Audun Stubhaug
- Consultant anesthesiologist, Professor; MD
- +47 230 73696
Alternative email address: audun.stubhaug@medisin.uio.no
Publications 2024
Absorption and pharmacokinetics of bupivacaine after bilateral topical administration in tonsillar fossae for posttonsillectomy pain relief
Pharmacol Res Perspect, 12 (2), e1196
DOI 10.1002/prp2.1196, PubMed 38597351
Spinal cord stimulation has a place in the treatment of chronic pain conditions
Tidsskr Nor Laegeforen, 144 (7)
DOI 10.4045/tidsskr.24.0120, PubMed 38832603
Associations of long-term clinical recovery and improved quality of life across ICD-11 chronic pain categories in a real-world registry study
Eur J Pain, 28 (7), 1171-1184
DOI 10.1002/ejp.2250, PubMed 38372480
H-coil repetitive transcranial magnetic stimulation does not improve executive function in patients with chronic peripheral neuropathic pain: a randomized sham-controlled crossover study
Front Psychiatry, 15, 1401008
DOI 10.3389/fpsyt.2024.1401008, PubMed 39086728
The physical activity paradox; exploring the relationship with pain outcomes. The Tromsø Study 2015-2016
Pain (in press)
DOI 10.1097/j.pain.0000000000003344, PubMed 39226083
Periodontitis is associated with decreased experimental pressure pain tolerance: The Tromsø Study 2015-2016
J Clin Periodontol, 51 (7), 874-883
DOI 10.1111/jcpe.13968, PubMed 38426377
Long-term intrathecal infusion of low-dose morphine effectively relieves symptoms of severe restless legs syndrome/Willis-Ekbom disease without inducing opioid tolerance
Pain (in press)
DOI 10.1097/j.pain.0000000000003311, PubMed 39106456
How is age at menopause and reproductive lifespan associated with chronic pain outcomes in postmenopausal women?
Pain (in press)
DOI 10.1097/j.pain.0000000000003333, PubMed 39058956
Associations between cognitive test scores and pain tolerance: The Tromsø study
Scand J Pain, 24 (1)
DOI 10.1515/sjpain-2023-0082, PubMed 38495000
Living well with chronic pain: a 12-month randomized controlled trial revealing impact from the digital pain self-management program EPIO
Pain Rep, 9 (4), e1174
DOI 10.1097/PR9.0000000000001174, PubMed 38962688
The costs of chronic pain-Long-term estimates
Eur J Pain, 28 (6), 960-977
DOI 10.1002/ejp.2234, PubMed 38214661
Does pain tolerance mediate the effect of physical activity on chronic pain in the general population? The Tromsø Study
Pain, 165 (9), 2011-2023
DOI 10.1097/j.pain.0000000000003209, PubMed 38442413
Publications 2023
Short-Term Findings From Testing EPIO, a Digital Self-Management Program for People Living With Chronic Pain: Randomized Controlled Trial
J Med Internet Res, 25, e47284
DOI 10.2196/47284, PubMed 37624622
Comparison of the analgesic effects of "superficial" and "deep" repetitive transcranial magnetic stimulation in patients with central neuropathic pain: a randomized sham-controlled multicenter international crossover study
Pain, 165 (4), 884-892
DOI 10.1097/j.pain.0000000000003082, PubMed 37851075
Economic burden of osteoarthritis - multi-country estimates of direct and indirect costs from the BISCUITS study
Scand J Pain, 23 (4), 694-704
DOI 10.1515/sjpain-2023-0015, PubMed 37381657
Problematic opioid use among osteoarthritis patients with chronic post-operative pain after joint replacement: analyses from the BISCUITS study
Scand J Pain, 23 (2), 353-363
DOI 10.1515/sjpain-2022-0137, PubMed 36799711
Stress specifically deteriorates working memory in peripheral neuropathic pain and fibromyalgia
Brain Commun, 5 (4), fcad194
DOI 10.1093/braincomms/fcad194, PubMed 37465756
Gray matter volume and pain tolerance in a general population: the Tromsø study
Pain, 164 (8), 1750-1758
DOI 10.1097/j.pain.0000000000002871, PubMed 36877481
Pain tolerance after stroke: The Tromsø study
Eur J Pain, 27 (7), 912-921
DOI 10.1002/ejp.2124, PubMed 37167415
Longitudinal relationships between habitual physical activity and pain tolerance in the general population
PLoS One, 18 (5), e0285041
DOI 10.1371/journal.pone.0285041, PubMed 37224163
Publications 2022
Reduced heart rate variability is related to the number of metabolic syndrome components and manifest diabetes in the sixth Tromsø study 2007-2008
Sci Rep, 12 (1), 11998
DOI 10.1038/s41598-022-15824-0, PubMed 35835836
Engaging with EPIO, a digital pain self-management program: a qualitative study
BMC Health Serv Res, 22 (1), 577
DOI 10.1186/s12913-022-07963-x, PubMed 35488295
To tolerate weather and to tolerate pain: two sides of the same coin? The Tromsø Study 7
Pain, 163 (5), 878-886
DOI 10.1097/j.pain.0000000000002437, PubMed 34510136
Consistent pattern between physical activity measures and chronic pain levels: the Tromsø Study 2015 to 2016
Pain, 164 (4), 838-847
DOI 10.1097/j.pain.0000000000002773, PubMed 36083173
