116
    DOI 10.1016/j.thromres.2017.07.013, PubMed 28734156
  11. Dannenfelser R, Nome M, Tahiri A, Ursini-Siegel J, Vollan HKM, Haakensen VD, Helland Å, Naume B, Caldas C, Børresen-Dale AL, Kristensen VN, Troyanskaya OG (2017)
    Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity
    Oncotarget, 8 (34), 57121-57133
    DOI 10.18632/oncotarget.19078, PubMed 28915659
  12. Davies H, Glodzik D, Morganella S, Yates LR, Staaf J, Zou X, Ramakrishna M, Martin S, Boyault S, Sieuwerts AM, Simpson PT, King TA, Raine K, Eyfjord JE, Kong G, Borg Å, Birney E, Stunnenberg HG, van de Vijver MJ, Børresen-Dale AL, Martens JW, Span PN, Lakhani SR, Vincent-Salomon A, Sotiriou C et al. (2017)
    HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
    Nat Med, 23 (4), 517-525
    DOI 10.1038/nm.4292, PubMed 28288110
  13. Davies H, Morganella S, Purdie CA, Jang SJ, Borgen E, Russnes H, Glodzik D, Zou X, Viari A, Richardson AL, Børresen-Dale AL, Thompson A, Eyfjord JE, Kong G, Stratton MR, Nik-Zainal S (2017)
    Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency
    Cancer Res, 77 (18), 4755-4762
    DOI 10.1158/0008-5472.CAN-17-1083, PubMed 28904067
  14. Dumeaux V, Fjukstad B, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Børresen-Dale AL, Bongo LA, Lund E, Hallett M (2017)
    Interactions between the tumor and the blood systemic response of breast cancer patients
    PLoS Comput Biol, 13 (9), e1005680
    DOI 10.1371/journal.pcbi.1005680, PubMed 28957325
  15. Ellingjord-Dale M, Vos L, Hjerkind KV, Hjartåker A, Russnes HG, Tretli S, Hofvind S, Dos-Santos-Silva I, Ursin G (2017)
    Alcohol, Physical Activity, Smoking, and Breast Cancer Subtypes in a Large, Nested Case-Control Study from the Norwegian Breast Cancer Screening Program
    Cancer Epidemiol Biomarkers Prev, 26 (12), 1736-1744
    DOI 10.1158/1055-9965.EPI-17-0611, PubMed 28877889
  16. Euceda LR, Haukaas TH, Giskeodegard GF, Vettukattil R, Engel J, Silwal-Pandit L, Lundgren S, Borgen E, Garred O, Postma G, Buydens LMC, Borresen-Dale AL, Engebraaten O, Bathen TF (2017)
    Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
    Metabolomics, 13 (4), 37
  17. Fleischer T, Klajic J, Aure MR, Louhimo R, Pladsen AV, Ottestad L, Touleimat N, Laakso M, Halvorsen AR, Grenaker Alnæs GI, Riis ML, Helland Å, Hautaniemi S, Lønning PE, Naume B, Børresen-Dale AL, Tost J, Kristensen VN (2017)
    DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival
    Oncotarget, 8 (1), 1074-1082
    DOI 10.18632/oncotarget.13718, PubMed 27911866
  18. Fleischer T, Tekpli X, Mathelier A, Wang S, Nebdal D, Dhakal HP, Sahlberg KK, Schlichting E, Oslo Breast Cancer Research Consortium (OSBREAC), Børresen-Dale AL, Borgen E, Naume B, Eskeland R, Frigessi A, Tost J, Hurtado A, Kristensen VN (2017)
    DNA methylation at enhancers identifies distinct breast cancer lineages
    Nat Commun, 8 (1), 1379
    DOI 10.1038/s41467-017-00510-x, PubMed 29123100
  19. Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E (2017)
    ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
    Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
    DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611
  20. Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, McDonnell CH, Wagner J, Rowberry R, Freeman GJ, Dillon D, Sorlie T, Coussens LM, Garber JE, Fan R, Bobolis K et al. (2017)
    Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition
    Cancer Discov, 7 (10), 1098-1115
    DOI 10.1158/2159-8290.CD-17-0222, PubMed 28652380
  21. Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, Diez-Perez J, Staaf J, Alexandrov LB, Smid M, Brinkman AB, Rye IH, Russnes H, Raine K, Purdie CA, Lakhani SR, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL, Richardson AL, Kong G, Viari A et al. (2017)
    A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
    Nat Genet, 49 (3), 341-348
    DOI 10.1038/ng.3771, PubMed 28112740
  22. Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, Diez-Perez J, Staaf J, Alexandrov LB, Smid M, Brinkman AB, Rye IH, Russnes H, Raine K, Purdie CA, Lakhani SR, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JWM, Børresen-Dale AL, Richardson AL, Kong G, Viari A et al. (2017)
    Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
    Nat Genet, 49 (11), 1661
    DOI 10.1038/ng1117-1661a, PubMed 29074948
  23. Guo Q, Burgess S, Turman C, Bolla MK, Wang Q, Lush M, Abraham J, Aittomäki K, Andrulis IL, Apicella C, Arndt V, Barrdahl M, Benitez J, Berg CD, Blomqvist C, Bojesen SE, Bonanni B, Brand JS, Brenner H, Broeks A, Burwinkel B, Caldas C, Campa D, Canzian F, Chang-Claude J et al. (2017)
    Body mass index and breast cancer survival: a Mendelian randomization analysis
    Int J Epidemiol, 46 (6), 1814-1822
    DOI 10.1093/ije/dyx131, PubMed 29232439
  24. Guren TK, Thomsen M, Kure EH, Sorbye H, Glimelius B, Pfeiffer P, Österlund P, Sigurdsson F, Lothe IMB, Dalsgaard AM, Skovlund E, Christoffersen T, Tveit KM (2017)
    Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study
    Br J Cancer, 116 (10), 1271-1278
    DOI 10.1038/bjc.2017.93, PubMed 28399112
  25. Halle MK, Tangen IL, Berg HF, Hoivik EA, Mauland KK, Kusonmano K, Berg A, Hurtado A, Kalland KH, Øyan AM, Stefansson I, Vintermyr OK, Werner HM, Haldorsen IS, Trovik J, Salvesen HB, Krakstad C (2017)
    HER2 expression patterns in paired primary and metastatic endometrial cancer lesions
    Br J Cancer, 118 (3), 378-387
    DOI 10.1038/bjc.2017.422, PubMed 29169184
  26. Halvorsen AR, Kristensen G, Embleton A, Adusei C, Barretina-Ginesta MP, Beale P, Helland Å (2017)
    Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients
    Dis Markers, 2017, 3098542
    DOI 10.1155/2017/3098542, PubMed 28293063
  27. Helland T, Henne N, Bifulco E, Naume B, Borgen E, Kristensen VN, Kvaløy JT, Lash TL, Alnæs GIG, van Schaik RH, Janssen EAM, Hustad S, Lien EA, Mellgren G, Søiland H (2017)
    Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients
    Breast Cancer Res, 19 (1), 125
    DOI 10.1186/s13058-017-0916-4, PubMed 29183390
  28. Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
    High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
    Int J Cancer, 141 (1), 184-190
    DOI 10.1002/ijc.30726, PubMed 28387924
  29. Jernström S, Hongisto V, Leivonen SK, Due EU, Tadele DS, Edgren H, Kallioniemi O, Perälä M, Mælandsmo GM, Sahlberg KK (2017)
    Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response
    Breast Cancer (Dove Med Press), 9, 185-198
    DOI 10.2147/BCTT.S115600, PubMed 28356768
  30. Jiao X, Aravidis C, Marikkannu R, Rantala J, Picelli S, Adamovic T, Liu T, Maguire P, Kremeyer B, Luo L, von Holst S, Kontham V, Thutkawkorapin J, Margolin S, Du Q, Lundin J, Michailidou K, Bolla MK, Wang Q, Dennis J, Lush M, Ambrosone CB, Andrulis IL, Anton-Culver H, Antonenkova NN et al. (2017)
    PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1
    Oncotarget, 8 (61), 102769-102782
    DOI 10.18632/oncotarget.21800, PubMed 29262523
  31. Ju YS, Martincorena I, Gerstung M, Petljak M, Alexandrov LB, Rahbari R, Wedge DC, Davies HR, Ramakrishna M, Fullam A, Martin S, Alder C, Patel N, Gamble S, O'Meara S, Giri DD, Sauer T, Pinder SE, Purdie CA, Borg Å, Stunnenberg H, van de Vijver M, Tan BK, Caldas C, Tutt A et al. (2017)
    Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
    Nature, 543 (7647), 714-718
    DOI 10.1038/nature21703, PubMed 28329761
  32. Khan A, Mathelier A (2017)
    Intervene: a tool for intersection and visualization of multiple gene or genomic region sets
    BMC Bioinformatics, 18 (1), 287
    DOI 10.1186/s12859-017-1708-7, PubMed 28569135
  33. Kristensen VN (2017)
    The Antigenicity of the Tumor Cell - Context Matters
    N Engl J Med, 376 (5), 491-493
    DOI 10.1056/NEJMcibr1613793, PubMed 28146670
  34. Laurberg T, Tramm T, Nielsen T, Alsner J, Nord S, Myhre S, Sørlie T, Leung S, Fan C, Perou C, Gelmon K, Overgaard J, Voduc D, Prat A, Cheang MCU (2017)
    Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials
    Acta Oncol, 57 (1), 38-43
    DOI 10.1080/0284186X.2017.1401735, PubMed 29172851
  35. Leroy B, Ballinger ML, Baran-Marszak F, Bond GL, Braithwaite A, Concin N, Donehower LA, El-Deiry WS, Fenaux P, Gaidano G, Langerød A, Hellstrom-Lindberg E, Iggo R, Lehmann-Che J, Mai PL, Malkin D, Moll UM, Myers JN, Nichols KE, Pospisilova S, Ashton-Prolla P, Rossi D, Savage SA, Strong LC, Tonin PN et al. (2017)
    Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
    Cancer Res, 77 (6), 1250-1260
    DOI 10.1158/0008-5472.CAN-16-2179, PubMed 28254861
  36. Lund-Iversen M (2017)
    Digest your anatomy
    Tidsskr. Nor. Laegeforen., 137 (9), 645
  37. McGowan M, Kleinberg L, Halvorsen AR, Helland Å, Brustugun OT (2017)
    NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors
    Genes Cancer, 8 (3-4), 497-504
    DOI 10.18632/genesandcancer.136, PubMed 28680534
  38. Mezheyeuski A, Strell C, Hrynchyk I, Guren TK, Dragomir A, Doroshenko T, Pashkova O, Gorgun J, Ruksha K, Pfeiffer P, Kure EH, Sorbye H, Edler D, Martling A, Glimelius B, Östman A, Portyanko A (2017)
    Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer
    Virchows Arch, 472 (3), 395-405
    DOI 10.1007/s00428-017-2263-3, PubMed 29134439
  39. Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang Z, Allen J, Keeman R, Eilber U, French JD, Qing Chen X, Fachal L, McCue K, McCart Reed AE, Ghoussaini M et al. (2017)
    Association analysis identifies 65 new breast cancer risk loci
    Nature, 551 (7678), 92-94
    DOI 10.1038/nature24284, PubMed 29059683
  40. Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, Soucy P, Dennis J, Jiang X, Rostamianfar A, Finucane H, Bolla MK, McGuffog L, Wang Q, Aalfs CM, ABCTB Investigators, Adams M, Adlard J, Agata S, Ahmed S, Ahsan H, Aittomäki K, Al-Ejeh F et al. (2017)
    Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
    Nat Genet, 49 (12), 1767-1778
    DOI 10.1038/ng.3785, PubMed 29058716
  41. Ohnstad HO, Borgen E, Falk RS, Lien TG, Aaserud M, Sveli MAT, Kyte JA, Kristensen VN, Geitvik GA, Schlichting E, Wist EA, Sørlie T, Russnes HG, Naume B (2017)
    Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up
    Breast Cancer Res, 19 (1), 120
    DOI 10.1186/s13058-017-0911-9, PubMed 29137653
  42. Quigley DA, Tahiri A, Lüders T, Riis MH, Balmain A, Børresen-Dale AL, Bukholm I, Kristensen V (2017)
    Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue
    Oncoimmunology, 6 (11), e1356142
    DOI 10.1080/2162402X.2017.1356142, PubMed 29147603
  43. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
    Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
    ESMO Open, 2 (2), e000158
    DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
  44. Russnes HG, Lingjærde OC, Børresen-Dale AL, Caldas C (2017)
    Breast Cancer Molecular Stratification: From Intrinsic Subtypes to Integrative Clusters
    Am J Pathol, 187 (10), 2152-2162
    DOI 10.1016/j.ajpath.2017.04.022, PubMed 28733194
  45. Saldova R, Haakensen VD, Rødland E, Walsh I, Stöckmann H, Engebraaten O, Børresen-Dale AL, Rudd PM (2017)
    Serum N-glycome alterations in breast cancer during multimodal treatment and follow-up
    Mol Oncol, 11 (10), 1361-1379
    DOI 10.1002/1878-0261.12105, PubMed 28657165
  46. Samuel N, Id Said B, Guha T, Novokmet A, Li W, Silwal-Pandit L, Børrsen-Dale AL, Langerød A, Hudson TJ, Malkin D (2017)
    Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk
    Hum Mutat, 38 (3), 265-268
    DOI 10.1002/humu.23154, PubMed 27957778
  47. Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L, Martin C, Calléja FMGR, Meeks H, Hallberg E, Hinton J, Lilyquist J, Hu C, Aalfs CM, Aittomäki K, Andrulis I, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brennan P et al. (2017)
    BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer
    Cancer Res, 77 (11), 2789-2799
    DOI 10.1158/0008-5472.CAN-16-2568, PubMed 28283652
  48. Silwal-Pandit L, Langerød A, Børresen-Dale AL (2017)
    TP53 Mutations in Breast and Ovarian Cancer
    Cold Spring Harb Perspect Med, 7 (1)
    DOI 10.1101/cshperspect.a026252, PubMed 27815305
  49. Silwal-Pandit L, Nord S, von der Lippe Gythfeldt H, Møller EK, Fleischer T, Rødland E, Krohn M, Borgen E, Garred Ø, Olsen T, Vu P, Skjerven H, Fangberget A, Holmen MM, Schlitchting E, Wille E, Nordberg Stokke M, Moen Vollan HK, Kristensen V, Langerød A, Lundgren S, Wist E, Naume B, Lingjærde OC, Børresen-Dale AL et al. (2017)
    The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer
    Clin Cancer Res, 23 (16), 4662-4670
    DOI 10.1158/1078-0432.CCR-17-0160, PubMed 28487444
  50. Thomsen M, Guren MG, Skovlund E, Glimelius B, Hjermstad MJ, Johansen JS, Kure E, Sorbye H, Pfeiffer P, Christoffersen T, Guren TK, Tveit KM (2017)
    Health-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status
    Eur J Cancer, 81, 26-35
    DOI 10.1016/j.ejca.2017.04.026, PubMed 28595137
  51. Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K (2017)
    Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
    Oncotarget, 8 (44), 76290-76304
    DOI 10.18632/oncotarget.19350, PubMed 29100312

