PubMed registered articles Intracellular Transport group

Publications published since 1976 from OUS - Intracellular transport (Sandvig)

234 publications found

Publications 2020

  1. Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
    Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
    Cell Mol Life Sci
    DOI 10.1007/s00018-020-03551-6, PubMed 32447426
  2. Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
    Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
    J Mater Chem B (in press)
    DOI 10.1039/d0tb00861c, PubMed 32627783
  3. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
  4. Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
    Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
    Cells, 9 (5)
    DOI 10.3390/cells9051171, PubMed 32397238
  5. Skotland T, Kavaliauskiene S, Sandvig K (2020)
    The role of lipid species in membranes and cancer-related changes
    Cancer Metastasis Rev, 39 (2), 343-360
    DOI 10.1007/s10555-020-09872-z, PubMed 32314087
  6. Skotland T, Sagini K, Sandvig K, Llorente A (2020)
    An emerging focus on lipids in extracellular vesicles
    Adv Drug Deliv Rev (in press)
    DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
  7. Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
    The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
    Toxicology, 433-434, 152405
    DOI 10.1016/j.tox.2020.152405, PubMed 32044396
  8. Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
    Biological response and cytotoxicity induced by lipid nanocapsules
    J Nanobiotechnology, 18 (1), 5
    DOI 10.1186/s12951-019-0567-y, PubMed 31907052
  9. Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
    Analytical techniques for multiplex analysis of protein biomarkers
    Expert Rev Proteomics, 17 (4), 257-273
    DOI 10.1080/14789450.2020.1763174, PubMed 32427033

Publications 2019

  1. Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
    The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
    J Biol Chem, 294 (20), 8197-8217
    DOI 10.1074/jbc.RA118.002829, PubMed 30926605
  2. Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC (2019)
    The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses
    J Pharmacol Exp Ther, 370 (3), 581-592
    DOI 10.1124/jpet.119.258012, PubMed 30940695
  3. Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
    Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
    Int J Nanomedicine, 14, 6269-6285
    DOI 10.2147/IJN.S208938, PubMed 31496685
  4. Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    J Extracell Vesicles, 8 (1), 1684862
    DOI 10.1080/20013078.2019.1684862, PubMed 31762963
  5. Skotland T, Sandvig K (2019)
    The role of PS 18:0/18:1 in membrane function
    Nat Commun, 10 (1), 2752
    DOI 10.1038/s41467-019-10711-1, PubMed 31227693
  6. Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M (2019)
    Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
    Toxins (Basel), 11 (6)
    DOI 10.3390/toxins11060350, PubMed 31216687
  7. Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
    Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
    Nanotoxicology, 13 (6), 761-782
    DOI 10.1080/17435390.2019.1576238, PubMed 30760074

Publications 2018

  1. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
    Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
    J Control Release, 293, 183-192
    DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
  2. Popēna I, Ābols A, Saulīte L, Pleiko K, Zandberga E, Jēkabsons K, Endzeliņš E, Llorente A, Linē A, Riekstiņa U (2018)
    Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
    Cell Commun Signal, 16 (1), 17
    DOI 10.1186/s12964-018-0229-y, PubMed 29690889
  3. Sandvig K, Kavaliauskiene S, Skotland T (2018)
    Clathrin-independent endocytosis: an increasing degree of complexity
    Histochem Cell Biol, 150 (2), 107-118
    DOI 10.1007/s00418-018-1678-5, PubMed 29774430
  4. Skotland T, Hessvik NP, Sandvig K, Llorente A (2018)
    Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
    J Lipid Res, 60 (1), 9-18
    DOI 10.1194/jlr.R084343, PubMed 30076207
  5. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E et al. (2018)
    Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
    J Extracell Vesicles, 7 (1), 1535750
    DOI 10.1080/20013078.2018.1535750, PubMed 30637094

Publications 2017

  1. Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
    Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
    Traffic, 18 (3), 176-191
    DOI 10.1111/tra.12468, PubMed 28067430
  2. Boye E, Skotland T, Østerud B, Nissen-Meyer J (2017)
    Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
    EMBO Rep, 18 (3), 351-354
    DOI 10.15252/embr.201643540, PubMed 28167676
  3. Cambier S, Røgeberg M, Georgantzopoulou A, Serchi T, Karlsson C, Verhaegen S, Iversen TG, Guignard C, Kruszewski M, Hoffmann L, Audinot JN, Ropstad E, Gutleb AC (2017)
    Fate and effects of silver nanoparticles on early life-stage development of zebrafish (Danio rerio) in comparison to silver nitrate
    Sci Total Environ, 610-611, 972-982
    DOI 10.1016/j.scitotenv.2017.08.115, PubMed 28838034
  4. Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
    Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
    BMC Cancer, 17 (1), 730
    DOI 10.1186/s12885-017-3737-z, PubMed 29121858
  5. Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
    Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
    ChemMedChem, 12 (8), 613-620
    DOI 10.1002/cmdc.201700108, PubMed 28334511
  6. Hessvik NP, Llorente A (2017)
    Current knowledge on exosome biogenesis and release
    Cell Mol Life Sci, 75 (2), 193-208
    DOI 10.1007/s00018-017-2595-9, PubMed 28733901
  7. Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
    PtdIns3P controls mTORC1 signaling through lysosomal positioning
    J Cell Biol, 216 (12), 4217-4233
    DOI 10.1083/jcb.201611073, PubMed 29030394
  8. Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
    Protection against Shiga Toxins
    Toxins (Basel), 9 (2)
    DOI 10.3390/toxins9020044, PubMed 28165371
  9. Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
    Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
    PLoS One, 12 (1), e0170716
    DOI 10.1371/journal.pone.0170716, PubMed 28114329
  10. Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
    A novel community driven software for functional enrichment analysis of extracellular vesicles data
    J Extracell Vesicles, 6 (1), 1321455
    DOI 10.1080/20013078.2017.1321455, PubMed 28717418
  11. Sadovska L, Zandberga E, Sagini K, Jēkabsons K, Riekstiņa U, Kalniņa Z, Llorente A, Linē A (2017)
    A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication
    Biochem Biophys Res Commun, 495 (2), 1930-1935
    DOI 10.1016/j.bbrc.2017.12.072, PubMed 29248729
  12. Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
    Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
    Exp Cell Res, 357 (1), 67-78
    DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044
  13. Skotland T (2017)
    Injection of nanoparticles into cloven-hoof animals: Asking for trouble
    Theranostics, 7 (19), 4877-4878
    DOI 10.7150/thno.22420, PubMed 29187910
  14. Skotland T, Sandvig K, Llorente A (2017)
    Lipids in exosomes: Current knowledge and the way forward
    Prog Lipid Res, 66, 30-41
    DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
  15. Sulheim E, Iversen TG, To Nakstad V, Klinkenberg G, Sletta H, Schmid R, Hatletveit AR, Wågbø AM, Sundan A, Skotland T, Sandvig K, Mørch Ý (2017)
    Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles
    Int J Mol Sci, 18 (11)
    DOI 10.3390/ijms18112454, PubMed 29156588
  16. Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM (2017)
    A vital sugar code for ricin toxicity
    Cell Res, 27 (11), 1351-1364
    DOI 10.1038/cr.2017.116, PubMed 28925387
  17. Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
    Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
    J Extracell Vesicles, 6 (1), 1344087
    DOI 10.1080/20013078.2017.1344087, PubMed 28804597
  18. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

