Author network for Antoni Wiedlocha by COREMINE medical

Publications 2011

Jin Y, Zhen Y, Haugsten EM, Wiedlocha A (2011)
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
Cell Signal, 23 (11), 1758-66
PubMed 21745565

Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
PubMed 21223966

Publications 2010

Haugsten EM, Wiedlocha A, Olsnes S, Wesche J (2010)
Roles of fibroblast growth factor receptors in carcinogenesis
Mol Cancer Res, 8 (11), 1439-52
PubMed 21047773

Publications 2009

Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S (2009)
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
J Biol Chem, 284 (37), 25388-403
PubMed 19574212

Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J (2009)
Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
Biochemistry, 48 (30), 7209-18
PubMed 19558187

Publications 2008

Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
PubMed 18411303

Zakrzewska M, Marcinkowska E, Wiedlocha A (2008)
FGF-1: from biology through engineering to potential medical applications
Crit Rev Clin Lab Sci, 45 (1), 91-135
PubMed 18293181

Publications 2007

Nilsen T, Rosendal KR, Sørensen V, Wesche J, Olsnes S, Wied?ocha A (2007)
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
J Biol Chem, 282 (36), 26245-56
PubMed 17616529

Zhen Y, Sørensen V, Jin Y, Suo Z, Wied?ocha A (2007)
Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
Oncogene, 26 (44), 6372-85
PubMed 17533378

Publications 2006

Marcinkowska E, Superat K, Wied?ocha A (2006)
FGF-1 as a possible carrier for targeted drug delivery
Oncol Res, 16 (1), 27-34
PubMed 16783965

Sørensen V, Nilsen T, Wied?ocha A (2006)
Functional diversity of FGF-2 isoforms by intracellular sorting
Bioessays, 28 (5), 504-14
PubMed 16615083

Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
PubMed 17003104

Wesche J, Ma?ecki J, Wied?ocha A, Skjerpen CS, Claus P, Olsnes S (2006)
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
PubMed 16495214

Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2006)
Structural requirements of FGF-1 for receptor binding and translocation into cells
Biochemistry, 45 (51), 15338-48
PubMed 17176056

Publications 2005

Wesche J, Ma?ecki J, Wied?ocha A, Ehsani M, Marcinkowska E, Nilsen T, Olsnes S (2005)
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
PubMed 15835896

Wied?ocha A, Nilsen T, Wesche J, Sørensen V, Ma?ecki J, Marcinkowska E, Olsnes S (2005)
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
PubMed 15574884

Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2005)
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
J Mol Biol, 352 (4), 860-75
PubMed 16126225

Publications 2004

Ma?ecki J, Wesche J, Skjerpen CS, Wied?ocha A, Olsnes S (2004)
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
Mol Biol Cell, 15 (2), 801-14
PubMed 14657241

Wied?ocha A, Sørensen V (2004)
Signaling, internalization, and intracellular activity of fibroblast growth factor
Curr Top Microbiol Immunol, 286, 45-79
PubMed 15645710

Zakrzewska M, Krowarsch D, Wiedlocha A, Otlewski J (2004)
Design of fully active FGF-1 variants with increased stability
Protein Eng Des Sel, 17 (8), 603-11
PubMed 15469994

Publications 2003

Dus D, Krawczenko A, Zalecki P, Paprocka M, Wiedlocha A, Goupille C, Kieda C (2003)
IL-7 receptor is present on human microvascular endothelial cells
Immunol. Lett., 86 (2), 163-168

Du? D, Krawczenko A, Za?ecki P, Paprocka M, Wied?ocha A, Goupille C, Kieda C (2003)
IL-7 receptor is present on human microvascular endothelial cells
Immunol Lett, 86 (2), 163-8
PubMed 12644318

Marcinkowska E, Wiedlocha A (2003)
Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
Anticancer Res, 23 (5A), 4071-7
PubMed 14666721

Olsnes S, Klingenberg O, Wied?ocha A (2003)
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
PubMed 12506129

Publications 2002

Ma?ecki J, Wied?ocha A, Wesche J, Olsnes S (2002)
Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1
EMBO J, 21 (17), 4480-90
PubMed 12198150

Marcinkowska E, Wied?ocha A (2002)
Steroid signal transduction activated at the cell membrane: from plants to animals
Acta Biochim Pol, 49 (3), 735-45
PubMed 12422243

Wabakken T, Hauge H, Finne EF, Wiedlocha A, Aasheim H (2002)
Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase
Scand J Immunol, 56 (2), 195-203
PubMed 12121439

Publications 2001

Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wied?ocha A, Olsnes S (2001)
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
PubMed 11398757

Loukianov EV, Wiedlocha A, Olsnes S, Kozlov YV (2001)
Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
Mol. Biol., 35 (1), 122-129

Marcinkowska E, Chrobak A, Wied?ocha A (2001)
Evading apoptosis by calcitriol-differentiated human leukemic HL-60 cells is not mediated by changes in CD95 receptor system but by increased sensitivity of these cells to insulin
Exp Cell Res, 270 (1), 119-27
PubMed 11597134

Publications 2000

Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
PubMed 10769213

Wesche J, Wied?ocha A, Falnes PO, Choe S, Olsnes S (2000)
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
PubMed 11106487

