Publications

Publications published since 2002 from OUS - Photochemical Internalisation (PCI)

137 publications found

Publications 2018

  1. Christensen T, de Gruijl F, Hamblin M, Ishibashi Y, Kamada K, Sage E, Saltiel J, Sliwa M, Theodossiou T, Wu SP, Bassani D, Nonell S, Shore A (2018)
    Outstanding Reviewers for Photochemical and Photobiological Sciences in 2017
    Photochem. Photobiol. Sci., 17 (5), 533
  2. Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK (2018)
    Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
    Photochem Photobiol Sci, 17 (5), 539-551
    PubMed 29565434
  3. Haug M, Brede G, Håkerud M, Nedberg AG, Gederaas OA, Flo TH, Edwards VT, Selbo PK, Høgset A, Halaas Ø (2018)
    Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination
    Front Immunol, 9, 650
    PubMed 29670624
  4. Hirschberg H, Berg K, Peng Q (2018)
    Photodynamic therapy mediated immune therapy of brain tumors
    Neuroimmunol Neuroinflamm, 5
    PubMed 30221185
  5. Mastrangelopoulou M, Grigalavicius M, Berg K, Menard M, Theodossiou TA (2018)
    Cytotoxic and Photocytotoxic Effects of Cercosporin on Human Tumour Cell Lines
    Photochem Photobiol (in press)
    PubMed 30107033
  6. Våtsveen TK, Myhre MR, Steen CB, Wälchli S, Lingjærde OC, Bai B, Dillard P, Theodossiou TA, Holien T, Sundan A, Inderberg EM, Smeland EB, Myklebust JH, Oksvold MP (2018)
    Artesunate shows potent anti-tumor activity in B-cell lymphoma
    J Hematol Oncol, 11 (1), 23
    PubMed 29458389
  7. Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
    Light-enhanced VEGF<sub>121</sub>/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
    J Control Release, 288, 161-172 (in press)
    PubMed 30217739
  8. Zhang X, de Boer L, Heiliegers L, Man-Bovenkerk S, Selbo PK, Drijfhout JW, Høgset A, Zaat SAJ (2018)
    Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection
    J Control Release, 283, 214-222
    PubMed 29883696

Publications 2017

  1. Bus MP, Szafranski A, Sellevold S, Goryn T, Jutte PC, Bramer JA, Fiocco M, Streitbürger A, Kotrych D, van de Sande MA, Dijkstra PD (2017)
    LUMiC<sup>®</sup> Endoprosthetic Reconstruction After Periacetabular Tumor Resection: Short-term Results
    Clin Orthop Relat Res, 475 (3), 686-695
    PubMed 27020434
  2. Christie C, Pomeroy A, Nair R, Berg K, Hirschberg H (2017)
    Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy
    Photodiagnosis Photodyn Ther, 18, 140-148
    PubMed 28257943
  3. Gaware VS, Håkerud M, Juzeniene A, Høgset A, Berg K, Másson M (2017)
    Endosome Targeting meso-Tetraphenylchlorin-Chitosan Nanoconjugates for Photochemical Internalization
    Biomacromolecules, 18 (4), 1108-1126
    PubMed 28245649
  4. Gederaas OA, Johnsson A, Berg K, Manandhar R, Shrestha C, Skåre D, Ekroll IK, Høgset A, Hjelde A (2017)
    Photochemical internalization in bladder cancer - development of an orthotopic in vivo model
    Photochem Photobiol Sci, 16 (11), 1664-1676
    PubMed 28972608
  5. Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
    Microenvironmental autophagy promotes tumour growth
    Nature, 541 (7637), 417-420
    PubMed 28077876
  6. Lund K, Olsen CE, Wong JJW, Olsen PA, Solberg NT, Høgset A, Krauss S, Selbo PK (2017)
    5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
    J Exp Clin Cancer Res, 36 (1), 187
    PubMed 29258566
  7. Norum OJ, Fremstedal ASV, Weyergang A, Golab J, Berg K (2017)
    Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity
    J Control Release, 268, 120-127
    PubMed 29042319
  8. Olsen CE, Sellevold S, Theodossiou T, Patzke S, Berg K (2017)
    Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin
    Photodiagnosis Photodyn Ther, 20, 35-47
    PubMed 28838761
  9. Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
    Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
    Biochem Pharmacol, 144, 63-77
    PubMed 28784290
  10. Sellevold S, Peng Q, Fremstedal ASV, Berg K (2017)
    Photochemical internalization (PCI) of bleomycin is equally effective in two dissimilar leiomyosarcoma xenografts in athymic mice
    Photodiagnosis Photodyn Ther, 20, 95-106
    PubMed 28865875
  11. Shin D, Christie C, Ju D, Nair RK, Molina S, Berg K, Krasieva TB, Madsen SJ, Hirschberg H (2017)
    Photochemical internalization enhanced macrophage delivered chemotherapy
    Photodiagnosis Photodyn Ther, 21, 156-162
    PubMed 29221858
  12. Theodossiou TA, Olsen CE, Jonsson M, Kubin A, Hothersall JS, Berg K (2017)
    The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
    Redox Biol, 12, 191-197
    PubMed 28254657