  1. Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
    Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
    Sci Rep, 6, 30336
    DOI 10.1038/srep30336, PubMed 27458147
  2. Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
    Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
    Oncotarget, 7 (18), 25443-60
    DOI 10.18632/oncotarget.8327, PubMed 27029001
  3. Endzeliņš E, Melne V, Kalniņa Z, Lietuvietis V, Riekstiņa U, Llorente A, Linē A (2016)
    Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review
    Mol Cancer, 15 (1), 41
    DOI 10.1186/s12943-016-0523-5, PubMed 27189160
  4. Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C et al. (2016)
    Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
    ACS Nano, 10 (4), 3886-99
    DOI 10.1021/acsnano.5b08015, PubMed 26978483
  5. Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ (2016)
    A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking
    PLoS One, 11 (6), e0156893
    DOI 10.1371/journal.pone.0156893, PubMed 27300140
  6. Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
    PIKfyve inhibition increases exosome release and induces secretory autophagy
    Cell Mol Life Sci, 73 (24), 4717-4737
    DOI 10.1007/s00018-016-2309-8, PubMed 27438886
  7. Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
    Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
    Oncotarget, 7 (48), 79885-79900
    DOI 10.18632/oncotarget.13089, PubMed 27829218
  8. Li Y, Hessvik NP, Danbolt NC, Holen T (2016)
    A large-scale quantitative EM study on activation of olfactory glands shows no effect of cholinergic agents
    Microscopy (Oxf), 65 (5), 438-443
    DOI 10.1093/jmicro/dfw028, PubMed 27460022
  9. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
    Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
    Data Brief, 7, 1171-1174
    DOI 10.1016/j.dib.2016.03.067, PubMed 27761499
  10. Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
    Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
    Eur J Cancer, 70, 122-132
    DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
  11. Skotland T, Ekroos K, Kavaliauskiene S, Bergan J, Kauhanen D, Lintonen T, Sandvig K (2016)
    Determining the Turnover of Glycosphingolipid Species by Stable-Isotope Tracer Lipidomics
    J Mol Biol, 428 (24 Pt A), 4856-4866
    DOI 10.1016/j.jmb.2016.06.013, PubMed 27363608
  12. Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
    The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
    Oncotarget, 7 (52), 86871-86888
    DOI 10.18632/oncotarget.13508, PubMed 27894086
  13. Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
    Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
    Eur J Pharm Sci, 98, 80-85
    DOI 10.1016/j.ejps.2016.09.023, PubMed 27664330
  14. Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ (2016)
    Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport
    Sci Rep, 6, 22721
    DOI 10.1038/srep22721, PubMed 26949061

Publications 2015

  1. Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
    Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
    PLoS One, 10 (5), e0129214
    DOI 10.1371/journal.pone.0129214, PubMed 26017782
  2. Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
    Novel Furin Inhibitors with Potent Anti-infectious Activity
    ChemMedChem, 10 (7), 1218-31
    DOI 10.1002/cmdc.201500103, PubMed 25974265
  3. Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
    Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
    Biochem J, 470 (1), 23-37
    DOI 10.1042/BJ20141562, PubMed 26251444
  4. Klokk TI, Kavaliauskiene S, Sandvig K (2015)
    Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic
    Cell Mol Life Sci, 73 (6), 1301-16
    DOI 10.1007/s00018-015-2049-1, PubMed 26407609
  5. Kymre L, Simm R, Skotland T, Sandvig K (2015)
    Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
    Pathog Dis, 73 (9), ftv083
    DOI 10.1093/femspd/ftv083, PubMed 26443836
  6. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
    Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
    Biochim Biophys Acta, 1858 (2), 281-8
    DOI 10.1016/j.bbamem.2015.12.003, PubMed 26654782
  7. Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
    Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
    Molecules, 20 (7), 13313-23
    DOI 10.3390/molecules200713313, PubMed 26205056
  8. Słomińska-Wojewódzka M, Sandvig K (2015)
    The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
    Molecules, 20 (6), 9816-46
    DOI 10.3390/molecules20069816, PubMed 26023941
  9. Sokołowska I, Piłka ES, Sandvig K, Węgrzyn G, Słomińska-Wojewódzka M (2015)
    Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
    BMC Cell Biol, 16, 1
    DOI 10.1186/s12860-015-0047-7, PubMed 25655076
  10. Szalai P, Hagen LK, Sætre F, Luhr M, Sponheim M, Øverbye A, Mills IG, Seglen PO, Engedal N (2015)
    Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
    Exp Cell Res, 333 (1), 21-38
    DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710
  11. Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M et al. (2015)
    Biological properties of extracellular vesicles and their physiological functions
    J Extracell Vesicles, 4, 27066
    DOI 10.3402/jev.v4.27066, PubMed 25979354
  12. Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
    Identification of prostate cancer biomarkers in urinary exosomes
    Oncotarget, 6 (30), 30357-76
    DOI 10.18632/oncotarget.4851, PubMed 26196085