Burden of disease and management of osteoarthritis and chronic low back pain: healthcare utilization and sick leave in Sweden, Norway, Finland and Denmark (BISCUITS): study design and patient characteristics of a real world data study
Scand J Pain, 23 (1), 126-138
DOI 10.1515/sjpain-2021-0212, PubMed 35858277
A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain
Scand J Pain, 23 (1), 110-125
DOI 10.1515/sjpain-2021-0197, PubMed 35420264
The association between age at menarche and chronic pain outcomes in women: the Tromsø Study, 2007 to 2016
Pain, 163 (9), 1790-1799
DOI 10.1097/j.pain.0000000000002579, PubMed 35239542
Meditative-based diaphragmatic breathing vs. vagus nerve stimulation in the treatment of fibromyalgia-A randomized controlled trial: Body vs. machine
Front Neurol, 13, 1030927
DOI 10.3389/fneur.2022.1030927, PubMed 36438970
Perceived Injustice in Patients With Chronic Pain: Prevalence, Relevance, and Associations With Long-Term Recovery and Deterioration
J Pain, 23 (7), 1196-1207
DOI 10.1016/j.jpain.2022.01.007, PubMed 35151872
Publications 2021
Possible opioid-saving effect of cannabis-based medicine using individual-based data from the Norwegian Prescription Database
Basic Clin Pharmacol Toxicol, 130 (1), 84-92
DOI 10.1111/bcpt.13660, PubMed 34559439
Low Pain Tolerance Is Associated With Coronary Angiography, Coronary Artery Disease, and Mortality: The Tromsø Study
J Am Heart Assoc, 10 (22), e021291
DOI 10.1161/JAHA.121.021291, PubMed 34729991
Comparing objective cognitive impairments in patients with peripheral neuropathic pain or fibromyalgia
Sci Rep, 11 (1), 673
DOI 10.1038/s41598-020-80740-0, PubMed 33436883
Spinal cord stimulation for the treatment of peripheral neuropathic pain
Tidsskr Nor Laegeforen, 141 (9)
DOI 10.4045/tidsskr.20.1010, PubMed 34107661
[Correction: Spinal cord stimulation for the treatment of peripheral neuropathic pain]
Tidsskr Nor Laegeforen, 141 (10)
DOI 10.4045/tidsskr.21.0453, PubMed 34182742
The indirect impact of heart rate variability on cold pressor pain tolerance and intensity through psychological distress in individuals with chronic pain: the Tromsø Study
Pain Rep, 7 (2), e970
DOI 10.1097/PR9.0000000000000970, PubMed 35187378
The predictive value of quantitative sensory testing: a systematic review on chronic postoperative pain and the analgesic effect of pharmacological therapies in patients with chronic pain
Pain, 162 (1), 31-44
DOI 10.1097/j.pain.0000000000002019, PubMed 32701654
Opioid crisis could be called off
Tidsskr. Nor. Laegeforen., 141 (13), 1248
[Not Available]
Tidsskr Nor Laegeforen, 141 (2021-13)
DOI 10.4045/tidsskr.21.0621, PubMed 34596995
[S. Vambheim and colleagues respond]
Tidsskr Nor Laegeforen, 141 (18)
DOI 10.4045/tidsskr.21.0819, PubMed 34911268
Health care providers' experiences of pain management and attitudes towards digitally supported self-management interventions for chronic pain: a qualitative study
BMC Health Serv Res, 21 (1), 275
DOI 10.1186/s12913-021-06278-7, PubMed 33766028
Publications 2020
Digital Self-Management in Support of Patients Living With Chronic Pain: Feasibility Pilot Study
JMIR Form Res, 4 (10), e23893
DOI 10.2196/23893, PubMed 33094734
A population-based study of inflammatory mechanisms and pain sensitivity
Pain, 161 (2), 338-350
DOI 10.1097/j.pain.0000000000001731, PubMed 31651577
A User-Centered Approach to an Evidence-Based Electronic Health Pain Management Intervention for People With Chronic Pain: Design and Development of EPIO
J Med Internet Res, 22 (1), e15889
DOI 10.2196/15889, PubMed 31961331
Motivational nondirective resonance breathing versus transcutaneous vagus nerve stimulation in the treatment of fibromyalgia: study protocol for a randomized controlled trial
Trials, 21 (1), 808
DOI 10.1186/s13063-020-04703-6, PubMed 32967704
The Graphical Index of Pain: a new web-based method for high-throughput screening of pain
Pain, 161 (10), 2255-2262
DOI 10.1097/j.pain.0000000000001899, PubMed 32345913
Physical activity and cold pain tolerance in the general population
Eur J Pain, 25 (3), 637-650
DOI 10.1002/ejp.1699, PubMed 33165994
Publications 2019
Working in a cold environment, feeling cold at work and chronic pain: a cross-sectional analysis of the Tromsø Study
BMJ Open, 9 (11), e031248
DOI 10.1136/bmjopen-2019-031248, PubMed 31719082
Predicting the outcome of persistent sciatica using conditioned pain modulation: 1-year results from a prospective cohort study
Scand J Pain, 20 (1), 69-75
DOI 10.1515/sjpain-2019-0112, PubMed 31527299
The Oslo University Hospital Pain Registry: development of a digital chronic pain registry and baseline data from 1,712 patients
Scand J Pain, 19 (2), 365-373
DOI 10.1515/sjpain-2017-0160, PubMed 30699072
Reply to Letter to the Editor "Clinical registries are essential tools for ensuring quality and improving outcomes in pain medicine" by Baciarello et al
Scand J Pain, 19 (3), 635
DOI 10.1515/sjpain-2019-2010, PubMed 31031268
