Kirsten Jane Skarstad

  • Group leader; Dr. philos.
  • +47 230 13 910

Mini CV

  • Graduate engineer from the Norwegian Institute of Technology 1981;
  • Dr. philos from the University of Oslo, 1987,
  • Postdoctoral fellow in professor Arthur Kornberg´s laboratory, Stanford University Medical School, 1988-1991;
  • Group leader, Department of Biophysics, Institute for Cancer Research, Norwegian Radium Hospital, 1991-1996;
  • Group leader, the Department of Cell Biology, Institute for Cancer Research, Norwegian Radium Hospital, 1996-present;
  • Adjunct professor at the Institute of Pharmacy, University of Oslo, 2000-present.
  • Member of the Board of the Science and Technology Division, The Norwegian Research Council, 2001-2003.
  • Member of the Evaluation Committee for the Norwegian Science and Technology Centers of Excellence, 2001-2002.
  • Member of the EU project QLK2-CT-2000-00634, 2000-2004
  • Member of FUGE platform CAMST (Advanced Microbial Science and Technology) 2003-2008
  • Member of  European Molecular Biology Organization (EMBO), 2004
  • Member of the Norwegian Academy of Science and Letters (Det Norske Vitenskaps-Akademi), 2008
  • Member of the EMBO Fellowship Committee, 2009-2012



Publications 2023

Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
A DnaA-dependent riboswitch for transcription attenuation of the his operon
mLife, 2 (2), 126-140
DOI 10.1002/mlf2.12075, PubMed 38817620

Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
A DnaA‐dependent riboswitch for transcription attenuation of the his operon
mLife, 2 (2), 126-140
DOI 10.1002/mlf2.12075, PublikaID 479

Publications 2021

Helgesen E, Sætre F, Skarstad K (2021)
Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli
Sci Rep, 11 (1), 474
DOI 10.1038/s41598-020-80043-4, PubMed 33436807

Lobie TA, Roba AA, Booth JA, Kristiansen KI, Aseffa A, Skarstad K, Bjørås M (2021)
Antimicrobial resistance: A challenge awaiting the post-COVID-19 era
Int J Infect Dis, 111, 322-325
DOI 10.1016/j.ijid.2021.09.003, PubMed 34508864

Publications 2020

Booth JA, Špírek M, Lobie TA, Skarstad K, Krejci L, Bjørås M (2020)
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
Sci Rep, 10 (1), 19422
DOI 10.1038/s41598-020-76426-2, PubMed 33173044

Nedal A, Ræder SB, Dalhus B, Helgesen E, Forstrøm RJ, Lindland K, Sumabe BK, Martinsen JH, Kragelund BB, Skarstad K, Bjørås M, Otterlei M (2020)
Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis
Nucleic Acids Res, 48 (10), 5540-5554
DOI 10.1093/nar/gkaa278, PubMed 32347931

Publications 2018

Nouri H, Monnier AF, Fossum-Raunehaug S, Maciag-Dorszynska M, Cabin-Flaman A, Képès F, Wegrzyn G, Szalewska-Palasz A, Norris V, Skarstad K, Janniere L (2018)
Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
DNA Res, 25 (6), 641-653
DOI 10.1093/dnares/dsy031, PubMed 30256918

Publications 2017

Flåtten I, Helgesen E, Pedersen IB, Waldminghaus T, Rothe C, Taipale R, Johnsen L, Skarstad K (2017)
Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
J Bacteriol, 199 (24)
DOI 10.1128/JB.00412-17, PubMed 28947673

Pedersen IB, Helgesen E, Flåtten I, Fossum-Raunehaug S, Skarstad K (2017)
SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
Nucleic Acids Res, 45 (11), 6471-6485
DOI 10.1093/nar/gkx263, PubMed 28407100

Publications 2016

Helgesen E, Fossum-Raunehaug S, Skarstad K (2016)
Lack of the H-NS Protein Results in Extended and Aberrantly Positioned DNA during Chromosome Replication and Segregation in Escherichia coli
J Bacteriol, 198 (8), 1305-16
DOI 10.1128/JB.00919-15, PubMed 26858102

Publications 2015

Flåtten I, Fossum-Raunehaug S, Taipale R, Martinsen S, Skarstad K (2015)
The DnaA Protein Is Not the Limiting Factor for Initiation of Replication in Escherichia coli
PLoS Genet, 11 (6), e1005276
DOI 10.1371/journal.pgen.1005276, PubMed 26047361

