Kristin Ørstavik

  • Section leader, group leader; MD, PhD
  • +47 924 22 126

Primary Investigator and head of the RND groups adult research.

 

Publications 2024

Solbakken G, Løseth S, Frich JC, Dietrichs E, Ørstavik K (2024)
Small and large fiber neuropathy in adults with myotonic dystrophy type 1
Front Neurol, 15, 1375218
DOI 10.3389/fneur.2024.1375218, PubMed 38504800

Ørstavik K, Rosenberger AD, Fossmo HL, Nordstrøm M, de Visser M (2024)
Multidisciplinary management and care in rare neuromuscular disorders: A call for action
Eur J Neurol, e16265 (in press)
DOI 10.1111/ene.16265, PubMed 38425128

Publications 2023

Aden P, Skarbø AB, Wallace S, Ørstavik K, Rasmussen M (2023)
Cognitive function, behaviour and quality of life in children with myotonic dystrophy type 1 in South - Eastern Norway
Eur J Paediatr Neurol, 45, 1-6
DOI 10.1016/j.ejpn.2023.05.004, PubMed 37209486

Fossmo HL, Ørstavik K, Frich JC, Robinson HS (2023)
Translation, reliability, and validity of the Norwegian version of the ABILHAND-NMD and the ACTIVLIM for Myotonic Dystrophy type 1
Disabil Rehabil, 1-9 (in press)
DOI 10.1080/09638288.2023.2231848, PubMed 37438996

Rasmussen M, Wallace S, Ørstavik K, Popperud T, Ramm-Pettersen A, Førde R (2023)
[Not Available]
Tidsskr Nor Laegeforen, 143 (14)
DOI 10.4045/tidsskr.23.0346, PubMed 37830969

Ørstavik K (2023)
Neuropathic pain - Still a challenge to assess
Eur J Neurol, 30 (8), 2139-2140
DOI 10.1111/ene.15889, PubMed 37218369

Publications 2022

Andries A, Van Walsem MR, Ørstavik K, Frich JC (2022)
Functional Ability and Physical Activity in Hereditary Neuromuscular Diseases
J Neuromuscul Dis, 9 (3), 437-446
DOI 10.3233/JND-210677, PubMed 35180128

Andries A, Ørstavik K, Rueegg CS, Eng S, Edvardsen E, Allen SM, Torsvik IK, Raastad T, Ruud E, Nilsen KB (2022)
Polyneuropathy in Adolescent Childhood Cancer Survivors: The PACCS Study
Pediatr Neurol, 140, 9-17
DOI 10.1016/j.pediatrneurol.2022.11.012, PubMed 36586183

Jensen SM, Müller KI, Mellgren SI, Bindoff LA, Rasmussen M, Ørstavik K, Jonsrud C, Tveten K, Nilssen Ø, Van Ghelue M, Arntzen KA (2022)
Epidemiology and natural history in 101 subjects with FKRP-related limb-girdle muscular dystrophy R9. The Norwegian LGMDR9 cohort study (2020)
Neuromuscul Disord, 33 (2), 119-132
DOI 10.1016/j.nmd.2022.11.005, PubMed 36522254

Lie HC, Anderssen S, Rueegg CS, Raastad T, Grydeland M, Thorsen L, Stensrud T, Edvardsen E, Larsen MH, Torsvik IK, Bovim LP, Götte M, Lähteenmäki PM, Kriemler S, Larsen HB, Fridh MK, Ørstavik K, Brun H, Matthews I, Hornset E, Ruud E (2022)
The Physical Activity and Fitness in Childhood Cancer Survivors (PACCS) Study: Protocol for an International Mixed Methods Study
JMIR Res Protoc, 11 (3), e35838
DOI 10.2196/35838, PubMed 35258456

Rustad CF, Tveten K, Braathen GJ, Merckoll E, Kirkhus E, Fossmo HL, Ørstavik K (2022)
A woman in her fifties with chronic muscle weakness
Tidsskr Nor Laegeforen, 142 (1)
DOI 10.4045/tidsskr.21.0038, PubMed 35026081