Publications 2014

  1. Asp N, Pust S, Sandvig K (2014)
    Flotillin depletion affects ErbB protein levels in different human breast cancer cells
    Biochim Biophys Acta, 1843 (9), 1987-96
    DOI 10.1016/j.bbamcr.2014.04.013, PubMed 24747692
  2. Cordara G, Winter HC, Goldstein IJ, Krengel U, Sandvig K (2014)
    The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis
    Biochem Biophys Res Commun, 447 (4), 586-9
    DOI 10.1016/j.bbrc.2014.04.043, PubMed 24747075
  3. Kvalvaag AS, Pust S, Sandvig K (2014)
    Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
    Commun Integr Biol, 7 (1), e28129
    DOI 10.4161/cib.28129, PubMed 24778763
  4. Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
    Regulation of exosome release by glycosphingolipids and flotillins
    FEBS J, 281 (9), 2214-27
    DOI 10.1111/febs.12775, PubMed 24605801
  5. Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
    The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
    J Biol Chem, 290 (7), 4225-37
    DOI 10.1074/jbc.M114.593962, PubMed 25519911
  6. Sandvig K, Bergan J, Kavaliauskiene S, Skotland T (2014)
    Lipid requirements for entry of protein toxins into cells
    Prog Lipid Res, 54, 1-13
    DOI 10.1016/j.plipres.2014.01.001, PubMed 24462587
  7. Simm R, Ahmad I, Rhen M, Le Guyon S, Römling U (2014)
    Regulation of biofilm formation in Salmonella enterica serovar Typhimurium
    Future Microbiol, 9 (11), 1261-82
    DOI 10.2217/fmb.14.88, PubMed 25437188
  8. Solhaug A, Torgersen ML, Holme JA, Lagadic-Gossmann D, Eriksen GS (2014)
    Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol
    Toxicology, 326, 119-29
    DOI 10.1016/j.tox.2014.10.009, PubMed 25456271
  9. Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ (2014)
    Antibody-mediated inhibition of ricin toxin retrograde transport
    mBio, 5 (2), e00995
    DOI 10.1128/mBio.00995-13, PubMed 24713323

Publications 2013

  1. Bergan J, Skotland T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2013)
    The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells
    PLoS One, 8 (9), e75904
    DOI 10.1371/journal.pone.0075904, PubMed 24098742
  2. Gregers TF, Skånland SS, Wälchli S, Bakke O, Sandvig K (2013)
    BiP negatively affects ricin transport
    Toxins (Basel), 5 (5), 969-82
    DOI 10.3390/toxins5050969, PubMed 23666197
  3. Hessvik NP, Sandvig K, Llorente A (2013)
    Exosomal miRNAs as Biomarkers for Prostate Cancer
    Front Genet, 4, 36
    DOI 10.3389/fgene.2013.00036, PubMed 23519132
  4. Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
    Cell density-induced changes in lipid composition and intracellular trafficking
    Cell Mol Life Sci, 71 (6), 1097-116
    DOI 10.1007/s00018-013-1441-y, PubMed 23921715
  5. Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
    The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
    Traffic, 14 (7), 839-52
    DOI 10.1111/tra.12077, PubMed 23593995
  6. Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
    Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
    Biochim Biophys Acta, 1831 (7), 1302-9
    DOI 10.1016/j.bbalip.2013.04.011, PubMed 24046871
  7. Vörös A, Simm R, Kroeger JK, Kolstø AB (2013)
    Gene transcription from the linear plasmid pBClin15 leads to cell lysis and extracellular DNA-dependent aggregation of Bacillus cereus ATCC 14579 in response to quinolone-induced stress
    Microbiology, 159 (Pt 11), 2283-2293
    DOI 10.1099/mic.0.069674-0, PubMed 24002748

Publications 2012

  1. Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
    Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
    Biochim Biophys Acta, 1819 (11-12), 1154-63
    DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
  2. Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestøl K, Danielsen HE, van Deurs B, Sandvig K (2012)
    Flotillins as regulators of ErbB2 levels in breast cancer
    Oncogene, 32 (29), 3443-51
    DOI 10.1038/onc.2012.357, PubMed 22869152
  3. Sandvig K, Llorente A (2012)
    Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
    Mol Cell Proteomics, 11 (7), M111.012914
    DOI 10.1074/mcp.M111.012914, PubMed 22457534
  4. Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K (2012)
    Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
    PLoS One, 7 (7), e40429
    DOI 10.1371/journal.pone.0040429, PubMed 22792315
  5. Østerud B, Skotland T (2012)
    Doping analyses are not on safe ground
    Tidsskr Nor Laegeforen, 132 (8), 929-30
    DOI 10.4045/tidsskr.12.0252, PubMed 22562317

