Publications 2025

Bugssa G, Teklehaymanot T, Medhin G, Nayagam S, Johannessen A, Berhe N (2025)
Prevalence and Factors Associated With Hepatitis B Virus Infection in Tigray Region, Northern Ethiopia
32 (10), e70077
DOI 10.1111/jvh.70077, PubMed 40952341

Desalegn H, Berhe N, Rossvoll L, Girma F, Brhane D, Hussen A, Cheneke W, Johannessen A (2025)
Time to Initiation of Hepatitis B Treatment is Reduced With the Use of the Xpert HBV Viral Load Kit
12 (5), ofaf238
DOI 10.1093/ofid/ofaf238, PubMed 40352629

Desalegn H, Rossvoll L, Hunduma F, Berhe N, Johannessen A (2025)
Hepatitis B treatment in Africa: learning points from a scale-up programme in Ethiopia
10 (3), 190-192
DOI 10.1016/S2468-1253(24)00396-0, PubMed 39954687

Farah AI, Abdi HM, Mohmed AJ, Abase SM, Ismail MM, Qalib JM, Johannessen A, Orlien SMS (2025)
Seroprevalence of transfusion transmitted infections among blood donors in Hargeisa, Somaliland: a retrospective study
25 (1), 2950
DOI 10.1186/s12889-025-24411-7, PubMed 40866847

Johannessen A (2025)
Early antiviral therapy in adults with moderate to highly viraemic chronic hepatitis B
10 (4), 276-277
DOI 10.1016/S2468-1253(25)00008-1, PubMed 39914433

Malme KB, Berhe N, Hunduma F, Desalegn H, Johannessen A (2025)
Decentralization of hepatitis B care in sub-Saharan Africa: study protocol for a prospective cohort assessing three models of care in rural Ethiopia
25 (1), 1223
DOI 10.1186/s12913-025-13340-1, PubMed 41029661

Rossvoll L, Desalegn H, Gudissa FG, Birhanu D, Hussen A, Cheneke W, Jeylan A, Debela EA, Yusuf M, Sugule A, Berhanu N, Gudina EK, Orlien SM, Stockdale AJ, Berhe N, Johannessen A (2025)
Treatment of chronic hepatitis B in Ethiopia: 1-year results from a real-life, multicentre, prospective cohort study
13 (11), e1914-e1923
DOI 10.1016/S2214-109X(25)00309-2, PubMed 41109262

Voeller AS, Johannessen A, Abebe ZZ, Adugna W, Gamkrelidze I, Seyoum E, Gebremedhin LT, Meselu MG, Nigussie SA, Silesh A, Razavi H, Razavi-Shearer D, Tirsite G, Desalegn H (2025)
The Disease and Economic Burden of HBV and HCV in Ethiopia
32 (2), e14053
DOI 10.1111/jvh.14053, PubMed 39815994

Publications 2024

Arefaine M, Johannessen A, Teklehaymanot T, Mihret A, Alemayehu DH, Osman M, Mulu A, Berhe N (2024)
A prospective, multicenter study of hepatitis B birth-dose vaccine with or without hepatitis B immunoglobulin in preventing mother-to-child transmission of hepatitis B virus in Ethiopia
42 (26), 126461
DOI 10.1016/j.vaccine.2024.126461, PubMed 39426287

Desalegn H, Yang X, Yen YS, Berhe N, Kenney B, Siwo GH, Tang W, Zhu J, Waljee AK, Johannessen A (2024)
Machine-learning methodologies to predict disease progression in chronic hepatitis B in Africa
8 (12)
DOI 10.1097/HC9.0000000000000584, PubMed 39774109

Ismael NY, Usmael SA, Belay NB, Mekonen HD, Johannessen A, Orlien SM (2024)
Chronic hepatitis B virus infection in Eastern Ethiopia: Clinical characteristics and determinants of cirrhosis
16 (7), 995-1008
DOI 10.4254/wjh.v16.i7.995, PubMed 39086536

Jemutai J, Downs L, Anderson M, Cohen C, Seeley J, Sultan B, Ko J, Flanagan S, Iwuji C, Halford R, Fernandes O, Vickerman P, Johannessen A, Matthews PC (2024)
Elimination of hepatitis B requires recognition of catastrophic costs for patients and their families
10 (2), 100-103
DOI 10.1016/S2468-1253(24)00384-4, PubMed 39681128