Publications 2016

  1. Brustugun OT, Sprauten M, Helland Å (2016)
    Real-world data on nivolumab treatment of non-small cell lung cancer
    Acta Oncol, 56 (3), 438-440
    DOI 10.1080/0284186X.2016.1253865, PubMed 27892773
  2. Børnich C, Grytten I, Hovig E, Paulsen J, Čech M, Sandve GK (2016)
    Galaxy Portal: interacting with the galaxy platform through mobile devices
    Bioinformatics, 32 (11), 1743-5
    DOI 10.1093/bioinformatics/btw042, PubMed 26819474
  3. Cheng TH, Thompson DJ, O'Mara TA, Painter JN, Glubb DM, Flach S, Lewis A, French JD, Freeman-Mills L, Church D, Gorman M, Martin L, National Study of Endometrial Cancer Genetics Group (NSECG), Hodgson S, Webb PM, Australian National Endometrial Cancer Study Group (ANECS), Attia J, Holliday EG, McEvoy M, Scott RJ, Henders AK, Martin NG, Montgomery GW, Nyholt DR, Ahmed S et al. (2016)
    Five endometrial cancer risk loci identified through genome-wide association analysis
    Nat Genet, 48 (6), 667-674
    DOI 10.1038/ng.3562, PubMed 27135401
  4. Couch FJ, Kuchenbaecker KB, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J, Olswold C, Hallberg E, Agata S, Ahsan H, Aittomäki K, Ambrosone C, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Barile M, Barkardottir RB, Barrowdale D, Beckmann L, Beckmann MW, Benitez J, Blank SV, Blomqvist C et al. (2016)
    Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
    Nat Commun, 7, 11375
    DOI 10.1038/ncomms11375, PubMed 27117709
  5. Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A (2016)
    Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
    Nature, 537 (7621), 548-552
    DOI 10.1038/nature19360, PubMed 27626377
  6. Darabi H, Beesley J, Droit A, Kar S, Nord S, Moradi Marjaneh M, Soucy P, Michailidou K, Ghoussaini M, Fues Wahl H, Bolla MK, Wang Q, Dennis J, Alonso MR, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Broeks A, Brüning T et al. (2016)
    Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)
    Sci Rep, 6, 32512
    DOI 10.1038/srep32512, PubMed 27600471
  7. Demeulemeester J, Kumar P, Møller EK, Nord S, Wedge DC, Peterson A, Mathiesen RR, Fjelldal R, Zamani Esteki M, Theunis K, Fernandez Gallardo E, Grundstad AJ, Borgen E, Baumbusch LO, Børresen-Dale AL, White KP, Kristensen VN, Van Loo P, Voet T, Naume B (2016)
    Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
    Genome Biol, 17 (1), 250
    DOI 10.1186/s13059-016-1109-7, PubMed 27931250
  8. Dominguez-Valentin M, Gras Navarro A, Rahman AM, Kumar S, Retière C, Ulvestad E, Kristensen V, Lund-Johansen M, Lie BA, Enger PØ, Njølstad G, Kristoffersen E, Lie SA, Chekenya M (2016)
    Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients
    Cancer Res, 76 (18), 5326-36
    DOI 10.1158/0008-5472.CAN-16-1162, PubMed 27406829
  9. Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J et al. (2016)
    Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
    Nat Genet, 48 (4), 374-86
    DOI 10.1038/ng.3521, PubMed 26928228
  10. Easton DF, Lesueur F, Decker B, Michailidou K, Li J, Allen J, Luccarini C, Pooley KA, Shah M, Bolla MK, Wang Q, Dennis J, Ahmad J, Thompson ER, Damiola F, Pertesi M, Voegele C, Mebirouk N, Robinot N, Durand G, Forey N, Luben RN, Ahmed S, Aittomäki K, Anton-Culver H et al. (2016)
    No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing
    J Med Genet, 53 (5), 298-309
    DOI 10.1136/jmedgenet-2015-103529, PubMed 26921362
  11. Eftang LL, Klajic J, Kristensen VN, Tost J, Esbensen QY, Blom GP, Bukholm IR, Bukholm G (2016)
    GFRA3 promoter methylation may be associated with decreased postoperative survival in gastric cancer
    BMC Cancer, 16, 225
    DOI 10.1186/s12885-016-2247-8, PubMed 26984265
  12. Eide HA, Halvorsen AR, Bjaanæs MM, Piri H, Holm R, Solberg S, Jørgensen L, Brustugun OT, Kiserud CE, Helland Å (2016)
    The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes
    BMC Cancer, 16, 71
    DOI 10.1186/s12885-016-2104-9, PubMed 26858029
  13. Eide HA, Halvorsen AR, Sandhu V, Fåne A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland Å (2016)
    Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
    Clin Transl Immunology, 5 (11), e109
    DOI 10.1038/cti.2016.65, PubMed 27990285
  14. Espinoza JA, Jabeen S, Batra R, Papaleo E, Haakensen V, Timmermans Wielenga V, Møller Talman ML, Brunner N, Børresen-Dale AL, Gromov P, Helland Å, Kristensen VN, Gromova I (2016)
    Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics
    Oncoimmunology, 5 (12), e1248015
    DOI 10.1080/2162402X.2016.1248015, PubMed 28123884
  15. Fiorito E, Sharma Y, Gilfillan S, Wang S, Singh SK, Satheesh SV, Katika MR, Urbanucci A, Thiede B, Mills IG, Hurtado A (2016)
    CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions
    Nucleic Acids Res, 44 (22), 10588-10602
    DOI 10.1093/nar/gkw785, PubMed 27638884
  16. Ghoussaini M, French JD, Michailidou K, Nord S, Beesley J, Canisus S, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Dennis J, Bolla MK, Wang Q, Dicks E, Milne RL, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O et al. (2016)
    Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
    Am J Hum Genet, 99 (4), 903-911
    DOI 10.1016/j.ajhg.2016.07.017, PubMed 27640304
  17. Guo Y, Warren Andersen S, Shu XO, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J, Dunning A, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bogdanova NV, Bonanni B, Børresen-Dale AL, Brand J, Brauch H et al. (2016)
    Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent
    PLoS Med, 13 (8), e1002105
    DOI 10.1371/journal.pmed.1002105, PubMed 27551723
  18. Halvorsen AR, Bjaanæs M, LeBlanc M, Holm AM, Bolstad N, Rubio L, Peñalver JC, Cervera J, Mojarrieta JC, López-Guerrero JA, Brustugun OT, Helland Å (2016)
    A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer
    Oncotarget, 7 (24), 37250-37259
    DOI 10.18632/oncotarget.9363, PubMed 27191990
  19. Halvorsen AR, Helland Å, Gromov P, Wielenga VT, Talman MM, Brunner N, Sandhu V, Børresen-Dale AL, Gromova I, Haakensen VD (2016)
    Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer
    Mol Oncol, 11 (2), 220-234
    DOI 10.1002/1878-0261.12025, PubMed 28145100
  20. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    DOI 10.3389/fgene.2016.00085, PubMed 27242894
  21. Hamdi Y, Soucy P, Adoue V, Michailidou K, Canisius S, Lemaçon A, Droit A, Andrulis IL, Anton-Culver H, Arndt V, Baynes C, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Borresen-Dale AL, Brand JS, Brauch H, Brenner H, Broeks A, Burwinkel B, Chang-Claude J, NBCS Collaborators, Couch FJ et al. (2016)
    Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21
    Oncotarget, 7 (49), 80140-80163
    DOI 10.18632/oncotarget.12818, PubMed 27792995
  22. Hamdi Y, Soucy P, Kuchenbaeker KB, Pastinen T, Droit A, Lemaçon A, Adlard J, Aittomäki K, Andrulis IL, Arason A, Arnold N, Arun BK, Azzollini J, Bane A, Barjhoux L, Barrowdale D, Benitez J, Berthet P, Blok MJ, Bobolis K, Bonadona V, Bonanni B, Bradbury AR, Brewer C, Buecher B et al. (2016)
    Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3
    Breast Cancer Res Treat, 161 (1), 117-134
    DOI 10.1007/s10549-016-4018-2, PubMed 27796716
  23. Haukaas TH, Euceda LR, Giskeødegård GF, Lamichhane S, Krohn M, Jernström S, Aure MR, Lingjærde OC, Schlichting E, Garred Ø, Due EU, Mills GB, Sahlberg KK, Børresen-Dale AL, Bathen TF, Oslo Breast Cancer Consortium (OSBREAC) (2016)
    Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes
    Cancer Metab, 4, 12
    DOI 10.1186/s40170-016-0152-x, PubMed 27350877
  24. Helland A (2016)
    MicroRNA-profiles in lung adenocarcinomas
    Expert Rev. Precis. Med. Drug Dev., 1 (5), 469-474
  25. Horne HN, Chung CC, Zhang H, Yu K, Prokunina-Olsson L, Michailidou K, Bolla MK, Wang Q, Dennis J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O, Johnson N, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P, Truong T et al. (2016)
    Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus
    PLoS One, 11 (8), e0160316
    DOI 10.1371/journal.pone.0160316, PubMed 27556229
  26. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  27. Joly-Battaglini A, Hammarström C, Stankovic B, Aamodt H, Stjärne J, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2016)
    Rituximab efficiently depletes B cells in lung tumors and normal lung tissue
    F1000Res, 5, 38
    DOI 10.12688/f1000research.7599.1, PubMed 27081474
  28. Kar SP, Beesley J, Amin Al Olama A, Michailidou K, Tyrer J, Kote-Jarai Z, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ, ABCTB Investigators, Kibel AS, Dansonka-Mieszkowska A, Michael A, Dieffenbach AK, Gentry-Maharaj A, Whittemore AS, Wolk A, Monteiro A, Peixoto A, Kierzek A, Cox A, Rudolph A, Gonzalez-Neira A, Wu AH et al. (2016)
    Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types
    Cancer Discov, 6 (9), 1052-67
    DOI 10.1158/2159-8290.CD-15-1227, PubMed 27432226
  29. Kaveh F, Baumbusch LO, Nebdal D, Børresen-Dale AL, Lingjærde OC, Edvardsen H, Kristensen VN, Solvang HK (2016)
    A systematic comparison of copy number alterations in four types of female cancer
    BMC Cancer, 16 (1), 913
    DOI 10.1186/s12885-016-2899-4, PubMed 27876019
  30. Kleibl Z, Kristensen VN (2016)
    Women at high risk of breast cancer: Molecular characteristics, clinical presentation and management
    Breast, 28, 136-44
    DOI 10.1016/j.breast.2016.05.006, PubMed 27318168
  31. Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Bandera EV, Barile M, Barkardottir RB, Barrowdale D, Beckmann MW, Benitez J, Berchuck A, Bisogna M et al. (2016)
    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
    Nat Commun, 7, 12675
    DOI 10.1038/ncomms12675, PubMed 27601076
  32. Lesurf R, Aure MR, Mørk HH, Vitelli V, Oslo Breast Cancer Research Consortium (OSBREAC), Lundgren S, Børresen-Dale AL, Kristensen V, Wärnberg F, Hallett M, Sørlie T (2016)
    Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer
    Cell Rep, 16 (4), 1166-1179
    DOI 10.1016/j.celrep.2016.06.051, PubMed 27396337
  33. Lindstad T, Qu S, Sikkeland J, Jin Y, Kristian A, Mælandsmo GM, Collas P, Saatcioglu F (2016)
    STAMP2 is required for human adipose-derived stem cell differentiation and adipocyte-facilitated prostate cancer growth in vivo
    Oncotarget, 8 (54), 91817-91827
    DOI 10.18632/oncotarget.11131, PubMed 29190878
  34. Liu J, Lončar I, Collée JM, Bolla MK, Dennis J, Michailidou K, Wang Q, Andrulis IL, Barile M, Beckmann MW, Behrens S, Benitez J, Blomqvist C, Boeckx B, Bogdanova NV, Bojesen SE, Brauch H, Brennan P, Brenner H, Broeks A, Burwinkel B, Chang-Claude J, Chen ST, Chenevix-Trench G, Cheng CY et al. (2016)
    rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk
    Sci Rep, 6, 36874
    DOI 10.1038/srep36874, PubMed 27845421
  35. Lizio M, Harshbarger J, Abugessaisa I, Noguchi S, Kondo A, Severin J, Mungall C, Arenillas D, Mathelier A, Medvedeva YA, Lennartsson A, Drabløs F, Ramilowski JA, Rackham O, Gough J, Andersson R, Sandelin A, Ienasescu H, Ono H, Bono H, Hayashizaki Y, Carninci P, Forrest AR, Kasukawa T, Kawaji H (2016)
    Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals
    Nucleic Acids Res, 45 (D1), D737-D743
    DOI 10.1093/nar/gkw995, PubMed 27794045
  36. Mathelier A, Xin B, Chiu TP, Yang L, Rohs R, Wasserman WW (2016)
    DNA Shape Features Improve Transcription Factor Binding Site Predictions In Vivo
    Cell Syst, 3 (3), 278-286.e4
    DOI 10.1016/j.cels.2016.07.001, PubMed 27546793
  37. McGowan M, Hoven AS, Lund-Iversen M, Solberg S, Helland Å, Hirsch FR, Brustugun OT (2016)
    PIK3CA mutations as prognostic factor in squamous cell lung carcinoma
    Lung Cancer, 103, 52-57
    DOI 10.1016/j.lungcan.2016.11.018, PubMed 28024696
  38. Mezheyeuski A, Bradic Lindh M, Guren TK, Dragomir A, Pfeiffer P, Kure EH, Ikdahl T, Skovlund E, Corvigno S, Strell C, Pietras K, Ponten F, Mulder J, Qvortrup C, Portyanko A, Tveit KM, Glimelius B, Sorbye H, Östman A (2016)
    Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer
    Oncotarget, 7 (27), 41948-41958
    DOI 10.18632/oncotarget.9632, PubMed 27248825
  39. Morganella S, Alexandrov LB, Glodzik D, Zou X, Davies H, Staaf J, Sieuwerts AM, Brinkman AB, Martin S, Ramakrishna M, Butler A, Kim HY, Borg Å, Sotiriou C, Futreal PA, Campbell PJ, Span PN, Van Laere S, Lakhani SR, Eyfjord JE, Thompson AM, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL et al. (2016)
    The topography of mutational processes in breast cancer genomes
    Nat Commun, 7, 11383
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  40. Muranen TA, Greco D, Blomqvist C, Aittomäki K, Khan S, Hogervorst F, Verhoef S, Pharoah PDP, Dunning AM, Shah M, Luben R, Bojesen SE, Nordestgaard BG, Schoemaker M, Swerdlow A, García-Closas M, Figueroa J, Dörk T, Bogdanova NV, Hall P, Li J, Khusnutdinova E, Bermisheva M, Kristensen V, Borresen-Dale AL et al. (2016)
    Genetic modifiers of CHEK2*1100delC-associated breast cancer risk
    Genet Med, 19 (5), 599-603
    DOI 10.1038/gim.2016.147, PubMed 27711073
  41. Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D, Zou X, Martincorena I, Alexandrov LB, Martin S, Wedge DC, Van Loo P, Ju YS, Smid M, Brinkman AB, Morganella S, Aure MR, Lingjærde OC, Langerød A, Ringnér M, Ahn SM, Boyault S, Brock JE, Broeks A, Butler A, Desmedt C et al. (2016)
    Landscape of somatic mutations in 560 breast cancer whole-genome sequences
    Nature, 534 (7605), 47-54
    DOI 10.1038/nature17676, PubMed 27135926
  42. Nunes-Xavier CE, Karlsen KF, Tekle C, Pedersen C, Øyjord T, Hongisto V, Nesland JM, Tan M, Sahlberg KK, Fodstad Ø (2016)
    Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
    Oncotarget, 7 (6), 6891-901
    DOI 10.18632/oncotarget.6902, PubMed 26771843
  43. Painter JN, O'Mara TA, Marquart L, Webb PM, Attia J, Medland SE, Cheng T, Dennis J, Holliday EG, McEvoy M, Scott RJ, Ahmed S, Healey CS, Shah M, Gorman M, Martin L, Hodgson SV, Beckmann MW, Ekici AB, Fasching PA, Hein A, Rübner M, Czene K, Darabi H, Hall P et al. (2016)
    Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
    Cancer Epidemiol Biomarkers Prev, 25 (11), 1503-1510
    DOI 10.1158/1055-9965.EPI-16-0147, PubMed 27550749
  44. Papp J, Kovacs ME, Matrai Z, Orosz E, Kásler M, Børresen-Dale AL, Olah E (2016)
    Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary
    Fam Cancer, 15 (1), 85-97
    DOI 10.1007/s10689-015-9845-5, PubMed 26446593
  45. Pelttari LM, Khan S, Vuorela M, Kiiski JI, Vilske S, Nevanlinna V, Ranta S, Schleutker J, Winqvist R, Kallioniemi A, Dörk T, Bogdanova NV, Figueroa J, Pharoah PD, Schmidt MK, Dunning AM, García-Closas M, Bolla MK, Dennis J, Michailidou K, Wang Q, Hopper JL, Southey MC, Rosenberg EH, Fasching PA et al. (2016)
    RAD51B in Familial Breast Cancer
    PLoS One, 11 (5), e0153788
    DOI 10.1371/journal.pone.0153788, PubMed 27149063
  46. Pereira B, Chin SF, Rueda OM, Vollan HK, Provenzano E, Bardwell HA, Pugh M, Jones L, Russell R, Sammut SJ, Tsui DW, Liu B, Dawson SJ, Abraham J, Northen H, Peden JF, Mukherjee A, Turashvili G, Green AR, McKinney S, Oloumi A, Shah S, Rosenfeld N, Murphy L, Bentley DR et al. (2016)
    The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes
    Nat Commun, 7, 11479
    DOI 10.1038/ncomms11479, PubMed 27161491
  47. Petridis C, Brook MN, Shah V, Kohut K, Gorman P, Caneppele M, Levi D, Papouli E, Orr N, Cox A, Cross SS, Dos-Santos-Silva I, Peto J, Swerdlow A, Schoemaker MJ, Bolla MK, Wang Q, Dennis J, Michailidou K, Benitez J, González-Neira A, Tessier DC, Vincent D, Li J, Figueroa J et al. (2016)
    Genetic predisposition to ductal carcinoma in situ of the breast
    Breast Cancer Res, 18 (1), 22
    DOI 10.1186/s13058-016-0675-7, PubMed 26884359
  48. Quigley DA, Kandyba E, Huang P, Halliwill KD, Sjölund J, Pelorosso F, Wong CE, Hirst GL, Wu D, Delrosario R, Kumar A, Balmain A (2016)
    Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer
    Cell Rep, 16 (4), 1153-1165
    DOI 10.1016/j.celrep.2016.06.061, PubMed 27425619
  49. Reinertsen KV, Engebraaten O, Loge JH, Cvancarova M, Naume B, Wist E, Edvardsen H, Wille E, Bjøro T, Kiserud CE (2016)
    Fatigue During and After Breast Cancer Therapy-A Prospective Study
    J Pain Symptom Manage, 53 (3), 551-560
    DOI 10.1016/j.jpainsymman.2016.09.011, PubMed 28042070
  50. Robles AI, Olsen KS, Tsui DW, Georgoulias V, Creaney J, Dobra K, Vyberg M, Minato N, Anders RA, Børresen-Dale AL, Zhou J, Sætrom P, Nielsen BS, Kirschner MB, Krokan HE, Papadimitrakopoulou V, Tsamardinos I, Røe OD (2016)
    Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway
    J Transl Med, 14 (1), 295
    DOI 10.1186/s12967-016-1059-6, PubMed 27756323
  51. Rowczenio D, Stensland M, de Souza GA, Strøm EH, Gilbertson JA, Taylor G, Rendell N, Minogue S, Efebera YA, Lachmann HJ, Wechalekar AD, Hawkins PN, Heimdal KR, Selvig K, Lægreid IK, Demoulin N, Aydin S, Gillmore JD, Wien TN (2016)
    Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein
    Kidney Int Rep, 2 (3), 461-469
    DOI 10.1016/j.ekir.2016.11.005, PubMed 29142973
  52. Rud AK, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM (2016)
    Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
    Diagn Pathol, 11 (1), 50
    DOI 10.1186/s13000-016-0504-4, PubMed 27316334
  53. Sandhu V, Wedge DC, Bowitz Lothe IM, Labori KJ, Dentro SC, Buanes T, Skrede ML, Dalsgaard AM, Munthe E, Myklebost O, Lingjærde OC, Børresen-Dale AL, Ikdahl T, Van Loo P, Nord S, Kure EH (2016)
    The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
    Cancer Res, 76 (17), 5092-102
    DOI 10.1158/0008-5472.CAN-16-0658, PubMed 27488532
  54. Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Körner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F, Oslo Breast Cancer Research Consortium (OSBREAC)SauerTorillGeislerJürgenHofvindSolveigBathenTone FBorgenElinEngebråtenOlavFodstadØysteinGarredØysteinGeitvikGry AarumKåresenRolfNaumeBjørnMælandsmoGunhild MariRussnesHege GSchlichtingEllenSørlieThere, Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Børresen-Dale AL, Yarden Y (2016)
    LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer
    EMBO Mol Med, 8 (9), 1052-64
    DOI 10.15252/emmm.201606198, PubMed 27485121
  55. Shi J, Zhang Y, Zheng W, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Dennis J, Lush M, Milne RL, Shu XO, Beesley J, Kar S, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Zhao Z, Guo X, Benitez J, Beeghly-Fadiel A, Blot W, Bogdanova NV, Bojesen SE, Brauch H et al. (2016)
    Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer
    Int J Cancer, 139 (6), 1303-1317
    DOI 10.1002/ijc.30150, PubMed 27087578
  56. Shlien A, Raine K, Fuligni F, Arnold R, Nik-Zainal S, Dronov S, Mamanova L, Rosic A, Ju YS, Cooke SL, Ramakrishna M, Papaemmanuil E, Davies HR, Tarpey PS, Van Loo P, Wedge DC, Jones DR, Martin S, Marshall J, Anderson E, Hardy C, ICGC Breast Cancer Working Group, Oslo Breast Cancer Research Consortium, Barbashina V, Aparicio SA, Sauer T et al. (2016)
    Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
    Cell Rep, 16 (7), 2032-46
    DOI 10.1016/j.celrep.2016.07.028, PubMed 27498871
  57. Smid M, Rodríguez-González FG, Sieuwerts AM, Salgado R, Prager-Van der Smissen WJ, Vlugt-Daane MV, van Galen A, Nik-Zainal S, Staaf J, Brinkman AB, van de Vijver MJ, Richardson AL, Fatima A, Berentsen K, Butler A, Martin S, Davies HR, Debets R, Gelder ME, van Deurzen CH, MacGrogan G, Van den Eynden GG, Purdie C, Thompson AM, Caldas C et al. (2016)
    Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration
    Nat Commun, 7, 12910
    DOI 10.1038/ncomms12910, PubMed 27666519
  58. Solvang HK, Frigessi A, Kaveh F, Riis ML, Lüders T, Bukholm IR, Kristensen VN, Andreassen BK (2016)
    Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer
    EURASIP J Bioinform Syst Biol, 2016 (1), 6
    DOI 10.1186/s13637-015-0034-5, PubMed 26900390
  59. Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ, Heikkinen T, Nevanlinna H, Hopper JL, Dörk T, Claes KB, Reis-Filho J, Teo ZL, Radice P, Catucci I, Peterlongo P, Tsimiklis H, Odefrey FA, Dowty JG, Schmidt MK, Broeks A et al. (2016)
    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
    J Med Genet, 53 (12), 800-811
    DOI 10.1136/jmedgenet-2016-103839, PubMed 27595995
  60. Sørlie T (2016)
    The Impact of Gene Expression Patterns in Breast Cancer
    Clin Chem, 62 (8), 1150-1
    DOI 10.1373/clinchem.2015.253229, PubMed 27022070
  61. Tarpgaard LS, Ørum-Madsen MS, Christensen IJ, Nordgaard C, Noer J, Guren TK, Glimelius B, Sorbye H, Ikdahl T, Kure EH, Tveit KM, Nielsen HJ, Pfeiffer P, Brünner N, Moreira JM (2016)
    TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer
    Oncotarget, 7 (37), 59441-59457
    DOI 10.18632/oncotarget.11118, PubMed 27509063
  62. Tekpli X, Skaug V, Bæra R, Phillips DH, Haugen A, Mollerup S (2016)
    Estrogen receptor expression and gene promoter methylation in non-small cell lung cancer - a short report
    Cell Oncol (Dordr), 39 (6), 583-589
    DOI 10.1007/s13402-016-0295-3, PubMed 27572263
  63. Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
    Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
    Epigenetics Chromatin, 9, 21
    DOI 10.1186/s13072-016-0070-8, PubMed 27252783
  64. Thienpont B, Steinbacher J, Zhao H, D'Anna F, Kuchnio A, Ploumakis A, Ghesquière B, Van Dyck L, Boeckx B, Schoonjans L, Hermans E, Amant F, Kristensen VN, Peng Koh K, Mazzone M, Coleman M, Carell T, Carmeliet P, Lambrechts D (2016)
    Tumour hypoxia causes DNA hypermethylation by reducing TET activity
    Nature, 537 (7618), 63-68
    DOI 10.1038/nature19081, PubMed 27533040
  65. Thomsen M, Kersten C, Sorbye H, Skovlund E, Glimelius B, Pfeiffer P, Johansen JS, Kure EH, Ikdahl T, Tveit KM, Christoffersen T, Guren TK (2016)
    Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer
    Oncotarget, 7 (46), 75013-75022
    DOI 10.18632/oncotarget.12601, PubMed 27738330
  66. Tinholt M, Sandset PM, Mowinckel MC, Garred Ø, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Jacobsen AF, Skretting G, Iversen N (2016)
    Determinants of acquired activated protein C resistance and D-dimer in breast cancer
    Thromb Res, 145, 78-83
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  67. Weischenfeldt J, Dubash T, Drainas AP, Mardin BR, Chen Y, Stütz AM, Waszak SM, Bosco G, Halvorsen AR, Raeder B, Efthymiopoulos T, Erkek S, Siegl C, Brenner H, Brustugun OT, Dieter SM, Northcott PA, Petersen I, Pfister SM, Schneider M, Solberg SK, Thunissen E, Weichert W, Zichner T, Thomas R et al. (2016)
    Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
    Nat Genet, 49 (1), 65-74
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  68. Wyszynski A, Hong CC, Lam K, Michailidou K, Lytle C, Yao S, Zhang Y, Bolla MK, Wang Q, Dennis J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Peto J, Dos-Santos-Silva I, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P et al. (2016)
    An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression
    Hum Mol Genet, 25 (17), 3863-3876
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    Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
    Breast Cancer Res, 18 (1), 64
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    Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry
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Publications 2015

  1. Alnaes GI, Ronneberg JA, Kristensen VN, Tost J (2015)
    Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer
    Genes (Basel), 6 (3), 878-900
    DOI 10.3390/genes6030878, PubMed 26393654
  2. Andersen V, Vogel LK, Kopp TI, Sæbø M, Nonboe AW, Hamfjord J, Kure EH, Vogel U (2015)
    High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence
    PLoS One, 10 (3), e0119255
    DOI 10.1371/journal.pone.0119255, PubMed 25793771
  3. Aure MR, Jernström S, Krohn M, Vollan HK, Due EU, Rødland E, Kåresen R, Oslo Breast Cancer Research Consortium (OSBREAC), Ram P, Lu Y, Mills GB, Sahlberg KK, Børresen-Dale AL, Lingjærde OC, Kristensen VN (2015)
    Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer
    Genome Med, 7 (1), 21
    DOI 10.1186/s13073-015-0135-5, PubMed 25873999
  4. Baekelandt BM, Hjermstad MJ, Nordby T, Fagerland MW, Kure EH, Heiberg T, Buanes T, Labori KJ (2015)
    Preoperative cognitive function predicts survival in patients with resectable pancreatic ductal adenocarcinoma
    HPB (Oxford), 18 (3), 247-54
    DOI 10.1016/j.hpb.2015.09.004, PubMed 27017164
  5. Berg J, Fjellbirkeland L, Suhrke P, Jebsen P, Lund-Iversen M, Kleinberg L, Helgeland L, Brustugun OT, Helland Å (2015)
    EGFR mutation testing of lung cancer patients - Experiences from Vestfold Hospital Trust
    Acta Oncol, 55 (2), 149-55
    DOI 10.3109/0284186X.2015.1062537, PubMed 26313507
  6. Bjørklund SS, Kristensen VN, Seiler M, Kumar S, Alnæs GI, Ming Y, Kerrigan J, Naume B, Sachidanandam R, Bhanot G, Børresen-Dale AL, Ganesan S (2015)
    Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas
    BMC Cancer, 15, 524
    DOI 10.1186/s12885-015-1510-8, PubMed 26183823
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    Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
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    The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); a population-based cohort study
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    Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1
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    Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
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    Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression
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    Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair EDITORIAL COMMENT
    Obstet. Gynecol. Surv., 70 (12), 758-762
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    Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
    Nat Genet, 47 (11), 1294-1303
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    Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer
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    Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer
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    Identification of novel genetic markers of breast cancer survival
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    Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk
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    Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes
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    Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer
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    AGXT and ERCC2 polymorphisms are associated with clinical outcome in metastatic colorectal cancer patients treated with 5-FU/oxaliplatin
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    Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
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    Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium
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    Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy
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    Prediction of breast cancer risk based on profiling with common genetic variants
    J Natl Cancer Inst, 107 (5)
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    BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
    J Natl Cancer Inst, 108 (2)
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  38. Michailidou K, Beesley J, Lindstrom S, Canisius S, Dennis J, Lush MJ, Maranian MJ, Bolla MK, Wang Q, Shah M, Perkins BJ, Czene K, Eriksson M, Darabi H, Brand JS, Bojesen SE, Nordestgaard BG, Flyger H, Nielsen SF, Rahman N, Turnbull C, BOCS, Fletcher O, Peto J, Gibson L et al. (2015)
    Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
    Nat Genet, 47 (4), 373-80
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  39. Mäki-Jouppila JH, Pruikkonen S, Tambe MB, Aure MR, Halonen T, Salmela AL, Laine L, Børresen-Dale AL, Kallio MJ (2015)
    MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase
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    Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors
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    A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5
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    Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
    Endocr Relat Cancer, 22 (5), 851-61
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    Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2
    Hum Mol Genet, 24 (10), 2966-84
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    No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
    Gynecol Oncol, 141 (2), 386-401
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    Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells
    Genes Dev, 29 (12), 1298-315
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    Common germline polymorphisms associated with breast cancer-specific survival
    Breast Cancer Res, 17, 58
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    Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
    Mol Oncol, 9 (4), 861-76
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    Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells
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    Differential expression of miRNAs in pancreatobiliary type of periampullary adenocarcinoma and its associated stroma
    Mol Oncol, 10 (2), 303-16
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    A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients
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    The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer
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    From autonomy to community; new perspectives on tumorigenicity and therapy resistance
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    Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures
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Publications 2014