Publications 2011

  1. Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
    Shiga toxin and its use in targeted cancer therapy and imaging
    Microb Biotechnol, 4 (1), 32-46
    DOI 10.1111/j.1751-7915.2010.00180.x, PubMed 21255370
  2. Iversen TG (2011)
    Nanoparticles hinder intracellular transport
    Trac-Trends Anal. Chem., 30 (10), VII-VIII
  3. Iversen TG, Skotland T, Sandvig K (2011)
    Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
    Nano Today, 6 (2), 176-185
  4. Klokk TI, Lingelem AB, Myrann AG, Sandvig K (2011)
    Role of phospholipase A(2) in retrograde transport of ricin
    Toxins (Basel), 3 (9), 1203-19
    DOI 10.3390/toxins3091203, PubMed 22069763
  5. Sandvig K, Pust S, Skotland T, van Deurs B (2011)
    Clathrin-independent endocytosis: mechanisms and function
    Curr Opin Cell Biol, 23 (4), 413-20
    DOI 10.1016/j.ceb.2011.03.007, PubMed 21466956
  6. Skotland T, Iversen TG, Sandvig K (2011)
    Comment on "short ligands affect modes of QD uptake and elimination in human cells"
    ACS Nano, 5 (10), 7690; author reply 7691-2
    DOI 10.1021/nn2021953, PubMed 22023400
  7. Stratford EW, Castro R, Wennerstrom A, Holm R, Munthe E, Lauvrak S, Bjerkehagen B, Myklebost O (2011)
    Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
    Clin Sarcoma Res, 1 (1), 8
    DOI 10.1186/2045-3329-1-8, PubMed 22612877

Publications 2010

  1. Pust S, Barth H, Sandvig K (2010)
    Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
    Cell Microbiol, 12 (12), 1809-20
    DOI 10.1111/j.1462-5822.2010.01512.x, PubMed 20690924
  2. Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
    Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
    FEBS Lett, 584 (12), 2626-34
    DOI 10.1016/j.febslet.2010.04.008, PubMed 20385131
  3. Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
    The Intracellular Journey of Shiga Toxins
    The Open Toxinology Journal, 3, 3-12
    PublikaID 24
  4. Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
    Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
    FEMS Immunol Med Microbiol, 61 (1), 63-75
    DOI 10.1111/j.1574-695X.2010.00749.x, PubMed 21054580

Publications 2009

  1. Iversen TG, Frerker N, Sandvig K (2009)
    Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
    San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
    PublikaID 29
  2. Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
    Endocytosis and retrograde transport of Shiga toxin
    Toxicon, 56 (7), 1181-5
    DOI 10.1016/j.toxicon.2009.11.021, PubMed 19951719
  3. Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell Signal, 21 (7), 1161-8
    DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168

Publications 2008

  1. Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
    Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
    Histochem Cell Biol, 129 (3), 267-76
    DOI 10.1007/s00418-007-0376-5, PubMed 18193449
  2. Sandvig K, van Deurs B (2008)
    Cell biology: Viruses in camouflage
    Nature, 453 (7194), 466-7
    DOI 10.1038/453466a, PubMed 18497813

Publications 2007

  1. Skånland SS, Wälchli S, Utskarpen A, Wandinger-Ness A, Sandvig K (2007)
    Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
    Traffic, 8 (3), 297-309
    DOI 10.1111/j.1600-0854.2006.00527.x, PubMed 17319803
  2. Spilsberg B, Llorente A, Sandvig K (2007)
    Polyunsaturated fatty acids regulate Shiga toxin transport
    Biochem Biophys Res Commun, 364 (2), 283-8
    DOI 10.1016/j.bbrc.2007.09.126, PubMed 17942073
  3. Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
    Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
    J Biol Chem, 282 (22), 16317-28
    DOI 10.1074/jbc.M610886200, PubMed 17403690

Publications 2006

  1. Grimmer S, Spilsberg B, Hanada K, Sandvig K (2006)
    Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
    Traffic, 7 (9), 1243-53
    DOI 10.1111/j.1600-0854.2006.00456.x, PubMed 16919154
  2. Utskarpen A, Slagsvold HH, Iversen TG, Wälchli S, Sandvig K (2006)
    Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
    Traffic, 7 (6), 663-72
    DOI 10.1111/j.1600-0854.2006.00418.x, PubMed 16683916

Publications 2005

  1. Grimmer S, Ying M, Wälchli S, van Deurs B, Sandvig K (2005)
    Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
    Traffic, 6 (2), 144-56
    DOI 10.1111/j.1600-0854.2005.00258.x, PubMed 15634214
  2. Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
    Shiga toxin regulates its entry in a Syk-dependent manner
    Mol Biol Cell, 17 (3), 1096-109
    DOI 10.1091/mbc.e05-08-0766, PubMed 16371508
  3. Sandvig K, van Deurs B (2005)
    Delivery into cells: lessons learned from plant and bacterial toxins
    Gene Ther, 12 (11), 865-72
    DOI 10.1038/sj.gt.3302525, PubMed 15815697
  4. Spilsberg B, Hanada K, Sandvig K (2005)
    Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
    Biochem Biophys Res Commun, 329 (2), 465-73
    DOI 10.1016/j.bbrc.2005.02.005, PubMed 15737610
  5. Spilsberg B, Sandvig K, Wälchli S (2005)
    Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
    Toxicon, 46 (8), 900-6
    DOI 10.1016/j.toxicon.2005.08.015, PubMed 16260019
  6. Torgersen ML, Lauvrak SU, Sandvig K (2005)
    The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
    FEBS J, 272 (16), 4103-13
    DOI 10.1111/j.1742-4658.2005.04835.x, PubMed 16098193