Acute neuropathic pain: equivalent or different to chronic neuropathic pain? A call for gathering of scientifically based information on acute neuropathic pain
Pain, 160 (11), 2413-2414
DOI 10.1097/j.pain.0000000000001650, PubMed 31283554
Neuropsychological functions of verbal recall and psychomotor speed significantly affect pain tolerance
Eur J Pain, 23 (9), 1608-1618
DOI 10.1002/ejp.1437, PubMed 31355498
Cognitive Effects of Perioperative Pregabalin: Secondary Exploratory Analysis of a Randomized Placebo-controlled Study
Anesthesiology, 130 (1), 63-71
DOI 10.1097/ALN.0000000000002473, PubMed 30335626
Cognitive Effects of Perioperative Pregabalin: Reply
Anesthesiology, 131 (3), 753-754
DOI 10.1097/ALN.0000000000002872, PubMed 31299657
Implementation Strategies to Enhance the Implementation of eHealth Programs for Patients With Chronic Illnesses: Realist Systematic Review
J Med Internet Res, 21 (9), e14255
DOI 10.2196/14255, PubMed 31573934
Publications 2018
Pilot field testing of the chronic pain classification for ICD-11: the results of ecological coding
BMC Public Health, 18 (1), 1239
DOI 10.1186/s12889-018-6135-9, PubMed 30404594
Diagnosis and treatment of chronic abdominal pain 5 years after Roux-en-Y gastric bypass
Surg Obes Relat Dis, 14 (10), 1544-1551
DOI 10.1016/j.soard.2018.06.004, PubMed 30449511
Chronic pain-related changes in cardiovascular regulation and impact on comorbid hypertension in a general population: the Tromsø study
Pain, 159 (1), 119-127
DOI 10.1097/j.pain.0000000000001070, PubMed 28953193
The peer effect on pain tolerance
Scand J Pain, 18 (3), 467-477
DOI 10.1515/sjpain-2018-0060, PubMed 29794275
Genetic variation in P2RX7 and pain tolerance
Pain, 159 (6), 1064-1073
DOI 10.1097/j.pain.0000000000001188, PubMed 29470314
The Standardised Mensendieck Test as a tool for evaluation of movement quality in patients with nonspecific chronic low back pain
Scand J Pain, 18 (2), 203-210
DOI 10.1515/sjpain-2018-0028, PubMed 29794292
Prevalence, Location, and Characteristics of Chronic Pain in Intensive Care Survivors
Pain Manag Nurs, 19 (4), 366-376
DOI 10.1016/j.pmn.2017.11.005, PubMed 29455923
Health-related quality of life in intensive care survivors: Associations with social support, comorbidity, and pain interference
PLoS One, 13 (6), e0199656
DOI 10.1371/journal.pone.0199656, PubMed 29940026
Response to: The Opioid and Pain intensity Index - a proposal
Acta Anaesthesiol Scand, 63 (1), 135-136
DOI 10.1111/aas.13253, PubMed 30203611
Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery
Acta Anaesthesiol Scand, 62 (6), 829-838
DOI 10.1111/aas.13104, PubMed 29512121
Publications 2017
Endocrinopathies in women during opioid therapy cause loss of androgens, fatigue, listlessness, loss of libido and quality of life: stop prescribing opioids or follow the 2016 Centers for Disease Control and Prevention guidelines?
Pain, 158 (1), 1-3
DOI 10.1097/j.pain.0000000000000745, PubMed 27780180
Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist
Scand J Pain, 16, 158-159
DOI 10.1016/j.sjpain.2017.06.001, PubMed 28850396
A new treatable chronic pain diagnosis? Flank pain caused by entrapment of posterior cutaneous branch of intercostal nerves, lateral ACNES coined LACNES
Scand J Pain, 17, 201-202
DOI 10.1016/j.sjpain.2017.10.006, PubMed 29080490
CNS-mechanisms contribute to chronification of pain
Scand J Pain, 15, 137-139
DOI 10.1016/j.sjpain.2017.03.002, PubMed 28850337
Chronic Abdominal Pain and Symptoms 5 Years After Gastric Bypass for Morbid Obesity
Obes Surg, 27 (6), 1438-1445
DOI 10.1007/s11695-016-2499-z, PubMed 28028658
Intensive care survivor-reported symptoms: a longitudinal study of survivors' symptoms
Nurs Crit Care, 23 (1), 48-54
DOI 10.1111/nicc.12330, PubMed 29243344
A tonic heat test stimulus yields a larger and more reliable conditioned pain modulation effect compared to a phasic heat test stimulus
Pain Rep, 2 (6), e626
DOI 10.1097/PR9.0000000000000626, PubMed 29392240
Pregabalin reduces opioid consumption and hyperalgesia but not pain intensity after laparoscopic donor nephrectomy
Acta Anaesthesiol Scand, 61 (10), 1314-1324
DOI 10.1111/aas.12963, PubMed 28849588
From ketobemidone to morphine or oxycodone
Tidsskr. Nor. Laegeforen., 137 (3), 170
[Not Available]
Tidsskr Nor Laegeforen, 137 (3), 170
DOI 10.4045/tidsskr.17.0045, PubMed 28181747
Pain sensitivity and analgesic use among 10,486 adults: the Tromsø study
BMC Pharmacol Toxicol, 18 (1), 45
DOI 10.1186/s40360-017-0149-2, PubMed 28599683
C-reactive protein and cold-pressor tolerance in the general population: the Tromsø Study
Pain, 158 (7), 1280-1288
DOI 10.1097/j.pain.0000000000000912, PubMed 28420008
Validation of the Norwegian Pain Sensitivity Questionnaire
J Pain Res, 10, 1137-1142
DOI 10.2147/JPR.S129540, PubMed 28553134
Preoperative quantitative sensory testing (QST) predicting postoperative pain: Image or mirage?