Johannessen A, Reikvam DH, Aleman S, Berhe N, Weis N, Desalegn H, Stenstad T, Heggelund L, Samuelsen E, Karlsen LN, Lindahl K, Pettersen FO, Iversen J, Kleppa E, Bollerup S, Winckelmann AA, Brugger-Synnes P, Simonsen HE, Svendsen J, Kran AB, Holmberg M, Olsen IC, Rueegg CS, Dalgard O (2024)
Clinical trial: An open-label, randomised trial of different re-start strategies after treatment withdrawal in HBeAg negative chronic hepatitis B
60 (4), 434-445
DOI 10.1111/apt.18147, PubMed 38970293

Johannessen A, Reikvam DH, Dalgard O (2024)
Letter: Should HBV Therapy Be Stopped Based on HBsAg Level Alone? Authors' Reply
61 (2), 404-405
DOI 10.1111/apt.18439, PubMed 39651841

Minier N, Guingané AN, Okeke E, Sinkala E, Johannessen A, Andersson MI, Davwar P, Desalegn H, Duguru M, Fall F, Mboup S, Maponga T, Matthews PC, Ramírez Mena A, Ndow G, Orlien SMS, Riches N, Seydi M, Sonderup M, Spearman CW, Stockdale AJ, Taljaard J, Vinikoor M, Wandeler G, Lemoine M et al. (2024)
Development and evaluation of a simple treatment eligibility score (HEPSANET) to decentralise hepatitis B care in Africa: a cross-sectional study
9 (4), 323-332
DOI 10.1016/S2468-1253(23)00449-1, PubMed 38367633

Publications 2023

Desalegn H, Orlien SMS, Aberra H, Mamo E, Grude S, Hommersand K, Berhe N, Gundersen SG, Johannessen A (2023)
Five-year results of a treatment program for chronic hepatitis B in Ethiopia
21 (1), 373
DOI 10.1186/s12916-023-03082-4, PubMed 37775742

Holmberg M, Aass HCD, Dalgard O, Samuelsen E, Sun D, Björkström NK, Johannessen A, Reikvam DH (2023)
Treatment cessation in HBeAg-negative chronic hepatitis B: clinical response is associated with increase in specific proinflammatory cytokines
13 (1), 22590
DOI 10.1038/s41598-023-50216-y, PubMed 38114718

Isa YS, Sicsic J, Njuguna H, Ward J, Chakroun M, El-Kassas M, Ramanampamonjy R, Chalal S, Vincent JP, Andersson M, Desalegn H, Fall F, Johannessen A, Matthews PC, Ndow G, Okeke E, Riches N, Seydi M, Sinkala E, Spearman CW, Stockdale A, Vinikoor MJ, Wandeler G, Sombié R, Lemoine M et al. (2023)
Informing a target product profile for rapid tests to identify HBV-infected pregnant women with high viral loads: a discrete choice experiment with African healthcare workers
21 (1), 243
DOI 10.1186/s12916-023-02939-y, PubMed 37403107

Johannessen A (2023)
Is it time for a paradigm shift in treatment guidelines for chronic hepatitis B?
8 (9), 784
DOI 10.1016/S2468-1253(23)00236-4, PubMed 37517416

Trøseid M, Arribas JR, Assoumou L, Holten AR, Poissy J, Terzić V, Mazzaferri F, Baño JR, Eustace J, Hites M, Joannidis M, Paiva JA, Reuter J, Püntmann I, Patrick-Brown TDJH, Westerheim E, Nezvalova-Henriksen K, Beniguel L, Dahl TB, Bouscambert M, Halanova M, Péterfi Z, Tsiodras S, Rezek M, Briel M et al. (2023)
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655

Woldemedihn GM, Aberra H, Desalegn H, Berhe N, Belay DB, Rueegg CS, Johannessen A (2023)
Renal Safety of Long-term Tenofovir Disoproxil Fumarate Treatment in Patients With Chronic Hepatitis B
10 (8), ofad404
DOI 10.1093/ofid/ofad404, PubMed 37614515

Publications 2022

Johannessen A, Gebremedhin LT, Desalegn H (2022)
New WHO hepatitis B treatment guidelines: look to Ethiopia
10 (12), e1711-e1712
DOI 10.1016/S2214-109X(22)00420-X, PubMed 36400081