Rustad CF, Tveten K, Braathen GJ, Merckoll E, Kirkhus E, Fossmo HL, Ørstavik K (2022)
[Correction: A woman in her fifties with chronic muscle weakness]
Tidsskr Nor Laegeforen, 142 (2)
DOI 10.4045/tidsskr.22.0032, PubMed 35107936

Ørstavik K, Arntzen KA, Mathisen P, Backe PH, Tangeraas T, Rasmussen M, Kristensen E, Van Ghelue M, Jonsrud C, Bliksrud YT (2022)
Novel mutations in the HADHB gene causing a mild phenotype of mitochondrial trifunctional protein (MTP) deficiency
JIMD Rep, 63 (3), 193-198
DOI 10.1002/jmd2.12276, PubMed 35433169

Publications 2021

Pihlstrøm HK, Weedon-Fekjær MS, Bjerkely BL, von der Lippe C, Ørstavik K, Mathisen P, Heimdal K, Jenssen TG, Dahle DO, Solberg OK, Sigurdardottir S (2021)
Health-related quality of life in Norwegian adults with Fabry disease: Disease severity, pain, fatigue and psychological distress
JIMD Rep, 62 (1), 56-69
DOI 10.1002/jmd2.12240, PubMed 34765399

Sigurdardottir S, Bjerkely B, Jenssen TG, Mathisen P, von der Lippe C, Ørstavik K, Heimdal K, Dahle DO, Weedon-Fekjær MS, Solberg O, Pihlstrøm HK (2021)
The impact of demographic and clinical characteristics on the trajectories of health-related quality of life among patients with Fabry disease
Orphanet J Rare Dis, 16 (1), 427
DOI 10.1186/s13023-021-02066-y, PubMed 34641933

Solbakken G, Løseth S, Froholdt A, Eikeland TD, Nærland T, Frich JC, Dietrichs E, Ørstavik K (2021)
Pain in adult myotonic dystrophy type 1: relation to function and gender
BMC Neurol, 21 (1), 101
DOI 10.1186/s12883-021-02124-9, PubMed 33663406

Welland NL, Hæstad H, Fossmo HL, Giltvedt K, Ørstavik K, Nordstrøm M (2021)
The Role of Nutrition and Physical Activity as Trigger Factors of Paralytic Attacks in Primary Periodic Paralysis
J Neuromuscul Dis, 8 (4), 457-468
DOI 10.3233/JND-200604, PubMed 33646174

Publications 2020

Orstavik K, Kirkhus E, Hovland M (2020)
Powerful attachments in a rare condition
Tidsskr. Nor. Laegeforen., 140 (16), 1671

Ørstavik K, Kirkhus E, Hovland M (2020)
[Hypertrophic calves in a rare condition]
Tidsskr Nor Laegeforen, 140 (16)
DOI 10.4045/tidsskr.20.0505, PubMed 33172251

Publications 2019

Allen SM, Bédos Ulvin L, Sabel W, Popperud TH, Ørstavik K (2019)
A painful foot with diagnostic and therapeutic consequences
Scand J Pain, 19 (3), 615-618
DOI 10.1515/sjpain-2019-0015, PubMed 31120861

Miall RC, Rosenthal O, Ørstavik K, Cole JD, Sarlegna FR (2019)
Loss of haptic feedback impairs control of hand posture: a study in chronically deafferented individuals when grasping and lifting objects
Exp Brain Res, 237 (9), 2167-2184
DOI 10.1007/s00221-019-05583-2, PubMed 31209510

Orstavik K (2019)
Oliver Sacks- about remorse, neurologist joy and empathy
Tidsskr. Nor. Laegeforen., 139 (7), 637-640

Solbakken G, Bjørnarå B, Kirkhus E, Nguyen B, Hansen G, Frich JC, Ørstavik K (2019)
MRI of trunk muscles and motor and respiratory function in patients with myotonic dystrophy type 1
BMC Neurol, 19 (1), 135
DOI 10.1186/s12883-019-1357-8, PubMed 31216995