  1. Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K (2014)
    Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity
    Cell Rep, 6 (3), 514-27
    DOI 10.1016/j.celrep.2013.12.041, PubMed 24462293
  2. Askautrud HA, Gjernes E, Gunnes G, Sletten M, Ross DT, Børresen-Dale AL, Iversen N, Tranulis MA, Frengen E (2014)
    Global gene expression analysis reveals a link between NDRG1 and vesicle transport
    PLoS One, 9 (1), e87268
    DOI 10.1371/journal.pone.0087268, PubMed 24498060
  3. Bjaanaes MM, Halvorsen AR, Solberg S, Jørgensen L, Dragani TA, Galvan A, Colombo F, Anderlini M, Pastorino U, Kure E, Børresen-Dale AL, Brustugun OT, Helland A (2014)
    Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
    Int J Cancer, 135 (8), 1812-21
    DOI 10.1002/ijc.28828, PubMed 24599520
  4. Carvajal-Carmona LG, O'Mara TA, Painter JN, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Pooley K, Beesley J, Cheng T, Jones A, Howarth K, Martin L, Gorman M, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), Australian National Endometrial Cancer Study Group (ANECS), Wentzensen N, Fasching PA, Hein A, Beckmann MW, Renner SP et al. (2014)
    Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
    Hum Genet, 134 (2), 231-45
    DOI 10.1007/s00439-014-1515-4, PubMed 25487306
  5. Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K et al. (2014)
    Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers
    Cancer Cell, 26 (6), 863-879
    DOI 10.1016/j.ccell.2014.10.010, PubMed 25490449
  6. Fleischer T, Edvardsen H, Solvang HK, Daviaud C, Naume B, Børresen-Dale AL, Kristensen VN, Tost J (2014)
    Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients
    Int J Cancer, 134 (11), 2615-25
    DOI 10.1002/ijc.28606, PubMed 24395279
  7. Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis ML, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
    Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
    Genome Biol, 15 (8), 435
    DOI 10.1186/PREACCEPT-2333349012841587, PubMed 25146004
  8. Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE et al. (2014)
    Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
    Nat Commun, 4, 4999
    DOI 10.1038/ncomms5999, PubMed 25248036
  9. Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, O'Reilly M, Betts JA, Hillman KM, Kaufmann S, Beesley J, Canisius S, Hopper JL, Southey MC, Tsimiklis H, Apicella C, Schmidt MK, Broeks A, Hogervorst FB, van der Schoot CE, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P et al. (2014)
    Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1
    Am J Hum Genet, 96 (1), 5-20
    DOI 10.1016/j.ajhg.2014.11.009, PubMed 25529635
  10. Grinde MT, Skrbo N, Moestue SA, Rødland EA, Borgan E, Kristian A, Sitter B, Bathen TF, Børresen-Dale AL, Mælandsmo GM, Engebraaten O, Sørlie T, Marangoni E, Gribbestad IS (2014)
    Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
    Breast Cancer Res, 16 (1), R5
    DOI 10.1186/bcr3597, PubMed 24447408
  11. Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H (2014)
    Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
    Int J Cancer, 135 (9), 2085-95
    DOI 10.1002/ijc.28862, PubMed 24658971
  12. Hongisto V, Aure MR, Mäkelä R, Sahlberg KK (2014)
    The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells - A data description
    Genom Data, 2, 249-53
    DOI 10.1016/j.gdata.2014.06.025, PubMed 26484103
  13. Johnson N, Dudbridge F, Orr N, Gibson L, Jones ME, Schoemaker MJ, Folkerd EJ, Haynes BP, Hopper JL, Southey MC, Dite GS, Apicella C, Schmidt MK, Broeks A, Van't Veer LJ, Atsma F, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Ekici AB, Renner SP, Sawyer E, Tomlinson I, Kerin M et al. (2014)
    Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study
    Breast Cancer Res, 16 (3), R51
    DOI 10.1186/bcr3662, PubMed 24887515
  14. Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, dos Santos Silva I, Johnson N, Gibson L et al. (2014)
    MicroRNA related polymorphisms and breast cancer risk
    PLoS One, 9 (11), e109973
    DOI 10.1371/journal.pone.0109973, PubMed 25390939
  15. Kjersem JB, Skovlund E, Ikdahl T, Guren T, Kersten C, Dalsgaard AM, Yilmaz MK, Fokstuen T, Tveit KM, Kure EH (2014)
    FCGR2A and FCGR3A polymorphisms and clinical outcome in metastatic colorectal cancer patients treated with first-line 5-fluorouracil/folinic acid and oxaliplatin +/- cetuximab
    BMC Cancer, 14, 340
    DOI 10.1186/1471-2407-14-340, PubMed 24884501
  16. Klajic J, Busato F, Edvardsen H, Touleimat N, Fleischer T, Bukholm I, Børresen-Dale AL, Lønning PE, Tost J, Kristensen VN (2014)
    DNA methylation status of key cell-cycle regulators such as CDKNA2/p16 and CCNA1 correlates with treatment response to doxorubicin and 5-fluorouracil in locally advanced breast tumors
    Clin Cancer Res, 20 (24), 6357-66
    DOI 10.1158/1078-0432.CCR-14-0297, PubMed 25294903
  17. Kleivi Sahlberg K, Bottai G, Naume B, Burwinkel B, Calin GA, Børresen-Dale AL, Santarpia L (2014)
    A serum microRNA signature predicts tumor relapse and survival in triple-negative breast cancer patients
    Clin Cancer Res, 21 (5), 1207-14
    DOI 10.1158/1078-0432.CCR-14-2011, PubMed 25547678
  18. Kristensen VN, Lingjærde OC, Russnes HG, Vollan HK, Frigessi A, Børresen-Dale AL (2014)
    Principles and methods of integrative genomic analyses in cancer
    Nat Rev Cancer, 14 (5), 299-313
    DOI 10.1038/nrc3721, PubMed 24759209
  19. Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PD, Michailidou K, Dennis J, Bolla MK, Wang Q, Van 't Veer LJ, Cornelissen S, Rutgers E, Southey MC, Apicella C, Dite GS, Hopper JL, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Blomqvist C, Muranen TA, Aittomäki K, Lindblom A et al. (2014)
    2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
    Nat Commun, 5, 4051
    DOI 10.1038/ncomms5051, PubMed 24937182
  20. Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N et al. (2014)
    Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
    Hum Mol Genet, 24 (1), 285-98
    DOI 10.1093/hmg/ddu431, PubMed 25168388
  21. Norum JH, Andersen K, Sørlie T (2014)
    Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
    Br J Surg, 101 (8), 925-38
    DOI 10.1002/bjs.9562, PubMed 24849143
  22. Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK (2014)
    Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
    Br J Cancer, 110 (8), 2072-80
    DOI 10.1038/bjc.2014.113, PubMed 24577056
  23. Painter JN, O'Mara TA, Batra J, Cheng T, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Kaufmann S, Hillman KM, Walpole C, Moya L, Pollock P, Jones A, Howarth K, Martin L, Gorman M, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), CHIBCHA Consortium, De Polanco MM, Sans M et al. (2014)
    Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk
    Hum Mol Genet, 24 (5), 1478-92
    DOI 10.1093/hmg/ddu552, PubMed 25378557
  24. Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow A, Kristensen V, Guénel P, Meindl A, Darabi H et al. (2014)
    Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
    Hum Mol Genet, 23 (22), 6034-46
    DOI 10.1093/hmg/ddu300, PubMed 24927736
  25. Quigley D (2014)
    RNA-seq permits a closer look at normal skin and psoriasis gene networks
    J Invest Dermatol, 134 (7), 1789-1791
    DOI 10.1038/jid.2014.66, PubMed 24924757
  26. Quigley D, Silwal-Pandit L, Dannenfelser R, Langerød A, Vollan HK, Vaske C, Siegel JU, Troyanskaya O, Chin SF, Caldas C, Balmain A, Børresen-Dale AL, Kristensen V (2014)
    Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53
    Mol Cancer Res, 13 (3), 493-501
    DOI 10.1158/1541-7786.MCR-14-0387, PubMed 25351767
  27. Reiche K, Kasack K, Schreiber S, Lüders T, Due EU, Naume B, Riis M, Kristensen VN, Horn F, Børresen-Dale AL, Hackermüller J, Baumbusch LO (2014)
    Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes
    PLoS One, 9 (9), e106076
    DOI 10.1371/journal.pone.0106076, PubMed 25264628
  28. Russnes HG, Caldas C (2014)
    eEF2K--a new target in breast cancers with combined inactivation of p53 and PTEN
    EMBO Mol Med, 6 (12), 1512-4
    DOI 10.15252/emmm.201404683, PubMed 25471453
  29. Russnes HG, Lønning PE, Børresen-Dale AL, Lingjærde OC (2014)
    The multitude of molecular analyses in cancer: the opening of Pandora’s box
    Genome Biol, 15 (9), 447
    DOI 10.1186/s13059-014-0447-6, PubMed 25316146
  30. Rye IH, Lundin P, Månér S, Fjelldal R, Naume B, Wigler M, Hicks J, Børresen-Dale AL, Zetterberg A, Russnes HG (2014)
    Quantitative multigene FISH on breast carcinomas identifies der(1;16)(q10;p10) as an early event in luminal A tumors
    Genes Chromosomes Cancer, 54 (4), 235-48
    DOI 10.1002/gcc.22237, PubMed 25546585
  31. Saldova R, Asadi Shehni A, Haakensen VD, Steinfeld I, Hilliard M, Kifer I, Helland A, Yakhini Z, Børresen-Dale AL, Rudd PM (2014)
    Association of N-glycosylation with breast carcinoma and systemic features using high-resolution quantitative UPLC
    J Proteome Res, 13 (5), 2314-27
    DOI 10.1021/pr401092y, PubMed 24669823
  32. Sandhu V, Bowitz Lothe IM, Labori KJ, Lingjærde OC, Buanes T, Dalsgaard AM, Skrede ML, Hamfjord J, Haaland T, Eide TJ, Børresen-Dale AL, Ikdahl T, Kure EH (2014)
    Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
    Mol Oncol, 9 (4), 758-71
    DOI 10.1016/j.molonc.2014.12.002, PubMed 25579086
  33. Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hopper JL, Provenzano E et al. (2014)
    Genetic predisposition to in situ and invasive lobular carcinoma of the breast
    PLoS Genet, 10 (4), e1004285
    DOI 10.1371/journal.pgen.1004285, PubMed 24743323
  34. Silwal-Pandit L, Vollan HK, Chin SF, Rueda OM, McKinney S, Osako T, Quigley DA, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Langerød A (2014)
    TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
    Clin Cancer Res, 20 (13), 3569-80
    DOI 10.1158/1078-0432.CCR-13-2943, PubMed 24803582
  35. Skrbo N, Hjortland GO, Kristian A, Holm R, Nord S, Prasmickaite L, Engebraaten O, Mælandsmo GM, Sørlie T, Andersen K (2014)
    Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft
    PLoS One, 9 (11), e113278
    DOI 10.1371/journal.pone.0113278, PubMed 25419568
  36. Sternemalm J, Russnes HG, Zhao X, Risberg B, Nord S, Caldas C, Børresen-Dale AL, Stokke T, Patzke S (2014)
    Nuclear CSPP1 expression defined subtypes of basal-like breast cancer
    Br J Cancer, 111 (2), 326-38
    DOI 10.1038/bjc.2014.297, PubMed 24901235
  37. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
    Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
    Methods Mol Biol, 1105, 315-24
    DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239
  38. Tarpgaard LS, Guren TK, Glimelius B, Christensen IJ, Pfeiffer P, Kure EH, Sorbye H, Ikdahl T, Yilmaz M, Johansen JS, Tveit KM (2014)
    Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study
    PLoS One, 9 (2), e87746
    DOI 10.1371/journal.pone.0087746, PubMed 24498368
  39. Tinholt M, Viken MK, Dahm AE, Vollan HK, Sahlberg KK, Garred O, Børresen-Dale AL, Jacobsen AF, Kristensen V, Bukholm I, Kåresen R, Schlichting E, Skretting G, Lie BA, Sandset PM, Iversen N (2014)
    Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
    BMC Cancer, 14, 845
    DOI 10.1186/1471-2407-14-845, PubMed 25407022
  40. Tramm T, Kyndi M, Myhre S, Nord S, Alsner J, Sørensen FB, Sørlie T, Overgaard J (2014)
    Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer
    Acta Oncol, 53 (10), 1337-46
    DOI 10.3109/0284186X.2014.925580, PubMed 24957550
  41. Tramm T, Mohammed H, Myhre S, Kyndi M, Alsner J, Børresen-Dale AL, Sørlie T, Frigessi A, Overgaard J (2014)
    Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort
    Clin Cancer Res, 20 (20), 5272-80
    DOI 10.1158/1078-0432.CCR-14-0458, PubMed 25149560
  42. Trinh A, Rye IH, Almendro V, Helland A, Russnes HG, Markowetz F (2014)
    GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images
    Genome Biol, 15 (8), 442
    DOI 10.1186/s13059-014-0442-y, PubMed 25168174
  43. Tubio JMC, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Marshall J, Wedge DC, Teague JW, Butler AP et al. (2014)
    Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
    Science, 345 (6196), 1251343
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  44. Vogel LK, Sæbø M, Høyer H, Kopp TI, Vogel U, Godiksen S, Frenzel FB, Hamfjord J, Bowitz-Lothe IM, Johnson E, Kure EH, Andersen V (2014)
    Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis
    PLoS One, 9 (8), e105254
    DOI 10.1371/journal.pone.0105254, PubMed 25166592
  45. Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN, METABRIC Group, Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C (2014)
    A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer
    Mol Oncol, 9 (1), 115-27
    DOI 10.1016/j.molonc.2014.07.019, PubMed 25169931
  46. Wennerström AB, Lothe IM, Sandhu V, Kure EH, Myklebost O, Munthe E (2014)
    Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines
    PLoS One, 9 (8), e103873
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  47. Winsel S, Mäki-Jouppila J, Tambe M, Aure MR, Pruikkonen S, Salmela AL, Halonen T, Leivonen SK, Kallio L, Børresen-Dale AL, Kallio MJ (2014)
    Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo
    Br J Cancer, 111 (11), 2142-51
    DOI 10.1038/bjc.2014.524, PubMed 25268374
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    JARID1B is a luminal lineage-driving oncogene in breast cancer
    Cancer Cell, 25 (6), 762-77
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  49. Zhao X, Rødland EA, Sørlie T, Vollan HK, Russnes HG, Kristensen VN, Lingjærde OC, Børresen-Dale AL (2014)
    Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
    BMC Cancer, 14, 211
    DOI 10.1186/1471-2407-14-211, PubMed 24645668

Publications 2013

  1. Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
    Signatures of mutational processes in human cancer
    Nature, 500 (7463), 415-21
    DOI 10.1038/nature12477, PubMed 23945592
  2. Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
    Low ABCB1 gene expression is an early event in colorectal carcinogenesis
    PLoS One, 8 (8), e72119
    DOI 10.1371/journal.pone.0072119, PubMed 23977225
  3. Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
    Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
    Genome Biol, 14 (11), R126
    DOI 10.1186/gb-2013-14-11-r126, PubMed 24257477
  4. Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
    Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
    PLoS One, 8 (1), e53014
    DOI 10.1371/journal.pone.0053014, PubMed 23382830
  5. Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
    High levels of genomic aberrations in serous ovarian cancers are associated with better survival
    PLoS One, 8 (1), e54356
    DOI 10.1371/journal.pone.0054356, PubMed 23372714
  6. Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
    Improving breast cancer survival analysis through competition-based multidimensional modeling
    PLoS Comput Biol, 9 (5), e1003047
    DOI 10.1371/journal.pcbi.1003047, PubMed 23671412
  7. Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
    Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
    Nat Genet, 45 (4), 371-84, 384e1-2
    DOI 10.1038/ng.2566, PubMed 23535731
  8. Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
    Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
    Cell Stem Cell, 13 (1), 117-30
    DOI 10.1016/j.stem.2013.05.004, PubMed 23770079
  9. Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
    SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
    Int J Radiat Oncol Biol Phys, 86 (4), 791-9
    DOI 10.1016/j.ijrobp.2013.02.025, PubMed 23597419
  10. Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
    Triple-negative breast cancer and the need for new therapeutic targets
    Am J Pathol, 183 (4), 1064-1074
    DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327
  11. French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
    Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
    Am J Hum Genet, 92 (4), 489-503
    DOI 10.1016/j.ajhg.2013.01.002, PubMed 23540573
  12. Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
    Genome-wide association studies identify four ER negative-specific breast cancer risk loci
    Nat Genet, 45 (4), 392-8, 398e1-2
    DOI 10.1038/ng.2561, PubMed 23535733
  13. Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
    Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
    Cancer Res, 73 (21), 6424-34
    DOI 10.1158/0008-5472.CAN-12-4573, PubMed 24030979
  14. Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
    Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
    PLoS One, 8 (11), e78241
    DOI 10.1371/journal.pone.0078241, PubMed 24244297
  15. Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
    High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
    PLoS One, 8 (10), e77232
    DOI 10.1371/journal.pone.0077232, PubMed 24194875
  16. Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
    AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
    Breast Cancer Res Treat, 141 (3), 397-408
    DOI 10.1007/s10549-013-2702-z, PubMed 24091768
  17. Katika MR, Hurtado A (2013)
    A functional link between FOXA1 and breast cancer SNPs
    Breast Cancer Res, 15 (1), 303
    DOI 10.1186/bcr3360, PubMed 23427833
  18. Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
    Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
    Mol Oncol, 8 (1), 59-67
    DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443
  19. Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
    Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
    BMC Cancer, 13, 456
    DOI 10.1186/1471-2407-13-456, PubMed 24093668
  20. Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
    Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
    Genomics, 102 (4), 278-87
    DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221
  21. Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
    High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
    Mol Oncol, 8 (1), 93-104
    DOI 10.1016/j.molonc.2013.10.001, PubMed 24148764
  22. Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
    Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
    J Med Genet, 50 (10), 666-73
    DOI 10.1136/jmedgenet-2013-101708, PubMed 23825393
  23. Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
    Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
    Clin Cancer Res, 20 (2), 404-12
    DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926
  24. Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
    Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
    Breast Cancer Res Treat, 143 (1), 189-201
    DOI 10.1007/s10549-013-2796-3, PubMed 24305980
  25. Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
    Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
    Sci Transl Med, 5 (181), 181re1
    DOI 10.1126/scitranslmed.3006112, PubMed 23596205
  26. Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
    Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
    Am J Hum Genet, 93 (6), 1046-60
    DOI 10.1016/j.ajhg.2013.10.026, PubMed 24290378
  27. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
    Large-scale genotyping identifies 41 new loci associated with breast cancer risk
    Nat Genet, 45 (4), 353-61, 361e1-2
    DOI 10.1038/ng.2563, PubMed 23535729
  28. Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
    A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
    Hum Mol Genet, 23 (7), 1934-46
    DOI 10.1093/hmg/ddt581, PubMed 24242184
  29. Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
    Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
    Mol Oncol, 7 (3), 704-18
    DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353
  30. Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
    Next-generation sequencing of disseminated tumor cells
    Front Oncol, 3, 320
    DOI 10.3389/fonc.2013.00320, PubMed 24427740
  31. Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
    Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
    Pancreatology, 13 (2), 180-5
    DOI 10.1016/j.pan.2013.01.003, PubMed 23561977
  32. Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
    Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
    PLoS One, 8 (5), e62153
    DOI 10.1371/journal.pone.0062153, PubMed 23671585
  33. Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
    Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
    Carcinogenesis, 35 (5), 1012-9
    DOI 10.1093/carcin/bgt404, PubMed 24325915
  34. Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
    The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
    Mol Oncol, 8 (2), 273-84
    DOI 10.1016/j.molonc.2013.11.008, PubMed 24388359
  35. Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
    Two Distinct Categories of Focal Deletions in Cancer Genomes
    PLoS One, 8 (6), e66264
    DOI 10.1371/journal.pone.0066264, PubMed 23805207
  36. Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
    Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
    ISRN Oncol, 2013, 924971
    DOI 10.1155/2013/924971, PubMed 23533813
  37. Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
    Clinical significance of disseminated tumour cells in non-small cell lung cancer
    Br J Cancer, 109 (5), 1264-70
    DOI 10.1038/bjc.2013.450, PubMed 23942067
  38. Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
    Osteopontin is a prognostic biomarker in non-small cell lung cancer
    BMC Cancer, 13, 540
    DOI 10.1186/1471-2407-13-540, PubMed 24215488
  39. Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
    Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
    Carcinogenesis, 35 (1), 76-85
    DOI 10.1093/carcin/bgt333, PubMed 24104550
  40. Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
    Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
    Virchows Arch, 463 (6), 775-86
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    Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
    BMC Cancer, 13, 512
    DOI 10.1186/1471-2407-13-512, PubMed 24171825
  42. Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
    Personalized cancer care conference
    J Pers Med, 3 (2), 70-81
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Publications 2012

