Welcome to Per Medbøe Thorsby's research group:

Biochemical endocrinology and metabolism research group

 
Group leader<br>Per M. Thorsby
Group leader
Per M. Thorsby

The aim of this research group is to explore metabolic aberrations in endocrine diseases for the identification and validation of new biomarkers.

Endocrine and metabolic diseases such as diabetes, thyroid diseases, adrenal diseases and osteoporosis are major causes of morbidity and mortality. The challenges are to identify persons at risk, implement therapeutic and preventive measures and monitor effects of these actions. Adequate diagnostics and follow-up of treatment depend heavily on biomarkers in blood, urine, tears and saliva. The aim of this research group is to explore metabolic aberrations in endocrine diseases for the identification and validation of new biomarkers by the use of transcriptomic, proteomic and metabolomic approaches in close collaboration with the Dept of Endocrinology, OUS. 

 
 

Research projects

 
  • Metabolomic profiling of hypertrophic cardiomyopathy
  • Proteomic profiling of vitamin D stimulated insulin producing cells
  • Proteomic profiling of glucose stimulated insulin producing cells
  • Gene expression of vitamin D stimulated insulin producing cells
  • Biomarkers of type 1 and 2 diabetes
  • Posttranslational modification of proteins and late complications of diabetes
  • Proteomic profiling of tear fluid in Graves ophthalmopathy
  • Prospective evaluation of biomarkers of tear fluid in Graves ophthalmopathy
  • Autoimmunity in thyroid disease
  • Proteomic profiling of CSF in narcolepsy
  • Influence of estrogen supplementations on cortisol measurements in humans
  • Steroid profiling in congenital adrenal hyperplasia
 
 
 

Contact information
Per Medbøe Thorsby, Hormone Laboratory, Department of Medical Biochemistry, 
Tel: + 47 23 03 30 43/ + 47 22 89 47 08 E-mail: pertho@ous-hf.no