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Publications 2021

Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903

Johannessen A, Mekasha B, Desalegn H, Aberra H, Stene-Johansen K, Berhe N (2021)
Mother-to-Child Transmission of Hepatitis B Virus in Ethiopia
9 (5)
DOI 10.3390/vaccines9050430, PubMed 33925930

Kåsine T, Dyrhol-Riise AM, Barratt-Due A, Kildal AB, Olsen IC, Nezvalova-Henriksen K, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Berg Å, Johannessen A, Heggelund L, Dahl TB, Halvorsen B, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR et al. (2021)
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368

Lerum TV, Maltzahn NN, Aukrust P, Trøseid M, Henriksen KN, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Haugli M, Blomberg B, Kittang BR, Johannessen A, Hannula R, Aballi S, Kildal AB, Eiken R, Dahl TB, Lund-Johansen F, Müller F, Rodriguez JR, Meltzer C, Einvik G, Ueland T, Olsen IC, NOR-SOLIDARITY Consortium et al. (2021)
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380

Publications 2020

Desalegn H, Chanie Y, Shume P, Delil M, Gupta N, Johannessen A (2020)
Assessment of Noninvasive Markers of Liver Fibrosis in Patients With Chronic Hepatitis C in Ethiopia
16 (4), 168-172
DOI 10.1002/cld.1040, PubMed 33163170

Orlien SMS, Ahmed TA, Ismael NY, Berhe Belay N, Kran AB, Gundersen SG, Johannessen A (2020)
Field performance of HBsAg rapid diagnostic tests in rural Ethiopia
289, 114061
DOI 10.1016/j.jviromet.2020.114061, PubMed 33388369

Woldemedihn GM, Rueegg CS, Desalegn H, Aberra H, Berhe N, Johannessen A (2020)
Validity of a point-of-care viral load test for hepatitis B in a low-income setting
289, 114057
DOI 10.1016/j.jviromet.2020.114057, PubMed 33359613

Publications 2019

Aberra H, Desalegn H, Berhe N, Mekasha B, Medhin G, Gundersen SG, Johannessen A (2019)
The WHO guidelines for chronic hepatitis B fail to detect half of the patients in need of treatment in Ethiopia
70 (6), 1065-1071
DOI 10.1016/j.jhep.2019.01.037, PubMed 30929749

Al-Shudifat AE, Azab M, Johannessen A, Agraib LM, Tayyem RF (2019)
Is the Intake of Antioxidants Associated With Risk of Coronary Artery Disease? A Jordanian Case-Control Study
Top. Clin. Nutr., 34 (4), 259-268
DOI 10.1097/TIN.0000000000000185

Desalegn H, Aberra H, Berhe N, Medhin G, Mekasha B, Gundersen SG, Johannessen A (2019)
Predictors of mortality in patients under treatment for chronic hepatitis B in Ethiopia: a prospective cohort study
19 (1), 74
DOI 10.1186/s12876-019-0993-1, PubMed 31092203

Johannessen A, Aberra H, Desalegn H, Gordien E, Berhe N (2019)
A novel score to select patients for treatment in chronic hepatitis B: Results from a large Ethiopian cohort
71 (4), 840-841
DOI 10.1016/j.jhep.2019.04.006, PubMed 31383377

Orlien SMS, Berhe NB, Morgan MY, Johannessen A (2019)
Khat-related liver disease in sub-Saharan Africa: neglected, yet important
7 (3), e310
DOI 10.1016/S2214-109X(18)30527-8, PubMed 30784630

Publications 2018

Al-Shudifat AE, Azab M, Johannessen A, Al-Shdaifat A, Agraib LM, Tayyem RF (2018)
Elevated fasting blood glucose, but not obesity, is associated with coronary artery disease in patients undergoing elective coronary angiography in a referral hospital in Jordan
Ann. Saudi Med., 38 (2), 111-117
DOI 10.5144/0256-4947.2018.111

Azab M, Al-Shudifat AE, Johannessen A, Al-Shdaifat A, Agraib LM, Tayyem RF (2018)
Are Risk Factors for Coronary Artery Disease Different in Persons With and Without Obesity?
16 (8), 440-445
DOI 10.1089/met.2017.0152, PubMed 30088947