Scand J Pain, 15, 91-92
DOI 10.1016/j.sjpain.2017.01.012, PubMed 28850357
Publications 2016
The impact of an educational pain management booklet intervention on postoperative pain control after cardiac surgery
Eur J Cardiovasc Nurs, 16 (1), 18-27
DOI 10.1177/1474515116631680, PubMed 26846145
Pain experiences of men and women after cardiac surgery
J Clin Nurs, 25 (19-20), 3058-68
DOI 10.1111/jocn.13329, PubMed 27301786
Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia
Br J Anaesth, 116 (4), 524-30
DOI 10.1093/bja/aev547, PubMed 26934941
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Nat Genet, 48 (8), 856-66
DOI 10.1038/ng.3598, PubMed 27322543
Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Nat Genet, 48 (10), 1296
DOI 10.1038/ng1016-1296c, PubMed 27681292
Important development: Extended Acute Pain Service for patients at high risk of chronic pain after surgery
Scand J Pain, 12, 58-59
DOI 10.1016/j.sjpain.2016.04.005, PubMed 28850494
Pregabalin Has Analgesic, Ventilatory, and Cognitive Effects in Combination with Remifentanil
Anesthesiology, 124 (1), 141-9
DOI 10.1097/ALN.0000000000000913, PubMed 26528775
[From ketobemidone to morphine or oxycodone]
Tidsskr Nor Laegeforen, 136 (18), 1518-1519
DOI 10.4045/tidsskr.16.0510, PubMed 27731593
Persistent analgesic use and the association with chronic pain and other risk factors in the population-a longitudinal study from the Tromsø Study and the Norwegian Prescription Database
Eur J Clin Pharmacol, 72 (8), 977-85
DOI 10.1007/s00228-016-2056-7, PubMed 27071993
Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite
Pain Res Manag, 2016, 7657329
DOI 10.1155/2016/7657329, PubMed 27445627
Why are some patients with chronic pain from anterior abdominal nerve entrapment syndrome (ACNES) refractory to peripheral treatment with neurectomy?
Scand J Pain, 14, 80-81
DOI 10.1016/j.sjpain.2016.11.019, PubMed 28850439
Advances in understanding and treatment of opioid-induced-bowel-dysfunction, opioid-induced-constipation in particular: Nordic recommendations based on multi-specialist input
Scand J Pain, 11, 163-164
DOI 10.1016/j.sjpain.2016.02.003, PubMed 28850462
Chronic compartment syndrome is an under-recognized cause of leg-pain
Scand J Pain, 12, 53-54
DOI 10.1016/j.sjpain.2016.04.007, PubMed 28850491
A population-based study of quantitative sensory testing in adolescents with and without chronic pain
Pain, 157 (12), 2807-2815
DOI 10.1097/j.pain.0000000000000716, PubMed 27780176
Response to the Letter to the Editor: Experimental Comparison of Parametric Versus Nonparametric Analyses of Data From the Cold Pressor Test
J Pain, 17 (1), 128-9
DOI 10.1016/j.jpain.2015.10.004, PubMed 26721380
Pain Tolerance in Persons With Recognized and Unrecognized Myocardial Infarction: A Population-Based, Cross-Sectional Study
J Am Heart Assoc, 5 (12)
DOI 10.1161/JAHA.116.003846, PubMed 28003255
Publications 2015
Complex Regional Pain Syndrome (CRPS) after viper-bite in a pregnant young woman: Pathophysiology and treatment options
Scand J Pain, 10, 108-110
DOI 10.1016/j.sjpain.2015.11.008, PubMed 28361759
Importance of early diagnosis of complex regional pain syndrome (CRPS-1 and C RPS-2): Delayed diagnosis of CRPS is a major problem
Scand J Pain, 11, 49-51
DOI 10.1016/j.sjpain.2015.11.009, PubMed 28850469
[Interdisciplinary education for better pain treatment]
Tidsskr Nor Laegeforen, 135 (12-13), 1114-5
DOI 10.4045/tidsskr.15.0498, PubMed 26130541
Persistent post-surgical pain and signs of nerve injury: the Tromsø Study
Acta Anaesthesiol Scand, 60 (3), 380-92
DOI 10.1111/aas.12653, PubMed 26537886
Pain and pain tolerance in whiplash-associated disorders: A population-based study
Eur J Pain, 20 (6), 949-58
DOI 10.1002/ejp.819, PubMed 26568528
The effect of tracheotomy on drug consumption in patients with acute aneurysmal subarachnoid hemorrhage: an observational study
BMC Anesthesiol, 15, 47
DOI 10.1186/s12871-015-0029-5, PubMed 25883531
Sleep and pain sensitivity in adults
Pain, 156 (8), 1433-1439
DOI 10.1097/j.pain.0000000000000131, PubMed 25915149
Knee osteoarthritis patients with intact pain modulating systems may have low risk of persistent pain after knee joint replacement
Scand J Pain, 6 (1), 41-42
DOI 10.1016/j.sjpain.2014.11.001, PubMed 29911584
Experimental comparison of parametric versus nonparametric analyses of data from the cold pressor test
J Pain, 16 (6), 537-48
DOI 10.1016/j.jpain.2015.03.001, PubMed 25801300
Publications 2014
Burden of disease is often aggravated by opioid treatment of chronic pain patients: Etiology and prevention
Pain, 155 (12), 2441-2443
DOI 10.1016/j.pain.2014.09.011, PubMed 25234088
Chronic pain and cardiovascular stress responses in a general population: the Tromsø Study
J Behav Med, 37 (6), 1193-201
DOI 10.1007/s10865-014-9568-3, PubMed 24793322
Associations between abdominal pain symptom dimensions and depression among adolescents
Scand J Pain, 5 (3), 184-190
DOI 10.1016/j.sjpain.2014.04.003, PubMed 29913707
Widespread hyperalgesia in adolescents with symptoms of irritable bowel syndrome: results from a large population-based study
J Pain, 15 (9), 898-906
DOI 10.1016/j.jpain.2014.05.007, PubMed 24905280
Recommendations on practice of conditioned pain modulation (CPM) testing
