Stefan Krauss' group

Cell signalling research group

Stefan Krauss

Since its discovery in 1993 (Krauss et al., Cell 75, 1431-1444) Shh has shown to be a central signal in numerous developmental systems. The laboratory for cell signalling focuses on Hh and Wnt/beta-catenin signalling in development, stem cells, and tumors. The laboratory currently works on pathways that feed into Hh and Wnt/beta-catenin signaling. Using chemical biology, the laboratory develops novel Hh and Wnt/beta-catenin.

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News & events

A newly identified protein regulates cell division
May 21, 2013

The story of PCI popularized and presented in national media
May 14, 2013

Publication in Nature Genetics on testicular cancer susceptibility
May 13, 2013

Institute seminar May 8th
Gunnar Kvalheim
May 6, 2013

Llorente and coworkers publish detailed lipidomic analyses of exosomes released from prostate cancer cells
May 2, 2013

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Latest articles

Cell signalling research group

Klimova L, Lachova J, Machon O, Sedlacek R, Kozmik Z (2013)
Generation of mRx-Cre Transgenic Mouse Line for Efficient Conditional Gene Deletion in Early Retinal Progenitors
PLoS One, 8 (5), e63029
PubMed 23667567

Lehtiö L, Chi NW, Krauss S
Tankyrases as Drug Targets
FEBS J (in press)
PubMed 23648170

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M (2013)
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation-Driven Colorectal Tumor Growth
Cancer Res, 73 (10), 3132-3144
PubMed 23539443

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