Publications

Publications 2019

Bains SJ, Niehusmann PF, Meling TR, Saxhaug C, Züchner M, Brandal P (2019)
Disseminated central nervous system hemangioblastoma in a patient with no clinical or genetic evidence of von Hippel-Lindau disease-a case report and literature review
Acta Neurochir (Wien), 161 (2), 343-349
DOI 10.1007/s00701-019-03800-z, PubMed 30652202

Bakke KM, Grøvik E, Meltzer S, Negård A, Holmedal SH, Mikalsen LTG, Lyckander LG, Ree AH, Gjesdal KI, Redalen KR, Bjørnerud A (2019)
Comparison of Intravoxel incoherent motion imaging and multiecho dynamic contrast-based MRI in rectal cancer
J Magn Reson Imaging (in press)
DOI 10.1002/jmri.26740, PubMed 30945379

Grøvik E, Yi D, Iv M, Tong E, Rubin D, Zaharchuk G (2019)
Deep learning enables automatic detection and segmentation of brain metastases on multisequence MRI
J Magn Reson Imaging (in press)
DOI 10.1002/jmri.26766, PubMed 31050074

Latysheva A, Emblem KE, Brandal P, Vik-Mo EO, Pahnke J, Røysland K, Hald JK, Server A (2019)
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach
Neuroradiology, 61 (5), 545-555
DOI 10.1007/s00234-019-02173-5, PubMed 30712139

Lundar T, Due-Tønnessen BJ, Frič R, Brandal P, Stensvold E, Due-Tønnessen P (2019)
Adult outcome after neurosurgical treatment of brain tumours in the first year of life: long-term follow-up of a single consecutive institutional series of 34 patients
Acta Neurochir (Wien) (in press)
DOI 10.1007/s00701-019-04014-z, PubMed 31309304

Lundar T, Due-Tønnessen BJ, Frič R, Krossnes B, Brandal P, Stensvold E, Due-Tønnessen P (2019)
Neurosurgical treatment of pediatric pleomorphic xanthoastrocytomas: long-term follow-up of a single-institution, consecutive series of 12 patients
J Neurosurg Pediatr, 23 (4), 512-516
DOI 10.3171/2018.11.PEDS18449, PubMed 30738389

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER (2019)
Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI
Sci Rep, 9 (1), 8721
DOI 10.1038/s41598-019-44365-2, PubMed 31197238

Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK (2019)
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium
Nat Biomed Eng, 3 (3), 230-245
DOI 10.1038/s41551-018-0334-7, PubMed 30948807

Stensvold E, Myklebust TÅ, Cappelen J, Due-Tønnessen BJ, Due-Tønnessen P, Kepka A, Johannesen TB, Krossnes B, Lundar T, Maric S, Miletic H, Moholdt V, Myrmel KS, Nordberg T, Rydland J, Stokland T, Solem K, Solheim O, Torsvik I, Wikran GC, Zeller B, Wesenberg F, Bechensteen AG, Brandal P (2019)
Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival
Pediatr Blood Cancer, e27910
DOI 10.1002/pbc.27910, PubMed 31264356

Publications 2018

Angeli S, Emblem KE, Due-Tonnessen P, Stylianopoulos T (2018)
Towards patient-specific modeling of brain tumor growth and formation of secondary nodes guided by DTI-MRI
Neuroimage Clin, 20, 664-673
DOI 10.1016/j.nicl.2018.08.032, PubMed 30211003

Digernes I, Grøvik E, Nilsen LB, Saxhaug C, Geier O, Reitan E, Sætre DO, Breivik B, Reese T, Jacobsen KD, Helland Å, Emblem KE (2018)
Brain metastases with poor vascular function are susceptible to pseudoprogression after stereotactic radiation surgery
Adv Radiat Oncol, 3 (4), 559-567
DOI 10.1016/j.adro.2018.05.005, PubMed 30370356

Eide PK, Vatnehol SAS, Emblem KE, Ringstad G (2018)
Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes
Sci Rep, 8 (1), 7194
DOI 10.1038/s41598-018-25666-4, PubMed 29740121

Krogsrud SK, Fjell AM, Tamnes CK, Grydeland H, Due-Tønnessen P, Bjørnerud A, Sampaio-Baptista C, Andersson J, Johansen-Berg H, Walhovd KB (2018)
Development of white matter microstructure in relation to verbal and visuospatial working memory-A longitudinal study
PLoS One, 13 (4), e0195540
DOI 10.1371/journal.pone.0195540, PubMed 29689058

Lundar T, Due-Tønnessen BJ, Fric R, Due-Tønnessen P (2018)
Postoperative radiotherapy for pediatric brain tumor: a lesson learned from treatment of a 5-year-old girl for posterior fossa astrocytoma (WHO1) in 1967
Acta Neurochir (Wien), 160 (10), 2065-2066
DOI 10.1007/s00701-018-3636-3, PubMed 30046877

Lundar T, Due-Tønnessen BJ, Fric R, Egge A, Krossnes B, Due-Tønnessen P, Stensvold E, Brandal P (2018)
Neurosurgical treatment of gangliogliomas in children and adolescents: long-term follow-up of a single-institution series of 32 patients
Acta Neurochir (Wien), 160 (6), 1207-1214
DOI 10.1007/s00701-018-3550-8, PubMed 29680921

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER (2018)
Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI
Sci Rep, 8 (1), 17062
DOI 10.1038/s41598-018-34820-x, PubMed 30459364

Meling TR, Latysheva A, Da Broi M, Jahr G, Holte H, Beiske K, Emblem KE (2018)
Is deep brain involvement in intracranial primary central nervous system lymphoma of importance for penetration of chemotherapeutic agents?
Neuroradiology, 60 (7), 703-713
DOI 10.1007/s00234-018-2038-9, PubMed 29804159