  1. Bilal E, Vassallo K, Toppmeyer D, Barnard N, Rye IH, Almendro V, Russnes H, Børresen-Dale AL, Levine AJ, Bhanot G, Ganesan S (2012)
    Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers
    PLoS One, 7 (6), e38575
    DOI 10.1371/journal.pone.0038575, PubMed 22719901
  2. Borgan E, Lindholm EM, Moestue S, Mælandsmo GM, Lingjærde OC, Gribbestad IS, Børresen-Dale AL, Engebraaten O, Sørlie T (2012)
    Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
    Mol Oncol, 7 (1), 130-42
    DOI 10.1016/j.molonc.2012.10.005, PubMed 23142657
  3. Brustugun OT, Helland Å, Fjellbirkeland L, Kleinberg L, Ariansen S, Jebsen P, Scott H, Dønnem T, Bremnes R, Berg T, Grønberg BH, Dai HY, Wahl SG, Mangseth K, Helgeland L (2012)
    [Mutation testing for non-small-cell lung cancer]
    Tidsskr Nor Laegeforen, 132 (8), 952-5
    DOI 10.4045/tidsskr.11.1017, PubMed 22562326
  4. Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S, METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L et al. (2012)
    The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    Nature, 486 (7403), 346-52
    DOI 10.1038/nature10983, PubMed 22522925
  5. Engebraaten O, Edvardsen H, Løkkevik E, Naume B, Kristensen V, Ottestad L, Natarajan V (2012)
    Gefitinib in Combination with Weekly Docetaxel in Patients with Metastatic Breast Cancer Caused Unexpected Toxicity: Results from a Randomized Phase II Clinical Trial
    ISRN Oncol, 2012, 176789
    DOI 10.5402/2012/176789, PubMed 22666610
  6. Fiorito E, Katika MR, Hurtado A (2012)
    Cooperating transcription factors mediate the function of estrogen receptor
    Chromosoma, 122 (1-2), 1-12
    DOI 10.1007/s00412-012-0392-7, PubMed 23192763
  7. Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C (2012)
    Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
    Cell, 148 (1-2), 244-58
    DOI 10.1016/j.cell.2011.12.017, PubMed 22265415
  8. Ghoussaini M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang Q, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K, Johnson N, Orr N, dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Hall P, Czene K et al. (2012)
    Genome-wide association analysis identifies three new breast cancer susceptibility loci
    Nat Genet, 44 (3), 312-8
    DOI 10.1038/ng.1049, PubMed 22267197
  9. Gilfillan S, Fiorito E, Hurtado A (2012)
    Functional genomic methods to study estrogen receptor activity
    J Mammary Gland Biol Neoplasia, 17 (2), 147-53
    DOI 10.1007/s10911-012-9254-4, PubMed 22588661
  10. Guiu S, Michiels S, André F, Cortes J, Denkert C, Di Leo A, Hennessy BT, Sorlie T, Sotiriou C, Turner N, Van de Vijver M, Viale G, Loi S, Reis-Filho JS (2012)
    Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement
    Ann Oncol, 23 (12), 2997-3006
    DOI 10.1093/annonc/mds586, PubMed 23166150
  11. Hamfjord J, Stangeland AM, Hughes T, Skrede ML, Tveit KM, Ikdahl T, Kure EH (2012)
    Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing
    PLoS One, 7 (4), e34150
    DOI 10.1371/journal.pone.0034150, PubMed 22529906
  12. Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A, Hogervorst FB, Bueno-de-Mesquita HB, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Fasching PA, Hein A, Ekici AB, Beckmann MW, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Sawyer E, Tomlinson I, Kerin M et al. (2012)
    Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)
    PLoS One, 7 (8), e42380
    DOI 10.1371/journal.pone.0042380, PubMed 22879957
  13. Joshi H, Bhanot G, Børresen-Dale AL, Kristensen V (2012)
    Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway
    Br J Cancer, 107 (10), 1722-8
    DOI 10.1038/bjc.2012.461, PubMed 23079576
  14. Joshi H, Nord SH, Frigessi A, Børresen-Dale AL, Kristensen VN (2012)
    Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
    BMC Genomics, 13, 199
    DOI 10.1186/1471-2164-13-199, PubMed 22616941
  15. Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW (2012)
    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
    Proc Natl Acad Sci U S A, 109 (16), 6124-9
    DOI 10.1073/pnas.1203203109, PubMed 22454501
  16. Kjersem JB, Ikdahl T, Guren T, Skovlund E, Sorbye H, Hamfjord J, Pfeiffer P, Glimelius B, Kersten C, Solvang H, Tveit KM, Kure EH (2012)
    Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab
    BMC Cancer, 12, 534
    DOI 10.1186/1471-2407-12-534, PubMed 23167843
  17. Kure EH, Hamfjord J, Stangeland AM, Tveit KM, Ikdahl T (2012)
    KRAS mutational test for metastatic colorectal cancer patients: not just a technical problem
    Expert Rev Mol Diagn, 12 (4), 327-8
    DOI 10.1586/erm.12.29, PubMed 22616697
  18. Lambrechts D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, Apicella C, Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien R, Sawyer E, Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez JI, Benítez J, Hamann U, Ko YD, Brüning T, GENICA Network et al. (2012)
    11q13 is a susceptibility locus for hormone receptor positive breast cancer
    Hum Mutat, 33 (7), 1123-32
    DOI 10.1002/humu.22089, PubMed 22461340
  19. Mathiesen RR, Borgen E, Renolen A, Løkkevik E, Nesland JM, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Kvalheim G, Lønning PE, Naume B (2012)
    Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
    Breast Cancer Res, 14 (4), R117
    DOI 10.1186/bcr3242, PubMed 22889108
  20. Natrajan R, Mackay A, Wilkerson PM, Lambros MB, Wetterskog D, Arnedos M, Shiu KK, Geyer FC, Langerød A, Kreike B, Reyal F, Horlings HM, van de Vijver MJ, Palacios J, Weigelt B, Reis-Filho JS (2012)
    Functional characterization of the 19q12 amplicon in grade III breast cancers
    Breast Cancer Res, 14 (2), R53
    DOI 10.1186/bcr3154, PubMed 22433433
  21. Nik-Zainal S, Alexandrov LB, Wedge DC, Van Loo P, Greenman CD, Raine K, Jones D, Hinton J, Marshall J, Stebbings LA, Menzies A, Martin S, Leung K, Chen L, Leroy C, Ramakrishna M, Rance R, Lau KW, Mudie LJ, Varela I, McBride DJ, Bignell GR, Cooke SL, Shlien A, Gamble J et al. (2012)
    Mutational processes molding the genomes of 21 breast cancers
    Cell, 149 (5), 979-93
    DOI 10.1016/j.cell.2012.04.024, PubMed 22608084
  22. Nik-Zainal S, Van Loo P, Wedge DC, Alexandrov LB, Greenman CD, Lau KW, Raine K, Jones D, Marshall J, Ramakrishna M, Shlien A, Cooke SL, Hinton J, Menzies A, Stebbings LA, Leroy C, Jia M, Rance R, Mudie LJ, Gamble SJ, Stephens PJ, McLaren S, Tarpey PS, Papaemmanuil E, Davies HR et al. (2012)
    The life history of 21 breast cancers
    Cell, 149 (5), 994-1007
    DOI 10.1016/j.cell.2012.04.023, PubMed 22608083
  23. Nilsen G, Liestøl K, Van Loo P, Moen Vollan HK, Eide MB, Rueda OM, Chin SF, Russell R, Baumbusch LO, Caldas C, Børresen-Dale AL, Lingjaerde OC (2012)
    Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
    BMC Genomics, 13, 591
    DOI 10.1186/1471-2164-13-591, PubMed 23442169
  24. Otto B, Gruner K, Heinlein C, Wegwitz F, Nollau P, Ylstra B, Pantel K, Schumacher U, Baumbusch LO, Martin-Subero JI, Siebert R, Wagener C, Streichert T, Deppert W, Tolstonog GV (2012)
    Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression
    Int J Cancer, 132 (6), 1300-10
    DOI 10.1002/ijc.27783, PubMed 22907219
  25. Ree AH, Kristensen AT, Saelen MG, de Wijn R, Edvardsen H, Jovanovic J, Abrahamsen TW, Dueland S, Flatmark K (2012)
    Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer
    PLoS One, 7 (11), e50806
    DOI 10.1371/journal.pone.0050806, PubMed 23226389
  26. Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR (2012)
    Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes
    ISRN Oncol, 2012, 450267
    DOI 10.5402/2012/450267, PubMed 23227362
  27. Sagerup CM, Småstuen M, Johannesen TB, Helland A, Brustugun OT (2012)
    Increasing age and carcinoma not otherwise specified: a 20-year population study of 40,118 lung cancer patients
    J Thorac Oncol, 7 (1), 57-63
    DOI 10.1097/JTO.0b013e3182307f7e, PubMed 21900838
  28. Sahlberg KK, Hongisto V, Edgren H, Mäkelä R, Hellström K, Due EU, Moen Vollan HK, Sahlberg N, Wolf M, Børresen-Dale AL, Perälä M, Kallioniemi O (2012)
    The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells
    Mol Oncol, 7 (3), 392-401
    DOI 10.1016/j.molonc.2012.10.012, PubMed 23253899
  29. Stavnes HT, Nymoen DA, Langerød A, Holth A, Børresen Dale AL, Davidson B (2012)
    AZGP1 and SPDEF mRNA expression differentiates breast carcinoma from ovarian serous carcinoma
    Virchows Arch, 462 (2), 163-73
    DOI 10.1007/s00428-012-1347-3, PubMed 23242172
  30. Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A et al. (2012)
    The landscape of cancer genes and mutational processes in breast cancer
    Nature, 486 (7403), 400-4
    DOI 10.1038/nature11017, PubMed 22722201
  31. Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, Nickels S, Brauch H, GENICA Network, Ko YD, Fischer HP, Schmutzler RK, Meindl A, Bartram CR, Schott S, Engel C et al. (2012)
    19p13.1 is a triple-negative-specific breast cancer susceptibility locus
    Cancer Res, 72 (7), 1795-803
    DOI 10.1158/0008-5472.CAN-11-3364, PubMed 22331459
  32. Synnestvedt M, Borgen E, Russnes HG, Kumar NT, Schlichting E, Giercksky KE, Kåresen R, Nesland JM, Naume B (2012)
    Combined analysis of vascular invasion, grade, HER2 and Ki67 expression identifies early breast cancer patients with questionable benefit of systemic adjuvant therapy
    Acta Oncol, 52 (1), 91-101
    DOI 10.3109/0284186X.2012.713508, PubMed 22934555
  33. Tveit KM, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, Sigurdsson F, Kure E, Ikdahl T, Skovlund E, Fokstuen T, Hansen F, Hofsli E, Birkemeyer E, Johnsson A, Starkhammar H, Yilmaz MK, Keldsen N, Erdal AB, Dajani O, Dahl O, Christoffersen T (2012)
    Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDIC-VII study
    J Clin Oncol, 30 (15), 1755-62
    DOI 10.1200/JCO.2011.38.0915, PubMed 22473155
  34. Vachon CM, Scott CG, Fasching PA, Hall P, Tamimi RM, Li J, Stone J, Apicella C, Odefrey F, Gierach GL, Jud SM, Heusinger K, Beckmann MW, Pollan M, Fernández-Navarro P, Gonzalez-Neira A, Benitez J, van Gils CH, Lokate M, Onland-Moret NC, Peeters PH, Brown J, Leyland J, Varghese JS, Easton DF et al. (2012)
    Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk
    Cancer Epidemiol Biomarkers Prev, 21 (7), 1156-66
    DOI 10.1158/1055-9965.EPI-12-0066, PubMed 22454379
  35. Vaclavikova R, Ehrlichova M, Hlavata I, Pecha V, Kozevnikovova R, Trnkova M, Adamek J, Edvardsen H, Kristensen VN, Gut I, Soucek P (2012)
    Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis
    Clin Chem Lab Med, 50 (11), 1999-2007
    DOI 10.1515/cclm-2012-0103, PubMed 23093106
  36. Van Loo P, Nilsen G, Nordgard SH, Vollan HK, Børresen-Dale AL, Kristensen VN, Lingjærde OC (2012)
    Analyzing cancer samples with SNP arrays
    Methods Mol Biol, 802, 57-72
    DOI 10.1007/978-1-61779-400-1_4, PubMed 22130873
  37. Weischer M, Nordestgaard BG, Pharoah P, Bolla MK, Nevanlinna H, Van't Veer LJ, Garcia-Closas M, Hopper JL, Hall P, Andrulis IL, Devilee P, Fasching PA, Anton-Culver H, Lambrechts D, Hooning M, Cox A, Giles GG, Burwinkel B, Lindblom A, Couch FJ, Mannermaa A, Grenaker Alnæs G, John EM, Dörk T, Flyger H et al. (2012)
    CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer
    J Clin Oncol, 30 (35), 4308-16
    DOI 10.1200/JCO.2012.42.7336, PubMed 23109706

Publications 2011

  1. Berner A, Lund-Iversen M, Nesland JM (2011)
    Fine needle aspirations in oncology
    Arkh Patol, 73 (4), 21-6
    PubMed 22164426
  2. Borgan E, Navon R, Vollan HK, Schlichting E, Sauer T, Yakhini Z, Lingjærde OC, Sørlie T, Børresen-Dale AL (2011)
    Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue
    Mol Oncol, 5 (6), 564-76
    DOI 10.1016/j.molonc.2011.08.004, PubMed 21917534
  3. Borge KS, Børresen-Dale AL, Lingaas F (2011)
    Identification of genetic variation in 11 candidate genes of canine mammary tumour
    Vet Comp Oncol, 9 (4), 241-50
    DOI 10.1111/j.1476-5829.2010.00250.x, PubMed 22077404
  4. Bornholdt J, Friis S, Godiksen S, Poulsen SS, Santoni-Rugiu E, Bisgaard HC, Lothe IM, Ikdahl T, Tveit KM, Johnson E, Kure EH, Vogel LK (2011)
    The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
    BMC Cancer, 11, 65
    DOI 10.1186/1471-2407-11-65, PubMed 21310043
  5. Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, Apicella C, Smith LD, Hammet F, Southey MC, Van 't Veer LJ, de Groot R, Smit VT, Fasching PA, Beckmann MW, Jud S, Ekici AB, Hartmann A, Hein A, Schulz-Wendtland R, Burwinkel B, Marme F, Schneeweiss A, Sinn HP, Sohn C et al. (2011)
    Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
    Hum Mol Genet, 20 (16), 3289-303
    DOI 10.1093/hmg/ddr228, PubMed 21596841
  6. Edgren H, Murumagi A, Kangaspeska S, Nicorici D, Hongisto V, Kleivi K, Rye IH, Nyberg S, Wolf M, Borresen-Dale AL, Kallioniemi O (2011)
    Identification of fusion genes in breast cancer by paired-end RNA-sequencing
    Genome Biol, 12 (1), R6
    DOI 10.1186/gb-2011-12-1-r6, PubMed 21247443
  7. Enerly E, Steinfeld I, Kleivi K, Leivonen SK, Aure MR, Russnes HG, Rønneberg JA, Johnsen H, Navon R, Rødland E, Mäkelä R, Naume B, Perälä M, Kallioniemi O, Kristensen VN, Yakhini Z, Børresen-Dale AL (2011)
    miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
    PLoS One, 6 (2), e16915
    DOI 10.1371/journal.pone.0016915, PubMed 21364938
  8. Gonzalez-Angulo AM, Hennessy BT, Meric-Bernstam F, Sahin A, Liu W, Ju Z, Carey MS, Myhre S, Speers C, Deng L, Broaddus R, Lluch A, Aparicio S, Brown P, Pusztai L, Symmans WF, Alsner J, Overgaard J, Borresen-Dale AL, Hortobagyi GN, Coombes KR, Mills GB (2011)
    Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer
    Clin Proteomics, 8 (1), 11
    DOI 10.1186/1559-0275-8-11, PubMed 21906370
  9. Grinde MT, Moestue SA, Borgan E, Risa Ø, Engebraaten O, Gribbestad IS (2011)
    13C high-resolution-magic angle spinning MRS reveals differences in glucose metabolism between two breast cancer xenograft models with different gene expression patterns
    NMR Biomed, 24 (10), 1243-52
    DOI 10.1002/nbm.1683, PubMed 21462378
  10. Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, Lawrence MS, Onofrio RC, Salvesen HB, Seidel D, Zander T, Heuckmann JM, Soltermann A, Moch H, Koker M, Leenders F et al. (2011)
    Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
    Cancer Discov, 1 (1), 78-89
    DOI 10.1158/2159-8274.CD-11-0005, PubMed 22328973
  11. Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, Australian Ovarian Cancer Study Group, Pearson RB, Børresen-Dale AL, Huntsman DG, deFazio A, Creighton CJ, Smyth GK, Bowtell DD (2011)
    Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
    PLoS One, 6 (4), e18064
    DOI 10.1371/journal.pone.0018064, PubMed 21533284
  12. Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT (2011)
    EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
    J Thorac Oncol, 6 (5), 947-50
    DOI 10.1097/JTO.0b013e31820db209, PubMed 21623266
  13. Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY (2011)
    Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
    Nat Genet, 43 (7), 621-9
    DOI 10.1038/ng.848, PubMed 21642992
  14. Haakensen VD, Bjøro T, Lüders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Børresen-Dale AL, Helland Å (2011)
    Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
    BMC Cancer, 11, 332
    DOI 10.1186/1471-2407-11-332, PubMed 21812955
  15. Haakensen VD, Lingjaerde OC, Lüders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Børresen-Dale AL, Helland A (2011)
    Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
    BMC Med Genomics, 4, 77
    DOI 10.1186/1755-8794-4-77, PubMed 22044755
  16. Kaveh F, Edvardsen H, Børresen-Dale AL, N Kristensen V, Solvang HK (2011)
    Allele-specific disparity in breast cancer
    BMC Med Genomics, 4, 85
    DOI 10.1186/1755-8794-4-85, PubMed 22188678
  17. Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS et al. (2011)
    The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
    Cancer Cell, 19 (2), 273-82
    DOI 10.1016/j.ccr.2010.12.019, PubMed 21316605
  18. Kristensen VN (2011)
    Divide and conquer: the genetic basis of molecular subclassification of breast cancer
    EMBO Mol Med, 3 (4), 183-5
    DOI 10.1002/emmm.201100128, PubMed 21394915
  19. Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland Å, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL (2011)
    Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
    Proc Natl Acad Sci U S A, 109 (8), 2802-7
    DOI 10.1073/pnas.1108781108, PubMed 21908711
  20. Lund-Iversen M (2011)
    [Tumor diagnosis]
    Tidsskr Nor Laegeforen, 131 (1), 32
    DOI 10.4045/tidsskr.10.0996, PubMed 21233885
  21. Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA (2011)
    ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
    Front Biosci (Elite Ed), 3, 1443-55
    PubMed 21622148
  22. Mathiesen RR, Fjelldal R, Liestøl K, Due EU, Geigl JB, Riethdorf S, Borgen E, Rye IH, Schneider IJ, Obenauf AC, Mauermann O, Nilsen G, Christian Lingjaerde O, Børresen-Dale AL, Pantel K, Speicher MR, Naume B, Baumbusch LO (2011)
    High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer
    Int J Cancer, 131 (4), E405-15
    DOI 10.1002/ijc.26444, PubMed 21935921
  23. Milne RL, Goode EL, García-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N, Zamora MP, Arias Pérez JI, Benítez J, Dörk T, Schürmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliot G, Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC et al. (2011)
    Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
    Cancer Epidemiol Biomarkers Prev, 20 (10), 2222-31
    DOI 10.1158/1055-9965.EPI-11-0569, PubMed 21795498
  24. Molloy TJ, Bosma AJ, Baumbusch LO, Synnestvedt M, Borgen E, Russnes HG, Schlichting E, van't Veer LJ, Naume B (2011)
    The prognostic significance of tumour cell detection in the peripheral blood versus the bone marrow in 733 early-stage breast cancer patients
    Breast Cancer Res, 13 (3), R61
    DOI 10.1186/bcr2898, PubMed 21672237
  25. Møller P, Clark N, Mæhle L (2011)
    A SImplified method for Segregation Analysis (SISA) to determine penetrance and expression of a genetic variant in a family
    Hum Mutat, 32 (5), 568-71
    DOI 10.1002/humu.21441, PubMed 21309035
  26. Perou CM, Børresen-Dale AL (2011)
    Systems biology and genomics of breast cancer
    Cold Spring Harb Perspect Biol, 3 (2)
    DOI 10.1101/cshperspect.a003293, PubMed 21047916
  27. Reinertsen KV, Grenaker Alnæs GI, Landmark-Høyvik H, Loge JH, Wist E, Kristensen VN, Fosså SD, Edvardsen H (2011)
    Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway
    Brain Behav Immun, 25 (7), 1376-83
    DOI 10.1016/j.bbi.2011.04.001, PubMed 21496483
  28. Russnes HG, Kuligina ESh, Suspitsin EN, Voskresenskiy DA, Jordanova ES, Cornelisse CJ, Borresen-Dale AL, Imyanitov EN (2011)
    Paired distribution of molecular subtypes in bilateral breast carcinomas
    Cancer Genet, 204 (2), 96-102
    DOI 10.1016/j.cancergencyto.2010.09.012, PubMed 21504707
  29. Russnes HG, Navin N, Hicks J, Borresen-Dale AL (2011)
    Insight into the heterogeneity of breast cancer through next-generation sequencing
    J Clin Invest, 121 (10), 3810-8
    DOI 10.1172/JCI57088, PubMed 21965338
  30. Solvang HK, Lingjærde OC, Frigessi A, Børresen-Dale AL, Kristensen VN (2011)
    Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
    BMC Bioinformatics, 12, 197
    DOI 10.1186/1471-2105-12-197, PubMed 21609452
  31. Sørlie T (2011)
    How to personalise treatment in early breast cancer
    Eur J Cancer, 47 Suppl 3, S310-1
    DOI 10.1016/S0959-8049(11)70182-4, PubMed 21943994
  32. Turzer M, Brustugun OT, Waldeland E, Helland A (2011)
    Stereotactic body radiation therapy is effective and safe in patients with early-stage non-small cell lung cancer with low performance status and severe comorbidity
    Case Rep Oncol, 4 (1), 25-34
    DOI 10.1159/000324113, PubMed 21526003
  33. van den Broek AJ, Broeks A, Horlings HM, Canisius SV, Braaf LM, Langerød A, Van't Veer LJ, Schmidt MK (2011)
    Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups
    Breast Cancer Res Treat, 130 (2), 599-608
    DOI 10.1007/s10549-011-1615-y, PubMed 21667122
  34. Vollan HK, Caldas C (2011)
    The breast cancer genome--a key for better oncology
    BMC Cancer, 11, 501
    DOI 10.1186/1471-2407-11-501, PubMed 22128823
  35. Weigman VJ, Chao HH, Shabalin AA, He X, Parker JS, Nordgard SH, Grushko T, Huo D, Nwachukwu C, Nobel A, Kristensen VN, Børresen-Dale AL, Olopade OI, Perou CM (2011)
    Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
    Breast Cancer Res Treat, 133 (3), 865-80
    DOI 10.1007/s10549-011-1846-y, PubMed 22048815
  36. Westbury CB, Sahlberg KK, Borresen-Dale AL, Isacke CM, Yarnold JR (2011)
    Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients
    Radiat Oncol, 6, 42
    DOI 10.1186/1748-717X-6-42, PubMed 21521514
  37. Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
    Combining gene signatures improves prediction of breast cancer survival
    PLoS One, 6 (3), e17845
    DOI 10.1371/journal.pone.0017845, PubMed 21423775