Helgesen E, Fossum-Raunehaug S, Sætre F, Schink KO, Skarstad K (2015)
Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
Nucleic Acids Res, 43 (5), 2730-43
DOI 10.1093/nar/gkv146, PubMed 25722374

Publications 2014

Fossum-Raunehaug S, Helgesen E, Stokke C, Skarstad K (2014)
Escherichia coli SeqA structures relocalize abruptly upon termination of origin sequestration during multifork DNA replication
PLoS One, 9 (10), e110575
DOI 10.1371/journal.pone.0110575, PubMed 25333813

Morigen M, Flåtten I, Skarstad K (2014)
The Escherichia coli datA site promotes proper regulation of cell division
Microbiology (Reading), 160 (Pt 4), 703-710
DOI 10.1099/mic.0.074898-0, PubMed 24574433

Odsbu I, Skarstad K (2014)
DNA compaction in the early part of the SOS response is dependent on RecN and RecA
Microbiology (Reading), 160 (Pt 5), 872-882
DOI 10.1099/mic.0.075051-0, PubMed 24615185

Publications 2013

Flåtten I, Skarstad K (2013)
The Fis protein has a stimulating role in initiation of replication in Escherichia coli in vivo
PLoS One, 8 (12), e83562
DOI 10.1371/journal.pone.0083562, PubMed 24358293

Skarstad K, Katayama T (2013)
Regulating DNA replication in bacteria
Cold Spring Harb Perspect Biol, 5 (4), a012922
DOI 10.1101/cshperspect.a012922, PubMed 23471435

Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
Single transmembrane peptide DinQ modulates membrane-dependent activities
PLoS Genet, 9 (2), e1003260
DOI 10.1371/journal.pgen.1003260, PubMed 23408903

Publications 2012

Fingland N, Flåtten I, Downey CD, Fossum-Raunehaug S, Skarstad K, Crooke E (2012)
Depletion of acidic phospholipids influences chromosomal replication in Escherichia coli
Microbiologyopen, 1 (4), 450-66
DOI 10.1002/mbo3.46, PubMed 23233230

Stokke C, Flåtten I, Skarstad K (2012)
An easy-to-use simulation program demonstrates variations in bacterial cell cycle parameters depending on medium and temperature
PLoS One, 7 (2), e30981
DOI 10.1371/journal.pone.0030981, PubMed 22348034

Waldminghaus T, Weigel C, Skarstad K (2012)
Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome
Nucleic Acids Res, 40 (12), 5465-76
DOI 10.1093/nar/gks187, PubMed 22373925

Publications 2011

Johnsen E, Wilson SR, Odsbu I, Krapp A, Malerod H, Skarstad K, Lundanes E (2011)
Hydrophilic interaction chromatography of nucleoside triphosphates with temperature as a separation parameter
J Chromatogr A, 1218 (35), 5981-6
DOI 10.1016/j.chroma.2011.01.066, PubMed 21315360

Publications 2010

Johnsen L, Flåtten I, Morigen, Dalhus B, Bjørås M, Waldminghaus T, Skarstad K (2010)
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
Mol Microbiol, 79 (2), 433-46
DOI 10.1111/j.1365-2958.2010.07453.x, PubMed 21219462

Johnsen L, Weigel C, von Kries J, Møller M, Skarstad K (2010)
A novel DNA gyrase inhibitor rescues Escherichia coli dnaAcos mutant cells from lethal hyperinitiation
J Antimicrob Chemother, 65 (5), 924-30
DOI 10.1093/jac/dkq071, PubMed 20228083

Stokke C, Waldminghaus T, Skarstad K (2010)
Replication patterns and organization of replication forks in Vibrio cholerae
Microbiology (Reading), 157 (Pt 3), 695-708
DOI 10.1099/mic.0.045112-0, PubMed 21163839

Waldminghaus T, Skarstad K (2010)
ChIP on Chip: surprising results are often artifacts
BMC Genomics, 11, 414
DOI 10.1186/1471-2164-11-414, PubMed 20602746

Publications 2009

Boeneman K, Fossum S, Yang Y, Fingland N, Skarstad K, Crooke E (2009)
Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments
Mol Microbiol, 72 (3), 645-57
DOI 10.1111/j.1365-2958.2009.06674.x, PubMed 19400775

Morigen, Odsbu I, Skarstad K (2009)
Growth rate dependent numbers of SeqA structures organize the multiple replication forks in rapidly growing Escherichia coli
Genes Cells, 14 (5), 643-57
DOI 10.1111/j.1365-2443.2009.01298.x, PubMed 19371375