Nygaard E, Slinning K, Moe V, Due-Tønnessen P, Fjell A, Walhovd KB (2018)
Neuroanatomical characteristics of youths with prenatal opioid and poly-drug exposure
Neurotoxicol Teratol, 68, 13-26
DOI 10.1016/j.ntt.2018.04.004, PubMed 29679636

Ringstad G, Valnes LM, Dale AM, Pripp AH, Vatnehol SS, Emblem KE, Mardal KA, Eide PK (2018)
Brain-wide glymphatic enhancement and clearance in humans assessed with MRI
JCI Insight, 3 (13)
DOI 10.1172/jci.insight.121537, PubMed 29997300

Publications 2017

Andronesi OC, Esmaeili M, Borra RJH, Emblem K, Gerstner ER, Pinho MC, Plotkin SR, Chi AS, Eichler AF, Dietrich J, Ivy SP, Wen PY, Duda DG, Jain R, Rosen BR, Sorensen GA, Batchelor TT (2017)
Early changes in glioblastoma metabolism measured by MR spectroscopic imaging during combination of anti-angiogenic cediranib and chemoradiation therapy are associated with survival
NPJ Precis Oncol, 1
DOI 10.1038/s41698-017-0020-3, PubMed 29202103

Bjørnerud A, Vatnehol SAS, Larsson C, Due-Tønnessen P, Hol PK, Groote IR (2017)
Signal Enhancement of the Dentate Nucleus at Unenhanced MR Imaging after Very High Cumulative Doses of the Macrocyclic Gadolinium-based Contrast Agent Gadobutrol: An Observational Study
Radiology, 285 (2), 434-444
DOI 10.1148/radiol.2017170391, PubMed 28885891

Digernes I, Bjørnerud A, Vatnehol SAS, Løvland G, Courivaud F, Vik-Mo E, Meling TR, Emblem KE (2017)
A theoretical framework for determining cerebral vascular function and heterogeneity from dynamic susceptibility contrast MRI
J Cereb Blood Flow Metab, 37 (6), 2237-2248
DOI 10.1177/0271678X17694187, PubMed 28273722

Ringstad G, Lindstrøm EK, Vatnehol SAS, Mardal KA, Emblem KE, Eide PK (2017)
Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging
PLoS One, 12 (11), e0188896
DOI 10.1371/journal.pone.0188896, PubMed 29190788

Stensvold E, Krossnes BK, Lundar T, Due-Tønnessen BJ, Frič R, Due-Tønnessen P, Bechensteen AG, Myklebust TÅ, Johannesen TB, Brandal P (2017)
Outcome for children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor (CNS-PNET) - a retrospective analysis spanning 40 years of treatment
Acta Oncol, 56 (5), 698-705
DOI 10.1080/0284186X.2017.1301679, PubMed 28325133

Publications 2016

Bjørnebekk A, Walhovd KB, Jørstad ML, Due-Tønnessen P, Hullstein IR, Fjell AM (2016)
Structural Brain Imaging of Long-Term Anabolic-Androgenic Steroid Users and Nonusing Weightlifters
Biol Psychiatry, 82 (4), 294-302
DOI 10.1016/j.biopsych.2016.06.017, PubMed 27616036

Emblem KE, Jain RK (2016)
Improving treatment of liver metastases by targeting nonangiogenic mechanisms
Nat Med, 22 (11), 1209-1210
DOI 10.1038/nm.4228, PubMed 27824818

Grøvik E, Redalen KR, Storås TH, Negård A, Holmedal SH, Ree AH, Meltzer S, Bjørnerud A, Gjesdal KI (2016)
Dynamic multi-echo DCE- and DSC-MRI in rectal cancer: Low primary tumor K^trans and ΔR2* peak are significantly associated with lymph node metastasis
J Magn Reson Imaging, 46 (1), 194-206
DOI 10.1002/jmri.25566, PubMed 28001320

Kalpathy-Cramer J, Chandra V, Da X, Ou Y, Emblem KE, Muzikansky A, Cai X, Douw L, Evans JG, Dietrich J, Chi AS, Wen PY, Stufflebeam S, Rosen B, Duda DG, Jain RK, Batchelor TT, Gerstner ER (2016)
Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma
J Neurooncol, 131 (3), 603-610
DOI 10.1007/s11060-016-2332-5, PubMed 27853960

Varghese M, Nymoen HG, Saxhaug C, Krossnes B, Abdol Mohieb Hosainey S, Meling TR, Brandal P (2016)
Symptomatic spinal metastasis from intracranial glioblastoma multiforme - Two illustrative cases and a review of the literature
Acta Oncol, 55 (9-10), 1236-1238
DOI 10.3109/0284186X.2016.1161824, PubMed 27174685

Walhovd KB, Krogsrud SK, Amlien IK, Bartsch H, Bjørnerud A, Due-Tønnessen P, Grydeland H, Hagler DJ, Håberg AK, Kremen WS, Ferschmann L, Nyberg L, Panizzon MS, Rohani DA, Skranes J, Storsve AB, Sølsnes AE, Tamnes CK, Thompson WK, Reuter C, Dale AM, Fjell AM (2016)
Neurodevelopmental origins of lifespan changes in brain and cognition
Proc Natl Acad Sci U S A, 113 (33), 9357-62
DOI 10.1073/pnas.1524259113, PubMed 27432992

Publications 2015

Almaas AN, Tamnes CK, Nakstad B, Henriksen C, Walhovd KB, Fjell AM, Due-Tønnessen P, Drevon CA, Iversen PO (2015)
Long-chain polyunsaturated fatty acids and cognition in VLBW infants at 8 years: an RCT
Pediatrics, 135 (6), 972-80
DOI 10.1542/peds.2014-4094, PubMed 25986018