Publications 2004

  1. Lauvrak SU, Torgersen ML, Sandvig K (2004)
    Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
    J Cell Sci, 117 (Pt 11), 2321-31
    DOI 10.1242/jcs.01081, PubMed 15126632
  2. Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
    Pathways followed by protein toxins into cells
    Int J Med Microbiol, 293 (7-8), 483-90
    DOI 10.1078/1438-4221-00294, PubMed 15149022

Publications 2003

  1. Iversen TG, Skretting G, van Deurs B, Sandvig K (2003)
    Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
    Proc Natl Acad Sci U S A, 100 (9), 5175-80
    DOI 10.1073/pnas.0534231100, PubMed 12682302
  2. Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
    Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
    J Biol Chem, 278 (37), 35850-5
    DOI 10.1074/jbc.M303425200, PubMed 12847103
  3. Sandvig K, van Deurs B (2003)
    Cholera toxin internalization and intoxication - Reply
    J. Cell Sci., 116 (3), 432-433
  4. Spilsberg B, Van Meer G, Sandvig K (2003)
    Role of lipids in the retrograde pathway of ricin intoxication
    Traffic, 4 (8), 544-52
    DOI 10.1034/j.1600-0854.2003.00111.x, PubMed 12839497

Publications 2002

  1. Grimmer S, van Deurs B, Sandvig K (2002)
    Membrane ruffling and macropinocytosis in A431 cells require cholesterol
    J Cell Sci, 115 (Pt 14), 2953-62
    PubMed 12082155
  2. Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
    Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
    J Cell Sci, 115 (Pt 17), 3449-56
    PubMed 12154075
  3. Sandvig K, van Deurs B (2002)
    Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
    FEBS Lett, 529 (1), 49-53
    DOI 10.1016/s0014-5793(02)03182-4, PubMed 12354612
  4. Sandvig K, van Deurs B (2002)
    Membrane traffic exploited by protein toxins
    Annu Rev Cell Dev Biol, 18, 1-24
    DOI 10.1146/annurev.cellbio.18.011502.142107, PubMed 12142266

Publications 2001

  1. Garred Ø, Rodal SK, van Deurs B, Sandvig K (2001)
    Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
    Traffic, 2 (1), 26-36
    DOI 10.1034/j.1600-0854.2001.020105.x, PubMed 11208166
  2. Iversen TG, Skretting G, Llorente A, Nicoziani P, van Deurs B, Sandvig K (2001)
    Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
    Mol Biol Cell, 12 (7), 2099-107
    DOI 10.1091/mbc.12.7.2099, PubMed 11452006
  3. Llorente A, Prydz K, Sprangers M, Skretting G, Kolset SO, Sandvig K (2001)
    Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
    J Cell Sci, 114 (Pt 2), 335-43
    PubMed 11148135
  4. Sandvig K (2001)
    Shiga toxins
    Toxicon, 39 (11), 1629-35
    DOI 10.1016/s0041-0101(01)00150-7, PubMed 11595626
  5. Sandvig K, Grimmer S, Lauvrak SU, Torgersen ML, Skretting G, van Deurs B, Iversen TG (2001)
    Pathways followed by ricin and Shiga toxin into cells
    Histochem Cell Biol, 117 (2), 131-41
    DOI 10.1007/s00418-001-0346-2, PubMed 11935289
  6. Torgersen ML, Skretting G, van Deurs B, Sandvig K (2001)
    Internalization of cholera toxin by different endocytic mechanisms
    J Cell Sci, 114 (Pt 20), 3737-47
    PubMed 11707525

Publications 2000

  1. Grimmer S, Iversen TG, van Deurs B, Sandvig K (2000)
    Endosome to Golgi transport of ricin is regulated by cholesterol
    Mol Biol Cell, 11 (12), 4205-16
    DOI 10.1091/mbc.11.12.4205, PubMed 11102518
  2. Llorente A, van Deurs B, Garred O, Eker P, Sandvig K (2000)
    Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
    J Cell Sci, 113 ( Pt 7), 1213-21
    PubMed 10704372
  3. Nicoziani P, Vilhardt F, Llorente A, Hilout L, Courtoy PJ, Sandvig K, van Deurs B (2000)
    Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
    Mol Biol Cell, 11 (2), 481-95
    DOI 10.1091/mbc.11.2.481, PubMed 10679008
  4. Sandvig K, Grimmer S, Iversen TG, Rodal K, Torgersen ML, Nicoziani P, van Deurs B (2000)
    Ricin transport into cells: studies of endocytosis and intracellular transport
    Int J Med Microbiol, 290 (4-5), 415-20
    DOI 10.1016/S1438-4221(00)80055-7, PubMed 11111920
  5. Sandvig K, Llorente A, Rodal SK, Eker P, Garred O, Stahlhut M, van Deurs B (2000)
    Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
    Eur J Cell Biol, 79 (7), 447-57
    DOI 10.1078/0171-9335-00071, PubMed 10961444
  6. Sandvig K, van Deurs B (2000)
    Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
    EMBO J, 19 (22), 5943-50
    DOI 10.1093/emboj/19.22.5943, PubMed 11080141

Publications 1999

  1. Sandvig K, van Deurs B (1999)
    Endocytosis and intracellular transport of ricin: recent discoveries
    FEBS Lett, 452 (1-2), 67-70
    DOI 10.1016/s0014-5793(99)00529-3, PubMed 10376680

Publications 1998

  1. Llorente A, Rapak A, Schmid SL, van Deurs B, Sandvig K (1998)
    Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
    J Cell Biol, 140 (3), 553-63
    DOI 10.1083/jcb.140.3.553, PubMed 9456316
  2. Llorente A, van Deurs B, Sandvig K (1998)
    Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
    FEBS Lett, 431 (2), 200-4
    DOI 10.1016/s0014-5793(98)00754-6, PubMed 9708902

