Publications 2025

Askeland-Gjerde DE, Westlye LT, Andersson P, Korbmacher M, de Lange AM, van der Meer D, Smeland OB, Halvorsen S, Andreassen OA, Gurholt TP (2025)
Mediation Analyses Link Cardiometabolic Factors and Liver Fat With White Matter Hyperintensities and Cognitive Performance: A UK Biobank Study
Biol Psychiatry Glob Open Sci, 5 (4), 100488
DOI 10.1016/j.bpsgos.2025.100488, PubMed 40330223

Publications 2024

Andersson P, Linge J, Gurholt TP, Sønderby IE, Hindley G, Andreassen OA, Dahlqvist Leinhard O (2024)
Poor muscle health and cardiometabolic risks associated with antidepressant treatment
Obesity (Silver Spring), 32 (10), 1857-1869
DOI 10.1002/oby.24085, PubMed 39315407

Beck D, de Lange AG, Gurholt TP, Voldsbekk I, Maximov II, Subramaniapillai S, Schindler L, Hindley G, Leonardsen EH, Rahman Z, van der Meer D, Korbmacher M, Linge J, Leinhard OD, Kalleberg KT, Engvig A, Sønderby I, Andreassen OA, Westlye LT (2024)
Dissecting unique and common variance across body and brain health indicators using age prediction
Hum Brain Mapp, 45 (6), e26685
DOI 10.1002/hbm.26685, PubMed 38647042

Bell C, Rokicki J, Tesli N, Gurholt TP, Hjell G, Fischer-Vieler T, Bang N, Melle I, Agartz I, Andreassen OA, Ringen PA, Rasmussen K, Dahl H, Friestad C, Haukvik UK (2024)
Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-023-01725-4, PubMed 38353675

Chen X, Hu K, Song H, Yin L, Kaijser M, Gurholt TP, Andreassen OA, Valdimarsdóttir U, Fang F, Duan M (2024)
Depression, anxiety and brain volume after hearing loss and tinnitus: cohort study in the UK Biobank
BJPsych Open, 10 (2), e37
DOI 10.1192/bjo.2023.634, PubMed 38297917

Chen X, Wei D, Fang F, Song H, Yin L, Kaijser M, Gurholt TP, Andreassen OA, Valdimarsdóttir U, Hu K, Duan M (2024)
Peripheral vertigo and subsequent risk of depression and anxiety disorders: a prospective cohort study using the UK Biobank
BMC Med, 22 (1), 63
DOI 10.1186/s12916-023-03179-w, PubMed 38336700

Gurholt TP, Borda MG, Parker N, Fominykh V, Kjelkenes R, Linge J, van der Meer D, Sønderby IE, Duque G, Westlye LT, Aarsland D, Andreassen OA (2024)
Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study
Brain Commun, 6 (2), fcae083
DOI 10.1093/braincomms/fcae083, PubMed 38510210

Gurholt TP, Elvsåshagen T, Bahrami S, Rahman Z, Shadrin A, Askeland-Gjerde DE, van der Meer D, Frei O, Kaufmann T, Sønderby IE, Halvorsen S, Westlye LT, Andreassen OA (2024)
Large-scale brainstem neuroimaging and genetic analyses provide new insights into the neuronal mechanisms of hypertension
HGG Adv, 6 (1), 100392
DOI 10.1016/j.xhgg.2024.100392, PubMed 39663699

Publications 2023

Korbmacher M, Gurholt TP, de Lange AG, van der Meer D, Beck D, Eikefjord E, Lundervold A, Andreassen OA, Westlye LT, Maximov II (2023)
Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
Front Psychol, 14, 1117732
DOI 10.3389/fpsyg.2023.1117732, PubMed 37359862

Schindler LS, Subramaniapillai S, Ambikairajah A, Barth C, Crestol A, Voldsbekk I, Beck D, Gurholt TP, Topiwala A, Suri S, Ebmeier KP, Andreassen OA, Draganski B, Westlye LT, de Lange AG (2023)
Cardiometabolic health across menopausal years is linked to white matter hyperintensities up to a decade later
Front Glob Womens Health, 4, 1320640
DOI 10.3389/fgwh.2023.1320640, PubMed 38213741

Publications 2022

Barth C, Kelly S, Nerland S, Jahanshad N, Alloza C, Ambrogi S, Andreassen OA, Andreou D, Arango C, Baeza I, Banaj N, Bearden CE, Berk M, Bohman H, Castro-Fornieles J, Chye Y, Crespo-Facorro B, de la Serna E, Díaz-Caneja CM, Gurholt TP, Hegarty CE, James A, Janssen J, Johannessen C, Jönsson EG et al. (2022)
In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis
Mol Psychiatry, 28 (3), 1159-1169
DOI 10.1038/s41380-022-01901-3, PubMed 36510004

