Stefan Krauss' group

Cell signalling research group

Since its discovery in 1993 (Krauss et al., Cell 75, 1431-1444) Shh has shown to be a central signal in numerous developmental systems. The laboratory for cell signalling focuses on Hh and Wnt/beta-catenin signalling in development, stem cells, and tumors. The laboratory currently works on pathways that feed into Hh and Wnt/beta-catenin signaling. Using chemical biology, the laboratory develops novel Hh and Wnt/beta-catenin.

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News & events

Gordon Research Conference awards to Haugsten and Zakrzewska
May 22, 2012

Institute Seminar - Wednesday May 23rd
Giske Ursin
May 22, 2012

Understanding breast cancer
Landscape of cancer genes and mutational processes in breast cancer
May 21, 2012

Untangling the development of breast cancer
Researchers announce the first comprehensive genome studies of the evolution of 21 breast cancers
May 18, 2012

Presentation of prestigious research project
Actionable Targets in Cancer Metastasis (MetAction) – from Bed to Bench to Byte to Bedside
May 16, 2012

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Latest articles

Cell signalling research group

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S
A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Cancer Res (in press)
PubMed 22440753

Roberg-Larsen H, Strand MF, Grimsmo A, Olsen PA, Dembinski JL, Rise F, Lundanes E, Greibrokk T, Krauss S, Wilson SR
High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry
J Chromatogr A (in press)
PubMed 22410154

Solberg N, Machon O, Machonova O, Krauss S (2012)
Mouse Tcf3 represses canonical Wnt signaling by either competing for ?-catenin binding or through occupation of DNA-binding sites
Mol Cell Biochem, 365 (1-2), 53-63
PubMed 22270545

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