Publications 2016

  1. Christie C, Molina S, Gonzales J, Berg K, Nair RK, Huynh K, Madsen SJ, Hirschberg H (2016)
    Synergistic chemotherapy by combined moderate hyperthermia and photochemical internalization
    Biomed Opt Express, 7 (4), 1240-50
    PubMed 27446650
  2. Hjálmsdóttir Á, Bühler C, Vonwil V, Roveri M, Håkerud M, Wäckerle-Men Y, Gander B, Johansen P (2016)
    Cytosolic Delivery of Liposomal Vaccines by Means of the Concomitant Photosensitization of Phagosomes
    Mol Pharm, 13 (2), 320-9
    PubMed 26704885
  3. Madsen SJ, Gonzales J, Zamora G, Berg K, Nair RK, Hirschberg H (2016)
    Comparing the Effects of Light- or Sonic-Activated Drug Delivery: Photochemical/Sonochemical Internalization
    J Environ Pathol Toxicol Oncol, 35 (1), 91-8
    PubMed 27279586
  4. Reichrath J, Berg K, Emmert S, Lademann J, Seckmeyer G, Zastrow L, Vogt T, Holick MF (2016)
    Biologic Effects of Light: An Enlighting Prospective
    Anticancer Res, 36 (3), 1339-43
    PubMed 26977035
  5. Sultan AA, Jerjes W, Berg K, Høgset A, Mosse CA, Hamoudi R, Hamdoon Z, Simeon C, Carnell D, Forster M, Hopper C (2016)
    Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial
    Lancet Oncol, 17 (9), 1217-29
    PubMed 27475428

Publications 2015

  1. Baglo Y, Peng Q, Hagen L, Berg K, Høgset A, Drabløs F, Gederaas OA (2015)
    Studies of the photosensitizer disulfonated meso-tetraphenyl chlorin in an orthotopic rat bladder tumor model
    Photodiagnosis Photodyn Ther, 12 (1), 58-66
    PubMed 25575731
  2. Berg K (2015)
    Resistance mechanisms in photodynamic therapy
    Photochem Photobiol Sci, 14 (8), 1376-7
    PubMed 26212047
  3. Berstad MB, Cheung LH, Berg K, Peng Q, Fremstedal AS, Patzke S, Rosenblum MG, Weyergang A (2015)
    Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy
    Oncogene, 34 (44), 5582-92
    PubMed 25684137
  4. Bostad M, Olsen CE, Peng Q, Berg K, Høgset A, Selbo PK (2015)
    Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy
    J Control Release, 206, 37-48
    PubMed 25758331
  5. Bruno C, Waeckerle-Men Y, Håkerud M, Kündig TM, Gander B, Johansen P (2015)
    Photosensitizer and Light Pave the Way for Cytosolic Targeting and Generation of Cytosolic CD8 T Cells Using PLGA Vaccine Particles
    J Immunol, 195 (1), 166-73
    PubMed 26019274
  6. Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A (2015)
    Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
    Oncotarget, 6 (14), 12436-51
    PubMed 26002552
  7. Christie CE, Zamora G, Kwon YJ, Berg K, Madsen SJ, Hirschberg H (2015)
    Macrophage mediated PCI enhanced gene-directed enzyme prodrug therapy
    PROC SPIE, 9305
  8. Gederaas OA, Hauge A, Ellingsen PG, Berg K, Altin D, Bardal T, Høgset A, Lindgren M (2015)
    Photochemical internalization of bleomycin and temozolomide--in vitro studies on the glioma cell line F98
    Photochem Photobiol Sci, 14 (7), 1357-66
    PubMed 26088711
  9. Pefkianakis EK, Theodossiou TA, Toubanaki DK, Karagouni E, Falaras P, Papadopoulos K, Vougioukalakis GC (2015)
    A Family of Potent Ru(II) Photosensitizers with Enhanced DNA Intercalation: Bimodal Photokillers
    Photochem Photobiol, 91 (5), 1191-202
    PubMed 26118404
  10. Selbo PK, Bostad M, Olsen CE, Edwards VT, Høgset A, Weyergang A, Berg K (2015)
    Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics
    Photochem Photobiol Sci, 14 (8), 1433-50
    PubMed 25805311
  11. Theodossiou TA, Wälchli S, Olsen CE, Skarpen E, Berg K (2015)
    Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
    ACS Chem Biol, 11 (1), 251-62
    PubMed 26569462
  12. Weyergang A, Berstad ME, Bull-Hansen B, Olsen CE, Selbo PK, Berg K (2015)
    Photochemical activation of drugs for the treatment of therapy-resistant cancers
    Photochem Photobiol Sci, 14 (8), 1465-75
    PubMed 25849953