Eur J Pain, 19 (6), 805-6
DOI 10.1002/ejp.605, PubMed 25330039
Publications 2013
Mirror-therapy: An important tool in the management of Complex Regional Pain Syndrome (CRPS)
Scand J Pain, 4 (4), 190-197
DOI 10.1016/j.sjpain.2013.07.019, PubMed 29913641
Statistical pearls: Importance of effect-size, blinding, randomization, publication bias, and the overestimated p-values
Scand J Pain, 4 (4), 217-219
DOI 10.1016/j.sjpain.2013.08.001, PubMed 29913631
[Difficult drug reimbursement system for pain patients]
Tidsskr Nor Laegeforen, 133 (2), 130
DOI 10.4045/tidsskr.12.1430, PubMed 23344584
A new treatment principle for neuropathic pain? Approved oncologic drugs: Epidermal growth factor receptor (EGFR) inhibitors dramatically relieve severe neuropathic pain in a case series
Scand J Pain, 4 (1), 1-2
DOI 10.1016/j.sjpain.2012.11.012, PubMed 29913878
Indirect calorimetry reveals that better monitoring of nutrition therapy in pediatric intensive care is needed
JPEN J Parenter Enteral Nutr, 39 (3), 344-52
DOI 10.1177/0148607113511990, PubMed 24255088
Persistent post-surgical pain and experimental pain sensitivity in the Tromsø study: comorbid pain matters
Pain, 155 (2), 341-348
DOI 10.1016/j.pain.2013.10.013, PubMed 24145207
Improvement in Psoriasis Area and Severity Index score predicts improvement in skin pain over time in patients with psoriasis
Acta Derm Venereol, 93 (3), 330-4
DOI 10.2340/00015555-1456, PubMed 23007130
Gender differences in blood pressure-related hypoalgesia in a general population: the Tromsø Study
J Pain, 14 (7), 699-708
DOI 10.1016/j.jpain.2013.01.780, PubMed 23809360
Changes in blood pressure and cardiac output during cesarean delivery: the effects of oxytocin and carbetocin compared with placebo
Anesthesiology, 119 (3), 541-51
DOI 10.1097/ALN.0b013e31829416dd, PubMed 23598289
Conditioned pain modulation: A useful test paradigm in research and in clinical practice
Scand J Pain, 4 (2), 101-102
DOI 10.1016/j.sjpain.2013.02.003, PubMed 29913891
Publications 2012
Pressure-derived versus pressure wave amplitude-derived indices of cerebrovascular pressure reactivity in relation to early clinical state and 12-month outcome following aneurysmal subarachnoid hemorrhage
J Neurosurg, 116 (5), 961-71
DOI 10.3171/2012.1.JNS111313, PubMed 22324419
Persistent pain after surgery for cutaneous melanoma
Clin J Pain, 28 (2), 149-56
DOI 10.1097/AJP.0b013e31822a6887, PubMed 21904198
Persistent postsurgical pain in a general population: prevalence and predictors in the Tromsø study
Pain, 153 (7), 1390-1396
DOI 10.1016/j.pain.2012.02.018, PubMed 22445291
Hypertension prevalence and diminished blood pressure-related hypoalgesia in individuals reporting chronic pain in a general population: the Tromsø study
Pain, 154 (2), 257-262
DOI 10.1016/j.pain.2012.10.020, PubMed 23245863
Increased pain sensitivity among adults reporting irritable bowel syndrome symptoms in a large population-based study
Pain, 154 (3), 385-392
DOI 10.1016/j.pain.2012.11.012, PubMed 23320954
Pressure pain algometry - A call for standardisation of methods
Scand J Pain, 3 (1), 30
DOI 10.1016/j.sjpain.2011.11.010, PubMed 29913763
Can we measure the relative contributions of peripheral and central mechanisms of painful conditions, and how can it guide therapy?
Scand J Pain, 3 (4), 229
DOI 10.1016/j.sjpain.2012.09.005, PubMed 29913867
The incidence of delirium in Norwegian intensive care units; deep sedation makes assessment difficult
Acta Anaesthesiol Scand, 57 (3), 294-302
DOI 10.1111/j.1399-6576.2012.02793.x, PubMed 23075027
Publications 2011
A randomized and blinded single-center trial comparing the effect of intracranial pressure and intracranial pressure wave amplitude-guided intensive care management on early clinical state and 12-month outcome in patients with aneurysmal subarachnoid hemorrhage
Neurosurgery, 69 (5), 1105-15
DOI 10.1227/NEU.0b013e318227e0e1, PubMed 21670714
Paratracheal placement of orotracheal tube: a complication when aborting percutaneous tracheotomy
Acta Anaesthesiol Scand, 55 (7), 897-8
DOI 10.1111/j.1399-6576.2011.02438.x, PubMed 21749335
[Postoperative pain in patients admitted to Norwegian hospitals]
Tidsskr Nor Laegeforen, 131 (18), 1763-7
DOI 10.4045/tidsskr.10.1129, PubMed 21946593
Mental and somatic co-morbidities in chronic orofacial pain conditions: Pain patients in need of multiprofessional team approach
Scand J Pain, 2 (4), 153-154
DOI 10.1016/j.sjpain.2011.08.003, PubMed 29913752
Haemodynamic effects of oxytocin in women with severe preeclampsia
Int J Obstet Anesth, 20 (1), 26-9
DOI 10.1016/j.ijoa.2010.10.004, PubMed 21224021
Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans
Pain, 152 (6), 1289-1297
DOI 10.1016/j.pain.2011.02.007, PubMed 21396775
Skin pain and skin discomfort is associated with quality of life in patients with psoriasis
J Eur Acad Dermatol Venereol, 26 (1), 29-35
DOI 10.1111/j.1468-3083.2011.04000.x, PubMed 21385220
Dexamethasone has additive effect when combined with ondansetron and droperidol for treatment of established PONV
Acta Anaesthesiol Scand, 55 (10), 1196-205
DOI 10.1111/j.1399-6576.2011.02536.x, PubMed 22092124
Percutaneous dilatational tracheotomy in intensive care unit patients with increased bleeding risk or obesity. A prospective analysis of 1000 procedures