Publications 1997

  1. Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
    Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
    J Biol Chem, 272 (17), 11414-9
    DOI 10.1074/jbc.272.17.11414, PubMed 9111051
  2. Polesskaia AN, Garred O, Olsnes S, Kozlov IuV (1997)
    [Self-inhibiting N-glycosidase activity of shigella toxin]
    Mol Biol (Mosk), 31 (3), 528-35
    PubMed 9297098
  3. Polesskaya AN, Garred O, Olsnes S, Kozlov YV (1997)
    Self-inhibition of N-glycosidase activity of shiga toxin
    Mol. Biol., 31 (3), 441-447
  4. Sandvig K, Garred O, van Deurs B (1997)
    Intracellular transport and processing of protein toxins produced by enteric bacteria
    Adv Exp Med Biol, 412, 225-32
    DOI 10.1007/978-1-4899-1828-4_34, PubMed 9192018

Publications 1996

  1. Llorente A, Garred O, Holm PK, Eker P, Jacobsen J, van Deurs B, Sandvig K (1996)
    Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
    Exp Cell Res, 227 (2), 298-308
    DOI 10.1006/excr.1996.0279, PubMed 8831568
  2. Sandvig K, Garred O, van Deurs B (1996)
    Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
    Proc Natl Acad Sci U S A, 93 (22), 12339-43
    DOI 10.1073/pnas.93.22.12339, PubMed 8901582
  3. Sandvig K, Garred O, van Helvoort A, van Meer G, van Deurs B (1996)
    Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
    Mol Biol Cell, 7 (9), 1391-404
    DOI 10.1091/mbc.7.9.1391, PubMed 8885234
  4. Sandvig K, van Deurs B (1996)
    Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
    Physiol Rev, 76 (4), 949-66
    DOI 10.1152/physrev.1996.76.4.949, PubMed 8874490

Publications 1995

  1. ERIKSEN S, SAND O, LANZREIN M, SANDVIG K, OLSNES S (1995)
    CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
    Trends Microbiol., 3 (5), 167-168
  2. Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
    Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
    Exp Cell Res, 218 (1), 39-49
    DOI 10.1006/excr.1995.1128, PubMed 7737376
  3. Garred O, van Deurs B, Sandvig K (1995)
    Furin-induced cleavage and activation of Shiga toxin
    J Biol Chem, 270 (18), 10817-21
    DOI 10.1074/jbc.270.18.10817, PubMed 7738018

Publications 1994

  1. SANDVIG K, GARRED O, HOLM PK, VANDEURS B (1994)
    ENTRY OF SHIGA TOXIN INTO CELLS
    INT CONGR SER, 1072, 139-146
  2. Sandvig K, Ryd M, Garred O, Schweda E, Holm PK, van Deurs B (1994)
    Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
    J Cell Biol, 126 (1), 53-64
    DOI 10.1083/jcb.126.1.53, PubMed 8027186
  3. Sandvig K, van Deurs B (1994)
    Endocytosis and intracellular sorting of ricin and Shiga toxin
    FEBS Lett, 346 (1), 99-102
    DOI 10.1016/0014-5793(94)00281-9, PubMed 8206167
  4. Sandvig K, van Deurs B (1994)
    Endocytosis without clathrin
    Trends Cell Biol, 4 (8), 275-7
    DOI 10.1016/0962-8924(94)90211-9, PubMed 14731589
  5. SANDVIG K, VANDEURS B (1994)
    ENTRY OF SHIGA TOXIN INTO CELLS
    ZBL BAKT S, 24, 365-374

Publications 1993

  1. Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, Van Deurs B (1993)
    Entry of Shiga toxin into cells
    Zentralbl Bakteriol, 278 (2-3), 296-305
    DOI 10.1016/s0934-8840(11)80846-7, PubMed 8347933
  2. Sandvig K, Garred O, Holm PK, van Deurs B (1993)
    Endocytosis and intracellular transport of protein toxins
    Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
    DOI 10.1042/bst0210707, PubMed 8224494

Publications 1992

  1. Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
    Protein toxins: mode of action and cell entry
    Biochem Soc Trans, 20 (4), 724-7
    DOI 10.1042/bst0200724, PubMed 1487049
  2. Sandvig K, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
    Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
    Nature, 358 (6386), 510-2
    DOI 10.1038/358510a0, PubMed 1641040
  3. Sandvig K, van Deurs B (1992)
    Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
    Exp Cell Res, 200 (2), 253-62
    DOI 10.1016/0014-4827(92)90171-4, PubMed 1572394

Publications 1991

  1. Sandvig K, Prydz K, Hansen SH, van Deurs B (1991)
    Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
    J Cell Biol, 115 (4), 971-81
    DOI 10.1083/jcb.115.4.971, PubMed 1955466
  2. Sandvig K, Prydz K, Ryd M, van Deurs B (1991)
    Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
    J Cell Biol, 113 (3), 553-62
    DOI 10.1083/jcb.113.3.553, PubMed 1901867
  3. Sandvig K, van Deurs B (1991)
    Endocytosis without clathrin (a minireview)
    Cell Biol Int Rep, 15 (1), 3-8
    DOI 10.1016/0309-1651(91)90077-v, PubMed 1900741

Publications 1990

  1. Sandvig K, van Deurs B (1990)
    Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
    J Biol Chem, 265 (11), 6382-8
    PubMed 1969411