Publications 2014

  1. Bostad M, Kausberg M, Weyergang A, Olsen CE, Berg K, Høgset A, Selbo PK (2014)
    Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
    Mol Pharm, 11 (8), 2764-76
    PubMed 24960585
  2. Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
    Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
    J Control Release, 182, 58-66
    PubMed 24637464
  3. Håkerud M, Selbo PK, Waeckerle-Men Y, Contassot E, Dziunycz P, Kündig TM, Høgset A, Johansen P (2014)
    Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells
    J Control Release, 198, 10-7
    PubMed 25482339
  4. Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
    The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
    MAbs, 6 (4), 1038-50
    PubMed 24525727
  5. Paleos CM, Sideratou Z, Theodossiou TA, Tsiourvas D (2014)
    Carboxylated hydroxyethyl starch: a novel polysaccharide for the delivery of doxorubicin
    Chem Biol Drug Des, 85 (5), 653-8
    PubMed 25303215
  6. Repetto-Llamazares AH, Larsen RH, Giusti AM, Riccardi E, Bruland ØS, Selbo PK, Dahle J (2014)
    177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice
    PLoS One, 9 (7), e103070
    PubMed 25068508
  7. Wang F, Zamora G, Sun CH, Trinidad A, Berg K, Madsen SJ, Kwon YJ, Hirschberg H (2014)
    Photochemical internalization (PCI) enhanced nonviral transfection of tumor suppressor and pro-drug activating genes; a potential treatment modality for gliomas.
    PROC SPIE, 8928, UNSP 89280B
  8. Wang F, Zamora G, Sun CH, Trinidad A, Chun C, Kwon YJ, Berg K, Madsen SJ, Hirschberg H (2014)
    Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene
    J Neurooncol, 118 (1), 29-37
    PubMed 24610460
  9. Weyergang A, Cheung LH, Rosenblum MG, Mohamedali KA, Peng Q, Waltenberger J, Berg K (2014)
    Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
    J Control Release, 180, 1-9
    PubMed 24531010
  10. Zamora G, Wang F, Sun CH, Trinidad A, Kwon YJ, Cho SK, Berg K, Madsen SJ, Hirschberg H (2014)
    Photochemical internalization-mediated nonviral gene transfection: polyamine core-shell nanoparticles as gene carrier
    J Biomed Opt, 19 (10), 105009
    PubMed 25341069

