
Tobias Kaufmann
- Researcher; PhD
Publications 2020
Patterns of sociocognitive stratification and perinatal risk in the child brain
Proc Natl Acad Sci U S A, 117 (22), 12419-12427
DOI 10.1073/pnas.2001517117, PubMed 32409600
Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging
Hum Brain Mapp
DOI 10.1002/hbm.25316, PubMed 33314530
Identification of Reproducible BCL11A Alterations in Schizophrenia Through Individual-Level Prediction of Coexpression
Schizophr Bull, 46 (5), 1165-1171
DOI 10.1093/schbul/sbaa047, PubMed 32232389
Genetic control of variability in subcortical and intracranial volumes
Mol Psychiatry
DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study
Neuroimage, 222, 117292
DOI 10.1016/j.neuroimage.2020.117292, PubMed 32835819
The maternal brain: Region-specific patterns of brain aging are traceable decades after childbirth
Hum Brain Mapp, 41 (16), 4718-4729
DOI 10.1002/hbm.25152, PubMed 32767637
Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease
Hum Brain Mapp, 41 (18), 5141-5150
DOI 10.1002/hbm.25180, PubMed 32856754
Functional brain network modeling in sub-acute stroke patients and healthy controls during rest and continuous attentive tracking
Heliyon, 6 (9), e04854
DOI 10.1016/j.heliyon.2020.e04854, PubMed 32995596
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
Cortical thickness and resting-state cardiac function across the lifespan: A cross-sectional pooled mega-analysis
Psychophysiology, e13688
DOI 10.1111/psyp.13688, PubMed 33037836
Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population
PLoS One, 15 (4), e0232292
DOI 10.1371/journal.pone.0232292, PubMed 32343744
Differences in directed functional brain connectivity related to age, sex and mental health
Hum Brain Mapp, 41 (15), 4173-4186
DOI 10.1002/hbm.25116, PubMed 32613721
Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study
Hum Brain Mapp, 41 (16), 4676-4690
DOI 10.1002/hbm.25149, PubMed 32744409
Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents
Transl Psychiatry, 10 (1), 251
DOI 10.1038/s41398-020-00931-1, PubMed 32710012
Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders
Hum Brain Mapp
DOI 10.1002/hbm.25323, PubMed 33340180
Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap
Mol Psychiatry
DOI 10.1038/s41380-020-00915-z, PubMed 33060817
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 692-695
DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 5 (12), 1095-1103
DOI 10.1016/j.bpsc.2020.06.014, PubMed 32859549
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
Cereb Cortex, 30 (10), 5597-5603
DOI 10.1093/cercor/bhaa146, PubMed 32483632
Author Correction: Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 4700
DOI 10.1038/s41467-020-18628-w, PubMed 32929091
Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 3512
DOI 10.1038/s41467-020-17368-1, PubMed 32665545
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
JAMA Psychiatry, 77 (4), 420-430
DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Publications 2019
Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
DOI 10.1038/s41398-019-0432-7, PubMed 30898995
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
JAMA Psychiatry, 76 (7), 739-748
DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Population-based neuroimaging reveals traces of childbirth in the maternal brain
Proc Natl Acad Sci U S A, 116 (44), 22341-22346
DOI 10.1073/pnas.1910666116, PubMed 31615888
Cross-Sectional and Longitudinal MRI Brain Scans Reveal Accelerated Brain Aging in Multiple Sclerosis
Front Neurol, 10, 450
DOI 10.3389/fneur.2019.00450, PubMed 31114541
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Multimodal fusion of structural and functional brain imaging in depression using linked independent component analysis