Acta Anaesthesiol Scand, 55 (7), 835-41
DOI 10.1111/j.1399-6576.2011.02458.x, PubMed 21615346
Redheads, pain mechanisms and genetics: Lessons learned from inconclusive studies
Scand J Pain, 2 (1), 1-2
DOI 10.1016/j.sjpain.2010.12.003, PubMed 29914001
Analgesia and sedation of mechanically ventilated patients - a national survey of clinical practice
Acta Anaesthesiol Scand, 56 (1), 23-9
DOI 10.1111/j.1399-6576.2011.02524.x, PubMed 22092294
Publications 2010
Why we publish negative studies - and prescriptions on how to do clinical pain trials well
Scand J Pain, 1 (2), 98-99
DOI 10.1016/j.sjpain.2010.01.009, PubMed 29913938
Hyperesthesia one year after breast augmentation surgery increases the odds for persisting pain at four years A prospective four-year follow-up study
Scand J Pain, 1 (2), 75-81
DOI 10.1016/j.sjpain.2010.01.010, PubMed 29913948
Skin pain and discomfort in psoriasis: an exploratory study of symptom prevalence and characteristics
Acta Derm Venereol, 90 (1), 39-45
DOI 10.2340/00015555-0764, PubMed 20107724
Publications 2009
Impedance-based tissue discrimination for needle guidance
Physiol Meas, 30 (2), 129-40
DOI 10.1088/0967-3334/30/2/002, PubMed 19136732
A randomized double-blind controlled trial of intra-annular radiofrequency thermal disc therapy--a 12-month follow-up
Pain, 145 (3), 279-286
DOI 10.1016/j.pain.2009.05.001, PubMed 19647940
Placebo control--still the most ethical study design
Pain, 148 (1), 174-175
DOI 10.1016/j.pain.2009.11.013, PubMed 19962241
Haemodynamic effects of repeated doses of oxytocin during Caesarean delivery in healthy parturients
Br J Anaesth, 103 (2), 260-2
DOI 10.1093/bja/aep137, PubMed 19502285
Low-dose versus a Higher-dose Bupivacaine Spinal Anesthesia for Cesarean Delivery Reply
Anesthesiology, 111 (1), 213-215
DOI 10.1097/ALN.0b013e3181a977e8
Current threshold for nerve stimulation depends on electrical impedance of the tissue: a study of ultrasound-guided electrical nerve stimulation of the median nerve
Anesth Analg, 108 (4), 1338-43
DOI 10.1213/ane.0b013e3181957d84, PubMed 19299809
Publications 2008
Differential effects of osmotherapy on static and pulsatile intracranial pressure
Crit Care Med, 36 (8), 2414-9
DOI 10.1097/CCM.0b013e318180fe04, PubMed 18596629
Assessment of pain
Br J Anaesth, 101 (1), 17-24
DOI 10.1093/bja/aen103, PubMed 18487245
Management of acute postoperative pain: still a long way to go!
Pain, 137 (2), 233-234
DOI 10.1016/j.pain.2008.04.014, PubMed 18479824
Gabapentin in traumatic nerve injury pain: a randomized, double-blind, placebo-controlled, cross-over, multi-center study
Pain, 138 (2), 255-266
DOI 10.1016/j.pain.2007.12.011, PubMed 18258368
Early treatment of tetanus-induced trismus with botulinum toxin A
Anesth Analg, 106 (5), 1591
DOI 10.1213/ANE.0b013e31816a30f0, PubMed 18420892
Continuous invasive blood pressure and cardiac output monitoring during cesarean delivery: a randomized, double-blind comparison of low-dose versus high-dose spinal anesthesia with intravenous phenylephrine or placebo infusion
Anesthesiology, 109 (5), 856-63
DOI 10.1097/ALN.0b013e31818a401f, PubMed 18946298
Understanding international differences in terminology for delirium and other types of acute brain dysfunction in critically ill patients
Intensive Care Med, 34 (10), 1907-15
DOI 10.1007/s00134-008-1177-6, PubMed 18563387
Pain and disability 1 year after knee arthroscopic procedures
Acta Anaesthesiol Scand, 52 (3), 332-7
DOI 10.1111/j.1399-6576.2007.01541.x, PubMed 18269385
Kjønnsforskjeller og smerte
In Ulike tekster om smerte: fra nocisepsjon til livskvalitet, Gyldendal akademisk, Oslo, s. 128-138
BIBSYS 082788294
Pain and quality of life in hospitalized patients with heart failure
J Pain Symptom Manage, 36 (5), 497-504
DOI 10.1016/j.jpainsymman.2007.11.014, PubMed 18619766
Kreft og smerter
In Ulike tekster om smerte: fra nocisepsjon til livskvalitet, Gyldendal akademisk, Oslo, s.255-270
BIBSYS 082788685
Electrical nerve stimulation or ultrasound guidance for lateral sagittal infraclavicular blocks: a randomized, controlled, observer-blinded, comparative study
Anesth Analg, 106 (6), 1910-5
DOI 10.1213/ane.0b013e318173280f, PubMed 18499631
Surgical treatment of aneurysmal subarachnoid haemorrhage in the presence of 24-h endovascular availability: management and results
Br J Neurosurg, 22 (1), 53-62
DOI 10.1080/02688690701593553, PubMed 17852110
Hva er smerte ?
In Ulike tekster om smerte: fra nocisepsjon til livskvalitet, Gyldendal akademisk, Oslo, s. 22-50
BIBSYS 082788197
Publications 2007
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage
Acta Anaesthesiol Scand, 51 (9), 1273-6
DOI 10.1111/j.1399-6576.2007.01433.x, PubMed 17714572
From intracranial pressure to intracranial pressure wave-guided intensive care management of a patient with an aneurysmal subarachnoid haemorrhage
Acta Anaesthesiol Scand, 51 (4), 501-4
DOI 10.1111/j.1399-6576.2007.01269.x, PubMed 17378790
Individual differences in pain sensitivity: genetic and environmental contributions
Pain, 136 (1-2), 21-9
DOI 10.1016/j.pain.2007.06.008, PubMed 17692462
Glucocorticoids for acute and persistent postoperative neuropathic pain: what is the evidence?
