Welcome to Per Medbøe Thorsby's research group: Biochemical endocrinology and metabolism research group

Group leaderPer M. Thorsby
Group leader
Per M. Thorsby
The aim of this research group is to explore metabolic aberrations in endocrine diseases for the identification and validation of new biomarkers. We use transcriptomic, proteomic and metabolomic approaches in close collaboration with the Dept of Endocrinology, OUS.

Research projects

Finding new biomarkers:

  • Diabetes:
    • Proteomic / metabolomic profiling ofhuman insulin producing cells aiming at discovering biomarkers for cell mas / function
    • Posttranslational modification of albumin in diabetes and late complications of diabetes
  • Thyroid disease:
    • Prospective evaluation of biomarkers of tear fluid in Graves ophtalmopathy
    • Metabolomic profiling of tear fluid in Graves ophtalmopathy

Basal studies:

  • Functional studies of genetic modifications in thyroid hormone resistance
  • Proteomic / metabolomic profiling of human fat tissue
  • Gene expression ofvitamin D stimulated insulin producing cells
  • Metabolomic profiling of hyperglycemic clamp in humans
  • Proteomic profiling of CSF in narcolepsy

Other projects:

  • Influence of estrogen supplementations on cortisol measurements in humans
  • Steroid profiling in congenital adrenal hyperplasia

Contact information

Group Leader Per Medbøe Thorsby, MD, PhD, Ass. Prof. (HIOA)
Hormone Laboratory, Department of Medical Biochemistry
Tel: + 47 23 03 30 43/ + 47 22 89 47 08