Publications 2010

  1. Anaganti S, Fernández-Cuesta L, Langerød A, Hainaut P, Olivier M (2010)
    p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines
    Cancer Lett, 300 (2), 215-24
    DOI 10.1016/j.canlet.2010.10.008, PubMed 21071137
  2. Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, Blandino G, Børresen-Dale AL, Pilpel Y, Yakhini Z, Segal E, Yarden Y (2010)
    EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors
    Sci Signal, 3 (124), ra43
    DOI 10.1126/scisignal.2000876, PubMed 20516477
  3. Berge EO, Knappskog S, Geisler S, Staalesen V, Pacal M, Børresen-Dale AL, Puntervoll P, Lillehaug JR, Lønning PE (2010)
    Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
    Mol Cancer, 9, 173
    DOI 10.1186/1476-4598-9-173, PubMed 20594292
  4. Bernstein JL, Haile RW, Stovall M, Boice JD, Shore RE, Langholz B, Thomas DC, Bernstein L, Lynch CF, Olsen JH, Malone KE, Mellemkjaer L, Borresen-Dale AL, Rosenstein BS, Teraoka SN, Diep AT, Smith SA, Capanu M, Reiner AS, Liang X, Gatti RA, Concannon P, WECARE Study Collaborative Group (2010)
    Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study
    J Natl Cancer Inst, 102 (7), 475-83
    DOI 10.1093/jnci/djq055, PubMed 20305132
  5. Biong M, Gram IT, Brill I, Johansen F, Solvang HK, Alnaes GI, Fagerheim T, Bremnes Y, Chanock SJ, Burdett L, Yeager M, Ursin G, Kristensen VN (2010)
    Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density
    BMC Med Genomics, 3, 9
    DOI 10.1186/1755-8794-3-9, PubMed 20302654
  6. Borg A, Haile RW, Malone KE, Capanu M, Diep A, Törngren T, Teraoka S, Begg CB, Thomas DC, Concannon P, Mellemkjaer L, Bernstein L, Tellhed L, Xue S, Olson ER, Liang X, Dolle J, Børresen-Dale AL, Bernstein JL (2010)
    Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study
    Hum Mutat, 31 (3), E1200-40
    DOI 10.1002/humu.21202, PubMed 20104584
  7. Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, Sørlie T, Børresen-Dale AL, Gribbestad IS (2010)
    Merging transcriptomics and metabolomics--advances in breast cancer profiling
    BMC Cancer, 10, 628
    DOI 10.1186/1471-2407-10-628, PubMed 21080935
  8. Borresen-Dale AL (2010)
    Europe's largest Member Association for Cancer Research
    Period. Biol., 112 (4), 483-485
  9. Børresen-Dale AL, Sørlie T, Kristensen VN (2010)
    On the molecular biology of breast cancer
    Mol Oncol, 4 (3), 171-3
    DOI 10.1016/j.molonc.2010.04.007, PubMed 20483673
  10. de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L (2010)
    Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
    Am J Pathol, 176 (3), 1229-40
    DOI 10.2353/ajpath.2010.090648, PubMed 20133812
  11. Dejeux E, Rønneberg JA, Solvang H, Bukholm I, Geisler S, Aas T, Gut IG, Børresen-Dale AL, Lønning PE, Kristensen VN, Tost J (2010)
    DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
    Mol Cancer, 9, 68
    DOI 10.1186/1476-4598-9-68, PubMed 20338046
  12. Dossus L, Allen N, Kaaks R, Bakken K, Lund E, Tjonneland A, Olsen A, Overvad K, Clavel-Chapelon F, Fournier A, Chabbert-Buffet N, Boeing H, Schütze M, Trichopoulou A, Trichopoulos D, Lagiou P, Palli D, Krogh V, Tumino R, Vineis P, Mattiello A, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Dumeaux V et al. (2010)
    Reproductive risk factors and endometrial cancer: the European Prospective Investigation into Cancer and Nutrition
    Int J Cancer, 127 (2), 442-51
    DOI 10.1002/ijc.25050, PubMed 19924816
  13. Dumeaux V, Olsen KS, Nuel G, Paulssen RH, Børresen-Dale AL, Lund E (2010)
    Deciphering normal blood gene expression variation--The NOWAC postgenome study
    PLoS Genet, 6 (3), e1000873
    DOI 10.1371/journal.pgen.1000873, PubMed 20300640
  14. Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
    SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
    Pharmacogenomics J, 10 (6), 513-23
    DOI 10.1038/tpj.2010.6, PubMed 20157331
  15. Fu YP, Edvardsen H, Kaushiva A, Arhancet JP, Howe TM, Kohaar I, Porter-Gill P, Shah A, Landmark-Høyvik H, Fosså SD, Ambs S, Naume B, Børresen-Dale AL, Kristensen VN, Prokunina-Olsson L (2010)
    NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
    Mol Cancer, 9, 113
    DOI 10.1186/1476-4598-9-113, PubMed 20482849
  16. Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, Bedrosian I, McGahren M, Agarwal R, Zhang F, Overgaard J, Alsner J, Neve RM, Kuo WL, Gray JW, Borresen-Dale AL, Mills GB (2010)
    A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers
    Clin Proteomics, 6 (4), 129-51
    DOI 10.1007/s12014-010-9055-y, PubMed 21691416
  17. Holmøy T, Wilson JA, von der Lippe C, Andersen PM, Berg-Hansen P (2010)
    G127R: A novel SOD1 mutation associated with rapidly evolving ALS and severe pain syndrome
    Amyotroph Lateral Scler, 11 (5), 478-80
    DOI 10.3109/17482960903580315, PubMed 20192886
  18. Holstege H, Horlings HM, Velds A, Langerød A, Børresen-Dale AL, van de Vijver MJ, Nederlof PM, Jonkers J (2010)
    BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations
    BMC Cancer, 10, 654
    DOI 10.1186/1471-2407-10-654, PubMed 21118481
  19. Haakensen VD, Biong M, Lingjærde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Lüders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Børresen-Dale AL, Helland A (2010)
    Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
    Breast Cancer Res, 12 (4), R65
    DOI 10.1186/bcr2632, PubMed 20799965
  20. International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J et al. (2010)
    International network of cancer genome projects
    Nature, 464 (7291), 993-8
    DOI 10.1038/nature08987, PubMed 20393554
  21. Jovanovic J, Rønneberg JA, Tost J, Kristensen V (2010)
    The epigenetics of breast cancer
    Mol Oncol, 4 (3), 242-54
    DOI 10.1016/j.molonc.2010.04.002, PubMed 20627830
  22. Kamalakaran S, Varadan V, Giercksky Russnes HE, Levy D, Kendall J, Janevski A, Riggs M, Banerjee N, Synnestvedt M, Schlichting E, Kåresen R, Shama Prasada K, Rotti H, Rao R, Rao L, Eric Tang MH, Satyamoorthy K, Lucito R, Wigler M, Dimitrova N, Naume B, Borresen-Dale AL, Hicks JB (2010)
    DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
    Mol Oncol, 5 (1), 77-92
    DOI 10.1016/j.molonc.2010.11.002, PubMed 21169070
  23. Kristensen V, Borresen-Dale AL (2010)
    Mutations for the people
    EMBO Mol Med, 2 (5), 143-5
    DOI 10.1002/emmm.201000071, PubMed 20461736
  24. Landmark-Høyvik H, Dumeaux V, Reinertsen KV, Edvardsen H, Fosså SD, Børresen-Dale AL (2010)
    Blood gene expression profiling of breast cancer survivors experiencing fibrosis
    Int J Radiat Oncol Biol Phys, 79 (3), 875-83
    DOI 10.1016/j.ijrobp.2010.09.052, PubMed 21129856
  25. Landmark-Høyvik H, Reinertsen KV, Loge JH, Kristensen VN, Dumeaux V, Fosså SD, Børresen-Dale AL, Edvardsen H (2010)
    The genetics and epigenetics of fatigue
    PM R, 2 (5), 456-65
    DOI 10.1016/j.pmrj.2010.04.003, PubMed 20656628
  26. Marienhagen K, Helland A, Nordberg T, Guren MG, Hofsli E (2010)
    [How do Norwegian oncologists perceive their working conditions?]
    Tidsskr Nor Laegeforen, 130 (5), 487-9
    DOI 10.4045/tidsskr.08.0305, PubMed 20224615
  27. Moestue SA, Borgan E, Huuse EM, Lindholm EM, Sitter B, Børresen-Dale AL, Engebraaten O, Maelandsmo GM, Gribbestad IS (2010)
    Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models
    BMC Cancer, 10, 433
    DOI 10.1186/1471-2407-10-433, PubMed 20716336
  28. Muggerud AA, Hallett M, Johnsen H, Kleivi K, Zhou W, Tahmasebpoor S, Amini RM, Botling J, Børresen-Dale AL, Sørlie T, Wärnberg F (2010)
    Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
    Mol Oncol, 4 (4), 357-68
    DOI 10.1016/j.molonc.2010.06.007, PubMed 20663721
  29. Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J (2010)
    Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
    Breast Cancer Res, 12 (1), R3
    DOI 10.1186/bcr2466, PubMed 20056007
  30. Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T (2010)
    In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
    PLoS One, 5 (11), e14002
    DOI 10.1371/journal.pone.0014002, PubMed 21124964
  31. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
    Mol. Oncol., 4 (2), 169
  32. Papp J, Kovacs ME, Solyom S, Kasler M, Børresen-Dale AL, Olah E (2010)
    High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients
    BMC Med Genet, 11, 169
    DOI 10.1186/1471-2350-11-169, PubMed 21118512
  33. Pedersen RS, Brasch-Andersen C, Sim SC, Bergmann TK, Halling J, Petersen MS, Weihe P, Edvardsen H, Kristensen VN, Brøsen K, Ingelman-Sundberg M (2010)
    Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations
    Eur J Clin Pharmacol, 66 (12), 1199-205
    DOI 10.1007/s00228-010-0864-8, PubMed 20665013
  34. Peng J, Zhu J, Bergamaschi A, Han W, Noh DY, Pollack JR, Wang P (2010)
    Regularized Multivariate Regression for Identifying Master Predictors with Application to Integrative Genomics Study of Breast Cancer
    Ann Appl Stat, 4 (1), 53-77
    DOI 10.1214/09-AOAS271SUPP, PubMed 24489618
  35. Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sørlie T, Tagliabue E, Børresen-Dale AL, FEMME Consortium (2010)
    Triple-negative breast cancer: present challenges and new perspectives
    Mol Oncol, 4 (3), 209-29
    DOI 10.1016/j.molonc.2010.04.006, PubMed 20537966
  36. Rantala JK, Edgren H, Lehtinen L, Wolf M, Kleivi K, Vollan HK, Aaltola AR, Laasola P, Kilpinen S, Saviranta P, Iljin K, Kallioniemi O (2010)
    Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2
    Neoplasia, 12 (11), 877-88
    DOI 10.1593/neo.10548, PubMed 21082043
  37. Rebillard A, Jouan-Lanhouet S, Jouan E, Legembre P, Pizon M, Sergent O, Gilot D, Tekpli X, Lagadic-Gossmann D, Dimanche-Boitrel MT (2010)
    Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells
    Eur J Cancer, 46 (8), 1445-55
    DOI 10.1016/j.ejca.2010.01.034, PubMed 20202822
  38. Reinertsen KV, Cvancarova M, Loge JH, Edvardsen H, Wist E, Fosså SD (2010)
    Predictors and course of chronic fatigue in long-term breast cancer survivors
    J Cancer Surviv, 4 (4), 405-14
    DOI 10.1007/s11764-010-0145-7, PubMed 20862614
  39. Russnes HG, Vollan HKM, Lingjærde OC, Krasnitz A, Lundin P, Naume B, Sørlie T, Borgen E, Rye IH, Langerød A, Chin SF, Teschendorff AE, Stephens PJ, Månér S, Schlichting E, Baumbusch LO, Kåresen R, Stratton MP, Wigler M, Caldas C, Zetterberg A, Hicks J, Børresen-Dale AL (2010)
    Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
    Sci Transl Med, 2 (38), 38ra47
    DOI 10.1126/scitranslmed.3000611, PubMed 20592421
  40. Rønneberg JA, Fleischer T, Solvang HK, Nordgard SH, Edvardsen H, Potapenko I, Nebdal D, Daviaud C, Gut I, Bukholm I, Naume B, Børresen-Dale AL, Tost J, Kristensen V (2010)
    Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
    Mol Oncol, 5 (1), 61-76
    DOI 10.1016/j.molonc.2010.11.004, PubMed 21212030
  41. Sørlie T, Borgan E, Myhre S, Vollan HK, Russnes H, Zhao X, Nilsen G, Lingjaerde OC, Børresen-Dale AL, Rødland E (2010)
    The importance of gene-centring microarray data
    Lancet Oncol, 11 (8), 719-20; author reply 720-1
    DOI 10.1016/S1470-2045(10)70174-1, PubMed 20688275
  42. Turzer M, Brustugun OT, Helland A (2010)
    Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses
    Case Rep Oncol, 3 (2), 195-201
    DOI 10.1159/000317104, PubMed 20740196
  43. Van Loo P, Nordgard SH, Lingjærde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Børresen-Dale AL, Kristensen VN (2010)
    Allele-specific copy number analysis of tumors
    Proc Natl Acad Sci U S A, 107 (39), 16910-5
    DOI 10.1073/pnas.1009843107, PubMed 20837533
  44. Aarøe J, Lindahl T, Dumeaux V, Saebø S, Tobin D, Hagen N, Skaane P, Lönneborg A, Sharma P, Børresen-Dale AL (2010)
    Gene expression profiling of peripheral blood cells for early detection of breast cancer
    Breast Cancer Res, 12 (1), R7
    DOI 10.1186/bcr2472, PubMed 20078854

Publications 2009

  1. Agarwal R, Gonzalez-Angulo AM, Myhre S, Carey M, Lee JS, Overgaard J, Alsner J, Stemke-Hale K, Lluch A, Neve RM, Kuo WL, Sorlie T, Sahin A, Valero V, Keyomarsi K, Gray JW, Borresen-Dale AL, Mills GB, Hennessy BT (2009)
    Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
    Clin Cancer Res, 15 (11), 3654-62
    DOI 10.1158/1078-0432.CCR-08-3293, PubMed 19470724
  2. Andersen V, Agerstjerne L, Jensen D, Østergaard M, Saebø M, Hamfjord J, Kure E, Vogel U (2009)
    The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study
    BMC Med Genet, 10, 18
    DOI 10.1186/1471-2350-10-18, PubMed 19250544
  3. Beauchamp E, Tekpli X, Marteil G, Lagadic-Gossmann D, Legrand P, Rioux V (2009)
    N-Myristoylation targets dihydroceramide Delta4-desaturase 1 to mitochondria: partial involvement in the apoptotic effect of myristic acid
    Biochimie, 91 (11-12), 1411-9
    DOI 10.1016/j.biochi.2009.07.014, PubMed 19647031
  4. Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
    Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
    Mol Oncol, 3 (5-6), 469-82
    DOI 10.1016/j.molonc.2009.07.003, PubMed 19713161
  5. Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerød A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Børresen-Dale AL, Pollack JR (2009)
    Focal amplification and oncogene dependency of GAB2 in breast cancer
    Oncogene, 29 (5), 774-9
    DOI 10.1038/onc.2009.364, PubMed 19881546
  6. Dunning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodríguez R, Barbosa-Morais NL, Ponder BA, SEARCH, Low YL, Bingham S, EPIC, Haiman CA, Le Marchand L, MEC, Broeks A, Schmidt MK, ABCS, Hopper J, Southey M, ABCFS, Beckmann MW, Fasching PA, BBCC et al. (2009)
    Association of ESR1 gene tagging SNPs with breast cancer risk
    Hum Mol Genet, 18 (6), 1131-9
    DOI 10.1093/hmg/ddn429, PubMed 19126777
  7. Figueiredo JC, Haile RW, Bernstein L, Malone KE, Largent J, Langholz B, Lynch CF, Bertelsen L, Capanu M, Concannon P, Borg A, Børresen-Dale AL, Diep A, Teraoka S, Torngren T, Xue S, Bernstein JL (2009)
    Oral contraceptives and postmenopausal hormones and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers and noncarriers: the WECARE Study
    Breast Cancer Res Treat, 120 (1), 175-83
    DOI 10.1007/s10549-009-0455-5, PubMed 19597986
  8. Gaudet MM, Milne RL, Cox A, Camp NJ, Goode EL, Humphreys MK, Dunning AM, Morrison J, Giles GG, Severi G, Baglietto L, English DR, Couch FJ, Olson JE, Wang X, Chang-Claude J, Flesch-Janys D, Abbas S, Salazar R, Mannermaa A, Kataja V, Kosma VM, Lindblom A, Margolin S, Heikkinen T et al. (2009)
    Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
    Cancer Epidemiol Biomarkers Prev, 18 (5), 1610-6
    DOI 10.1158/1055-9965.EPI-08-0745, PubMed 19423537
  9. Gebre-Medhin S, Broberg K, Jonson T, Gorunova L, von Steyern FV, Brosjö O, Jin Y, Gisselsson D, Panagopoulos I, Mandahl N, Mertens F (2009)
    Telomeric associations correlate with telomere length reduction and clonal chromosome aberrations in giant cell tumor of bone
    Cytogenet Genome Res, 124 (2), 121-7
    DOI 10.1159/000207516, PubMed 19420923
  10. Geigl JB, Obenauf AC, Waldispuehl-Geigl J, Hoffmann EM, Auer M, Hörmann M, Fischer M, Trajanoski Z, Schenk MA, Baumbusch LO, Speicher MR (2009)
    Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays
    Nucleic Acids Res, 37 (15), e105
    DOI 10.1093/nar/gkp526, PubMed 19541849
  11. Glynn SA, Boersma BJ, Howe TM, Edvardsen H, Geisler SB, Goodman JE, Ridnour LA, Lønning PE, Børresen-Dale AL, Naume B, Kristensen VN, Chanock SJ, Wink DA, Ambs S (2009)
    A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide
    Clin Cancer Res, 15 (12), 4165-73
    DOI 10.1158/1078-0432.CCR-09-0119, PubMed 19509150
  12. Kamalakaran S, Kendall J, Zhao X, Tang C, Khan S, Ravi K, Auletta T, Riggs M, Wang Y, Helland A, Naume B, Dimitrova N, Børresen-Dale AL, Hicks J, Lucito R (2009)
    Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
    Nucleic Acids Res, 37 (12), e89
    DOI 10.1093/nar/gkp413, PubMed 19474344
  13. Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna SM, Ciotti M, Das BR, Del Mistro A, Dybikowska A, Giuliano AR, Gudleviciene Z, Gyllensten U, Haws AL, Helland A, Herrington CS, Hildesheim A, Humbey O, Jee SH, Kim JW, Madeleine MM, Menczer J, Ngan HY, Nishikawa A, Niwa Y et al. (2009)
    TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies
    Lancet Oncol, 10 (8), 772-84
    DOI 10.1016/S1470-2045(09)70187-1, PubMed 19625214
  14. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
    Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
    Pharmacogenet Genomics, 19 (10), 751-9
    DOI 10.1097/FPC.0b013e3283304253, PubMed 19741569
  15. Landmark-Høyvik H, Reinertsen KV, Loge JH, Fosså SD, Børresen-Dale AL, Dumeaux V (2009)
    Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors
    Pharmacogenomics J, 9 (5), 333-40
    DOI 10.1038/tpj.2009.27, PubMed 19546881
  16. Leivonen SK, Mäkelä R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, Enerly E, Aakula A, Hellström K, Sahlberg N, Kristensen VN, Børresen-Dale AL, Saviranta P, Perälä M, Kallioniemi O (2009)
    Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
    Oncogene, 28 (44), 3926-36
    DOI 10.1038/onc.2009.241, PubMed 19684618
  17. Lönneborg A, Aarøe J, Dumeaux V, Børresen-Dale AL (2009)
    Found in transcription: gene expression and other novel blood biomarkers for the early detection of breast cancer
    Expert Rev Anticancer Ther, 9 (8), 1115-23
    DOI 10.1586/era.09.31, PubMed 19671031
  18. Muggerud AA, Edgren H, Wolf M, Kleivi K, Dejeux E, Tost J, Sørlie T, Kallioniemi O (2009)
    Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line
    BMC Med Genomics, 2, 26
    DOI 10.1186/1755-8794-2-26, PubMed 19432969
  19. Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB (2009)
    Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
    PLoS One, 4 (5), e5583
    DOI 10.1371/journal.pone.0005583, PubMed 19440550
  20. Olivier M, Petitjean A, Teague J, Forbes S, Dunnick JK, den Dunnen JT, Langerød A, Wilkinson JM, Vihinen M, Cotton RG, Hainaut P, IARC, EC FP6 (2009)
    Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration
    Hum Mutat, 30 (3), 275-82
    DOI 10.1002/humu.20832, PubMed 19006239
  21. Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2009)
    Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
    Mol Oncol, 4 (2), 98-118
    DOI 10.1016/j.molonc.2009.12.001, PubMed 20060370
  22. Prescott TE, Rødningen OK, Bjørnstad A, Stray-Pedersen A (2009)
    Two brothers with a microduplication including the MECP2 gene: rapid head growth in infancy and resolution of susceptibility to infection
    Clin Dysmorphol, 18 (2), 78-82
    DOI 10.1097/MCD.0b013e32831e19cd, PubMed 19057379
  23. Skinningsrud B, Husebye ES, Gilfillan GD, Frengen E, Erichsen A, Gervin K, Ormerod E, Egeland T, Undlien DE (2009)
    X-linked congenital adrenal hypoplasia with hypogonadotropic hypogonadism caused by an inversion disrupting a conserved noncoding element upstream of the NR0B1 (DAX1) gene
    J Clin Endocrinol Metab, 94 (10), 4086-93
    DOI 10.1210/jc.2009-0923, PubMed 19773398
  24. Skotheim RI, Thomassen GO, Eken M, Lind GE, Micci F, Ribeiro FR, Cerveira N, Teixeira MR, Heim S, Rognes T, Lothe RA (2009)
    A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
    Mol Cancer, 8, 5
    DOI 10.1186/1476-4598-8-5, PubMed 19152679
  25. Solvang HK, Nagahara Y, Araki S, Sawada H, Makino S (2009)
    Frequency-Domain Pearson Distribution Approach for Independent Component Analysis (FD-Pearson-ICA) in Blind Source Separation
    IEEE Trans. Audio Speech Lang. Process., 17 (4), 639-649
  26. Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE et al. (2009)
    Complex landscapes of somatic rearrangement in human breast cancer genomes
    Nature, 462 (7276), 1005-10
    DOI 10.1038/nature08645, PubMed 20033038
  27. Sun W, Wright FA, Tang Z, Nordgard SH, Van Loo P, Yu T, Kristensen VN, Perou CM (2009)
    Integrated study of copy number states and genotype calls using high-density SNP arrays
    Nucleic Acids Res, 37 (16), 5365-77
    DOI 10.1093/nar/gkp493, PubMed 19581427
  28. Sørlie T (2009)
    Introducing molecular subtyping of breast cancer into the clinic?
    J Clin Oncol, 27 (8), 1153-4
    DOI 10.1200/JCO.2008.20.6276, PubMed 19204193
  29. Vasen HF, Möslein G, Alonso A, Aretz S, Bernstein I, Bertario L, Blanco I, Bulow S, Burn J, Capella G, Colas C, Engel C, Frayling I, Rahner N, Hes FJ, Hodgson S, Mecklin JP, Møller P, Myrhøj T, Nagengast FM, Parc Y, Ponz de Leon M, Renkonen-Sinisalo L, Sampson JR, Stormorken A et al. (2009)
    Recommendations to improve identification of hereditary and familial colorectal cancer in Europe
    Fam Cancer, 9 (2), 109-15
    DOI 10.1007/s10689-009-9291-3, PubMed 19763885
  30. Zhou W, Muggerud AA, Vu P, Due EU, Sørlie T, Børresen-Dale AL, Wärnberg F, Langerød A (2009)
    Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
    Mol Oncol, 3 (3), 214-9
    DOI 10.1016/j.molonc.2009.03.001, PubMed 19403344

Publications 2008

  1. Alsner J, Jensen V, Kyndi M, Offersen BV, Vu P, Børresen-Dale AL, Overgaard J (2008)
    A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients
    Acta Oncol, 47 (4), 600-7
    DOI 10.1080/02841860802047411, PubMed 18465328
  2. Baumbusch LO, Aarøe J, Johansen FE, Hicks J, Sun H, Bruhn L, Gunderson K, Naume B, Kristensen VN, Liestøl K, Børresen-Dale AL, Lingjaerde OC (2008)
    Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
    BMC Genomics, 9, 379
    DOI 10.1186/1471-2164-9-379, PubMed 18691401
  3. Bergamaschi A, Kim YH, Kwei KA, La Choi Y, Bocanegra M, Langerød A, Han W, Noh DY, Huntsman DG, Jeffrey SS, Børresen-Dale AL, Pollack JR (2008)
    CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
    Mol Oncol, 2 (4), 327-39
    DOI 10.1016/j.molonc.2008.09.004, PubMed 19383354
  4. Bergamaschi A, Tagliabue E, Sørlie T, Naume B, Triulzi T, Orlandi R, Russnes HG, Nesland JM, Tammi R, Auvinen P, Kosma VM, Ménard S, Børresen-Dale AL (2008)
    Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
    J Pathol, 214 (3), 357-67
    DOI 10.1002/path.2278, PubMed 18044827
  5. Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V (2008)
    p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation
    Mol Syst Biol, 4, 229
    DOI 10.1038/msb.2008.65, PubMed 19034270
  6. Concannon P, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Teraoka SN, Diep TA, Jansen L, Atencio DP, Langholz B, Capanu M, Liang X, Begg CB, Thomas DC, Bernstein L, Olsen JH, Malone KE, Lynch CF, Anton-Culver H, Bernstein JL, Women's Environment, Cancer, and Radiation Epidemiology Study Collaborative Group (2008)
    Variants in the ATM gene associated with a reduced risk of contralateral breast cancer
    Cancer Res, 68 (16), 6486-91
    DOI 10.1158/0008-5472.CAN-08-0134, PubMed 18701470
  7. Dong HP, Kleinberg L, Silins I, Flørenes VA, Tropé CG, Risberg B, Nesland JM, Davidson B (2008)
    Death receptor expression is associated with poor response to chemotherapy and shorter survival in metastatic ovarian carcinoma
    Cancer, 112 (1), 84-93
    DOI 10.1002/cncr.23140, PubMed 17985388
  8. Dumeaux V, Børresen-Dale AL, Frantzen JO, Kumle M, Kristensen VN, Lund E (2008)
    Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
    Breast Cancer Res, 10 (1), R13
    DOI 10.1186/bcr1859, PubMed 18271962
  9. Dumeaux V, Lund E, Børresen-Dale AL (2008)
    Comparison of globin RNA processing methods for genome-wide transcriptome analysis from whole blood
    Biomark Med, 2 (1), 11-21
    DOI 10.2217/17520363.2.1.11, PubMed 20477359
  10. Holm R, Kraus I, Skomedal H, Langerød A, Kristensen GB, Lyng H (2008)
    Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma
    Open Virol J, 2, 74-81
    DOI 10.2174/1874357900802010074, PubMed 19440467
  11. Horlings HM, Bergamaschi A, Nordgard SH, Kim YH, Han W, Noh DY, Salari K, Joosse SA, Reyal F, Lingjaerde OC, Kristensen VN, Børresen-Dale AL, Pollack J, van de Vijver MJ (2008)
    ESR1 gene amplification in breast cancer: a common phenomenon?
    Nat Genet, 40 (7), 807-8; author reply 810-2
    DOI 10.1038/ng0708-807, PubMed 18583965
  12. Kristensen VN, Børresen-Dale AL (2008)
    SNPs associated with molecular subtypes of breast cancer: on the usefulness of stratified Genome-wide Association Studies (GWAS) in the identification of novel susceptibility loci
    Mol Oncol, 2 (1), 12-5
    DOI 10.1016/j.molonc.2008.02.003, PubMed 19383324
  13. Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2008)
    Accounting for haplotype phase uncertainty in linkage disequilibrium estimation (vol 32, pg 168, 2008)
    Genet. Epidemiol., 32 (6), 586-587
  14. Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2008)
    Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
    Genet Epidemiol, 32 (2), 168-78
    DOI 10.1002/gepi.20273, PubMed 17968987
  15. Lacroix J, Poët M, Huc L, Morello V, Djerbi N, Ragno M, Rissel M, Tekpli X, Gounon P, Lagadic-Gossmann D, Counillon L (2008)
    Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks
    Biochemistry, 47 (51), 13674-85
    DOI 10.1021/bi801368n, PubMed 19035652
  16. Mellemkjaer L, Dahl C, Olsen JH, Bertelsen L, Guldberg P, Christensen J, Børresen-Dale AL, Stovall M, Langholz B, Bernstein L, Lynch CF, Malone KE, Haile RW, Andersson M, Thomas DC, Concannon P, Capanu M, Boice JD, WECARE Study Collaborative Group, Bernstein JL (2008)
    Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study
    Br J Cancer, 98 (4), 728-33
    DOI 10.1038/sj.bjc.6604228, PubMed 18253122
  17. Nordgard SH, Alnaes GI, Hihn B, Lingjaerde OC, Liestøl K, Tsalenko A, Sørlie T, Lønning PE, Børresen-Dale AL, Kristensen VN (2008)
    Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
    Int J Cancer, 123 (3), 577-85
    DOI 10.1002/ijc.23541, PubMed 18498133
  18. Nordgard SH, Johansen FE, Alnaes GI, Bucher E, Syvänen AC, Naume B, Børresen-Dale AL, Kristensen VN (2008)
    Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients
    Genes Chromosomes Cancer, 47 (8), 680-96
    DOI 10.1002/gcc.20569, PubMed 18398821
  19. Nourissat P, Travert M, Chevanne M, Tekpli X, Rebillard A, Le Moigne-Müller G, Rissel M, Cillard J, Dimanche-Boitrel MT, Lagadic-Gossmann D, Sergent O (2008)
    Ethanol induces oxidative stress in primary rat hepatocytes through the early involvement of lipid raft clustering
    Hepatology, 47 (1), 59-70
    DOI 10.1002/hep.21958, PubMed 18038449
  20. Pietersen AM, Horlings HM, Hauptmann M, Langerød A, Ajouaou A, Cornelissen-Steijger P, Wessels LF, Jonkers J, van de Vijver MJ, van Lohuizen M (2008)
    EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
    Breast Cancer Res, 10 (6), R109
    DOI 10.1186/bcr2214, PubMed 19099573
  21. Rønneberg JA, Tost J, Solvang HK, Alnaes GI, Johansen FE, Brendeford EM, Yakhini Z, Gut IG, Lønning PE, Børresen-Dale AL, Gabrielsen OS, Kristensen VN (2008)
    GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
    Cancer Res, 68 (14), 5562-71
    DOI 10.1158/0008-5472.CAN-07-5828, PubMed 18632608
  22. Saebo S, Almoy T, Aaroe J, Aastveit AH (2008)
    ST-PLS: a multi-directional nearest shrunken centroid type classi er via PLS
    J. Chemometr., 22 (1-2), 54-62
  23. Saebø M, Skjelbred CF, Brekke Li K, Bowitz Lothe IM, Hagen PC, Johnsen E, Tveit KM, Kure EH (2008)
    CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas
    Anticancer Res, 28 (4C), 2289-95
    PubMed 18751408
  24. Solvang HK, Ishizuka K, Fujimoto M (2008)
    Voice activity detection based on adjustable linear prediction and GARCH models
    Speech Commun., 50 (6), 476-486
  25. Suspitsin EN, Due EU, Vu P, Hirvonen A, Børresen-Dale AL, Imyanitov EN (2008)
    TP53 mutations in synchronous and metachronous bilateral breast carcinomas
    Cancer Genet Cytogenet, 184 (2), 119-21
    DOI 10.1016/j.cancergencyto.2008.03.005, PubMed 18617062
  26. Tongbai R, Idelman G, Nordgard SH, Cui W, Jacobs JL, Haggerty CM, Chanock SJ, Børresen-Dale AL, Livingston G, Shaunessy P, Chiang CH, Kristensen VN, Bilke S, Gardner K (2008)
    Transcriptional networks inferred from molecular signatures of breast cancer
    Am J Pathol, 172 (2), 495-509
    DOI 10.2353/ajpath.2008.061079, PubMed 18187569
  27. Vaclavikova R, Nordgard SH, Alnaes GI, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P (2008)
    Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients
    Pharmacogenet Genomics, 18 (3), 263-73
    DOI 10.1097/FPC.0b013e3282f60a91, PubMed 18300948
  28. Waaseth M, Bakken K, Dumeaux V, Olsen KS, Rylander C, Figenschau Y, Lund E (2008)
    Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer postgenome cohort - a cross-sectional analysis
    BMC Womens Health, 8, 1
    DOI 10.1186/1472-6874-8-1, PubMed 18194511
  29. Aavitsland P, Helland A (2008)
    [The selected contagions]
    Tidsskr Nor Laegeforen, 128 (20), 2304
    PubMed 19096483

