Publications

Publications by Maria Lyngaas Torgersen

51 publications found

Publications 2021

  1. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  2. Øverbye A, Torgersen ML, Sønstevold T, Iversen TG, Mørch Ý, Skotland T, Sandvig K (2021)
    Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: Toxicity and changes in the proteome of breast, colon and prostate cancer cells
    Nanotoxicology
    DOI 10.1080/17435390.2021.1924888, PubMed 34047629
  3. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035

Publications 2020

  1. Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
    The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
    Toxicology, 433-434, 152405
    DOI 10.1016/j.tox.2020.152405, PubMed 32044396
  2. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  3. Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
    Biological response and cytotoxicity induced by lipid nanocapsules
    J Nanobiotechnology, 18 (1), 5
    DOI 10.1186/s12951-019-0567-y, PubMed 31907052
  4. Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
    Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
    J Biomed Nanotechnol, 16 (4), 419-431
    DOI 10.1166/jbn.2020.2911, PubMed 32970975

Publications 2019

  1. Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
    The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
    J Biol Chem, 294 (20), 8197-8217
    DOI 10.1074/jbc.RA118.002829, PubMed 30926605
  2. Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
    Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
    Nanotoxicology, 13 (6), 761-782
    DOI 10.1080/17435390.2019.1576238, PubMed 30760074

Publications 2018

  1. SenGupta T, Torgersen ML, Kassahun H, Vellai T, Simonsen A, Nilsen H (2018)
    Publisher Correction: Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy
    Nat Commun, 9, 16206
    DOI 10.1038/ncomms16206, PubMed 29595188
  2. Zmajkovic J, Lundberg P, Nienhold R, Torgersen ML, Sundan A, Waage A, Skoda RC (2018)
    A Gain-of-Function Mutation in EPO in Familial Erythrocytosis
    N Engl J Med, 378 (10), 924-930
    DOI 10.1056/NEJMoa1709064, PubMed 29514032

Publications 2017

  1. Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
    PtdIns3P controls mTORC1 signaling through lysosomal positioning
    J Cell Biol, 216 (12), 4217-4233
    DOI 10.1083/jcb.201611073, PubMed 29030394
  2. Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
    Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
    PLoS One, 12 (1), e0170716
    DOI 10.1371/journal.pone.0170716, PubMed 28114329
  3. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

  1. Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
    PIKfyve inhibition increases exosome release and induces secretory autophagy
    Cell Mol Life Sci, 73 (24), 4717-4737
    DOI 10.1007/s00018-016-2309-8, PubMed 27438886
  2. Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
    Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
    Oncotarget, 7 (48), 79885-79900
    DOI 10.18632/oncotarget.13089, PubMed 27829218
  3. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM et al. (2016)
    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
    Autophagy, 12 (1), 1-222
    DOI 10.1080/15548627.2015.1100356, PubMed 26799652
  4. Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
    The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
    Oncotarget, 7 (52), 86871-86888
    DOI 10.18632/oncotarget.13508, PubMed 27894086

Publications 2015

  1. Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
    Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
    PLoS One, 10 (5), e0129214
    DOI 10.1371/journal.pone.0129214, PubMed 26017782
  2. Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK (2015)
    Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy
    Autophagy, 11 (3), 460-71
    DOI 10.1080/15548627.2015.1009797, PubMed 25749095
  3. Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
    Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
    Biochem J, 470 (1), 23-37
    DOI 10.1042/BJ20141562, PubMed 26251444
  4. Naderi EH, Skah S, Ugland H, Myklebost O, Sandnes DL, Torgersen ML, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2015)
    Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death
    Mol Cancer, 14, 14
    DOI 10.1186/s12943-014-0278-9, PubMed 25623255
  5. Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
    Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
    Molecules, 20 (7), 13313-23
    DOI 10.3390/molecules200713313, PubMed 26205056

Publications 2014

  1. Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
    LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
    Traffic, 15 (12), 1390-405
    DOI 10.1111/tra.12227, PubMed 25216107
  2. Solhaug A, Torgersen ML, Holme JA, Lagadic-Gossmann D, Eriksen GS (2014)
    Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol
    Toxicology, 326, 119-29
    DOI 10.1016/j.tox.2014.10.009, PubMed 25456271

Publications 2013

  1. Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG (2013)
    Modulation of intracellular calcium homeostasis blocks autophagosome formation
    Autophagy, 9 (10), 1475-90
    DOI 10.4161/auto.25900, PubMed 23970164
  2. Follin-Arbelet V, Torgersen ML, Naderi EH, Misund K, Sundan A, Blomhoff HK (2013)
    Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway
    Cancer Lett, 335 (2), 323-31
    DOI 10.1016/j.canlet.2013.02.042, PubMed 23454584
  3. SenGupta T, Torgersen ML, Kassahun H, Vellai T, Simonsen A, Nilsen H (2013)
    Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy
    Nat Commun, 4, 2674
    DOI 10.1038/ncomms3674, PubMed 24154628
  4. Torgersen ML, Engedal N, Bøe SO, Hokland P, Simonsen A (2013)
    Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells
    Blood, 122 (14), 2467-76
    DOI 10.1182/blood-2013-05-500629, PubMed 23970379
  5. Torgersen ML, Simonsen A (2013)
    Autophagy: friend or foe in the treatment of fusion protein-associated leukemias?
    Autophagy, 9 (12), 2175-7
    DOI 10.4161/auto.26559, PubMed 24145192

