
Torbjørn Elvsåshagen
- Group leader and postdoctoral researcher; MD, PhD
Publications 2023
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants
Psychol Med, 1-11 (in press)
DOI 10.1017/S0033291723000223, PubMed 36846964
Relationship between function and structure in the visual cortex in healthy individuals and in patients with severe mental disorders
Psychiatry Res Neuroimaging, 332, 111633
DOI 10.1016/j.pscychresns.2023.111633, PubMed 37028226
Corrigendum to "Sleep and sleep deprivation differentially alter white matter microstructure: A mixed model design utilising advanced diffusion modelling"
Neuroimage, 270, 119939
DOI 10.1016/j.neuroimage.2023.119939, PubMed 36841108
Baseline long-term potentiation-like cortical plasticity is associated with longitudinal cortical thinning in healthy adults and in adults with bipolar disorder type II
Eur J Neurosci (in press)
DOI 10.1111/ejn.16038, PubMed 37163975
Publications 2022
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Nat Neurosci, 25 (4), 421-432
DOI 10.1038/s41593-022-01042-4, PubMed 35383335
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
A family study of symbolic learning and synaptic plasticity in autism spectrum disorder
Front Hum Neurosci, 16, 950922
DOI 10.3389/fnhum.2022.950922, PubMed 36504626
Long-Term Potentiation-Like Visual Synaptic Plasticity Is Negatively Associated With Self-Reported Symptoms of Depression and Stress in Healthy Adults
Front Hum Neurosci, 16, 867675
DOI 10.3389/fnhum.2022.867675, PubMed 35601905
Long term potentiation-like neural plasticity and performance-based memory function
Neurobiol Learn Mem, 196, 107696
DOI 10.1016/j.nlm.2022.107696, PubMed 36368635
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Evidence for widespread alterations in cortical microstructure after 32 h of sleep deprivation
Transl Psychiatry, 12 (1), 161
DOI 10.1038/s41398-022-01909-x, PubMed 35422097
Publications 2021
Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group
Biol Psychiatry, 91 (6), 582-592
DOI 10.1016/j.biopsych.2021.09.008, PubMed 34809987
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J Affect Disord, 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
The genetic architecture of the human thalamus and its overlap with ten common brain disorders
Nat Commun, 12 (1), 2909
DOI 10.1038/s41467-021-23175-z, PubMed 34006833
Characterisation of age and polarity at onset in bipolar disorder
Br J Psychiatry, 219 (6), 659-669
DOI 10.1192/bjp.2021.102, PubMed 35048876
Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals
Bipolar Disord, 24 (5), 509-520
DOI 10.1111/bdi.13172, PubMed 34894200
Association between body mass index and subcortical brain volumes in bipolar disorders-ENIGMA study in 2735 individuals
Mol Psychiatry, 26 (11), 6806-6819
DOI 10.1038/s41380-021-01098-x, PubMed 33863996
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
DOI 10.1038/s41588-021-00857-4, PubMed 34002096
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Transl Psychiatry, 11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458
Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity
Brain Behav, 11 (8), e02188
DOI 10.1002/brb3.2188, PubMed 34291596
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379
ENIGMA-Sleep: Challenges, opportunities, and the road map
J Sleep Res, 30 (6), e13347
DOI 10.1111/jsr.13347, PubMed 33913199
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
Schizophr Bull, 47 (6), 1751-1760
DOI 10.1093/schbul/sbab049, PubMed 33963856
Publications 2020
Heart rate variability is associated with disease severity in psychosis spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 111, 110108
DOI 10.1016/j.pnpbp.2020.110108, PubMed 32946948
Borderline patients have difficulties describing feelings; bipolar II patients describe difficult feelings. An alexithymia study
Acta Psychiatr Scand, 142 (3), 203-214
DOI 10.1111/acps.13204, PubMed 32594515
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849
Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study
BMC Psychiatry, 20 (1), 582
DOI 10.1186/s12888-020-02968-4, PubMed 33287748
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Mol Psychiatry, 26 (9), 5124-5139
DOI 10.1038/s41380-020-0754-0, PubMed 32424236
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
Do visual and auditory stimulus-specific response modulation reflect different mechanisms of neocortical plasticity?