Publications 2007

  1. Alsner J, Rødningen OK, Overgaard J (2007)
    Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis
    Radiother Oncol, 83 (3), 261-6
    DOI 10.1016/j.radonc.2007.05.001, PubMed 17512072
  2. Annunziata CM, Kleinberg L, Davidson B, Berner A, Gius D, Tchabo N, Steinberg SM, Kohn EC (2007)
    BAG-4/SODD and associated antiapoptotic proteins are linked to aggressiveness of epithelial ovarian cancer
    Clin Cancer Res, 13 (22 Pt 1), 6585-92
    DOI 10.1158/1078-0432.CCR-07-0327, PubMed 18006758
  3. Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
    Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
    BMC Cancer, 7, 197
    DOI 10.1186/1471-2407-7-197, PubMed 17956601
  4. Casalini P, Iorio MV, Berno V, Bergamaschi A, Børresen Dale AL, Gasparini P, Orlandi R, Casati B, Tagliabue E, Ménard S (2007)
    Relationship between p53 and p27 expression following HER2 signaling
    Breast, 16 (6), 597-605
    DOI 10.1016/j.breast.2007.05.007, PubMed 17604627
  5. Chanock SJ, Burdett L, Yeager M, Llaca V, Langerød A, Presswalla S, Kaaresen R, Strausberg RL, Gerhard DS, Kristensen V, Perou CM, Børresen-Dale AL (2007)
    Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
    Breast Cancer Res, 9 (1), R5
    DOI 10.1186/bcr1637, PubMed 17224074
  6. Davidson B, Skrede M, Silins I, Shih IeM, Trope CG, Flørenes VA (2007)
    Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma
    Cancer, 110 (6), 1264-71
    DOI 10.1002/cncr.22918, PubMed 17647260
  7. Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bøhn M, Erikstein B, Helland A, Børresen-Dale AL, Fosså SD (2007)
    Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
    Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
    DOI 10.1016/j.ijrobp.2006.11.009, PubMed 17336217
  8. Edvardsen H, Tefre T, Jansen L, Vu P, Haffty BG, Fosså SD, Kristensen VN, Børresen-Dale AL (2007)
    Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
    Radiat Oncol, 2, 25
    DOI 10.1186/1748-717X-2-25, PubMed 17623063
  9. Garcia-Closas M, Kristensen V, Langerød A, Qi Y, Yeager M, Burdett L, Welch R, Lissowska J, Peplonska B, Brinton L, Gerhard DS, Gram IT, Perou CM, Børresen-Dale AL, Chanock S (2007)
    Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
    Int J Cancer, 121 (11), 2532-8
    DOI 10.1002/ijc.22985, PubMed 17683073
  10. Garcia-Closas M, Troester MA, Qi Y, Langerød A, Yeager M, Lissowska J, Brinton L, Welch R, Peplonska B, Gerhard DS, Gram IT, Kristensen V, Børresen-Dale AL, Chanock S, Perou CM (2007)
    Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
    Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
    DOI 10.1158/1055-9965.EPI-07-0449, PubMed 18006915
  11. Hoffman A, Horwitz E, Hess S, Cohen-Poradosu R, Kleinberg L, Edelberg A, Shapiro M (2007)
    Implications on emergence of antimicrobial resistance as a critical aspect in the design of oral sustained release delivery systems of antimicrobials
    Pharm Res, 25 (3), 667-71
    DOI 10.1007/s11095-007-9373-6, PubMed 17939018
  12. Holme JA, Gorria M, Arlt VM, Ovrebø S, Solhaug A, Tekpli X, Landvik NE, Huc L, Fardel O, Lagadic-Gossmann D (2007)
    Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells
    Chem Biol Interact, 167 (1), 41-55
    DOI 10.1016/j.cbi.2007.01.008, PubMed 17289009
  13. Huc L, Tekpli X, Holme JA, Rissel M, Solhaug A, Gardyn C, Le Moigne G, Gorria M, Dimanche-Boitrel MT, Lagadic-Gossmann D (2007)
    c-Jun NH2-terminal kinase-related Na+/H+ exchanger isoform 1 activation controls hexokinase II expression in benzo(a)pyrene-induced apoptosis
    Cancer Res, 67 (4), 1696-705
    DOI 10.1158/0008-5472.CAN-06-2327, PubMed 17308111
  14. Kapp AV, Jeffrey SS, Langerod A, Borresen-Dale AL, Han W, Noh DY, Bukholm IRK, Nicolau M, Brown PO, Tibshirani R (2007)
    Discovery and validation of breast cancer subtypes (vol 8, pg 101, 2007)
    BMC Genomics, 8, 101
  15. Kellen E, Hemelt M, Broberg K, Golka K, Kristensen VN, Hung RJ, Matullo G, Mittal RD, Porru S, Povey A, Schulz WA, Shen J, Buntinx F, Zeegers MP, Taioli E (2007)
    Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (11), 1221-30
    DOI 10.1093/aje/kwm003, PubMed 17404387
  16. Kleivi K, Lind GE, Diep CB, Meling GI, Brandal LT, Nesland JM, Myklebost O, Rognum TO, Giercksky KE, Skotheim RI, Lothe RA (2007)
    Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
    Mol Cancer, 6, 2
    DOI 10.1186/1476-4598-6-2, PubMed 17201907
  17. Knappskog S, Chrisanthar R, Staalesen V, Børresen-Dale AL, Gram IT, Lillehaug JR, Lønning PE (2007)
    Mutations and polymorphisms of the p21B transcript in breast cancer
    Int J Cancer, 121 (4), 908-10
    DOI 10.1002/ijc.22777, PubMed 17443496
  18. Landmark H, Nahas SA, Aarøe J, Gatti R, Børresen-Dale AL, Rødningen OK (2007)
    Transcriptional response to ionizing radiation in human radiation sensitive cell lines
    Radiother Oncol, 83 (3), 256-60
    DOI 10.1016/j.radonc.2007.04.017, PubMed 17512073
  19. Langerød A, Zhao H, Borgan Ø, Nesland JM, Bukholm IR, Ikdahl T, Kåresen R, Børresen-Dale AL, Jeffrey SS (2007)
    TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    Breast Cancer Res, 9 (3), R30
    DOI 10.1186/bcr1675, PubMed 17504517
  20. Lorentzen A, Vogel LK, Lewinsky RH, Saebø M, Skjelbred CF, Godiksen S, Hoff G, Tveit KM, Lothe IM, Ikdahl T, Kure EH, Mitchelmore C (2007)
    Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
    BMC Cancer, 7, 192
    DOI 10.1186/1471-2407-7-192, PubMed 17935612
  21. Lund E, Bakken K, Dumeaux V, Andersen V, Kumle M (2007)
    Hormone replacement therapy and breast cancer in former users of oral contraceptives--The Norwegian Women and Cancer study
    Int J Cancer, 121 (3), 645-8
    DOI 10.1002/ijc.22699, PubMed 17372914
  22. Lund E, Dumeaux V, Braaten T, Hjartåker A, Engeset D, Skeie G, Kumle M (2007)
    Cohort profile: The Norwegian Women and Cancer Study--NOWAC--Kvinner og kreft
    Int J Epidemiol, 37 (1), 36-41
    DOI 10.1093/ije/dym137, PubMed 17644530
  23. McLaughlin JR, Risch HA, Lubinski J, Moller P, Ghadirian P, Lynch H, Karlan B, Fishman D, Rosen B, Neuhausen SL, Offit K, Kauff N, Domchek S, Tung N, Friedman E, Foulkes W, Sun P, Narod SA, Hereditary Ovarian Cancer Clinical Study Group (2007)
    Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study
    Lancet Oncol, 8 (1), 26-34
    DOI 10.1016/S1470-2045(06)70983-4, PubMed 17196508
  24. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
    Mol Oncol, 1 (2), 160-71
    DOI 10.1016/j.molonc.2007.03.004, PubMed 19383292
  25. Nicolau M, Tibshirani R, Børresen-Dale AL, Jeffrey SS (2007)
    Disease-specific genomic analysis: identifying the signature of pathologic biology
    Bioinformatics, 23 (8), 957-65
    DOI 10.1093/bioinformatics/btm033, PubMed 17277331
  26. Nordgard SH, Johansen FE, Alnaes GI, Naume B, Børresen-Dale AL, Kristensen VN (2007)
    Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
    Breast Cancer Res, 9 (6), 113
    DOI 10.1186/bcr1784, PubMed 18036273
  27. Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN (2007)
    ABCB1 and GST polymorphisms associated with TP53 status in breast cancer
    Pharmacogenet Genomics, 17 (2), 127-36
    DOI 10.1097/FPC.0b013e328011abaa, PubMed 17301692
  28. Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M (2007)
    TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
    Oncogene, 26 (15), 2157-65
    DOI 10.1038/sj.onc.1210302, PubMed 17401424
  29. Rebillard A, Tekpli X, Meurette O, Sergent O, LeMoigne-Muller G, Vernhet L, Gorria M, Chevanne M, Christmann M, Kaina B, Counillon L, Gulbins E, Lagadic-Gossmann D, Dimanche-Boitrel MT (2007)
    Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells
    Cancer Res, 67 (16), 7865-74
    DOI 10.1158/0008-5472.CAN-07-0353, PubMed 17699793
  30. Riise R, Ygge J, Lindman C, Stray-Pedersen A, Bek T, Rødningen OK, Heiberg A (2007)
    Ocular findings in Norwegian patients with ataxia-telangiectasia: a 5 year prospective cohort study
    Acta Ophthalmol Scand, 85 (5), 557-62
    DOI 10.1111/j.1600-0420.2007.00890.x, PubMed 17376192
  31. Roca X, Olson AJ, Rao AR, Enerly E, Kristensen VN, Børresen-Dale AL, Andresen BS, Krainer AR, Sachidanandam R (2007)
    Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
    Genome Res, 18 (1), 77-87
    DOI 10.1101/gr.6859308, PubMed 18032726
  32. Rødningen OK, Børresen-Dale AL, Alsner J, Hastie T, Overgaard J (2007)
    Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis
    Radiother Oncol, 86 (3), 314-20
    DOI 10.1016/j.radonc.2007.09.013, PubMed 17963910
  33. Sikkeland LI, Haug T, Stangeland AM, Flatberg G, Søstrand P, Halvorsen B, Kongerud J (2007)
    Airway inflammation in paper mill workers
    J Occup Environ Med, 49 (10), 1135-42
    DOI 10.1097/JOM.0b013e31814b2e87, PubMed 18000418
  34. Sikkeland LI, Kongerud J, Stangeland AM, Haug T, Alexis NE (2007)
    Macrophage enrichment from induced sputum
    Thorax, 62 (6), 558-9
    DOI 10.1136/thx.2006.073544, PubMed 17536036
  35. Stormorken AT, Clark N, Grindedal E, Maehle L, Møller P (2007)
    Prevention of colorectal cancer by colonoscopic surveillance in families with hereditary colorectal cancer
    Scand J Gastroenterol, 42 (5), 611-7
    DOI 10.1080/00365520601010230, PubMed 17454882
  36. Stray-Pedersen A, Borresen-Dale AL, Paus E, Lindman CR, Burgers T, Abrahamsen TG (2007)
    Alpha fetoprotein is increasing with age in ataxia-telangiectasia
    Eur J Paediatr Neurol, 11 (6), 375-80
    DOI 10.1016/j.ejpn.2007.04.001, PubMed 17540590
  37. Størvold GL, Gjernes E, Askautrud HA, Børresen-Dale AL, Perou CM, Frengen E (2007)
    A retroviral vector for siRNA expression in mammalian cells
    Mol Biotechnol, 35 (3), 275-82
    DOI 10.1007/BF02686013, PubMed 17652791
  38. Suspitsin EN, Sokolenko AP, Togo AV, Lazareva YR, Turkevich EA, Matsko DE, Henrich KO, Borresen-Dale AL, Schwab M, Cornelisse CJ, Imyanitov EN (2007)
    Nonrandom distribution of oncogene amplifications in bilateral breast carcinomas: Possible role of host factors and survival bias
    Int J Cancer, 120 (2), 297-302
    DOI 10.1002/ijc.22265, PubMed 17066426
  39. Sørlie T (2007)
    Molecular classification of breast tumors: toward improved diagnostics and treatments
    Methods Mol Biol, 360, 91-114
    DOI 10.1385/1-59745-165-7:91, PubMed 17172726
  40. Vasen HF, Möslein G, Alonso A, Bernstein I, Bertario L, Blanco I, Burn J, Capella G, Engel C, Frayling I, Friedl W, Hes FJ, Hodgson S, Mecklin JP, Møller P, Nagengast F, Parc Y, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Wijnen J (2007)
    Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)
    J Med Genet, 44 (6), 353-62
    DOI 10.1136/jmg.2007.048991, PubMed 17327285
  41. Wang Y, Kristensen GB, Børresen-Dale AL, Helland A (2007)
    TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients
    Ann Oncol, 18 (5), 964-6
    DOI 10.1093/annonc/mdm134, PubMed 17488735
  42. Yosef N, Yakhini Z, Tsalenko A, Kristensen V, Børresen-Dale AL, Ruppin E, Sharan R (2007)
    A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
    Bioinformatics, 23 (2), e91-8
    DOI 10.1093/bioinformatics/btl298, PubMed 17237111