Ørstavik K (2019)
[Oliver Sacks – on regret, the joys of neuroscience literature, and empathy]
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.18.0663, PubMed 30969042

Publications 2018

Arntzen KA, Høyer H, Ørstavik K, Tallaksen C, Vedeler C, Østern R, Nebuchennykh M, Braathen GJ, Fagerheim T (2018)
Charcot-Marie-Tooth disease type 4C in Norway: Clinical characteristics, mutation spectrum and minimum prevalence
Neuromuscul Disord, 28 (8), 639-645
DOI 10.1016/j.nmd.2018.06.004, PubMed 30001926

Fossmo HL, Holtebekk E, Giltvedt K, Dybesland AR, Sanaker PS, Ørstavik K (2018)
Physical exercise in adults with hereditary neuromuscular disease
Tidsskr Nor Laegeforen, 138 (11)
DOI 10.4045/tidsskr.17.1024, PubMed 29947206

Hasselberg NE, Berge KE, Rasmussen M, Früh A, Ørstavik K, Haugaa KH (2018)
[Cardiomyopathy in hereditary muscular dystrophies]
Tidsskr Nor Laegeforen, 138 (1)
DOI 10.4045/tidsskr.16.0683, PubMed 29313627

Jensen SM, Arntzen KA, Orstavik K, Rasmussen M, Bindoff LA (2018)
Common promises for patients with neuromuscular diseases
Tidsskr. Nor. Laegeforen., 138 (15), 1408-1409

Jensen SM, Arntzen KA, Ørstavik K, Rasmussen M, Bindoff LA (2018)
[Not Available]
Tidsskr Nor Laegeforen, 138 (15)
DOI 10.4045/tidsskr.18.0630, PubMed 30277043

Kleggetveit IP, Loseth S, Orstavik K, Eichele T (2018)
Clinical neurophysiology on suspicion of botulism
Tidsskr. Nor. Laegeforen., 138 (9), 800

Kleggetveit IP, Løseth S, Ørstavik K, Eichele T (2018)
[Not Available]
Tidsskr Nor Laegeforen, 138 (9)
DOI 10.4045/tidsskr.18.0373, PubMed 29808649

Miall RC, Kitchen NM, Nam SH, Lefumat H, Renault AG, Ørstavik K, Cole JD, Sarlegna FR (2018)
Proprioceptive loss and the perception, control and learning of arm movements in humans: evidence from sensory neuronopathy
Exp Brain Res, 236 (8), 2137-2155
DOI 10.1007/s00221-018-5289-0, PubMed 29779050

Solheim O, Skalleberg J, Warncke T, Ørstavik K, Tropé C, Fosså SD (2018)
Long-term neurotoxicity and Raynaud's phenomenon in patients treated with cisplatin-based chemotherapy for malignant ovarian germ cell tumor
Acta Obstet Gynecol Scand, 98 (2), 240-249
DOI 10.1111/aogs.13477, PubMed 30289161

Ørstavik K, Rasmussen M, Arntzen KA, Bindoff LA (2018)
[Not Available]
Tidsskr Nor Laegeforen, 138 (14)
DOI 10.4045/tidsskr.18.0580, PubMed 30234257

Publications 2017

Orstavik K, Garfelt B, Leren TP, Saberniak J, Haugaa K, Jonsrud C (2017)
A 50 year old man with proximal power failure and heart disease
Tidsskr. Nor. Laegeforen., 137 (16), 1206-1209

Ørstavik K, Garfelt B, Leren TP, Saberniak J, Haugaa K, Jonsrud C (2017)
[A 50-year-old man with proximal pareses and heart disease]
Tidsskr Nor Laegeforen, 137 (16)
DOI 10.4045/tidsskr.16.0789, PubMed 28871726

Publications 2016

Arntzen KA, Lund I, Rasmussen M, Rønningen KE, Torp TI, Ørstavik K (2016)
[Together for patients with hereditary neuromuscular conditions]
Tidsskr Nor Laegeforen, 136 (14-15), 1198-9
DOI 10.4045/tidsskr.16.0502, PubMed 27554555

