Silje Alvestad

  • MD, PhD, Senior researcher (post.doc)
 

Publications 2024

Battino D, Tomson T, Bonizzoni E, Craig J, Perucca E, Sabers A, Thomas S, Alvestad S, Perucca P, Vajda F, EURAP Collaborators (2024)
Risk of Major Congenital Malformations and Exposure to Antiseizure Medication Monotherapy
JAMA Neurol, 81 (5), 481-489
DOI 10.1001/jamaneurol.2024.0258, PubMed 38497990

Christensen J, Zoega H, Leinonen MK, Gilhus NE, Gissler M, Igland J, Sun Y, Tomson T, Alvestad S, Bjørk MH, Dreier JW (2024)
Prenatal exposure to antiseizure medications and fetal growth: a population-based cohort study from the Nordic countries
Lancet Reg Health Eur, 38, 100849
DOI 10.1016/j.lanepe.2024.100849, PubMed 38476755

Leinonen MK, Igland J, Dreier JW, Alvestad S, Cohen JM, Gilhus NE, Gissler M, Sun Y, Tomson T, Zoega H, Vegrim HM, Christensen J, Bjørk MH (2024)
Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population-based study from Nordic universal health care systems
Epilepsia (in press)
DOI 10.1111/epi.18022, PubMed 38804650

Vegrim HM, Dreier JW, Igland J, Gilhus NE, Alvestad S, Gissler M, Leinonen MK, Sun Y, Zoega H, Christensen J, Bjørk MH, Tomson T (2024)
Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication
Epilepsia, 65 (6), 1698-1708
DOI 10.1111/epi.17969, PubMed 38554037

Publications 2023

Bjørk MH, Tomson T, Dreier JW, Alvestad S, Gilhus NE, Gissler M, Igland J, Leinonen MK, Sun Y, Vegrim HM, Zoega H, Christensen J (2023)
High-dose folic acid and cancer risk; unjustified concerns by von Wrede and colleagues regarding our paper
Epilepsia, 64 (9), 2244-2248
DOI 10.1111/epi.17717, PubMed 37452793

Cohen JM, Alvestad S, Suarez EA, Schaffer A, Selmer RM, Havard A, Bateman BT, Cesta CE, Zoega H, Odsbu I, Huybrechts KF, Kjerpeseth LJ, Straub L, Leinonen MK, Bjørk MH, Nørgaard M, Gissler M, Ulrichsen SP, Hernandez-Diaz S, Tomson T, Furu K (2023)
Comparative Risk of Major Congenital Malformations With Antiseizure Medication Combinations vs Valproate Monotherapy in Pregnancy
Neurology, 102 (2), e207996
DOI 10.1212/WNL.0000000000207996, PubMed 38165339

Dreier JW, Bjørk MH, Alvestad S, Gissler M, Igland J, Leinonen MK, Sun Y, Zoega H, Cohen JM, Furu K, Tomson T, Christensen J (2023)
Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders
JAMA Neurol, 80 (6), 568-577
DOI 10.1001/jamaneurol.2023.0674, PubMed 37067807

Dreier JW, Bjørk MH, Alvestad S, Gissler M, Igland J, Leinonen MK, Sun Y, Zoega H, Cohen JM, Furu K, Tomson T, Christensen J (2023)
In reply: Why big data carries big potential rather than big trouble
Seizure, 111, 106-108
DOI 10.1016/j.seizure.2023.08.007, PubMed 37597398

Karadag N, Shadrin AA, O'Connell KS, Hindley GFL, Rahman Z, Parker N, Bahrami S, Fominykh V, Cheng W, Holen B, Alvestad S, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2023)
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
Brain, 146 (8), 3392-3403
DOI 10.1093/brain/awad038, PubMed 36757824

Publications 2022

Alvestad S, Husebye ESN, Christensen J, Dreier JW, Sun Y, Igland J, Leinonen MK, Gissler M, Gilhus NE, Tomson T, Bjørk M (2022)
Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy: A Prospective Cohort Study
Neurology, 99 (6), e605-e615
DOI 10.1212/WNL.0000000000200669, PubMed 35577577

Bjørk MH, Zoega H, Leinonen MK, Cohen JM, Dreier JW, Furu K, Gilhus NE, Gissler M, Hálfdánarson Ó, Igland J, Sun Y, Tomson T, Alvestad S, Christensen J (2022)
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability
JAMA Neurol, 79 (7), 672-681
DOI 10.1001/jamaneurol.2022.1269, PubMed 35639399

Cohen JM, Alvestad S, Cesta CE, Bjørk MH, Leinonen MK, Nørgaard M, Einarsdóttir K, Engeland A, Gissler M, Karlstad Ø, Klungsøyr K, Odsbu I, Reutfors J, Selmer RM, Tomson T, Ulrichsen SP, Zoega H, Furu K (2022)
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations
Ann Neurol, 93 (3), 551-562
DOI 10.1002/ana.26561, PubMed 36433783