Hum Brain Mapp, 41 (1), 241-255
DOI 10.1002/hbm.24802, PubMed 31571370
Brain Connectome Mapping of Complex Human Traits and Their Polygenic Architecture Using Machine Learning
Biol Psychiatry, 87 (8), 717-726
DOI 10.1016/j.biopsych.2019.10.011, PubMed 31858985
Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
Front Psychiatry, 10, 534
DOI 10.3389/fpsyt.2019.00534, PubMed 31440172
Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence
Biol Psychiatry, 86 (1), 65-75
DOI 10.1016/j.biopsych.2019.01.019, PubMed 30850129
Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging
Hum Brain Mapp, 41 (3), 697-709
DOI 10.1002/hbm.24833, PubMed 31652017
Oxytocin pathway gene networks in the human brain
Nat Commun, 10 (1), 668
DOI 10.1038/s41467-019-08503-8, PubMed 30737392
Brain age prediction in stroke patients: Highly reliable but limited sensitivity to cognitive performance and response to cognitive training
Neuroimage Clin, 25, 102159
DOI 10.1016/j.nicl.2019.102159, PubMed 31927499
Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder
Transl Psychiatry, 9 (1), 12
DOI 10.1038/s41398-018-0225-4, PubMed 30664633
Population-Based Mapping of Polygenic Risk for Schizophrenia on the Human Brain: New Opportunities to Capture the Dimensional Aspects of Severe Mental Disorders
Biol Psychiatry, 86 (7), 499-501
DOI 10.1016/j.biopsych.2019.08.001, PubMed 31521208
Publications 2018
Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents
JAMA Psychiatry, 75 (3), 287-295
DOI 10.1001/jamapsychiatry.2017.4277, PubMed 29365026
Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories
Eur J Hum Genet, 26 (7), 1049-1059
DOI 10.1038/s41431-018-0134-2, PubMed 29700391
Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia
JAMA Psychiatry, 75 (7), 749-751
DOI 10.1001/jamapsychiatry.2018.0844, PubMed 29799905
Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence
eNeuro, 5 (4)
DOI 10.1523/ENEURO.0092-18.2018, PubMed 30073200
An augmented aging process in brain white matter in HIV
Hum Brain Mapp, 39 (6), 2532-2540
DOI 10.1002/hbm.24019, PubMed 29488278
Data-Driven Clustering Reveals a Link Between Symptoms and Functional Brain Connectivity in Depression
Biol Psychiatry Cogn Neurosci Neuroimaging, 4 (1), 16-26
DOI 10.1016/j.bpsc.2018.05.005, PubMed 29980494
Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast
Biol Psychiatry, 85 (5), 389-398
DOI 10.1016/j.biopsych.2018.09.027, PubMed 30447910
Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Mol Psychiatry, 25 (9), 2130-2143
DOI 10.1038/s41380-018-0228-9, PubMed 30171211
Low-dose intranasal oxytocin delivered with Breath Powered device modulates pupil diameter and amygdala activity: a randomized controlled pupillometry and fMRI study
Neuropsychopharmacology, 44 (2), 306-313
DOI 10.1038/s41386-018-0241-3, PubMed 30323359
Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry
PeerJ, 6, e5908
DOI 10.7717/peerj.5908, PubMed 30533290
Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder
Brain Imaging Behav, 12 (3), 640-652
DOI 10.1007/s11682-017-9714-y, PubMed 28444556
Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 584-602
DOI 10.1038/s41380-018-0118-1, PubMed 30283035
White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging
Sci Rep, 8 (1), 14129
DOI 10.1038/s41598-018-32355-9, PubMed 30237410
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
Mol Psychiatry, 25 (11), 3053-3065
DOI 10.1038/s41380-018-0262-7, PubMed 30279459
Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models
JAMA Psychiatry, 75 (11), 1146-1155
DOI 10.1001/jamapsychiatry.2018.2467, PubMed 30304337
Publications 2017
Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum
Sci Rep, 7, 40268
DOI 10.1038/srep40268, PubMed 28074926
Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer's disease spectrum
Sci Rep, 7, 45131
DOI 10.1038/srep45131, PubMed 28338052
Distinguishing early and late brain aging from the Alzheimer's disease spectrum: consistent morphological patterns across independent samples
Neuroimage, 158, 282-295
DOI 10.1016/j.neuroimage.2017.06.070, PubMed 28666881
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
Neuroimage Clin, 15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Increased sensitivity to age-related differences in brain functional connectivity during continuous multiple object tracking compared to resting-state
Neuroimage, 148, 364-372
DOI 10.1016/j.neuroimage.2017.01.048, PubMed 28111190
Predicting Outcome 12 Months after Mild Traumatic Brain Injury in Patients Admitted to a Neurosurgery Service
Front Neurol, 8, 125
DOI 10.3389/fneur.2017.00125, PubMed 28443058
White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury
Sci Rep, 7 (1), 13795
DOI 10.1038/s41598-017-13628-1, PubMed 29061970
Delayed stabilization and individualization in connectome development are related to psychiatric disorders
Nat Neurosci, 20 (4), 513-515
DOI 10.1038/nn.4511, PubMed 28218917
Increased default-mode variability is related to reduced task-performance and is evident in adults with ADHD
Neuroimage Clin, 16, 369-382
DOI 10.1016/j.nicl.2017.03.008, PubMed 28861338
Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
PLoS One, 12 (2), e0170921
DOI 10.1371/journal.pone.0170921, PubMed 28151944
Consistent Functional Connectivity Alterations in Schizophrenia Spectrum Disorder: A Multisite Study
Schizophr Bull, 43 (4), 914-924
DOI 10.1093/schbul/sbw145, PubMed 27872268
Publications 2016
Age-related differences in brain network activation and co-activation during multiple object tracking
Brain Behav, 6 (11), e00533
DOI 10.1002/brb3.533, PubMed 27843692
Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders
Neuroimage Clin, 12, 389-96
DOI 10.1016/j.nicl.2016.08.012, PubMed 27622135
Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets
Neuroimage, 147, 243-252
DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665
Resting-state high-frequency heart rate variability is related to respiratory frequency in individuals with severe mental illness but not healthy controls
Sci Rep, 6, 37212
DOI 10.1038/srep37212, PubMed 27853244
Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within-subjects randomized dose-response fMRI trial
Psychoneuroendocrinology, 69, 180-8
DOI 10.1016/j.psyneuen.2016.04.010, PubMed 27107209
Global brain connectivity alterations in patients with schizophrenia and bipolar spectrum disorders
J Psychiatry Neurosci, 41 (5), 331-41
DOI 10.1503/jpn.150159, PubMed 26854755
Clinical Utility of Mindfulness Training in the Treatment of Fatigue After Stroke, Traumatic Brain Injury and Multiple Sclerosis: A Systematic Literature Review and Meta-analysis
Front Psychol, 7, 912
DOI 10.3389/fpsyg.2016.00912, PubMed 27445888
Brain connectivity aberrations in anabolic-androgenic steroid users
Neuroimage Clin, 13, 62-69
DOI 10.1016/j.nicl.2016.11.014, PubMed 27942448
Publications 2015
Attentional load modulates large-scale functional brain connectivity beyond the core attention networks
Neuroimage, 109, 260-72
DOI 10.1016/j.neuroimage.2015.01.026, PubMed 25595500
Functional connectivity indicates differential roles for the intraparietal sulcus and the superior parietal lobule in multiple object tracking
Neuroimage, 123, 129-37
DOI 10.1016/j.neuroimage.2015.08.029, PubMed 26299796
Cognitive Effort and Schizophrenia Modulate Large-Scale Functional Brain Connectivity
Schizophr Bull, 41 (6), 1360-9
DOI 10.1093/schbul/sbv013, PubMed 25731885
Long-term independent brain-computer interface home use improves quality of life of a patient in the locked-in state: a case study