Odsbu I, Morigen, Skarstad K (2009)
A reduction in ribonucleotide reductase activity slows down the chromosome replication fork but does not change its localization
PLoS One, 4 (10), e7617
DOI 10.1371/journal.pone.0007617, PubMed 19898675

Waldminghaus T, Skarstad K (2009)
The Escherichia coli SeqA protein
Plasmid, 61 (3), 141-50
DOI 10.1016/j.plasmid.2009.02.004, PubMed 19254745

Publications 2008

Bach T, Morigen, Skarstad K (2008)
The initiator protein DnaA contributes to keeping new origins inactivated by promoting the presence of hemimethylated DNA
J Mol Biol, 384 (5), 1076-85
DOI 10.1016/j.jmb.2008.09.042, PubMed 18835566

Flåtten I, Morigen, Skarstad K (2008)
DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin
Mol Microbiol, 71 (4), 1018-30
DOI 10.1111/j.1365-2958.2008.06585.x, PubMed 19170875

Fossum S, De Pascale G, Weigel C, Messer W, Donadio S, Skarstad K (2008)
A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication
FEMS Microbiol Lett, 281 (2), 210-4
DOI 10.1111/j.1574-6968.2008.01103.x, PubMed 18312360

Publications 2007

Fossum S, Crooke E, Skarstad K (2007)
Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli
EMBO J, 26 (21), 4514-22
DOI 10.1038/sj.emboj.7601871, PubMed 17914458

Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K (2007)
Functional taxonomy of bacterial hyperstructures
Microbiol Mol Biol Rev, 71 (1), 230-53
DOI 10.1128/MMBR.00035-06, PubMed 17347523

Norris V, den Blaauwen T, Doi RH, Harshey RM, Janniere L, Jiménez-Sánchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Misevic G, Ripoll C, Saier M, Skarstad K, Thellier M (2007)
Toward a hyperstructure taxonomy
Annu Rev Microbiol, 61, 309-29
DOI 10.1146/annurev.micro.61.081606.103348, PubMed 17896876

Publications 2006

Gon S, Camara JE, Klungsøyr HK, Crooke E, Skarstad K, Beckwith J (2006)
A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli
EMBO J, 25 (5), 1137-47
DOI 10.1038/sj.emboj.7600990, PubMed 16482221

Publications 2005

Bach T, Skarstad K (2005)
An oriC-like distribution of GATC sites mediates full sequestration of non-origin sequences in Escherichia coli
J Mol Biol, 350 (1), 7-11
DOI 10.1016/j.jmb.2005.04.055, PubMed 15922360

Morigen, Molina F, Skarstad K (2005)
Deletion of the datA site does not affect once-per-cell-cycle timing but induces rifampin-resistant replication
J Bacteriol, 187 (12), 3913-20
DOI 10.1128/JB.187.12.3913-3920.2005, PubMed 15939703

Odsbu I, Klungsøyr HK, Fossum S, Skarstad K (2005)
Specific N-terminal interactions of the Escherichia coli SeqA protein are required to form multimers that restrain negative supercoils and form foci
Genes Cells, 10 (11), 1039-49
DOI 10.1111/j.1365-2443.2005.00898.x, PubMed 16236133

Publications 2004

Bach T, Skarstad K (2004)
Re-replication from non-sequesterable origins generates three-nucleoid cells which divide asymmetrically
Mol Microbiol, 51 (6), 1589-600
DOI 10.1111/j.1365-2958.2003.03943.x, PubMed 15009887

Klungsøyr HK, Skarstad K (2004)
Positive supercoiling is generated in the presence of Escherichia coli SeqA protein
Mol Microbiol, 54 (1), 123-31
DOI 10.1111/j.1365-2958.2004.04239.x, PubMed 15458410

Molina F, Skarstad K (2004)
Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism
Mol Microbiol, 52 (6), 1597-612
DOI 10.1111/j.1365-2958.2004.04097.x, PubMed 15186411

Publications 2003

Bach T, Krekling MA, Skarstad K (2003)
Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division
EMBO J, 22 (2), 315-23
DOI 10.1093/emboj/cdg020, PubMed 12514137

Camara JE, Skarstad K, Crooke E (2003)
Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein
J Bacteriol, 185 (10), 3244-8
DOI 10.1128/JB.185.10.3244-3248.2003, PubMed 12730188