Anesthesiology, 107 (3), 371-3
DOI 10.1097/01.anes.0000279487.27940.5c, PubMed 17721239
Synovial fluid concentration of prostaglandin E2 correlates with pain intensity after knee arthroscopic procedures
Anesth Analg, 104 (2), 460-1
DOI 10.1213/01.ane.0000253160.08211.a3, PubMed 17242120
Intra-articular morphine in acute pain trials
Reg Anesth Pain Med, 32 (2), 176-7
DOI 10.1016/j.rapm.2006.12.004, PubMed 17350539
Ultrasound controlled nerve stimulation in the elbow region: high currents and short distances needed to obtain motor responses
Acta Anaesthesiol Scand, 51 (7), 942-8
DOI 10.1111/j.1399-6576.2007.01349.x, PubMed 17578459
Methylprednisolone and ketorolac rapidly reduce hyperalgesia around a skin burn injury and increase pressure pain thresholds
Acta Anaesthesiol Scand, 51 (9), 1138-46
DOI 10.1111/j.1399-6576.2007.01415.x, PubMed 17714578
Publications 2006
Hypertonic saline (7.2%) in 6% hydroxyethyl starch reduces intracranial pressure and improves hemodynamics in a placebo-controlled study involving stable patients with subarachnoid hemorrhage
Crit Care Med, 34 (12), 2912-7
DOI 10.1097/01.CCM.0000245665.46789.7C, PubMed 17075367
Comparison of intracranial pressure measured simultaneously within the brain parenchyma and cerebral ventricles
J Clin Monit Comput, 20 (6), 411-4
DOI 10.1007/s10877-006-9047-7, PubMed 17016744
Hemodynamic effects of oxytocin during cesarean delivery
Int J Gynaecol Obstet, 95 (1), 46-7
DOI 10.1016/j.ijgo.2006.05.032, PubMed 16920118
Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: a single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo
Anesth Analg, 102 (2), 418-25
DOI 10.1213/01.ane.0000194358.46119.e1, PubMed 16428536
Chronic pain and sensory changes after augmentation mammoplasty: long term effects of preincisional administration of methylprednisolone
Pain, 124 (1-2), 92-9
DOI 10.1016/j.pain.2006.03.020, PubMed 16650580
Adding propacetamol to ketorolac increases the tolerance to painful pressure
Eur J Pain, 10 (3), 177-83
DOI 10.1016/j.ejpain.2005.03.003, PubMed 16490726
Smerter
In Teoretisk-metodisk grunnlag for klinisk sykepleie, 2, S.199-242
BIBSYS 071182373
Use of magnetic resonance imaging to define the anatomical location closest to all three cords of the infraclavicular brachial plexus
Anesth Analg, 103 (6), 1574-6
DOI 10.1213/01.ane.0000242529.96675.fd, PubMed 17122242
Intra-articular morphine 5 mg after knee arthroscopy does not produce significant pain relief when administered to patients with moderate to severe pain via an intra-articular catheter
Reg Anesth Pain Med, 31 (6), 506-13
DOI 10.1016/j.rapm.2006.06.206, PubMed 17138192
Publications 2005
Characterizing individual differences in heat-pain sensitivity
Pain, 119 (1-3), 65-74
DOI 10.1016/j.pain.2005.09.018, PubMed 16298065
[Glucocorticoids reduce acute postoperative pain]
Tidsskr Nor Laegeforen, 125 (18), 2507-8
PubMed 16186874
Can opioids prevent post-operative chronic pain?
Eur J Pain, 9 (2), 153-6
DOI 10.1016/j.ejpain.2004.07.008, PubMed 15737806
Publications 2004
Predictable reduction of intracranial hypertension with hypertonic saline hydroxyethyl starch: a prospective clinical trial in critically ill patients with subarachnoid haemorrhage
Acta Anaesthesiol Scand, 48 (9), 1089-95
DOI 10.1111/j.1399-6576.2004.00497.x, PubMed 15352953
Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effects
Acta Anaesthesiol Scand, 48 (10), 1223-31
DOI 10.1111/j.1399-6576.2004.00480.x, PubMed 15504180
Moderate-to-severe pain after knee arthroscopy is relieved by intraarticular saline: a randomized controlled trial
Anesth Analg, 98 (6), 1546-1551
DOI 10.1213/01.ANE.0000112433.71197.FA, PubMed 15155303
Gender is a confounding factor in pain trials: women report more pain than men after arthroscopic surgery
Pain, 112 (3), 248-253
DOI 10.1016/j.pain.2004.08.028, PubMed 15561379
The life of Niels Henrik Abel
LEGACY OF NIELS HENRIK ABEL, 7-20
Publications 2003
Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine--a double-blind, cross-over comparison with alfentanil and placebo
Pain, 101 (3), 229-235
DOI 10.1016/S0304-3959(02)00122-7, PubMed 12583865
Medical end-of-life decisions in Norway
Resuscitation, 57 (3), 311-2; author reply 312-3
DOI 10.1016/s0300-9572(03)00120-5, PubMed 12804809
Effective pain relief from intra-articular saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy: a randomized, double-blind controlled clinical study
Acta Anaesthesiol Scand, 47 (6), 732-8
DOI 10.1034/j.1399-6576.2003.00155.x, PubMed 12803592
Intra-articular (IA) catheter administration of postoperative analgesics. A new trial design allows evaluation of baseline pain, demonstrates large variation in need of analgesics, and finds no analgesic effect of IA ketamine compared with IA saline
Pain, 104 (1-2), 25-34
DOI 10.1016/s0304-3959(02)00463-3, PubMed 12855311
Publications 2002
Cardiac arrest after intravenous metoclopramide - a case of five repeated injections of metoclopramide causing five episodes of cardiac arrest
Acta Anaesthesiol Scand, 46 (7), 908-10
DOI 10.1034/j.1399-6576.2002.460725.x, PubMed 12139551