Publications 2013

  1. Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
    Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
    J Control Release, 168 (3), 317-26
    PubMed 23567040
  2. Gaware VS, Håkerud M, Leósson K, Jónsdóttir S, Høgset A, Berg K, Másson M (2013)
    Tetraphenylporphyrin tethered chitosan based carriers for photochemical transfection
    J Med Chem, 56 (3), 807-19
    PubMed 23281854
  3. Håkerud M, Waeckerle-Men Y, Selbo PK, Kündig TM, Høgset A, Johansen P (2013)
    Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen
    J Control Release, 174, 143-50
    PubMed 24280261
  4. Olsen CE, Berg K, Selbo PK, Weyergang A (2013)
    Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin
    Free Radic Biol Med, 65, 1300-1309
    PubMed 24076428
  5. Singh R, Tønnesen HH, Kristensen S, Berg K (2013)
    The influence of Pluronics® on dark cytotoxicity, photocytotoxicity, localization and uptake of curcumin in cancer cells: studies of curcumin and curcuminoids XLIX
    Photochem Photobiol Sci, 12 (3), 559-75
    PubMed 23108412
  6. Sobczyński J, Kristensen S, Berg K (2013)
    The influence of Pluronics nanovehicles on dark cytotoxicity, photocytotoxicity and localization of four model photosensitizers in cancer cells
    Photochem Photobiol Sci, 13 (1), 8-22
    PubMed 24158176
  7. Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013)
    Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
    Biochim Biophys Acta, 1830 (8), 4235-43
    PubMed 23643966
  8. Vikdal M, Generalov R, Berg K (2013)
    The photosensitizer disulfonated aluminum phthalocyanine reduces uptake and alters trafficking of fluid phase endocytosed drugs in vascular endothelial cells--impact on efficacy of photochemical internalization
    Biochem Pharmacol, 86 (6), 748-58
    PubMed 23876343
  9. Vikdal M, Weyergang A, Selbo PK, Berg K (2013)
    Vascular endothelial cells as targets for photochemical internalization (PCI)
    Photochem Photobiol, 89 (5), 1185-92
    PubMed 23819771
  10. Waeckerle-Men Y, Mauracher A, Håkerud M, Mohanan D, Kündig TM, Høgset A, Johansen P (2013)
    Photochemical targeting of antigens to the cytosol for stimulation of MHC class-I-restricted T-cell responses
    Eur J Pharm Biopharm, 85 (1), 34-41
    PubMed 23461859
  11. Weyergang A, Selbo PK, Berg K (2013)
    Sustained ERK inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy (vol 1830, pg 2659, 2013)
    Biochim. Biophys. Acta-Gen. Subj., 1830 (10), 4417
  12. Weyergang A, Selbo PK, Berg K (2013)
    Sustained ERK [corrected] inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
    Biochim Biophys Acta, 1830 (3), 2659-70
    PubMed 23671927

Publications 2012

  1. Abu-Yousif AO, Moor AC, Zheng X, Savellano MD, Yu W, Selbo PK, Hasan T (2012)
    Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells
    Cancer Lett, 321 (2), 120-7
    PubMed 22266098
  2. Berstad MB, Weyergang A, Berg K (2012)
    Photochemical internalization (PCI) of HER2-targeted toxins: synergy is dependent on the treatment sequence
    Biochim Biophys Acta, 1820 (12), 1849-58
    PubMed 22981913
  3. Garaiova Z, Strand SP, Reitan NK, Lélu S, Størset SØ, Berg K, Malmo J, Folasire O, Bjørkøy A, Davies Cde L (2012)
    Cellular uptake of DNA-chitosan nanoparticles: the role of clathrin- and caveolae-mediated pathways
    Int J Biol Macromol, 51 (5), 1043-51
    PubMed 22947453
  4. Selbo PK, Weyergang A, Eng MS, Bostad M, Mælandsmo GM, Høgset A, Berg K (2012)
    Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug
    J Control Release, 159 (2), 197-203
    PubMed 22349185
  5. Wang JT, Berg K, Høgset A, Bown SG, MacRobert AJ (2012)
    Photophysical and photobiological properties of a sulfonated chlorin photosensitiser TPCS(2a) for photochemical internalisation (PCI)
    Photochem Photobiol Sci, 12 (3), 519-26
    PubMed 23232550

Publications 2011

  1. Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC, Golab J (2011)
    Photodynamic therapy of cancer: an update
    CA Cancer J Clin, 61 (4), 250-81
    PubMed 21617154
  2. Berg K, Golab J, Korbelik M, Russell D (2011)
    Drug delivery technologies and immunological aspects of photodynamic therapy
    Photochem Photobiol Sci, 10 (5), 647-8
    PubMed 21487635
  3. Berg K, Nordstrand S, Selbo PK, Tran DT, Angell-Petersen E, Høgset A (2011)
    Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization
    Photochem Photobiol Sci, 10 (10), 1637-51
    PubMed 21773635
  4. Jerjes WK, Upile T, Wong BJ, Betz CS, Sterenborg HJ, Witjes MJ, Berg K, van Veen R, Biel MA, El-Naggar AK, Mosse CA, Olivo M, Richards-Kortum R, Robinson DJ, Rosen J, Yodh AG, Kendall C, Ilgner JF, Amelink A, Bagnato V, Barr H, Bolotine L, Bigio I, Chen Z, Choo-Smith LP et al. (2011)
    The future of medical diagnostics: review paper
    Head Neck Oncol, 3, 38
    PubMed 21861912
  5. Upile T, Jerjes WK, Sterenborg HJ, Wong BJ, El-Naggar AK, Ilgner JF, Sandison A, Witjes MJ, Biel MA, van Veen R, Hamdoon Z, Gillenwater A, Mosse CA, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Barr H, Chen Z, Berg K, D'Cruz AK, Sudhoff H, Stone N, Kendall C et al. (2011)
    At the frontiers of surgery: review
    Head Neck Oncol, 3 (1), 7
    PubMed 21306627
  6. Weyergang A, Selbo PK, Berstad ME, Bostad M, Berg K (2011)
    Photochemical internalization of tumor-targeted protein toxins
    Lasers Surg Med, 43 (7), 721-33
    PubMed 22057500