González A, Haugaa KH, Brekke PH, Hopp E, Ørn S, Alvestad S, Taubøll E, Aurlien D (2022)
Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures
Case Rep Neurol, 14 (1), 88-97
DOI 10.1159/000522237, PubMed 35431877

Vegrim HM, Dreier JW, Alvestad S, Gilhus NE, Gissler M, Igland J, Leinonen MK, Tomson T, Sun Y, Zoega H, Christensen J, Bjørk MH (2022)
Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy
JAMA Neurol, 79 (11), 1130-1138
DOI 10.1001/jamaneurol.2022.2977, PubMed 36156660

Publications 2020

Zaidan S, Nakken KO, Lillestølen KM, Alvestad S, Lossius MI (2020)
[Assisted reproductive treatment in women with epilepsy]
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0253, PubMed 31948216

Zaidan S, Nakken KO, Lillestølen KM, Alvestad S, Lossius MI (2020)
[Correction: Assisted reproductive technology among women with epilepsy]
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.20.0063, PubMed 32105046

Publications 2019

Alvestad S (2019)
Valproate remains important for women with generalized epilepsy
Tidsskr. Nor. Laegeforen., 139 (7), 585

Alvestad S, Bjørnvold M, Molteberg E, Lossius M, Landmark CJ (2019)
[Continued importance of valproate for women with generalised epilepsy]
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0220, PubMed 30969058

Publications 2013

Alvestad S, Hammer J, Hoddevik EH, Skare Ø, Sonnewald U, Amiry-Moghaddam M, Ottersen OP (2013)
Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy
Epilepsy Res, 105 (1-2), 30-41
DOI 10.1016/j.eplepsyres.2013.01.006, PubMed 23357720

Publications 2011

Alvestad S, Hammer J, Qu H, Håberg A, Ottersen OP, Sonnewald U (2011)
Reduced astrocytic contribution to the turnover of glutamate, glutamine, and GABA characterizes the latent phase in the kainate model of temporal lobe epilepsy
J Cereb Blood Flow Metab, 31 (8), 1675-86
DOI 10.1038/jcbfm.2011.36, PubMed 21522161

Shirzadi M, Alvestad S, Hovdal H, Espeset K, Lydersen S, Brodtkorb E (2011)
Comparison of carbamazepine rash in multiple sclerosis and epilepsy
Acta Neurol Scand, 125 (1), 60-3
DOI 10.1111/j.1600-0404.2011.01553.x, PubMed 21668415

Publications 2008

Alvestad S, Lydersen S, Brodtkorb E (2008)
Cross-reactivity pattern of rash from current aromatic antiepileptic drugs
Epilepsy Res, 80 (2-3), 194-200
DOI 10.1016/j.eplepsyres.2008.04.003, PubMed 18490142

Hammer J, Alvestad S, Osen KK, Skare Ø, Sonnewald U, Ottersen OP (2008)
Expression of glutamine synthetase and glutamate dehydrogenase in the latent phase and chronic phase in the kainate model of temporal lobe epilepsy
Glia, 56 (8), 856-68
DOI 10.1002/glia.20659, PubMed 18381650

Publications 2007

Alvestad S, Goa PE, Qu H, Risa Ø, Brekken C, Sonnewald U, Haraldseth O, Hammer J, Ottersen OP, Håberg A (2007)
In vivo mapping of temporospatial changes in manganese enhancement in rat brain during epileptogenesis
Neuroimage, 38 (1), 57-66
DOI 10.1016/j.neuroimage.2007.07.027, PubMed 17822925

Alvestad S, Hammer J, Eyjolfsson E, Qu H, Ottersen OP, Sonnewald U (2007)
Limbic structures show altered glial-neuronal metabolism in the chronic phase of kainate induced epilepsy
Neurochem Res, 33 (2), 257-66
DOI 10.1007/s11064-007-9435-5, PubMed 17710539

Alvestad S, Lydersen S, Brodtkorb E (2007)
Rash from antiepileptic drugs: influence by gender, age, and learning disability
Epilepsia, 48 (7), 1360-5
DOI 10.1111/j.1528-1167.2007.01109.x, PubMed 17484761

Kondziella D, Alvestad S, Vaaler A, Sonnewald U (2007)
Which clinical and experimental data link temporal lobe epilepsy with depression?
J Neurochem, 103 (6), 2136-52
DOI 10.1111/j.1471-4159.2007.04926.x, PubMed 17887964

Publications 2005

Hammer J, Alvestad S, Qu H, Risa Ø, Osen K, Sonnewald U (2005)
Glial-neuronal interactions during the latent and chronicperiods following kainate induced seizures in rats
[Raven Press], [New York], Bl. 109
BIBSYS 061116866

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