Publications by Kjetil Wessel Andressen

33 publications found

  1. Faleeva M, Diakonov I, Srivastava P, Ramuz M, Calamera G, Andressen KW, Bork N, Tsansizi L, Cosson MV, Bernardo AS, Nikolaev V, Gorelik J (2022)
    Compartmentation of cGMP Signaling in Induced Pluripotent Stem Cell Derived Cardiomyocytes during Prolonged Culture
    Cells, 11 (20)
    DOI 10.3390/cells11203257, PubMed 36291124
  2. Calamera G, Moltzau LR, Levy FO, Andressen KW (2022)
    Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
    Int J Mol Sci, 23 (4)
    DOI 10.3390/ijms23042145, PubMed 35216259
  3. Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW (2022)
    CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
    Cardiovasc Res, 118 (6), 1506-1519
    DOI 10.1093/cvr/cvab167, PubMed 33970224
  4. Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
    Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
    Front Cardiovasc Med, 7, 623922
    DOI 10.3389/fcvm.2020.623922, PubMed 33569394
  5. Jang W, Adams CE, Liu H, Zhang C, Levy FO, Andressen KW, Lambert NA (2020)
    An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling
    Proc Natl Acad Sci U S A, 117 (48), 30755-30762
    DOI 10.1073/pnas.2010801117, PubMed 33199589
  6. Calamera G, Li D, Ulsund AH, Kim JJ, Neely OC, Moltzau LR, Bjørnerem M, Paterson D, Kim C, Levy FO, Andressen KW (2019)
    FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons
    Commun Biol, 2, 394
    DOI 10.1038/s42003-019-0641-x, PubMed 31701023
  7. Ulsund AH, Dahl M, Frimurer TM, Manfra O, Schwartz TW, Levy FO, Andressen KW (2018)
    Preassociation between the 5-HT7 serotonin receptor and G protein Gs: molecular determinants and association with low potency activation of adenylyl cyclase
    FASEB J, 33 (3), 3870-3886
    DOI 10.1096/fj.201800805RR, PubMed 30508496
  8. Andressen KW, Ulsund AH, Krobert KA, Lohse MJ, Bünemann M, Levy FO (2018)
    Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gαs upon receptor activation
    FASEB J, 32 (2), 1059-1069
    DOI 10.1096/fj.201700486R, PubMed 29079700
  9. Todd Milne G, on behalf of the Ironwood team, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, Andresen H, Moltzau LR, Cataliotti A, Levy FO, Lukowski R, Frankenreiter S, Friebe A, Calamaras T, Baumgartner R et al. (2017)
    Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017
    BMC Pharmacol Toxicol, 18 (Suppl 1), 64
    DOI 10.1186/s40360-017-0170-5, PubMed 29035170
  10. Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
    PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
    Eur J Pharmacol, 812, 174-183
    DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992
  11. Olberg DE, Bauer N, Andressen KW, Hjørnevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2016)
    Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats
    Nucl Med Biol, 43 (8), 478-89
    DOI 10.1016/j.nucmedbio.2016.05.003, PubMed 27236283
  12. Impellizzeri AA, Pappalardo M, Basile L, Manfra O, Andressen KW, Krobert KA, Messina A, Levy FO, Guccione S (2015)
    Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis
    Front Behav Neurosci, 9, 92
    DOI 10.3389/fnbeh.2015.00092, PubMed 26005408
  13. Andressen KW, Manfra O, Brevik CH, Ulsund AH, Vanhoenacker P, Levy FO, Krobert KA (2015)
    The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors
    Br J Pharmacol, 172 (15), 3846-60
    DOI 10.1111/bph.13169, PubMed 25884989
  14. Ørstavik Ø, Manfra O, Andressen KW, Andersen GØ, Skomedal T, Osnes JB, Levy FO, Krobert KA (2015)
    The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium
    PLoS One, 10 (3), e0115547
    DOI 10.1371/journal.pone.0115547, PubMed 25738589
  15. Manfra O, Van Craenenbroeck K, Skieterska K, Frimurer T, Schwartz TW, Levy FO, Andressen KW (2015)
    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
    ACS Chem Neurosci, 6 (7), 1206-18
    DOI 10.1021/cn500339p, PubMed 25706089
  16. Brudeli B, Navaratnarajah M, Andressen KW, Manfra O, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2014)
    Discovery and pharmacological profile of new hydrophilic 5-HT(4) receptor antagonists
    Bioorg Med Chem Lett, 24 (18), 4598-4602
    DOI 10.1016/j.bmcl.2014.06.083, PubMed 25149506
  17. Olberg DE, Andressen KW, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2014)