Beck D, de Lange AG, Alnæs D, Maximov II, Pedersen ML, Leinhard OD, Linge J, Simon R, Richard G, Ulrichsen KM, Dørum ES, Kolskår KK, Sanders AM, Winterton A, Gurholt TP, Kaufmann T, Steen NE, Nordvik JE, Andreassen OA, Westlye LT (2022)
Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults
Neuroimage Clin, 33, 102949
DOI 10.1016/j.nicl.2022.102949, PubMed 35114636

Bell C, Tesli N, Gurholt TP, Rokicki J, Hjell G, Fischer-Vieler T, Melle I, Agartz I, Andreassen OA, Ringen PA, Rasmussen K, Dahl H, Friestad C, Haukvik UK (2022)
Psychopathy subdomains in violent offenders with and without a psychotic disorder
Nord J Psychiatry, 77 (4), 393-402
DOI 10.1080/08039488.2022.2128869, PubMed 36260740

Schindler LS, Subramaniapillai S, Barth C, van der Meer D, Pedersen ML, Kaufmann T, Maximov II, Linge J, Leinhard OD, Beck D, Gurholt TP, Voldsbekk I, Suri S, Ebmeier KP, Draganski B, Andreassen OA, Westlye LT, de Lange AG (2022)
Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women
Neuroimage Clin, 36, 103239
DOI 10.1016/j.nicl.2022.103239, PubMed 36451350

Subramaniapillai S, Suri S, Barth C, Maximov II, Voldsbekk I, van der Meer D, Gurholt TP, Beck D, Draganski B, Andreassen OA, Ebmeier KP, Westlye LT, de Lange AG (2022)
Sex- and age-specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort
Hum Brain Mapp, 43 (12), 3759-3774
DOI 10.1002/hbm.25882, PubMed 35460147

van der Meer D, Gurholt TP, Sønderby IE, Shadrin AA, Hindley G, Rahman Z, de Lange AG, Frei O, Leinhard OD, Linge J, Simon R, Beck D, Westlye LT, Halvorsen S, Dale AM, Karlsen TH, Kaufmann T, Andreassen OA (2022)
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
Commun Biol, 5 (1), 1271
DOI 10.1038/s42003-022-04237-4, PubMed 36402844

Winterton A, Bettella F, Beck D, Gurholt TP, Steen NE, Rødevand L, Westlye LT, Andreassen OA, Quintana DS (2022)
The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health
Psychoneuroendocrinology, 144, 105875
DOI 10.1016/j.psyneuen.2022.105875, PubMed 35939863

Publications 2021

Bell C, Tesli N, Gurholt TP, Rokicki J, Hjell G, Fischer-Vieler T, Melle I, Agartz I, Andreassen OA, Rasmussen K, Johansen R, Friestad C, Haukvik UK (2021)
Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending
Psychiatry Res Neuroimaging, 319, 111416
DOI 10.1016/j.pscychresns.2021.111416, PubMed 34847406

Gurholt TP, Kaufmann T, Frei O, Alnæs D, Haukvik UK, van der Meer D, Moberget T, O'Connell KS, Leinhard OD, Linge J, Simon R, Smeland OB, Sønderby IE, Winterton A, Steen NE, Westlye LT, Andreassen OA (2021)
Population-based body-brain mapping links brain morphology with anthropometrics and body composition
Transl Psychiatry, 11 (1), 295
DOI 10.1038/s41398-021-01414-7, PubMed 34006848

Publications 2020

Barth C, Lonning V, Gurholt TP, Andreassen OA, Myhre AM, Agartz I (2020)
Exploring white matter microstructure and the impact of antipsychotics in adolescent-onset psychosis
PLoS One, 15 (5), e0233684
DOI 10.1371/journal.pone.0233684, PubMed 32470000

Ching CRK, Hibar DP, Gurholt TP, Nunes A, Thomopoulos SI, Abé C, Agartz I, Brouwer RM, Cannon DM, de Zwarte SMC, Eyler LT, Favre P, Hajek T, Haukvik UK, Houenou J, Landén M, Lett TA, McDonald C, Nabulsi L, Patel Y, Pauling ME, Paus T, Radua J, Soeiro-de-Souza MG, Tronchin G et al. (2020)
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849

Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR et al. (2020)
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296

Gurholt TP, Haukvik UK, Lonning V, Jönsson EG, Pasternak O, Agartz I (2020)
Microstructural White Matter and Links With Subcortical Structures in Chronic Schizophrenia: A Free-Water Imaging Approach
Front Psychiatry, 11, 56
DOI 10.3389/fpsyt.2020.00056, PubMed 32180735

Gurholt TP, Lonning V, Nerland S, Jørgensen KN, Haukvik UK, Alloza C, Arango C, Barth C, Bearden CE, Berk M, Bohman H, Dandash O, Díaz-Caneja CM, Edbom CT, van Erp TGM, Fett AJ, Frangou S, Goldstein BI, Grigorian A, Jahanshad N, James AC, Janssen J, Johannessen C, Karlsgodt KH, Kempton MJ et al. (2020)
Intracranial and subcortical volumes in adolescents with early-onset psychosis: A multisite mega-analysis from the ENIGMA consortium
Hum Brain Mapp, 43 (1), 373-384
DOI 10.1002/hbm.25212, PubMed 33017498

Haukvik UK, Gurholt TP, Nerland S, Elvsåshagen T, Akudjedu TN, Alda M, Alnaes D, Alonso-Lana S, Bauer J, Baune BT, Benedetti F, Berk M, Bettella F, Bøen E, Bonnín CM, Brambilla P, Canales-Rodríguez EJ, Cannon DM, Caseras X, Dandash O, Dannlowski U, Delvecchio G, Díaz-Zuluaga AM, van Erp TGM, Fatjó-Vilas M et al. (2020)
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925

Thompson PM, Jahanshad N, Ching CRK, Salminen LE, Thomopoulos SI, Bright J, Baune BT, Bertolín S, Bralten J, Bruin WB, Bülow R, Chen J, Chye Y, Dannlowski U, de Kovel CGF, Donohoe G, Eyler LT, Faraone SV, Favre P, Filippi CA, Frodl T, Garijo D, Gil Y, Grabe HJ, Grasby KL et al. (2020)
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Transl Psychiatry, 10 (1), 100
DOI 10.1038/s41398-020-0705-1, PubMed 32198361

Tønnesen S, Kaufmann T, de Lange AG, Richard G, Doan NT, Alnæs D, van der Meer D, Rokicki J, Moberget T, Maximov II, Agartz I, Aminoff SR, Beck D, Barch DM, Beresniewicz J, Cervenka S, Fatouros-Bergman H, Craven AR, Flyckt L, Gurholt TP, Haukvik UK, Hugdahl K, Johnsen E, Jönsson EG, Karolinska Schizophrenia Project et al. (2020)
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 5 (12), 1095-1103
DOI 10.1016/j.bpsc.2020.06.014, PubMed 32859549

Wierenga LM, Doucet GE, Dima D, Agartz I, Aghajani M, Akudjedu TN, Albajes-Eizagirre A, Alnaes D, Alpert KI, Andreassen OA, Anticevic A, Asherson P, Banaschewski T, Bargallo N, Baumeister S, Baur-Streubel R, Bertolino A, Bonvino A, Boomsma DI, Borgwardt S, Bourque J, den Braber A, Brandeis D, Breier A, Brodaty H et al. (2020)
Greater male than female variability in regional brain structure across the lifespan
Hum Brain Mapp, 43 (1), 470-499
DOI 10.1002/hbm.25204, PubMed 33044802

Publications 2019

Schwarz E, Doan NT, Pergola G, Westlye LT, Kaufmann T, Wolfers T, Brecheisen R, Quarto T, Ing AJ, Di Carlo P, Gurholt TP, Harms RL, Noirhomme Q, Moberget T, Agartz I, Andreassen OA, Bellani M, Bertolino A, Blasi G, Brambilla P, Buitelaar JK, Cervenka S, Flyckt L, Frangou S, Franke B et al. (2019)
Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder
Transl Psychiatry, 9 (1), 12
DOI 10.1038/s41398-018-0225-4, PubMed 30664633

Tesli N, Westlye LT, Storvestre GB, Gurholt TP, Agartz I, Melle I, Andreassen OA, Haukvik UK (2019)
White matter microstructure in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 271 (4), 623-634
DOI 10.1007/s00406-019-00988-0, PubMed 30694361

Publications 2018

Berg AO, Jørgensen KN, Nerhus M, Athanasiu L, Popejoy AB, Bettella F, Norbom LCB, Gurholt TP, Dahl SR, Andreassen OA, Djurovic S, Agartz I, Melle I (2018)
Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
DOI 10.1371/journal.pone.0200250, PubMed 30142216