Due-Tønnessen BJ, Egge A, Lundar T, Krossnes B, Stensvold E, Due-Tønnessen P, Brandal P (2015)
Posterior fossa ependymoblastoma diagnosed in the second month of life: uneventful 12 years survival after gross total resection followed by chemotherapy
Springerplus, 4, 389
DOI 10.1186/s40064-015-1178-1, PubMed 26251773

Fjell AM, Grydeland H, Krogsrud SK, Amlien I, Rohani DA, Ferschmann L, Storsve AB, Tamnes CK, Sala-Llonch R, Due-Tønnessen P, Bjørnerud A, Sølsnes AE, Håberg AK, Skranes J, Bartsch H, Chen CH, Thompson WK, Panizzon MS, Kremen WS, Dale AM, Walhovd KB (2015)
Development and aging of cortical thickness correspond to genetic organization patterns
Proc Natl Acad Sci U S A, 112 (50), 15462-7
DOI 10.1073/pnas.1508831112, PubMed 26575625

Gerstner ER, Emblem KE, Sorensen GA (2015)
Vascular Magnetic Resonance Imaging in Brain Tumors During Antiangiogenic Therapy--Are We There Yet?
Cancer J, 21 (4), 337-42
DOI 10.1097/PPO.0000000000000128, PubMed 26222087

Heck A, Emblem KE, Casar-Borota O, Bollerslev J, Ringstad G (2015)
Quantitative analyses of T2-weighted MRI as a potential marker for response to somatostatin analogs in newly diagnosed acromegaly
Endocrine, 52 (2), 333-43
DOI 10.1007/s12020-015-0766-8, PubMed 26475495

Heck A, Emblem KE, Casar-Borota O, Ringstad G, Bollerslev J (2015)
MRI T2 characteristics in somatotroph adenomas following somatostatin analog treatment in acromegaly
Endocrine, 53 (1), 327-30
DOI 10.1007/s12020-015-0816-2, PubMed 26615593

Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM (2015)
Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients
Transl Oncol, 8 (3), 137-46
DOI 10.1016/j.tranon.2015.03.002, PubMed 26055170

Juuhl-Langseth M, Hartberg CB, Holmén A, Thormodsen R, Groote IR, Rimol LM, Emblem KE, Agartz I, Rund BR (2015)
Impaired Verbal Learning Is Associated with Larger Caudate Volumes in Early Onset Schizophrenia Spectrum Disorders
PLoS One, 10 (7), e0130435
DOI 10.1371/journal.pone.0130435, PubMed 26230626

Krogsrud SK, Fjell AM, Tamnes CK, Grydeland H, Mork L, Due-Tønnessen P, Bjørnerud A, Sampaio-Baptista C, Andersson J, Johansen-Berg H, Walhovd KB (2015)
Changes in white matter microstructure in the developing brain--A longitudinal diffusion tensor imaging study of children from 4 to 11years of age
Neuroimage, 124 (Pt A), 473-486
DOI 10.1016/j.neuroimage.2015.09.017, PubMed 26375208

Lu-Emerson C, Duda DG, Emblem KE, Taylor JW, Gerstner ER, Loeffler JS, Batchelor TT, Jain RK (2015)
Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma
J Clin Oncol, 33 (10), 1197-213
DOI 10.1200/JCO.2014.55.9575, PubMed 25713439

Lundar T, Due-Tønnessen BJ, Egge A, Krossnes B, Stensvold E, Due-Tønnessen P, Brandal P (2015)
Neurosurgical treatment of brain tumors in the first 6 months of life: long-term follow-up of a single consecutive institutional series of 30 patients
Childs Nerv Syst, 31 (12), 2283-90
DOI 10.1007/s00381-015-2792-5, PubMed 26174616

Lundar T, Due-Tønnessen BJ, Krossnes B, Due-Tønnessen P, Brandal P (2015)
Posterior fossa ependymoma in childhood: 60 years event-free survival after partial resection—a case report
Childs Nerv Syst, 31 (9), 1573-6
DOI 10.1007/s00381-015-2766-7, PubMed 26047947

Olsen TK, Panagopoulos I, Meling TR, Micci F, Gorunova L, Thorsen J, Due-Tønnessen B, Scheie D, Lund-Iversen M, Krossnes B, Saxhaug C, Heim S, Brandal P (2015)
Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?
Neuro Oncol, 17 (10), 1365-73
DOI 10.1093/neuonc/nov039, PubMed 25795305

Ringstad G, Emblem KE, Eide PK (2015)
Phase-contrast magnetic resonance imaging reveals net retrograde aqueductal flow in idiopathic normal pressure hydrocephalus
J Neurosurg, 124 (6), 1850-7
DOI 10.3171/2015.6.JNS15496, PubMed 26636385

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK (2015)
Aqueductal Stroke Volume: Comparisons with Intracranial Pressure Scores in Idiopathic Normal Pressure Hydrocephalus
AJNR Am J Neuroradiol, 36 (9), 1623-30
DOI 10.3174/ajnr.A4340, PubMed 25977480

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK (2015)
Reply: To PMID 25977480
AJNR Am J Neuroradiol, 36 (9), 1633-4
DOI 10.3174/ajnr.A4488, PubMed 26251437

Selnes P, Grambaite R, Rincon M, Bjørnerud A, Gjerstad L, Hessen E, Auning E, Johansen K, Almdahl IS, Due-Tønnessen P, Vegge K, Bjelke B, Fladby T (2015)
Hippocampal complex atrophy in poststroke and mild cognitive impairment
J Cereb Blood Flow Metab, 35 (11), 1729-37
DOI 10.1038/jcbfm.2015.110, PubMed 26036934