Publications 2010

  1. Berg K, Berstad M, Prasmickaite L, Weyergang A, Selbo PK, Hedfors I, Høgset A (2010)
    Photochemical internalization: a new tool for gene and oligonucleotide delivery
    Top Curr Chem, 296, 251-81
    PubMed 21504105
  2. Berg K, Weyergang A, Prasmickaite L, Bonsted A, Høgset A, Strand MT, Wagner E, Selbo PK (2010)
    Photochemical internalization (PCI): a technology for drug delivery
    Methods Mol Biol, 635, 133-45
    PubMed 20552345
  3. Johansen P, Berg K, Selbo PK, Hofbauer GF (2010)
    [Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer]
    Praxis (Bern 1994), 99 (23), 1423-8
    PubMed 21082595
  4. Reiners JJ, Agostinis P, Berg K, Oleinick NL, Kessel D (2010)
    Assessing autophagy in the context of photodynamic therapy
    Autophagy, 6 (1), 7-18
    PubMed 19855190
  5. Selbo PK, Weyergang A, Høgset A, Norum OJ, Berstad MB, Vikdal M, Berg K (2010)
    Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules
    J Control Release, 148 (1), 2-12
    PubMed 20600406

Publications 2009

  1. Mojzisova H, Bonneau S, Maillard P, Berg K, Brault D (2009)
    Photosensitizing properties of chlorins in solution and in membrane-mimicking systems
    Photochem Photobiol Sci, 8 (6), 778-87
    PubMed 19492105
  2. Norum OJ, Bruland ØS, Gorunova L, Berg K (2009)
    Photochemical internalization of bleomycin before external-beam radiotherapy improves locoregional control in a human sarcoma model
    Int J Radiat Oncol Biol Phys, 75 (3), 878-85
    PubMed 19665318
  3. Norum OJ, Giercksky KE, Berg K (2009)
    Photochemical internalization as an adjunct to marginal surgery in a human sarcoma model
    Photochem Photobiol Sci, 8 (6), 758-62
    PubMed 19492102
  4. Norum OJ, Selbo PK, Weyergang A, Giercksky KE, Berg K (2009)
    Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
    J Photochem Photobiol B, 96 (2), 83-92
    PubMed 19467605
  5. Selbo PK, Rosenblum MG, Cheung LH, Zhang W, Berg K (2009)
    Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel
    PLoS One, 4 (8), e6691
    PubMed 19690617
  6. Upile T, Jerjes W, Sterenborg HJ, El-Naggar AK, Sandison A, Witjes MJ, Biel MA, Bigio I, Wong BJ, Gillenwater A, MacRobert AJ, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Mosse CA, Barr H, Chen Z, Berg K, D'Cruz AK, Stone N, Kendall C, Fisher S, Leunig A et al. (2009)
    Head & neck optical diagnostics: vision of the future of surgery
    Head Neck Oncol, 1, 25
    PubMed 19594907
  7. Weyergang A, Berg K, Kaalhus O, Peng Q, Selbo PK (2009)
    Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
    Mol Pharm, 6 (1), 255-64
    PubMed 19125612
  8. Woodhams J, Lou PJ, Selbo PK, Mosse A, Oukrif D, MacRobert A, Novelli M, Peng Q, Berg K, Bown SG (2009)
    Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver
    J Control Release, 142 (3), 347-53
    PubMed 19932724