Arch Phys Med Rehabil, 96 (3 Suppl), S16-26
DOI 10.1016/j.apmr.2014.03.035, PubMed 25721543
The brain functional connectome is robustly altered by lack of sleep
Neuroimage, 127, 324-332
DOI 10.1016/j.neuroimage.2015.12.028, PubMed 26712339
Disintegration of Sensorimotor Brain Networks in Schizophrenia
Schizophr Bull, 41 (6), 1326-35
DOI 10.1093/schbul/sbv060, PubMed 25943122
The WIN-speller: a new intuitive auditory brain-computer interface spelling application
Front Neurosci, 9, 346
DOI 10.3389/fnins.2015.00346, PubMed 26500476
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
PLoS One, 10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050
Publications 2014
Visuo-motor coordination ability predicts performance with brain-computer interfaces controlled by modulation of sensorimotor rhythms (SMR)
Front Hum Neurosci, 8, 574
DOI 10.3389/fnhum.2014.00574, PubMed 25147518
Toward brain-computer interface based wheelchair control utilizing tactually-evoked event-related potentials
J Neuroeng Rehabil, 11, 7
DOI 10.1186/1743-0003-11-7, PubMed 24428900
Beyond maximum speed--a novel two-stimulus paradigm for brain-computer interfaces based on event-related potentials (P300-BCI)
J Neural Eng, 11 (5), 056004
DOI 10.1088/1741-2560/11/5/056004, PubMed 25080406
The user-centered design as novel perspective for evaluating the usability of BCI-controlled applications
PLoS One, 9 (12), e112392
DOI 10.1371/journal.pone.0112392, PubMed 25469774
Molecular recognition of surface-immobilized carbohydrates by a synthetic lectin
Beilstein J Org Chem, 10, 1354-64
DOI 10.3762/bjoc.10.138, PubMed 24991289
Publications 2013
Cortical effects of user training in a motor imagery based brain-computer interface measured by fNIRS and EEG
Neuroimage, 85 Pt 1, 432-44
DOI 10.1016/j.neuroimage.2013.04.097, PubMed 23651839
Comparison of tactile, auditory, and visual modality for brain-computer interface use: a case study with a patient in the locked-in state
Front Neurosci, 7, 129
DOI 10.3389/fnins.2013.00129, PubMed 23898236
Publications 2012
The changing face of P300 BCIs: a comparison of stimulus changes in a P300 BCI involving faces, emotion, and movement
PLoS One, 7 (11), e49688
DOI 10.1371/journal.pone.0049688, PubMed 23189154
Face stimuli effectively prevent brain-computer interface inefficiency in patients with neurodegenerative disease
Clin Neurophysiol, 124 (5), 893-900
DOI 10.1016/j.clinph.2012.11.006, PubMed 23246415
Spelling is Just a Click Away - A User-Centered Brain-Computer Interface Including Auto-Calibration and Predictive Text Entry
Front Neurosci, 6, 72
DOI 10.3389/fnins.2012.00072, PubMed 22833713
Chemically orthogonal trifunctional Janus beads by photochemical "sandwich" microcontact printing
Chem Commun (Camb), 49 (1), 63-5
DOI 10.1039/c2cc36483b, PubMed 23165196
Rapid preparation of multifunctional surfaces for orthogonal ligation by microcontact chemistry
Chemistry, 18 (19), 5880-8
DOI 10.1002/chem.201103422, PubMed 22508679
Publications 2011
"Sandwich" microcontact printing as a mild route towards monodisperse Janus particles with tailored bifunctionality
Adv Mater, 23 (1), 79-83
DOI 10.1002/adma.201003564, PubMed 21069890
ARTiiFACT: a tool for heart rate artifact processing and heart rate variability analysis
Behav Res Methods, 43 (4), 1161-70
DOI 10.3758/s13428-011-0107-7, PubMed 21573720
Effects of resting heart rate variability on performance in the P300 brain-computer interface
Int J Psychophysiol, 83 (3), 336-41
DOI 10.1016/j.ijpsycho.2011.11.018, PubMed 22172335
Out of the frying pan into the fire--the P300-based BCI faces real-world challenges
Prog Brain Res, 194, 27-46
DOI 10.1016/B978-0-444-53815-4.00019-4, PubMed 21867792