Publications 2023

Tønnessen TC, Ueland T, Ahmed MS, Attramadal H, Sjaastad I, Vinge LE (2023)
Inflammatory augmentation of the delayed type hypersensitivity arthritis mouse model
Basic Clin Pharmacol Toxicol, 132 (6), 551-555
DOI 10.1111/bcpt.13864, PubMed 36946742

Publications 2022

Tønnessen TC, Melleby AO, Hauge-Iversen IM, Espe EKS, Ahmed MS, Ueland T, Haavardsholm EA, Atkinson SM, Melum E, Attramadal H, Sjaastad I, Vinge LE (2022)
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
PLoS One, 17 (1), e0262821
DOI 10.1371/journal.pone.0262821, PubMed 35077491

Publications 2020

Arain F, Abraityte A, Bogdanova M, Solberg OG, Michelsen AE, Lekva T, Aakhus S, Holm S, Halvorsen B, Finsen AV, Vinge LE, Nymo S, Espeland T, Ranheim T, Aukrust P, Vaage IJ, Auensen A, Gullestad L, Ueland T (2020)
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417

Hamre CFB, Kvammen EMH, Vinge LE, Skeie AT, Hompland I (2020)
[Cardiac sarcoma]
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.19.0455, PubMed 32321220

Hamre CFB, Kvammen EMH, Vinge LE, Skeie AT, Hompland I (2020)
Sarcoma of the heart
Tidsskr. Nor. Laegeforen., 140 (6), 582-583

Publications 2019

Berge T, Bull-Hansen B, Solberg EE, Heyerdahl ER, Jørgensen KN, Vinge LE, Aarønæs M, Øie E, Hyldmo I (2019)
Screening for symptoms of depression and anxiety in a cardiology department
Tidsskr Nor Laegeforen, 139 (14)
DOI 10.4045/tidsskr.18.0570, PubMed 31592606

Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE, Øie E, Gullestad L, Halvorsen B, Hansen TV, Aukrust P, Dalli J, Yndestad A (2019)
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
EBioMedicine, 46, 264-273
DOI 10.1016/j.ebiom.2019.07.024, PubMed 31345784

Torp MK, Yang K, Ranheim T, Husø Lauritzen K, Alfsnes K, Vinge LE, Aukrust P, Stensløkken KO, Yndestad A, Sandanger Ø (2019)
Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts
Front Immunol, 10, 1285
DOI 10.3389/fimmu.2019.01285, PubMed 31244838

Publications 2017

Abraityte A, Vinge LE, Askevold ET, Lekva T, Michelsen AE, Ranheim T, Alfsnes K, Fiane A, Aakhus S, Lunde IG, Dahl CP, Aukrust P, Christensen G, Gullestad L, Yndestad A, Ueland T (2017)
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477

Dhondup Y, Sjaastad I, Sandanger Ø, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang L, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262

Publications 2016

Dhondup Y, Ueland T, Dahl CP, Askevold ET, Sandanger Ø, Fiane A, Ohm IK, Sjaastad I, Finsen AV, Wæhre A, Gullestad L, Aukrust P, Yndestad A, Vinge LE (2016)
Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure
J Card Fail, 22 (10), 823-8
DOI 10.1016/j.cardfail.2016.06.013, PubMed 27349571

Sokolova M, Vinge LE, Alfsnes K, Olsen MB, Eide L, Kaasbøll OJ, Attramadal H, Torp MK, Fosshaug LE, Rashidi A, Lien E, Finsen AV, Sandanger Ø, Aukrust P, Ranheim T, Yndestad A (2016)
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Biochim Biophys Acta Mol Cell Biol Lipids, 1862 (2), 234-245
DOI 10.1016/j.bbalip.2016.11.003, PubMed 27845246

Publications 2015

Dhondup Y, Sjaastad I, Scott H, Sandanger Ø, Zhang L, Haugstad SB, Aronsen JM, Ranheim T, Holmen SD, Alfsnes K, Ahmed MS, Attramadal H, Gullestad L, Aukrust P, Christensen G, Yndestad A, Vinge LE (2015)
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715, PubMed 26461521

Fosshaug LE, Dahl CP, Risnes I, Bohov P, Berge RK, Nymo S, Geiran O, Yndestad A, Gullestad L, Aukrust P, Vinge LE, Øie E (2015)
Altered Levels of Fatty Acids and Inflammatory and Metabolic Mediators in Epicardial Adipose Tissue in Patients With Systolic Heart Failure
J Card Fail, 21 (11), 916-23
DOI 10.1016/j.cardfail.2015.07.014, PubMed 26231517

