Photochemical internalisation (PCI) is a novel technology for improving the transfer of macromolecules into the cytosol of cells. This is executed through photochemical targeting of endocytic vesicles, leading to release of the contents of these vesicles into the cytosol. The groups main focus is to develop PCI for therapeutic purposes.
Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
Cancer Rep (Hoboken), e1278 (in press)
Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model
Photochem Photobiol, 96 (3), 708-717
Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures
Photochem Photobiol, 96 (3), 699-707