OUH - Group members

Rojyar Khezri

Senior engineer
+47 22 78 19 24

Rojyar studied Biochemistry and Molecular Medicine at the University of Oulu, Finland. She did her Master’s thesis in Prof. Sergio Grinstein’s lab with the supervision of Dr. Johnathan Canton at Sick Kids in Toronto, Canada. She, in short time, became fascinated by phagosome maturation and macrophage plasticity. For her PhD project she joined the group of Tor Erik Rusten with the co-supervision of Prof. Harald Stenmark. As a PhD student, she seeks to acquire knowledge on the intriguing topic of systemic responses of cancer cachexia and the role of autophagy using Drosophila melanogaster as a model.

Publications 2022

Holland P, Quintana EM, Khezri R, Schoborg TA, Rusten TE (2022)
Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
Sci Rep, 12 (1), 2056
DOI 10.1038/s41598-022-05991-5, PubMed 35136137

Khezri R, Rusten TE (2022)
Autophagy power expands: fuse those cells!
EMBO J, 41 (12), e111424
DOI 10.15252/embj.2022111424, PubMed 35561082

Publications 2021

Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
EMBO J, 40 (18), e107336
DOI 10.15252/embj.2020107336, PubMed 34309071

Publications 2019

Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE et al. (2019)
NAD⁺ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Nat Commun, 10 (1), 5284
DOI 10.1038/s41467-019-13172-8, PubMed 31754102

Khezri R, Rusten TE (2019)
Autophagy and Tumorigenesis in Drosophila
Adv Exp Med Biol, 1167, 113-127
DOI 10.1007/978-3-030-23629-8_7, PubMed 31520352

Khezri R, Rusten TE (2019)
Correction to: Autophagy and Tumorigenesis in Drosophila
Adv Exp Med Biol, 1167, C1
DOI 10.1007/978-3-030-23629-8_15, PubMed 33306185

Publications 2017

Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876

Publications 2014

Canton J, Khezri R, Glogauer M, Grinstein S (2014)
Contrasting phagosome pH regulation and maturation in human M1 and M2 macrophages
Mol Biol Cell, 25 (21), 3330-41
DOI 10.1091/mbc.E14-05-0967, PubMed 25165138