Gurholt TP, Nerhus M, Osnes K, Berg AO, Andreassen OA, Melle I, Agartz I (2018)
Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D
Schizophr Res, 199, 433-435
DOI 10.1016/j.schres.2018.03.011, PubMed 29555212

Gurholt TP, Osnes K, Nerhus M, Jørgensen KN, Lonning V, Berg AO, Andreassen OA, Melle I, Agartz I (2018)
Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls
Sci Rep, 8 (1), 10817
DOI 10.1038/s41598-018-29141-y, PubMed 30018414

Tønnesen S, Kaufmann T, Doan NT, Alnæs D, Córdova-Palomera A, Meer DV, Rokicki J, Moberget T, Gurholt TP, Haukvik UK, Ueland T, Lagerberg TV, Agartz I, Andreassen OA, Westlye LT (2018)
White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging
Sci Rep, 8 (1), 14129
DOI 10.1038/s41598-018-32355-9, PubMed 30237410

van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, Pearlson GD, Yao N, Fukunaga M, Hashimoto R, Okada N, Yamamori H, Bustillo JR, Clark VP, Agartz I, Mueller BA, Cahn W, de Zwarte SMC, Hulshoff Pol HE, Kahn RS, Ophoff RA, van Haren NEM, Andreassen OA, Dale AM, Doan NT et al. (2018)
Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
Biol Psychiatry, 84 (9), 644-654
DOI 10.1016/j.biopsych.2018.04.023, PubMed 29960671

van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, Pearlson GD, Yao N, Fukunaga M, Hashimoto R, Okada N, Yamamori H, Clark VP, Mueller BA, de Zwarte SMC, Ophoff RA, van Haren NEM, Andreassen OA, Gurholt TP, Gruber O, Kraemer B, Richter A, Calhoun VD, Crespo-Facorro B, Roiz-Santiañez R et al. (2018)
Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
Biol Psychiatry, 85 (7), e35-e39
DOI 10.1016/j.biopsych.2018.10.003, PubMed 30470561

Publications 2017

Kelly S, Jahanshad N, Zalesky A, Kochunov P, Agartz I, Alloza C, Andreassen OA, Arango C, Banaj N, Bouix S, Bousman CA, Brouwer RM, Bruggemann J, Bustillo J, Cahn W, Calhoun V, Cannon D, Carr V, Catts S, Chen J, Chen JX, Chen X, Chiapponi C, Cho KK, Ciullo V et al. (2017)
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
Mol Psychiatry, 23 (5), 1261-1269
DOI 10.1038/mp.2017.170, PubMed 29038599

Nerhus M, Berg AO, Simonsen C, Haram M, Haatveit B, Dahl SR, Gurholt TP, Bjella TD, Ueland T, Andreassen OA, Melle I (2017)
Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders
J Clin Psychiatry, 78 (7), e750-e757
DOI 10.4088/JCP.16m10880, PubMed 28493652

Walton E, Hibar DP, van Erp TG, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, Suarez-Pinilla P, Van Haren NE, de Zwarte SM, Kahn RS, Cahn W, Doan NT, Jørgensen KN, Gurholt TP, Agartz I, Andreassen OA, Westlye LT, Melle I, Berg AO, Mørch-Johnsen L, Faerden A, Flyckt L, Fatouros-Bergman H, Karolinska Schizophrenia Project Consortium (KaSP), Jönsson EG et al. (2017)
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium
Acta Psychiatr Scand, 135 (5), 439-447
DOI 10.1111/acps.12718, PubMed 28369804

Walton E, Hibar DP, van Erp TGM, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, Suarez-Pinilla P, van Haren NEM, de Zwarte SMC, Kahn RS, Cahn W, Doan NT, Jørgensen KN, Gurholt TP, Agartz I, Andreassen OA, Westlye LT, Melle I, Berg AO, Morch-Johnsen L, Færden A, Flyckt L, Fatouros-Bergman H, Karolinska Schizophrenia Project Consortium (KaSP), Jönsson EG et al. (2017)
Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium
Psychol Med, 48 (1), 82-94
DOI 10.1017/S0033291717001283, PubMed 28545597

Publications 2009

Gurholt TP, Tai XC (2009)
3D Multiphase Piecewise Constant Level Set Method Based on Graph Cut Minimization
Numer. Math.-Theory Methods Appl., 2 (4), 403-420
DOI 10.4208/nmtma.2009.m9003s