Sowa P, Bjørnerud A, Nygaard GO, Damangir S, Spulber G, Celius EG, Due-Tønnessen P, Harbo HF, Beyer MK (2015)
Reduced perfusion in white matter lesions in multiple sclerosis
Eur J Radiol, 84 (12), 2605-12
DOI 10.1016/j.ejrad.2015.09.007, PubMed 26391230

Tamnes CK, Zeller B, Amlien IK, Kanellopoulos A, Andersson S, Due-Tønnessen P, Ruud E, Walhovd KB, Fjell AM (2015)
Cortical surface area and thickness in adult survivors of pediatric acute lymphoblastic leukemia
Pediatr Blood Cancer, 62 (6), 1027-34
DOI 10.1002/pbc.25386, PubMed 25597852

Publications 2014

Brabrand K, de Lange C, Emblem KE, Reinholt FP, Saugstad OD, Stokke ES, Munkeby BH (2014)
Contrast-enhanced ultrasound identifies reduced overall and regional renal perfusion during global hypoxia in piglets
Invest Radiol, 49 (8), 540-6
DOI 10.1097/RLI.0000000000000053, PubMed 24637585

Due-Tonnessen P, Rasmussen I, Berntsen EM, Bjornerud A, Emblem KE (2014)
Identifying the central sulcus in patients with intra-axial lesions: a multicenter study comparing conventional presurgical MRI to topographical analysis and BOLD-fMRI
J Comput Assist Tomogr, 38 (1), 1-8
DOI 10.1097/RCT.0b013e3182a589e0, PubMed 24378889

Emblem KE, Farrar CT, Gerstner ER, Batchelor TT, Borra RJ, Rosen BR, Sorensen AG, Jain RK (2014)
Vessel caliber--a potential MRI biomarker of tumour response in clinical trials
Nat Rev Clin Oncol, 11 (10), 566-84
DOI 10.1038/nrclinonc.2014.126, PubMed 25113840

Emblem KE, Pinho MC, Zöllner FG, Due-Tonnessen P, Hald JK, Schad LR, Meling TR, Rapalino O, Bjornerud A (2014)
A generic support vector machine model for preoperative glioma survival associations
Radiology, 275 (1), 228-34
DOI 10.1148/radiol.14140770, PubMed 25486589

Engvig A, Fjell AM, Westlye LT, Skaane NV, Dale AM, Holland D, Due-Tønnessen P, Sundseth O, Walhovd KB (2014)
Effects of cognitive training on gray matter volumes in memory clinic patients with subjective memory impairment
J Alzheimers Dis, 41 (3), 779-91
DOI 10.3233/JAD-131889, PubMed 24685630

Grøvik E, Bjørnerud A, Kurz KD, Kingsrød M, Sandhaug M, Storås TH, Gjesdal KI (2014)
Single bolus split dynamic MRI: Is the combination of high spatial and dual-echo high temporal resolution interleaved sequences useful in the differential diagnosis of breast masses?
J Magn Reson Imaging, 42 (1), 180-7
DOI 10.1002/jmri.24753, PubMed 25211038

Kalpathy-Cramer J, Gerstner ER, Emblem KE, Andronesi O, Rosen B (2014)
Advanced magnetic resonance imaging of the physical processes in human glioblastoma
Cancer Res, 74 (17), 4622-4637
DOI 10.1158/0008-5472.CAN-14-0383, PubMed 25183787

Krogsrud SK, Tamnes CK, Fjell AM, Amlien I, Grydeland H, Sulutvedt U, Due-Tønnessen P, Bjørnerud A, Sølsnes AE, Håberg AK, Skrane J, Walhovd KB (2014)
Development of hippocampal subfield volumes from 4 to 22 years
Hum Brain Mapp, 35 (11), 5646-57
DOI 10.1002/hbm.22576, PubMed 24976170

Lundar T, Due-Tønnessen BJ, Egge A, Scheie D, Brandal P, Stensvold E, Due-Tønnessen P (2014)
Neurosurgical treatment of pediatric low-grade midbrain tumors: a single consecutive institutional series of 15 patients
J Neurosurg Pediatr, 14 (6), 598-603
DOI 10.3171/2014.9.PEDS1462, PubMed 25325421

Nygaard GO, Walhovd KB, Sowa P, Chepkoech JL, Bjørnerud A, Due-Tønnessen P, Landrø NI, Damangir S, Spulber G, Storsve AB, Beyer MK, Fjell AM, Celius EG, Harbo HF (2014)
Cortical thickness and surface area relate to specific symptoms in early relapsing-remitting multiple sclerosis
Mult Scler, 21 (4), 402-14
DOI 10.1177/1352458514543811, PubMed 25139946

Odland A, Server A, Saxhaug C, Breivik B, Groote R, Vardal J, Larsson C, Bjørnerud A (2014)
Volumetric glioma quantification: comparison of manual and semi-automatic tumor segmentation for the quantification of tumor growth
Acta Radiol, 56 (11), 1396-403
DOI 10.1177/0284185114554822, PubMed 25338837

Walhovd KB, Bjørnebekk A, Haabrekke K, Siqveland T, Slinning K, Nygaard E, Fjell AM, Due-Tønnessen P, Bjørnerud A, Moe V (2014)
Child neuroanatomical, neurocognitive, and visual acuity outcomes with maternal opioid and polysubstance detoxification
Pediatr Neurol, 52 (3), 326-32.e1-3
DOI 10.1016/j.pediatrneurol.2014.11.008, PubMed 25595574