Publications 1989

  1. Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
    Immunotoxins--entry into cells and mechanisms of action
    Immunol Today, 10 (9), 291-5
    PubMed 2686677
  2. OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
    FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
    J. Biol. Chem., 264 (22), 12749-12751
  3. Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
    Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
    J Cell Biol, 108 (4), 1331-43
    DOI 10.1083/jcb.108.4.1331, PubMed 2564398
  4. Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
    Control of coated-pit function by cytoplasmic pH
    Methods Cell Biol, 32, 365-82
    DOI 10.1016/s0091-679x(08)61181-4, PubMed 2575206
  5. van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
    [Endocytosis, intracellular transport and sorting of proteins]
    Nord Med, 104 (1), 9-11
    PubMed 2911460

Publications 1988

  1. Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
    Diphtheria toxin entry: protein translocation in the reverse direction
    Trends Biochem Sci, 13 (9), 348-51
    DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713
  2. Olsnes S, Sandvig K (1988)
    How protein toxins enter and kill cells
    Cancer Treat Res, 37, 39-73
    DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634
  3. Sandvig K, Olsnes S (1988)
    Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
    J Biol Chem, 263 (25), 12352-9
    PubMed 2457582
  4. Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
    Inhibition of endocytosis from coated pits by acidification of the cytosol
    J Cell Biochem, 36 (1), 73-81
    DOI 10.1002/jcb.240360108, PubMed 2893802

Publications 1987

  1. Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
    Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
    J Cell Physiol, 131 (1), 14-22
    DOI 10.1002/jcp.1041310104, PubMed 3032992
  2. Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
    Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
    J Cell Physiol, 131 (1), 6-13
    DOI 10.1002/jcp.1041310103, PubMed 3571337
  3. Moskaug JO, Sandvig K, Olsnes S (1987)
    Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
    J Biol Chem, 262 (21), 10339-45
    PubMed 3112141
  4. Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
    Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
    J Cell Physiol, 132 (2), 192-202
    DOI 10.1002/jcp.1041320203, PubMed 3624315
  5. Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
    Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
    Biochemistry, 26 (10), 2778-85
    DOI 10.1021/bi00384a019, PubMed 3606992
  6. Sandvig K, Brown JE (1987)
    Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
    Infect Immun, 55 (2), 298-303
    DOI 10.1128/IAI.55.2.298-303.1987, PubMed 3542829
  7. Sandvig K, Moskaug JO (1987)
    Pseudomonas toxin binds triton X-114 at low pH
    Biochem J, 245 (3), 899-901
    DOI 10.1042/bj2450899, PubMed 3117052
  8. Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
    Acidification of the cytosol inhibits endocytosis from coated pits
    J Cell Biol, 105 (2), 679-89
    DOI 10.1083/jcb.105.2.679, PubMed 2887575
  9. Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
    Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
    J Cell Physiol, 132 (2), 183-91
    DOI 10.1002/jcp.1041320202, PubMed 3624314
  10. van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
    Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
    Exp Cell Res, 171 (1), 137-52
    DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628
  11. Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
    Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
    Exp Cell Res, 170 (2), 483-90
    DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553

Publications 1986

  1. Olsnes S, Carvajal E, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
    J Biol Chem, 261 (4), 1562-9
    PubMed 3632976
  2. Olsnes S, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
    J Biol Chem, 261 (4), 1553-61
    PubMed 3944101
  3. Olsnes S, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
    J Biol Chem, 261 (4), 1542-52
    PubMed 3944100
  4. Olsnes S, Tønnessen TI, Sandvig K (1986)
    pH-regulated anion antiport in nucleated mammalian cells
    J Cell Biol, 102 (3), 967-71
    DOI 10.1083/jcb.102.3.967, PubMed 3949885
  5. Sandvig K, Olsnes S (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
    J Biol Chem, 261 (4), 1570-5
    PubMed 2418015
  6. SANDVIG K, TONNESSEN TI, SAND O, OLSNES S (1986)
    REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
    J. Biol. Chem., 261 (25), 1639-1644
  7. Sandvig K, Tønnessen TI, Olsnes S (1986)
    Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
    Cancer Res, 46 (12 Pt 1), 6418-22
    PubMed 3096563
  8. Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
    Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
    J Biol Chem, 261 (25), 11639-44
    PubMed 3745160
  9. van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
    Routing of internalized ricin and ricin conjugates to the Golgi complex
    J Cell Biol, 102 (1), 37-47
    DOI 10.1083/jcb.102.1.37, PubMed 3001103

Publications 1985

  1. Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
    Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
    J Cell Physiol, 122 (2), 193-9
    DOI 10.1002/jcp.1041220205, PubMed 3844014
  2. Madshus IH, Sandvig K, Olsnes S (1985)
    Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
    Exp Cell Res, 160 (1), 240-4
    DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095
  3. Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
    Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
    Biochim Biophys Acta, 846 (3), 334-41
    DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483
  4. Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
    Entry mechanisms of protein toxins and picornaviruses
    Biochem Soc Symp, 50, 171-91
    PubMed 3915869
  5. OLSNES S, SANDVIG K, MADSHUS IH, SUNDAN A (1985)
    ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
    Biochem. Soc. Symp. (50), 171-191
  6. Sandvig K, Olsnes S (1985)
    Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
    Biochem J, 228 (2), 521-3
    DOI 10.1042/bj2280521, PubMed 2990449
  7. Sandvig K, Sundan A, Olsnes S (1985)
    Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
    J Cell Physiol, 124 (1), 54-60
    DOI 10.1002/jcp.1041240110, PubMed 3930519
  8. Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
    Properties of volkensin, a toxic lectin from Adenia volkensii
    J Biol Chem, 260 (27), 14589-95
    PubMed 3932357
  9. STIRPE F, BARBIERI L, ABBONDANZA A, FALASCA AI, BROWN ANF, SANDVIG K, OLSNES S, PIHL A (1985)
    PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
    J. Biol. Chem., 260 (27), 4589-4595
  10. van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
    Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
    Exp Cell Res, 159 (2), 287-304
    DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159