Sandanger Ø, Gao E, Ranheim T, Bliksøen M, Kaasbøll OJ, Alfsnes K, Nymo SH, Rashidi A, Ohm IK, Attramadal H, Aukrust P, Vinge LE, Yndestad A (2015)
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective
Biochem Biophys Res Commun, 469 (4), 1012-20
DOI 10.1016/j.bbrc.2015.12.051, PubMed 26706279

Publications 2014

Askevold ET, Aukrust P, Nymo SH, Lunde IG, Kaasbøll OJ, Aakhus S, Florholmen G, Ohm IK, Strand ME, Attramadal H, Fiane A, Dahl CP, Finsen AV, Vinge LE, Christensen G, Yndestad A, Gullestad L, Latini R, Masson S, Tavazzi L, GISSI-HF Investigators, Ueland T (2014)
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J Intern Med, 275 (6), 621-30
DOI 10.1111/joim.12175, PubMed 24330105

Ohm IK, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger Ø, Dahl TB, Aukrust P, Finsen AV, Yndestad A, Vinge LE (2014)
Toll-like receptor 9 mediated responses in cardiac fibroblasts
PLoS One, 9 (8), e104398
DOI 10.1371/journal.pone.0104398, PubMed 25126740

Ohm IK, Gao E, Belland Olsen M, Alfsnes K, Bliksøen M, Øgaard J, Ranheim T, Nymo SH, Holmen YD, Aukrust P, Yndestad A, Vinge LE (2014)
Toll-like receptor 9-activation during onset of myocardial ischemia does not influence infarct extension
PLoS One, 9 (8), e104407
DOI 10.1371/journal.pone.0104407, PubMed 25126943

Publications 2013

Kaikkonen L, Magga J, Ronkainen VP, Koivisto E, Perjes Á, Chuprun JK, Vinge LE, Kilpiö T, Aro J, Ulvila J, Alakoski T, Bibb JA, Szokodi I, Koch WJ, Ruskoaho H, Kerkelä R (2013)
p38α regulates SERCA2a function
J Mol Cell Cardiol, 67, 86-93
DOI 10.1016/j.yjmcc.2013.12.005, PubMed 24361238

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A (2013)
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury
Cardiovasc Res, 99 (1), 164-74
DOI 10.1093/cvr/cvt091, PubMed 23580606

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Valen G, Aukrust P, Yndestad A (2013)
A role for NLRP3 inflammasome in acute myocardial ischaemia-reperfusion injury? Reply
Cardiovasc Res, 99 (1), 226-7
DOI 10.1093/cvr/cvt130, PubMed 23708737

Publications 2012

Bliksøen M, Mariero LH, Ohm IK, Haugen F, Yndestad A, Solheim S, Seljeflot I, Ranheim T, Andersen GØ, Aukrust P, Valen G, Vinge LE (2012)
Increased circulating mitochondrial DNA after myocardial infarction
Int J Cardiol, 158 (1), 132-4
DOI 10.1016/j.ijcard.2012.04.047, PubMed 22578950

Gullestad L, Ueland T, Vinge LE, Finsen A, Yndestad A, Aukrust P (2012)
Inflammatory cytokines in heart failure: mediators and markers
Cardiology, 122 (1), 23-35
DOI 10.1159/000338166, PubMed 22699305

Raake PW, Zhang X, Vinge LE, Brinks H, Gao E, Jaleel N, Li Y, Tang M, Most P, Dorn GW, Houser SR, Katus HA, Chen X, Koch WJ (2012)
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction
Circulation, 125 (17), 2108-18
DOI 10.1161/CIRCULATIONAHA.111.044255, PubMed 22496128

von Lueder TG, Gravning J, How OJ, Vinge LE, Ahmed MS, Krobert KA, Levy FO, Larsen TS, Smiseth OA, Aasum E, Attramadal H (2012)
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
Am J Physiol Heart Circ Physiol, 303 (1), H66-74
DOI 10.1152/ajpheart.00724.2011, PubMed 22542621

Waehre A, Vistnes M, Sjaastad I, Nygård S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433

Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P (2012)
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
DOI 10.1371/journal.pone.0033038, PubMed 22427939

Publications 2011

Fosshaug LE, Berge RK, Beitnes JO, Berge K, Vik H, Aukrust P, Gullestad L, Vinge LE, Øie E (2011)
Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
Lipids Health Dis, 10, 245
DOI 10.1186/1476-511X-10-245, PubMed 22206454