Walhovd KB, Tamnes CK, Bjørnerud A, Due-Tønnessen P, Holland D, Dale AM, Fjell AM (2014)
Maturation of Cortico-Subcortical Structural Networks-Segregation and Overlap of Medial Temporal and Fronto-Striatal Systems in Development
Cereb Cortex, 25 (7), 1835-41
DOI 10.1093/cercor/bht424, PubMed 24436319

Publications 2013

Batchelor TT, Gerstner ER, Emblem KE, Duda DG, Kalpathy-Cramer J, Snuderl M, Ancukiewicz M, Polaskova P, Pinho MC, Jennings D, Plotkin SR, Chi AS, Eichler AF, Dietrich J, Hochberg FH, Lu-Emerson C, Iafrate AJ, Ivy SP, Rosen BR, Loeffler JS, Wen PY, Sorensen AG, Jain RK (2013)
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation
Proc Natl Acad Sci U S A, 110 (47), 19059-64
DOI 10.1073/pnas.1318022110, PubMed 24190997

Emblem KE, Due-Tonnessen P, Hald JK, Bjornerud A, Pinho MC, Scheie D, Schad LR, Meling TR, Zoellner FG (2013)
Machine learning in preoperative glioma MRI: survival associations by perfusion-based support vector machine outperforms traditional MRI
J Magn Reson Imaging, 40 (1), 47-54
DOI 10.1002/jmri.24390, PubMed 24753371

Emblem KE, Mouridsen K, Bjornerud A, Farrar CT, Jennings D, Borra RJ, Wen PY, Ivy P, Batchelor TT, Rosen BR, Jain RK, Sorensen AG (2013)
Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy
Nat Med, 19 (9), 1178-83
DOI 10.1038/nm.3289, PubMed 23955713

Funderud I, Løvstad M, Lindgren M, Endestad T, Due-Tønnessen P, Meling TR, Knight RT, Solbakk AK (2013)
Preparatory attention after lesions to the lateral or orbital prefrontal cortex--an event-related potentials study
Brain Res, 1527, 174-88
DOI 10.1016/j.brainres.2013.06.017, PubMed 23831520

Grøvik E, Bjørnerud A, Storås TH, Gjesdal KI (2013)
Split dynamic MRI: single bolus high spatial-temporal resolution and multi contrast evaluation of breast lesions
J Magn Reson Imaging, 39 (3), 673-82
DOI 10.1002/jmri.24206, PubMed 23913511

Jusufovic M, Due-Tønnessen P, Fric R, Stenset V (2013)
Subdural empyema
Tidsskr Nor Laegeforen, 133 (15), 1601
DOI 10.4045/tidsskr.13.0164, PubMed 23970275

Pinho MC, Polaskova P, Kalpathy-Cramer J, Jennings D, Emblem KE, Jain RK, Rosen BR, Wen PY, Sorensen AG, Batchelor TT, Gerstner ER (2013)
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation
Oncologist, 19 (1), 75-81
DOI 10.1634/theoncologist.2013-0101, PubMed 24309981

Selnes P, Aarsland D, Bjørnerud A, Gjerstad L, Wallin A, Hessen E, Reinvang I, Grambaite R, Auning E, Kjærvik VK, Due-Tønnessen P, Stenset V, Fladby T (2013)
Diffusion tensor imaging surpasses cerebrospinal fluid as predictor of cognitive decline and medial temporal lobe atrophy in subjective cognitive impairment and mild cognitive impairment
J Alzheimers Dis, 33 (3), 723-36
DOI 10.3233/JAD-2012-121603, PubMed 23186987

Thormodsen R, Rimol LM, Tamnes CK, Juuhl-Langseth M, Holmén A, Emblem KE, Rund BR, Agartz I (2013)
Age-related cortical thickness differences in adolescents with early-onset schizophrenia compared with healthy adolescents
Psychiatry Res, 214 (3), 190-6
DOI 10.1016/j.pscychresns.2013.07.003, PubMed 24144503

Zeller B, Tamnes CK, Kanellopoulos A, Amlien IK, Andersson S, Due-Tønnessen P, Fjell AM, Walhovd KB, Westlye LT, Ruud E (2013)
Response to A.A.M. van der Veldt et al
J Clin Oncol, 32 (8), 852-3
DOI 10.1200/JCO.2013.52.5725, PubMed 24220558

Zeller B, Tamnes CK, Kanellopoulos A, Amlien IK, Andersson S, Due-Tønnessen P, Fjell AM, Walhovd KB, Westlye LT, Ruud E (2013)
Reduced neuroanatomic volumes in long-term survivors of childhood acute lymphoblastic leukemia
J Clin Oncol, 31 (17), 2078-85
DOI 10.1200/JCO.2012.47.4031, PubMed 23589559

Publications 2012

Amlien IK, Fjell AM, Walhovd KB, Selnes P, Stenset V, Grambaite R, Bjørnerud A, Due-Tønnessen P, Skinningsrud A, Gjerstad L, Reinvang I, Fladby T (2012)
Mild cognitive impairment: cerebrospinal fluid tau biomarker pathologic levels and longitudinal changes in white matter integrity
Radiology, 266 (1), 295-303
DOI 10.1148/radiol.12120319, PubMed 23151827

Juuhl-Langseth M, Rimol LM, Rasmussen IA, Thormodsen R, Holmén A, Emblem KE, Due-Tønnessen P, Rund BR, Agartz I (2012)
Comprehensive segmentation of subcortical brain volumes in early onset schizophrenia reveals limited structural abnormalities
Psychiatry Res, 203 (1), 14-23
DOI 10.1016/j.pscychresns.2011.10.005, PubMed 22917502