Eur J Neurosci, 53 (4), 1072-1085
DOI 10.1111/ejn.14964, PubMed 32897598
Exploring neurophysiological markers of visual perspective taking: Methodological considerations
Int J Psychophysiol, 161, 1-12
DOI 10.1016/j.ijpsycho.2020.12.006, PubMed 33388368
Experience-dependent modulation of the visual evoked potential: Testing effect sizes, retention over time, and associations with age in 415 healthy individuals
Neuroimage, 223, 117302
DOI 10.1016/j.neuroimage.2020.117302, PubMed 32828930
Sleep and sleep deprivation differentially alter white matter microstructure: A mixed model design utilising advanced diffusion modelling
Neuroimage, 226, 117540
DOI 10.1016/j.neuroimage.2020.117540, PubMed 33186715
Evidence for wakefulness-related changes to extracellular space in human brain white matter from diffusion-weighted MRI
Neuroimage, 212, 116682
DOI 10.1016/j.neuroimage.2020.116682, PubMed 32114147
Publications 2019
Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar II disorder
Acta Psychiatr Scand, 139 (3), 256-268
DOI 10.1111/acps.12997, PubMed 30552759
Equivalence Class Formation and the N400: Methodological Issues
Psychol. Rec., 69 (2), 175-191
DOI 10.1007/s40732-019-00332-x
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
Front Psychiatry, 10, 534
DOI 10.3389/fpsyt.2019.00534, PubMed 31440172
Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Cereb Cortex, 29 (2), 875-891
DOI 10.1093/cercor/bhy291, PubMed 30475994
Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Acta Psychiatr Scand, 139 (4), 348-360
DOI 10.1111/acps.13008, PubMed 30697685
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
DOI 10.1038/s41588-019-0397-8, PubMed 31043756
Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II
Bipolar Disord, 21 (6), 525-538
DOI 10.1111/bdi.12771, PubMed 30864260
Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
DOI 10.1038/s41398-019-0432-7, PubMed 30898995
Publications 2018
Cerebral blood flow changes after a day of wake, sleep, and sleep deprivation
Neuroimage, 186, 497-509
DOI 10.1016/j.neuroimage.2018.11.032, PubMed 30471387
Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Mol Psychiatry, 25 (9), 2130-2143
DOI 10.1038/s41380-018-0228-9, PubMed 30171211
Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals
Transl Psychiatry, 8 (1), 103
DOI 10.1038/s41398-018-0151-5, PubMed 29795193
Publications 2017
Evidence for cortical structural plasticity in humans after a day of waking and sleep deprivation
Neuroimage, 156, 214-223
DOI 10.1016/j.neuroimage.2017.05.027, PubMed 28526620
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Mol Psychiatry, 23 (4), 932-942
DOI 10.1038/mp.2017.73, PubMed 28461699
Oxytocin system dysfunction as a common mechanism underlying metabolic syndrome and psychiatric symptoms in schizophrenia and bipolar disorders
Front Neuroendocrinol, 45, 1-10
DOI 10.1016/j.yfrne.2016.12.004, PubMed 28049009
Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
PLoS One, 12 (2), e0170921
DOI 10.1371/journal.pone.0170921, PubMed 28151944
Dose-dependent social-cognitive effects of intranasal oxytocin delivered with novel Breath Powered device in adults with autism spectrum disorder: a randomized placebo-controlled double-blind crossover trial
Transl Psychiatry, 7 (5), e1136
DOI 10.1038/tp.2017.103, PubMed 28534875
Publications 2016
Dentate gyrus-cornu ammonis (CA) 4 volume is decreased and associated with depressive episodes and lipid peroxidation in bipolar II disorder: Longitudinal and cross-sectional analyses
Bipolar Disord, 18 (8), 657-668
DOI 10.1111/bdi.12457, PubMed 27995733
Subcortical volumetric abnormalities in bipolar disorder
Mol Psychiatry, 21 (12), 1710-1716
DOI 10.1038/mp.2015.227, PubMed 26857596
Publications 2015
Widespread changes in white matter microstructure after a day of waking and sleep deprivation
PLoS One, 10 (5), e0127351
DOI 10.1371/journal.pone.0127351, PubMed 26020651
The brain functional connectome is robustly altered by lack of sleep
Neuroimage, 127, 324-332
DOI 10.1016/j.neuroimage.2015.12.028, PubMed 26712339
Publications 2014
Different impulsivity profiles in borderline personality disorder and bipolar II disorder
J Affect Disord, 170, 104-11
DOI 10.1016/j.jad.2014.08.033, PubMed 25237733
Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder
J Psychiatry Neurosci, 39 (2), 127-34
DOI 10.1503/jpn.130070, PubMed 24309162
The surface area of early visual cortex predicts the amplitude of the visual evoked potential
Brain Struct Funct, 220 (2), 1229-36
DOI 10.1007/s00429-013-0703-7, PubMed 24415060
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358
Publications 2013
Regional cortical thinning may be a biological marker for borderline personality disorder
Acta Psychiatr Scand, 130 (3), 193-204
DOI 10.1111/acps.12234, PubMed 24571788
Evidence for reduced dentate gyrus and fimbria volume in bipolar II disorder
Bipolar Disord, 15 (2), 167-76
DOI 10.1111/bdi.12046, PubMed 23317454
Bipolar II disorder is associated with thinning of prefrontal and temporal cortices involved in affect regulation
Bipolar Disord, 15 (8), 855-64
DOI 10.1111/bdi.12117, PubMed 23980618
Publications 2011
Evidence for impaired neocortical synaptic plasticity in bipolar II disorder
Biol Psychiatry, 71 (1), 68-74
DOI 10.1016/j.biopsych.2011.09.026, PubMed 22036034
The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
J Affect Disord, 135 (1-3), 43-50
DOI 10.1016/j.jad.2011.08.006, PubMed 21880373
Publications 2009
[Neurofibromatosis type 2 and auditory brainstem implantation]
Tidsskr Nor Laegeforen, 129 (15), 1469-73
DOI 10.4045/tidsskr.08.0151, PubMed 19690597
Publications 2008
[Structural plasticity in the adult central nervous system]
Tidsskr Nor Laegeforen, 128 (3), 298-302
PubMed 18264154
[A 58-year-old woman with stroke, elevated troponin and hypercoagulability]
Tidsskr Nor Laegeforen, 128 (6), 706-8
PubMed 18365333