Publications 1999

Klingenberg O, Wiedlocha A, Olsnes S (1999)
Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
J Biol Chem, 274 (25), 18081-6
PubMed 10364261

Wied?ocha A (1999)
Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
PubMed 10604235

Wied?ocha A (1999)
[Activation of the cell proliferation program by acidic fibroblast growth factor (aFGF)]
Postepy Hig Med Dosw, 53 (2), 277-89
PubMed 10355293

Publications 1998

Kolpakova E, Wied?ocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1), 213-22
PubMed 9806903

Loukianov EV, Loukianova T, Wiedlocha A, Olsnes S (1998)
Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
Gene, 212 (1), 1-4
PubMed 9661657

Marcinkowska E, Wiedlocha A, Radzikowski C (1998)
Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
Anticancer Res, 18 (5A), 3507-14
PubMed 9858932

Wied?ocha A (1998)
Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
PubMed 9883312

Zalecki P, Radzikowski C, Olsnes S, Wied?ocha A (1998)
Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
Exp Cell Res, 244 (1), 61-70
PubMed 9770349

Publications 1997

Loukianov E, Loukianova T, Wiedlocha A, Olsnes S (1997)
Expression of mRNA for a short form of heparin-binding EGF-like growth factor
Gene, 195 (1), 81-6
PubMed 9300824

Marcinkowska E, Wied?ocha A, Radzikowski C (1997)
1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
Biochem Biophys Res Commun, 241 (2), 419-26
PubMed 9425286

Muñoz R, Klingenberg O, Wied?ocha A, Rapak A, Falnes PO, Olsnes S (1997)
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
PubMed 9247306

Wied?ocha A (1997)
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
PubMed 9437495

Publications 1996

Wied?ocha A (1996)
Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
PubMed 9017159

Wied?ocha A, Falnes PO, Rapak A, Muñoz R, Klingenberg O, Olsnes S (1996)
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
PubMed 8524304

Publications 1995

Falnes PO, Wied?ocha A, Rapak A, Olsnes S (1995)
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
Biochemistry, 34 (35), 11152-9
PubMed 7669773

Wied?ocha A, Falnes PO, Rapak A, Klingenberg O, Muñoz R, Olsnes S (1995)
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
PubMed 8530506

Publications 1994

Madshus IH, Wiedlocha A, Sandvig K (1994)
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447

Wied?ocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
PubMed 7511061

Publications 1992

Jonas L, Walzel H, Bremer H, Wiedlocha A (1992)
Comparative studies on internalization of gold labelled mistletoe lectin I (MLI), its subunits, and of an immunotoxin into mouse L 1210V leukemia cells
Acta Histochem, 92 (1), 46-53
PubMed 1580141

Paprocka M, Wied?ocha A, Walzel H, Radzikowski C (1992)
The activity of two immunotoxins composed of monoclonal antibody MoAb-16 and A-chain of ricin (MoAb-16-RTA) or A-chain of mistletoe lectin I (MoAb-16-MLIA)
Arch Immunol Ther Exp (Warsz), 40 (3-4), 223-7
PubMed 1300987

Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S (1992)
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
EMBO J, 11 (13), 4835-42
PubMed 1281450

Publications 1991

Wied?ocha A, Paprocka M, Radzikowski C (1991)
Immunomagnetic removal of L1210V leukemic cells from mouse bone marrow ex vivo
Arch Immunol Ther Exp (Warsz), 39 (3), 235-41
PubMed 1810216

Wied?ocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131

Publications 1990

Paprocka M, Wiedlocha A, Radzikowski C (1990)
Mouse L1210V leukemia as a model to analyse efficiency of leukemic cell elimination by immunotoxin, antibody and complement, and cytostatic agents
In Vivo, 4 (3), 209-13
PubMed 2133264

Publications 1989

Katnik I, Steuden I, Pupek M, Wied?ocha A, Dobryszycka W (1989)
Monoclonal antibodies against human haptoglobin
Hybridoma, 8 (5), 551-60
PubMed 2478448

Radzikowski CZ, Steuden I, Wiedlocha A, Kieler J, Tromholt V (1989)
The Thomsen-Friedenreich antigen on human urothelial cell lines detectable by peanut lectin and monoclonal antibody raised against human glycophorin A
Anticancer Res, 9 (1), 103-7
PubMed 2650614

Wied?ocha A, Salwa J, Paprocka M, Steuden I, Radzikowski C (1989)
Specific killing of mouse leukemic cells with ricin A-chain immunotoxin
Arch Immunol Ther Exp (Warsz), 37 (1-2), 101-13
PubMed 2619494

Publications 1988

Czerwi?ski M, Wa?niowska K, Steuden I, Duk M, Wied?ocha A, Lisowska E (1988)
Degradation of the human erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3
Eur J Biochem, 174 (4), 647-54
PubMed 2455637

Wa?niowska K, Duk M, Steuden I, Czerwi?ski M, Wied?ocha A, Lisowska E (1988)
Two monoclonal antibodies recognizing different epitopes of blood group N antigen
Arch Immunol Ther Exp (Warsz), 36 (5), 623-32
PubMed 2478103