Løvstad M, Funderud I, Endestad T, Due-Tønnessen P, Meling TR, Lindgren M, Knight RT, Solbakk AK (2012)
Executive functions after orbital or lateral prefrontal lesions: neuropsychological profiles and self-reported executive functions in everyday living
Brain Inj, 26 (13-14), 1586-98
DOI 10.3109/02699052.2012.698787, PubMed 22731818

Løvstad M, Funderud I, Meling T, Krämer UM, Voytek B, Due-Tønnessen P, Endestad T, Lindgren M, Knight RT, Solbakk AK (2012)
Anterior cingulate cortex and cognitive control: neuropsychological and electrophysiological findings in two patients with lesions to dorsomedial prefrontal cortex
Brain Cogn, 80 (2), 237-49
DOI 10.1016/j.bandc.2012.07.008, PubMed 22935543

Selnes P, Fjell AM, Gjerstad L, Bjørnerud A, Wallin A, Due-Tønnessen P, Grambaite R, Stenset V, Fladby T (2012)
White matter imaging changes in subjective and mild cognitive impairment
Alzheimers Dement, 8 (5 Suppl), S112-21
DOI 10.1016/j.jalz.2011.07.001, PubMed 23021621

Tamnes CK, Walhovd KB, Dale AM, Østby Y, Grydeland H, Richardson G, Westlye LT, Roddey JC, Hagler DJ, Due-Tønnessen P, Holland D, Fjell AM, Alzheimer's Disease Neuroimaging Initiative (2012)
Brain development and aging: overlapping and unique patterns of change
Neuroimage, 68, 63-74
DOI 10.1016/j.neuroimage.2012.11.039, PubMed 23246860

Walhovd KB, Tamnes CK, Østby Y, Due-Tønnessen P, Fjell AM (2012)
Normal variation in behavioral adjustment relates to regional differences in cortical thickness in children
Eur Child Adolesc Psychiatry, 21 (3), 133-40
DOI 10.1007/s00787-012-0241-5, PubMed 22302474

Zöllner FG, Emblem KE, Schad LR (2012)
SVM-based glioma grading: Optimization by feature reduction analysis
Z Med Phys, 22 (3), 205-14
DOI 10.1016/j.zemedi.2012.03.007, PubMed 22503911

Publications 2011

Bjornerud A, Sorensen AG, Mouridsen K, Emblem KE (2011)
T1- and T2*-dominant extravasation correction in DSC-MRI: part I--theoretical considerations and implications for assessment of tumor hemodynamic properties
J Cereb Blood Flow Metab, 31 (10), 2041-53
DOI 10.1038/jcbfm.2011.52, PubMed 21505483

de Lange C, Brabrand K, Emblem KE, Bjornerud A, Løberg EM, Saugstad OD, Munkeby BH (2011)
Cerebral perfusion in perinatal hypoxia and resuscitation assessed by transcranial contrast-enhanced ultrasound and 3 T MRI in newborn pigs
Invest Radiol, 46 (11), 686-96
DOI 10.1097/RLI.0b013e3182266431, PubMed 21730873

Emblem KE, Bjornerud A, Mouridsen K, Borra RJ, Batchelor TT, Jain RK, Sorensen AG (2011)
T(1)- and T(2)(*)-dominant extravasation correction in DSC-MRI: part II-predicting patient outcome after a single dose of cediranib in recurrent glioblastoma patients
J Cereb Blood Flow Metab, 31 (10), 2054-64
DOI 10.1038/jcbfm.2011.39, PubMed 21505476

Garzón B, Emblem KE, Mouridsen K, Nedregaard B, Due-Tønnessen P, Nome T, Hald JK, Bjørnerud A, Håberg AK, Kvinnsland Y (2011)
Multiparametric analysis of magnetic resonance images for glioma grading and patient survival time prediction
Acta Radiol, 52 (9), 1052-60
DOI 10.1258/ar.2011.100510, PubMed 21969702

Løvstad M, Funderud I, Lindgren M, Endestad T, Due-Tønnessen P, Meling T, Voytek B, Knight RT, Solbakk AK (2011)
Contribution of subregions of human frontal cortex to novelty processing
J Cogn Neurosci, 24 (2), 378-95
DOI 10.1162/jocn_a_00099, PubMed 21812562

Ringstad GA, Emblem KE, Holland D, Dale AM, Bjornerud A, Hald JK (2011)
Assessment of pituitary adenoma volumetric change using longitudinal MR image registration
Neuroradiology, 54 (5), 435-43
DOI 10.1007/s00234-011-0894-7, PubMed 21647587

Sorensen AG, Emblem KE, Polaskova P, Jennings D, Kim H, Ancukiewicz M, Wang M, Wen PY, Ivy P, Batchelor TT, Jain RK (2011)
Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion
Cancer Res, 72 (2), 402-7
DOI 10.1158/0008-5472.CAN-11-2464, PubMed 22127927

Tamnes CK, Fjell AM, Østby Y, Westlye LT, Due-Tønnessen P, Bjørnerud A, Walhovd KB (2011)
The brain dynamics of intellectual development: waxing and waning white and gray matter
Neuropsychologia, 49 (13), 3605-11
DOI 10.1016/j.neuropsychologia.2011.09.012, PubMed 21939677

Thormodsen R, Jensen J, Holmèn A, Juuhl-Langseth M, Emblem KE, Andreassen OA, Rund BR (2011)
Prefrontal hyperactivation during a working memory task in early-onset schizophrenia spectrum disorders: an fMRI study
Psychiatry Res, 194 (3), 257-262
DOI 10.1016/j.pscychresns.2011.05.011, PubMed 22079661