Fossum S, Søreide S, Skarstad K (2003)
Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2
Mol Microbiol, 47 (3), 619-32
DOI 10.1046/j.1365-2958.2003.t01-1-03329.x, PubMed 12535065

Kang S, Han JS, Park JH, Skarstad K, Hwang DS (2003)
SeqA protein stimulates the relaxing and decatenating activities of topoisomerase IV
J Biol Chem, 278 (49), 48779-85
DOI 10.1074/jbc.M308843200, PubMed 14512422

Miller C, Ingmer H, Thomsen LE, Skarstad K, Cohen SN (2003)
DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response
J Bacteriol, 185 (20), 6025-31
DOI 10.1128/JB.185.20.6025-6031.2003, PubMed 14526013

Morigen, Løbner-Olesen A, Skarstad K (2003)
Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks, delayed replication initiation and delayed cell division
Mol Microbiol, 50 (1), 349-62
DOI 10.1046/j.1365-2958.2003.03695.x, PubMed 14507385

Skarstad K, Boye E, Fanning E (2003)
Circles in the sand
EMBO Rep, 4 (7), 661-5
DOI 10.1038/sj.embor.embor888, PubMed 12835752

Skarstad K, Løbner-Olesen A (2003)
Stable co-existence of separate replicons in Escherichia coli is dependent on once-per-cell-cycle initiation
EMBO J, 22 (1), 140-50
DOI 10.1093/emboj/cdg003, PubMed 12505992

Slominska M, Wahl A, Wegrzyn G, Skarstad K (2003)
Degradation of mutant initiator protein DnaA204 by proteases ClpP, ClpQ and Lon is prevented when DNA is SeqA-free
Biochem J, 370 (Pt 3), 867-71
DOI 10.1042/BJ20021161, PubMed 12479794

Publications 2001

Morigen, Boye E, Skarstad K, Løbner-Olesen A (2001)
Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the datA region
Biochim Biophys Acta, 1521 (1-3), 73-80
DOI 10.1016/s0167-4781(01)00292-5, PubMed 11690638

Skarstad K, Torheim N, Wold S, Lurz R, Messer W, Fossum S, Bach T (2001)
The Escherichia coli SeqA protein binds specifically to two sites in fully and hemimethylated oriC and has the capacity to inhibit DNA replication and affect chromosome topology
Biochimie, 83 (1), 49-51
DOI 10.1016/s0300-9084(00)01207-4, PubMed 11254974

Slomińska M, Wegrzyn A, Konopa G, Skarstad K, Wegrzyn G (2001)
SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
Mol Microbiol, 40 (6), 1371-9
DOI 10.1046/j.1365-2958.2001.02480.x, PubMed 11442835

Zheng W, Li Z, Skarstad K, Crooke E (2001)
Mutations in DnaA protein suppress the growth arrest of acidic phospholipid-deficient Escherichia coli cells
EMBO J, 20 (5), 1164-72
DOI 10.1093/emboj/20.5.1164, PubMed 11230139

Publications 2000

Bernander R, Skarstad K (2000)
Mapping of a chromosome replication origin in an archaeon
Trends Microbiol, 8 (12), 535-7
DOI 10.1016/s0966-842x(00)01878-3, PubMed 11115744

Boye E, Løbner-Olesen A, Skarstad K (2000)
Limiting DNA replication to once and only once
EMBO Rep, 1 (6), 479-83
DOI 10.1093/embo-reports/kvd116, PubMed 11263490

Skarstad K, Lueder G, Lurz R, Speck C, Messer W (2000)
The Escherichia coli SeqA protein binds specifically and co-operatively to two sites in hemimethylated and fully methylated oriC
Mol Microbiol, 36 (6), 1319-26
DOI 10.1046/j.1365-2958.2000.01943.x, PubMed 10931282

Torheim NK, Boye E, Løbner-Olesen A, Stokke T, Skarstad K (2000)
The Escherichia coli SeqA protein destabilizes mutant DnaA204 protein
Mol Microbiol, 37 (3), 629-38
DOI 10.1046/j.1365-2958.2000.02031.x, PubMed 10931356

Publications 1999

Torheim NK, Skarstad K (1999)
Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC
EMBO J, 18 (17), 4882-8
DOI 10.1093/emboj/18.17.4882, PubMed 10469666

Publications 1998

Wold S, Boye E, Slater S, Kleckner N, Skarstad K (1998)
Effects of purified SeqA protein on oriC-dependent DNA replication in vitro
EMBO J, 17 (14), 4158-65
DOI 10.1093/emboj/17.14.4158, PubMed 9670030