Publications 2011

  1. Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
    Shiga toxin and its use in targeted cancer therapy and imaging
    Microb Biotechnol, 4 (1), 32-46
    DOI 10.1111/j.1751-7915.2010.00180.x, PubMed 21255370

Publications 2010

  1. Pust S, Dyve AB, Torgersen ML, van Deurs B, Sandvig K (2010)
    Interplay between toxin transport and flotillin localization
    PLoS One, 5 (1), e8844
    DOI 10.1371/journal.pone.0008844, PubMed 20107503
  2. Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
    Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
    FEBS Lett, 584 (12), 2626-34
    DOI 10.1016/j.febslet.2010.04.008, PubMed 20385131
  3. Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
    The Intracellular Journey of Shiga Toxins
    The Open Toxinology Journal, 3, 3-12
    PublikaID 24
  4. Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
    Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
    FEMS Immunol Med Microbiol, 61 (1), 63-75
    DOI 10.1111/j.1574-695X.2010.00749.x, PubMed 21054580

Publications 2009

  1. Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
    Endocytosis and retrograde transport of Shiga toxin
    Toxicon, 56 (7), 1181-5
    DOI 10.1016/j.toxicon.2009.11.021, PubMed 19951719
  2. Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell Signal, 21 (7), 1161-8
    DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168

Publications 2008

  1. Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
    Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
    Histochem Cell Biol, 129 (3), 267-76
    DOI 10.1007/s00418-007-0376-5, PubMed 18193449

Publications 2007

  1. Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
    Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
    J Biol Chem, 282 (22), 16317-28
    DOI 10.1074/jbc.M610886200, PubMed 17403690
  2. Wälchli S, Skånland SS, Gregers TF, Lauvrak SU, Torgersen ML, Ying M, Kuroda S, Maturana A, Sandvig K (2007)
    The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking
    Mol Biol Cell, 19 (1), 95-104
    DOI 10.1091/mbc.e07-06-0565, PubMed 17959827

Publications 2005

  1. Hommelgaard AM, Roepstorff K, Vilhardt F, Torgersen ML, Sandvig K, van Deurs B (2005)
    Caveolae: stable membrane domains with a potential for internalization
    Traffic, 6 (9), 720-4
    DOI 10.1111/j.1600-0854.2005.00314.x, PubMed 16101676
  2. Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
    Shiga toxin regulates its entry in a Syk-dependent manner
    Mol Biol Cell, 17 (3), 1096-109
    DOI 10.1091/mbc.e05-08-0766, PubMed 16371508
  3. Torgersen ML, Lauvrak SU, Sandvig K (2005)
    The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
    FEBS J, 272 (16), 4103-13
    DOI 10.1111/j.1742-4658.2005.04835.x, PubMed 16098193

Publications 2004

  1. Lauvrak SU, Torgersen ML, Sandvig K (2004)
    Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
    J Cell Sci, 117 (Pt 11), 2321-31
    DOI 10.1242/jcs.01081, PubMed 15126632
  2. Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
    Pathways followed by protein toxins into cells
    Int J Med Microbiol, 293 (7-8), 483-90
    DOI 10.1078/1438-4221-00294, PubMed 15149022

Publications 2002

  1. Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
    Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
    J Biol Chem, 278 (3), 1991-7
    DOI 10.1074/jbc.M209982200, PubMed 12419802

Publications 2001

  1. Sandvig K, Grimmer S, Lauvrak SU, Torgersen ML, Skretting G, van Deurs B, Iversen TG (2001)
    Pathways followed by ricin and Shiga toxin into cells
    Histochem Cell Biol, 117 (2), 131-41
    DOI 10.1007/s00418-001-0346-2, PubMed 11935289
  2. Torgersen ML, Skretting G, van Deurs B, Sandvig K (2001)
    Internalization of cholera toxin by different endocytic mechanisms
    J Cell Sci, 114 (Pt 20), 3737-47
    PubMed 11707525

Publications 2000

  1. Sandvig K, Grimmer S, Iversen TG, Rodal K, Torgersen ML, Nicoziani P, van Deurs B (2000)
    Ricin transport into cells: studies of endocytosis and intracellular transport
    Int J Med Microbiol, 290 (4-5), 415-20
    DOI 10.1016/S1438-4221(00)80055-7, PubMed 11111920

Publications 1999

  1. Hjertner O, Torgersen ML, Seidel C, Hjorth-Hansen H, Waage A, Børset M, Sundan A (1999)
    Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease
    Blood, 94 (11), 3883-8
    PubMed 10572104
  2. Skretting G, Torgersen ML, van Deurs B, Sandvig K (1999)
    Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
    J Cell Sci, 112 ( Pt 22), 3899-909
    PubMed 10547351

 

 
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