Publications 2006

  1. Anensen N, Skavland J, Stapnes C, Ryningen A, Børresen-Dale AL, Gjertsen BT, Bruserud Ø (2006)
    Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated with valproic acid, theophyllamine and all-trans retinoic acid: a case report
    Leukemia, 20 (4), 734-6
    DOI 10.1038/sj.leu.2404117, PubMed 16437140
  2. Baumbusch LO, Myhre S, Langerød A, Bergamaschi A, Geisler SB, Lønning PE, Deppert W, Dornreiter I, Børresen-Dale AL (2006)
    Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters
    Mol Cancer, 5, 47
    DOI 10.1186/1476-4598-5-47, PubMed 17054774
  3. Bergamaschi A, Kim YH, Wang P, Sørlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Børresen-Dale AL, Pollack JR (2006)
    Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
    Genes Chromosomes Cancer, 45 (11), 1033-40
    DOI 10.1002/gcc.20366, PubMed 16897746
  4. Brandal P, Bjerkehagen B, Heim S (2006)
    Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology
    J Pathol, 208 (3), 388-94
    DOI 10.1002/path.1879, PubMed 16308870
  5. Brandal P, Lie AK, Bassarova A, Svindland A, Risberg B, Danielsen H, Heim S (2006)
    Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas
    Mod Pathol, 19 (2), 186-94
    DOI 10.1038/modpathol.3800499, PubMed 16258504
  6. Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO (2006)
    Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
    PLoS Med, 3 (3), e47
    DOI 10.1371/journal.pmed.0030047, PubMed 16417408
  7. Clausen OP, Aass HC, Beigi M, Purdie KJ, Proby CM, Brown VL, Mattingsdal M, Micci F, Kølvraa S, Bolund L, Deangelis PM (2006)
    Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization
    J Invest Dermatol, 126 (10), 2308-15
    DOI 10.1038/sj.jid.5700375, PubMed 16728973
  8. Crockford GP, Linger R, Hockley S, Dudakia D, Johnson L, Huddart R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, Bonaïti-Pellié C, Heidenreich A, Albers P, Olah E, Geczi L, Bodrogi I, Ormiston WJ, Daly PA, Guilford P, Fosså SD et al. (2006)
    Genome-wide linkage screen for testicular germ cell tumour susceptibility loci
    Hum Mol Genet, 15 (3), 443-51
    DOI 10.1093/hmg/ddi459, PubMed 16407372
  9. da Silva Ribeiro FR (2006)
    Diagnostic and prognostic value of molecular cytogenetic analyses of sextant biopsies from prostate cancer suspects
    Crit Rev Oncog, 12 (3-4), 303-4; discussion 304
    PubMed 17425511
  10. Davidson B, Konstantinovsky S, Kleinberg L, Nguyen MT, Bassarova A, Kvalheim G, Nesland JM, Reich R (2006)
    The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma
    Gynecol Oncol, 102 (3), 453-61
    DOI 10.1016/j.ygyno.2006.01.034, PubMed 16494928
  11. Davidson B, Zhang Z, Kleinberg L, Li M, Flørenes VA, Wang TL, Shih IeM (2006)
    Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from diffuse malignant peritoneal mesothelioma
    Clin Cancer Res, 12 (20 Pt 1), 5944-50
    DOI 10.1158/1078-0432.CCR-06-1059, PubMed 17062665
  12. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC, Lothe RA (2006)
    The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
    Genes Chromosomes Cancer, 45 (1), 31-41
    DOI 10.1002/gcc.20261, PubMed 16145679
  13. Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
    Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
    Int J Cancer, 118 (11), 2877-81
    DOI 10.1002/ijc.21709, PubMed 16381016
  14. Dumeaux V, Johansen J, Børresen-Dale AL, Lund E (2006)
    Gene expression profiling of whole-blood samples from women exposed to hormone replacement therapy
    Mol Cancer Ther, 5 (4), 868-76
    DOI 10.1158/1535-7163.MCT-05-0329, PubMed 16648556
  15. Edvardsen H, Irene Grenaker Alnaes G, Tsalenko A, Mulcahy T, Yuryev A, Lindersson M, Lien S, Omholt S, Syvänen AC, Børresen-Dale AL, Kristensen VN (2006)
    Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
    Pharmacogenet Genomics, 16 (3), 207-17
    DOI 10.1097/01.fpc.0000194422.12770.fb, PubMed 16495780
  16. Friedman E, Kotsopoulos J, Lubinski J, Lynch HT, Ghadirian P, Neuhausen SL, Isaacs C, Weber B, Foulkes WD, Moller P, Rosen B, Kim-Sing C, Gershoni-Baruch R, Ainsworth P, Daly M, Tung N, Eisen A, Olopade OI, Karlan B, Saal HM, Garber JE, Rennert G, Gilchrist D, Eng C, Offit K et al. (2006)
    Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers
    Breast Cancer Res, 8 (2), R15
    DOI 10.1186/bcr1387, PubMed 16563180
  17. Geirdal AØ, Maehle L, Heimdal K, Stormorken A, Møller P, Dahl AA (2006)
    Quality of life and its relation to cancer-related stress in women of families with hereditary cancer without demonstrated mutation
    Qual Life Res, 15 (3), 461-70
    DOI 10.1007/s11136-005-3008-3, PubMed 16547785
  18. Gorria M, Tekpli X, Sergent O, Huc L, Gaboriau F, Rissel M, Chevanne M, Dimanche-Boitrel MT, Lagadic-Gossmann D (2006)
    Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells: protection by exogenous cholesterol
    Ann N Y Acad Sci, 1090, 108-12
    DOI 10.1196/annals.1378.011, PubMed 17384252
  19. Heikkinen K, Rapakko K, Karppinen SM, Erkko H, Knuutila S, Lundán T, Mannermaa A, Børresen-Dale AL, Borg A, Barkardottir RB, Petrini J, Winqvist R (2006)
    RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
    Carcinogenesis, 27 (8), 1593-9
    DOI 10.1093/carcin/bgi360, PubMed 16474176
  20. Helland A, Johnsen H, Frøyland C, Landmark HB, Saetersdal AB, Holmen MM, Gjertsen T, Nesland JM, Ottestad W, Jeffrey SS, Ottestad LO, Rodningen OK, Sherlock G, Børresen-Dale AL (2006)
    Radiation-induced effects on gene expression: an in vivo study on breast cancer
    Radiother Oncol, 80 (2), 230-5
    DOI 10.1016/j.radonc.2006.07.007, PubMed 16890317
  21. Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, Børresen-Dale AL, Naume B, Schlicting E, Norton L, Hägerström T, Skoog L, Auer G, Månér S, Lundin P, Zetterberg A (2006)
    Novel patterns of genome rearrangement and their association with survival in breast cancer
    Genome Res, 16 (12), 1465-79
    DOI 10.1101/gr.5460106, PubMed 17142309
  22. Huc L, Rissel M, Solhaug A, Tekpli X, Gorria M, Torriglia A, Holme JA, Dimanche-Boitrel MT, Lagadic-Gossmann D (2006)
    Multiple apoptotic pathways induced by p53-dependent acidification in benzo[a]pyrene-exposed hepatic F258 cells
    J Cell Physiol, 208 (3), 527-37
    DOI 10.1002/jcp.20686, PubMed 16688778
  23. Ikonomou IM, Tierens A, Troen G, Aamot HV, Heim S, Lauritzsen GF, Vålerhaugen H, Delabie J (2006)
    Peripheral T-cell lymphoma with involvement of the expanded mantle zone
    Virchows Arch, 449 (1), 78-87
    DOI 10.1007/s00428-005-0123-z, PubMed 16633785
  24. Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT (2006)
    Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53
    Blood, 109 (6), 2589-96
    DOI 10.1182/blood-2006-02-004234, PubMed 17105820
  25. Jensen T, Retterstøl LJ, Sandset PM, Godal HC, Skjønsberg OH (2006)
    A daily glass of red wine induces a prolonged reduction in plasma viscosity: a randomized controlled trial
    Blood Coagul Fibrinolysis, 17 (6), 471-6
    DOI 10.1097/01.mbc.0000240920.72930.63, PubMed 16905951
  26. Kapp AV, Jeffrey SS, Langerød A, Børresen-Dale AL, Han W, Noh DY, Bukholm IR, Nicolau M, Brown PO, Tibshirani R (2006)
    Discovery and validation of breast cancer subtypes
    BMC Genomics, 7, 231
    DOI 10.1186/1471-2164-7-231, PubMed 16965636
  27. Kleivi K (2006)
    Advances in the genetics and epigenetics of gene regulation and human disease
    Genome Biol, 7 (8), 325
    DOI 10.1186/gb-2006-7-8-325, PubMed 16934107
  28. Kristensen V, Aven T, Ford D (2006)
    A new perspective on Renn and Klinke's approach to risk evaluation and management
    Reliab. Eng. Syst. Saf., 91 (4), 421-432
  29. Kristensen VN, Edvardsen H, Tsalenko A, Nordgard SH, Sørlie T, Sharan R, Vailaya A, Ben-Dor A, Lønning PE, Lien S, Omholt S, Syvänen AC, Yakhini Z, Børresen-Dale AL (2006)
    Genetic variation in putative regulatory loci controlling gene expression in breast cancer
    Proc Natl Acad Sci U S A, 103 (20), 7735-40
    DOI 10.1073/pnas.0601893103, PubMed 16684880
  30. Kristensen VN, Tsalenko A, Geisler J, Faldaas A, Grenaker GI, Lingjaerde OC, Fjeldstad S, Yakhini Z, Lønning PE, Børresen-Dale AL (2006)
    Multilocus analysis of SNP and metabolic data within a given pathway
    BMC Genomics, 7, 5
    DOI 10.1186/1471-2164-7-5, PubMed 16412218
  31. Lahermo P, Liljedahl U, Alnaes G, Axelsson T, Brookes AJ, Ellonen P, Groop PH, Halldén C, Holmberg D, Holmberg K, Keinänen M, Kepp K, Kere J, Kiviluoma P, Kristensen V, Lindgren C, Odeberg J, Osterman P, Parkkonen M, Saarela J, Sterner M, Strömqvist L, Talas U, Wessman M, Palotie A et al. (2006)
    A quality assessment survey of SNP genotyping laboratories
    Hum Mutat, 27 (7), 711-4
    DOI 10.1002/humu.20346, PubMed 16786507
  32. Langholz B, Bernstein JL, Bernstein L, Olsen JH, Børresen-Dale AL, Rosenstein BS, Gatti RA, WECARE Study Collaborative Group, Concannon P (2006)
    On the proposed association of the ATM variants 5557G>A and IVS38-8T>C and bilateral breast cancer
    Int J Cancer, 119 (3), 724-5
    DOI 10.1002/ijc.21876, PubMed 16496408
  33. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
    ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
    Cell Oncol, 28 (5-6), 259-72
    PubMed 17167179
  34. Lønning PE, Børresen-Dale AL (2006)
    Interaction between p53 staining and high-dose chemotherapy in breast cancer
    Clin Cancer Res, 12 (7 Pt 1), 2289
    DOI 10.1158/1078-0432.CCR-06-0129, PubMed 16609046
  35. Micci F, Panagopoulos I, Bjerkehagen B, Heim S (2006)
    Consistent rearrangement of chromosomal band 6p21 with generation of fusion genes JAZF1/PHF1 and EPC1/PHF1 in endometrial stromal sarcoma
    Cancer Res, 66 (1), 107-12
    DOI 10.1158/0008-5472.CAN-05-2485, PubMed 16397222
  36. Muggerud AA, Johnsen H, Barnes DA, Steel A, Lønning PE, Naume B, Sørlie T, Børresen-Dale AL (2006)
    Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes
    BMC Cancer, 6, 59
    DOI 10.1186/1471-2407-6-59, PubMed 16536878
  37. Narod SA, Lubinski J, Ghadirian P, Lynch HT, Moller P, Foulkes WD, Rosen B, Kim-Sing C, Isaacs C, Domchek S, Sun P, Hereditary Breast Cancer Clinical Study Group (2006)
    Screening mammography and risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study
    Lancet Oncol, 7 (5), 402-6
    DOI 10.1016/S1470-2045(06)70624-6, PubMed 16648044
  38. Olivier M, Langerød A, Carrieri P, Bergh J, Klaar S, Eyfjord J, Theillet C, Rodriguez C, Lidereau R, Bièche I, Varley J, Bignon Y, Uhrhammer N, Winqvist R, Jukkola-Vuorinen A, Niederacher D, Kato S, Ishioka C, Hainaut P, Børresen-Dale AL (2006)
    The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer
    Clin Cancer Res, 12 (4), 1157-67
    DOI 10.1158/1078-0432.CCR-05-1029, PubMed 16489069
  39. Paracchini V, Raimondi S, Gram IT, Kang D, Kocabas NA, Kristensen VN, Li D, Parl FF, Rylander-Rudqvist T, Soucek P, Zheng W, Wedren S, Taioli E (2006)
    Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (2), 115-25
    DOI 10.1093/aje/kwj365, PubMed 17053044
  40. Ribeiro FR, Diep CB, Jerónimo C, Henrique R, Lopes C, Eknaes M, Lingjaerde OC, Lothe RA, Teixeira MR (2006)
    Statistical dissection of genetic pathways involved in prostate carcinogenesis
    Genes Chromosomes Cancer, 45 (2), 154-63
    DOI 10.1002/gcc.20279, PubMed 16235241
  41. Ribeiro FR, Henrique R, Hektoen M, Berg M, Jerónimo C, Teixeira MR, Lothe RA (2006)
    Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
    Mol Cancer, 5, 33
    DOI 10.1186/1476-4598-5-33, PubMed 16952311
  42. Rudkin TM, Hamel N, Galvez M, Hogervorst F, Gille JJ, Møller P, Apold J, Foulkes WD (2006)
    The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations
    BMC Med Genet, 7, 15
    DOI 10.1186/1471-2350-7-15, PubMed 16509964
  43. Schaad K, Strömbeck B, Mandahl N, Andersen MK, Heim S, Mertens F, Johansson B (2006)
    FISH mapping of i(7q) in acute leukemias and myxoid liposarcoma reveals clustered breakpoints in 7p11.2: implications for formation and pathogenetic outcome of the idic(7)(p11.2)
    Cytogenet Genome Res, 114 (2), 126-30
    DOI 10.1159/000093327, PubMed 16825763
  44. Shaposhnikov SA, Akopov SB, Chernov IP, Thomsen PD, Joergensen C, Collins AR, Frengen E, Nikolaev LG (2006)
    A map of nuclear matrix attachment regions within the breast cancer loss-of-heterozygosity region on human chromosome 16q22.1
    Genomics, 89 (3), 354-61
    DOI 10.1016/j.ygeno.2006.11.003, PubMed 17188460
  45. Storlazzi CT, Brekke HR, Mandahl N, Brosjö O, Smeland S, Lothe RA, Mertens F (2006)
    Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
    J Pathol, 209 (4), 492-500
    DOI 10.1002/path.1998, PubMed 16721726
  46. Stormorken AT, Hoff G, Norstein J, Bowitz-Lothe IM, Hanslien E, Grindedal E, Møller P (2006)
    Estimated prevalence of hereditary cancers and the need for surveillance in a Norwegian county, Telemark
    Scand J Gastroenterol, 41 (1), 71-9
    DOI 10.1080/00365520510023891, PubMed 16373279
  47. Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE (2006)
    The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer
    Clin Cancer Res, 12 (20 Pt 1), 6000-4
    DOI 10.1158/1078-0432.CCR-05-2822, PubMed 17062672
  48. Sørlie T, Perou CM, Fan C, Geisler S, Aas T, Nobel A, Anker G, Akslen LA, Botstein D, Børresen-Dale AL, Lønning PE (2006)
    Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
    Mol Cancer Ther, 5 (11), 2914-8
    DOI 10.1158/1535-7163.MCT-06-0126, PubMed 17121939
  49. Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL (2006)
    Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
    BMC Genomics, 7, 127
    DOI 10.1186/1471-2164-7-127, PubMed 16729877
  50. Tavtigian SV, Pierotti MA, Børresen-Dale AL (2006)
    International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy'
    Breast Cancer Res, 8 (6), 303
    DOI 10.1186/bcr1609, PubMed 17096863
  51. Tommiska J, Jansen L, Kilpivaara O, Edvardsen H, Kristensen V, Tamminen A, Aittomäki K, Blomqvist C, Børresen-Dale AL, Nevanlinna H (2006)
    ATM variants and cancer risk in breast cancer patients from Southern Finland
    BMC Cancer, 6, 209
    DOI 10.1186/1471-2407-6-209, PubMed 16914028
  52. Torlakovic EE, Aamot HV, Heim S (2006)
    A marginal zone phenotype in follicular lymphoma with t(14;18) is associated with secondary cytogenetic aberrations typical of marginal zone lymphoma
    J Pathol, 209 (2), 258-64
    DOI 10.1002/path.1981, PubMed 16583359
  53. Tsalenko A, Sharan R, Kristensen V, Edvardsen H, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2006)
    Analysis of SNP-expression association matrices
    J Bioinform Comput Biol, 4 (2), 259-74
    PubMed 16819783
  54. von Eyben FE, Jacobsen GK, Skotheim RI, von der Maase H, Rorth M (2006)
    Precursor lesions in testis and dysgenetic gonads
    Hum Pathol, 37 (6), 773; author reply 774
    DOI 10.1016/j.humpath.2006.01.006, PubMed 16733221
  55. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MMO, Olivier M, Skomedal H, Hainaut P, Trope CG, Abeler VM, Nesland JM, Borresen-Dale AL, Helland A (2006)
    Effect of the codon 72 polymorphism (c.215G > C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma (vol 24, pg 21, 2004)
    Hum. Mutat., 27 (2), 209-210
  56. Aamot HV, Tjønnfjord GE, Delabie J, Heim S (2006)
    Molecular cytogenetic analysis of leukemic mantle cell lymphoma with a cryptic t(11;14)
    Cancer Genet Cytogenet, 165 (2), 172-5
    DOI 10.1016/j.cancergencyto.2005.08.012, PubMed 16527613

Publications 2005

  1. Agesen TH, Flørenes VA, Molenaar WM, Lind GE, Berner JM, Plaat BE, Komdeur R, Myklebost O, van den Berg E, Lothe RA (2005)
    Expression patterns of cell cycle components in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors
    J Neuropathol Exp Neurol, 64 (1), 74-81
    DOI 10.1093/jnen/64.1.74, PubMed 15715087
  2. Aven T, Kristensen V (2005)
    Perspectives on risk: review and discussion of the basis for establishing a unified and holistic approach
    Reliab. Eng. Syst. Saf., 90 (1), 1-14
  3. Benetkiewicz M, Wang Y, Schaner M, Wang P, Mantripragada KK, Buckley PG, Kristensen G, Børresen-Dale AL, Dumanski JP (2005)
    High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas
    Genes Chromosomes Cancer, 42 (3), 228-37
    DOI 10.1002/gcc.20128, PubMed 15578687
  4. Bercovich D, Friedlander Y, Korem S, Houminer A, Hoffman A, Kleinberg L, Shochat C, Leitersdorf E, Meiner V (2005)
    The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia
    Atherosclerosis, 185 (1), 97-107
    DOI 10.1016/j.atherosclerosis.2005.05.025, PubMed 16002074
  5. Brandal P, Bjerkehagen B, Danielsen H, Heim S (2005)
    Chromosome 7 abnormalities are common in chordomas
    Cancer Genet Cytogenet, 160 (1), 15-21
    DOI 10.1016/j.cancergencyto.2004.11.016, PubMed 15949565
  6. Brandal P, Busund LT, Heim S (2005)
    Chromosome abnormalities in juxtaglomerular cell tumors
    Cancer, 104 (3), 504-10
    DOI 10.1002/cncr.21205, PubMed 15968688
  7. Castro P, Eknaes M, Teixeira MR, Danielsen HE, Soares P, Lothe RA, Sobrinho-Simões M (2005)
    Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes
    J Pathol, 206 (3), 305-11
    DOI 10.1002/path.1772, PubMed 15852498
  8. Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ (2005)
    Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
    Proc Natl Acad Sci U S A, 102 (10), 3738-43
    DOI 10.1073/pnas.0409462102, PubMed 15701700
  9. Come SE, Buzdar AU, Ingle JN, Arteaga CL, Brodie AM, Colditz GA, Johnston SR, Kristensen VN, Lønning PE, McDonnell DP, Osborne CK, Russo J, Santen RJ, Yee D, Hart CS (2005)
    Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement
    Clin Cancer Res, 11 (2 Pt 2), 861s-4s
    PubMed 15701878
  10. Cullinane CA, Lubinski J, Neuhausen SL, Ghadirian P, Lynch HT, Isaacs C, Weber B, Moller P, Offit K, Kim-Sing C, Friedman E, Randall S, Pasini B, Ainsworth P, Gershoni-Baruch R, Foulkes WD, Klijn J, Tung N, Rennert G, Olopade O, Couch F, Wagner T, Olsson H, Sun P, Weitzel JN et al. (2005)
    Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers
    Int J Cancer, 117 (6), 988-91
    DOI 10.1002/ijc.21273, PubMed 15986445
  11. Eisen A, Lubinski J, Klijn J, Moller P, Lynch HT, Offit K, Weber B, Rebbeck T, Neuhausen SL, Ghadirian P, Foulkes WD, Gershoni-Baruch R, Friedman E, Rennert G, Wagner T, Isaacs C, Kim-Sing C, Ainsworth P, Sun P, Narod SA (2005)
    Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study
    J Clin Oncol, 23 (30), 7491-6
    DOI 10.1200/JCO.2004.00.7138, PubMed 16234515
  12. Geirdal AØ, Reichelt JG, Dahl AA, Heimdal K, Maehle L, Stormorken A, Møller P (2005)
    Psychological distress in women at risk of hereditary breast/ovarian or HNPCC cancers in the absence of demonstrated mutations
    Fam Cancer, 4 (2), 121-6
    DOI 10.1007/s10689-004-7995-y, PubMed 15951962
  13. Hofer MD, Browne TJ, He L, Skotheim RI, Lothe RA, Rubin MA (2005)
    Identification of two molecular groups of seminomas by using expression and tissue microarrays
    Clin Cancer Res, 11 (16), 5722-9
    DOI 10.1158/1078-0432.CCR-05-0533, PubMed 16115909
  14. Hope Q, Bullock S, Evans C, Meitz J, Hamel N, Edwards SM, Severi G, Dearnaley D, Jhavar S, Southgate C, Falconer A, Dowe A, Muir K, Houlston RS, Engert JC, Roquis D, Sinnett D, Simard J, Heimdal K, Møller P, Maehle L, Badzioch M, Eeles RA, Easton DF, English DR et al. (2005)
    Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer
    Cancer Epidemiol Biomarkers Prev, 14 (2), 397-402
    DOI 10.1158/1055-9965.EPI-04-0202, PubMed 15734964
  15. Kleivi K, Diep CB, Pandis N, Heim S, Teixeira MR, Lothe RA (2005)
    TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas
    J Pathol, 207 (1), 14-9
    DOI 10.1002/path.1812, PubMed 16007576
  16. Kotsopoulos J, Lubinski J, Neuhausen SL, Lynch HT, Rosen B, Ainsworth P, Moller P, Ghadirian P, Isaacs C, Karlan B, Sun P, Narod SA (2005)
    Hormone replacement therapy and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers
    Gynecol Oncol, 100 (1), 83-8
    DOI 10.1016/j.ygyno.2005.07.110, PubMed 16137751
  17. Kringen P, Bergamaschi A, Due EU, Wang Y, Tagliabue E, Nesland JM, Nehman A, Tönisson N, Børresen-Dale AL (2005)
    Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas
    Biotechniques, 39 (5), 755-61
    DOI 10.2144/000112000, PubMed 16312222
  18. Kringen P, Wang Y, Dumeaux V, Nesland JM, Kristensen G, Borresen-Dale AL, Dorum A (2005)
    TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
    BMC Cancer, 5, 134
    DOI 10.1186/1471-2407-5-134, PubMed 16229746
  19. Kristensen VN, Sørlie T, Geisler J, Langerød A, Yoshimura N, Kåresen R, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
    Clin Cancer Res, 11 (2 Pt 2), 878s-83s
    PubMed 15701881
  20. Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
    J Steroid Biochem Mol Biol, 95 (1-5), 105-11
    DOI 10.1016/j.jsbmb.2005.04.028, PubMed 16023338
  21. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Henrique R, Saatcioglu F, Esteller M, Teixeira MR, Lothe RA (2005)
    The loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylation
    Mol Cancer, 4 (1), 8
    DOI 10.1186/1476-4598-4-8, PubMed 15691383
  22. Lønning PE, Sørlie T, Børresen-Dale AL (2005)
    Genomics in breast cancer-therapeutic implications
    Nat Clin Pract Oncol, 2 (1), 26-33
    DOI 10.1038/ncponc0072, PubMed 16264853
  23. Maguire P, Margolin S, Skoglund J, Sun XF, Gustafsson JA, Børresen-Dale AL, Lindblom A (2005)
    Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer
    Breast Cancer Res Treat, 94 (2), 145-52
    DOI 10.1007/s10549-005-7697-7, PubMed 16261413
  24. Olsen JH, Hahnemann JM, Børresen-Dale AL, Tretli S, Kleinerman R, Sankila R, Hammarström L, Robsahm TE, Kääriäinen H, Bregård A, Brøndum-Nielsen K, Yuen J, Tucker M (2005)
    Breast and other cancers in 1445 blood relatives of 75 Nordic patients with ataxia telangiectasia
    Br J Cancer, 93 (2), 260-5
    DOI 10.1038/sj.bjc.6602658, PubMed 15942625
  25. Rødningen OK, Overgaard J, Alsner J, Hastie T, Børresen-Dale AL (2005)
    Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
    Radiother Oncol, 77 (3), 231-40
    DOI 10.1016/j.radonc.2005.09.020, PubMed 16297999
  26. Schaner ME, Davidson B, Skrede M, Reich R, Flørenes VA, Risberg B, Berner A, Goldberg I, Givant-Horwitz V, Tropè CG, Kristensen GB, Nesland JM, Børresen-Dale AL (2005)
    Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients
    Mol Cancer, 4, 26
    DOI 10.1186/1476-4598-4-26, PubMed 16042759
  27. Sharma P, Sahni NS, Tibshirani R, Skaane P, Urdal P, Berghagen H, Jensen M, Kristiansen L, Moen C, Sharma P, Zaka A, Arnes J, Sauer T, Akslen LA, Schlichting E, Børresen-Dale AL, Lönneborg A (2005)
    Early detection of breast cancer based on gene-expression patterns in peripheral blood cells
    Breast Cancer Res, 7 (5), R634-44
    DOI 10.1186/bcr1203, PubMed 16168108
  28. Skotheim RI, Lind GE, Monni O, Nesland JM, Abeler VM, Fosså SD, Duale N, Brunborg G, Kallioniemi O, Andrews PW, Lothe RA (2005)
    Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development
    Cancer Res, 65 (13), 5588-98
    DOI 10.1158/0008-5472.CAN-05-0153, PubMed 15994931
  29. Stormorken AT, Bowitz-Lothe IM, Norèn T, Kure E, Aase S, Wijnen J, Apold J, Heimdal K, Møller P (2005)
    Immunohistochemistry identifies carriers of mismatch repair gene defects causing hereditary nonpolyposis colorectal cancer
    J Clin Oncol, 23 (21), 4705-12
    DOI 10.1200/JCO.2005.05.180, PubMed 16034045
  30. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2005)
    Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
    Methods Mol Biol, 291, 207-16
    PubMed 15502225
  31. Teixeira MR, Heim S (2005)
    Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?
    Semin Cancer Biol, 15 (1), 3-12
    DOI 10.1016/j.semcancer.2004.09.006, PubMed 15613283
  32. Thorstensen L, Lind GE, Løvig T, Diep CB, Meling GI, Rognum TO, Lothe RA (2005)
    Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability
    Neoplasia, 7 (2), 99-108
    DOI 10.1593/neo.04448, PubMed 15802015
  33. Tsalenko A, Sharan R, Edvardsen H, Kristensen V, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2005)
    Analysis of SNP-expression association matrices
    Proc IEEE Comput Syst Bioinform Conf, 135-43
    PubMed 16447971
  34. van der Klift H, Wijnen J, Wagner A, Verkuilen P, Tops C, Otway R, Kohonen-Corish M, Vasen H, Oliani C, Barana D, Moller P, Delozier-Blanchet C, Hutter P, Foulkes W, Lynch H, Burn J, Möslein G, Fodde R (2005)
    Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC)
    Genes Chromosomes Cancer, 44 (2), 123-38
    DOI 10.1002/gcc.20219, PubMed 15942939
  35. von Eyben FE, Jacobsen GK, Skotheim RI (2005)
    Microinvasive germ cell tumor of the testis
    Virchows Arch, 447 (3), 610-25
    DOI 10.1007/s00428-005-1257-8, PubMed 15968545
  36. Wang Y, Helland A, Holm R, Kristensen GB, Børresen-Dale AL (2005)
    PIK3CA mutations in advanced ovarian carcinomas
    Hum Mutat, 25 (3), 322
    DOI 10.1002/humu.9316, PubMed 15712344
  37. Wang Y, Kristensen GB, Helland A, Nesland JM, Børresen-Dale AL, Holm R (2005)
    Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
    Am J Clin Pathol, 124 (3), 392-401
    DOI 10.1309/BL7E-MW66-LQX6-GFRP, PubMed 16191507
  38. Weitzel JN, Robson M, Pasini B, Manoukian S, Stoppa-Lyonnet D, Lynch HT, McLennan J, Foulkes WD, Wagner T, Tung N, Ghadirian P, Olopade O, Isaacs C, Kim-Sing C, Møller P, Neuhausen SL, Metcalfe K, Sun P, Narod SA (2005)
    A comparison of bilateral breast cancers in BRCA carriers
    Cancer Epidemiol Biomarkers Prev, 14 (6), 1534-8
    DOI 10.1158/1055-9965.EPI-05-0070, PubMed 15941968
  39. Wolf M, Edgren H, Muggerud A, Kilpinen S, Huusko P, Sørlie T, Mousses S, Kallioniemi O (2005)
    NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
    Cell Oncol, 27 (3), 169-73
    PubMed 16037637
  40. Aamot HV, Bjørnslett M, Delabie J, Heim S (2005)
    t(14;22)(q32;q11) in non-Hodgkin lymphoma and myeloid leukaemia: molecular cytogenetic investigations
    Br J Haematol, 130 (6), 845-51
    DOI 10.1111/j.1365-2141.2005.05688.x, PubMed 16156854
  41. Aamot HV, Micci F, Holte H, Delabie J, Heim S (2005)
    G-banding and molecular cytogenetic analyses of marginal zone lymphoma
    Br J Haematol, 130 (6), 890-901
    DOI 10.1111/j.1365-2141.2005.05706.x, PubMed 16156859
  42. Aas T, Geisler S, Helle H, Børresen-Dale AL, Lønning PE, Akslen LA (2005)
    Prognostic and predictive value of changes in tumour cell proliferation in locally advanced breast cancer primarily treated with doxorubicin
    Oncol Rep, 13 (3), 525-30
    PubMed 15706428