Detecting postoperative urinary retention with an ultrasound scanner
Acta Anaesthesiol Scand, 46 (3), 279-82
DOI 10.1034/j.1399-6576.2002.t01-1-460309.x, PubMed 11939918
[Postoperative urinary retention]
Tidsskr Nor Laegeforen, 122 (9), 902-4
PubMed 12082832
[A throat infection with rapid deterioration]
Tidsskr Nor Laegeforen, 122 (19), 1896-9
PubMed 12362714
Publications 2000
Preinjury treatment with morphine or ketamine inhibits the development of experimentally induced secondary hyperalgesia in man
Pain, 86 (3), 293-303
DOI 10.1016/S0304-3959(00)00260-8, PubMed 10812259
Publications 1999
Some problems with wind-up and its calculation - Reply
Pain, 83 (1), 111-112
DOI 10.1097/00006396-199910010-00016
Intra-articular morphine for pain relief after knee arthroscopy
Acta Anaesthesiol Scand, 43 (3), 252-7
DOI 10.1034/j.1399-6576.1999.430303.x, PubMed 10081529
Ketamine in the treatment of spontaneous ongoing pain andevoked pain: studies in humans with chronic neuropathic pain, acute postoperative pain, or experimental pain
Department of Anaesthesiology, Rikshospitalet, Universityof Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 991541693, ISBN 82-7722-115-0
Publications 1998
The effect of peripheral glycerol on trigeminal neuropathic pain examined by quantitative assessment of abnormal pain and sensory perception
Acta Neurochir (Wien), 140 (12), 1271-7
DOI 10.1007/s007010050249, PubMed 9932128
Relief of trigeminal neuralgia after percutaneous retrogasserian glycerol rhizolysis is dependent on normalization of abnormal temporal summation of pain, without general impairment of sensory perception
Neurosurgery, 43 (3), 462-72; discussion 472-4
DOI 10.1097/00006123-199809000-00036, PubMed 9733301
Publications 1997
Relief of glossopharyngeal neuralgia by ketamine-induced N-methyl-aspartate receptor blockade
Neurosurgery, 41 (2), 505-8
DOI 10.1097/00006123-199708000-00043, PubMed 9257324
Sensory perception in patients with trigeminal neuralgia: effects of percutaneous retrogasserian glycerol rhizotomy
Stereotact Funct Neurosurg, 68 (1-4 Pt 1), 207-11
DOI 10.1159/000099925, PubMed 9711718
Reply to S.T. Meller: Ketamine: relief from chronic pain through actions at the NMDA receptor
Pain, 72 (1-2), 289-91
DOI 10.1016/s0304-3959(96)03263-0, PubMed 9272819
Ketamine: relief from chronic pain through actions at the NMDA receptor - Reply
Pain, 72 (1-2), 289-291
DOI 10.1097/00006396-199708000-00042
A new method to evaluate central sensitization to pain following surgery. Effect of ketamine
Acta Anaesthesiol Scand Suppl, 110, 154-5
DOI 10.1111/j.1399-6576.1997.tb05540.x, PubMed 9248571
Long-term treatment of chronic neuropathic pain with the NMDA (N-methyl-D-aspartate) receptor antagonist ketamine
Acta Anaesthesiol Scand, 41 (3), 329-31
DOI 10.1111/j.1399-6576.1997.tb04693.x, PubMed 9113174
Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery
Acta Anaesthesiol Scand, 41 (9), 1124-32
DOI 10.1111/j.1399-6576.1997.tb04854.x, PubMed 9366932
Ketamine reduces postoperative hyperalgesia
PROG PAIN RES MANAG, 8, 333-342
Local treatment with the N-methyl-D-aspartate receptor antagonist ketamine, inhibit development of secondary hyperalgesia in man by a peripheral action
Neurosci Lett, 227 (1), 1-4
DOI 10.1016/s0304-3940(97)00263-2, PubMed 9178844
Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo
Pain, 72 (1-2), 99-106
DOI 10.1016/s0304-3959(97)00006-7, PubMed 9272793
Publications 1996
Additive analgesic effect of codeine and paracetamol can be detected in strong, but not moderate, pain after Caesarean section. Baseline pain-intensity is a determinant of assay-sensitivity in a postoperative analgesic trial
Acta Anaesthesiol Scand, 40 (4), 399-407
DOI 10.1111/j.1399-6576.1996.tb04460.x, PubMed 8738682
Comparison of tramadol with morphine for post-operative pain following abdominal surgery
Eur J Anaesthesiol, 13 (4), 416-8
DOI 10.1097/00003643-199607000-00022, PubMed 8842669
Reply to P.E. Vielvoye-kerkmeer
Pain, 64 (2), 402
DOI 10.1016/0304-3959(96)90043-3
Publications 1995
THE NMDA-ANTAGONIST KETAMINE FOR PREVENTION AND TREATMENT OF ACUTE AND CHRONIC POSTOPERATIVE PAIN
Baillieres Clin. Anaesthesiol., 9 (3), 539-554
DOI 10.1016/S0950-3501(95)80021-2
Central dysesthesia pain after traumatic spinal cord injury is dependent on N-methyl-D-aspartate receptor activation
Neurosurgery, 37 (6), 1080-7
DOI 10.1227/00006123-199512000-00007, PubMed 8584148
Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia
Pain, 61 (2), 221-228
DOI 10.1016/0304-3959(94)00182-E, PubMed 7659432
POSTOPERATIVE ANALGESIC TRIALS - SOME IMPORTANT ISSUES
Baillieres Clin. Anaesthesiol., 9 (3), 555-584
DOI 10.1016/S0950-3501(95)80022-0
Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison
Pain, 62 (1), 111-118
DOI 10.1016/0304-3959(95)00056-X, PubMed 7478700
Publications 1994
Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo
Pain, 58 (3), 347-354
DOI 10.1016/0304-3959(94)90129-5, PubMed 7838584
Publications 1992
Ibuprofen plus codeine, ibuprofen, and placebo in a single- and multidose cross-over comparison for coxarthrosis pain
Pain, 50 (3), 303-307
DOI 10.1016/0304-3959(92)90035-A, PubMed 1280802