    Synthesis and in vitro evaluation of small-molecule [18F] labeled gonadotropin-releasing hormone (GnRH) receptor antagonists as potential PET imaging agents for GnRH receptor expression
    Bioorg Med Chem Lett, 24 (7), 1846-50
    DOI 10.1016/j.bmcl.2014.02.002, PubMed 24613701
  18. Kilander MB, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G (2014)
    Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6
    FASEB J, 28 (5), 2293-305
    DOI 10.1096/fj.13-246363, PubMed 24500924
  19. Brudeli B, Andressen KW, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2013)
    Acidic biphenyl derivatives: synthesis and biological activity of a new series of potent 5-HT(4) receptor antagonists
    Bioorg Med Chem, 21 (22), 7134-45
    DOI 10.1016/j.bmc.2013.09.004, PubMed 24113240
  20. Gellynck E, Heyninck K, Andressen KW, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2013)
    The serotonin 5-HT7 receptors: two decades of research
    Exp Brain Res, 230 (4), 555-68
    DOI 10.1007/s00221-013-3694-y, PubMed 24042216
  21. Brudeli B, Moltzau LR, Nguyen CH, Andressen KW, Nilsen NO, Levy FO, Klaveness J (2013)
    Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
    Eur J Med Chem, 64, 629-37
    DOI 10.1016/j.ejmech.2013.03.060, PubMed 23711770
  22. Gellynck E, Andressen KW, Lintermans B, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2012)
    Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT₇a receptor
    FEBS J, 279 (11), 1994-2003
    DOI 10.1111/j.1742-4658.2012.08581.x, PubMed 22448645
  23. Brudeli B, Moltzau LR, Andressen KW, Krobert KA, Klaveness J, Levy FO (2010)
    Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
    Bioorg Med Chem, 18 (24), 8600-13
    DOI 10.1016/j.bmc.2010.10.011, PubMed 21075638
  24. Ngai J, Methi T, Andressen KW, Levy FO, Torgersen KM, Vang T, Wettschureck N, Taskén K (2008)
    The heterotrimeric G-protein alpha-subunit Galphaq regulates TCR-mediated immune responses through an Lck-dependent pathway
    Eur J Immunol, 38 (11), 3208-18
    DOI 10.1002/eji.200838195, PubMed 18991294
  25. Afzal F, Andressen KW, Mørk HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E (2008)
    5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
    Br J Pharmacol, 155 (7), 1005-14
    DOI 10.1038/bjp.2008.339, PubMed 18846035
  26. Gellynck E, Laenen K, Andressen KW, Lintermans B, De Martelaere K, Matthys A, Levy FO, Haegeman G, Vanhoenacker P, Van Craenenbroeck K (2008)
    Cloning, genomic organization and functionality of 5-HT(7) receptor splice variants from mouse brain
    Gene, 426 (1-2), 23-31
    DOI 10.1016/j.gene.2008.08.011, PubMed 18793707
  27. Vinge LE, Andressen KW, Attramadal T, Andersen GØ, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H (2007)
    Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
    Mol Pharmacol, 72 (3), 582-91
    DOI 10.1124/mol.107.035766, PubMed 17573483
  28. Krobert KA, Andressen KW, Levy FO (2006)
    Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor
    Eur J Pharmacol, 532 (1-2), 1-10
    DOI 10.1016/j.ejphar.2005.11.039, PubMed 16487959
  29. Andressen KW, Norum JH, Levy FO, Krobert KA (2005)
    Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT(7) receptor expression
    Mol Pharmacol, 69 (1), 207-15
    DOI 10.1124/mol.105.015396, PubMed 16189297
  30. Qvigstad E, Brattelid T, Sjaastad I, Andressen KW, Krobert KA, Birkeland JA, Sejersted OM, Kaumann AJ, Skomedal T, Osnes JB, Levy FO (2005)
    Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
    Cardiovasc Res, 65 (4), 869-78
    DOI 10.1016/j.cardiores.2004.11.017, PubMed 15721867
  31. Brattelid T, Kvingedal AM, Krobert KA, Andressen KW, Bach T, Hystad ME, Kaumann AJ, Levy FO (2004)
    Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i)
    Naunyn Schmiedebergs Arch Pharmacol, 369 (6), 616-28
    DOI 10.1007/s00210-004-0919-4, PubMed 15118808
  32. Bruheim S, Krobert KA, Andressen KW, Levy FO (2003)
    Unaltered agonist potency upon inducible 5-HT7(a) but not 5-HT4(b) receptor expression indicates agonist-independent association of 5-HT7(a) receptor and Gs
    Recept Channels, 9 (2), 107-16
    DOI 10.1080/10606820308245, PubMed 12916471
  33. Olberg DE, Hausner SH, Bauer N, Klaveness J, Indrevoll B, Andressen KW, Dahl M, Levy FO, Sutcliffe JL, Haraldsen I (2015)
    Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats
    MedChemComm, 6 (4), 708-714
    DOI 10.1039/c4md00486h

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