Publications 2004

  1. Bardi G, Fenger C, Johansson B, Mitelman F, Heim S (2004)
    Tumor karyotype predicts clinical outcome in colorectal cancer patients
    J Clin Oncol, 22 (13), 2623-34
    DOI 10.1200/JCO.2004.11.014, PubMed 15226330
  2. Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Børresen-Dale AL, Concannon P, Thompson WD, WECARE study (2004)
    Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study
    Breast Cancer Res, 6 (3), R199-214
    DOI 10.1186/bcr771, PubMed 15084244
  3. Brandal P, Bjerkehagen B, Heim S (2004)
    Molecular cytogenetic characterization of tenosynovial giant cell tumors
    Neoplasia, 6 (5), 578-83
    DOI 10.1593/neo.04202, PubMed 15548367
  4. Diep CB, Teixeira MR, Thorstensen L, Wiig JN, Eknaes M, Nesland JM, Giercksky KE, Johansson B, Lothe RA (2004)
    Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients
    Mol Cancer, 3, 6
    DOI 10.1186/1476-4598-3-6, PubMed 14977426
  5. Hendriks YM, Wagner A, Morreau H, Menko F, Stormorken A, Quehenberger F, Sandkuijl L, Møller P, Genuardi M, Van Houwelingen H, Tops C, Van Puijenbroek M, Verkuijlen P, Kenter G, Van Mil A, Meijers-Heijboer H, Tan GB, Breuning MH, Fodde R, Wijnen JT, Bröcker-Vriends AH, Vasen H (2004)
    Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance
    Gastroenterology, 127 (1), 17-25
    DOI 10.1053/j.gastro.2004.03.068, PubMed 15236168
  6. Kildal W, Kaern J, Kraggerud SM, Abeler VM, Sudbø J, Tropè CG, Lothe RA, Danielsen HE (2004)
    Evaluation of genomic changes in a large series of malignant ovarian germ cell tumors--relation to clinicopathologic variables
    Cancer Genet Cytogenet, 155 (1), 25-32
    DOI 10.1016/j.cancergencyto.2004.02.010, PubMed 15527899
  7. Kleivi K, Teixeira MR, Eknaes M, Diep CB, Jakobsen KS, Hamelin R, Lothe RA (2004)
    Genome signatures of colon carcinoma cell lines
    Cancer Genet Cytogenet, 155 (2), 119-31
    DOI 10.1016/j.cancergencyto.2004.03.014, PubMed 15571797
  8. Kotar K, Brunet JS, Møller P, Hugel L, Warner E, McLaughlin J, Wong N, Narod SA, Foulkes WD (2004)
    Ratio of female to male offspring of women tested for BRCA1 and BRCA2 mutations
    J Med Genet, 41 (8), e103
    DOI 10.1136/jmg.2004.019687, PubMed 15286163
  9. Lind GE, Thorstensen L, Løvig T, Meling GI, Hamelin R, Rognum TO, Esteller M, Lothe RA (2004)
    A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
    Mol Cancer, 3, 28
    DOI 10.1186/1476-4598-3-28, PubMed 15476557
  10. Lingjaerde OC, Baumbusch LO, Liestøl K, Glad IK, Børresen-Dale AL (2004)
    CGH-Explorer: a program for analysis of array-CGH data
    Bioinformatics, 21 (6), 821-2
    DOI 10.1093/bioinformatics/bti113, PubMed 15531610
  11. Micci F, Teixeira MR, Haugom L, Kristensen G, Abeler VM, Heim S (2004)
    Genomic aberrations in carcinomas of the uterine corpus
    Genes Chromosomes Cancer, 40 (3), 229-46
    DOI 10.1002/gcc.20038, PubMed 15139002
  12. Moger TA, Aalen OO, Heimdal K, Gjessing HK (2004)
    Analysis of testicular cancer data using a frailty model with familial dependence
    Stat Med, 23 (4), 617-32
    DOI 10.1002/sim.1614, PubMed 14755393
  13. Møller P (2004)
    Towards evidence-based management of inherited breast and breast-ovarian cancer
    Hered Cancer Clin Pract, 2 (1), 11-6
    DOI 10.1186/1897-4287-2-1-11, PubMed 20233478
  14. Møller P (2004)
    Costs and benefits of diagnosing familial breast cancer
    Ann Oncol, 15 Suppl 1, I55-I59
    DOI 10.1093/annonc/mdh659, PubMed 15280189
  15. Reichelt JG, Heimdal K, Møller P, Dahl AA (2004)
    BRCA1 testing with definitive results: a prospective study of psychological distress in a large clinic-based sample
    Fam Cancer, 3 (1), 21-8
    DOI 10.1023/B:FAME.0000026820.32469.4a, PubMed 15131402
  16. Richard SM, Bianchi NO, Bianchi MS, Peltomäki P, Lothe RA, Pavicic W (2004)
    Ethnic variation in the prevalence of AZF deletions in testicular cancer
    Mutat Res, 554 (1-2), 45-51
    DOI 10.1016/j.mrfmmm.2004.03.001, PubMed 15450403
  17. Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW et al. (2004)
    Association of metabolic gene polymorphisms with tobacco consumption in healthy controls
    Int J Cancer, 110 (2), 266-70
    DOI 10.1002/ijc.20114, PubMed 15069692
  18. Soucek P, Skjelbred CF, Svendsen M, Kristensen T, Kure EH, Kristensen VN (2004)
    Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
    BMC Biotechnol, 4, 28
    DOI 10.1186/1472-6750-4-28, PubMed 15563733
  19. Stray-Pedersen A, Jónsson T, Heiberg A, Lindman CR, Widing E, Aaberge IS, Borresen-Dale AL, Abrahamsen TG (2004)
    The impact of an early truncating founder ATM mutation on immunoglobulins, specific antibodies and lymphocyte populations in ataxia-telangiectasia patients and their parents
    Clin Exp Immunol, 137 (1), 179-86
    DOI 10.1111/j.1365-2249.2004.02492.x, PubMed 15196260
  20. Staalesen V, Falck J, Geisler S, Bartkova J, Børresen-Dale AL, Lukas J, Lillehaug JR, Bartek J, Lønning PE (2004)
    Alternative splicing and mutation status of CHEK2 in stage III breast cancer
    Oncogene, 23 (52), 8535-44
    DOI 10.1038/sj.onc.1207928, PubMed 15361853
  21. Sørlie T (2004)
    Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
    Eur J Cancer, 40 (18), 2667-75
    DOI 10.1016/j.ejca.2004.08.021, PubMed 15571950
  22. Teixeira MR, Ribeiro FR, Eknaes M, Waehre H, Stenwig AE, Giercksky KE, Heim S, Lothe RA (2004)
    Genomic analysis of prostate carcinoma specimens obtained via ultrasound-guided needle biopsy may be of use in preoperative decision-making
    Cancer, 101 (8), 1786-93
    DOI 10.1002/cncr.20527, PubMed 15386312
  23. Teixeira MR, Ribeiro FR, Torres L, Pandis N, Andersen JA, Lothe RA, Heim S (2004)
    Assessment of clonal relationships in ipsilateral and bilateral multiple breast carcinomas by comparative genomic hybridisation and hierarchical clustering analysis
    Br J Cancer, 91 (4), 775-82
    DOI 10.1038/sj.bjc.6602021, PubMed 15266323
  24. Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM (2004)
    Cell-type-specific responses to chemotherapeutics in breast cancer
    Cancer Res, 64 (12), 4218-26
    DOI 10.1158/0008-5472.CAN-04-0107, PubMed 15205334
  25. Usary J, Llaca V, Karaca G, Presswala S, Karaca M, He X, Langerød A, Kåresen R, Oh DS, Dressler LG, Lønning PE, Strausberg RL, Chanock S, Børresen-Dale AL, Perou CM (2004)
    Mutation of GATA3 in human breast tumors
    Oncogene, 23 (46), 7669-78
    DOI 10.1038/sj.onc.1207966, PubMed 15361840
  26. Wang Y, Helland A, Holm R, Skomedal H, Abeler VM, Danielsen HE, Tropé CG, Børresen-Dale AL, Kristensen GB (2004)
    TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
    Br J Cancer, 90 (3), 678-85
    DOI 10.1038/sj.bjc.6601537, PubMed 14760384
  27. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MM, Olivier M, Skomedal H, Hainaut P, Tropé CG, Abeler VM, Nesland JM, Børresen-Dale AL, Helland A (2004)
    Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
    Hum Mutat, 24 (1), 21-34
    DOI 10.1002/humu.20055, PubMed 15221786
  28. Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, Bukholm IK, Kåresen R, Botstein D, Børresen-Dale AL, Jeffrey SS (2004)
    Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
    Mol Biol Cell, 15 (6), 2523-36
    DOI 10.1091/mbc.e03-11-0786, PubMed 15034139
  29. Zimarina TC, Kristensen VN, Imianitov EN, Bershteĭn LM (2004)
    [Polymorphisms of CYP1B1 and COMT in breast and endometrial cancer]
    Mol Biol (Mosk), 38 (3), 386-93
    PubMed 15285606

Publications 2003

  1. Adeyinka A, Baldetorp B, Mertens F, Olsson H, Johannsson O, Heim S, Pandis N (2003)
    Comparative cytogenetic and DNA flow cytometric analysis of 242 primary breast carcinomas
    Cancer Genet Cytogenet, 147 (1), 62-7
    DOI 10.1016/S0165-4608(03)00190-0, PubMed 14580772
  2. Bernstein JL, Bernstein L, Thompson WD, Lynch CF, Malone KE, Teitelbaum SL, Olsen JH, Anton-Culver H, Boice JD, Rosenstein BS, Børresen-Dale AL, Gatti RA, Concannon P, Haile RW, WECARE Study Collaborative Group (2003)
    ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer
    Br J Cancer, 89 (8), 1513-6
    DOI 10.1038/sj.bjc.6601289, PubMed 14562025
  3. Bernstein JL, Teraoka S, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Diep AT, Jansen L, Atencio DP, Olsen JH, Bernstein L, Teitelbaum SL, Thompson WD, Concannon P, WECARE Study Collaborative Group (2003)
    Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer
    Hum Mutat, 21 (5), 542-50
    DOI 10.1002/humu.10206, PubMed 12673797
  4. Bodd TL, Reichelt J, Heimdal K, Moller P (2003)
    Uptake of BRCA1 genetic testing in adult sisters and daughters of known mutation carriers in Norway
    J Genet Couns, 12 (5), 405-17
    PubMed 14758817
  5. Brandal P, Micci F, Bjerkehagen B, Eknaes M, Larramendy M, Lothe RA, Knuutila S, Heim S (2003)
    Molecular cytogenetic characterization of desmoid tumors
    Cancer Genet Cytogenet, 146 (1), 1-7
    DOI 10.1016/S0165-4608(03)00122-5, PubMed 14499689
  6. Bukholm IR, Husdal A, Nesland JM, Langerød A, Bukholm G (2003)
    Overexpression of cyclin A overrides the effect of p53 alterations in breast cancer patients with long follow-up time
    Breast Cancer Res Treat, 80 (2), 199-206
    DOI 10.1023/A:1024527220362, PubMed 12908823
  7. Børresen-Dale AL (2003)
    Genetic profiling of breast cancer: from molecular portraits to clinical utility
    Int J Biol Markers, 18 (1), 54-6
    PubMed 12699064
  8. Børresen-Dale AL (2003)
    TP53 and breast cancer
    Hum Mutat, 21 (3), 292-300
    DOI 10.1002/humu.10174, PubMed 12619115
  9. Diep CB, Parada LA, Teixeira MR, Eknaes M, Nesland JM, Johansson B, Lothe RA (2003)
    Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis
    Genes Chromosomes Cancer, 36 (2), 189-97
    DOI 10.1002/gcc.10162, PubMed 12508247
  10. Diep CB, Thorstensen L, Meling GI, Skovlund E, Rognum TO, Lothe RA (2003)
    Genetic tumor markers with prognostic impact in Dukes' stages B and C colorectal cancer patients
    J Clin Oncol, 21 (5), 820-9
    DOI 10.1200/JCO.2003.05.190, PubMed 12610180
  11. Fadl-Elmula I, Gorunova L, Mandahl N, Heim S (2003)
    Chromosomal abnormalities in inflammatory pseudotumor of the urinary bladder
    Cancer Genet Cytogenet, 143 (2), 169-71
    DOI 10.1016/S0165-4608(02)00846-4, PubMed 12781452
  12. Geisler S, Børresen-Dale AL, Johnsen H, Aas T, Geisler J, Akslen LA, Anker G, Lønning PE (2003)
    TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer
    Clin Cancer Res, 9 (15), 5582-8
    PubMed 14654539
  13. Haslekås C, Grini PE, Nordgard SH, Thorstensen T, Viken MK, Nygaard V, Aalen RB (2003)
    ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress
    Plant Mol Biol, 53 (3), 313-26
    DOI 10.1023/B:PLAN.0000006937.21343.2a, PubMed 14750521
  14. Haslekås C, Viken MK, Grini PE, Nygaard V, Nordgard SH, Meza TJ, Aalen RB (2003)
    Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress
    Plant Physiol, 133 (3), 1148-57
    DOI 10.1104/pp.103.025916, PubMed 14526116
  15. Heimdal K, Maehle L, Apold J, Pedersen JC, Møller P (2003)
    The Norwegian founder mutations in BRCA1: high penetrance confirmed in an incident cancer series and differences observed in the risk of ovarian cancer
    Eur J Cancer, 39 (15), 2205-13
    DOI 10.1016/S0959-8049(03)00548-3, PubMed 14522380
  16. Henriksen J, Aagesen TH, Maelandsmo GM, Lothe RA, Myklebost O, Forus A (2003)
    Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
    Oncogene, 22 (34), 5358-61
    DOI 10.1038/sj.onc.1206671, PubMed 12917637
  17. Ioannidis P, Mahaira L, Papadopoulou A, Teixeira MR, Heim S, Andersen JA, Evangelou E, Dafni U, Pandis N, Trangas T (2003)
    8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas
    Int J Cancer, 104 (1), 54-9
    DOI 10.1002/ijc.10794, PubMed 12532419
  18. Ioannidis P, Mahaira L, Papadopoulou A, Teixeira MR, Heim S, Andersen JA, Evangelou E, Dafni U, Pandis N, Trangas T (2003)
    CRD-BP: a c-Myc mRNA stabilizing protein with an oncofetal pattern of expression
    Anticancer Res, 23 (3A), 2179-83
    PubMed 12894594
  19. Kildal W, Kraggerud SM, Abeler VM, Heim S, Tropé CG, Kristensen GB, Risberg B, Lothe RA, Danielsen HE (2003)
    Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
    Hum Pathol, 34 (9), 946-9
    DOI 10.1016/S0046-8177(03)00345-9, PubMed 14562293
  20. Kraggerud SM, Lee MP, Skotheim RI, Stenwig AE, Fosså SD, Feinberg AP, Lothe RA (2003)
    Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors
    Cancer Genet Cytogenet, 147 (1), 1-8
    DOI 10.1016/S0165-4608(03)00160-2, PubMed 14580764
  21. Kristensen V, Aven T (2003)
    How to approach modelling in a risk analysis
    SAFETY AND RELIABILITY, VOLS 1 AND 2, 969-976
  22. Kristiansen M, Helland A, Kristensen GB, Olsen AO, Lønning PE, Børresen-Dale AL, Ørstavik KH (2003)
    X chromosome inactivation in cervical cancer patients
    Cancer Genet Cytogenet, 146 (1), 73-6
    DOI 10.1016/S0165-4608(03)00152-3, PubMed 14499700
  23. Langerød A, Strømberg M, Chin K, Kristensen VN, Børresen-Dale AL (2003)
    BUB1 infrequently mutated in human breast carcinomas
    Hum Mutat, 22 (5), 420
    DOI 10.1002/humu.9194, PubMed 14517964
  24. Løvig T, Thorstensen L, Hofstad B, Andersen SN, Clausen OP, Vatn M, Lothe RA, Rognum TO (2003)
    Genetic and protein markers related to in situ growth and multiplicity in small sporadic colorectal adenomas
    Scand J Gastroenterol, 38 (3), 298-306
    DOI 10.1080/00365520310000618, PubMed 12737446
  25. Micci F, Teixeira MR, Scheistrøen M, Abeler VM, Heim S (2003)
    Cytogenetic characterization of tumors of the vulva and vagina
    Genes Chromosomes Cancer, 38 (2), 137-48
    DOI 10.1002/gcc.10263, PubMed 12939741
  26. Micci F, Walter CU, Teixeira MR, Panagopoulos I, Bjerkehagen B, Saeter G, Heim S (2003)
    Cytogenetic and molecular genetic analyses of endometrial stromal sarcoma: nonrandom involvement of chromosome arms 6p and 7p and confirmation of JAZF1/JJAZ1 gene fusion in t(7;17)
    Cancer Genet Cytogenet, 144 (2), 119-24
    DOI 10.1016/S0165-4608(03)00025-6, PubMed 12850374
  27. Normann AP, Egeland T, Madshus IH, Heim S, Tjønnfjord GE (2003)
    CD7 expression by CD34+ cells in CML patients, of prognostic significance?
    Eur J Haematol, 71 (4), 266-75
    DOI 10.1034/j.1600-0609.2003.00133.x, PubMed 12950236
  28. Os I, Høieggen A, Larsen A, Sandset PM, Djurovic S, Berg K, Os A, Birkeland K, Westheim A (2003)
    Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function
    J Intern Med, 253 (2), 232-9
    DOI 10.1046/j.1365-2796.2003.01110.x, PubMed 12542565
  29. Pan-Hammarström Q, Dai S, Zhao Y, van Dijk-Härd IF, Gatti RA, Børresen-Dale AL, Hammarström L (2003)
    ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region
    J Immunol, 170 (7), 3707-16
    DOI 10.4049/jimmunol.170.7.3707, PubMed 12646636
  30. Papadopoulou A, Trangas T, Teixeira MR, Heim S, Dimitriadis E, Tsarouha H, Andersen JA, Evangelou E, Ioannidis P, Agnantis NJ, Pandis N (2003)
    Telomerase activity and genetic alterations in primary breast carcinomas
    Neoplasia, 5 (2), 170-8
    DOI 10.1016/S1476-5586(03)80009-X, PubMed 12659690
  31. Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, Fero MJ, Kristensen GB, Borresen-Dale AL, Hastie T, Tibshirani R, van de Rijn M, Teng NN, Longacre TA, Botstein D, Brown PO et al. (2003)
    Gene expression patterns in ovarian carcinomas
    Mol Biol Cell, 14 (11), 4376-86
    DOI 10.1091/mbc.e03-05-0279, PubMed 12960427
  32. Skotheim RI, Abeler VM, Nesland JM, Fosså SD, Holm R, Wagner U, Flørenes VA, Aass N, Kallioniemi OP, Lothe RA (2003)
    Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarrays
    Neoplasia, 5 (5), 397-404
    DOI 10.1016/S1476-5586(03)80042-8, PubMed 14670177
  33. Skotheim RI, Kallioniemi A, Bjerkhagen B, Mertens F, Brekke HR, Monni O, Mousses S, Mandahl N, Soeter G, Nesland JM, Smeland S, Kallioniemi OP, Lothe RA (2003)
    Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome
    J Clin Oncol, 21 (24), 4586-91
    DOI 10.1200/JCO.2003.07.067, PubMed 14673046
  34. Skotheim RI, Korkmaz KS, Klokk TI, Abeler VM, Korkmaz CG, Nesland JM, Fosså SD, Lothe RA, Saatcioglu F (2003)
    NKX3.1 expression is lost in testicular germ cell tumors
    Am J Pathol, 163 (6), 2149-54
    DOI 10.1016/S0002-9440(10)63571-7, PubMed 14633588
  35. Skotheim RI, Lothe RA (2003)
    The testicular germ cell tumour genome
    APMIS, 111 (1), 136-50; discussion 50-1
    DOI 10.1034/j.1600-0463.2003.11101181.x, PubMed 12752254
  36. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D (2003)
    Repeated observation of breast tumor subtypes in independent gene expression data sets
    Proc Natl Acad Sci U S A, 100 (14), 8418-23
    DOI 10.1073/pnas.0932692100, PubMed 12829800
  37. Soucek P, Gut I, Trneny M, Skovlund E, Grenaker Alnaes G, Kristensen T, Børresen-Dale AL, Kristensen VN (2003)
    Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin
    Eur J Hum Genet, 11 (5), 416-9
    DOI 10.1038/sj.ejhg.5200972, PubMed 12734548
  38. Stacy JE, Kausmally L, Simonsen B, Nordgard SH, Alsøe L, Michaelsen TE, Brekke OH (2003)
    Direct isolation of recombinant human antibodies against group B Neisseria meningitidis from scFv expression libraries
    J Immunol Methods, 283 (1-2), 247-59
    DOI 10.1016/j.jim.2003.09.015, PubMed 14659916
  39. Stepensky D, Kleinberg L, Hoffman A (2003)
    Bone as an effect compartment : models for uptake and release of drugs
    Clin Pharmacokinet, 42 (10), 863-81
    DOI 10.2165/00003088-200342100-00001, PubMed 12885262
  40. Stormorken AT, Müller W, Lindblom A, Heimdal K, Aase S, Lothe IM, Norèn T, Wijnen JT, Möslein G, Møller P (2003)
    The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours
    Fam Cancer, 2 (1), 9-13
    PubMed 14574162
  41. Teixeira MR, Pandis N, Heim S (2003)
    Multicentric mammary carcinoma: evidence of monoclonal proliferation
    Cancer, 97 (3), 715-7; author reply 717
    DOI 10.1002/cncr.11109, PubMed 12548617
  42. Yoshimura N, Harada N, Bukholm I, Kåresen R, Børresen-Dale AL, Kristensen VN (2003)
    Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer
    Breast Cancer Res, 6 (2), R46-55
    DOI 10.1186/bcr746, PubMed 14979917
  43. Aas T, Geisler S, Eide GE, Haugen DF, Varhaug JE, Bassoe AM, Thorsen T, Berntsen H, Borresen-Dale AL, Akslen LA, Lonning PE (2003)
    Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy
    Eur. J. Cancer, 39 (4), PII S0959-8049(02)00732-3-446
  44. Aas T, Geisler S, Eide GE, Haugen DF, Varhaug JE, Bassøe AM, Thorsen T, Berntsen H, Børresen-Dale AL, Akslen LA, Lønning PE (2003)
    Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy
    Eur J Cancer, 39 (4), 438-46
    PubMed 12751373

Publications 2002

  1. Allinen M, Launonen V, Laake K, Jansen L, Huusko P, Kääriäinen H, Børresen-Dale AL, Winqvist R (2002)
    ATM mutations in Finnish breast cancer patients
    J Med Genet, 39 (3), 192-6
    DOI 10.1136/jmg.39.3.192, PubMed 11897822
  2. Bernstein JL, Seminara D, Børresen-Dale AL (2002)
    Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002
    Breast Cancer Res, 4 (6), 249-52
    PubMed 12473172
  3. Børresen AL (2002)
    Mismatch detection using heteroduplex analysis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.3
    DOI 10.1002/0471142905.hg0703s33, PubMed 18428333
  4. Fadl-Elmula I, Kytola S, Leithy ME, Abdel-Hameed M, Mandahl N, Elagib A, Ibrahim M, Larsson C, Heim S (2002)
    Chromosomal aberrations in benign and malignant bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
    BMC Cancer, 2, 5
    DOI 10.1186/1471-2407-2-5, PubMed 11914143
  5. Ikonomou IM, Nesland JM, Schjølseth SA, Heim S, Delabie J (2002)
    Mantle cell lymphoma with Homer-Wright rosettes