Publications 2008

  1. Bonsted A, Wagner E, Prasmickaite L, Høgset A, Berg K (2008)
    Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes
    Methods Mol Biol, 434, 171-81
    PubMed 18470645
  2. Lai PS, Pai CL, Peng CL, Shieh MJ, Berg K, Lou PJ (2008)
    Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization
    J Biomed Mater Res A, 87 (1), 147-55
    PubMed 18085655
  3. Norum OJ, Gaustad JV, Angell-Petersen E, Rofstad EK, Peng Q, Giercksky KE, Berg K (2008)
    Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery
    Photochem Photobiol, 85 (3), 740-9
    PubMed 19076314
  4. Weyergang A, Kaalhus O, Berg K (2008)
    Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival
    Mol Cancer Ther, 7 (6), 1740-50
    PubMed 18566245
  5. Weyergang A, Kaalhus O, Berg K (2008)
    Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478
    Photochem Photobiol Sci, 7 (9), 1032-40
    PubMed 18754049

Publications 2007

  1. Berg K, Folini M, Prasmickaite L, Selbo PK, Bonsted A, Engesaeter BØ, Zaffaroni N, Weyergang A, Dietze A, Maelandsmo GM, Wagner E, Norum OJ, Høgset A (2007)
    Photochemical internalization: a new tool for drug delivery
    Curr Pharm Biotechnol, 8 (6), 362-72
    PubMed 18289045
  2. Folini M, Bandiera R, Millo E, Gandellini P, Sozzi G, Gasparini P, Longoni N, Binda M, Daidone MG, Berg K, Zaffaroni N (2007)
    Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells
    Cell Prolif, 40 (6), 905-20
    PubMed 18021178
  3. Madsen SJ, Kharkhuu K, Berg K, Hirschberg H (2007)
    Photochemical internalization for the treatment of malignant gliomas
    PROC SPIE, 6424, 64242C
  4. Melhus KB, Larsen RH, Stokke T, Kaalhus O, Selbo PK, Dahle J (2007)
    Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th
    Cancer Biother Radiopharm, 22 (4), 469-79
    PubMed 17803441
  5. Peng Q, Berg K (2007)
    Introduction to the special issue on photodynamic therapy and photodetection
    Photochem. Photobiol. Sci., 6 (12), 1233
  6. Weyergang A, Selbo PK, Berg K (2007)
    Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor
    Biochem Pharmacol, 74 (2), 226-35
    PubMed 17531956
  7. Yip WL, Weyergang A, Berg K, Tønnesen HH, Selbo PK (2007)
    Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
    Mol Pharm, 4 (2), 241-51
    PubMed 17263556

Publications 2006

  1. Berg K, Høgset A, Prasmickaite L, Weyergang A, Bonsted A, Dietze A, Lou PJ, Bown S, Norum OJ, Møllergard HM, Selbo PK (2006)
    Photochemical internalization (PCI): A novel technology for activation of endocytosed therapeutic agents.
    Med Laser Appl, 21, 239-251
    PublikaID 73
  2. Bonsted A, Engesaeter BØ, Høgset A, Berg K (2006)
    Photochemically enhanced adenoviral transduction in a multicellular environment
    Photochem Photobiol Sci, 5 (4), 411-21
    PubMed 16583022
  3. Bonsted A, Engesaeter BØ, Høgset A, Maelandsmo GM, Prasmickaite L, D'Oliveira C, Hennink WE, van Steenis JH, Berg K (2006)
    Photochemically enhanced transduction of polymer-complexed adenovirus targeted to the epidermal growth factor receptor
    J Gene Med, 8 (3), 286-97
    PubMed 16342300
  4. Dietze A, Selbo PK, Prasmickaite L, Weyergang A, Bonsted A, Engesaeter B, Hogset A, Berg K (2006)
    Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals
    J Environ Pathol Toxicol Oncol, 25 (1-2), 521-36
    PubMed 16566739
  5. Engesaeter BØ, Bonsted A, Lillehammer T, Engebraaten O, Berg K, Maelandsmo GM (2006)
    Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines
    Cancer Biol Ther, 5 (11), 1511-20
    PubMed 17012835
  6. Engesaeter BØ, Tveito S, Bonsted A, Engebraaten O, Berg K, Maelandsmo GM (2006)
    Photochemical treatment with endosomally localized photosensitizers enhances the number of adenoviruses in the nucleus
    J Gene Med, 8 (6), 707-18
    PubMed 16518880
  7. Henriksson CE, Hellum M, Landsverk KS, Klingenberg O, Joø GB, Kierulf P (2006)
    Flow cytometry-sorted non-viable endotoxin-treated human monocytes are strongly procoagulant
    Thromb Haemost, 96 (1), 29-37
    PubMed 16807648
  8. Henriksson CE, Klingenberg O, Hellum M, Landsverk KS, Joø GB, Westvik AB, Kierulf P (2006)
    Calcium ionophore-induced de-encryption of tissue factor in monocytes is associated with extensive cell death
    Thromb Res, 119 (5), 621-30
    PubMed 16844202
  9. Kloeckner J, Boeckle S, Persson D, Roedl W, Ogris M, Berg K, Wagner E (2006)
    DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions
    J Control Release, 116 (2), 115-22
    PubMed 16959361
  10. Lou PJ, Lai PS, Shieh MJ, Macrobert AJ, Berg K, Bown SG (2006)
    Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization
    Int J Cancer, 119 (11), 2692-8
    PubMed 16991130
  11. Ndoye A, Dolivet G, Høgset A, Leroux A, Fifre A, Erbacher P, Berg K, Behr JP, Guillemin F, Merlin JL (2006)
    Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization
    Mol Ther, 13 (6), 1156-62
    PubMed 16564229
  12. Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
    Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
    FEBS Lett, 580 (24), 5739-46
    PubMed 17007842
  13. Prasmickaite L, Hellum M, Kaalhus O, Høgset A, Wagner E, Berg K (2006)
    Photochemical internalization of transgenes controlled by the heat-shock protein 70 promoter
    Photochem Photobiol, 82 (3), 809-16
    PubMed 16420102
  14. Selbo PK, Weyergang A, Bonsted A, Bown SG, Berg K (2006)
    Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells
    J Pharmacol Exp Ther, 319 (2), 604-12
    PubMed 16902053
  15. Solban N, Selbo PK, Sinha AK, Chang SK, Hasan T (2006)
    Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer
    Cancer Res, 66 (11), 5633-40
    PubMed 16740700
  16. Weyergang A, Selbo PK, Berg K (2006)
    Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
    J Control Release, 111 (1-2), 165-73
    PubMed 16466823