Desalegn H, Aberra H, Berhe N, Mekasha B, Stene-Johansen K, Krarup H, Pereira AP, Gundersen SG, Johannessen A (2018)
Treatment of chronic hepatitis B in sub-Saharan Africa: 1-year results of a pilot program in Ethiopia
16 (1), 234
DOI 10.1186/s12916-018-1229-x, PubMed 30554571

Orlien SMS, Ahmed TA, Ismael NY, Berhe N, Lauritzen T, Gundersen SG, Johannessen A (2018)
High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor?
2018, 4980597
DOI 10.1155/2018/4980597, PubMed 30675469

Orlien SMS, Ismael NY, Ahmed TA, Berhe N, Lauritzen T, Roald B, Goldin RD, Stene-Johansen K, Dyrhol-Riise AM, Gundersen SG, Morgan MY, Johannessen A (2018)
Unexplained chronic liver disease in Ethiopia: a cross-sectional study
18 (1), 27
DOI 10.1186/s12876-018-0755-5, PubMed 29439653

Orlien SMS, Sandven I, Berhe NB, Ismael NY, Ahmed TA, Stene-Johansen K, Gundersen SG, Morgan MY, Johannessen A (2018)
Khat chewing increases the risk for developing chronic liver disease: A hospital-based case-control study
68 (1), 248-257
DOI 10.1002/hep.29809, PubMed 29369368

Publications 2017

Aberra H, Desalegn H, Berhe N, Medhin G, Stene-Johansen K, Gundersen SG, Johannessen A (2017)
Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa
17 (1), 438
DOI 10.1186/s12879-017-2549-8, PubMed 28629395

Aberra H, Gordien E, Desalegn H, Berhe N, Medhin G, Mekasha B, Gundersen SG, Gerber A, Stene-Johansen K, Øverbø J, Johannessen A (2017)
Hepatitis delta virus infection in a large cohort of chronic hepatitis B patients in Ethiopia
38 (6), 1000-1009
DOI 10.1111/liv.13607, PubMed 28980394

Al-Shudifat AE, Al-Shdaifat A, Al-Abdouh AA, Aburoman MI, Otoum SM, Sweedan AG, Khrais I, Abdel-Hafez IH, Johannessen A (2017)
Diabetes Risk Score in a Young Student Population in Jordan: A Cross-Sectional Study
J. Diabetes Res., 2017, 8290710
DOI 10.1155/2017/8290710

Al-Shudifat AE, Johannessen A, Azab M, Al-Shdaifat A, AbuMweis SS, Agraib LM, Tayyem RF (2017)
Risk factors for coronary artery disease in patients undergoing elective coronary angiography in Jordan
BMC Cardiovasc. Disord., 17, 183
DOI 10.1186/s12872-017-0620-4

Desalegn H, Aberra H, Berhe N, Gundersen SG, Johannessen A (2017)
Are non-invasive fibrosis markers for chronic hepatitis B reliable in sub-Saharan Africa?
37 (10), 1461-1467
DOI 10.1111/liv.13393, PubMed 28222249

Desalegn H, Johannessen A (2017)
Response to Non-invasive fibrosis markers for chronic hepatitis B in sub-Saharan Africa
Liver Int., 37 (11), 1739
DOI 10.1111/liv.13425

Publications 2016

Stene-Johansen K, Yaqoob N, Overbo J, Aberra H, Desalegn H, Berhe N, Johannessen A (2016)
Dry Blood Spots a Reliable Method for Measurement of Hepatitis B Viral Load in Resource-Limited Settings
11 (11), e0166201
DOI 10.1371/journal.pone.0166201, PubMed 27820845

Publications 2015

Johannessen A, Lemoine M (2015)
Is aspartate aminotransferase-to-platelet ratio index a reliable tool in human immunodeficiency virus patients in Africa?
35 (8), 2059
DOI 10.1111/liv.12793, PubMed 25646656

Publications 2014

Pettersen PS, Brox IK, Naman E, Bruun JN, Dyrhol-Riise AM, Trøseid M, Johannessen A (2014)
Antiretroviral treatment failure predicts mortality in rural Tanzania
26 (9), 633-9
DOI 10.1177/0956462414548460, PubMed 25122578

Shao ER, Kifaro EG, Chilumba IB, Nyombi BM, Moyo S, Gaseitsiwe S, Musonda R, Johannessen A, Kibiki G, Essex M (2014)
HIV-1 drug mutations in children from northern Tanzania
69 (7), 1928-32
DOI 10.1093/jac/dku087, PubMed 24729604