Publications 2010

Abildgaard A, Witwit AK, Karlsen JS, Jacobsen EA, Tennøe B, Ringstad G, Due-Tønnessen P (2010)
An autostereoscopic 3D display can improve visualization of 3D models from intracranial MR angiography
Int J Comput Assist Radiol Surg, 5 (5), 549-54
DOI 10.1007/s11548-010-0509-5, PubMed 20652646

Bjørnerud A, Emblem KE (2010)
A fully automated method for quantitative cerebral hemodynamic analysis using DSC-MRI
J Cereb Blood Flow Metab, 30 (5), 1066-78
DOI 10.1038/jcbfm.2010.4, PubMed 20087370

Grydeland H, Walhovd KB, Westlye LT, Due-Tønnessen P, Ormaasen V, Sundseth Ø, Fjell AM (2010)
Amnesia following herpes simplex encephalitis: diffusion-tensor imaging uncovers reduced integrity of normal-appearing white matter
Radiology, 257 (3), 774-81
DOI 10.1148/radiol.10100179, PubMed 20935078

Tamnes CK, Østby Y, Walhovd KB, Westlye LT, Due-Tønnessen P, Fjell AM (2010)
Neuroanatomical correlates of executive functions in children and adolescents: a magnetic resonance imaging (MRI) study of cortical thickness
Neuropsychologia, 48 (9), 2496-508
DOI 10.1016/j.neuropsychologia.2010.04.024, PubMed 20434470

Tamnes CK, Østby Y, Walhovd KB, Westlye LT, Due-Tønnessen P, Fjell AM (2010)
Intellectual abilities and white matter microstructure in development: a diffusion tensor imaging study
Hum Brain Mapp, 31 (10), 1609-25
DOI 10.1002/hbm.20962, PubMed 20162594

Walhovd KB, Westlye LT, Moe V, Slinning K, Due-Tønnessen P, Bjørnerud A, van der Kouwe A, Dale AM, Fjell AM (2010)
White matter characteristics and cognition in prenatally opiate- and polysubstance-exposed children: a diffusion tensor imaging study
AJNR Am J Neuroradiol, 31 (5), 894-900
DOI 10.3174/ajnr.A1957, PubMed 20203117

Westlye LT, Walhovd KB, Dale AM, Bjørnerud A, Due-Tønnessen P, Engvig A, Grydeland H, Tamnes CK, Østby Y, Fjell AM (2010)
Differentiating maturational and aging-related changes of the cerebral cortex by use of thickness and signal intensity
Neuroimage, 52 (1), 172-85
DOI 10.1016/j.neuroimage.2010.03.056, PubMed 20347997

Zöllner FG, Emblem KE, Schad LR (2010)
Support vector machines in DSC-based glioma imaging: suggestions for optimal characterization
Magn Reson Med, 64 (4), 1230-6
DOI 10.1002/mrm.22495, PubMed 20564592

Publications 2009

Emblem KE, Bjornerud A (2009)
An automatic procedure for normalization of cerebral blood volume maps in dynamic susceptibility contrast-based glioma imaging
AJNR Am J Neuroradiol, 30 (10), 1929-32
DOI 10.3174/ajnr.A1680, PubMed 19628627

Emblem KE, Due-Tonnessen P, Hald JK, Bjornerud A (2009)
Automatic vessel removal in gliomas from dynamic susceptibility contrast imaging
Magn Reson Med, 61 (5), 1210-7
DOI 10.1002/mrm.21944, PubMed 19253390

Emblem KE, Nedregaard B, Hald JK, Nome T, Due-Tonnessen P, Bjornerud A (2009)
Automatic glioma characterization from dynamic susceptibility contrast imaging: brain tumor segmentation using knowledge-based fuzzy clustering
J Magn Reson Imaging, 30 (1), 1-10
DOI 10.1002/jmri.21815, PubMed 19557840

Ostby Y, Tamnes CK, Fjell AM, Westlye LT, Due-Tønnessen P, Walhovd KB (2009)
Heterogeneity in subcortical brain development: A structural magnetic resonance imaging study of brain maturation from 8 to 30 years
J Neurosci, 29 (38), 11772-82
DOI 10.1523/JNEUROSCI.1242-09.2009, PubMed 19776264

Stenset V, Bjørnerud A, Fjell AM, Walhovd KB, Hofoss D, Due-Tønnessen P, Gjerstad L, Fladby T (2009)
Cingulum fiber diffusivity and CSF T-tau in patients with subjective and mild cognitive impairment
Neurobiol Aging, 32 (4), 581-9
DOI 10.1016/j.neurobiolaging.2009.04.014, PubMed 19428143

Tamnes CK, Ostby Y, Fjell AM, Westlye LT, Due-Tønnessen P, Walhovd KB (2009)
Brain maturation in adolescence and young adulthood: regional age-related changes in cortical thickness and white matter volume and microstructure
Cereb Cortex, 20 (3), 534-48
DOI 10.1093/cercor/bhp118, PubMed 19520764

Westlye LT, Walhovd KB, Dale AM, Bjørnerud A, Due-Tønnessen P, Engvig A, Grydeland H, Tamnes CK, Ostby Y, Fjell AM (2009)
Life-span changes of the human brain white matter: diffusion tensor imaging (DTI) and volumetry
Cereb Cortex, 20 (9), 2055-68
DOI 10.1093/cercor/bhp280, PubMed 20032062

Publications 2008

Emblem KE, Nedregaard B, Nome T, Due-Tonnessen P, Hald JK, Scheie D, Borota OC, Cvancarova M, Bjornerud A (2008)
Glioma grading by using histogram analysis of blood volume heterogeneity from MR-derived cerebral blood volume maps
Radiology, 247 (3), 808-17
DOI 10.1148/radiol.2473070571, PubMed 18487536