Kist AM, Sagafos D, Rush AM, Neacsu C, Eberhardt E, Schmidt R, Lunden LK, Ørstavik K, Kaluza L, Meents J, Zhang Z, Carr TH, Salter H, Malinowsky D, Wollberg P, Krupp J, Kleggetveit IP, Schmelz M, Jørum E, Lampert A, Namer B (2016)
SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing
PLoS One, 11 (9), e0161789
DOI 10.1371/journal.pone.0161789, PubMed 27598514

Loseth S, Mellgren SI, Braekken SK, Orstavik K (2016)
OBITUARY Torberg Torbergsen
Tidsskr. Nor. Laegeforen., 136 (1), 62

Pedurupillay CR, Amundsen SS, Barøy T, Rasmussen M, Blomhoff A, Stadheim BF, Ørstavik K, Holmgren A, Iqbal T, Frengen E, Misceo D, Strømme P (2016)
Clinical and molecular characteristics in three families with biallelic mutations in IGHMBP2
Neuromuscul Disord, 26 (9), 570-5
DOI 10.1016/j.nmd.2016.06.457, PubMed 27450922

Solbakken G, Ørstavik K, Hagen T, Dietrichs E, Naerland T (2016)
Major involvement of trunk muscles in myotonic dystrophy type 1
Acta Neurol Scand, 134 (6), 467-473
DOI 10.1111/ane.12565, PubMed 26984572

Solbakken G, Ørstavik K, Hagen T, Dietrichs E, Nærland T (2016)
Major involvement of trunk muscles in myotonic dystrophy type 1
Acta Neurologica Scandinavica, 1, 1-7
DOI 10.1111/ane.12565, PublikaID 229

Publications 2015

Halvorsen JA, Ørstavik K (2015)
[A woman in her 60s with itching arms]
Tidsskr Nor Laegeforen, 135 (16), 1459-61
DOI 10.4045/tidsskr.15.0223, PubMed 26356457

Halvorsen JA, Ørstavik K (2015)
[J.A. Halvorsen & K. Ørstavik reply]
Tidsskr Nor Laegeforen, 135 (20), 1816
DOI 10.4045/tidsskr.15.1077, PubMed 26534802

Namer B, Ørstavik K, Schmidt R, Kleggetveit IP, Weidner C, Mørk C, Kvernebo MS, Kvernebo K, Salter H, Carr TH, Segerdahl M, Quiding H, Waxman SG, Handwerker HO, Torebjörk HE, Jørum E, Schmelz M (2015)
Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7
Pain, 156 (9), 1637-1646
DOI 10.1097/j.pain.0000000000000229, PubMed 25993546

Ørstavik K, Wallace SC, Torbergsen T, Abicht A, Erik Tangsrud S, Kerty E, Rasmussen M (2015)
A de novo Mutation in the SCN4A Gene Causing Sodium Channel Myotonia
J Neuromuscul Dis, 2 (2), 181-184
DOI 10.3233/JND-150069, PubMed 27858731

Publications 2014

Namer B, Schick M, Kleggetveit IP, Ørstavik K, Schmidt R, Jorum E, Torebjörk E, Handwerker H, Schmelz M (2014)
Differential sensitization of silent nociceptors to low pH stimulation by prostaglandin E2 in human volunteers
Eur J Pain, 19 (2), 159-66
DOI 10.1002/ejp.532, PubMed 24890616

Zhang Z, Schmelz M, Segerdahl M, Quiding H, Centerholt C, Juréus A, Carr TH, Whiteley J, Salter H, Kvernebo MS, Ørstavik K, Helås T, Kleggetveit IP, Lunden LK, Jørum E (2014)
Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia
Scand J Pain, 5 (4), 217-225
DOI 10.1016/j.sjpain.2014.09.002, PubMed 29911575

Publications 2013

Jørum E, Warncke T, Ørstavik K (2013)
[Small-fibre neuropathy]
Tidsskr Nor Laegeforen, 133 (2), 179-83
DOI 10.4045/tidsskr.12.0160, PubMed 23344604