Publications 1997

Stokke T, Smedshammer L, Jonassen TS, Blomhoff HK, Skarstad K, Steen HB (1997)
Uncoupling of the order of the S and M phases: effects of staurosporine on human cell cycle kinases
Cell Prolif, 30 (5), 197-218
DOI 10.1046/j.1365-2184.1997.00087.x, PubMed 9420612

Publications 1996

Boye E, Stokke T, Kleckner N, Skarstad K (1996)
Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins
Proc Natl Acad Sci U S A, 93 (22), 12206-11
DOI 10.1073/pnas.93.22.12206, PubMed 8901558

Jair KW, Yu X, Skarstad K, Thöny B, Fujita N, Ishihama A, Wolf RE (1996)
Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication
J Bacteriol, 178 (9), 2507-13
DOI 10.1128/jb.178.9.2507-2513.1996, PubMed 8626315

Wold S, Crooke E, Skarstad K (1996)
The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro
Nucleic Acids Res, 24 (18), 3527-32
DOI 10.1093/nar/24.18.3527, PubMed 8836178

Publications 1995

Skarstad K, Bernander R, Boye E (1995)
Analysis of DNA replication in vivo by flow cytometry
Methods Enzymol, 262, 604-13
DOI 10.1016/0076-6879(95)62047-8, PubMed 8594381

Skarstad K, Wold S (1995)
The speed of the Escherichia coli fork in vivo depends on the DnaB:DnaC ratio
Mol Microbiol, 17 (5), 825-31
DOI 10.1111/j.1365-2958.1995.mmi_17050825.x, PubMed 8596432

Slater S, Wold S, Lu M, Boye E, Skarstad K, Kleckner N (1995)
E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration
Cell, 82 (6), 927-36
DOI 10.1016/0092-8674(95)90272-4, PubMed 7553853

Publications 1994

Skarstad K, Boye E (1994)
The initiator protein DnaA: evolution, properties and function
Biochim Biophys Acta, 1217 (2), 111-30
DOI 10.1016/0167-4781(94)90025-6, PubMed 8110826

Steen HB, Jernaes MW, Skarstad K, Boye E (1994)
Staining and measurement of DNA in bacteria
Methods Cell Biol, 42 Pt B, 477-87
DOI 10.1016/s0091-679x(08)61091-2, PubMed 7533253

Wold S, Skarstad K, Steen HB, Stokke T, Boye E (1994)
The initiation mass for DNA replication in Escherichia coli K-12 is dependent on growth rate
EMBO J, 13 (9), 2097-102
DOI 10.1002/j.1460-2075.1994.tb06485.x, PubMed 8187762

Publications 1993

Skarstad K, Boye E (1993)
Degradation of individual chromosomes in recA mutants of Escherichia coli
J Bacteriol, 175 (17), 5505-9
DOI 10.1128/jb.175.17.5505-5509.1993, PubMed 8366035

Skarstad K, Thöny B, Hwang DS, Kornberg A (1993)
A novel binding protein of the origin of the Escherichia coli chromosome
J Biol Chem, 268 (8), 5365-70
PubMed 8449900

Publications 1991

Crooke E, Hwang DS, Skarstad K, Thöny B, Kornberg A (1991)
E. coli minichromosome replication: regulation of initiation at oriC
Res Microbiol, 142 (2-3), 127-30
DOI 10.1016/0923-2508(91)90019-7, PubMed 1925009

Publications 1990

Skarstad K, Baker TA, Kornberg A (1990)
Strand separation required for initiation of replication at the chromosomal origin of E.coli is facilitated by a distant RNA--DNA hybrid
EMBO J, 9 (7), 2341-8
DOI 10.1002/j.1460-2075.1990.tb07406.x, PubMed 1694129

Steen HB, Skarstad K, Boye E (1990)
DNA measurements of bacteria
Methods Cell Biol, 33, 519-26
DOI 10.1016/s0091-679x(08)60551-8, PubMed 2084483

Publications 1989

Løbner-Olesen A, Skarstad K, Hansen FG, von Meyenburg K, Boye E (1989)
The DnaA protein determines the initiation mass of Escherichia coli K-12
Cell, 57 (5), 881-9
DOI 10.1016/0092-8674(89)90802-7, PubMed 2541928