Publications 1984

  1. Madshus IH, Olsnes S, Sandvig K (1984)
    Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
    Virology, 139 (2), 346-57
    DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029
  2. Madshus IH, Olsnes S, Sandvig K (1984)
    Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
    J Cell Biol, 98 (4), 1194-200
    DOI 10.1083/jcb.98.4.1194, PubMed 6325467
  3. Madshus IH, Olsnes S, Sandvig K (1984)
    Requirements for entry of poliovirus RNA into cells at low pH
    EMBO J, 3 (9), 1945-50
    DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049
  4. Sandvig K, Madshus IH, Olsnes S (1984)
    Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
    Biochem J, 219 (3), 935-40
    DOI 10.1042/bj2190935, PubMed 6331401
  5. Sandvig K, Olsnes S (1984)
    Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
    J Cell Physiol, 119 (1), 7-14
    DOI 10.1002/jcp.1041190103, PubMed 6707104
  6. Sandvig K, Olsnes S (1984)
    Receptor-mediated entry of protein toxins into cells
    Acta Histochem Suppl, 29, 79-94
    PubMed 6144140
  7. Sandvig K, Sundan A, Olsnes S (1984)
    Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
    J Cell Biol, 98 (3), 963-70
    DOI 10.1083/jcb.98.3.963, PubMed 6699094
  8. Sundan A, Sandvig K, Olsnes S (1984)
    Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
    Cancer Res, 44 (11), 4919-23
    PubMed 6435858
  9. Sundan A, Sandvig K, Olsnes S (1984)
    Calmodulin antagonists sensitize cells to pseudomonas toxin
    J Cell Physiol, 119 (1), 15-22
    DOI 10.1002/jcp.1041190104, PubMed 6707099

Publications 1983

  1. Sundan A, Sandvig K, Olsnes S (1983)
    Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
    Biochem Biophys Res Commun, 117 (2), 562-7
    DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763
  2. Sundan A, Sandvig K, Olsnes S (1983)
    Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
    Biochim Biophys Acta, 761 (3), 296-302
    DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111

Publications 1982

  1. Olsnes S, Haylett T, Sandvig K (1982)
    The toxic lectin modeccin
    Methods Enzymol, 83, 357-62
    DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935
  2. Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
    Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
    J Biol Chem, 257 (22), 13263-70
    PubMed 7142144
  3. Sandvig K, Olsnes S (1982)
    Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
    J Biol Chem, 257 (13), 7495-503
    PubMed 6806276
  4. Sandvig K, Olsnes S (1982)
    Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
    J Biol Chem, 257 (13), 7504-13
    PubMed 7085634
  5. Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
    Action of viscumin, a toxic lectin from mistletoe, on cells in culture
    J Biol Chem, 257 (22), 13271-7
    PubMed 7142145
  6. Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
    Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
    J Biol Chem, 257 (16), 9733-9
    PubMed 7107588

Publications 1981

  1. Sandvig K, Olsnes S (1981)
    Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
    J Biol Chem, 256 (17), 9068-76
    PubMed 7263699
  2. Sandvig K, Olsnes S (1981)
    Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
    Biochem J, 194 (3), 821-7
    DOI 10.1042/bj1940821, PubMed 7306026

Publications 1980

  1. Sandvig K (1980)
    [Intracellular mediators for polypeptide hormones]
    Tidsskr Nor Laegeforen, 100 (15), 1021-23
    PubMed 6250248
  2. Sandvig K (1980)
    [Receptors for polypeptide hormones]
    Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
    PubMed 6250247
  3. Sandvig K, Olsnes S (1980)
    Diphtheria toxin entry into cells is facilitated by low pH
    J Cell Biol, 87 (3 Pt 1), 828-32
    DOI 10.1083/jcb.87.3.828, PubMed 7462324

Publications 1979

  1. Sandvig K, Olsnes S (1979)
    Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
    Exp Cell Res, 121 (1), 15-25
    DOI 10.1016/0014-4827(79)90439-7, PubMed 446525
  2. Sandvig K, Olsnes S, Pihl A (1979)
    Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
    Biochem Biophys Res Commun, 90 (2), 648-55
    DOI 10.1016/0006-291x(79)91284-1, PubMed 508328

Publications 1978

  1. Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
    Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
    J Supramol Struct, 9 (1), 15-25
    DOI 10.1002/jss.400090103, PubMed 732310
  2. Sandvig K (1978)
    Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
    FEBS Lett, 89 (2), 233-6
    DOI 10.1016/0014-5793(78)80225-7, PubMed 658411
  3. Sandvig K, Olsnes S, Pihl A (1978)
    Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
    Eur J Biochem, 88 (1), 307-13
    DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847
  4. Sandvig K, Olsnes S, Pihl A (1978)
    Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
    Eur J Biochem, 82 (1), 13-23
    DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666
  5. Sandvig K, Olsnes S, Pihl A (1978)
    Chemical modifications of the toxic lectins abrin and ricin
    Eur J Biochem, 84 (2), 323-31
    DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792

Publications 1977

  1. Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
    Modeccin--a plant toxin inhibiting protein synthesis
    Biochem Biophys Res Commun, 79 (4), 1176-83
    DOI 10.1016/0006-291x(77)91130-5, PubMed 603653

Publications 1976

  1. Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
    Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
    J Biol Chem, 251 (13), 3985-92
    PubMed 932017
  2. Sandvig K, Olsnes S, Pihl A (1976)
    Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
    J Biol Chem, 251 (13), 3977-84
    PubMed 6468
 
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