Publications 2005

  1. Berg K, Dietze A, Kaalhus O, Høgset A (2005)
    Site-specific drug delivery by photochemical internalization enhances the antitumor effect of bleomycin
    Clin Cancer Res, 11 (23), 8476-85
    PubMed 16322311
  2. Berg K, Selbo PK, Weyergang A, Dietze A, Prasmickaite L, Bonsted A, Engesaeter BØ, Angell-Petersen E, Warloe T, Frandsen N, Høgset A (2005)
    Porphyrin-related photosensitizers for cancer imaging and therapeutic applications
    J Microsc, 218 (Pt 2), 133-47
    PubMed 15857375
  3. Bonsted A, Høgset A, Hoover F, Berg K (2005)
    Photochemical enhancement of gene delivery to glioblastoma cells is dependent on the vector applied
    Anticancer Res, 25 (1A), 291-7
    PubMed 15816550
  4. Dietze A, Berg K (2005)
    ALA-induced porphyrin formation and fluorescence in synovitis tissue In-vitro and in vivo studies
    Photodiagnosis Photodyn Ther, 2 (4), 299-307
    PubMed 25048871
  5. Dietze A, Peng Q, Selbo PK, Kaalhus O, Müller C, Bown S, Berg K (2005)
    Enhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin
    Br J Cancer, 92 (11), 2004-9
    PubMed 15886704
  6. Engesaeter BØ, Bonsted A, Berg K, Høgset A, Engebråten O, Fodstad Ø, Curiel DT, Maelandsmo GM (2005)
    PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles
    Cancer Gene Ther, 12 (5), 439-48
    PubMed 15678152
  7. Gederaas OA, Schønberg SA, Ramstad S, Berg K, Johnsson A, Krokan HE (2005)
    Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization
    Photochem Photobiol Sci, 4 (4), 383-9
    PubMed 15803209