Emblem KE, Scheie D, Due-Tonnessen P, Nedregaard B, Nome T, Hald JK, Beiske K, Meling TR, Bjornerud A (2008)
Histogram analysis of MR imaging-derived cerebral blood volume maps: combined glioma grading and identification of low-grade oligodendroglial subtypes
AJNR Am J Neuroradiol, 29 (9), 1664-70
DOI 10.3174/ajnr.A1182, PubMed 18583405

Emblem KE, Zoellner FG, Tennoe B, Nedregaard B, Nome T, Due-Tonnessen P, Hald JK, Scheie D, Bjornerud A (2008)
Predictive modeling in glioma grading from MR perfusion images using support vector machines
Magn Reson Med, 60 (4), 945-52
DOI 10.1002/mrm.21736, PubMed 18816815

Fjell AM, Walhovd KB, Amlien I, Bjørnerud A, Reinvang I, Gjerstad L, Cappelen T, Willoch F, Due-Tønnessen P, Grambaite R, Skinningsrud A, Stenset V, Fladby T (2008)
Morphometric changes in the episodic memory network and tau pathologic features correlate with memory performance in patients with mild cognitive impairment
AJNR Am J Neuroradiol, 29 (6), 1183-9
DOI 10.3174/ajnr.A1059, PubMed 18544670

Fjell AM, Westlye LT, Greve DN, Fischl B, Benner T, van der Kouwe AJ, Salat D, Bjørnerud A, Due-Tønnessen P, Walhovd KB (2008)
The relationship between diffusion tensor imaging and volumetry as measures of white matter properties
Neuroimage, 42 (4), 1654-68
DOI 10.1016/j.neuroimage.2008.06.005, PubMed 18620064

Munkeby BH, De Lange C, Emblem KE, Bjørnerud A, Kro GA, Andresen J, Winther-Larssen EH, Løberg EM, Hald JK (2008)
A piglet model for detection of hypoxic-ischemic brain injury with magnetic resonance imaging
Acta Radiol, 49 (9), 1049-57
DOI 10.1080/02841850802334224, PubMed 18720081

Walhovd KB, Fjell AM, Amlien I, Grambaite R, Stenset V, Bjørnerud A, Reinvang I, Gjerstad L, Cappelen T, Due-Tønnessen P, Fladby T (2008)
Multimodal imaging in mild cognitive impairment: Metabolism, morphometry and diffusion of the temporal-parietal memory network
Neuroimage, 45 (1), 215-23
DOI 10.1016/j.neuroimage.2008.10.053, PubMed 19056499

Walhovd KB, Moe V, Slinning K, Due-Tonnessen P, Bjornerud A, Dale AM, van der Kouwe A, Quinn BT, Kosofsky B, Greve D, Fischl B (2008)
Volumetric cerebral characteristics of children exposed to opiates and other substances in utero (vol 36, pg 1331, 2007)
Neuroimage, 41 (4), 1514-1516

Westlye LT, Walhovd KB, Bjørnerud A, Due-Tønnessen P, Fjell AM (2008)
Error-related negativity is mediated by fractional anisotropy in the posterior cingulate gyrus--a study combining diffusion tensor imaging and electrophysiology in healthy adults
Cereb Cortex, 19 (2), 293-304
DOI 10.1093/cercor/bhn084, PubMed 18502729

Publications 2007

Walhovd KB, Moe V, Slinning K, Due-Tønnessen P, Bjørnerud A, Dale AM, van der Kouwe A, Quinn BT, Kosofsky B, Greve D, Fischl B (2007)
Volumetric cerebral characteristics of children exposed to opiates and other substances in utero
Neuroimage, 36 (4), 1331-44
DOI 10.1016/j.neuroimage.2007.03.070, PubMed 17513131

Publications 2005

Lund C, Nes RB, Ugelstad TP, Due-Tønnessen P, Andersen R, Hol PK, Brucher R, Russell D (2005)
Cerebral emboli during left heart catheterization may cause acute brain injury
Eur Heart J, 26 (13), 1269-75
DOI 10.1093/eurheartj/ehi148, PubMed 15716287

Publications 2004

Stabell KE, Bakke SJ, Andresen S, Bjørnaes H, Borchgrevink HM, Due-Tønnessen P, Heminghyt E, Nome T, Pedersen HK, Ramm-Pettersen J, Røste GK, Tennøe B (2004)
Selective posterior cerebral artery amobarbital test: its role in presurgical memory assessment in temporal lobe epilepsy
Epilepsia, 45 (7), 817-25
DOI 10.1111/j.0013-9580.2004.59903.x, PubMed 15230707

Publications 2002

Hol PK, Fosse E, Lundblad R, Nitter-Hauge S, Due-Tønnessen P, Vatne K, Smith HJ (2002)
The importance of intraoperative angiographic findings for predicting long-term patency in coronary artery bypass operations
Ann Thorac Surg, 73 (3), 813-8
DOI 10.1016/s0003-4975(01)03459-2, PubMed 11899185

Publications 2001

Hol PK, Fosse E, Mork BE, Lundblad R, Rein KA, Lingaas PS, Geiran O, Svennevig JL, Tonnessen TI, Nitter-Hauge S, Due-Tonnessen P, Vatne K, Smith HJ (2001)
Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery
Heart Surg Forum, 4 (3), 254-7; discussion 257-8
PubMed 11673148

Hol PK, Fosse E, Mork BE, Lundblad R, Rein KA, Lingaas PS, Geiran O, Svennevig JL, Tonnessen TI, Nitter-Hauge S, Due-Tonnessen P, Vatne K, Smith HJ (2001)
Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery
Heart Surg. Forum, 4 (3), 2001-2339-257

Publications 1998

Emblem K (1998)
Side notes on negative consequences and uncertainty
TECH RISK S, 12, 124-125