Ørstavik K, Kleggetveit IP, Jørum E (2013)
[Microneurography and research on peripheral neuropathic pain]
Tidsskr Nor Laegeforen, 133 (3), 302-5
DOI 10.4045/tidsskr.12.0098, PubMed 23381167

Publications 2012

Kleggetveit IP, Namer B, Schmidt R, Helås T, Rückel M, Ørstavik K, Schmelz M, Jørum E (2012)
High spontaneous activity of C-nociceptors in painful polyneuropathy
Pain, 153 (10), 2040-2047
DOI 10.1016/j.pain.2012.05.017, PubMed 22986070

Ørstavik K, Svalheim S, Gunnarsson R, Gilboe IM, Torbergsen T (2012)
[A seriously ill patient who does not wake up after mechanical ventilation]
Tidsskr Nor Laegeforen, 132 (7), 822-5
DOI 10.4045/tidsskr.11.0357, PubMed 22511094

Østern R, Fagerheim T, Ørstavik K, Holmøy T, Heiberg A, Lund-Petersen I, Strom TM, Nilssen Ø, Dahl A (2012)
Hereditary motor neuron disease in a large Norwegian family with a "H46R" substitution in the superoxide dismutase 1 gene
Neuromuscul Disord, 22 (6), 511-21
DOI 10.1016/j.nmd.2012.01.011, PubMed 22475618

Publications 2009

Orstavik K, Jørum E (2009)
Microneurographic findings of relevance to pain in patients with erythromelalgia and patients with diabetic neuropathy
Neurosci Lett, 470 (3), 180-4
DOI 10.1016/j.neulet.2009.05.061, PubMed 19481586

Publications 2008

Namer B, Barta B, Ørstavik K, Schmidt R, Carr R, Schmelz M, Handwerker HO (2008)
Microneurographic assessment of C-fibre function in aged healthy subjects
J Physiol, 587 (2), 419-28
DOI 10.1113/jphysiol.2008.162941, PubMed 19064617

Publications 2007

Namer B, Hilliges M, Ørstavik K, Schmidt R, Weidner C, Torebjörk E, Handwerker H, Schmelz M (2007)
Endothelin 1 activates and sensitizes human C-nociceptors
Pain, 137 (1), 41-49
DOI 10.1016/j.pain.2007.08.008, PubMed 17884295

Ørstavik K (2007)
Small-fiber dysfunction in patients with chronic painful conditions: assessment of function through clinical, psychophysical and neurophysiological methods including direct microneurographic recordings
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 464, 1 b. (flere pag.)
BIBSYS 070104646

Publications 2006

Jørum E, Ørstavik K, Schmidt R, Namer B, Carr RW, Kvarstein G, Hilliges M, Handwerker H, Torebjörk E, Schmelz M (2006)
Catecholamine-induced excitation of nociceptors in sympathetically maintained pain
Pain, 127 (3), 296-301
DOI 10.1016/j.pain.2006.08.022, PubMed 16997471

Ørstavik K, Namer B, Schmidt R, Schmelz M, Hilliges M, Weidner C, Carr RW, Handwerker H, Jørum E, Torebjörk HE (2006)
Abnormal function of C-fibers in patients with diabetic neuropathy
J Neurosci, 26 (44), 11287-94
DOI 10.1523/JNEUROSCI.2659-06.2006, PubMed 17079656

Ørstavik K, Norheim I, Jørum E (2006)
Pain and small-fiber neuropathy in patients with hypothyroidism
Neurology, 67 (5), 786-91
DOI 10.1212/01.wnl.0000234035.13779.4a, PubMed 16966538

Publications 2004

Ørstavik K, Jørum E (2004)
Diabetesnevropati
In Diabeteshåndboken, Gyldendal akademisk, Oslo, s. 276-283
BIBSYS 041965361

Ørstavik K, Mørk C, Kvernebo K, Jørum E (2004)
Pain in primary erythromelalgia--a neuropathic component?
Pain, 110 (3), 531-538
DOI 10.1016/j.pain.2004.03.030, PubMed 15288393

Page visits: 10973