Welcome to Per Medbøe Thorsby's research group:

Biochemical endocrinology and metabolism research group

Group leader
Per M. Thorsby

The aim of this research group is to explore metabolic aberrations in endocrine diseases for the identification and validation of new biomarkers.

Background

Endocrine and metabolic diseases such as diabetes, thyroid diseases, adrenal diseases and osteoporosis are major causes of morbidity and mortality.

The challenges are to identify persons at risk, implement therapeutic and preventive measures and monitor effects of these actions.

Adequate diagnostics and follow-up of treatment depend heavily on biomarkers in blood, urine, tears and saliva.

We use transcriptomic, proteomic and metabolomic approaches in close collaboration with the Dept of Endocrinology, OUS.

Research projects

Finding new biomarkers

  • Diabetes
    • Proteomic / metabolomic profiling of human insulin producing cells aiming at discovering biomarkers for cell mas / function
    • Metabolomic profiling of hyperglycemic clamp in humans
  • Thyroid disease:
    • Prospective evaluation of biomarkers of tear fluid in Graves ophtalmopathy
    • Metabolomic profiling of tear fluid in Graves ophtalmopathy
  • Adrenal disease:
    • Steroid profiling in congenital adrenal hyperplasia and PCOS

Other studies

  • Proteomic profiling of CSF in narcolepsy
  • Proteomic profiling of tear fluid in eye diseases
  • Gene expression of vitamin D stimulated human insulin producing cells

Contact information

Group Leader Per Medbøe Thorsby, MD, PhD, Ass. Prof. (HIOA)
Hormone Laboratory, Department of Medical Biochemistry
Tel: + 47 23 03 30 43/ + 47 22 89 47 08