Håvard Homberset
Position: Principal engineer, M.Sc
Phone: +47 23079035
Email:

I am a research technician working with a variety of the projects in the Genome Dynamics group, in addition to trying to keep the lab running as smoothly as possible. My main methodological focus is cloning, purification and characterization of recombinant proteins. The characterization involves sometimes structural studies as well as protein interactions and enzyme activities. I’m currently involved in projects on DNA repair in Mycobacterium tuberculosis and Neisseria meningitidis and in projects studying the mechanisms for horizontal gene transfer in Neisseria meningitidis.

 

Author network for Håvard Homberset by COREMINE medical


Publications 2016

Beyene GT, Balasingham SV, Frye SA, Namouchi A, Homberset H, Kalayou S, Riaz T, Tønjum T (2016)
Characterization of the Neisseria meningitidis Helicase RecG
PLoS One, 11 (10), e0164588
PubMed 27736945

Publications 2015

Frye SA, Lång E, Beyene GT, Balasingham SV, Homberset H, Rowe AD, Ambur OH, Tønjum T (2015)
The Inner Membrane Protein PilG Interacts with DNA and the Secretin PilQ in Transformation
PLoS One, 10 (8), e0134954
PubMed 26248334

Publications 2013

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Kristiansen PE, Tønjum T (2013)
Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity
Microbiology, 160 (Pt 1), 217-27
PubMed 24169816

Publications 2012

Balasingham SV, Zegeye ED, Homberset H, Rossi ML, Laerdahl JK, Bohr VA, Tønjum T (2012)
Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB
PLoS One, 7 (5), e36960
PubMed 22615856

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Tønjum T (2012)
Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
Microbiology, 158 (Pt 8), 1982-93
PubMed 22628485

Publications 2009

Lång E, Haugen K, Fleckenstein B, Homberset H, Frye SA, Ambur OH, Tønjum T (2009)
Identification of neisserial DNA binding components
Microbiology, 155 (Pt 3), 852-62
PubMed 19246756

Tibballs KL, Ambur OH, Alfsnes K, Homberset H, Frye SA, Davidsen T, Tønjum T (2009)
Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair
BMC Microbiol, 9, 7
PubMed 19134198

Publications 2007

Balasingham SV, Collins RF, Assalkhou R, Homberset H, Frye SA, Derrick JP, Tønjum T (2007)
Interactions between the lipoprotein PilP and the secretin PilQ in Neisseria meningitidis
J Bacteriol, 189 (15), 5716-27
PubMed 17526700

Publications 2006

Golovanov AP, Balasingham S, Tzitzilonis C, Goult BT, Lian LY, Homberset H, Tønjum T, Derrick JP (2006)
The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold
J Mol Biol, 364 (2), 186-95
PubMed 17007878

Golovanov AP, Balasingham S, Tzitzilonis C, Goult BT, Lian LY, Homberset H, Tønjum T, Derrick JP (2006)
Assignment of 1H, 13C, and 15N resonances for the PilP pilot protein from Neisseria meningitidis
J Biomol NMR, 36 Suppl 1, 68
PubMed 16933020