Skarstad K, Løbner-Olesen A, Atlung T, von Meyenburg K, Boye E (1989)
Initiation of DNA replication in Escherichia coli after overproduction of the DnaA protein
Mol Gen Genet, 218 (1), 50-6
DOI 10.1007/BF00330564, PubMed 2550764

Publications 1988

Boye E, Løbner-Olesen A, Skarstad K (1988)
Timing of chromosomal replication in Escherichia coli
Biochim Biophys Acta, 951 (2-3), 359-64
DOI 10.1016/0167-4781(88)90107-8, PubMed 2850013

Skarstad K, Boye E (1988)
Perturbed chromosomal replication in recA mutants of Escherichia coli
J Bacteriol, 170 (6), 2549-54
DOI 10.1128/jb.170.6.2549-2554.1988, PubMed 3286612

Skarstad K, von Meyenburg K, Hansen FG, Boye E (1988)
Coordination of chromosome replication initiation in Escherichia coli: effects of different dnaA alleles
J Bacteriol, 170 (2), 852-8
DOI 10.1128/jb.170.2.852-858.1988, PubMed 2828328

Publications 1987

Skarstad K (1987)
Chromosomal DNA replication in Escherichia coli studied by flow cytometry
Department of Biophysics, Institute for Cancer Research, The Norwegian Radium Hospital and The Norwegian Cancer Society, Oslo, 1 b. (flere pag.)
BIBSYS 872208214, ISBN 82-90187-38-6

von Meyenburg K, Boye E, Skarstad K, Koppes L, Kogoma T (1987)
Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12
J Bacteriol, 169 (6), 2650-8
DOI 10.1128/jb.169.6.2650-2658.1987, PubMed 3034862

Publications 1986

Skarstad K, Boye E, Steen HB (1986)
Timing of initiation of chromosome replication in individual Escherichia coli cells
EMBO J, 5 (7), 1711-7
DOI 10.1002/j.1460-2075.1986.tb04415.x, PubMed 3527695

Steen HB, Skarstad K, Boye E (1986)
Flow cytometry of bacteria: cell cycle kinetics and effects of antibiotics
Ann N Y Acad Sci, 468, 329-38
DOI 10.1111/j.1749-6632.1986.tb42050.x, PubMed 2942091

Publications 1985

Kogoma T, Skarstad K, Boye E, von Meyenburg K, Steen HB (1985)
RecA protein acts at the initiation of stable DNA replication in rnh mutants of Escherichia coli K-12
J Bacteriol, 163 (2), 439-44
DOI 10.1128/jb.163.2.439-444.1985, PubMed 2991187

Skarstad K, Steen HB, Boye E (1985)
Escherichia coli DNA distributions measured by flow cytometry and compared with theoretical computer simulations
J Bacteriol, 163 (2), 661-8
DOI 10.1128/jb.163.2.661-668.1985, PubMed 3894332

Publications 1984

Boye E, Köhnlein W, Skarstad K (1984)
Characterization of intracellular DNA strand breaks induced by neocarzinostatin in Escherichia coli cells
Nucleic Acids Res, 12 (21), 8281-91
DOI 10.1093/nar/12.21.8281, PubMed 6239141

Publications 1983

Boye E, Steen HB, Skarstad K (1983)
Flow cytometry of bacteria: a promising tool in experimental and clinical microbiology
J Gen Microbiol, 129 (4), 973-80
DOI 10.1099/00221287-129-4-973, PubMed 6350534

Skarstad K, Steen HB, Boye E (1983)
Cell cycle parameters of slowly growing Escherichia coli B/r studied by flow cytometry
J Bacteriol, 154 (2), 656-62
DOI 10.1128/jb.154.2.656-662.1983, PubMed 6341358

Publications 1982

Steen HB, Boye E, Skarstad K, Bloom B, Godal T, Mustafa S (1982)
Applications of flow cytometry on bacteria: cell cycle kinetics, drug effects, and quantitation of antibody binding
Cytometry, 2 (4), 249-57
DOI 10.1002/cyto.990020409, PubMed 7035105

Publications 1981

Boye E, Alver S, Skarstad K (1981)
Deoxyribonucleic acid replication in permeable and fully viable Escherichia coli cells
J Bacteriol, 145 (3), 1413-6
DOI 10.1128/jb.145.3.1413-1416.1981, PubMed 7009586

Skarstad KJ (1981)
DNA replication i Escherichia coli studert med to forskjellige metoder
Almenavdelingen, NTH, Trondheim, 77 bl
BIBSYS 061950661

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