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157

Publications 2010

Ahmed MS, Gravning J, Martinov VN, von Lueder TG, Edvardsen T, Czibik G, Moe IT, Vinge LE, Øie E, Valen G, Attramadal H (2010)
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol, 300 (4), H1291-302
DOI 10.1152/ajpheart.00604.2010, PubMed 21186275

Aukrust P, Sandberg WJ, Otterdal K, Vinge LE, Gullestad L, Yndestad A, Halvorsen B, Ueland T (2010)
Tumor necrosis factor superfamily molecules in acute coronary syndromes
Ann Med, 43 (2), 90-103
DOI 10.3109/07853890.2010.523711, PubMed 21039303

Øie E, Ahmed MS, Ueland T, Sikkeland LI, Dahl CP, Hagelin EM, von Lueder T, Edvardsen T, Andreassen AK, Gullestad L, Aukrust P, Yndestad A, Vinge LE, Attramadal H (2010)
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res Cardiol, 105 (1), 89-98
DOI 10.1007/s00395-009-0070-y, PubMed 19823891

Publications 2009

Dahl CP, Husberg C, Gullestad L, Waehre A, Damås JK, Vinge LE, Finsen AV, Ueland T, Florholmen G, Aakhus S, Halvorsen B, Aukrust P, Oie E, Yndestad A, Christensen G (2009)
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
DOI 10.1161/CIRCHEARTFAILURE.108.821074, PubMed 19919988

Yndestad A, Landrø L, Ueland T, Dahl CP, Flo TH, Vinge LE, Espevik T, Frøland SS, Husberg C, Christensen G, Dickstein K, Kjekshus J, Øie E, Gullestad L, Aukrust P (2009)
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur Heart J, 30 (10), 1229-36
DOI 10.1093/eurheartj/ehp088, PubMed 19329498

Yndestad A, Neurauter CG, Oie E, Forstrøm RJ, Vinge LE, Eide L, Luna L, Aukrust P, Bjørås M (2009)
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure
Mutat Res, 666 (1-2), 32-8
DOI 10.1016/j.mrfmmm.2009.03.008, PubMed 19481677

Publications 2008

Dahl CP, Gullestad L, Fevang B, Holm AM, Landrø L, Vinge LE, Fiane AE, Sandberg WJ, Otterdal K, Frøland SS, Damås JK, Halvorsen B, Aukrust P, Øie E, Yndestad A (2008)
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure
Eur J Heart Fail, 10 (4), 352-9
DOI 10.1016/j.ejheart.2008.02.010, PubMed 18353719

DeGeorge BR, Gao E, Boucher M, Vinge LE, Martini JS, Raake PW, Chuprun JK, Harris DM, Kim GW, Soltys S, Eckhart AD, Koch WJ (2008)
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress
Circulation, 117 (11), 1378-87
DOI 10.1161/CIRCULATIONAHA.107.752618, PubMed 18316484

Harris DM, Chen X, Pesant S, Cohn HI, MacDonnell SM, Boucher M, Vinge LE, Raake P, Moraca SR, Li D, Most P, Houser SR, Koch WJ, Eckhart AD (2008)
Inhibition of angiotensin II Gq signaling augments beta-adrenergic receptor mediated effects in a renal artery stenosis model of high blood pressure
J Mol Cell Cardiol, 46 (1), 100-7
DOI 10.1016/j.yjmcc.2008.09.708, PubMed 18930063

Martini JS, Raake P, Vinge LE, DeGeorge BR, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ (2008)
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes
Proc Natl Acad Sci U S A, 105 (34), 12457-62
DOI 10.1073/pnas.0803153105, PubMed 18711143

Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P (2008)
Endothelial S100A1 modulates vascular function via nitric oxide
Circ Res, 102 (7), 786-94
DOI 10.1161/CIRCRESAHA.108.172031, PubMed 18292599

Raake PW, Vinge LE, Gao E, Boucher M, Rengo G, Chen X, DeGeorge BR, Matkovich S, Houser SR, Most P, Eckhart AD, Dorn GW, Koch WJ (2008)
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure
Circ Res, 103 (4), 413-22
DOI 10.1161/CIRCRESAHA.107.168336, PubMed 18635825

Vinge LE, Raake PW, Koch WJ (2008)
Gene therapy in heart failure
Circ Res, 102 (12), 1458-70
DOI 10.1161/CIRCRESAHA.108.173195, PubMed 18566312