Publications 2004

  1. Berg K, Selbo PK, Prasmickaite L, Høgset A (2004)
    Photochemical drug and gene delivery
    Curr Opin Mol Ther, 6 (3), 279-87
    PubMed 15264430
  2. Bonsted A, Engesaeter BØ, Høgset A, Maelandsmo GM, Prasmickaite L, Kaalhus O, Berg K (2004)
    Transgene expression is increased by photochemically mediated transduction of polycation-complexed adenoviruses
    Gene Ther, 11 (2), 152-60
    PubMed 14712299
  3. Høgset A, Prasmickaite L, Selbo PK, Hellum M, Engesaeter BØ, Bonsted A, Berg K (2004)
    Photochemical internalisation in drug and gene delivery
    Adv Drug Deliv Rev, 56 (1), 95-115
    PubMed 14706447
  4. Kloeckner J, Prasmickaite L, Høgset A, Berg K, Wagner E (2004)
    Photochemically enhanced gene delivery of EGF receptor-targeted DNA polyplexes
    J Drug Target, 12 (4), 205-13
    PubMed 15506169
  5. Ndoye A, Bouali S, Dolivet G, Leroux A, Erbacher P, Behr JP, Berg K, Guillemin F, Merlin JL (2004)
    Sustained gene transfer and enhanced cell death following glucosylated-PEI-mediated p53 gene transfer with photochemical internalisation in p53-mutated head and neck carcinoma cells
    Int J Oncol, 25 (6), 1575-81
    PubMed 15547693
  6. Ndoye A, Merlin JL, Leroux A, Dolivet G, Erbacher P, Behr JP, Berg K, Guillemin F (2004)
    Enhanced gene transfer and cell death following p53 gene transfer using photochemical internalisation of glucosylated PEI-DNA complexes
    J Gene Med, 6 (8), 884-94
    PubMed 15293347
  7. Prasmickaite L, Høgset A, Engesaeter B BØ, Bonsted A, Berg K (2004)
    Light-directed gene delivery by photochemical internalisation
    Expert Opin Biol Ther, 4 (9), 1403-12
    PubMed 15335308
  8. Prasmickaite L, Høgset A, Olsen VM, Kaalhus O, Mikalsen SO, Berg K (2004)
    Photochemically enhanced gene transfection increases the cytotoxicity of the herpes simplex virus thymidine kinase gene combined with ganciclovir
    Cancer Gene Ther, 11 (7), 514-23
    PubMed 15118758

Publications 2003

  1. Berg K, Prasmickaite L, Selbo PK, Hellum M, Bonsted A, Høgset A (2003)
    Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles
    Oftalmologia, 56 (1), 67-71
    PubMed 12886687
  2. Dietze A, Bonsted A, Høgset A, Berg K (2003)
    Photochemical internalization enhances the cytotoxic effect of the protein toxin gelonin and transgene expression in sarcoma cells
    Photochem Photobiol, 78 (3), 283-9
    PubMed 14556316
  3. Folini M, Berg K, Millo E, Villa R, Prasmickaite L, Daidone MG, Benatti U, Zaffaroni N (2003)
    Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase
    Cancer Res, 63 (13), 3490-4
    PubMed 12839932
  4. Hellum M, Høgset A, Engesaeter BO, Prasmickaite L, Stokke T, Wheeler C, Berg K (2003)
    Photochemically enhanced gene delivery with cationic lipid formulations
    Photochem Photobiol Sci, 2 (4), 407-11
    PubMed 12760539
  5. Høgset A, Prasmickaite L, Engesaeter BO, Hellum M, Selbo PK, Olsen VM, Maelandsmo GM, Berg K (2003)
    Light directed gene transfer by photochemical internalisation
    Curr Gene Ther, 3 (2), 89-112
    PubMed 12653404

Publications 2002

  1. Høgset A, Engesaeter BO, Prasmickaite L, Berg K, Fodstad O, Maelandsmo GM (2002)
    Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy
    Cancer Gene Ther, 9 (4), 365-71
    PubMed 11960287
  2. Høgset A, Prasmickaite L, Hellum M, Engesaeter BO, Olsen VM, Tjelle TE, Wheeler CJ, Berg K (2002)
    Photochemical transfection: a technology for efficient light-directed gene delivery
    Somat Cell Mol Genet, 27 (1-6), 97-113
    PubMed 12774944
  3. Prasmickaite L, Høgset A, Berg K (2002)
    The role of the cell cycle on the efficiency of photochemical gene transfection
    Biochim Biophys Acta, 1570 (3), 210-8
    PubMed 12020812
  4. Prasmickaite L, Høgset A, Berg K (2002)
    Photochemical transfection. Light-induced, site-directed gene delivery
    Methods Mol Med, 69, 123-35
    PubMed 11987772
  5. Prasmickaite L, Høgset A, Selbo PK, Engesaeter BØ, Hellum M, Berg K (2002)
    Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy
    Br J Cancer, 86 (4), 652-7
    PubMed 11870551
  6. Selbo PK, Høgset A, Prasmickaite L, Berg K (2002)
    Photochemical internalisation: a novel drug delivery system
    Tumour Biol, 23 (2), 103-12
    PubMed 12065848
 
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