Publications 2012

Brantsæter AB, Johannessen A, Holberg-Petersen M, Sandvik L, Naman E, Kivuyo SL, Rollag H, Bruun JN, Kvale D (2012)
Cytomegalovirus viremia in dried blood spots is associated with an increased risk of death in HIV-infected patients: a cohort study from rural Tanzania
16 (12), e879-85
DOI 10.1016/j.ijid.2012.08.003, PubMed 23031419

Publications 2011

Johannessen A (2011)
Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital-author's response
J. Antimicrob. Chemother., 66 (4), 957-958
DOI 10.1093/jac/dkr042

Johannessen A (2011)
Are men the losers of the antiretroviral treatment scale-up?
Aids, 25 (9), 1225-1226
DOI 10.1097/QAD.0b013e32834403b8

Johannessen A (2011)
Antiretroviral treatment of HIV/AIDS in rural Tanzania: long-term outcome and simplified monitoring tools
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 1123, 1 b. (flere pag.)
BIBSYS 11289786x, ISBN 978-82-8264-128-9

Johannessen A, Naman E, Gundersen SG, Bruun JN (2011)
Antiretroviral treatment reverses HIV-associated anemia in rural Tanzania
11, 190
DOI 10.1186/1471-2334-11-190, PubMed 21745396

Publications 2010

Bratholm C, Johannessen A, Naman E, Gundersen SG, Kivuyo SL, Holberg-Petersen M, Ormaasen V, Bruun JN (2010)
Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital
65 (9), 1996-2000
DOI 10.1093/jac/dkq234, PubMed 20576637

Johannessen A (2010)
Dried blood spots in HIV monitoring: applications in resource-limited settings
2 (11), 1893-908
DOI 10.4155/bio.10.120, PubMed 21083497

Johannessen A (2010)
Quantification of HIV-1 RNA on dried blood spots
Aids, 24 (3), 475-476
DOI 10.1097/QAD.0b013e3283365383

Johannessen A, Garrido C, Zahonero N, Naman E, de Mendoza C (2010)
HIV-1 drug resistance testing from dried blood spots collected in rural Tanzania using the ViroSeq HIV-1 Genotyping System
66 (2), 260-4
DOI 10.1093/jac/dkq433, PubMed 21115444

Johannessen A, Holberg-Petersen M, Lövgaarden G, Naman E, Ormaasen V, Matee MI, Gundersen SG, Bruun JN (2010)
HIV type-1 drug resistance testing on dried blood spots is feasible and reliable in patients who fail antiretroviral therapy in rural Tanzania
15 (7), 1003-9
DOI 10.3851/IMP1660, PubMed 21041915

Trøseid M, Johannessen A (2010)
[The battle against HIV can be won, but there is not enough money!]
130 (16), 1599-600
DOI 10.4045/tidsskr.10.0705, PubMed 20805855

Trøseid M, Johannessen A (2010)
[A step in the right direction]
130 (22), 2223
DOI 10.4045/tidsskr.10.1100, PubMed 21109841

Publications 2009

Johannessen A, Garrido C, Zahonero N, Sandvik L, Naman E, Kivuyo SL, Kasubi MJ, Gundersen SG, Bruun JN, de Mendoza C (2009)
Dried blood spots perform well in viral load monitoring of patients who receive antiretroviral treatment in rural Tanzania
49 (6), 976-81
DOI 10.1086/605502, PubMed 19663598

Johannessen A, Naman E, Kivuyo SL, Kasubi MJ, Holberg-Petersen M, Matee MI, Gundersen SG, Bruun JN (2009)
Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania
9, 108
DOI 10.1186/1471-2334-9-108, PubMed 19583845

Johannessen A, Trøseid M, Calmy A (2009)
Dried blood spots can expand access to virological monitoring of HIV treatment in resource-limited settings
64 (6), 1126-9
DOI 10.1093/jac/dkp353, PubMed 19776036

Publications 2008

Johannessen A, Naman E, Ngowi BJ, Sandvik L, Matee MI, Aglen HE, Gundersen SG, Bruun JN (2008)
Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania
BMC Infect. Dis., 8, 52
DOI 10.1186/1471-2334-8-52