Publications 2007

Vinge LE, Andressen KW, Attramadal T, Andersen GØ, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H (2007)
Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
Mol Pharmacol, 72 (3), 582-91
DOI 10.1124/mol.107.035766, PubMed 17573483

Vinge LE, von Lueder TG, Aasum E, Qvigstad E, Gravning JA, How OJ, Edvardsen T, Bjørnerheim R, Ahmed MS, Mikkelsen BW, Oie E, Attramadal T, Skomedal T, Smiseth OA, Koch WJ, Larsen TS, Attramadal H (2007)
Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness
J Biol Chem, 283 (16), 10601-10
DOI 10.1074/jbc.M708912200, PubMed 18165681

Publications 2006

Ahmed MS, Øie E, Vinge LE, von Lueder TG, Attramadal T, Attramadal H (2006)
Induction of pulmonary connective tissue growth factor in heart failure is associated with pulmonary parenchymal and vascular remodeling
Cardiovasc Res, 74 (2), 323-33
DOI 10.1016/j.cardiores.2006.12.010, PubMed 17254558

Andersen GO, Oie E, Vinge LE, Yndestad A, Attramadal H, Skomedal T, Osnes JB (2006)
Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts
Basic Res Cardiol, 101 (6), 471-8
DOI 10.1007/s00395-006-0604-5, PubMed 16783486

Vinge LE (2006)
Myocardial G protein-coupled receptor kinases: distinct isoform specificities at receptors as basis for diverse roles in regulation of cardiac function
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 362, 1 b. (flere pag.)
BIBSYS 05229658x, ISBN 82-8072-661-6

Yndestad A, Vinge LE, Bjørnerheim R, Ueland T, Wang JE, Frøland SS, Attramadal H, Aukrust P, Oie E (2006)
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats
Eur J Heart Fail, 8 (8), 790-6
DOI 10.1016/j.ejheart.2006.02.007, PubMed 16549389

Publications 2004

Ahmed MS, Øie E, Vinge LE, Yndestad A, Øystein Andersen G, Andersson Y, Attramadal T, Attramadal H (2004)
Connective tissue growth factor--a novel mediator of angiotensin II-stimulated cardiac fibroblast activation in heart failure in rats
J Mol Cell Cardiol, 36 (3), 393-404
DOI 10.1016/j.yjmcc.2003.12.004, PubMed 15010278

von Lueder TG, Kjekshus H, Edvardsen T, ØIe E, Urheim S, Vinge LE, Ahmed MS, Smiseth OA, Attramadal H (2004)
Mechanisms of elevated plasma endothelin-1 in CHF: congestion increases pulmonary synthesis and secretion of endothelin-1
Cardiovasc Res, 63 (1), 41-50
DOI 10.1016/j.cardiores.2004.03.016, PubMed 15194460

Øie E, Vinge LE, Andersen GØ, Yndestad A, Krobert KA, Sandberg C, Ahmed MS, Haug T, Levy FO, Skomedal T, Attramadal H (2004)
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
J Mol Cell Cardiol, 38 (1), 145-51
DOI 10.1016/j.yjmcc.2004.10.009, PubMed 15623431

Publications 2003

Ahmed MS, Øie E, Vinge LE, Yndestad A, Andersen G GØ, Andersson Y, Attramadal T, Attramadal H (2003)
Induction of myocardial biglycan in heart failure in rats--an extracellular matrix component targeted by AT(1) receptor antagonism
Cardiovasc Res, 60 (3), 557-68
DOI 10.1016/j.cardiores.2003.08.017, PubMed 14659801

Publications 2001

Vinge LE, Øie E, Andersson Y, Grøgaard HK, Andersen G, Attramadal H (2001)
Myocardial distribution and regulation of GRK and beta-arrestin isoforms in congestive heart failure in rats
Am J Physiol Heart Circ Physiol, 281 (6), H2490-9
DOI 10.1152/ajpheart.2001.281.6.H2490, PubMed 11709416

Publications 2000

Oie E, Vinge LE, Yndestad A, Sandberg C, Grøgaard HK, Attramadal H (2000)
Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats
Circulation, 101 (4), 415-22
DOI 10.1161/01.cir.101.4.415, PubMed 10653834

Publications 1997

Oie E, Vinge LE, Tønnessen T, Grøgaard HK, Kjekshus H, Christensen G, Smiseth OA, Attramadal H (1997)
Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats
Am J Physiol, 273 (4), H1727-36
DOI 10.1152/ajpheart.1997.273.4.H1727, PubMed 9362237