❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Tumor Biology ❭ Molecular Biology of Sarcomas [Wesche]

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Recent publications

Kostas M, Munthe E, Haugsten EM, Mateus D, Sørensen V, Laerdahl JK, Szybowska P, Wiedlocha A, Lecaudey LA, Nakken S, Schink KO, Stenmark H, Wesche J (2026)
Unconventional activation of the proto-oncogene FGFR1 by extracellular phosphate via H2O2-mediated kinase oxidation
Cell Rep, 45 (6), 117504 (in press)
DOI 10.1016/j.celrep.2026.117504, PubMed 42247296

Napolitano A, Joensuu H, Rothschild S, Evans D, Heinrich MC, Sutton TL, Mayo SC, Boye K, Falkenhorst J, Le Cesne A, Hohenberger P, Rutkowski P, van Houdt WJ, Steeghs N, Gelderblom H, Desar IME, Pantaleo MA, Nishida T, Reichardt P, Blay JY, Somaiah N, Haddad EFN, Grignani G, Baldi GG, Steigen SE et al. (2026)
Adjuvant Imatinib or Observation in Patients With Gastrointestinal Stromal Tumors With KIT Exon 9 Mutations
JAMA Oncol, 12 (4), 407-412
DOI 10.1001/jamaoncol.2026.0007, PubMed 41746633

Moura DS, Lopez-Marti J, Tawbi H, Keung E, Wani K, Lazar A, Wang WL, Ingram DR, Meza-Zepeda LA, Myklebost O, Burgess M, Mondaza-Hernandez JL, Hindi N, Martín-Broto J (2026)
Validation of a Seven-Gene Predictive SIGNature for the Efficacy of Immuno-Oncology PD-1 Inhibitors in Patients with Sarcoma
Clin Cancer Res, 32 (7), 1258-1265
DOI 10.1158/1078-0432.CCR-25-2580, PubMed 41537707



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